ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
NIEGOPEA_00001 1.97e-164 - - - K - - - Transcriptional regulatory protein, C terminal
NIEGOPEA_00002 1.22e-156 yclK - - T - - - Histidine kinase
NIEGOPEA_00003 3.92e-169 yclK - - T - - - Histidine kinase
NIEGOPEA_00004 1.62e-123 - - - L - - - Psort location Cytoplasmic, score
NIEGOPEA_00005 3.46e-55 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NIEGOPEA_00006 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NIEGOPEA_00007 9.16e-138 vanZ - - V - - - VanZ like family
NIEGOPEA_00008 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
NIEGOPEA_00009 7.02e-311 - - - EGP - - - Major Facilitator
NIEGOPEA_00010 3.21e-89 - - - - - - - -
NIEGOPEA_00013 7.92e-247 ampC - - V - - - Beta-lactamase
NIEGOPEA_00014 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain
NIEGOPEA_00015 8.2e-145 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
NIEGOPEA_00016 4.43e-251 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NIEGOPEA_00017 5.31e-204 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NIEGOPEA_00018 8.5e-242 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NIEGOPEA_00019 2.61e-146 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NIEGOPEA_00020 7.4e-165 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
NIEGOPEA_00021 1.75e-35 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NIEGOPEA_00022 5.6e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NIEGOPEA_00023 1.13e-120 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NIEGOPEA_00024 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NIEGOPEA_00025 1.21e-219 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NIEGOPEA_00026 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NIEGOPEA_00027 2.1e-94 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
NIEGOPEA_00028 1.25e-41 - - - S - - - Protein of unknown function (DUF1146)
NIEGOPEA_00029 3.53e-229 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
NIEGOPEA_00030 3.34e-18 - - - S - - - DNA-directed RNA polymerase subunit beta
NIEGOPEA_00031 5.54e-69 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
NIEGOPEA_00032 1.26e-46 - - - S - - - Protein of unknown function (DUF2969)
NIEGOPEA_00033 1.85e-284 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
NIEGOPEA_00034 3.52e-106 uspA - - T - - - universal stress protein
NIEGOPEA_00035 9.34e-08 - - - - - - - -
NIEGOPEA_00036 1.59e-304 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
NIEGOPEA_00037 6.16e-109 - - - S - - - Protein of unknown function (DUF1694)
NIEGOPEA_00038 7.54e-143 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NIEGOPEA_00040 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NIEGOPEA_00041 6.1e-276 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
NIEGOPEA_00042 4.43e-291 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NIEGOPEA_00043 3.13e-159 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NIEGOPEA_00044 1.91e-230 - - - C - - - Glycerophosphoryl diester phosphodiesterase family
NIEGOPEA_00045 0.0 yoaB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
NIEGOPEA_00046 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NIEGOPEA_00047 1.35e-300 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NIEGOPEA_00048 2.59e-159 - - - S - - - Haloacid dehalogenase-like hydrolase
NIEGOPEA_00049 3.73e-143 radC - - L ko:K03630 - ko00000 DNA repair protein
NIEGOPEA_00050 3.11e-225 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
NIEGOPEA_00051 1.17e-188 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
NIEGOPEA_00052 3.99e-123 mreD - - - ko:K03571 - ko00000,ko03036 -
NIEGOPEA_00053 2.36e-19 - - - S - - - Protein of unknown function (DUF4044)
NIEGOPEA_00054 2.2e-68 - - - S - - - Protein of unknown function (DUF3397)
NIEGOPEA_00055 1.89e-100 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
NIEGOPEA_00056 1.02e-229 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NIEGOPEA_00057 3.95e-73 ftsL - - D - - - Cell division protein FtsL
NIEGOPEA_00058 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NIEGOPEA_00059 9e-227 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NIEGOPEA_00060 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NIEGOPEA_00061 9.56e-266 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NIEGOPEA_00062 4.49e-197 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NIEGOPEA_00063 5.2e-309 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NIEGOPEA_00064 3.29e-313 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NIEGOPEA_00065 9.26e-88 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NIEGOPEA_00066 1.36e-47 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
NIEGOPEA_00067 1.39e-187 ylmH - - S - - - S4 domain protein
NIEGOPEA_00068 4.46e-162 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
NIEGOPEA_00069 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NIEGOPEA_00070 1.37e-45 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
NIEGOPEA_00071 2.57e-133 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
NIEGOPEA_00072 6.32e-52 - - - - - - - -
NIEGOPEA_00073 1.44e-164 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NIEGOPEA_00074 3.68e-277 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
NIEGOPEA_00075 1.27e-76 XK27_04120 - - S - - - Putative amino acid metabolism
NIEGOPEA_00076 9.01e-278 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NIEGOPEA_00077 5.5e-162 pgm - - G - - - Phosphoglycerate mutase family
NIEGOPEA_00078 1.45e-150 - - - S - - - repeat protein
NIEGOPEA_00079 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NIEGOPEA_00080 6.58e-225 ytlR - - I - - - Diacylglycerol kinase catalytic domain
NIEGOPEA_00081 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NIEGOPEA_00082 3.08e-47 ykzG - - S - - - Belongs to the UPF0356 family
NIEGOPEA_00083 9.73e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NIEGOPEA_00084 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
NIEGOPEA_00085 1.36e-268 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NIEGOPEA_00086 1.63e-65 ylbG - - S - - - UPF0298 protein
NIEGOPEA_00087 1.23e-124 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
NIEGOPEA_00088 3.34e-112 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NIEGOPEA_00089 6.91e-235 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
NIEGOPEA_00090 7.81e-141 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
NIEGOPEA_00091 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
NIEGOPEA_00092 3.38e-227 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
NIEGOPEA_00093 1.8e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
NIEGOPEA_00094 2.9e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NIEGOPEA_00095 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NIEGOPEA_00096 9.52e-205 - - - - - - - -
NIEGOPEA_00097 2.45e-288 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NIEGOPEA_00098 1.21e-276 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NIEGOPEA_00099 3.55e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NIEGOPEA_00100 1.79e-132 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
NIEGOPEA_00101 1.62e-115 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NIEGOPEA_00102 1.1e-108 - - - - - - - -
NIEGOPEA_00104 5.91e-151 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
NIEGOPEA_00105 5.18e-110 - - - S - - - Domain of unknown function (DUF4767)
NIEGOPEA_00106 8.23e-277 - - - - - - - -
NIEGOPEA_00107 1.39e-156 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
NIEGOPEA_00108 1.53e-209 - - - - - - - -
NIEGOPEA_00109 8.59e-103 - - - K - - - DNA-templated transcription, initiation
NIEGOPEA_00110 1.74e-211 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NIEGOPEA_00111 9.04e-179 epsB - - M - - - biosynthesis protein
NIEGOPEA_00112 1.69e-157 ywqD - - D - - - Capsular exopolysaccharide family
NIEGOPEA_00113 3.8e-176 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
NIEGOPEA_00114 5.95e-104 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
NIEGOPEA_00115 4.81e-178 cps3J - - M - - - Domain of unknown function (DUF4422)
NIEGOPEA_00116 3.11e-156 - - GT4 M ko:K02840 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Glycosyl transferases group 1
NIEGOPEA_00117 1.92e-48 - - - S - - - O-antigen ligase like membrane protein
NIEGOPEA_00118 7.92e-64 - - - M - - - Glycosyltransferase like family 2
NIEGOPEA_00119 1.53e-58 - - - G - - - Protein of unknown function (DUF563)
NIEGOPEA_00120 2.79e-80 - - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
NIEGOPEA_00121 5.75e-127 - - - M - - - transferase activity, transferring glycosyl groups
NIEGOPEA_00122 4.68e-56 - - - H - - - Core-2/I-Branching enzyme
NIEGOPEA_00123 2.1e-270 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
NIEGOPEA_00124 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
NIEGOPEA_00125 2.58e-208 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_00126 4.3e-74 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_00129 6.6e-07 - - - - - - - -
NIEGOPEA_00130 6.4e-281 - - - KQ - - - helix_turn_helix, mercury resistance
NIEGOPEA_00131 6.41e-265 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NIEGOPEA_00132 2.53e-209 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NIEGOPEA_00133 1.21e-152 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NIEGOPEA_00134 1.11e-236 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NIEGOPEA_00135 7.56e-101 - - - S - - - AAA ATPase domain
NIEGOPEA_00136 1.3e-111 vsr - - L ko:K07458 - ko00000,ko01000,ko03400 DNA mismatch endonuclease Vsr
NIEGOPEA_00137 2.74e-08 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_00138 3.1e-15 - - - S - - - FRG
NIEGOPEA_00140 1.88e-47 licB2 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NIEGOPEA_00141 6.12e-162 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIEGOPEA_00142 4.22e-34 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
NIEGOPEA_00143 2.18e-296 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NIEGOPEA_00144 1.25e-135 - - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
NIEGOPEA_00145 5.79e-136 - - - - - - - -
NIEGOPEA_00146 3.6e-131 - - - S ko:K06926 - ko00000 AAA domain, putative AbiEii toxin, Type IV TA system
NIEGOPEA_00147 4.88e-208 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Peptidase family M48
NIEGOPEA_00149 5.83e-172 - - - - - - - -
NIEGOPEA_00150 4.42e-105 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
NIEGOPEA_00151 3.78e-92 - - - - - - - -
NIEGOPEA_00152 1.48e-90 - - - - - - - -
NIEGOPEA_00153 6.93e-88 - - - S - - - Domain of unknown function DUF1828
NIEGOPEA_00154 2.53e-157 - - - S - - - Rib/alpha-like repeat
NIEGOPEA_00155 2.03e-09 - - - - - - - -
NIEGOPEA_00156 1.06e-314 yagE - - E - - - amino acid
NIEGOPEA_00157 5.48e-150 - - - GM - - - NmrA-like family
NIEGOPEA_00158 1.15e-195 - - - L - - - Phage integrase, N-terminal SAM-like domain
NIEGOPEA_00159 3.55e-132 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
NIEGOPEA_00160 8.28e-222 iunH 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 inosine-uridine preferring nucleoside hydrolase
NIEGOPEA_00161 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NIEGOPEA_00162 8.87e-305 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NIEGOPEA_00163 0.0 oatA - - I - - - Acyltransferase
NIEGOPEA_00164 6.85e-226 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NIEGOPEA_00165 7.14e-185 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NIEGOPEA_00166 8.03e-63 - - - S - - - Lipopolysaccharide assembly protein A domain
NIEGOPEA_00167 3.88e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
NIEGOPEA_00168 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NIEGOPEA_00169 7.45e-36 - - - S - - - Protein of unknown function (DUF2929)
NIEGOPEA_00170 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
NIEGOPEA_00171 1.69e-231 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NIEGOPEA_00172 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
NIEGOPEA_00173 3.33e-211 yitL - - S ko:K00243 - ko00000 S1 domain
NIEGOPEA_00174 1.59e-213 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
NIEGOPEA_00175 1.95e-82 ribT - - K ko:K02859 - ko00000 acetyltransferase
NIEGOPEA_00176 1.23e-172 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NIEGOPEA_00177 1.59e-136 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NIEGOPEA_00178 4.82e-166 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NIEGOPEA_00179 1.08e-117 - - - M - - - Lysin motif
NIEGOPEA_00180 2.31e-125 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NIEGOPEA_00181 1.78e-152 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
NIEGOPEA_00182 6.93e-281 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
NIEGOPEA_00183 3.67e-312 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
NIEGOPEA_00184 1.37e-55 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NIEGOPEA_00185 2.89e-298 XK27_05225 - - S - - - Tetratricopeptide repeat protein
NIEGOPEA_00186 0.0 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
NIEGOPEA_00187 3.21e-175 - - - S - - - SIR2-like domain
NIEGOPEA_00188 4.78e-53 - - - S - - - SIR2-like domain
NIEGOPEA_00189 5.77e-193 - - - - - - - -
NIEGOPEA_00190 1.7e-133 - - - J ko:K10716 - ko00000,ko02000 Ion transport protein
NIEGOPEA_00191 4.7e-206 XK27_10395 - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NIEGOPEA_00192 2.86e-288 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NIEGOPEA_00193 2.78e-147 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
NIEGOPEA_00194 7.72e-195 degV3 - - S - - - Uncharacterised protein, DegV family COG1307
NIEGOPEA_00195 3.74e-48 yozE - - S - - - Belongs to the UPF0346 family
NIEGOPEA_00196 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
NIEGOPEA_00197 1.64e-202 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NIEGOPEA_00198 1.49e-170 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NIEGOPEA_00199 1.39e-195 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
NIEGOPEA_00200 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NIEGOPEA_00201 8.35e-315 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NIEGOPEA_00202 5.79e-217 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Phage integrase, N-terminal SAM-like domain
NIEGOPEA_00203 1.9e-115 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NIEGOPEA_00204 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NIEGOPEA_00205 5.87e-229 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
NIEGOPEA_00206 7.43e-131 - - - K - - - LysR substrate binding domain
NIEGOPEA_00207 5.82e-130 - - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
NIEGOPEA_00209 2.6e-96 - - - - - - - -
NIEGOPEA_00210 1.73e-227 - - - S - - - Conserved hypothetical protein 698
NIEGOPEA_00212 2.81e-139 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
NIEGOPEA_00213 3.1e-177 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
NIEGOPEA_00214 1.25e-107 - - - S - - - Pyridoxamine 5'-phosphate oxidase
NIEGOPEA_00215 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
NIEGOPEA_00216 1.76e-175 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
NIEGOPEA_00217 7.2e-84 - - - S - - - Protein of unknown function (DUF3021)
NIEGOPEA_00218 3.12e-95 - - - K - - - LytTr DNA-binding domain
NIEGOPEA_00219 0.0 - - - D - - - Domain of Unknown Function (DUF1542)
NIEGOPEA_00220 2.7e-139 ybbB - - S - - - Protein of unknown function (DUF1211)
NIEGOPEA_00221 3.46e-15 - - - S - - - reductase
NIEGOPEA_00222 3.89e-69 - - - S - - - reductase
NIEGOPEA_00223 6.22e-140 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
NIEGOPEA_00224 2e-149 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
