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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HEGBPLAD_00001	7.47e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HEGBPLAD_00002	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEGBPLAD_00003	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HEGBPLAD_00004	7.48e-236	-	-	-	GM	-	-	-	Male sterility protein
HEGBPLAD_00005	2.1e-99	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HEGBPLAD_00006	5.37e-100	-	-	-	M	-	-	-	LysM domain
HEGBPLAD_00007	1.28e-51	-	-	-	-	-	-	-	-
HEGBPLAD_00008	9.28e-58	-	-	-	-	-	-	-	-
HEGBPLAD_00009	1.27e-109	-	-	-	K	-	-	-	MarR family
HEGBPLAD_00010	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
HEGBPLAD_00011	0.0	inlJ	-	-	M	-	-	-	MucBP domain
HEGBPLAD_00012	6.58e-24	-	-	-	-	-	-	-	-
HEGBPLAD_00013	2.19e-180	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HEGBPLAD_00014	3.66e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HEGBPLAD_00015	7.78e-201	degV1	-	-	S	-	-	-	DegV family
HEGBPLAD_00016	8.29e-80	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
HEGBPLAD_00017	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HEGBPLAD_00018	2.76e-141	sip3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HEGBPLAD_00019	1.12e-51	-	-	-	-	-	-	-	-
HEGBPLAD_00020	4.95e-235	-	-	-	S	-	-	-	Phage tail protein
HEGBPLAD_00021	0.0	-	-	-	S	-	-	-	Phage minor structural protein
HEGBPLAD_00022	4.56e-179	-	-	-	-	-	-	-	-
HEGBPLAD_00025	3.36e-91	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HEGBPLAD_00026	1.15e-314	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HEGBPLAD_00027	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HEGBPLAD_00028	1.03e-35	-	-	-	S	-	-	-	Belongs to the LOG family
HEGBPLAD_00029	7.12e-256	glmS2	-	-	M	-	-	-	SIS domain
HEGBPLAD_00032	0.0	-	-	-	C	-	-	-	FMN_bind
HEGBPLAD_00033	3.77e-218	-	-	-	K	-	-	-	Transcriptional regulator
HEGBPLAD_00034	7.78e-15	-	-	-	K	-	-	-	Helix-turn-helix domain
HEGBPLAD_00035	1.2e-97	-	-	-	K	-	-	-	Helix-turn-helix domain
HEGBPLAD_00036	7.15e-178	-	-	-	K	-	-	-	sequence-specific DNA binding
HEGBPLAD_00037	4.32e-50	-	-	-	S	-	-	-	AAA domain
HEGBPLAD_00038	2.12e-45	-	-	-	S	-	-	-	AAA domain
HEGBPLAD_00039	9.18e-22	-	-	-	S	-	-	-	Bacteriophage holin
HEGBPLAD_00040	3.93e-99	-	-	-	T	-	-	-	Universal stress protein family
HEGBPLAD_00041	7.41e-312	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEGBPLAD_00042	5.54e-210	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HEGBPLAD_00044	7.62e-97	-	-	-	-	-	-	-	-
HEGBPLAD_00045	2.68e-135	-	-	-	-	-	-	-	-
HEGBPLAD_00046	4.91e-285	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HEGBPLAD_00047	4.1e-87	lysM	-	-	M	-	-	-	LysM domain
HEGBPLAD_00048	0.0	-	-	-	E	-	-	-	Amino Acid
HEGBPLAD_00049	2.03e-184	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEGBPLAD_00050	6.82e-158	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HEGBPLAD_00051	2.34e-265	mccF	-	-	V	-	-	-	LD-carboxypeptidase
HEGBPLAD_00052	9.19e-99	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HEGBPLAD_00053	3.94e-308	-	-	-	M	ko:K07273	-	ko00000	hydrolase, family 25
HEGBPLAD_00054	2.48e-196	-	-	-	V	-	-	-	LD-carboxypeptidase
HEGBPLAD_00055	9.51e-135	-	-	-	-	-	-	-	-
HEGBPLAD_00056	0.0	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
HEGBPLAD_00057	1.3e-131	-	-	-	-	-	-	-	-
HEGBPLAD_00058	6.04e-51	-	-	-	-	-	-	-	-
HEGBPLAD_00059	7.19e-261	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HEGBPLAD_00060	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HEGBPLAD_00061	1.91e-66	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HEGBPLAD_00062	8.27e-130	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HEGBPLAD_00063	2.99e-109	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HEGBPLAD_00064	8.61e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HEGBPLAD_00065	2.6e-155	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HEGBPLAD_00066	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HEGBPLAD_00067	1.05e-210	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HEGBPLAD_00068	1.36e-284	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HEGBPLAD_00069	2.16e-230	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HEGBPLAD_00070	1.18e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HEGBPLAD_00071	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HEGBPLAD_00072	4.06e-20	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HEGBPLAD_00073	1.77e-137	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HEGBPLAD_00074	2.55e-57	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HEGBPLAD_00075	1.24e-198	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HEGBPLAD_00076	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEGBPLAD_00077	7.67e-200	-	-	-	S	-	-	-	Tetratricopeptide repeat
HEGBPLAD_00078	4.38e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HEGBPLAD_00079	5.32e-287	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HEGBPLAD_00080	3.18e-299	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HEGBPLAD_00081	9.6e-143	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HEGBPLAD_00082	1.3e-65	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HEGBPLAD_00083	6.47e-95	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HEGBPLAD_00084	5.12e-31	-	-	-	-	-	-	-	-
HEGBPLAD_00085	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HEGBPLAD_00086	9.36e-172	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HEGBPLAD_00087	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HEGBPLAD_00088	2.42e-107	epsB	-	-	M	-	-	-	biosynthesis protein
HEGBPLAD_00089	2.45e-32	epsB	-	-	M	-	-	-	biosynthesis protein
HEGBPLAD_00090	4.97e-157	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HEGBPLAD_00091	4.08e-104	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HEGBPLAD_00092	3.25e-70	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HEGBPLAD_00093	5.94e-189	cps4D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HEGBPLAD_00094	2.33e-164	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
HEGBPLAD_00095	1.28e-255	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
HEGBPLAD_00096	1.5e-232	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
HEGBPLAD_00097	5.01e-293	-	-	-	-	-	-	-	-
HEGBPLAD_00098	4.22e-204	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
HEGBPLAD_00099	0.0	cps4J	-	-	S	-	-	-	MatE
HEGBPLAD_00100	0.0	-	3.1.4.53	-	S	ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HEGBPLAD_00101	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HEGBPLAD_00102	7.34e-219	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HEGBPLAD_00103	6.09e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HEGBPLAD_00104	7.38e-310	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HEGBPLAD_00105	6.62e-62	-	-	-	-	-	-	-	-
HEGBPLAD_00106	9.74e-227	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HEGBPLAD_00107	1.37e-177	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HEGBPLAD_00108	1.84e-67	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HEGBPLAD_00109	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HEGBPLAD_00110	1.52e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HEGBPLAD_00111	1.25e-129	-	-	-	K	-	-	-	Helix-turn-helix domain
HEGBPLAD_00112	6.46e-267	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HEGBPLAD_00113	3.32e-74	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
HEGBPLAD_00114	1.02e-183	-	-	-	Q	-	-	-	Methyltransferase
HEGBPLAD_00115	1.75e-43	-	-	-	-	-	-	-	-
HEGBPLAD_00116	1.55e-75	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HEGBPLAD_00120	2.35e-106	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEGBPLAD_00121	1.08e-60	-	-	-	-	-	-	-	-
HEGBPLAD_00122	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HEGBPLAD_00123	4.37e-241	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEGBPLAD_00124	4.85e-186	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
HEGBPLAD_00125	1.75e-76	-	-	-	L	-	-	-	DnaD domain protein
HEGBPLAD_00126	1.84e-170	-	-	-	S	-	-	-	Putative HNHc nuclease
HEGBPLAD_00127	1.89e-89	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HEGBPLAD_00128	4.45e-133	-	-	-	S	-	-	-	ERF superfamily
HEGBPLAD_00129	1.73e-187	-	-	-	S	-	-	-	Protein of unknown function (DUF1351)
HEGBPLAD_00130	1.76e-281	-	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
HEGBPLAD_00131	2.8e-161	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HEGBPLAD_00132	7.15e-38	-	-	-	-	-	-	-	-
HEGBPLAD_00133	9.72e-200	-	-	-	M	-	-	-	Prophage endopeptidase tail
HEGBPLAD_00134	6.06e-226	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HEGBPLAD_00135	1.23e-116	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
HEGBPLAD_00139	1.27e-216	-	-	-	S	-	-	-	Phage portal protein
HEGBPLAD_00140	4.9e-161	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HEGBPLAD_00141	1.33e-250	-	-	-	S	-	-	-	Phage capsid family
HEGBPLAD_00142	6.59e-65	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HEGBPLAD_00143	2.84e-75	-	-	-	S	-	-	-	Phage head-tail joining protein
HEGBPLAD_00144	1.59e-86	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HEGBPLAD_00145	3.26e-59	-	-	-	L	-	-	-	Integrase
HEGBPLAD_00146	1.11e-59	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HEGBPLAD_00147	8.69e-76	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
HEGBPLAD_00148	4.42e-289	-	-	-	G	-	-	-	Polysaccharide deacetylase
HEGBPLAD_00149	2.06e-89	-	-	-	S	ko:K06994	-	ko00000	MMPL family
HEGBPLAD_00150	2.1e-45	-	-	-	-	-	-	-	-
HEGBPLAD_00153	4.97e-127	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
HEGBPLAD_00154	1.27e-94	-	-	-	L	-	-	-	Initiator Replication protein
HEGBPLAD_00155	2.16e-27	-	-	-	L	-	-	-	Initiator Replication protein
HEGBPLAD_00156	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HEGBPLAD_00157	1.62e-158	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HEGBPLAD_00158	4.04e-67	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HEGBPLAD_00159	9.43e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HEGBPLAD_00160	9.11e-251	mob	-	-	D	-	-	-	Plasmid recombination enzyme
HEGBPLAD_00161	3.68e-167	-	-	-	L	-	-	-	Replication protein
HEGBPLAD_00163	4.54e-32	-	-	-	-	-	-	-	-
HEGBPLAD_00164	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
HEGBPLAD_00165	4.75e-142	-	-	-	-	-	-	-	-
HEGBPLAD_00166	3.43e-145	-	-	-	-	-	-	-	-
HEGBPLAD_00168	6.09e-209	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HEGBPLAD_00169	1.64e-140	-	-	-	S	-	-	-	Cell surface protein
HEGBPLAD_00170	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HEGBPLAD_00171	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HEGBPLAD_00172	7.52e-170	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HEGBPLAD_00173	1.27e-157	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEGBPLAD_00174	3.74e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HEGBPLAD_00175	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HEGBPLAD_00176	8.19e-267	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HEGBPLAD_00177	3.15e-50	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HEGBPLAD_00178	8.44e-262	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HEGBPLAD_00179	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEGBPLAD_00180	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEGBPLAD_00181	5.95e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HEGBPLAD_00182	4.81e-108	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HEGBPLAD_00183	2.69e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HEGBPLAD_00184	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HEGBPLAD_00185	3.44e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HEGBPLAD_00186	8.77e-317	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HEGBPLAD_00187	4.96e-289	yttB	-	-	EGP	-	-	-	Major Facilitator
HEGBPLAD_00188	5.21e-183	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HEGBPLAD_00189	8.93e-290	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HEGBPLAD_00190	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HEGBPLAD_00192	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HEGBPLAD_00193	6.65e-282	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HEGBPLAD_00194	4.07e-268	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HEGBPLAD_00195	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HEGBPLAD_00196	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HEGBPLAD_00197	4.32e-102	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HEGBPLAD_00198	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HEGBPLAD_00200	1.19e-183	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HEGBPLAD_00201	1.28e-153	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HEGBPLAD_00202	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
HEGBPLAD_00203	8.99e-185	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
HEGBPLAD_00204	2.54e-43	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
HEGBPLAD_00205	2.65e-47	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
HEGBPLAD_00206	4.37e-43	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein domain
HEGBPLAD_00207	2.54e-50	-	-	-	-	-	-	-	-
HEGBPLAD_00209	2.22e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HEGBPLAD_00210	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEGBPLAD_00211	5.04e-313	yycH	-	-	S	-	-	-	YycH protein
HEGBPLAD_00212	1.18e-193	yycI	-	-	S	-	-	-	YycH protein
HEGBPLAD_00213	1.71e-200	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HEGBPLAD_00214	2.48e-252	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HEGBPLAD_00215	6.08e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HEGBPLAD_00216	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HEGBPLAD_00217	1.69e-55	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HEGBPLAD_00218	1.57e-45	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HEGBPLAD_00219	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HEGBPLAD_00220	2.08e-46	-	-	-	S	-	-	-	Haemolysin XhlA
HEGBPLAD_00221	1.96e-204	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HEGBPLAD_00222	1.56e-29	-	-	-	-	-	-	-	-
HEGBPLAD_00223	4.76e-27	-	-	-	-	-	-	-	-
HEGBPLAD_00224	1.58e-97	-	-	-	-	-	-	-	-
HEGBPLAD_00225	8.77e-106	-	-	-	L	-	-	-	C-5 cytosine-specific DNA methylase
HEGBPLAD_00227	2.1e-44	-	-	-	S	-	-	-	YopX protein
HEGBPLAD_00228	6.46e-47	-	-	-	-	-	-	-	-
HEGBPLAD_00230	4.53e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF1056)
HEGBPLAD_00231	0.0	-	-	-	S	-	-	-	Phage Terminase
HEGBPLAD_00232	2.72e-102	-	-	-	L	-	-	-	Phage terminase, small subunit
HEGBPLAD_00233	4.21e-131	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HEGBPLAD_00234	2.31e-197	cylA	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HEGBPLAD_00235	4e-180	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
HEGBPLAD_00236	6.33e-63	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HEGBPLAD_00237	3.25e-181	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HEGBPLAD_00238	6.53e-58	-	-	-	-	-	-	-	-
HEGBPLAD_00239	2.61e-111	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HEGBPLAD_00240	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
HEGBPLAD_00243	6.96e-116	-	-	-	L	-	-	-	HNH nucleases
HEGBPLAD_00246	6.89e-27	-	-	-	-	-	-	-	-
HEGBPLAD_00248	3.72e-92	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	site-specific DNA-methyltransferase (adenine-specific) activity
HEGBPLAD_00249	9.73e-16	-	-	-	-	-	-	-	-
HEGBPLAD_00251	3.18e-77	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEGBPLAD_00252	4.65e-73	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEGBPLAD_00253	0.0	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
HEGBPLAD_00254	5.02e-149	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HEGBPLAD_00255	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HEGBPLAD_00256	1.43e-131	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC transporter permease
HEGBPLAD_00257	6.07e-117	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HEGBPLAD_00258	8.79e-201	dkgB	-	-	S	-	-	-	reductase
HEGBPLAD_00259	3.68e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HEGBPLAD_00260	6.95e-91	-	-	-	-	-	-	-	-
HEGBPLAD_00261	5.24e-169	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HEGBPLAD_00263	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HEGBPLAD_00264	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HEGBPLAD_00265	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
HEGBPLAD_00266	5.33e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEGBPLAD_00267	2.61e-282	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HEGBPLAD_00268	5.25e-106	-	-	-	-	-	-	-	-
HEGBPLAD_00269	4.81e-76	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HEGBPLAD_00270	5.92e-67	-	-	-	-	-	-	-	-
HEGBPLAD_00271	4.1e-124	-	-	-	-	-	-	-	-
HEGBPLAD_00272	2.98e-90	-	-	-	-	-	-	-	-