NIEGOPEA_00225 7.15e-164 - - - T - - - Transcriptional regulatory protein, C terminal
NIEGOPEA_00226 3.02e-308 - - - T - - - GHKL domain
NIEGOPEA_00227 4.05e-119 ykoJ - - S - - - Peptidase propeptide and YPEB domain
NIEGOPEA_00228 3.38e-87 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
NIEGOPEA_00229 6.19e-120 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
NIEGOPEA_00230 9.53e-134 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
NIEGOPEA_00231 3.23e-315 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NIEGOPEA_00232 3.27e-125 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
NIEGOPEA_00233 2.26e-78 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
NIEGOPEA_00234 6.66e-236 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NIEGOPEA_00235 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NIEGOPEA_00236 6.13e-315 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NIEGOPEA_00237 4.17e-108 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NIEGOPEA_00238 1.5e-243 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NIEGOPEA_00239 2.89e-224 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NIEGOPEA_00240 6.86e-183 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NIEGOPEA_00241 3.16e-278 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NIEGOPEA_00242 4.28e-253 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NIEGOPEA_00244 1.75e-185 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
NIEGOPEA_00245 5.75e-285 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
NIEGOPEA_00246 2.79e-293 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NIEGOPEA_00247 5.72e-104 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
NIEGOPEA_00248 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
NIEGOPEA_00249 1.02e-71 yitW - - S - - - Iron-sulfur cluster assembly protein
NIEGOPEA_00250 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NIEGOPEA_00251 2.71e-180 - - - H - - - Nodulation protein S (NodS)
NIEGOPEA_00252 0.000705 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
NIEGOPEA_00253 1.35e-240 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NIEGOPEA_00254 3.82e-181 - - - S - - - PFAM Archaeal ATPase
NIEGOPEA_00255 7.49e-64 - - - - - - - -
NIEGOPEA_00256 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
NIEGOPEA_00258 3.26e-74 - - - S - - - Antibiotic biosynthesis monooxygenase
NIEGOPEA_00259 3.11e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NIEGOPEA_00260 8.96e-101 - - - S - - - Cupin domain
NIEGOPEA_00261 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
NIEGOPEA_00262 1.54e-91 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
NIEGOPEA_00263 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
NIEGOPEA_00264 9.5e-199 - - - C - - - Aldo keto reductase
NIEGOPEA_00265 7.23e-25 lysR - - K - - - Transcriptional regulator
NIEGOPEA_00266 2.52e-300 - - - L ko:K07478 - ko00000 AAA C-terminal domain
NIEGOPEA_00267 1.87e-218 - - - S ko:K07045 - ko00000 Amidohydrolase
NIEGOPEA_00268 6.22e-43 - - - - - - - -
NIEGOPEA_00269 1.09e-141 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
NIEGOPEA_00270 4.22e-211 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
NIEGOPEA_00271 3.74e-148 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
NIEGOPEA_00272 1.62e-149 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NIEGOPEA_00273 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NIEGOPEA_00274 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NIEGOPEA_00275 2.8e-229 - - - K - - - Transcriptional regulator
NIEGOPEA_00276 2.02e-219 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
NIEGOPEA_00277 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
NIEGOPEA_00278 7.91e-141 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NIEGOPEA_00279 1.28e-157 - - - S - - - Protein of unknown function (DUF1275)
NIEGOPEA_00280 9.84e-261 xerS - - L ko:K03733 - ko00000,ko03036 Belongs to the 'phage' integrase family
NIEGOPEA_00281 8.56e-129 lysR - - K - - - Transcriptional regulator
NIEGOPEA_00282 1.18e-197 - - - - - - - -
NIEGOPEA_00283 5.52e-209 - - - S - - - EDD domain protein, DegV family
NIEGOPEA_00284 1.32e-84 - - - - - - - -
NIEGOPEA_00285 0.0 FbpA - - K - - - Fibronectin-binding protein
NIEGOPEA_00286 0.0 carB1 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
NIEGOPEA_00287 3.49e-247 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NIEGOPEA_00288 2.37e-219 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NIEGOPEA_00289 7.17e-99 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NIEGOPEA_00290 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
NIEGOPEA_00291 2.96e-72 - - - - - - - -
NIEGOPEA_00292 1.38e-224 degV1 - - S - - - DegV family
NIEGOPEA_00293 1.41e-142 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
NIEGOPEA_00294 2.52e-304 cpdA - - S - - - Calcineurin-like phosphoesterase
NIEGOPEA_00295 8.95e-273 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
NIEGOPEA_00296 2.77e-94 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NIEGOPEA_00297 2.37e-129 ypsA - - S - - - Belongs to the UPF0398 family
NIEGOPEA_00298 5.29e-148 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NIEGOPEA_00299 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
NIEGOPEA_00300 7.81e-148 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NIEGOPEA_00301 1.39e-148 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
NIEGOPEA_00302 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
NIEGOPEA_00303 2.66e-117 ypmB - - S - - - Protein conserved in bacteria
NIEGOPEA_00304 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
NIEGOPEA_00305 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
NIEGOPEA_00306 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NIEGOPEA_00307 4.95e-217 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
NIEGOPEA_00308 2.03e-224 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
NIEGOPEA_00309 4.33e-260 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
NIEGOPEA_00310 1.35e-239 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NIEGOPEA_00311 0.0 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_00312 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
NIEGOPEA_00313 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
NIEGOPEA_00314 5.2e-21 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
NIEGOPEA_00315 2.89e-259 - - - G - - - Transmembrane secretion effector
NIEGOPEA_00316 5.51e-200 - 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 Aminoglycoside 3-N-acetyltransferase
NIEGOPEA_00317 5.97e-209 rbsU - - U ko:K06216 - ko00000,ko02000 ribose uptake protein RbsU
NIEGOPEA_00318 5.83e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NIEGOPEA_00319 2.62e-201 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NIEGOPEA_00320 5.99e-109 - - - S - - - ASCH
NIEGOPEA_00321 1.47e-156 - - - F - - - Phosphorylase superfamily
NIEGOPEA_00322 8.41e-107 - - - F - - - NUDIX domain
NIEGOPEA_00323 1.56e-188 - - - M - - - Phosphotransferase enzyme family
NIEGOPEA_00324 1.77e-115 - - - S - - - AAA domain
NIEGOPEA_00325 6.02e-208 yxaM - - EGP - - - Major facilitator Superfamily
NIEGOPEA_00326 1.07e-138 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
NIEGOPEA_00327 2.18e-112 - 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 Acetyltransferase (GNAT) family
NIEGOPEA_00328 4.16e-114 rimL - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NIEGOPEA_00329 3.03e-178 yfhR3 - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
NIEGOPEA_00330 0.0 - - - I - - - Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NIEGOPEA_00331 1.8e-56 - - - - - - - -
NIEGOPEA_00332 1.81e-156 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NIEGOPEA_00333 1.81e-78 - - - - - - - -
NIEGOPEA_00334 2.64e-63 - - - S - - - MazG-like family
NIEGOPEA_00335 8.11e-109 - - - FG - - - HIT domain
NIEGOPEA_00336 2.34e-102 - - - K - - - Acetyltransferase (GNAT) domain
NIEGOPEA_00337 1.14e-100 - - - - - - - -
NIEGOPEA_00338 6.92e-96 - - - - - - - -
NIEGOPEA_00339 2.14e-138 yokL3 - - J - - - Acetyltransferase (GNAT) domain
NIEGOPEA_00340 2.01e-57 - - - - ko:K07473 - ko00000,ko02048 -
NIEGOPEA_00341 8.69e-68 - - - S ko:K19157 - ko00000,ko01000,ko02048 endonuclease activity
NIEGOPEA_00342 2.29e-70 - - - - - - - -
NIEGOPEA_00343 0.0 - - - V - - - ABC transporter transmembrane region
NIEGOPEA_00344 5.8e-101 yfhC - - C - - - nitroreductase
NIEGOPEA_00345 2.14e-260 - - - P - - - Major Facilitator Superfamily
NIEGOPEA_00346 2.18e-305 - 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NIEGOPEA_00347 0.0 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_00348 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
NIEGOPEA_00349 9.91e-129 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NIEGOPEA_00350 4.44e-34 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NIEGOPEA_00351 8e-257 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NIEGOPEA_00352 1.34e-147 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NIEGOPEA_00353 1.11e-138 alkD - - L - - - DNA alkylation repair enzyme
NIEGOPEA_00354 4.88e-261 - - - M - - - Glycosyl transferases group 1
NIEGOPEA_00355 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NIEGOPEA_00356 2.22e-136 pncA - - Q - - - Isochorismatase family
NIEGOPEA_00357 7.82e-316 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_00358 3.27e-118 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NIEGOPEA_00359 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
NIEGOPEA_00360 3.31e-262 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NIEGOPEA_00361 9.79e-296 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NIEGOPEA_00362 1.18e-226 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
NIEGOPEA_00363 3.04e-119 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NIEGOPEA_00364 6.47e-214 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NIEGOPEA_00365 1.01e-165 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NIEGOPEA_00366 9.13e-153 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NIEGOPEA_00367 0.0 - - - I - - - Protein of unknown function (DUF2974)
NIEGOPEA_00368 1.1e-191 yxeH - - S - - - hydrolase
NIEGOPEA_00369 1.32e-228 - - - S - - - DUF218 domain
NIEGOPEA_00370 2.14e-64 ybjQ - - S - - - Belongs to the UPF0145 family
NIEGOPEA_00371 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
NIEGOPEA_00372 2.18e-221 - - - - - - - -
NIEGOPEA_00373 1.28e-167 - - - - - - - -
NIEGOPEA_00374 2.02e-131 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NIEGOPEA_00375 5.06e-31 - - - - - - - -
NIEGOPEA_00376 2.65e-108 - - - L - - - transposase activity
NIEGOPEA_00377 9.27e-15 - - - S ko:K07118 - ko00000 NAD(P)H-binding
NIEGOPEA_00378 4.93e-82 - - - - - - - -
NIEGOPEA_00379 1.1e-49 - - - - - - - -
NIEGOPEA_00380 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
NIEGOPEA_00381 2.06e-192 - - - - - - - -
NIEGOPEA_00382 3.15e-219 - - - L - - - Psort location Cytoplasmic, score
NIEGOPEA_00383 3.06e-177 - - - - - - - -
NIEGOPEA_00384 2.58e-186 - - - - - - - -
NIEGOPEA_00385 6.31e-160 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NIEGOPEA_00386 4.24e-78 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
NIEGOPEA_00387 5.38e-313 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
NIEGOPEA_00388 1.35e-194 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NIEGOPEA_00389 1.84e-155 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
NIEGOPEA_00390 4.82e-193 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
NIEGOPEA_00391 3.81e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NIEGOPEA_00392 7.1e-152 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
NIEGOPEA_00393 6.84e-147 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
NIEGOPEA_00394 0.0 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_00395 8.64e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NIEGOPEA_00396 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NIEGOPEA_00397 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
NIEGOPEA_00398 9.03e-229 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
NIEGOPEA_00399 1.38e-175 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
NIEGOPEA_00400 2.36e-216 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NIEGOPEA_00401 2.05e-115 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NIEGOPEA_00402 2.02e-221 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
NIEGOPEA_00403 1.09e-76 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
NIEGOPEA_00404 8.33e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
NIEGOPEA_00405 3.44e-200 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NIEGOPEA_00406 9.17e-70 yitW - - S - - - Iron-sulfur cluster assembly protein
NIEGOPEA_00407 8.64e-196 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NIEGOPEA_00408 6.14e-155 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
NIEGOPEA_00409 3.17e-202 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NIEGOPEA_00410 7.69e-134 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NIEGOPEA_00411 4.55e-12 - - - - - - - -
NIEGOPEA_00412 0.0 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_00413 1.39e-181 - - - E - - - GDSL-like Lipase/Acylhydrolase family
NIEGOPEA_00414 6.34e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
NIEGOPEA_00415 2.62e-282 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NIEGOPEA_00416 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NIEGOPEA_00417 9.01e-314 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
NIEGOPEA_00418 8.26e-96 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NIEGOPEA_00419 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NIEGOPEA_00420 1.91e-85 - - - - - - - -
NIEGOPEA_00421 6.78e-220 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
NIEGOPEA_00422 3.6e-112 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NIEGOPEA_00423 0.0 - - - S - - - Bacterial membrane protein, YfhO
NIEGOPEA_00424 0.0 aha1 - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
NIEGOPEA_00425 7.29e-244 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
NIEGOPEA_00426 0.0 - - - S - - - Putative threonine/serine exporter
NIEGOPEA_00427 2.09e-215 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NIEGOPEA_00428 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
NIEGOPEA_00429 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NIEGOPEA_00430 1.74e-117 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NIEGOPEA_00431 2.94e-238 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NIEGOPEA_00432 9.46e-200 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NIEGOPEA_00433 2.33e-87 - - - L - - - nuclease
NIEGOPEA_00434 7.26e-183 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
NIEGOPEA_00435 2e-64 - - - K - - - Helix-turn-helix domain
NIEGOPEA_00436 4.2e-240 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NIEGOPEA_00437 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
NIEGOPEA_00438 6.36e-37 - - - S - - - Sugar efflux transporter for intercellular exchange
NIEGOPEA_00439 2.48e-311 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NIEGOPEA_00440 1.03e-131 - - - I - - - PAP2 superfamily
NIEGOPEA_00443 1.03e-202 lysR5 - - K - - - LysR substrate binding domain
NIEGOPEA_00444 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
NIEGOPEA_00445 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
NIEGOPEA_00446 5.35e-123 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NIEGOPEA_00447 9.15e-240 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NIEGOPEA_00448 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NIEGOPEA_00449 0.0 potE - - E - - - Amino Acid
NIEGOPEA_00450 2.41e-123 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NIEGOPEA_00451 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
NIEGOPEA_00452 4.45e-157 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
NIEGOPEA_00453 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NIEGOPEA_00454 1.73e-252 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NIEGOPEA_00455 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
NIEGOPEA_00456 6.8e-111 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NIEGOPEA_00457 4.4e-246 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NIEGOPEA_00458 8.8e-139 - - - L - - - Belongs to the 'phage' integrase family
NIEGOPEA_00460 5.39e-22 ansR - - K - - - Transcriptional regulator
NIEGOPEA_00461 3.86e-12 - - - S - - - Helix-turn-helix domain
NIEGOPEA_00466 3.06e-39 - - - - - - - -
NIEGOPEA_00470 4.87e-121 - - - S - - - GyrI-like small molecule binding domain
NIEGOPEA_00471 0.0 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
NIEGOPEA_00472 1.6e-222 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
NIEGOPEA_00473 4.06e-212 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NIEGOPEA_00474 4.75e-80 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NIEGOPEA_00475 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NIEGOPEA_00476 1.32e-63 - - - J - - - ribosomal protein
NIEGOPEA_00477 1.08e-62 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
NIEGOPEA_00478 2.72e-281 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
NIEGOPEA_00479 3.4e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
NIEGOPEA_00480 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NIEGOPEA_00481 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NIEGOPEA_00482 1.09e-293 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
NIEGOPEA_00483 3.37e-178 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
NIEGOPEA_00484 2.41e-175 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NIEGOPEA_00485 2.02e-120 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NIEGOPEA_00486 4.12e-168 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
NIEGOPEA_00487 8.74e-236 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NIEGOPEA_00488 7.4e-181 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
NIEGOPEA_00489 1.73e-246 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
NIEGOPEA_00490 3.9e-150 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
NIEGOPEA_00491 5.17e-293 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
NIEGOPEA_00492 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NIEGOPEA_00493 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NIEGOPEA_00494 4.85e-41 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
NIEGOPEA_00495 1.7e-45 ynzC - - S - - - UPF0291 protein
NIEGOPEA_00496 4.53e-146 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NIEGOPEA_00497 1.77e-150 ung2 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
NIEGOPEA_00498 2.61e-96 apfA 3.6.1.61 - F ko:K18445 ko00230,map00230 ko00000,ko00001,ko01000 Nudix hydrolase
NIEGOPEA_00499 2.63e-151 sipS3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NIEGOPEA_00500 2.61e-76 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NIEGOPEA_00501 3.7e-175 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
NIEGOPEA_00502 2.07e-123 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NIEGOPEA_00503 1.37e-59 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
NIEGOPEA_00504 1.99e-291 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NIEGOPEA_00505 3.48e-75 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NIEGOPEA_00506 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NIEGOPEA_00507 4.07e-257 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NIEGOPEA_00508 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
NIEGOPEA_00509 1.29e-159 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NIEGOPEA_00510 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NIEGOPEA_00511 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NIEGOPEA_00512 1.06e-206 oppC5 - - P ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NIEGOPEA_00513 3.25e-225 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NIEGOPEA_00514 8.34e-229 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NIEGOPEA_00515 9.96e-244 oppD - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NIEGOPEA_00516 1.53e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NIEGOPEA_00517 1.23e-231 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NIEGOPEA_00518 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NIEGOPEA_00519 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
NIEGOPEA_00520 8.29e-75 yloU - - S - - - Asp23 family, cell envelope-related function
NIEGOPEA_00521 6.36e-34 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
NIEGOPEA_00522 4.31e-156 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
NIEGOPEA_00523 7.8e-156 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
NIEGOPEA_00524 6.45e-209 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NIEGOPEA_00525 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
NIEGOPEA_00526 1.83e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
NIEGOPEA_00527 1.74e-307 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NIEGOPEA_00528 2.28e-222 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NIEGOPEA_00529 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NIEGOPEA_00530 3.3e-43 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NIEGOPEA_00531 2.57e-144 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
NIEGOPEA_00532 7.04e-63 - - - - - - - -
NIEGOPEA_00533 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
NIEGOPEA_00534 5.29e-199 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
NIEGOPEA_00535 6.21e-207 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NIEGOPEA_00536 7.86e-46 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NIEGOPEA_00537 0.0 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NIEGOPEA_00538 3.69e-196 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NIEGOPEA_00539 1e-88 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NIEGOPEA_00540 1.21e-93 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
NIEGOPEA_00541 1.73e-132 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NIEGOPEA_00542 1.57e-259 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
NIEGOPEA_00543 9.89e-64 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
NIEGOPEA_00544 1.67e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
NIEGOPEA_00545 1.9e-79 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
NIEGOPEA_00546 4.65e-193 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NIEGOPEA_00547 2.8e-271 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
NIEGOPEA_00548 1.17e-17 - - - - - - - -
NIEGOPEA_00549 2.18e-83 - - - - - - - -
NIEGOPEA_00550 4.18e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
NIEGOPEA_00551 4.76e-119 - - - S - - - ECF-type riboflavin transporter, S component
NIEGOPEA_00552 7.71e-191 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
NIEGOPEA_00553 1.44e-72 - - - - - - - -
NIEGOPEA_00554 3.72e-159 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
NIEGOPEA_00555 5.98e-244 - - - S - - - Predicted membrane protein (DUF2207)
NIEGOPEA_00556 4.17e-77 - - - S - - - Predicted membrane protein (DUF2207)
NIEGOPEA_00557 8.29e-222 - - - I - - - Carboxylesterase family
NIEGOPEA_00558 3e-75 - - - K - - - helix_turn_helix, arabinose operon control protein
NIEGOPEA_00559 1.93e-81 - - - K - - - AraC-like ligand binding domain
NIEGOPEA_00560 2.8e-171 - - - GK - - - ROK family
NIEGOPEA_00561 2.08e-13 - - - GK - - - ROK family
NIEGOPEA_00562 1.67e-104 - - - M - - - Sortase family
NIEGOPEA_00565 0.0 pepC4 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
NIEGOPEA_00566 2.03e-80 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
NIEGOPEA_00567 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NIEGOPEA_00568 3.24e-102 - - - K - - - MerR HTH family regulatory protein
NIEGOPEA_00569 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
NIEGOPEA_00570 7.6e-121 - - - S - - - Domain of unknown function (DUF4811)
NIEGOPEA_00571 8.08e-190 - - - M - - - Glycosyl transferase family 2
NIEGOPEA_00572 8.04e-139 - - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
NIEGOPEA_00573 8.07e-91 - - - - - - - -
NIEGOPEA_00574 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NIEGOPEA_00575 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
NIEGOPEA_00577 3.13e-179 - - - S - - - haloacid dehalogenase-like hydrolase
NIEGOPEA_00578 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
NIEGOPEA_00579 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NIEGOPEA_00580 3.85e-292 sptS - - T - - - Histidine kinase
NIEGOPEA_00581 1.75e-150 dltr - - K - - - response regulator
NIEGOPEA_00582 2.44e-148 - - - T - - - Region found in RelA / SpoT proteins
NIEGOPEA_00583 1.84e-210 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
NIEGOPEA_00584 3.2e-91 - - - O - - - OsmC-like protein
NIEGOPEA_00585 0.0 - - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NIEGOPEA_00586 6.12e-232 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NIEGOPEA_00587 9.98e-215 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NIEGOPEA_00588 2.72e-208 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
NIEGOPEA_00589 1.21e-206 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
NIEGOPEA_00590 9.59e-101 ykuP - - C ko:K03839 - ko00000 Flavodoxin
NIEGOPEA_00591 3.74e-115 gtcA1 - - S - - - Teichoic acid glycosylation protein
NIEGOPEA_00592 2.58e-275 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NIEGOPEA_00594 3.15e-219 - - - L - - - Psort location Cytoplasmic, score
NIEGOPEA_00596 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIEGOPEA_00597 5.69e-280 yfmL - - L - - - DEAD DEAH box helicase
NIEGOPEA_00598 1.34e-175 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
NIEGOPEA_00599 2.31e-295 - - - E ko:K03294 - ko00000 amino acid
NIEGOPEA_00600 2.11e-133 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
NIEGOPEA_00601 4.03e-301 yhdP - - S - - - Transporter associated domain
NIEGOPEA_00602 6.35e-160 - - - - - - - -
NIEGOPEA_00603 6.34e-147 - - - C - - - nitroreductase
NIEGOPEA_00604 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
NIEGOPEA_00605 3.01e-180 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
NIEGOPEA_00606 1.29e-70 - - - S - - - Enterocin A Immunity
NIEGOPEA_00607 2.4e-172 gntR - - K - - - UbiC transcription regulator-associated domain protein
NIEGOPEA_00608 1.61e-223 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
NIEGOPEA_00609 3.67e-162 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NIEGOPEA_00610 4.72e-212 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NIEGOPEA_00611 1.98e-110 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
NIEGOPEA_00612 0.0 - - - S - - - C4-dicarboxylate anaerobic carrier
NIEGOPEA_00613 3.15e-219 - - - L - - - Psort location Cytoplasmic, score
NIEGOPEA_00615 1.8e-78 yvbK - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NIEGOPEA_00616 8.28e-152 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
NIEGOPEA_00617 6.89e-181 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NIEGOPEA_00618 3.29e-191 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NIEGOPEA_00619 1.19e-199 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
NIEGOPEA_00620 8.44e-217 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
NIEGOPEA_00621 5.51e-206 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
NIEGOPEA_00622 3.23e-124 - - - K - - - Acetyltransferase (GNAT) domain
NIEGOPEA_00623 1.54e-164 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NIEGOPEA_00624 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
NIEGOPEA_00625 2.16e-204 - - - S - - - Phospholipase, patatin family
NIEGOPEA_00626 0.0 pacL - - P - - - Cation transporter/ATPase, N-terminus
NIEGOPEA_00628 7.62e-68 - - - S - - - Enterocin A Immunity
NIEGOPEA_00632 8.17e-285 - - - S - - - CAAX protease self-immunity
NIEGOPEA_00633 1.09e-61 - - - S - - - Enterocin A Immunity
NIEGOPEA_00635 4.72e-134 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
NIEGOPEA_00636 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NIEGOPEA_00637 1.58e-87 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NIEGOPEA_00638 1.29e-257 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
NIEGOPEA_00642 4.62e-31 - - - S - - - Bacteriocin class II with double-glycine leader peptide
NIEGOPEA_00643 6.99e-136 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
NIEGOPEA_00644 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NIEGOPEA_00645 2.69e-185 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NIEGOPEA_00646 4.71e-285 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
NIEGOPEA_00647 7.35e-47 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NIEGOPEA_00648 5.46e-259 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
NIEGOPEA_00649 1.35e-20 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NIEGOPEA_00651 6.41e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
NIEGOPEA_00653 8.35e-110 - - - S - - - Putative adhesin
NIEGOPEA_00654 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NIEGOPEA_00655 7.08e-167 treR - - K ko:K03486 - ko00000,ko03000 UTRA
NIEGOPEA_00656 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NIEGOPEA_00657 1.68e-85 - - - - - - - -
NIEGOPEA_00658 3.24e-139 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NIEGOPEA_00659 1.75e-141 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NIEGOPEA_00660 4.31e-191 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NIEGOPEA_00661 2.12e-174 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NIEGOPEA_00662 6.33e-188 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NIEGOPEA_00663 0.0 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
NIEGOPEA_00664 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NIEGOPEA_00665 4.2e-87 - - - K - - - Transcriptional regulator, MarR family
NIEGOPEA_00666 5.71e-201 - - - S - - - Alpha beta hydrolase
NIEGOPEA_00667 1.97e-277 - - - EGP ko:K08196 - ko00000,ko02000 Major Facilitator
NIEGOPEA_00668 0.0 - - - E - - - Peptidase family C69
NIEGOPEA_00669 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
NIEGOPEA_00670 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
NIEGOPEA_00671 0.0 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphatidylserine decarboxylase family
NIEGOPEA_00672 0.0 - - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
NIEGOPEA_00673 0.0 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphatidylserine decarboxylase family
NIEGOPEA_00674 4.05e-165 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
NIEGOPEA_00675 3.97e-145 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NIEGOPEA_00677 7.25e-265 pepA - - E - - - M42 glutamyl aminopeptidase
NIEGOPEA_00678 2.04e-107 - - - - - - - -
NIEGOPEA_00679 6.45e-91 rmaE - - K - - - helix_turn_helix multiple antibiotic resistance protein
NIEGOPEA_00680 7.75e-40 - - - - - - - -
NIEGOPEA_00681 1.67e-274 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
NIEGOPEA_00682 1.18e-315 - - - E - - - amino acid
NIEGOPEA_00683 0.0 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 Contains amino acid permease domain
NIEGOPEA_00684 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
NIEGOPEA_00685 0.0 - - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
NIEGOPEA_00686 0.0 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 Contains amino acid permease domain