HEGBPLAD_00273	1.2e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HEGBPLAD_00274	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HEGBPLAD_00275	2.21e-127	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
HEGBPLAD_00276	5.19e-157	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
HEGBPLAD_00277	4.75e-290	pts3C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEGBPLAD_00278	6.14e-53	-	-	-	-	-	-	-	-
HEGBPLAD_00279	6.23e-268	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HEGBPLAD_00280	1.73e-269	dho	3.5.2.3	-	S	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase family
HEGBPLAD_00281	8.38e-258	selA	2.9.1.1	-	H	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	L-seryl-tRNA selenium transferase
HEGBPLAD_00282	7.08e-166	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
HEGBPLAD_00283	8.21e-245	-	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
HEGBPLAD_00284	3.53e-123	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
HEGBPLAD_00285	3.34e-267	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HEGBPLAD_00286	7.54e-211	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HEGBPLAD_00287	1.93e-202	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HEGBPLAD_00288	1.27e-181	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HEGBPLAD_00289	4.37e-57	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
HEGBPLAD_00290	2.21e-56	-	-	-	-	-	-	-	-
HEGBPLAD_00291	6.84e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HEGBPLAD_00292	5.37e-185	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HEGBPLAD_00293	9.67e-185	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HEGBPLAD_00294	4.35e-116	pts4ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEGBPLAD_00295	0.0	pts4ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEGBPLAD_00296	0.0	pts5ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HEGBPLAD_00297	2.6e-185	-	-	-	-	-	-	-	-
HEGBPLAD_00298	3.37e-129	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HEGBPLAD_00299	2.16e-89	-	-	-	-	-	-	-	-
HEGBPLAD_00300	5.15e-95	ywnA	-	-	K	-	-	-	Transcriptional regulator
HEGBPLAD_00301	5.2e-156	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HEGBPLAD_00302	1.64e-300	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HEGBPLAD_00303	2.58e-148	-	-	-	-	-	-	-	-
HEGBPLAD_00304	4.16e-57	-	-	-	-	-	-	-	-
HEGBPLAD_00305	1.55e-55	-	-	-	-	-	-	-	-
HEGBPLAD_00306	0.0	ydiC	-	-	EGP	-	-	-	Major Facilitator
HEGBPLAD_00307	1.31e-68	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HEGBPLAD_00308	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
HEGBPLAD_00309	1.43e-271	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HEGBPLAD_00312	7.42e-99	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HEGBPLAD_00314	6.16e-66	-	-	-	-	-	-	-	-
HEGBPLAD_00315	5.02e-158	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HEGBPLAD_00316	2.66e-290	-	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
HEGBPLAD_00317	1.71e-247	-	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
HEGBPLAD_00318	3.2e-76	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HEGBPLAD_00319	7.9e-54	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HEGBPLAD_00320	4.3e-52	-	-	-	S	-	-	-	Beta protein
HEGBPLAD_00321	0.0	cidC	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HEGBPLAD_00322	7.39e-224	-	-	-	L	ko:K07482	-	ko00000	Integrase core domain
HEGBPLAD_00323	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HEGBPLAD_00324	1.5e-85	-	-	-	L	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
HEGBPLAD_00325	3.82e-188	-	-	-	KT	-	-	-	helix_turn_helix, mercury resistance
HEGBPLAD_00326	2.4e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HEGBPLAD_00327	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HEGBPLAD_00328	7.73e-179	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
HEGBPLAD_00329	1.76e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HEGBPLAD_00330	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HEGBPLAD_00331	6.64e-167	-	-	-	-	-	-	-	-
HEGBPLAD_00332	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HEGBPLAD_00333	2.39e-177	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HEGBPLAD_00334	3.74e-285	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HEGBPLAD_00335	2.02e-245	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HEGBPLAD_00336	1.92e-240	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HEGBPLAD_00337	6.6e-311	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
HEGBPLAD_00339	5.11e-133	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HEGBPLAD_00340	1.55e-225	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEGBPLAD_00341	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HEGBPLAD_00342	1.21e-215	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HEGBPLAD_00343	4.56e-243	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HEGBPLAD_00344	1.71e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HEGBPLAD_00345	8.62e-114	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HEGBPLAD_00346	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HEGBPLAD_00347	8.76e-301	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HEGBPLAD_00348	2.21e-113	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HEGBPLAD_00349	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HEGBPLAD_00350	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HEGBPLAD_00351	3.17e-150	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HEGBPLAD_00352	1.53e-267	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
HEGBPLAD_00353	6.33e-133	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HEGBPLAD_00354	0.0	nox2	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HEGBPLAD_00355	9.78e-169	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HEGBPLAD_00356	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HEGBPLAD_00357	1.07e-98	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HEGBPLAD_00358	5.55e-24	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HEGBPLAD_00359	4.33e-105	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HEGBPLAD_00360	8.65e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HEGBPLAD_00361	3.75e-170	-	-	-	T	-	-	-	diguanylate cyclase activity
HEGBPLAD_00362	3e-121	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
HEGBPLAD_00363	1.81e-154	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
HEGBPLAD_00364	2.97e-70	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
HEGBPLAD_00365	9.36e-55	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
HEGBPLAD_00366	8.73e-191	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
HEGBPLAD_00367	9.69e-256	-	-	-	S	-	-	-	Protein conserved in bacteria
HEGBPLAD_00368	5.68e-195	-	-	-	-	-	-	-	-
HEGBPLAD_00369	1.78e-78	-	-	-	-	-	-	-	-
HEGBPLAD_00370	3.52e-204	ydaJ	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HEGBPLAD_00371	5.45e-203	nox	-	-	C	-	-	-	NADH oxidase
HEGBPLAD_00372	3.06e-131	-	-	-	S	-	-	-	Phage tail tube protein
HEGBPLAD_00373	2.73e-75	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
HEGBPLAD_00375	1.18e-144	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HEGBPLAD_00376	5.21e-98	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HEGBPLAD_00377	1.82e-132	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEGBPLAD_00378	3.45e-31	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEGBPLAD_00379	1.72e-158	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HEGBPLAD_00381	5.18e-80	-	-	-	S	-	-	-	DNA binding
HEGBPLAD_00384	1.38e-275	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HEGBPLAD_00385	2.6e-168	-	-	-	L	-	-	-	Helix-turn-helix domain
HEGBPLAD_00386	1.96e-169	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HEGBPLAD_00387	3.62e-22	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
HEGBPLAD_00388	3.84e-73	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
HEGBPLAD_00389	1.03e-101	gpG	-	-	-	-	-	-	-
HEGBPLAD_00390	3.24e-77	dinG	2.7.7.7, 3.6.4.12	-	L	ko:K02342,ko:K03722,ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA-directed DNA polymerase activity
HEGBPLAD_00391	7.27e-289	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HEGBPLAD_00392	0.000204	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HEGBPLAD_00394	8.27e-15	-	-	-	-	-	-	-	-
HEGBPLAD_00395	6.2e-39	-	-	-	-	-	-	-	-
HEGBPLAD_00396	4.68e-191	-	-	-	L	-	-	-	DNA replication protein
HEGBPLAD_00397	0.0	-	-	-	S	-	-	-	Virulence-associated protein E
HEGBPLAD_00398	3.97e-112	-	-	-	-	-	-	-	-
HEGBPLAD_00399	1.47e-33	-	-	-	-	-	-	-	-
HEGBPLAD_00400	6.06e-67	-	-	-	S	-	-	-	Head-tail joining protein
HEGBPLAD_00401	1.82e-107	-	-	-	L	-	-	-	overlaps another CDS with the same product name
HEGBPLAD_00402	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
HEGBPLAD_00403	9.09e-258	-	-	-	S	-	-	-	Phage portal protein
HEGBPLAD_00404	3.01e-264	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
HEGBPLAD_00405	3.39e-55	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HEGBPLAD_00406	3.85e-76	-	-	-	-	-	-	-	-
HEGBPLAD_00409	1.91e-38	-	-	-	-	-	-	-	-
HEGBPLAD_00411	1.56e-277	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HEGBPLAD_00415	9.51e-48	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HEGBPLAD_00417	2.72e-46	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HEGBPLAD_00419	7.08e-26	-	-	-	S	-	-	-	protein disulfide oxidoreductase activity
HEGBPLAD_00422	1.55e-12	-	-	-	S	-	-	-	Hypothetical protein (DUF2513)
HEGBPLAD_00423	1.19e-24	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HEGBPLAD_00424	2.62e-08	-	-	-	K	-	-	-	Transcriptional regulator, XRE family
HEGBPLAD_00427	1.56e-70	-	-	-	-	-	-	-	-
HEGBPLAD_00428	7.5e-111	-	-	-	-	-	-	-	-
HEGBPLAD_00429	2.36e-30	-	-	-	S	ko:K09946	-	ko00000	Domain of unknown function (DUF1508)
HEGBPLAD_00432	7.79e-106	-	-	-	-	-	-	-	-
HEGBPLAD_00433	3.75e-81	-	-	-	S	-	-	-	ERF superfamily
HEGBPLAD_00434	1.52e-57	-	-	-	S	-	-	-	Single-strand binding protein family
HEGBPLAD_00435	4.3e-206	-	-	-	L	-	-	-	DnaD domain protein
HEGBPLAD_00436	1.09e-65	-	-	-	-	-	-	-	-
HEGBPLAD_00437	1.83e-77	-	-	-	K	ko:K07741	-	ko00000	AntA/AntB antirepressor
HEGBPLAD_00438	5.89e-109	-	-	-	-	-	-	-	-
HEGBPLAD_00439	1.91e-85	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HEGBPLAD_00441	4.5e-16	-	-	-	S	-	-	-	YopX protein
HEGBPLAD_00442	2.24e-106	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
HEGBPLAD_00445	1.64e-84	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
HEGBPLAD_00446	0.0	-	-	-	S	ko:K06909	-	ko00000	Phage terminase, large subunit
HEGBPLAD_00447	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HEGBPLAD_00448	7.01e-217	-	-	-	S	-	-	-	Phage Mu protein F like protein
HEGBPLAD_00449	2.54e-108	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
HEGBPLAD_00450	1.45e-239	gpG	-	-	-	-	-	-	-
HEGBPLAD_00451	5.59e-78	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HEGBPLAD_00452	4.49e-66	-	-	-	-	-	-	-	-
HEGBPLAD_00453	2.89e-124	-	-	-	-	-	-	-	-
HEGBPLAD_00454	2.19e-78	-	-	-	-	-	-	-	-
HEGBPLAD_00455	2e-121	-	-	-	-	-	-	-	-
HEGBPLAD_00456	4.6e-108	-	-	-	S	-	-	-	Phage tail assembly chaperone protein, TAC
HEGBPLAD_00458	0.0	-	-	-	D	-	-	-	domain protein
HEGBPLAD_00459	6.56e-171	-	-	-	S	-	-	-	phage tail
HEGBPLAD_00460	7.3e-56	cps2I	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HEGBPLAD_00461	3.07e-284	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HEGBPLAD_00462	5.13e-73	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HEGBPLAD_00463	1.65e-112	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
HEGBPLAD_00464	9.4e-122	-	-	-	L	-	-	-	4.5 Transposon and IS
HEGBPLAD_00465	1.15e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase
HEGBPLAD_00466	4.68e-198	is18	-	-	L	-	-	-	Integrase core domain
HEGBPLAD_00468	1.04e-42	-	-	-	L	-	-	-	Integrase
HEGBPLAD_00469	1.4e-79	-	-	-	L	-	-	-	Integrase
HEGBPLAD_00470	2.55e-74	-	-	-	-	-	-	-	-
HEGBPLAD_00472	3.19e-194	-	-	-	S	-	-	-	FMN_bind
HEGBPLAD_00473	2.96e-285	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HEGBPLAD_00474	1.98e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEGBPLAD_00475	2.01e-211	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEGBPLAD_00476	1.38e-183	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEGBPLAD_00477	2.29e-191	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HEGBPLAD_00478	4.58e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HEGBPLAD_00479	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HEGBPLAD_00480	9.94e-209	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HEGBPLAD_00481	3.48e-212	-	-	-	S	-	-	-	Membrane
HEGBPLAD_00482	3.7e-259	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HEGBPLAD_00483	0.0	tkt2	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HEGBPLAD_00484	1.42e-212	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HEGBPLAD_00485	1.34e-234	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	DAHP synthetase I family
HEGBPLAD_00486	1.05e-252	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HEGBPLAD_00488	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HEGBPLAD_00489	3.05e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HEGBPLAD_00490	1.65e-146	-	4.2.1.2, 4.2.1.32	-	C	ko:K01676,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
HEGBPLAD_00491	2.48e-224	ttdA	4.2.1.32	-	C	ko:K03779	ko00630,map00630	ko00000,ko00001,ko01000	Fumarate hydratase (Fumerase)
HEGBPLAD_00492	8.99e-254	-	-	-	K	-	-	-	Helix-turn-helix domain
HEGBPLAD_00493	3.16e-196	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HEGBPLAD_00494	5.85e-170	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HEGBPLAD_00495	3.54e-180	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HEGBPLAD_00496	5.19e-223	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HEGBPLAD_00497	1.18e-66	-	-	-	-	-	-	-	-
HEGBPLAD_00498	2.53e-212	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HEGBPLAD_00499	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HEGBPLAD_00500	4.82e-227	citR	-	-	K	-	-	-	sugar-binding domain protein
HEGBPLAD_00501	1.84e-262	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
HEGBPLAD_00502	8.79e-241	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HEGBPLAD_00503	7.1e-58	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
HEGBPLAD_00504	3.71e-207	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
HEGBPLAD_00505	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
HEGBPLAD_00507	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HEGBPLAD_00508	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HEGBPLAD_00509	1.98e-122	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HEGBPLAD_00510	1.52e-205	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
HEGBPLAD_00511	2.15e-189	mleR	-	-	K	-	-	-	LysR family
HEGBPLAD_00512	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HEGBPLAD_00513	3.21e-188	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
HEGBPLAD_00514	5.81e-88	-	-	-	L	-	-	-	Transposase
HEGBPLAD_00515	5.8e-46	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HEGBPLAD_00516	8.77e-77	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HEGBPLAD_00517	1.69e-107	-	-	-	L	-	-	-	Transposase DDE domain
HEGBPLAD_00518	8.82e-32	-	-	-	-	-	-	-	-
HEGBPLAD_00519	1.93e-31	plnF	-	-	-	-	-	-	-
HEGBPLAD_00520	3.22e-165	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HEGBPLAD_00522	1.01e-138	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HEGBPLAD_00523	6.31e-51	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HEGBPLAD_00525	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HEGBPLAD_00526	1.56e-46	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HEGBPLAD_00527	4.76e-290	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HEGBPLAD_00528	9.56e-278	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HEGBPLAD_00529	1.46e-239	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HEGBPLAD_00530	4.81e-253	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HEGBPLAD_00531	9.51e-284	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HEGBPLAD_00532	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HEGBPLAD_00533	1.24e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HEGBPLAD_00534	4.61e-40	-	-	-	-	-	-	-	-
HEGBPLAD_00535	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HEGBPLAD_00536	1.45e-131	-	-	-	L	-	-	-	Integrase
HEGBPLAD_00537	3.4e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HEGBPLAD_00538	1.9e-229	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEGBPLAD_00539	1.69e-258	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEGBPLAD_00540	3.59e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEGBPLAD_00541	3.44e-210	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEGBPLAD_00542	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HEGBPLAD_00543	3.85e-76	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