NIEGOPEA_00687 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
NIEGOPEA_00688 0.0 - - - E - - - Phospholipase B
NIEGOPEA_00689 8.12e-144 - - - I - - - Acid phosphatase homologues
NIEGOPEA_00690 1.53e-216 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
NIEGOPEA_00691 0.0 lacG 3.2.1.21, 3.2.1.85 - G ko:K01220,ko:K05350 ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NIEGOPEA_00692 3.31e-300 lacE 2.7.1.207 - G ko:K02787,ko:K02788 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system, EIIC
NIEGOPEA_00693 1.72e-60 lacE 2.7.1.207 - G ko:K02787,ko:K02788 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system, EIIC
NIEGOPEA_00694 1.62e-71 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
NIEGOPEA_00695 6.21e-151 lacT - - K ko:K02531 - ko00000,ko03000 CAT RNA binding domain
NIEGOPEA_00696 1.17e-136 - 5.3.1.26 - G ko:K01819 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 Ribose/Galactose Isomerase
NIEGOPEA_00697 3.14e-94 lacA 5.3.1.26 - G ko:K01819 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 Ribose/Galactose Isomerase
NIEGOPEA_00698 5.79e-170 - - - K ko:K02530 - ko00000,ko03000 DeoR C terminal sensor domain
NIEGOPEA_00699 1.18e-308 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
NIEGOPEA_00700 7.26e-205 - - - K - - - Transcriptional regulator
NIEGOPEA_00701 1.63e-192 - - - S - - - hydrolase
NIEGOPEA_00702 1.43e-112 - - - S - - - Protein of unknown function (DUF1440)
NIEGOPEA_00703 4.87e-191 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
NIEGOPEA_00704 8.41e-260 - - - S - - - PFAM Archaeal ATPase
NIEGOPEA_00705 5.22e-102 - - - K - - - acetyltransferase
NIEGOPEA_00706 0.0 qacA - - EGP - - - Major Facilitator
NIEGOPEA_00707 0.0 qacA - - EGP - - - Major Facilitator
NIEGOPEA_00708 9.83e-185 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NIEGOPEA_00709 1.28e-181 - - - S ko:K07052 - ko00000 CAAX amino terminal protease
NIEGOPEA_00710 5.06e-209 - - - S ko:K07088 - ko00000 Membrane transport protein
NIEGOPEA_00711 5.17e-129 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
NIEGOPEA_00712 2.01e-245 - - - S - - - Bacteriocin helveticin-J
NIEGOPEA_00713 6.44e-283 - - - P - - - Voltage gated chloride channel
NIEGOPEA_00714 5.09e-107 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
NIEGOPEA_00715 1.29e-110 - - - L ko:K07491 - ko00000 Transposase IS200 like
NIEGOPEA_00716 0.0 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
NIEGOPEA_00717 3.85e-144 ylbE - - GM - - - NAD(P)H-binding
NIEGOPEA_00718 2.15e-161 - - - F - - - Glutamine amidotransferase class-I
NIEGOPEA_00719 1.02e-121 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
NIEGOPEA_00721 3.3e-164 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Sigma-54 factor, core binding domain
NIEGOPEA_00722 8.75e-146 - - - S ko:K07507 - ko00000,ko02000 MgtC family
NIEGOPEA_00723 2.69e-190 ptsD - - G ko:K02796,ko:K19509 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
NIEGOPEA_00724 6.42e-176 ptsC - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
NIEGOPEA_00725 7.29e-106 ptsB 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NIEGOPEA_00726 1.61e-71 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NIEGOPEA_00727 0.0 - - - K - - - Sigma-54 interaction domain
NIEGOPEA_00728 1.67e-68 - - - K - - - Sigma-54 interaction domain
NIEGOPEA_00729 1.05e-60 - - - - - - - -
NIEGOPEA_00730 3.79e-221 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
NIEGOPEA_00731 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
NIEGOPEA_00732 1.13e-219 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NIEGOPEA_00733 1.14e-194 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NIEGOPEA_00734 4.14e-176 - - - - - - - -
NIEGOPEA_00735 6.88e-279 - - - S - - - Protein of unknown function (DUF2974)
NIEGOPEA_00736 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
NIEGOPEA_00737 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
NIEGOPEA_00738 1.19e-150 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
NIEGOPEA_00739 0.0 mdr - - EGP - - - Major Facilitator
NIEGOPEA_00740 2.13e-276 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NIEGOPEA_00746 5.77e-81 yugI - - J ko:K07570 - ko00000 general stress protein
NIEGOPEA_00747 1.23e-228 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
NIEGOPEA_00748 8.39e-151 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
NIEGOPEA_00749 3.32e-135 - - - S - - - Protein of unknown function (DUF1461)
NIEGOPEA_00750 1.2e-190 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NIEGOPEA_00751 1.45e-126 yutD - - S - - - Protein of unknown function (DUF1027)
NIEGOPEA_00752 1.44e-64 sasH 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NIEGOPEA_00753 2.75e-264 sasH 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NIEGOPEA_00754 1.39e-74 - - - - - - - -
NIEGOPEA_00755 0.0 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
NIEGOPEA_00756 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
NIEGOPEA_00757 0.0 pbp1B 2.4.1.129 GT51 M ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin binding protein transpeptidase domain
NIEGOPEA_00758 4.41e-224 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
NIEGOPEA_00759 1.72e-267 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
NIEGOPEA_00760 8.01e-66 - - - - - - - -
NIEGOPEA_00761 2.92e-37 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NIEGOPEA_00762 9.92e-177 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
NIEGOPEA_00763 1.02e-278 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NIEGOPEA_00764 3.15e-219 - - - L - - - Psort location Cytoplasmic, score
NIEGOPEA_00765 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
NIEGOPEA_00766 0.0 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_00767 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
NIEGOPEA_00768 3.6e-152 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NIEGOPEA_00769 1.23e-186 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NIEGOPEA_00770 2.11e-89 yslB - - S - - - Protein of unknown function (DUF2507)
NIEGOPEA_00771 3.15e-219 - - - L - - - Psort location Cytoplasmic, score
NIEGOPEA_00772 8.93e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NIEGOPEA_00773 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NIEGOPEA_00774 1.96e-120 cvpA - - S - - - Colicin V production protein
NIEGOPEA_00775 3.49e-55 yrzB - - S - - - Belongs to the UPF0473 family
NIEGOPEA_00776 1.01e-95 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NIEGOPEA_00777 1.08e-56 yrzL - - S - - - Belongs to the UPF0297 family
NIEGOPEA_00778 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NIEGOPEA_00779 1.61e-294 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NIEGOPEA_00780 1.24e-234 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
NIEGOPEA_00781 6.98e-265 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NIEGOPEA_00782 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NIEGOPEA_00783 0.0 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_00784 6.84e-75 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
NIEGOPEA_00785 3.28e-236 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NIEGOPEA_00786 3.1e-132 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NIEGOPEA_00787 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NIEGOPEA_00788 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NIEGOPEA_00789 0.0 nisT - - V ko:K06147,ko:K20485 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 ABC transporter
NIEGOPEA_00790 4.62e-103 - - - - - - - -
NIEGOPEA_00791 1.83e-20 - - - K - - - Helix-turn-helix domain
NIEGOPEA_00792 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NIEGOPEA_00793 3.69e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NIEGOPEA_00795 6.76e-168 - - - S - - - membrane
NIEGOPEA_00796 5.72e-104 - - - K - - - LytTr DNA-binding domain
NIEGOPEA_00797 1.22e-54 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NIEGOPEA_00798 8.93e-130 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
NIEGOPEA_00799 1.48e-252 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
NIEGOPEA_00800 1.45e-150 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NIEGOPEA_00801 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
NIEGOPEA_00802 6.1e-313 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NIEGOPEA_00803 1.33e-101 - - - - - - - -
NIEGOPEA_00804 1.57e-192 - - - K - - - Helix-turn-helix XRE-family like proteins
NIEGOPEA_00805 8.98e-311 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NIEGOPEA_00806 9.69e-317 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NIEGOPEA_00807 8.15e-240 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NIEGOPEA_00808 0.0 eriC - - P ko:K03281 - ko00000 chloride
NIEGOPEA_00809 2.34e-148 - - - - - - - -
NIEGOPEA_00810 1.58e-91 - - - - - - - -
NIEGOPEA_00811 5.23e-271 - - - D - - - nuclear chromosome segregation
NIEGOPEA_00812 4.98e-250 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NIEGOPEA_00813 7.45e-124 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
NIEGOPEA_00814 2.9e-168 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
NIEGOPEA_00815 2.99e-102 - - - S - - - ECF transporter, substrate-specific component
NIEGOPEA_00816 2.14e-176 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
NIEGOPEA_00817 1.98e-197 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NIEGOPEA_00818 3.33e-78 yabA - - L - - - Involved in initiation control of chromosome replication
NIEGOPEA_00819 1.9e-195 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NIEGOPEA_00820 1.24e-68 yaaQ - - S - - - Cyclic-di-AMP receptor
NIEGOPEA_00821 1.45e-145 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NIEGOPEA_00822 3.03e-44 - - - S - - - Protein of unknown function (DUF2508)
NIEGOPEA_00823 5.97e-138 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NIEGOPEA_00824 2.22e-67 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NIEGOPEA_00825 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NIEGOPEA_00826 2.48e-111 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NIEGOPEA_00827 1.63e-64 - - - S - - - Protein conserved in bacteria
NIEGOPEA_00828 1.64e-186 - - - - - - - -
NIEGOPEA_00829 1.65e-31 - - - - - - - -
NIEGOPEA_00830 6.45e-144 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
NIEGOPEA_00831 4.45e-42 - - - - - - - -
NIEGOPEA_00832 0.0 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_00833 6.33e-181 - 2.1.1.172 - J ko:K00564,ko:K10716 - ko00000,ko01000,ko02000,ko03009 Ion channel
NIEGOPEA_00834 3.25e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NIEGOPEA_00835 1.78e-107 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NIEGOPEA_00836 5.46e-186 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
NIEGOPEA_00837 3.7e-149 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter
NIEGOPEA_00838 3.38e-140 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
NIEGOPEA_00839 2.48e-159 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NIEGOPEA_00840 1.89e-90 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NIEGOPEA_00841 5.22e-131 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
NIEGOPEA_00842 8.06e-17 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NIEGOPEA_00843 1.48e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NIEGOPEA_00844 2.96e-243 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NIEGOPEA_00845 1.18e-291 - - - G - - - Major Facilitator Superfamily
NIEGOPEA_00846 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NIEGOPEA_00847 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
NIEGOPEA_00848 5.9e-46 - - - - - - - -
NIEGOPEA_00849 5.1e-114 - - - K ko:K03091 - ko00000,ko03021 sigma factor activity
NIEGOPEA_00850 1.28e-176 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NIEGOPEA_00851 5.57e-104 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NIEGOPEA_00852 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NIEGOPEA_00853 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NIEGOPEA_00854 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NIEGOPEA_00855 3.82e-133 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
NIEGOPEA_00856 1.63e-237 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NIEGOPEA_00857 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
NIEGOPEA_00858 5.61e-253 - - - M - - - transferase activity, transferring glycosyl groups
NIEGOPEA_00859 3.35e-213 - - - S - - - glycosyl transferase family 2
NIEGOPEA_00860 2.07e-32 - - - UW - - - Tetratricopeptide repeat
NIEGOPEA_00862 1.29e-257 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
NIEGOPEA_00863 0.0 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NIEGOPEA_00864 0.0 gtf1 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NIEGOPEA_00865 0.0 secA2 - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NIEGOPEA_00866 5.26e-200 asp3 - - S ko:K12270 - ko00000,ko02044 Accessory Sec secretory system ASP3
NIEGOPEA_00867 0.0 asp2 - - S ko:K12269 - ko00000,ko02044 Accessory Sec system GspB-transporter
NIEGOPEA_00868 0.0 asp1 - - S ko:K12268 - ko00000,ko02044 Accessory Sec system protein Asp1
NIEGOPEA_00869 5.37e-271 secY2 - - U - - - Part of the accessory SecA2 SecY2 system specifically required for export of
NIEGOPEA_00870 0.0 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 Contains amino acid permease domain
NIEGOPEA_00871 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
NIEGOPEA_00872 6.92e-236 - - - S - - - AAA domain
NIEGOPEA_00873 3.24e-158 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NIEGOPEA_00874 1.44e-17 - - - - - - - -
NIEGOPEA_00875 2.36e-51 - - - - - - - -
NIEGOPEA_00876 6.48e-267 - - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
NIEGOPEA_00877 8e-197 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
NIEGOPEA_00878 4.17e-67 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
NIEGOPEA_00879 1.29e-165 - - - G - - - Belongs to the phosphoglycerate mutase family
NIEGOPEA_00880 8.91e-142 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
NIEGOPEA_00881 8.93e-191 - - - GM - - - NmrA-like family
NIEGOPEA_00882 9.62e-128 - - - K - - - Transcriptional regulator C-terminal region
NIEGOPEA_00883 5.66e-258 - - - S - - - membrane
NIEGOPEA_00884 5.07e-151 - - - GM - - - NAD(P)H-binding
NIEGOPEA_00885 3.26e-160 - - - K ko:K12410 - ko00000,ko01000 Sir2 family
NIEGOPEA_00886 5.54e-168 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_00887 1.13e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
NIEGOPEA_00888 1.08e-101 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NIEGOPEA_00889 1.29e-191 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NIEGOPEA_00890 2.37e-179 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NIEGOPEA_00891 5.29e-264 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
NIEGOPEA_00892 3.43e-204 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NIEGOPEA_00893 4.31e-195 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NIEGOPEA_00894 1.91e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
NIEGOPEA_00895 7.63e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIEGOPEA_00896 4.46e-81 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NIEGOPEA_00897 1.92e-73 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NIEGOPEA_00898 1.89e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
NIEGOPEA_00899 4.46e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NIEGOPEA_00900 4.87e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NIEGOPEA_00901 1.2e-299 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NIEGOPEA_00902 5.78e-92 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