HEGBPLAD_00544	1.01e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HEGBPLAD_00545	4.35e-205	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HEGBPLAD_00546	1.01e-250	-	-	-	M	-	-	-	MucBP domain
HEGBPLAD_00547	0.0	-	-	-	-	-	-	-	-
HEGBPLAD_00548	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HEGBPLAD_00549	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HEGBPLAD_00550	1e-217	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HEGBPLAD_00551	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HEGBPLAD_00552	1.59e-289	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HEGBPLAD_00553	6.04e-94	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HEGBPLAD_00554	4.61e-257	yueF	-	-	S	-	-	-	AI-2E family transporter
HEGBPLAD_00555	7.3e-216	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HEGBPLAD_00556	7.17e-39	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HEGBPLAD_00557	3.97e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
HEGBPLAD_00558	4.09e-172	lytE	-	-	M	-	-	-	NlpC/P60 family
HEGBPLAD_00559	6.62e-138	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HEGBPLAD_00560	1.67e-180	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HEGBPLAD_00561	1.9e-168	-	-	-	-	-	-	-	-
HEGBPLAD_00562	1.68e-131	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HEGBPLAD_00563	1.4e-36	-	-	-	-	-	-	-	-
HEGBPLAD_00564	8.63e-25	-	-	-	-	-	-	-	-
HEGBPLAD_00565	1.04e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HEGBPLAD_00566	1.06e-68	-	-	-	-	-	-	-	-
HEGBPLAD_00567	3.46e-148	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HEGBPLAD_00568	1.18e-114	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HEGBPLAD_00571	1.09e-82	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
HEGBPLAD_00572	1e-54	-	-	-	V	-	-	-	VanZ like family
HEGBPLAD_00573	3.62e-249	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HEGBPLAD_00574	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HEGBPLAD_00575	4.66e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HEGBPLAD_00576	3.95e-166	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HEGBPLAD_00577	2.98e-236	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HEGBPLAD_00578	3.8e-176	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HEGBPLAD_00579	5.35e-177	phnE2	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter permease
HEGBPLAD_00580	3.33e-184	phnE1	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HEGBPLAD_00581	1.14e-186	phnX	3.11.1.1	-	E	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the HAD-like hydrolase superfamily. PhnX family
HEGBPLAD_00582	2e-265	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HEGBPLAD_00583	4.06e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HEGBPLAD_00584	5.27e-190	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HEGBPLAD_00585	4.39e-212	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HEGBPLAD_00586	8.46e-77	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HEGBPLAD_00587	2.33e-239	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HEGBPLAD_00588	1.39e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HEGBPLAD_00589	2.22e-153	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HEGBPLAD_00590	1.01e-51	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HEGBPLAD_00591	6.22e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HEGBPLAD_00592	2.05e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HEGBPLAD_00593	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEGBPLAD_00594	7.57e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HEGBPLAD_00595	6.7e-141	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HEGBPLAD_00596	5.92e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HEGBPLAD_00597	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEGBPLAD_00598	2.47e-253	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEGBPLAD_00599	5.82e-141	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HEGBPLAD_00600	3.14e-51	-	-	-	K	-	-	-	Helix-turn-helix domain
HEGBPLAD_00601	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HEGBPLAD_00602	8.38e-87	-	-	-	L	-	-	-	nuclease
HEGBPLAD_00603	3.02e-228	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HEGBPLAD_00604	2.76e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HEGBPLAD_00605	3.72e-105	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HEGBPLAD_00606	2.69e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HEGBPLAD_00607	9.76e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HEGBPLAD_00608	6.63e-201	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HEGBPLAD_00609	1.89e-128	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HEGBPLAD_00610	1e-39	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HEGBPLAD_00611	4.55e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HEGBPLAD_00612	6.5e-130	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
HEGBPLAD_00613	6.12e-127	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
HEGBPLAD_00614	1.74e-176	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEGBPLAD_00615	1.35e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HEGBPLAD_00616	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HEGBPLAD_00617	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HEGBPLAD_00618	5.72e-264	yacL	-	-	S	-	-	-	domain protein
HEGBPLAD_00619	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HEGBPLAD_00622	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HEGBPLAD_00623	1.5e-194	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HEGBPLAD_00627	1.17e-63	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
HEGBPLAD_00628	1.38e-71	-	-	-	S	-	-	-	Cupin domain
HEGBPLAD_00629	1.31e-213	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
HEGBPLAD_00630	1.88e-88	ysdE	-	-	P	-	-	-	Citrate transporter
HEGBPLAD_00631	4.03e-106	ysdE	-	-	P	-	-	-	Citrate transporter
HEGBPLAD_00632	3.92e-66	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HEGBPLAD_00633	5.35e-175	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEGBPLAD_00634	2.92e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HEGBPLAD_00635	2.57e-158	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HEGBPLAD_00636	3.99e-177	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HEGBPLAD_00637	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HEGBPLAD_00638	5.27e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HEGBPLAD_00639	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HEGBPLAD_00640	6.3e-95	-	-	-	-	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	-
HEGBPLAD_00641	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HEGBPLAD_00642	9.23e-108	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HEGBPLAD_00643	1.71e-302	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HEGBPLAD_00644	1.39e-200	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HEGBPLAD_00646	1.13e-197	-	-	-	G	-	-	-	Peptidase_C39 like family
HEGBPLAD_00647	5.31e-217	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HEGBPLAD_00648	2.43e-174	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HEGBPLAD_00649	4.41e-218	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HEGBPLAD_00650	9.05e-85	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
HEGBPLAD_00651	0.0	levR	-	-	K	-	-	-	Sigma-54 interaction domain
HEGBPLAD_00652	7.19e-94	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HEGBPLAD_00653	9.09e-113	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HEGBPLAD_00654	1.82e-228	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HEGBPLAD_00655	9.24e-85	accB1	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin-requiring enzyme
HEGBPLAD_00656	3.4e-315	accC1	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
HEGBPLAD_00657	1.01e-181	accD1	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HEGBPLAD_00658	1.23e-177	accA1	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
HEGBPLAD_00659	1.54e-232	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HEGBPLAD_00660	3.06e-214	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HEGBPLAD_00661	1.17e-224	-	-	-	EG	-	-	-	EamA-like transporter family
HEGBPLAD_00662	2.23e-164	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HEGBPLAD_00663	4.3e-85	zmp2	-	-	O	-	-	-	Zinc-dependent metalloprotease
HEGBPLAD_00664	2.79e-42	zmp2	-	-	O	-	-	-	Zinc-dependent metalloprotease
HEGBPLAD_00665	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HEGBPLAD_00666	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HEGBPLAD_00667	6.18e-197	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
HEGBPLAD_00668	6.57e-291	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HEGBPLAD_00669	2.43e-264	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HEGBPLAD_00670	8.63e-292	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HEGBPLAD_00671	1.92e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HEGBPLAD_00672	5.74e-172	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HEGBPLAD_00673	1.92e-316	ymfH	-	-	S	-	-	-	Peptidase M16
HEGBPLAD_00674	2.91e-295	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HEGBPLAD_00675	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HEGBPLAD_00676	2.61e-199	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HEGBPLAD_00677	5.26e-148	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HEGBPLAD_00678	1.89e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HEGBPLAD_00679	1.23e-187	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HEGBPLAD_00680	3.66e-148	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HEGBPLAD_00681	9.47e-115	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HEGBPLAD_00682	3.76e-184	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HEGBPLAD_00683	1.74e-211	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HEGBPLAD_00684	5.96e-70	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HEGBPLAD_00685	5.28e-17	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HEGBPLAD_00686	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HEGBPLAD_00687	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HEGBPLAD_00688	3.56e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HEGBPLAD_00689	1.57e-299	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
HEGBPLAD_00690	1.22e-288	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HEGBPLAD_00691	1.75e-275	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HEGBPLAD_00693	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HEGBPLAD_00694	1.51e-104	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HEGBPLAD_00695	2.15e-137	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HEGBPLAD_00696	4.02e-145	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HEGBPLAD_00697	3.29e-104	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HEGBPLAD_00698	1.57e-142	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HEGBPLAD_00699	4.54e-59	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HEGBPLAD_00700	1.19e-289	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HEGBPLAD_00701	2.63e-16	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HEGBPLAD_00702	2.63e-160	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HEGBPLAD_00703	1.56e-155	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HEGBPLAD_00704	1.08e-245	-	-	-	-	-	-	-	-
HEGBPLAD_00705	3.69e-187	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
HEGBPLAD_00706	1.47e-268	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
HEGBPLAD_00707	3.28e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HEGBPLAD_00708	2.92e-81	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HEGBPLAD_00709	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HEGBPLAD_00710	1.65e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HEGBPLAD_00711	9.72e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HEGBPLAD_00712	1.9e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HEGBPLAD_00713	1.99e-262	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HEGBPLAD_00714	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HEGBPLAD_00715	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HEGBPLAD_00716	3.9e-143	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HEGBPLAD_00717	7.75e-93	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HEGBPLAD_00719	6.17e-165	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
HEGBPLAD_00720	2.08e-92	-	-	-	S	-	-	-	LuxR family transcriptional regulator
HEGBPLAD_00721	7.74e-173	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
HEGBPLAD_00722	1.87e-117	-	-	-	F	-	-	-	NUDIX domain
HEGBPLAD_00723	2.94e-206	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEGBPLAD_00724	2.44e-166	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HEGBPLAD_00725	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HEGBPLAD_00726	1.33e-85	-	-	-	K	-	-	-	Transcriptional regulator
HEGBPLAD_00727	1.11e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
HEGBPLAD_00728	2.89e-100	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
HEGBPLAD_00729	1.96e-168	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HEGBPLAD_00730	1.57e-22	-	-	-	-	-	-	-	-
HEGBPLAD_00731	2.37e-65	-	-	-	-	-	-	-	-
HEGBPLAD_00732	1.98e-190	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HEGBPLAD_00733	1.92e-264	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
HEGBPLAD_00735	1.09e-66	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
HEGBPLAD_00736	6.02e-166	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
HEGBPLAD_00737	8.65e-176	XK27_00890	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
HEGBPLAD_00738	1.23e-311	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HEGBPLAD_00739	2e-174	-	-	-	-	-	-	-	-
HEGBPLAD_00740	3.71e-76	-	-	-	-	-	-	-	-
HEGBPLAD_00741	2.36e-54	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HEGBPLAD_00742	9.11e-176	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HEGBPLAD_00743	2.44e-84	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HEGBPLAD_00744	5.54e-289	-	-	-	-	-	-	-	-
HEGBPLAD_00745	7.15e-165	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HEGBPLAD_00746	2.44e-242	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HEGBPLAD_00747	8.24e-250	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	H	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HEGBPLAD_00748	0.0	tarL	2.7.8.14, 2.7.8.47	-	H	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HEGBPLAD_00749	4.68e-121	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HEGBPLAD_00750	9.27e-93	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEGBPLAD_00751	3.92e-305	gshR1	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HEGBPLAD_00752	3.02e-33	-	-	-	-	-	-	-	-
HEGBPLAD_00753	1.32e-307	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HEGBPLAD_00754	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HEGBPLAD_00755	8.45e-203	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HEGBPLAD_00756	1.07e-43	-	-	-	S	-	-	-	YozE SAM-like fold
HEGBPLAD_00757	9.17e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HEGBPLAD_00758	3.8e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HEGBPLAD_00759	3.91e-216	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HEGBPLAD_00760	3.01e-225	-	-	-	K	-	-	-	Transcriptional regulator
HEGBPLAD_00761	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEGBPLAD_00762	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEGBPLAD_00763	2.4e-137	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HEGBPLAD_00764	7.34e-217	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HEGBPLAD_00765	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HEGBPLAD_00766	6.84e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HEGBPLAD_00767	1.5e-227	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HEGBPLAD_00768	9.43e-317	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HEGBPLAD_00769	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEGBPLAD_00770	1.5e-198	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HEGBPLAD_00771	1.18e-174	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEGBPLAD_00772	2.63e-206	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HEGBPLAD_00773	8.51e-291	XK27_05470	-	-	E	-	-	-	Methionine synthase
HEGBPLAD_00774	2.11e-220	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
HEGBPLAD_00775	1.18e-158	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HEGBPLAD_00776	1.05e-253	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HEGBPLAD_00777	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HEGBPLAD_00778	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HEGBPLAD_00779	9.33e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HEGBPLAD_00780	7.74e-146	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HEGBPLAD_00781	2.28e-203	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HEGBPLAD_00782	6.79e-188	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HEGBPLAD_00783	1.8e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HEGBPLAD_00784	1.35e-240	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HEGBPLAD_00785	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HEGBPLAD_00786	1.07e-107	-	-	-	-	-	-	-	-
HEGBPLAD_00787	2.02e-288	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HEGBPLAD_00788	1.39e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HEGBPLAD_00789	9.93e-167	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HEGBPLAD_00790	5.83e-291	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HEGBPLAD_00791	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HEGBPLAD_00792	2.06e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HEGBPLAD_00793	5.43e-279	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HEGBPLAD_00794	1.22e-149	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HEGBPLAD_00795	1.25e-39	-	-	-	M	-	-	-	Lysin motif
HEGBPLAD_00796	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HEGBPLAD_00797	5.38e-249	-	-	-	S	-	-	-	Helix-turn-helix domain
HEGBPLAD_00798	2.24e-126	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HEGBPLAD_00799	2.69e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HEGBPLAD_00800	1.3e-132	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HEGBPLAD_00801	1.18e-174	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HEGBPLAD_00802	3.99e-92	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEGBPLAD_00803	3.13e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HEGBPLAD_00804	7.94e-218	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HEGBPLAD_00805	7.2e-98	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
HEGBPLAD_00806	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HEGBPLAD_00807	8.69e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HEGBPLAD_00808	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HEGBPLAD_00809	7.03e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HEGBPLAD_00810	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HEGBPLAD_00811	6.39e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HEGBPLAD_00812	6.55e-251	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HEGBPLAD_00813	8.34e-165	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HEGBPLAD_00814	3.47e-286	-	-	-	M	-	-	-	O-Antigen ligase
HEGBPLAD_00815	5.94e-164	drrB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HEGBPLAD_00816	2.71e-153	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HEGBPLAD_00817	1.35e-43	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HEGBPLAD_00818	2.74e-112	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEGBPLAD_00819	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HEGBPLAD_00820	2.01e-50	-	-	-	P	-	-	-	Rhodanese Homology Domain
HEGBPLAD_00821	8.68e-118	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEGBPLAD_00822	9.17e-265	-	-	-	-	-	-	-	-
HEGBPLAD_00823	1.45e-47	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HEGBPLAD_00824	5.04e-231	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HEGBPLAD_00825	6.45e-160	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HEGBPLAD_00826	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HEGBPLAD_00827	7.04e-74	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HEGBPLAD_00828	1.73e-178	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HEGBPLAD_00829	3.61e-304	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
HEGBPLAD_00830	4.38e-102	-	-	-	K	-	-	-	Transcriptional regulator
HEGBPLAD_00831	1.68e-216	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HEGBPLAD_00832	7.96e-37	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HEGBPLAD_00833	0.0	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HEGBPLAD_00834	2.49e-174	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HEGBPLAD_00835	1.25e-140	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HEGBPLAD_00836	1.18e-180	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
HEGBPLAD_00837	1.25e-66	-	-	-	-	-	-	-	-
HEGBPLAD_00838	2.19e-56	-	-	-	-	-	-	-	-
HEGBPLAD_00839	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEGBPLAD_00840	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HEGBPLAD_00841	2.11e-108	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HEGBPLAD_00842	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HEGBPLAD_00843	6.85e-157	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HEGBPLAD_00844	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HEGBPLAD_00845	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HEGBPLAD_00846	4.77e-247	galM2	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HEGBPLAD_00847	2.88e-249	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HEGBPLAD_00848	1.4e-259	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HEGBPLAD_00849	1.28e-229	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HEGBPLAD_00850	4.23e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HEGBPLAD_00851	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HEGBPLAD_00852	8.48e-106	ypmB	-	-	S	-	-	-	protein conserved in bacteria
HEGBPLAD_00853	1.41e-285	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HEGBPLAD_00854	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HEGBPLAD_00855	3.25e-165	dnaD	-	-	L	ko:K02086	-	ko00000	Replication initiation and membrane attachment
HEGBPLAD_00857	9.85e-240	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HEGBPLAD_00858	1.41e-141	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HEGBPLAD_00859	4.53e-203	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HEGBPLAD_00860	7.56e-109	-	-	-	T	-	-	-	Universal stress protein family
HEGBPLAD_00861	0.0	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HEGBPLAD_00862	3.48e-218	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HEGBPLAD_00863	5.65e-229	phnT	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HEGBPLAD_00864	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HEGBPLAD_00865	3.6e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HEGBPLAD_00866	2.12e-142	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HEGBPLAD_00867	9.98e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HEGBPLAD_00869	1.18e-281	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HEGBPLAD_00870	4.17e-186	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HEGBPLAD_00871	3.2e-95	-	-	-	S	-	-	-	SnoaL-like domain
HEGBPLAD_00872	8.87e-119	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HEGBPLAD_00873	2.66e-97	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
HEGBPLAD_00874	2.46e-126	-	-	-	-	-	-	-	-
HEGBPLAD_00875	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HEGBPLAD_00876	3.31e-142	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HEGBPLAD_00877	1.55e-225	-	-	-	K	-	-	-	LysR substrate binding domain
HEGBPLAD_00878	2.12e-227	-	-	-	M	-	-	-	Peptidase family S41
HEGBPLAD_00879	4.99e-271	-	-	-	-	-	-	-	-
HEGBPLAD_00880	2.95e-240	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HEGBPLAD_00881	0.0	yhaN	-	-	L	-	-	-	AAA domain
HEGBPLAD_00882	4.28e-294	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HEGBPLAD_00883	2.85e-70	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HEGBPLAD_00884	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HEGBPLAD_00885	2.01e-17	-	-	-	-	-	-	-	-
HEGBPLAD_00886	2.07e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HEGBPLAD_00887	1.08e-268	arcT	-	-	E	-	-	-	Aminotransferase
HEGBPLAD_00888	2.28e-132	argO	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
HEGBPLAD_00889	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	Alanine-glyoxylate amino-transferase
HEGBPLAD_00890	1.65e-46	dltC2	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEGBPLAD_00891	2.85e-147	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HEGBPLAD_00892	3.13e-274	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
HEGBPLAD_00893	1.43e-104	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HEGBPLAD_00894	1.45e-198	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HEGBPLAD_00895	1.02e-285	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEGBPLAD_00896	4.9e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HEGBPLAD_00897	9.64e-68	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HEGBPLAD_00898	1.34e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HEGBPLAD_00899	0.0	celR	-	-	K	-	-	-	PRD domain
HEGBPLAD_00900	3.61e-137	-	-	-	-	-	-	-	-
HEGBPLAD_00901	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HEGBPLAD_00902	2.67e-95	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HEGBPLAD_00903	1.81e-103	-	-	-	-	-	-	-	-
HEGBPLAD_00904	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HEGBPLAD_00905	1.42e-102	yybD	-	-	S	ko:K02348	-	ko00000	Acetyltransferase (GNAT) domain
HEGBPLAD_00908	1.79e-42	-	-	-	-	-	-	-	-
HEGBPLAD_00909	1.8e-315	dinF	-	-	V	-	-	-	MatE
HEGBPLAD_00910	0.0	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HEGBPLAD_00911	9.32e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HEGBPLAD_00912	2.04e-274	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HEGBPLAD_00913	4.28e-84	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HEGBPLAD_00914	2.58e-65	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HEGBPLAD_00915	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HEGBPLAD_00916	5.58e-248	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	ABC transporter, substratebinding protein
HEGBPLAD_00917	1.23e-201	-	-	-	U	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HEGBPLAD_00918	2.02e-171	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HEGBPLAD_00919	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HEGBPLAD_00920	2.14e-259	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HEGBPLAD_00922	2.05e-208	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HEGBPLAD_00923	5.62e-293	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HEGBPLAD_00924	2.36e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HEGBPLAD_00925	1.23e-273	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
HEGBPLAD_00926	2.16e-240	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HEGBPLAD_00927	1.3e-110	queT	-	-	S	-	-	-	QueT transporter
HEGBPLAD_00928	4.87e-148	-	-	-	S	-	-	-	(CBS) domain
HEGBPLAD_00929	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HEGBPLAD_00930	2.79e-226	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HEGBPLAD_00931	1.43e-129	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HEGBPLAD_00932	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HEGBPLAD_00933	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HEGBPLAD_00934	7.72e-57	yabO	-	-	J	-	-	-	S4 domain protein
HEGBPLAD_00936	2.36e-82	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HEGBPLAD_00937	1.07e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HEGBPLAD_00938	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HEGBPLAD_00939	4.3e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HEGBPLAD_00940	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HEGBPLAD_00941	1.58e-208	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HEGBPLAD_00942	1.24e-236	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEGBPLAD_00943	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HEGBPLAD_00945	9.78e-102	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HEGBPLAD_00946	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HEGBPLAD_00947	1.16e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HEGBPLAD_00948	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEGBPLAD_00949	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEGBPLAD_00950	2.36e-146	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HEGBPLAD_00951	4.19e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HEGBPLAD_00952	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HEGBPLAD_00953	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HEGBPLAD_00954	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HEGBPLAD_00955	4.34e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HEGBPLAD_00956	9.83e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HEGBPLAD_00957	9.27e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HEGBPLAD_00958	6.61e-193	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HEGBPLAD_00959	1.85e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HEGBPLAD_00960	1.46e-68	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HEGBPLAD_00961	5.46e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HEGBPLAD_00962	8.29e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HEGBPLAD_00963	1.11e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HEGBPLAD_00964	1.96e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HEGBPLAD_00965	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HEGBPLAD_00966	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HEGBPLAD_00967	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HEGBPLAD_00968	4.99e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HEGBPLAD_00969	3.54e-122	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HEGBPLAD_00970	1.75e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HEGBPLAD_00971	5.32e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HEGBPLAD_00972	8.44e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HEGBPLAD_00973	1.32e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HEGBPLAD_00974	5.95e-300	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HEGBPLAD_00975	4.34e-159	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HEGBPLAD_00976	9.87e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HEGBPLAD_00977	9.65e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HEGBPLAD_00978	7.71e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HEGBPLAD_00979	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEGBPLAD_00980	7.76e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HEGBPLAD_00981	1.1e-230	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HEGBPLAD_00982	6.71e-121	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
HEGBPLAD_00983	1.27e-110	-	-	-	S	-	-	-	NusG domain II
HEGBPLAD_00984	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HEGBPLAD_00985	3.56e-97	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HEGBPLAD_00986	7.83e-140	-	-	-	-	-	-	-	-
HEGBPLAD_00987	3.82e-189	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HEGBPLAD_00988	3.13e-203	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HEGBPLAD_00990	1.32e-22	-	-	-	GM	-	-	-	NAD(P)H-binding
HEGBPLAD_00991	5.2e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HEGBPLAD_00992	2.33e-196	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HEGBPLAD_00994	6.05e-225	-	-	-	K	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
HEGBPLAD_00995	7.5e-202	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HEGBPLAD_00996	4.54e-158	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HEGBPLAD_00998	1.69e-316	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
HEGBPLAD_00999	3.55e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HEGBPLAD_01000	2.07e-155	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HEGBPLAD_01001	3.53e-158	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HEGBPLAD_01002	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HEGBPLAD_01003	3.56e-192	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HEGBPLAD_01004	3.93e-222	ugpA	-	-	U	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HEGBPLAD_01005	2.68e-254	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
HEGBPLAD_01006	1.73e-72	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HEGBPLAD_01007	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HEGBPLAD_01008	7.14e-192	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HEGBPLAD_01009	2.05e-175	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HEGBPLAD_01010	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HEGBPLAD_01011	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HEGBPLAD_01012	2.95e-160	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HEGBPLAD_01013	1.02e-120	mraW1	-	-	J	-	-	-	Putative rRNA methylase
HEGBPLAD_01014	9.32e-40	-	-	-	-	-	-	-	-
HEGBPLAD_01015	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HEGBPLAD_01016	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HEGBPLAD_01017	0.0	-	-	-	S	-	-	-	Pfam Methyltransferase
HEGBPLAD_01018	6.56e-22	-	-	-	N	-	-	-	Cell shape-determining protein MreB
HEGBPLAD_01020	2.41e-37	-	-	-	-	-	-	-	-
HEGBPLAD_01021	2.69e-169	-	-	-	S	-	-	-	YheO-like PAS domain
HEGBPLAD_01022	2.81e-202	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HEGBPLAD_01023	1.52e-158	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HEGBPLAD_01024	2.28e-290	sdaC	-	-	E	ko:K03837	-	ko00000,ko02000	amino acid