NIEGOPEA_00903 3.44e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
NIEGOPEA_00904 9.33e-107 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NIEGOPEA_00905 1.09e-74 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NIEGOPEA_00906 3.04e-122 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NIEGOPEA_00907 9.28e-89 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NIEGOPEA_00908 1.73e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NIEGOPEA_00909 6.1e-124 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NIEGOPEA_00910 1.18e-46 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NIEGOPEA_00911 6.02e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NIEGOPEA_00912 7.74e-56 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NIEGOPEA_00913 2.92e-34 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
NIEGOPEA_00914 3e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NIEGOPEA_00915 3.69e-157 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NIEGOPEA_00916 9.07e-73 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NIEGOPEA_00917 6.08e-63 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NIEGOPEA_00918 1.99e-198 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NIEGOPEA_00919 7.29e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NIEGOPEA_00920 1.57e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
NIEGOPEA_00921 3.57e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NIEGOPEA_00922 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
NIEGOPEA_00923 0.0 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_00924 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NIEGOPEA_00925 8.05e-106 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NIEGOPEA_00926 3.6e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NIEGOPEA_00927 1.16e-140 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
NIEGOPEA_00928 1.48e-217 - - - L - - - Psort location Cytoplasmic, score
NIEGOPEA_00929 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIEGOPEA_00930 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIEGOPEA_00931 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NIEGOPEA_00935 1.86e-84 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NIEGOPEA_00936 2.24e-76 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NIEGOPEA_00937 1.44e-117 - - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NIEGOPEA_00938 7.76e-59 - - - V - - - Type II restriction enzyme, methylase subunits
NIEGOPEA_00940 2.5e-15 yeeA - - V - - - Type II restriction enzyme, methylase subunits
NIEGOPEA_00942 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
NIEGOPEA_00943 2.17e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NIEGOPEA_00944 3.19e-206 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NIEGOPEA_00945 4.07e-268 - - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
NIEGOPEA_00946 4.49e-143 - - - L - - - Resolvase, N-terminal
NIEGOPEA_00947 0.0 - - - S - - - membrane
NIEGOPEA_00948 0.0 - - - S - - - membrane
NIEGOPEA_00949 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NIEGOPEA_00950 1.7e-311 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NIEGOPEA_00951 4.65e-80 - - - J ko:K07571 - ko00000 S1 RNA binding domain
NIEGOPEA_00952 1.52e-77 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
NIEGOPEA_00953 3.62e-46 yabO - - J - - - S4 domain protein
NIEGOPEA_00954 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NIEGOPEA_00955 4.45e-133 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NIEGOPEA_00956 1.14e-231 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NIEGOPEA_00957 3.03e-158 - - - S - - - (CBS) domain
NIEGOPEA_00958 5.18e-273 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NIEGOPEA_00959 1.75e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NIEGOPEA_00960 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NIEGOPEA_00961 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NIEGOPEA_00962 8.98e-55 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
NIEGOPEA_00963 0.0 - - - E - - - amino acid
NIEGOPEA_00964 1.04e-172 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NIEGOPEA_00965 3.67e-184 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NIEGOPEA_00966 1.14e-230 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
NIEGOPEA_00967 8.26e-290 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NIEGOPEA_00968 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NIEGOPEA_00969 1.19e-177 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
NIEGOPEA_00970 3.15e-219 - - - L - - - Psort location Cytoplasmic, score
NIEGOPEA_00971 1.7e-101 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
NIEGOPEA_00972 1.46e-42 ydeP - - K - - - Transcriptional regulator, HxlR family
NIEGOPEA_00973 4.04e-103 - - - - - - - -
NIEGOPEA_00974 7.02e-105 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
NIEGOPEA_00975 7.55e-53 - - - - - - - -
NIEGOPEA_00976 1.75e-259 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
NIEGOPEA_00977 0.0 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
NIEGOPEA_00978 0.0 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NIEGOPEA_00979 2.53e-123 - - - - - - - -
NIEGOPEA_00980 2.63e-73 ywnA - - K - - - Transcriptional regulator
NIEGOPEA_00981 3.6e-112 - - - K - - - Acetyltransferase (GNAT) domain
NIEGOPEA_00982 3.27e-83 - - - S - - - Protein of unknown function (DUF3021)
NIEGOPEA_00983 9.54e-97 - - - K - - - LytTr DNA-binding domain
NIEGOPEA_00984 2.01e-187 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
NIEGOPEA_00985 4.65e-194 - - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NIEGOPEA_00986 0.0 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_00987 0.0 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_00988 7.69e-278 - - - S - - - Membrane
NIEGOPEA_00989 1.3e-86 yjdF3 - - S - - - Protein of unknown function (DUF2992)
NIEGOPEA_00990 2.31e-122 - - - K - - - Bacterial regulatory proteins, tetR family
NIEGOPEA_00991 3.76e-145 - - - S - - - NADPH-dependent FMN reductase
NIEGOPEA_00992 4.22e-219 - - - K - - - Helix-turn-helix
NIEGOPEA_00993 1.79e-122 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
NIEGOPEA_00994 2.91e-139 - - - K - - - transcriptional regulator
NIEGOPEA_00996 0.0 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_00997 2.63e-239 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NIEGOPEA_00998 3.64e-76 ydeP - - K - - - Transcriptional regulator, HxlR family
NIEGOPEA_00999 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
NIEGOPEA_01000 2.16e-167 - - - K - - - Psort location CytoplasmicMembrane, score
NIEGOPEA_01001 1.17e-136 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NIEGOPEA_01002 8.56e-204 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
NIEGOPEA_01003 8e-71 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
NIEGOPEA_01004 4.39e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NIEGOPEA_01005 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NIEGOPEA_01006 1.03e-90 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NIEGOPEA_01007 7.07e-97 - - - S - - - Domain of unknown function (DUF1934)
NIEGOPEA_01008 0.0 - - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NIEGOPEA_01009 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
NIEGOPEA_01010 3.19e-53 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
NIEGOPEA_01011 3.99e-197 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NIEGOPEA_01012 0.0 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NIEGOPEA_01013 7.34e-290 malE - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NIEGOPEA_01014 1.36e-268 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NIEGOPEA_01015 4.64e-150 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
NIEGOPEA_01016 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
NIEGOPEA_01017 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NIEGOPEA_01018 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
NIEGOPEA_01019 5.01e-226 yvdE - - K - - - helix_turn _helix lactose operon repressor
NIEGOPEA_01020 2.27e-222 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NIEGOPEA_01021 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NIEGOPEA_01022 1.91e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
NIEGOPEA_01023 1.22e-48 veg - - S - - - Biofilm formation stimulator VEG
NIEGOPEA_01024 1.15e-206 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NIEGOPEA_01025 4.59e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NIEGOPEA_01026 3.86e-190 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
NIEGOPEA_01027 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NIEGOPEA_01028 1.21e-244 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_01029 5.01e-233 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
NIEGOPEA_01030 3.58e-128 - - - S ko:K06872 - ko00000 TPM domain
NIEGOPEA_01031 9.68e-119 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 MafB19-like deaminase
NIEGOPEA_01032 2.46e-247 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NIEGOPEA_01033 1.03e-149 - - - E - - - Belongs to the SOS response-associated peptidase family
NIEGOPEA_01035 8.03e-151 - - - - - - - -
NIEGOPEA_01036 1.2e-203 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
NIEGOPEA_01037 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NIEGOPEA_01038 0.0 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIEGOPEA_01039 3.44e-70 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NIEGOPEA_01040 7.13e-56 - - - - - - - -
NIEGOPEA_01041 3.56e-68 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
NIEGOPEA_01042 2.81e-175 - - - K ko:K03492 - ko00000,ko03000 UTRA
NIEGOPEA_01043 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NIEGOPEA_01044 1.86e-94 - - - S - - - Domain of unknown function (DUF3284)
NIEGOPEA_01045 6.9e-167 - - - K ko:K03489 - ko00000,ko03000 UTRA
NIEGOPEA_01046 1.85e-316 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIEGOPEA_01047 2.35e-107 - - - - - - - -
NIEGOPEA_01048 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NIEGOPEA_01049 1.24e-95 - - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NIEGOPEA_01050 3.85e-98 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NIEGOPEA_01051 1.06e-58 - - - - - - - -
NIEGOPEA_01052 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
NIEGOPEA_01053 5.93e-156 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NIEGOPEA_01054 0.0 pepC1 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
NIEGOPEA_01056 7.25e-306 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NIEGOPEA_01057 0.0 XK27_08315 - - M - - - Sulfatase
NIEGOPEA_01058 3.45e-145 plsY1 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NIEGOPEA_01059 1.59e-268 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NIEGOPEA_01060 9.65e-218 yqhA - - G - - - Aldose 1-epimerase
NIEGOPEA_01061 3.83e-196 - - - U ko:K05340 - ko00000,ko02000 sugar transport
NIEGOPEA_01062 6.21e-152 - - - - - - - -
NIEGOPEA_01063 7.72e-228 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
NIEGOPEA_01064 9.65e-95 - - - S - - - GtrA-like protein
NIEGOPEA_01065 4.38e-56 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NIEGOPEA_01066 6.15e-62 - - - S - - - HicB_like antitoxin of bacterial toxin-antitoxin system
NIEGOPEA_01067 2.23e-171 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NIEGOPEA_01068 2.4e-97 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
NIEGOPEA_01069 6.79e-184 - - - - - - - -
NIEGOPEA_01070 8.33e-182 - - - - - - - -
NIEGOPEA_01071 1.01e-228 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
NIEGOPEA_01072 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
NIEGOPEA_01073 6.56e-184 - 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
NIEGOPEA_01074 0.0 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
NIEGOPEA_01075 0.0 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NIEGOPEA_01076 3.38e-46 - - - S - - - Protein of unknown function (DUF2922)
NIEGOPEA_01077 3.41e-37 - - - - - - - -
NIEGOPEA_01078 1.44e-176 - - - - - - - -
NIEGOPEA_01079 4.33e-95 - - - - - - - -
NIEGOPEA_01080 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
NIEGOPEA_01081 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
NIEGOPEA_01082 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
NIEGOPEA_01083 0.0 - - - S - - - Bacterial membrane protein, YfhO
NIEGOPEA_01084 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
NIEGOPEA_01085 0.0 fruC 2.7.1.202 - GT ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NIEGOPEA_01086 7.3e-216 fruK-1 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
NIEGOPEA_01087 1.55e-173 rpl - - K - - - Helix-turn-helix domain, rpiR family
NIEGOPEA_01088 0.0 - - - D - - - transport
NIEGOPEA_01089 2.95e-238 lacD 4.1.2.40 - G ko:K01635 ko00052,ko01100,ko02024,map00052,map01100,map02024 ko00000,ko00001,ko01000 Belongs to the aldolase LacD family
NIEGOPEA_01090 7.1e-291 yqjV - - EGP - - - Major Facilitator Superfamily
NIEGOPEA_01091 4.42e-292 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
NIEGOPEA_01092 6.48e-136 yitW - - S - - - Iron-sulfur cluster assembly protein
NIEGOPEA_01093 1.51e-177 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NIEGOPEA_01094 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
NIEGOPEA_01095 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
NIEGOPEA_01096 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NIEGOPEA_01097 0.0 - - - S - - - Calcineurin-like phosphoesterase
NIEGOPEA_01098 3.38e-109 - - - - - - - -
NIEGOPEA_01099 6.11e-189 - - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NIEGOPEA_01100 1.11e-169 phnB - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NIEGOPEA_01101 1.28e-181 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NIEGOPEA_01102 1.16e-215 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
NIEGOPEA_01104 6.03e-114 usp5 - - T - - - universal stress protein
NIEGOPEA_01105 8.74e-192 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NIEGOPEA_01106 3.53e-169 - - - K - - - UTRA domain
NIEGOPEA_01107 1.76e-128 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NIEGOPEA_01108 1.56e-113 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
NIEGOPEA_01109 5.08e-282 - - - S - - - zinc-ribbon domain
NIEGOPEA_01110 2.66e-88 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NIEGOPEA_01111 1.02e-190 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
NIEGOPEA_01112 8.1e-191 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
NIEGOPEA_01113 3.93e-109 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NIEGOPEA_01114 5.34e-291 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
NIEGOPEA_01115 1.44e-276 agaS - - G ko:K02082 - ko00000,ko01000 SIS domain
NIEGOPEA_01116 2.69e-167 - - - K ko:K03710 - ko00000,ko03000 UTRA
NIEGOPEA_01117 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
NIEGOPEA_01118 6.18e-199 - - - I - - - alpha/beta hydrolase fold
NIEGOPEA_01119 1.38e-156 yibF - - S - - - overlaps another CDS with the same product name
NIEGOPEA_01120 8.19e-216 yibE - - S - - - overlaps another CDS with the same product name
NIEGOPEA_01121 0.0 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
NIEGOPEA_01122 2.79e-144 - - - - - - - -
NIEGOPEA_01123 2.62e-263 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
NIEGOPEA_01124 0.0 - - - S - - - Cysteine-rich secretory protein family
NIEGOPEA_01125 1.09e-159 - - - - - - - -
NIEGOPEA_01126 1.01e-148 - - - K - - - Bacterial regulatory proteins, tetR family
NIEGOPEA_01127 4.11e-308 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
NIEGOPEA_01128 6.1e-230 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NIEGOPEA_01129 2.78e-82 - - - - - - - -