HEGBPLAD_01025	4.79e-311	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HEGBPLAD_01026	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HEGBPLAD_01027	2.96e-89	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HEGBPLAD_01028	2.87e-101	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HEGBPLAD_01029	7.37e-199	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
HEGBPLAD_01030	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HEGBPLAD_01031	1.45e-191	yxeH	-	-	S	-	-	-	hydrolase
HEGBPLAD_01032	9.84e-49	-	-	-	-	-	-	-	-
HEGBPLAD_01033	9.66e-114	-	-	-	-	-	-	-	-
HEGBPLAD_01034	2.82e-236	-	-	-	S	-	-	-	DUF218 domain
HEGBPLAD_01035	3.26e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HEGBPLAD_01036	5.02e-190	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HEGBPLAD_01037	3.28e-298	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HEGBPLAD_01038	1.96e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HEGBPLAD_01039	9.15e-50	-	-	-	-	-	-	-	-
HEGBPLAD_01040	5.93e-57	-	-	-	S	-	-	-	ankyrin repeats
HEGBPLAD_01041	5.67e-27	-	-	-	M	ko:K21493	-	ko00000,ko01000,ko02048	self proteolysis
HEGBPLAD_01042	1.83e-168	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HEGBPLAD_01043	2.31e-165	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HEGBPLAD_01044	1.34e-37	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
HEGBPLAD_01045	5.65e-135	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
HEGBPLAD_01046	6.21e-207	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HEGBPLAD_01047	6.87e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HEGBPLAD_01048	2.92e-202	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HEGBPLAD_01049	1.6e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HEGBPLAD_01050	6.64e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HEGBPLAD_01052	3.05e-135	mutR	-	-	K	ko:K20373,ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
HEGBPLAD_01053	1.42e-270	-	-	-	EGP	ko:K02030	-	ko00000,ko00002,ko02000	Drug resistance transporter Bcr CflA subfamily
HEGBPLAD_01054	7.41e-48	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HEGBPLAD_01055	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HEGBPLAD_01056	1.23e-294	-	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
HEGBPLAD_01057	0.0	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HEGBPLAD_01058	3.41e-296	-	-	-	P	ko:K06610	-	ko00000,ko02000	Major Facilitator Superfamily
HEGBPLAD_01059	1.51e-234	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HEGBPLAD_01060	1.37e-120	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HEGBPLAD_01061	9.67e-84	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HEGBPLAD_01062	1.33e-231	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HEGBPLAD_01063	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HEGBPLAD_01064	1.26e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HEGBPLAD_01065	9.52e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HEGBPLAD_01066	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HEGBPLAD_01067	6.41e-236	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HEGBPLAD_01068	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HEGBPLAD_01069	9.37e-69	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HEGBPLAD_01070	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HEGBPLAD_01071	4.78e-250	galM3	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HEGBPLAD_01072	4.3e-231	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HEGBPLAD_01073	1.32e-129	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HEGBPLAD_01074	1.98e-93	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HEGBPLAD_01075	1.12e-82	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
HEGBPLAD_01076	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HEGBPLAD_01077	9.71e-226	apbE3	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HEGBPLAD_01078	2.2e-173	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HEGBPLAD_01079	2.17e-210	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HEGBPLAD_01080	1.88e-223	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HEGBPLAD_01081	9.06e-279	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HEGBPLAD_01082	3.36e-60	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HEGBPLAD_01084	1.33e-225	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family 2
HEGBPLAD_01085	9.77e-84	-	-	-	-	-	-	-	-
HEGBPLAD_01086	2.03e-100	-	-	-	-	-	-	-	-
HEGBPLAD_01087	8.64e-274	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HEGBPLAD_01088	6.4e-122	-	-	-	-	-	-	-	-
HEGBPLAD_01089	3.09e-121	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
HEGBPLAD_01090	2.07e-148	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HEGBPLAD_01091	7.68e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
HEGBPLAD_01092	3.96e-44	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HEGBPLAD_01093	1.71e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HEGBPLAD_01094	2.57e-172	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HEGBPLAD_01095	3.99e-64	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HEGBPLAD_01096	1.92e-239	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEGBPLAD_01097	1.97e-170	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
HEGBPLAD_01098	6.33e-185	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HEGBPLAD_01099	1.88e-194	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HEGBPLAD_01100	3.01e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HEGBPLAD_01101	6.92e-113	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HEGBPLAD_01102	1.51e-188	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HEGBPLAD_01103	3.23e-175	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HEGBPLAD_01104	1.81e-291	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HEGBPLAD_01105	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HEGBPLAD_01106	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEGBPLAD_01107	9.74e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HEGBPLAD_01108	6.61e-277	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HEGBPLAD_01109	8.46e-65	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HEGBPLAD_01110	3.28e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
HEGBPLAD_01111	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HEGBPLAD_01112	3.04e-71	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HEGBPLAD_01114	1.3e-209	-	-	-	K	-	-	-	Transcriptional regulator
HEGBPLAD_01115	1.71e-206	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HEGBPLAD_01116	1.42e-212	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
HEGBPLAD_01117	2.45e-101	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HEGBPLAD_01118	0.0	ycaM	-	-	E	-	-	-	amino acid
HEGBPLAD_01119	4.4e-160	aroC1	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
HEGBPLAD_01120	4.3e-44	-	-	-	-	-	-	-	-
HEGBPLAD_01121	0.0	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HEGBPLAD_01122	4.18e-225	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HEGBPLAD_01123	2.29e-70	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HEGBPLAD_01124	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HEGBPLAD_01125	2.75e-100	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HEGBPLAD_01126	0.0	-	-	-	-	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	-
HEGBPLAD_01127	1.21e-128	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HEGBPLAD_01128	1.54e-221	serA1	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HEGBPLAD_01129	3.98e-204	-	-	-	EG	-	-	-	EamA-like transporter family
HEGBPLAD_01130	7.17e-234	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEGBPLAD_01131	5.06e-196	-	-	-	S	-	-	-	hydrolase
HEGBPLAD_01132	7.63e-107	-	-	-	-	-	-	-	-
HEGBPLAD_01133	1.75e-156	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
HEGBPLAD_01134	3.3e-180	epsV	-	-	S	-	-	-	glycosyl transferase family 2
HEGBPLAD_01135	1.5e-167	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HEGBPLAD_01136	1.86e-64	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HEGBPLAD_01137	6.7e-74	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
HEGBPLAD_01138	0.0	pbg5	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HEGBPLAD_01139	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HEGBPLAD_01140	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HEGBPLAD_01141	3.36e-306	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
HEGBPLAD_01142	2.15e-123	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HEGBPLAD_01143	4.37e-142	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HEGBPLAD_01144	4.75e-147	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HEGBPLAD_01145	2.47e-45	-	-	-	S	ko:K07334	-	ko00000,ko02048	RelE-like toxin of type II toxin-antitoxin system HigB
HEGBPLAD_01146	3.49e-63	axe	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
HEGBPLAD_01147	0.0	-	-	-	L	-	-	-	DNA helicase
HEGBPLAD_01148	3.54e-182	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HEGBPLAD_01149	4.74e-243	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HEGBPLAD_01150	1.1e-165	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HEGBPLAD_01151	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEGBPLAD_01152	9.68e-34	-	-	-	-	-	-	-	-
HEGBPLAD_01153	4.15e-98	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HEGBPLAD_01154	0.0	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEGBPLAD_01155	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HEGBPLAD_01156	8.13e-208	-	-	-	GK	-	-	-	ROK family
HEGBPLAD_01157	9.75e-175	yecA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HEGBPLAD_01158	1.63e-241	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEGBPLAD_01159	3.21e-213	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HEGBPLAD_01160	2.65e-288	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HEGBPLAD_01161	2.69e-228	-	-	-	-	-	-	-	-
HEGBPLAD_01162	2.06e-169	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HEGBPLAD_01163	5.23e-179	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HEGBPLAD_01164	4.64e-92	-	-	-	F	-	-	-	DNA mismatch repair protein MutT
HEGBPLAD_01165	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HEGBPLAD_01166	2.19e-07	-	-	-	K	-	-	-	transcriptional regulator
HEGBPLAD_01167	4.96e-113	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
HEGBPLAD_01168	4.62e-193	-	-	-	O	-	-	-	Band 7 protein
HEGBPLAD_01169	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HEGBPLAD_01170	6.05e-121	-	-	-	K	-	-	-	transcriptional regulator
HEGBPLAD_01171	1.7e-186	rsgA_2	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HEGBPLAD_01172	1.42e-113	ykhA	-	-	I	-	-	-	Thioesterase superfamily
HEGBPLAD_01173	1.25e-205	-	-	-	K	-	-	-	LysR substrate binding domain
HEGBPLAD_01174	3.01e-162	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HEGBPLAD_01175	1.75e-129	-	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
HEGBPLAD_01176	1.55e-173	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HEGBPLAD_01177	5.63e-178	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HEGBPLAD_01178	2.62e-202	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HEGBPLAD_01179	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HEGBPLAD_01180	8.45e-92	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HEGBPLAD_01181	4.31e-95	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HEGBPLAD_01182	1.54e-289	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HEGBPLAD_01183	1.04e-161	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HEGBPLAD_01184	2.97e-216	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HEGBPLAD_01185	1.06e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEGBPLAD_01186	2.68e-228	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HEGBPLAD_01187	8.55e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HEGBPLAD_01188	3.94e-160	yneE	-	-	K	-	-	-	Transcriptional regulator
HEGBPLAD_01189	4.76e-15	yneE	-	-	K	-	-	-	Transcriptional regulator
HEGBPLAD_01190	1.3e-19	yneE	-	-	K	-	-	-	Transcriptional regulator
HEGBPLAD_01191	9.32e-184	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HEGBPLAD_01192	5.19e-78	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HEGBPLAD_01193	2.3e-253	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HEGBPLAD_01194	4.61e-272	hipO1	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	Peptidase family M20/M25/M40
HEGBPLAD_01195	7.06e-187	-	-	-	E	-	-	-	glutamate:sodium symporter activity
HEGBPLAD_01196	4.04e-74	-	-	-	E	-	-	-	glutamate:sodium symporter activity
HEGBPLAD_01197	1.95e-88	ybbJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HEGBPLAD_01198	5.01e-227	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
HEGBPLAD_01199	3.98e-124	entB	-	-	Q	-	-	-	Isochorismatase family
HEGBPLAD_01200	7.99e-182	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HEGBPLAD_01201	1.79e-287	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HEGBPLAD_01202	9.09e-142	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HEGBPLAD_01203	2.41e-165	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HEGBPLAD_01204	2.01e-224	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HEGBPLAD_01205	2.22e-132	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
HEGBPLAD_01206	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
HEGBPLAD_01208	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HEGBPLAD_01209	1.88e-175	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HEGBPLAD_01210	1.1e-112	-	-	-	-	-	-	-	-
HEGBPLAD_01211	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HEGBPLAD_01212	8.49e-66	-	-	-	-	-	-	-	-
HEGBPLAD_01213	3.15e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HEGBPLAD_01214	1.57e-179	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HEGBPLAD_01215	2.24e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HEGBPLAD_01216	9.99e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HEGBPLAD_01217	1.6e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HEGBPLAD_01218	7.69e-300	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HEGBPLAD_01219	1.46e-77	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HEGBPLAD_01220	4.13e-275	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HEGBPLAD_01221	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HEGBPLAD_01222	4.49e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HEGBPLAD_01223	3.33e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEGBPLAD_01224	2.82e-239	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HEGBPLAD_01225	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HEGBPLAD_01226	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HEGBPLAD_01227	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HEGBPLAD_01228	1.61e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HEGBPLAD_01229	7.2e-158	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HEGBPLAD_01230	2.22e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HEGBPLAD_01231	6.97e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HEGBPLAD_01232	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HEGBPLAD_01233	3.81e-172	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HEGBPLAD_01234	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HEGBPLAD_01235	5.81e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HEGBPLAD_01236	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEGBPLAD_01237	1.06e-275	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HEGBPLAD_01238	3.93e-41	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HEGBPLAD_01239	6.96e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HEGBPLAD_01240	8.28e-73	-	-	-	-	-	-	-	-
HEGBPLAD_01241	1.36e-136	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HEGBPLAD_01242	2.57e-222	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HEGBPLAD_01243	1.18e-133	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HEGBPLAD_01244	1.84e-283	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HEGBPLAD_01245	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HEGBPLAD_01246	5.28e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HEGBPLAD_01247	5.24e-191	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HEGBPLAD_01248	8.53e-203	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HEGBPLAD_01249	7.55e-44	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEGBPLAD_01250	3.14e-310	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEGBPLAD_01251	2.79e-193	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HEGBPLAD_01252	9.43e-90	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HEGBPLAD_01253	1.7e-96	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HEGBPLAD_01254	1.43e-129	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HEGBPLAD_01255	6.04e-249	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HEGBPLAD_01256	2.33e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HEGBPLAD_01257	1.09e-68	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HEGBPLAD_01258	1.55e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HEGBPLAD_01259	8.15e-125	-	-	-	K	-	-	-	Transcriptional regulator
HEGBPLAD_01260	9.81e-27	-	-	-	-	-	-	-	-
HEGBPLAD_01263	3.48e-40	-	-	-	-	-	-	-	-
HEGBPLAD_01264	3.11e-73	-	-	-	-	-	-	-	-
HEGBPLAD_01265	2.92e-126	-	-	-	S	-	-	-	Protein conserved in bacteria
HEGBPLAD_01266	2.7e-232	-	-	-	-	-	-	-	-
HEGBPLAD_01267	4.11e-206	-	-	-	-	-	-	-	-
HEGBPLAD_01268	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HEGBPLAD_01269	7.79e-85	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
HEGBPLAD_01270	6.58e-225	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HEGBPLAD_01271	1.83e-177	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HEGBPLAD_01272	1.44e-31	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HEGBPLAD_01273	1.15e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HEGBPLAD_01274	5.43e-140	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HEGBPLAD_01275	2.6e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HEGBPLAD_01276	6.33e-46	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HEGBPLAD_01277	6.8e-151	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HEGBPLAD_01278	9.29e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HEGBPLAD_01279	5.33e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HEGBPLAD_01280	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HEGBPLAD_01281	0.0	-	-	-	S	-	-	-	membrane
HEGBPLAD_01282	6.12e-72	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HEGBPLAD_01283	1.92e-97	-	-	-	K	-	-	-	LytTr DNA-binding domain
HEGBPLAD_01284	7.98e-145	-	-	-	S	-	-	-	membrane
HEGBPLAD_01285	1.09e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HEGBPLAD_01286	7.5e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HEGBPLAD_01287	6.11e-249	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HEGBPLAD_01288	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEGBPLAD_01289	6.88e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HEGBPLAD_01290	3.13e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HEGBPLAD_01291	1.72e-120	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HEGBPLAD_01292	1.82e-178	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEGBPLAD_01293	2.36e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HEGBPLAD_01294	1.4e-208	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEGBPLAD_01295	1.46e-121	-	-	-	S	-	-	-	SdpI/YhfL protein family
HEGBPLAD_01296	9.59e-289	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HEGBPLAD_01297	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HEGBPLAD_01298	3.17e-171	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HEGBPLAD_01300	7.76e-314	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HEGBPLAD_01301	1.86e-243	mocA	-	-	S	-	-	-	Oxidoreductase
HEGBPLAD_01302	6.22e-43	cspP	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HEGBPLAD_01303	8.58e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HEGBPLAD_01304	4.68e-187	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HEGBPLAD_01305	1.88e-194	gntR	-	-	K	-	-	-	rpiR family
HEGBPLAD_01306	1.64e-109	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HEGBPLAD_01307	3.3e-79	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HEGBPLAD_01308	8.35e-30	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEGBPLAD_01309	1.29e-261	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEGBPLAD_01310	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HEGBPLAD_01311	5.56e-130	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HEGBPLAD_01312	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEGBPLAD_01313	1.59e-242	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HEGBPLAD_01314	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEGBPLAD_01315	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HEGBPLAD_01316	5.11e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEGBPLAD_01317	9.48e-263	camS	-	-	S	-	-	-	sex pheromone
HEGBPLAD_01318	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HEGBPLAD_01319	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HEGBPLAD_01320	1.39e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HEGBPLAD_01321	1.13e-120	yebE	-	-	S	-	-	-	UPF0316 protein
HEGBPLAD_01322	1.65e-133	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HEGBPLAD_01323	3.41e-146	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HEGBPLAD_01324	2.23e-234	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HEGBPLAD_01325	1.75e-47	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HEGBPLAD_01326	2.36e-154	azlC	-	-	E	-	-	-	branched-chain amino acid
HEGBPLAD_01327	3.43e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HEGBPLAD_01328	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HEGBPLAD_01329	9.43e-279	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HEGBPLAD_01330	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HEGBPLAD_01331	0.0	xylP2	-	-	G	-	-	-	symporter
HEGBPLAD_01332	9.56e-243	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HEGBPLAD_01333	3.33e-64	-	-	-	-	-	-	-	-
HEGBPLAD_01334	2.14e-156	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
HEGBPLAD_01335	3.23e-130	-	-	-	K	-	-	-	FR47-like protein
HEGBPLAD_01336	8.44e-163	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HEGBPLAD_01337	2.41e-280	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HEGBPLAD_01338	2.26e-243	-	-	-	-	-	-	-	-
HEGBPLAD_01339	8.34e-179	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HEGBPLAD_01340	5.06e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HEGBPLAD_01341	9.95e-211	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HEGBPLAD_01342	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HEGBPLAD_01343	4.95e-44	-	-	-	L	-	-	-	leucine-zipper of insertion element IS481
HEGBPLAD_01344	9.05e-55	-	-	-	-	-	-	-	-
HEGBPLAD_01345	7.32e-288	-	-	-	L	-	-	-	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HEGBPLAD_01346	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HEGBPLAD_01347	2.78e-254	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HEGBPLAD_01348	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HEGBPLAD_01349	2.37e-50	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HEGBPLAD_01350	1.32e-74	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HEGBPLAD_01351	4.13e-104	-	-	-	K	-	-	-	Transcriptional regulator
HEGBPLAD_01352	1.5e-127	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HEGBPLAD_01353	1.68e-269	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HEGBPLAD_01354	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HEGBPLAD_01355	1.45e-148	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HEGBPLAD_01356	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HEGBPLAD_01357	1.89e-170	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HEGBPLAD_01358	1.33e-135	-	-	-	-	-	-	-	-
HEGBPLAD_01359	8.06e-199	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HEGBPLAD_01360	8.11e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HEGBPLAD_01361	1.23e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HEGBPLAD_01362	7.5e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HEGBPLAD_01363	1.03e-113	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HEGBPLAD_01364	7.18e-131	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HEGBPLAD_01365	2.53e-198	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HEGBPLAD_01366	1.41e-209	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
HEGBPLAD_01367	7.28e-213	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HEGBPLAD_01368	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HEGBPLAD_01369	3.07e-119	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEGBPLAD_01370	5.68e-156	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
HEGBPLAD_01371	8.33e-192	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HEGBPLAD_01372	8.77e-180	ybbR	-	-	S	-	-	-	YbbR-like protein
HEGBPLAD_01373	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HEGBPLAD_01374	4.59e-116	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HEGBPLAD_01376	3.65e-90	-	-	-	-	-	-	-	-
HEGBPLAD_01377	1.19e-186	-	-	-	S	ko:K06889	-	ko00000	Dienelactone hydrolase family
HEGBPLAD_01378	9.89e-74	ytpP	-	-	CO	-	-	-	Thioredoxin
HEGBPLAD_01379	9.11e-261	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HEGBPLAD_01380	1.58e-61	-	-	-	-	-	-	-	-
HEGBPLAD_01381	9.34e-71	-	-	-	-	-	-	-	-
HEGBPLAD_01382	5.7e-105	-	-	-	S	-	-	-	Protein of unknown function (DUF2798)
HEGBPLAD_01383	2.74e-96	-	-	-	-	-	-	-	-
HEGBPLAD_01384	5.7e-77	-	-	-	-	-	-	-	-
HEGBPLAD_01385	4.26e-250	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HEGBPLAD_01386	0.0	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
HEGBPLAD_01387	1.45e-102	uspA3	-	-	T	-	-	-	universal stress protein
HEGBPLAD_01388	1.69e-201	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HEGBPLAD_01389	8.17e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HEGBPLAD_01390	7.97e-246	-	-	-	M	-	-	-	Glycosyl transferases group 1
HEGBPLAD_01391	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HEGBPLAD_01392	4.23e-211	-	-	-	S	-	-	-	Putative esterase
HEGBPLAD_01393	3.53e-169	-	-	-	K	-	-	-	Transcriptional regulator
HEGBPLAD_01394	2.75e-116	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HEGBPLAD_01395	6.08e-179	-	-	-	-	-	-	-	-
HEGBPLAD_01396	1.97e-150	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HEGBPLAD_01397	8.05e-179	rrp8	-	-	K	-	-	-	LytTr DNA-binding domain
HEGBPLAD_01398	1.7e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HEGBPLAD_01399	1.55e-79	-	-	-	-	-	-	-	-
HEGBPLAD_01400	7.48e-96	hsp2	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HEGBPLAD_01401	2.97e-76	-	-	-	-	-	-	-	-
HEGBPLAD_01402	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HEGBPLAD_01403	2.8e-63	-	-	-	-	-	-	-	-
HEGBPLAD_01404	4.31e-76	-	-	-	-	-	-	-	-
HEGBPLAD_01405	8.85e-209	-	-	-	-	-	-	-	-
HEGBPLAD_01406	1.4e-95	-	-	-	K	-	-	-	Transcriptional regulator
HEGBPLAD_01407	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
HEGBPLAD_01408	5.39e-222	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HEGBPLAD_01409	4.17e-60	-	-	-	S	-	-	-	Enterocin A Immunity
HEGBPLAD_01410	3.4e-85	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
HEGBPLAD_01411	5e-162	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HEGBPLAD_01412	1.54e-171	-	-	-	-	-	-	-	-
HEGBPLAD_01413	7.71e-138	pncA	-	-	Q	-	-	-	Isochorismatase family
HEGBPLAD_01414	2e-105	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HEGBPLAD_01415	2.93e-304	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HEGBPLAD_01416	0.0	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HEGBPLAD_01417	1.09e-253	yhhX	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HEGBPLAD_01418	6.09e-228	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HEGBPLAD_01419	1.19e-149	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HEGBPLAD_01420	1.48e-201	ccpB	-	-	K	-	-	-	lacI family
HEGBPLAD_01421	1.27e-156	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HEGBPLAD_01422	2.84e-208	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEGBPLAD_01423	7.13e-228	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HEGBPLAD_01424	1.49e-127	-	-	-	C	-	-	-	Nitroreductase family
HEGBPLAD_01425	6.04e-217	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HEGBPLAD_01426	7.79e-243	-	-	-	S	-	-	-	domain, Protein
HEGBPLAD_01427	7.06e-173	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HEGBPLAD_01428	2.32e-235	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HEGBPLAD_01429	5.5e-93	-	-	-	-	-	-	-	-
HEGBPLAD_01430	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HEGBPLAD_01431	1.64e-113	-	-	-	-	-	-	-	-
HEGBPLAD_01432	1.64e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HEGBPLAD_01433	1.52e-238	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HEGBPLAD_01434	5.87e-256	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HEGBPLAD_01435	9.91e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HEGBPLAD_01436	1.32e-63	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HEGBPLAD_01437	2.48e-276	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEGBPLAD_01438	8.32e-227	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HEGBPLAD_01439	2.05e-315	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HEGBPLAD_01440	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HEGBPLAD_01441	5e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HEGBPLAD_01442	5.39e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HEGBPLAD_01443	1.31e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HEGBPLAD_01444	1.06e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HEGBPLAD_01445	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HEGBPLAD_01446	3e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HEGBPLAD_01447	2.57e-118	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HEGBPLAD_01448	8.74e-195	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HEGBPLAD_01449	1.21e-143	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HEGBPLAD_01450	7.83e-123	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HEGBPLAD_01451	7.94e-114	ykuL	-	-	S	-	-	-	(CBS) domain
HEGBPLAD_01452	2.29e-112	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HEGBPLAD_01453	1.3e-286	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HEGBPLAD_01454	3.41e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEGBPLAD_01455	1.86e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HEGBPLAD_01456	4.88e-240	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HEGBPLAD_01457	7.14e-157	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEGBPLAD_01458	2.76e-117	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
HEGBPLAD_01459	5.72e-238	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HEGBPLAD_01460	3.55e-127	ywjB	-	-	H	-	-	-	RibD C-terminal domain
HEGBPLAD_01461	9.77e-259	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HEGBPLAD_01462	4.28e-153	-	-	-	S	-	-	-	Membrane
HEGBPLAD_01463	2.46e-198	mleP3	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HEGBPLAD_01464	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
HEGBPLAD_01465	3.04e-261	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HEGBPLAD_01466	7.22e-163	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HEGBPLAD_01467	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HEGBPLAD_01468	6.15e-101	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HEGBPLAD_01469	2.21e-133	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HEGBPLAD_01470	1.78e-221	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HEGBPLAD_01471	5.9e-194	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HEGBPLAD_01472	0.0	tagE5	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
HEGBPLAD_01473	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HEGBPLAD_01475	9.57e-87	-	-	-	M	-	-	-	LysM domain
HEGBPLAD_01476	1.6e-119	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
HEGBPLAD_01477	5.48e-171	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HEGBPLAD_01478	8.23e-226	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HEGBPLAD_01479	0.0	-	-	-	-	-	-	-	-
HEGBPLAD_01480	2.41e-212	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HEGBPLAD_01481	1.58e-66	-	-	-	-	-	-	-	-
HEGBPLAD_01482	6.47e-124	-	-	-	K	ko:K22041	-	ko00000,ko03000	transcriptional regulator
HEGBPLAD_01483	2.83e-116	ymdB	-	-	S	-	-	-	Macro domain protein
HEGBPLAD_01484	1.56e-189	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HEGBPLAD_01485	1.05e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HEGBPLAD_01486	2.07e-102	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HEGBPLAD_01487	2.57e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
HEGBPLAD_01488	9.19e-208	yvgN	-	-	C	-	-	-	Aldo keto reductase
HEGBPLAD_01489	2.3e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HEGBPLAD_01490	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HEGBPLAD_01491	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HEGBPLAD_01492	7.73e-109	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HEGBPLAD_01493	7.13e-100	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HEGBPLAD_01494	5.74e-229	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HEGBPLAD_01495	4.81e-108	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HEGBPLAD_01496	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HEGBPLAD_01497	8.4e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1398)
HEGBPLAD_01498	2.55e-65	-	-	-	-	-	-	-	-
HEGBPLAD_01499	2.94e-34	-	-	-	-	-	-	-	-