NIEGOPEA_01130 3.44e-161 - - - S - - - Alpha/beta hydrolase family
NIEGOPEA_01131 5.52e-204 epsV - - S - - - glycosyl transferase family 2
NIEGOPEA_01132 2.02e-220 - - - S - - - Protein of unknown function (DUF1002)
NIEGOPEA_01134 5.53e-180 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NIEGOPEA_01135 1.49e-224 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NIEGOPEA_01136 5.18e-159 yugP - - S ko:K06973 - ko00000 Putative neutral zinc metallopeptidase
NIEGOPEA_01137 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NIEGOPEA_01138 1.28e-103 - - - - - - - -
NIEGOPEA_01139 6.37e-170 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
NIEGOPEA_01140 1.48e-252 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
NIEGOPEA_01141 6.09e-113 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 6-O-methylguanine DNA methyltransferase, DNA binding domain
NIEGOPEA_01142 2.41e-165 terC - - P - - - Integral membrane protein TerC family
NIEGOPEA_01143 4.1e-84 yeaO - - S - - - Protein of unknown function, DUF488
NIEGOPEA_01144 6.19e-149 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
NIEGOPEA_01145 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NIEGOPEA_01146 3.97e-176 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NIEGOPEA_01147 5.01e-61 - - - - - - - -
NIEGOPEA_01148 1.65e-209 - - - L - - - HNH nucleases
NIEGOPEA_01149 1.11e-154 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
NIEGOPEA_01150 4.96e-270 - - - G - - - Glycosyl hydrolases family 8
NIEGOPEA_01151 2.59e-312 - - - M - - - Glycosyl transferase
NIEGOPEA_01153 6.23e-151 - - - - - - - -
NIEGOPEA_01154 1.14e-23 - - - - - - - -
NIEGOPEA_01155 7.84e-92 - - - S - - - Iron-sulphur cluster biosynthesis
NIEGOPEA_01156 4.27e-236 ysdE - - P - - - Citrate transporter
NIEGOPEA_01157 2.67e-125 lemA - - S ko:K03744 - ko00000 LemA family
NIEGOPEA_01158 1.2e-208 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
NIEGOPEA_01159 5.14e-216 - - - K - - - helix_turn_helix, arabinose operon control protein
NIEGOPEA_01160 5.59e-128 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
NIEGOPEA_01161 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NIEGOPEA_01162 6.57e-144 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
NIEGOPEA_01163 6.08e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NIEGOPEA_01164 6.78e-236 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
NIEGOPEA_01165 8.73e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
NIEGOPEA_01166 1.49e-186 yycI - - S - - - YycH protein
NIEGOPEA_01167 0.0 yycH - - S - - - YycH protein
NIEGOPEA_01168 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NIEGOPEA_01169 2.13e-167 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NIEGOPEA_01171 0.0 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_01173 1.4e-188 - - - I - - - Acyl-transferase
NIEGOPEA_01174 2.52e-199 arbx - - M - - - Glycosyl transferase family 8
NIEGOPEA_01175 8.41e-235 - - - M - - - Glycosyl transferase family 8
NIEGOPEA_01176 2.24e-239 - - - M - - - Glycosyl transferase family 8
NIEGOPEA_01177 3.48e-212 arbZ - - I - - - Phosphate acyltransferases
NIEGOPEA_01178 7.19e-314 - - - P - - - Major Facilitator Superfamily
NIEGOPEA_01179 0.0 - - - P - - - Major Facilitator Superfamily
NIEGOPEA_01180 3.19e-239 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
NIEGOPEA_01181 5.19e-111 - - - S - - - Peptidase propeptide and YPEB domain
NIEGOPEA_01182 8.35e-229 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
NIEGOPEA_01183 1.09e-171 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NIEGOPEA_01184 2.31e-311 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NIEGOPEA_01185 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
NIEGOPEA_01186 3.37e-221 - - - K - - - LysR substrate binding domain
NIEGOPEA_01187 0.0 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_01188 4.17e-256 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
NIEGOPEA_01189 3.15e-219 - - - L - - - Psort location Cytoplasmic, score
NIEGOPEA_01190 0.000673 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
NIEGOPEA_01191 8.11e-152 - - - M - - - domain protein
NIEGOPEA_01192 0.0 - - - M - - - domain protein
NIEGOPEA_01193 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
NIEGOPEA_01194 0.0 - - - S - - - domain, Protein
NIEGOPEA_01195 3.92e-246 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NIEGOPEA_01196 8.92e-136 - - - E - - - GDSL-like Lipase/Acylhydrolase
NIEGOPEA_01197 1.95e-272 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NIEGOPEA_01198 0.0 - 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 pyridine nucleotide-disulfide oxidoreductase
NIEGOPEA_01199 9.61e-228 ydbI - - K - - - AI-2E family transporter
NIEGOPEA_01200 2.5e-36 - - - - - - - -
NIEGOPEA_01201 3.74e-175 - - - S - - - Alpha beta hydrolase
NIEGOPEA_01202 0.0 - - - L - - - Helicase C-terminal domain protein
NIEGOPEA_01203 3.21e-207 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
NIEGOPEA_01204 2.6e-54 - - - S - - - Transglycosylase associated protein
NIEGOPEA_01205 1.5e-20 - - - S - - - CsbD-like
NIEGOPEA_01206 1.16e-212 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
NIEGOPEA_01207 6.07e-252 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
NIEGOPEA_01208 7.92e-274 XK27_02480 - - EGP - - - Major facilitator Superfamily
NIEGOPEA_01209 7.46e-199 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix XRE-family like proteins
NIEGOPEA_01210 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
NIEGOPEA_01211 2.04e-309 eriC - - P ko:K03281 - ko00000 chloride
NIEGOPEA_01212 0.0 fusA1 - - J - - - elongation factor G
NIEGOPEA_01213 3.37e-181 - - - K - - - Helix-turn-helix domain
NIEGOPEA_01214 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
NIEGOPEA_01215 1.07e-23 - - - - - - - -
NIEGOPEA_01216 3.05e-198 yitS - - S - - - EDD domain protein, DegV family
NIEGOPEA_01217 4.52e-178 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NIEGOPEA_01218 8.09e-169 - - - S - - - Protein of unknown function (DUF975)
NIEGOPEA_01219 7.91e-244 - - - EGP - - - Major Facilitator Superfamily
NIEGOPEA_01220 3.15e-256 - 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 Involved in molybdopterin and thiamine biosynthesis, family 2
NIEGOPEA_01221 8.33e-185 - - - K - - - Helix-turn-helix domain
NIEGOPEA_01222 7.46e-149 - - - S ko:K07118 - ko00000 NAD(P)H-binding
NIEGOPEA_01223 2.45e-212 - - - I - - - Acyltransferase
NIEGOPEA_01224 1.41e-287 - - - S - - - Sterol carrier protein domain
NIEGOPEA_01226 1.06e-314 steT - - E ko:K03294 - ko00000 amino acid
NIEGOPEA_01228 0.0 - - - - - - - -
NIEGOPEA_01229 1.14e-278 - - - I - - - Protein of unknown function (DUF2974)
NIEGOPEA_01230 1.27e-218 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
NIEGOPEA_01231 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
NIEGOPEA_01232 8.13e-99 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
NIEGOPEA_01233 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
NIEGOPEA_01234 1.42e-216 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
NIEGOPEA_01235 1.33e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NIEGOPEA_01236 5.89e-109 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NIEGOPEA_01237 4.55e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
NIEGOPEA_01238 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NIEGOPEA_01239 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NIEGOPEA_01240 7.88e-267 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NIEGOPEA_01241 5.33e-30 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
NIEGOPEA_01242 1.46e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NIEGOPEA_01243 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NIEGOPEA_01244 6.59e-23 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
NIEGOPEA_01245 8.89e-80 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NIEGOPEA_01246 4.86e-201 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NIEGOPEA_01247 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NIEGOPEA_01248 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NIEGOPEA_01249 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NIEGOPEA_01250 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NIEGOPEA_01251 0.0 eriC - - P ko:K03281 - ko00000 chloride
NIEGOPEA_01252 0.0 mutS1 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NIEGOPEA_01254 8.09e-206 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko01000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NIEGOPEA_01255 2.88e-267 pbuG - - S ko:K06901 - ko00000,ko02000 permease
NIEGOPEA_01256 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NIEGOPEA_01257 1.09e-90 - - - S - - - Iron-sulphur cluster biosynthesis
NIEGOPEA_01258 2.16e-295 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
NIEGOPEA_01259 1.46e-92 - - - K - - - Acetyltransferase (GNAT) domain
NIEGOPEA_01260 3.8e-312 ynbB - - P - - - aluminum resistance
NIEGOPEA_01261 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
NIEGOPEA_01262 0.0 - - - E - - - Amino acid permease
NIEGOPEA_01263 2.33e-207 - 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NIEGOPEA_01264 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NIEGOPEA_01265 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
NIEGOPEA_01266 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
NIEGOPEA_01267 3.13e-65 - - - S - - - Cupredoxin-like domain
NIEGOPEA_01268 6.19e-86 - - - S - - - Cupredoxin-like domain
NIEGOPEA_01269 4.11e-100 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Penicillinase repressor
NIEGOPEA_01270 7.04e-121 - - - - - - - -
NIEGOPEA_01271 5.36e-114 - - - - - - - -
NIEGOPEA_01272 7.23e-93 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
NIEGOPEA_01273 5.36e-102 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
NIEGOPEA_01274 5.61e-292 pbuG - - S ko:K06901 - ko00000,ko02000 permease
NIEGOPEA_01275 9.81e-297 pbuG - - S ko:K06901 - ko00000,ko02000 permease
NIEGOPEA_01276 7.38e-168 - - - K - - - helix_turn_helix, mercury resistance
NIEGOPEA_01277 6.61e-295 pbuG - - S ko:K06901 - ko00000,ko02000 permease
NIEGOPEA_01278 8.4e-17 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
NIEGOPEA_01279 1.12e-244 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
NIEGOPEA_01280 4e-162 dgk2 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
NIEGOPEA_01281 8.43e-155 dak 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
NIEGOPEA_01282 9.42e-173 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NIEGOPEA_01283 8.84e-207 - - - S - - - Aldo/keto reductase family
NIEGOPEA_01284 5.37e-169 - - - S ko:K07090 - ko00000 membrane transporter protein
NIEGOPEA_01285 0.0 pts32BC 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NIEGOPEA_01286 6.12e-69 pts32BC 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NIEGOPEA_01287 1.06e-203 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NIEGOPEA_01288 2.55e-247 yleB 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
NIEGOPEA_01289 4.62e-192 yleF - - K - - - Helix-turn-helix domain, rpiR family
NIEGOPEA_01290 1.75e-254 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
NIEGOPEA_01291 1.21e-215 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, phosphonate, periplasmic substrate-binding protein
NIEGOPEA_01292 0.0 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_01293 2.87e-225 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
NIEGOPEA_01294 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NIEGOPEA_01295 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NIEGOPEA_01296 1.9e-234 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
NIEGOPEA_01297 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
NIEGOPEA_01298 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NIEGOPEA_01299 3.18e-261 - - - S - - - DUF218 domain
NIEGOPEA_01300 4.83e-145 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NIEGOPEA_01301 3.6e-122 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
NIEGOPEA_01302 0.0 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
NIEGOPEA_01305 2.11e-113 yhaH - - S - - - Protein of unknown function (DUF805)
NIEGOPEA_01306 7.06e-147 - - - S - - - Protein of unknown function (DUF969)
NIEGOPEA_01307 5.84e-201 - - - S - - - Protein of unknown function (DUF979)
NIEGOPEA_01308 2.07e-155 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NIEGOPEA_01309 2.33e-47 - - - - - - - -
NIEGOPEA_01310 2.24e-204 mutR - - K - - - Helix-turn-helix XRE-family like proteins
NIEGOPEA_01311 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
NIEGOPEA_01312 1.81e-141 - - - S - - - Putative adhesin
NIEGOPEA_01313 1.19e-258 napA - - P - - - Sodium/hydrogen exchanger family
NIEGOPEA_01314 0.0 cadA - - P - - - P-type ATPase
NIEGOPEA_01315 1.37e-110 ykuL - - S - - - (CBS) domain
NIEGOPEA_01316 5.45e-61 - - - - - - - -
NIEGOPEA_01317 1.88e-66 - - - - - - - -
NIEGOPEA_01318 1.18e-78 - - - - - - - -
NIEGOPEA_01320 2.57e-272 - - - S - - - Membrane
NIEGOPEA_01321 6.13e-52 - - - - - - - -
NIEGOPEA_01322 9.7e-07 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
NIEGOPEA_01323 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIEGOPEA_01324 4.7e-303 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
NIEGOPEA_01325 5.16e-50 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIEGOPEA_01326 0.0 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NIEGOPEA_01327 7.18e-189 pbpX2 - - V - - - Beta-lactamase
NIEGOPEA_01328 0.0 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_01329 3.82e-274 - - - E - - - Major Facilitator Superfamily
NIEGOPEA_01330 2.11e-53 - - - - - - - -
NIEGOPEA_01331 6.12e-313 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIEGOPEA_01332 3.7e-208 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NIEGOPEA_01333 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 AAA domain (Cdc48 subfamily)
NIEGOPEA_01334 1.21e-244 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_01335 0.0 - - - E ko:K03294 - ko00000 Amino Acid
NIEGOPEA_01348 1.83e-232 manL 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NIEGOPEA_01349 1.23e-166 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
NIEGOPEA_01350 6.04e-220 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
NIEGOPEA_01351 4.98e-85 - - - S - - - Domain of unknown function (DUF956)
NIEGOPEA_01352 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
NIEGOPEA_01353 2.21e-296 yifK - - E ko:K03293 - ko00000 Amino acid permease
NIEGOPEA_01354 1.98e-175 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
NIEGOPEA_01355 3.49e-303 - - - E - - - amino acid
NIEGOPEA_01356 0.0 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_01357 7.01e-244 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
NIEGOPEA_01358 2.61e-205 - - - EG - - - EamA-like transporter family
NIEGOPEA_01359 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
NIEGOPEA_01360 3.43e-169 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
NIEGOPEA_01361 8.38e-192 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NIEGOPEA_01362 4.68e-187 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NIEGOPEA_01363 1.57e-236 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
NIEGOPEA_01364 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
NIEGOPEA_01365 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NIEGOPEA_01366 6.45e-47 - - - - - - - -
NIEGOPEA_01367 1.98e-203 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
NIEGOPEA_01368 2.2e-12 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
NIEGOPEA_01369 1.26e-241 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
NIEGOPEA_01370 7.28e-117 ymdB - - S - - - Macro domain protein