HEGBPLAD_01500	8.58e-45	-	-	-	-	-	-	-	-
HEGBPLAD_01501	2.67e-30	-	-	-	-	-	-	-	-
HEGBPLAD_01503	4.03e-207	yhxD	-	-	IQ	-	-	-	KR domain
HEGBPLAD_01504	3.23e-290	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
HEGBPLAD_01505	4.91e-20	-	-	-	-	-	-	-	-
HEGBPLAD_01506	1.02e-61	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HEGBPLAD_01507	7.24e-317	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HEGBPLAD_01508	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HEGBPLAD_01509	3.82e-276	-	-	-	-	-	-	-	-
HEGBPLAD_01510	3.41e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
HEGBPLAD_01511	3.02e-175	gdh	1.1.1.47, 1.1.1.53	-	IQ	ko:K00034,ko:K00038	ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200	ko00000,ko00001,ko01000	reductase
HEGBPLAD_01512	3.55e-79	-	-	-	I	-	-	-	sulfurtransferase activity
HEGBPLAD_01513	6.7e-102	yphH	-	-	S	-	-	-	Cupin domain
HEGBPLAD_01514	1.37e-46	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HEGBPLAD_01515	2.15e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
HEGBPLAD_01516	2.06e-219	-	-	-	C	-	-	-	C4-dicarboxylate transmembrane transporter activity
HEGBPLAD_01517	5.36e-219	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HEGBPLAD_01518	1.17e-214	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HEGBPLAD_01519	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HEGBPLAD_01520	7.43e-97	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HEGBPLAD_01521	1.65e-265	-	-	-	T	-	-	-	diguanylate cyclase
HEGBPLAD_01522	1.3e-153	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
HEGBPLAD_01523	6.85e-104	-	-	-	-	-	-	-	-
HEGBPLAD_01524	2.35e-211	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HEGBPLAD_01525	2.63e-71	nudA	-	-	S	-	-	-	ASCH
HEGBPLAD_01526	9.94e-101	-	-	-	S	-	-	-	SdpI/YhfL protein family
HEGBPLAD_01527	5.02e-129	-	-	-	M	-	-	-	Lysin motif
HEGBPLAD_01528	2.72e-316	hpk2	-	-	T	-	-	-	Histidine kinase
HEGBPLAD_01529	6.35e-164	rrp2	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HEGBPLAD_01530	2.42e-65	-	-	-	-	-	-	-	-
HEGBPLAD_01531	1.96e-167	yidA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HEGBPLAD_01532	1.73e-306	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEGBPLAD_01533	3.35e-75	-	-	-	-	-	-	-	-
HEGBPLAD_01534	2.14e-46	-	-	-	-	-	-	-	-
HEGBPLAD_01535	7.18e-236	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HEGBPLAD_01536	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HEGBPLAD_01537	1.49e-63	-	-	-	-	-	-	-	-
HEGBPLAD_01538	1.18e-157	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HEGBPLAD_01539	1.17e-135	-	-	-	K	-	-	-	transcriptional regulator
HEGBPLAD_01540	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HEGBPLAD_01541	7.98e-137	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HEGBPLAD_01542	1.6e-226	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HEGBPLAD_01543	1.42e-212	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HEGBPLAD_01544	3.22e-289	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HEGBPLAD_01545	1.63e-154	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HEGBPLAD_01546	4.6e-171	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HEGBPLAD_01547	5.73e-143	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HEGBPLAD_01548	2.05e-75	-	-	-	M	-	-	-	Lysin motif
HEGBPLAD_01549	1e-302	-	-	-	M	-	-	-	domain protein
HEGBPLAD_01550	2.1e-87	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
HEGBPLAD_01551	5.53e-120	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
HEGBPLAD_01552	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HEGBPLAD_01553	1.15e-23	-	-	-	S	-	-	-	NUDIX domain
HEGBPLAD_01554	0.0	-	-	-	S	-	-	-	membrane
HEGBPLAD_01555	2.02e-216	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HEGBPLAD_01556	1.76e-110	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HEGBPLAD_01557	6.96e-283	ribA	3.5.4.25, 4.1.99.12	-	H	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HEGBPLAD_01558	5.38e-105	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HEGBPLAD_01559	1.65e-55	-	-	-	K	-	-	-	transcriptional regulator
HEGBPLAD_01560	3.67e-79	-	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
HEGBPLAD_01561	3.39e-138	-	-	-	-	-	-	-	-
HEGBPLAD_01562	1.83e-148	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HEGBPLAD_01563	1.64e-144	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HEGBPLAD_01564	4.08e-306	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HEGBPLAD_01565	0.0	-	-	-	-	-	-	-	-
HEGBPLAD_01566	2.22e-126	-	-	-	-	-	-	-	-
HEGBPLAD_01567	3.75e-77	-	-	-	-	-	-	-	-
HEGBPLAD_01568	2.27e-246	-	-	-	S	-	-	-	Fn3-like domain
HEGBPLAD_01569	6.93e-139	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HEGBPLAD_01570	1.65e-134	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HEGBPLAD_01571	2.1e-194	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HEGBPLAD_01572	4.76e-73	-	-	-	-	-	-	-	-
HEGBPLAD_01573	3.6e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HEGBPLAD_01574	7.42e-173	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEGBPLAD_01575	1.35e-283	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HEGBPLAD_01576	7.24e-197	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
HEGBPLAD_01577	2.8e-155	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HEGBPLAD_01578	2.94e-71	ytzB	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HEGBPLAD_01579	1.51e-147	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEGBPLAD_01580	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HEGBPLAD_01581	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HEGBPLAD_01582	7.19e-28	-	-	-	S	-	-	-	Virus attachment protein p12 family
HEGBPLAD_01583	7.2e-195	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HEGBPLAD_01584	1.69e-61	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HEGBPLAD_01585	6.61e-174	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HEGBPLAD_01586	2.87e-47	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
HEGBPLAD_01587	1.28e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HEGBPLAD_01588	6.07e-310	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HEGBPLAD_01589	7.46e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HEGBPLAD_01590	1.1e-107	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HEGBPLAD_01591	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HEGBPLAD_01592	3.33e-243	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HEGBPLAD_01593	2.68e-176	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HEGBPLAD_01594	7.99e-212	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEGBPLAD_01595	1.11e-105	-	-	-	C	-	-	-	Flavodoxin
HEGBPLAD_01596	1.89e-90	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
HEGBPLAD_01597	7.86e-46	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
HEGBPLAD_01598	1.87e-246	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HEGBPLAD_01599	3.95e-181	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Transporter, major facilitator family protein
HEGBPLAD_01600	1.71e-76	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Transporter, major facilitator family protein
HEGBPLAD_01601	4.08e-78	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HEGBPLAD_01602	1.29e-201	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HEGBPLAD_01603	3.54e-53	-	-	-	H	-	-	-	geranyltranstransferase activity
HEGBPLAD_01604	2.83e-127	-	-	-	H	-	-	-	geranyltranstransferase activity
HEGBPLAD_01605	1.24e-232	-	-	-	-	-	-	-	-
HEGBPLAD_01606	3.67e-65	-	-	-	-	-	-	-	-
HEGBPLAD_01607	4.49e-151	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
HEGBPLAD_01608	2.01e-242	nreB	2.7.13.3	-	F	ko:K07683	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
HEGBPLAD_01609	1.48e-98	-	2.7.13.3	-	T	ko:K07683,ko:K10851	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	phosphoenolpyruvate-protein phosphotransferase activity
HEGBPLAD_01610	8.84e-52	-	-	-	-	-	-	-	-
HEGBPLAD_01611	4.71e-128	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HEGBPLAD_01612	6.28e-111	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HEGBPLAD_01613	2.65e-113	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
HEGBPLAD_01614	3.51e-292	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA N-terminal region (domain I and II)
HEGBPLAD_01615	1.91e-108	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
HEGBPLAD_01616	1.31e-243	moeB	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
HEGBPLAD_01617	0.0	narZ	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEGBPLAD_01618	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
HEGBPLAD_01619	1.93e-125	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	Nitrate reductase delta subunit
HEGBPLAD_01620	2.58e-156	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
HEGBPLAD_01621	3.37e-223	-	-	-	-	-	-	-	-
HEGBPLAD_01622	4.4e-97	-	-	-	-	-	-	-	-
HEGBPLAD_01623	3.76e-114	-	-	-	S	-	-	-	Protein of unknown function (DUF2975)
HEGBPLAD_01624	6.66e-39	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
HEGBPLAD_01625	2.44e-154	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HEGBPLAD_01626	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HEGBPLAD_01627	3.19e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HEGBPLAD_01628	6.44e-132	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HEGBPLAD_01629	1.58e-117	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HEGBPLAD_01630	1.61e-315	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HEGBPLAD_01631	6.05e-221	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HEGBPLAD_01632	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HEGBPLAD_01633	2.37e-109	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HEGBPLAD_01634	6.92e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HEGBPLAD_01635	6.88e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HEGBPLAD_01638	1.68e-23	-	-	-	-	-	-	-	-
HEGBPLAD_01639	5.77e-306	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
HEGBPLAD_01640	7.94e-249	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HEGBPLAD_01641	3.3e-83	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HEGBPLAD_01642	5.38e-80	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HEGBPLAD_01643	8.9e-53	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HEGBPLAD_01644	1.9e-316	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HEGBPLAD_01645	6.32e-114	-	-	-	-	-	-	-	-
HEGBPLAD_01646	2.32e-126	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HEGBPLAD_01647	3.81e-276	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HEGBPLAD_01648	2.19e-67	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HEGBPLAD_01649	4.19e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HEGBPLAD_01650	1.71e-149	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HEGBPLAD_01651	1.06e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HEGBPLAD_01652	3.85e-179	yqeM	-	-	Q	-	-	-	Methyltransferase
HEGBPLAD_01653	1.76e-279	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HEGBPLAD_01654	3.66e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HEGBPLAD_01655	7.2e-123	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HEGBPLAD_01656	4.51e-129	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEGBPLAD_01657	2.05e-65	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEGBPLAD_01658	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HEGBPLAD_01659	8.5e-130	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HEGBPLAD_01660	3.4e-162	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HEGBPLAD_01661	1.38e-155	csrR	-	-	K	-	-	-	response regulator
HEGBPLAD_01662	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEGBPLAD_01663	1.21e-27	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HEGBPLAD_01664	2.31e-202	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HEGBPLAD_01665	1.88e-75	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HEGBPLAD_01666	6.52e-96	-	-	-	-	-	-	-	-
HEGBPLAD_01667	1.77e-103	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HEGBPLAD_01668	8.96e-275	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HEGBPLAD_01669	2.58e-230	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HEGBPLAD_01670	7.88e-211	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HEGBPLAD_01671	1.89e-12	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
HEGBPLAD_01672	2.21e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HEGBPLAD_01673	4.15e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEGBPLAD_01674	1.55e-225	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HEGBPLAD_01675	2.32e-237	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HEGBPLAD_01676	1.97e-72	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HEGBPLAD_01677	4.26e-105	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
HEGBPLAD_01678	1.16e-12	-	-	-	-	ko:K02671	-	ko00000,ko02035,ko02044	-
HEGBPLAD_01679	5.3e-112	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
HEGBPLAD_01681	1.28e-235	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HEGBPLAD_01682	9.09e-280	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HEGBPLAD_01683	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HEGBPLAD_01684	5.77e-151	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HEGBPLAD_01685	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HEGBPLAD_01686	5.6e-116	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HEGBPLAD_01687	5.9e-188	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HEGBPLAD_01688	4.69e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HEGBPLAD_01689	7.18e-153	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HEGBPLAD_01690	5.16e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HEGBPLAD_01691	1.16e-97	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	general stress protein
HEGBPLAD_01692	4.2e-83	nox	-	-	C	-	-	-	NADH oxidase
HEGBPLAD_01693	3.7e-28	nox	-	-	C	-	-	-	NADH oxidase
HEGBPLAD_01694	6.37e-160	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HEGBPLAD_01695	1.13e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HEGBPLAD_01696	1.15e-234	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HEGBPLAD_01697	1.04e-211	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HEGBPLAD_01698	3.81e-226	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HEGBPLAD_01699	2.87e-71	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HEGBPLAD_01700	2.78e-65	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
HEGBPLAD_01701	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HEGBPLAD_01702	2.31e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEGBPLAD_01703	9.78e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEGBPLAD_01704	5.04e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HEGBPLAD_01705	2.22e-206	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HEGBPLAD_01706	1.63e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HEGBPLAD_01707	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEGBPLAD_01708	1.49e-170	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HEGBPLAD_01709	1.28e-276	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HEGBPLAD_01710	9.78e-257	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HEGBPLAD_01711	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HEGBPLAD_01712	1.27e-129	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HEGBPLAD_01713	2.41e-163	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HEGBPLAD_01714	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HEGBPLAD_01715	5.25e-149	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HEGBPLAD_01716	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HEGBPLAD_01717	7.27e-303	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HEGBPLAD_01718	1.34e-52	-	-	-	-	-	-	-	-
HEGBPLAD_01719	2.37e-107	uspA	-	-	T	-	-	-	universal stress protein
HEGBPLAD_01720	1.37e-252	bla2	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HEGBPLAD_01721	1.57e-205	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEGBPLAD_01722	0.0	glpQ3	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HEGBPLAD_01723	1.08e-271	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HEGBPLAD_01724	2.53e-240	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HEGBPLAD_01725	6.58e-227	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HEGBPLAD_01726	3.34e-215	hicD3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HEGBPLAD_01727	3.03e-191	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HEGBPLAD_01728	2.1e-151	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HEGBPLAD_01729	2.24e-239	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HEGBPLAD_01730	3.2e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