NIEGOPEA_01371 0.0 - - - V - - - ABC transporter transmembrane region
NIEGOPEA_01372 2.06e-161 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
NIEGOPEA_01373 3.53e-276 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
NIEGOPEA_01374 1.57e-200 - - - - - - - -
NIEGOPEA_01375 1.83e-92 aroD 1.1.1.25, 4.2.1.10 - E ko:K03785,ko:K13832 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 3-dehydroquinate dehydratase activity
NIEGOPEA_01376 7.26e-200 - - - C - - - Domain of unknown function (DUF4931)
NIEGOPEA_01377 5.67e-196 - - - K - - - Helix-turn-helix domain, rpiR family
NIEGOPEA_01378 6.15e-185 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
NIEGOPEA_01379 5.39e-217 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
NIEGOPEA_01380 2.81e-151 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
NIEGOPEA_01381 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIEGOPEA_01382 2.16e-208 - - - O - - - protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NIEGOPEA_01383 2.6e-165 - - - - - - - -
NIEGOPEA_01384 9.32e-67 - - - - - - - -
NIEGOPEA_01385 5.24e-181 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
NIEGOPEA_01386 6.89e-180 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
NIEGOPEA_01387 5.95e-147 - - - G - - - Phosphoglycerate mutase family
NIEGOPEA_01388 4.06e-145 - - - G - - - phosphoglycerate mutase
NIEGOPEA_01389 1.91e-119 - - - K - - - Bacterial regulatory proteins, tetR family
NIEGOPEA_01390 1.44e-234 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NIEGOPEA_01391 3.39e-151 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NIEGOPEA_01392 9.86e-201 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
NIEGOPEA_01393 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NIEGOPEA_01394 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NIEGOPEA_01395 4.44e-66 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NIEGOPEA_01396 4.48e-257 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NIEGOPEA_01397 1.36e-50 - - - - - - - -
NIEGOPEA_01398 1.45e-142 - - - K - - - WHG domain
NIEGOPEA_01399 3.69e-124 - 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
NIEGOPEA_01400 4.45e-128 azr 1.5.1.36 - S ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
NIEGOPEA_01401 9.02e-256 - 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
NIEGOPEA_01402 3.05e-192 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NIEGOPEA_01403 3.27e-228 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NIEGOPEA_01404 3.16e-125 cvpA - - S - - - Colicin V production protein
NIEGOPEA_01405 4.13e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
NIEGOPEA_01406 1.28e-197 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NIEGOPEA_01407 3.52e-177 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
NIEGOPEA_01408 9.01e-198 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NIEGOPEA_01409 7.4e-58 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
NIEGOPEA_01410 1.89e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NIEGOPEA_01411 5.43e-191 - - - S - - - Protein of unknown function (DUF1129)
NIEGOPEA_01412 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
NIEGOPEA_01413 0.0 ndvA - - V ko:K06147 - ko00000,ko02000 ABC transporter
NIEGOPEA_01414 2.39e-156 vanR - - K - - - response regulator
NIEGOPEA_01415 5.1e-264 - - - T - - - His Kinase A (phosphoacceptor) domain
NIEGOPEA_01416 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NIEGOPEA_01417 4.33e-183 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
NIEGOPEA_01418 2.08e-210 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NIEGOPEA_01419 1.58e-281 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NIEGOPEA_01420 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
NIEGOPEA_01421 1.38e-176 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
NIEGOPEA_01422 5.13e-214 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NIEGOPEA_01423 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
NIEGOPEA_01424 0.0 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NIEGOPEA_01425 4.1e-178 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
NIEGOPEA_01426 1.07e-57 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
NIEGOPEA_01427 3.29e-203 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NIEGOPEA_01428 1.56e-152 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NIEGOPEA_01429 1.03e-172 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
NIEGOPEA_01430 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
NIEGOPEA_01431 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
NIEGOPEA_01432 5.55e-267 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NIEGOPEA_01433 1.74e-53 - - - - - - - -
NIEGOPEA_01434 5.46e-81 - - - - - - - -
NIEGOPEA_01435 0.0 - - - S - - - ABC transporter
NIEGOPEA_01436 5.17e-176 - - - S - - - Putative threonine/serine exporter
NIEGOPEA_01437 2.22e-103 - - - S - - - Threonine/Serine exporter, ThrE
NIEGOPEA_01438 1.05e-53 - - - - - - - -
NIEGOPEA_01439 7.58e-79 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
NIEGOPEA_01440 6.52e-103 - - - - - - - -
NIEGOPEA_01441 2.91e-229 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NIEGOPEA_01442 1.35e-107 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
NIEGOPEA_01443 2.23e-142 - - - - - - - -
NIEGOPEA_01444 0.0 - - - S - - - O-antigen ligase like membrane protein
NIEGOPEA_01445 1.87e-58 - - - - - - - -
NIEGOPEA_01446 3.24e-126 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
NIEGOPEA_01447 1.43e-161 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
NIEGOPEA_01448 8.6e-292 - - - S - - - Putative peptidoglycan binding domain
NIEGOPEA_01449 3.69e-296 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NIEGOPEA_01450 0.0 - - - E - - - Amino Acid
NIEGOPEA_01451 2.68e-172 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NIEGOPEA_01452 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NIEGOPEA_01453 4.36e-162 gpm2 - - G - - - Phosphoglycerate mutase family
NIEGOPEA_01454 9.27e-36 - - - - - - - -
NIEGOPEA_01455 1.65e-69 - - - - - - - -
NIEGOPEA_01456 3.39e-191 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
NIEGOPEA_01457 0.0 ptsG 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
NIEGOPEA_01458 1.56e-162 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NIEGOPEA_01459 3.25e-185 - - - K - - - Helix-turn-helix domain, rpiR family
NIEGOPEA_01460 0.0 - 3.6.3.8 - P ko:K01537 - ko00000,ko01000 ATPase, P-type (transporting), HAD superfamily, subfamily IC
NIEGOPEA_01462 5.92e-150 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
NIEGOPEA_01463 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NIEGOPEA_01464 2.68e-154 - - - S - - - Peptidase_C39 like family
NIEGOPEA_01465 5.15e-130 - - - E - - - GDSL-like Lipase/Acylhydrolase
NIEGOPEA_01466 7.58e-210 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
NIEGOPEA_01467 4.59e-133 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NIEGOPEA_01468 0.0 - - - M - - - Rib/alpha-like repeat
NIEGOPEA_01469 3.42e-88 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NIEGOPEA_01470 6.49e-194 - - - EG - - - EamA-like transporter family
NIEGOPEA_01471 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NIEGOPEA_01472 1.02e-205 - 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NIEGOPEA_01473 2.27e-179 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
NIEGOPEA_01474 7.71e-186 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
NIEGOPEA_01475 1.27e-81 - - - - - - - -
NIEGOPEA_01476 2.3e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NIEGOPEA_01477 3.03e-257 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
NIEGOPEA_01478 2.08e-302 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NIEGOPEA_01479 2.32e-180 - - - S - - - PAS domain
NIEGOPEA_01480 3.28e-92 - - - K ko:K03710 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
NIEGOPEA_01481 1.31e-92 - 2.7.1.191 - K ko:K02745,ko:K02794,ko:K10984 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NIEGOPEA_01482 1.27e-164 - - - G ko:K02746,ko:K10985 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
NIEGOPEA_01483 4.66e-158 agaD - - G ko:K02747,ko:K02796,ko:K10986 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
NIEGOPEA_01484 3.65e-52 - - - G ko:K02744 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NIEGOPEA_01485 2.42e-69 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NIEGOPEA_01486 0.0 - - - GM ko:K13732 ko05100,map05100 ko00000,ko00001 domain, Protein
NIEGOPEA_01487 1.63e-186 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
NIEGOPEA_01488 2.3e-118 - - - S - - - PAS domain
NIEGOPEA_01489 2.2e-312 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
NIEGOPEA_01490 6.72e-97 - - - S - - - Protein of unknown function (DUF3290)
NIEGOPEA_01491 1.69e-143 yviA - - S - - - Protein of unknown function (DUF421)
NIEGOPEA_01492 6.86e-189 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NIEGOPEA_01493 2.6e-231 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 EXOIII
NIEGOPEA_01494 1.67e-252 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
NIEGOPEA_01495 7.22e-199 dkgB - - S - - - reductase
NIEGOPEA_01496 4.84e-196 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
NIEGOPEA_01497 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NIEGOPEA_01498 8.41e-260 malK - - P ko:K10112,ko:K17240 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
NIEGOPEA_01499 3.57e-201 - - - P ko:K02025 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
NIEGOPEA_01500 2.39e-189 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NIEGOPEA_01501 1.9e-313 - - - S - - - Zn-dependent metallo-hydrolase RNA specificity domain
NIEGOPEA_01502 9.33e-310 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NIEGOPEA_01503 4.76e-75 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
NIEGOPEA_01504 1.77e-98 yybA - - K - - - Transcriptional regulator
NIEGOPEA_01505 1.68e-109 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NIEGOPEA_01506 8.58e-103 yjcF - - S - - - Acetyltransferase (GNAT) domain
NIEGOPEA_01507 1.86e-213 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
NIEGOPEA_01508 1.55e-204 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
NIEGOPEA_01509 3.1e-125 yobS - - K - - - Bacterial regulatory proteins, tetR family
NIEGOPEA_01510 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
NIEGOPEA_01511 9.25e-178 - - - S - - - haloacid dehalogenase-like hydrolase
NIEGOPEA_01512 2.14e-163 - - - S - - - SNARE associated Golgi protein
NIEGOPEA_01513 8.27e-227 - - - - - - - -
NIEGOPEA_01514 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NIEGOPEA_01515 5.7e-199 plcR - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
NIEGOPEA_01516 1.92e-200 - - - I - - - alpha/beta hydrolase fold
NIEGOPEA_01517 1.47e-138 - - - S - - - SNARE associated Golgi protein
NIEGOPEA_01518 2.79e-131 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NIEGOPEA_01519 6.46e-302 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NIEGOPEA_01537 0.0 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_01538 6.09e-81 - - - - - - - -
NIEGOPEA_01550 1.91e-281 - 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyl transferase 4-like domain
NIEGOPEA_01551 1.18e-252 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
NIEGOPEA_01552 3.15e-232 mprF - - S ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NIEGOPEA_01553 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NIEGOPEA_01573 1.24e-312 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
NIEGOPEA_01574 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
NIEGOPEA_01575 3.15e-219 - - - L - - - Psort location Cytoplasmic, score
NIEGOPEA_01576 2.91e-94 - - - - - - - -
NIEGOPEA_01577 2.16e-106 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
NIEGOPEA_01578 9.59e-49 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
NIEGOPEA_01579 0.0 - - - S - - - TerB-C domain
NIEGOPEA_01580 2.81e-298 - - - P - - - P-loop Domain of unknown function (DUF2791)
NIEGOPEA_01581 0.0 - - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
NIEGOPEA_01582 7.28e-243 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NIEGOPEA_01583 1.65e-48 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2263)
NIEGOPEA_01584 1.79e-100 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2263)
NIEGOPEA_01585 1.69e-188 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
NIEGOPEA_01586 3.97e-311 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
NIEGOPEA_01587 8.5e-208 yvgN - - C - - - Aldo keto reductase
NIEGOPEA_01589 4.51e-118 - - - K - - - acetyltransferase
NIEGOPEA_01590 2.08e-77 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
NIEGOPEA_01591 1.04e-165 - - - S - - - Putative ABC-transporter type IV
NIEGOPEA_01592 0.0 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_01593 2.9e-165 - - - M - - - LysM domain protein
NIEGOPEA_01594 6.19e-147 - - - M - - - LysM domain protein
NIEGOPEA_01596 2.8e-48 - - - S - - - Bacterial protein of unknown function (DUF898)
NIEGOPEA_01597 1.21e-45 - - - K - - - SIS domain
NIEGOPEA_01598 4.21e-212 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 lactate/malate dehydrogenase, alpha/beta C-terminal domain
NIEGOPEA_01601 1.19e-69 XK27_05625 - - P - - - Rhodanese Homology Domain
NIEGOPEA_01602 2.15e-243 - - - - - - - -
NIEGOPEA_01603 2.57e-158 gntR1 - - K ko:K03710 - ko00000,ko03000 UTRA
NIEGOPEA_01604 1.44e-90 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
NIEGOPEA_01605 6.86e-174 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NIEGOPEA_01606 2.43e-264 - - - M - - - Glycosyl transferases group 1
NIEGOPEA_01607 0.0 - - - S - - - Glycosyltransferase like family 2
NIEGOPEA_01608 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NIEGOPEA_01609 9.12e-199 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NIEGOPEA_01610 0.0 spoVK - - O - - - ATPase family associated with various cellular activities (AAA)
NIEGOPEA_01611 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
NIEGOPEA_01612 9.14e-286 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NIEGOPEA_01613 0.0 epsU - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
NIEGOPEA_01614 1.34e-169 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
NIEGOPEA_01615 4.53e-110 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
NIEGOPEA_01617 4.82e-131 - - - S - - - ECF transporter, substrate-specific component
NIEGOPEA_01618 5.71e-145 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
NIEGOPEA_01619 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
NIEGOPEA_01620 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NIEGOPEA_01621 2.62e-263 camS - - S - - - sex pheromone
NIEGOPEA_01622 3.17e-65 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NIEGOPEA_01623 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NIEGOPEA_01624 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NIEGOPEA_01625 1.47e-212 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
NIEGOPEA_01627 1.33e-188 - - - S - - - hydrolase
NIEGOPEA_01628 0.0 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_01629 2.86e-08 - - - UW - - - Tetratricopeptide repeat
NIEGOPEA_01630 1.24e-211 - - - UW - - - Tetratricopeptide repeat
NIEGOPEA_01631 1.24e-58 - - - UW - - - Tetratricopeptide repeat
NIEGOPEA_01632 5.21e-35 - - - UW - - - Tetratricopeptide repeat
NIEGOPEA_01633 0.0 - - - M - - - family 8
NIEGOPEA_01634 0.0 - - - M - - - family 8
NIEGOPEA_01635 0.0 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_01636 5.44e-73 - - - M - - - family 8
NIEGOPEA_01637 0.0 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_01638 3.82e-152 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
NIEGOPEA_01639 2.45e-182 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
NIEGOPEA_01640 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NIEGOPEA_01641 2.56e-123 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
NIEGOPEA_01642 5.12e-207 XK27_10120 - - K - - - S-adenosyl-l-methionine hydroxide adenosyltransferase
NIEGOPEA_01643 1.56e-311 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
NIEGOPEA_01644 3.28e-166 spaF - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NIEGOPEA_01645 2.58e-155 - - - S ko:K01992,ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NIEGOPEA_01646 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NIEGOPEA_01647 2.19e-142 - - - - - - - -
NIEGOPEA_01648 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
NIEGOPEA_01649 1.35e-46 - - - C - - - Heavy-metal-associated domain
NIEGOPEA_01650 2.49e-121 dpsB - - P - - - Belongs to the Dps family
NIEGOPEA_01651 5.03e-148 fnr - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
NIEGOPEA_01652 1.77e-51 ung2 - - L - - - Uracil-DNA glycosylase
NIEGOPEA_01654 1.13e-248 flp - - V - - - Beta-lactamase
NIEGOPEA_01655 6.08e-180 - 2.7.1.95 - F ko:K00897 - ko00000,ko01000,ko01504 Belongs to the aminoglycoside phosphotransferase family
NIEGOPEA_01656 3.49e-102 - - - L - - - NUDIX domain
NIEGOPEA_01657 0.0 - - - S - - - M26 IgA1-specific Metallo-endopeptidase C-terminal region
NIEGOPEA_01663 4.1e-34 - - - - - - - -
NIEGOPEA_01665 4.3e-36 - - - - - - - -
NIEGOPEA_01671 5.05e-20 - - - - - - - -
NIEGOPEA_01672 2.41e-24 ansR - - K - - - Transcriptional regulator
NIEGOPEA_01673 3.7e-118 int3 - - L - - - Belongs to the 'phage' integrase family
NIEGOPEA_01674 3.74e-205 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NIEGOPEA_01675 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NIEGOPEA_01676 1.57e-73 yheA - - S - - - Belongs to the UPF0342 family
NIEGOPEA_01677 2.52e-282 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
NIEGOPEA_01678 0.0 yhaN - - L - - - AAA domain
NIEGOPEA_01679 1.25e-236 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
NIEGOPEA_01680 3.04e-203 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NIEGOPEA_01681 1.2e-47 - - - S - - - YtxH-like protein
NIEGOPEA_01682 2.56e-85 - - - - - - - -
NIEGOPEA_01683 2.38e-99 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
NIEGOPEA_01684 1.38e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NIEGOPEA_01685 2.45e-287 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NIEGOPEA_01686 1.77e-162 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NIEGOPEA_01687 1.19e-84 - - - - - - - -
NIEGOPEA_01688 4.72e-72 ytpP - - CO - - - Thioredoxin
NIEGOPEA_01689 3.58e-156 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NIEGOPEA_01690 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
NIEGOPEA_01691 1.96e-164 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
NIEGOPEA_01692 5.24e-169 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NIEGOPEA_01693 3.01e-311 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NIEGOPEA_01694 1.19e-154 vraR - - K ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
NIEGOPEA_01695 1.89e-293 degS 2.7.13.3 - F ko:K07683,ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Sensor histidine kinase
NIEGOPEA_01696 9.32e-225 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein domain
NIEGOPEA_01697 8.55e-99 - - - G ko:K02744 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NIEGOPEA_01698 9.23e-124 levB 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NIEGOPEA_01699 4.1e-190 levC - - M ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
NIEGOPEA_01700 3.99e-193 levD - - G ko:K02771 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
NIEGOPEA_01701 6.34e-66 - - - - - - - -
NIEGOPEA_01702 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NIEGOPEA_01703 8.18e-206 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NIEGOPEA_01704 3.74e-136 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NIEGOPEA_01705 1.2e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NIEGOPEA_01706 8.86e-303 dnaB2 - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
NIEGOPEA_01707 1.05e-199 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
NIEGOPEA_01708 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NIEGOPEA_01709 5.61e-98 - - - K - - - LytTr DNA-binding domain
NIEGOPEA_01710 1.43e-95 - - - S - - - Protein of unknown function (DUF3021)
NIEGOPEA_01711 3.73e-303 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NIEGOPEA_01712 1.29e-112 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NIEGOPEA_01713 9.64e-38 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
NIEGOPEA_01714 1.23e-75 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NIEGOPEA_01715 7.56e-242 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NIEGOPEA_01716 1.29e-112 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
NIEGOPEA_01717 1.37e-269 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
NIEGOPEA_01718 9.54e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NIEGOPEA_01719 8.88e-144 yqeK - - H - - - Hydrolase, HD family
NIEGOPEA_01720 4.36e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NIEGOPEA_01721 4.15e-279 ylbM - - S - - - Belongs to the UPF0348 family
NIEGOPEA_01722 1.28e-121 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
NIEGOPEA_01723 1.89e-169 csrR - - K - - - response regulator
NIEGOPEA_01724 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NIEGOPEA_01725 9.51e-217 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NIEGOPEA_01726 8.53e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
NIEGOPEA_01727 3.14e-178 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NIEGOPEA_01728 1.19e-82 yodB - - K - - - Transcriptional regulator, HxlR family
NIEGOPEA_01729 9.43e-260 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NIEGOPEA_01730 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NIEGOPEA_01731 5.27e-260 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NIEGOPEA_01732 5.34e-97 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NIEGOPEA_01733 0.0 - - - S - - - membrane
NIEGOPEA_01734 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NIEGOPEA_01735 3.09e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NIEGOPEA_01736 6.82e-128 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NIEGOPEA_01737 2.67e-153 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
NIEGOPEA_01738 3.31e-47 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
NIEGOPEA_01739 2.09e-76 yqhL - - P - - - Rhodanese-like protein
NIEGOPEA_01740 1.18e-26 - - - S - - - Protein of unknown function (DUF3042)
NIEGOPEA_01741 2.54e-215 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NIEGOPEA_01742 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
NIEGOPEA_01743 7.77e-261 - - - EGP - - - Major Facilitator Superfamily
NIEGOPEA_01744 5.24e-190 supH - - S - - - haloacid dehalogenase-like hydrolase
NIEGOPEA_01746 1.56e-229 ybcH - - D ko:K06889 - ko00000 Alpha beta
NIEGOPEA_01747 6.12e-278 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
NIEGOPEA_01748 4.68e-280 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
NIEGOPEA_01749 4.65e-277 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
NIEGOPEA_01750 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NIEGOPEA_01751 4.46e-187 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
NIEGOPEA_01752 1.37e-146 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
NIEGOPEA_01753 1.37e-115 - - - - - - - -
NIEGOPEA_01754 9.44e-99 - - - - - - - -
NIEGOPEA_01755 2.23e-200 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
NIEGOPEA_01756 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NIEGOPEA_01757 2.17e-59 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
NIEGOPEA_01758 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
NIEGOPEA_01759 1.02e-34 - - - - - - - -
NIEGOPEA_01760 7.45e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
NIEGOPEA_01761 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NIEGOPEA_01762 0.0 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_01763 3.15e-219 - - - L - - - Psort location Cytoplasmic, score
NIEGOPEA_01764 2.87e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NIEGOPEA_01765 1.15e-153 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NIEGOPEA_01766 6e-212 coiA - - S ko:K06198 - ko00000 Competence protein
NIEGOPEA_01767 2.2e-139 yjbH - - Q - - - Thioredoxin
NIEGOPEA_01768 2.51e-143 - - - S - - - CYTH
NIEGOPEA_01769 1.7e-146 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
NIEGOPEA_01770 3.58e-197 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NIEGOPEA_01771 1.08e-217 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NIEGOPEA_01772 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
NIEGOPEA_01773 6.98e-306 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
NIEGOPEA_01774 6.1e-256 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
NIEGOPEA_01775 1.2e-88 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
NIEGOPEA_01776 8.89e-269 XK27_05220 - - S - - - AI-2E family transporter
NIEGOPEA_01777 8e-136 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NIEGOPEA_01778 1.96e-98 - - - S - - - Protein of unknown function (DUF1149)
NIEGOPEA_01779 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NIEGOPEA_01780 4.09e-291 ymfF - - S - - - Peptidase M16 inactive domain protein
NIEGOPEA_01781 4.65e-296 ymfH - - S - - - Peptidase M16
NIEGOPEA_01782 1.05e-166 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
NIEGOPEA_01783 1.48e-178 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
NIEGOPEA_01784 7.62e-126 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NIEGOPEA_01785 2.99e-248 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NIEGOPEA_01786 0.0 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
NIEGOPEA_01787 9.48e-262 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
NIEGOPEA_01788 0.0 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_01789 1.06e-150 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
NIEGOPEA_01790 9.86e-262 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
NIEGOPEA_01791 1.84e-162 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
NIEGOPEA_01792 3.97e-125 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NIEGOPEA_01793 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NIEGOPEA_01794 3.56e-235 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NIEGOPEA_01795 3.73e-40 - - - - - - - -
NIEGOPEA_01796 6.07e-225 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NIEGOPEA_01797 2.16e-202 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NIEGOPEA_01798 1.29e-236 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
NIEGOPEA_01799 1.05e-221 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NIEGOPEA_01800 7.28e-243 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NIEGOPEA_01801 4.7e-237 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
NIEGOPEA_01802 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
NIEGOPEA_01803 1.36e-241 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NIEGOPEA_01804 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
NIEGOPEA_01805 0.0 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
NIEGOPEA_01806 1.36e-286 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NIEGOPEA_01807 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
NIEGOPEA_01808 1.94e-246 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
NIEGOPEA_01809 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NIEGOPEA_01810 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NIEGOPEA_01811 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NIEGOPEA_01812 2.04e-117 - - - S - - - Short repeat of unknown function (DUF308)
NIEGOPEA_01813 7.82e-316 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEGOPEA_01814 1.58e-206 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
NIEGOPEA_01815 1.26e-246 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
NIEGOPEA_01816 2.02e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
NIEGOPEA_01817 3.74e-130 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NIEGOPEA_01818 0.0 ycaM - - E - - - amino acid
NIEGOPEA_01820 3.72e-238 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
NIEGOPEA_01821 4.74e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NIEGOPEA_01822 7.02e-287 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
NIEGOPEA_01823 5.9e-182 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NIEGOPEA_01824 1.18e-311 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NIEGOPEA_01825 7.52e-40 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
NIEGOPEA_01826 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NIEGOPEA_01827 1.46e-101 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NIEGOPEA_01828 6.82e-139 - - - K ko:K06977 - ko00000 acetyltransferase
NIEGOPEA_01829 2.21e-110 - - - - - - - -
NIEGOPEA_01830 7.24e-49 - - - - - - - -
NIEGOPEA_01831 6.67e-202 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
NIEGOPEA_01832 1.02e-172 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NIEGOPEA_01833 4.47e-230 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
NIEGOPEA_01834 1.75e-110 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
NIEGOPEA_01835 6.4e-129 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NIEGOPEA_01836 1.12e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
NIEGOPEA_01837 2.41e-260 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NIEGOPEA_01838 2.51e-172 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NIEGOPEA_01839 1.08e-175 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NIEGOPEA_01840 8.14e-265 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NIEGOPEA_01841 6.38e-197 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NIEGOPEA_01842 1.33e-225 ybbR - - S - - - YbbR-like protein
NIEGOPEA_01843 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NIEGOPEA_01844 2.8e-190 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NIEGOPEA_01845 3.02e-88 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NIEGOPEA_01846 8.65e-81 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NIEGOPEA_01847 1.42e-255 - - - S - - - Putative adhesin
NIEGOPEA_01848 6.94e-148 - - - - - - - -
NIEGOPEA_01849 5.93e-190 - - - S - - - Alpha/beta hydrolase family
NIEGOPEA_01850 8.84e-211 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NIEGOPEA_01851 1.75e-275 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NIEGOPEA_01852 3.59e-123 - - - S - - - VanZ like family
NIEGOPEA_01853 6.1e-171 yebC - - K - - - Transcriptional regulatory protein
NIEGOPEA_01854 6.35e-230 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
NIEGOPEA_01855 8.54e-223 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
NIEGOPEA_01856 9.23e-55 comGC - - U ko:K02245,ko:K02456 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 Required for transformation and DNA binding
NIEGOPEA_01857 3.97e-77 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
NIEGOPEA_01859 8.81e-114 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
NIEGOPEA_01860 4.19e-239 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
NIEGOPEA_01861 9.62e-289 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NIEGOPEA_01863 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Levansucrase/Invertase
NIEGOPEA_01864 1.36e-131 - - - M - - - Protein of unknown function (DUF3737)
NIEGOPEA_01865 1.35e-281 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
NIEGOPEA_01866 1.21e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)