HEGBPLAD_01731	2.15e-280	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HEGBPLAD_01732	2.54e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HEGBPLAD_01733	5.3e-58	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HEGBPLAD_01734	1.44e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HEGBPLAD_01735	1.96e-131	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HEGBPLAD_01736	5.88e-315	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEGBPLAD_01737	1.33e-77	-	-	-	-	-	-	-	-
HEGBPLAD_01738	1.9e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HEGBPLAD_01739	2.1e-41	-	-	-	-	-	-	-	-
HEGBPLAD_01740	1.12e-246	ampC	-	-	V	-	-	-	Beta-lactamase
HEGBPLAD_01741	4.95e-250	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HEGBPLAD_01742	1.24e-173	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HEGBPLAD_01743	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
HEGBPLAD_01744	5e-141	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HEGBPLAD_01745	2.67e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HEGBPLAD_01746	1.64e-202	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HEGBPLAD_01747	1.21e-241	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HEGBPLAD_01748	8.34e-295	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HEGBPLAD_01749	7.81e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HEGBPLAD_01750	2.49e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HEGBPLAD_01751	4.82e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HEGBPLAD_01752	1.81e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEGBPLAD_01753	2.42e-80	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HEGBPLAD_01754	2.03e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEGBPLAD_01755	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HEGBPLAD_01756	1.3e-212	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HEGBPLAD_01757	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HEGBPLAD_01758	5.95e-74	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HEGBPLAD_01759	1.52e-76	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HEGBPLAD_01760	1.54e-116	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEGBPLAD_01761	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HEGBPLAD_01763	1.41e-215	-	-	-	EG	-	-	-	EamA-like transporter family
HEGBPLAD_01764	6.12e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HEGBPLAD_01765	2.12e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HEGBPLAD_01766	1.45e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HEGBPLAD_01767	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HEGBPLAD_01768	1.83e-277	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HEGBPLAD_01769	2.51e-200	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HEGBPLAD_01770	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HEGBPLAD_01771	2.1e-33	-	-	-	-	-	-	-	-
HEGBPLAD_01772	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEGBPLAD_01773	3.99e-300	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HEGBPLAD_01774	1.19e-14	-	3.6.3.44	-	P	ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
HEGBPLAD_01775	0.0	-	3.6.3.44	-	P	ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
HEGBPLAD_01776	4.63e-24	-	-	-	-	-	-	-	-
HEGBPLAD_01777	2.16e-26	-	-	-	-	-	-	-	-
HEGBPLAD_01778	1.56e-22	-	-	-	-	-	-	-	-
HEGBPLAD_01779	3.26e-24	-	-	-	-	-	-	-	-
HEGBPLAD_01780	4.53e-146	gph3	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HEGBPLAD_01781	5.26e-247	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
HEGBPLAD_01782	8.37e-296	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HEGBPLAD_01783	6e-60	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HEGBPLAD_01784	2.7e-104	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HEGBPLAD_01785	1.76e-160	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
HEGBPLAD_01786	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HEGBPLAD_01787	4.09e-92	yueI	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HEGBPLAD_01788	3.95e-132	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HEGBPLAD_01789	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HEGBPLAD_01790	3.55e-174	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HEGBPLAD_01791	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
HEGBPLAD_01792	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEGBPLAD_01793	1.4e-261	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
HEGBPLAD_01794	3.76e-180	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HEGBPLAD_01795	2.64e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HEGBPLAD_01796	8.52e-209	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HEGBPLAD_01797	4.96e-173	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HEGBPLAD_01798	0.0	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEGBPLAD_01799	1.34e-261	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HEGBPLAD_01800	4.35e-23	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HEGBPLAD_01801	2.46e-172	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HEGBPLAD_01802	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HEGBPLAD_01803	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HEGBPLAD_01804	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HEGBPLAD_01805	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HEGBPLAD_01806	1.95e-140	aqpZ	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HEGBPLAD_01807	9.49e-282	-	-	-	S	-	-	-	associated with various cellular activities
HEGBPLAD_01808	3.42e-313	-	-	-	S	-	-	-	Putative metallopeptidase domain
HEGBPLAD_01809	1.03e-65	-	-	-	-	-	-	-	-
HEGBPLAD_01810	1.72e-135	yezE	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
HEGBPLAD_01811	4.54e-59	-	-	-	-	-	-	-	-
HEGBPLAD_01812	4.94e-128	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HEGBPLAD_01813	9.71e-157	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HEGBPLAD_01814	1.24e-233	-	-	-	S	-	-	-	Cell surface protein
HEGBPLAD_01815	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HEGBPLAD_01816	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HEGBPLAD_01817	8.68e-106	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HEGBPLAD_01818	3.7e-84	-	-	-	M	-	-	-	LysM domain protein
HEGBPLAD_01819	4.2e-88	gcsH1	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Glycine cleavage H-protein
HEGBPLAD_01820	2.04e-225	-	-	-	-	-	-	-	-
HEGBPLAD_01821	2.17e-151	-	-	-	-	-	-	-	-
HEGBPLAD_01822	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
HEGBPLAD_01823	3.95e-71	-	-	-	-	-	-	-	-
HEGBPLAD_01824	3.07e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HEGBPLAD_01825	7.61e-102	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HEGBPLAD_01826	1.24e-99	-	-	-	K	-	-	-	Transcriptional regulator
HEGBPLAD_01827	1.17e-288	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HEGBPLAD_01828	8.88e-53	-	-	-	-	-	-	-	-
HEGBPLAD_01829	3.07e-264	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HEGBPLAD_01830	9.24e-180	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HEGBPLAD_01831	3.14e-190	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HEGBPLAD_01832	1.46e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HEGBPLAD_01833	2.13e-124	-	-	-	K	-	-	-	Cupin domain
HEGBPLAD_01834	3.85e-108	-	-	-	S	-	-	-	ASCH
HEGBPLAD_01835	7.36e-109	-	-	-	K	-	-	-	GNAT family
HEGBPLAD_01836	2.05e-115	-	-	-	K	-	-	-	acetyltransferase
HEGBPLAD_01837	2.06e-30	-	-	-	-	-	-	-	-
HEGBPLAD_01838	5.05e-79	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HEGBPLAD_01839	3.07e-207	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HEGBPLAD_01840	1.27e-309	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HEGBPLAD_01841	1.75e-172	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HEGBPLAD_01842	2.79e-233	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HEGBPLAD_01843	8.66e-152	-	-	-	K	-	-	-	Transcriptional regulator
HEGBPLAD_01844	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HEGBPLAD_01845	6.2e-114	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
HEGBPLAD_01846	1.66e-287	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HEGBPLAD_01847	9.59e-289	-	-	-	S	-	-	-	Sterol carrier protein domain
HEGBPLAD_01848	6.01e-270	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HEGBPLAD_01849	3.94e-49	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
HEGBPLAD_01850	1.89e-172	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HEGBPLAD_01851	2.26e-91	-	-	-	FG	-	-	-	Scavenger mRNA decapping enzyme C-term binding
HEGBPLAD_01852	2.19e-130	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HEGBPLAD_01853	1.76e-143	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HEGBPLAD_01854	2.99e-38	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
HEGBPLAD_01855	4.46e-184	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HEGBPLAD_01856	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HEGBPLAD_01857	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HEGBPLAD_01858	7.09e-178	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
HEGBPLAD_01859	4.41e-155	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HEGBPLAD_01860	1.1e-123	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HEGBPLAD_01861	1.27e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HEGBPLAD_01862	1.52e-239	-	-	-	S	-	-	-	Cell surface protein
HEGBPLAD_01863	2.84e-82	-	-	-	-	-	-	-	-
HEGBPLAD_01864	0.0	-	-	-	-	-	-	-	-
HEGBPLAD_01865	7.28e-218	XK27_00670	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HEGBPLAD_01866	2.63e-194	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HEGBPLAD_01867	2.33e-140	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HEGBPLAD_01868	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HEGBPLAD_01869	8.08e-154	ydgI3	-	-	C	-	-	-	Nitroreductase family
HEGBPLAD_01870	9.06e-125	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HEGBPLAD_01871	1.22e-61	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HEGBPLAD_01872	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HEGBPLAD_01873	1.43e-195	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HEGBPLAD_01877	1.28e-214	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HEGBPLAD_01878	7.45e-179	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HEGBPLAD_01879	9.69e-99	-	-	-	-	-	-	-	-
HEGBPLAD_01880	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HEGBPLAD_01881	3.99e-179	-	-	-	-	-	-	-	-
HEGBPLAD_01882	4.07e-05	-	-	-	-	-	-	-	-
HEGBPLAD_01883	3.82e-182	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HEGBPLAD_01884	1.67e-54	-	-	-	-	-	-	-	-
HEGBPLAD_01885	4.29e-166	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HEGBPLAD_01886	9.79e-192	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HEGBPLAD_01887	3.71e-235	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
HEGBPLAD_01888	1.39e-156	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
HEGBPLAD_01889	7.9e-306	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
HEGBPLAD_01890	2.14e-157	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
HEGBPLAD_01891	2.03e-179	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HEGBPLAD_01892	6.32e-99	larC2	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Protein of unknown function DUF111
HEGBPLAD_01893	1.19e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HEGBPLAD_01894	3.69e-193	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
HEGBPLAD_01895	6.81e-225	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HEGBPLAD_01896	1.53e-174	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HEGBPLAD_01897	1.18e-188	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HEGBPLAD_01898	1.09e-142	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HEGBPLAD_01899	1.69e-260	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HEGBPLAD_01900	3.54e-176	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HEGBPLAD_01901	0.0	-	-	-	L	-	-	-	HIRAN domain
HEGBPLAD_01902	7.17e-109	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HEGBPLAD_01903	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HEGBPLAD_01904	1.73e-157	-	-	-	-	-	-	-	-
HEGBPLAD_01905	5.08e-192	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HEGBPLAD_01906	0.0	pacL1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HEGBPLAD_01907	1.19e-37	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HEGBPLAD_01908	9.54e-140	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HEGBPLAD_01909	4.27e-97	-	-	-	K	-	-	-	Transcriptional regulator
HEGBPLAD_01910	3.99e-96	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HEGBPLAD_01911	1.07e-103	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HEGBPLAD_01912	3.01e-86	-	-	-	K	-	-	-	LytTr DNA-binding domain
HEGBPLAD_01913	2.19e-289	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HEGBPLAD_01914	6.6e-67	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HEGBPLAD_01915	4.62e-273	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HEGBPLAD_01917	5.7e-200	morA	-	-	S	-	-	-	reductase
HEGBPLAD_01918	9.59e-212	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo keto reductase
HEGBPLAD_01919	7.84e-106	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase like
HEGBPLAD_01920	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HEGBPLAD_01921	9.08e-110	-	-	-	-	-	-	-	-
HEGBPLAD_01922	0.0	-	-	-	-	-	-	-	-
HEGBPLAD_01923	2.53e-265	-	-	-	C	-	-	-	Oxidoreductase
HEGBPLAD_01924	3.28e-193	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HEGBPLAD_01925	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HEGBPLAD_01926	5.18e-128	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HEGBPLAD_01928	4.37e-167	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HEGBPLAD_01929	4.14e-72	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HEGBPLAD_01930	2.12e-180	-	-	-	-	-	-	-	-
HEGBPLAD_01931	1.83e-190	-	-	-	-	-	-	-	-
HEGBPLAD_01932	3.37e-115	-	-	-	-	-	-	-	-
HEGBPLAD_01933	7.14e-185	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HEGBPLAD_01934	1.42e-216	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HEGBPLAD_01935	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
HEGBPLAD_01936	8.03e-151	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HEGBPLAD_01937	0.0	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
HEGBPLAD_01938	1.18e-98	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HEGBPLAD_01940	1.85e-121	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HEGBPLAD_01941	1.77e-238	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
HEGBPLAD_01942	2.62e-237	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
HEGBPLAD_01943	1.59e-130	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
HEGBPLAD_01944	6.76e-75	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
HEGBPLAD_01945	2.32e-171	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HEGBPLAD_01946	1.08e-244	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HEGBPLAD_01947	1.83e-231	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HEGBPLAD_01948	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HEGBPLAD_01949	9.45e-299	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HEGBPLAD_01950	3.07e-301	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HEGBPLAD_01951	2.83e-206	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HEGBPLAD_01952	1.01e-190	malA	-	-	S	-	-	-	maltodextrose utilization protein MalA
HEGBPLAD_01953	0.0	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
HEGBPLAD_01954	3.33e-265	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEGBPLAD_01955	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HEGBPLAD_01956	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
HEGBPLAD_01957	8.23e-61	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HEGBPLAD_01958	2.98e-214	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HEGBPLAD_01959	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEGBPLAD_01960	7.69e-214	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HEGBPLAD_01961	1.62e-72	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
HEGBPLAD_01962	3.66e-96	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
HEGBPLAD_01963	8.75e-30	-	2.3.1.128	-	J	ko:K03789	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HEGBPLAD_01964	1.04e-94	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HEGBPLAD_01965	1.1e-93	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HEGBPLAD_01966	5.74e-32	-	-	-	-	-	-	-	-
HEGBPLAD_01967	3.23e-115	-	-	-	-	-	-	-	-
HEGBPLAD_01968	1.81e-50	ydaS	-	-	S	-	-	-	Transglycosylase associated protein
HEGBPLAD_01969	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase family
HEGBPLAD_01970	2.09e-60	-	-	-	S	-	-	-	MORN repeat
HEGBPLAD_01971	5.24e-61	-	-	-	-	-	-	-	-
HEGBPLAD_01972	1.29e-162	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HEGBPLAD_01973	2.97e-100	-	-	-	-	-	-	-	-
HEGBPLAD_01974	8.44e-103	-	-	-	D	-	-	-	nuclear chromosome segregation
HEGBPLAD_01975	7.08e-24	-	-	-	D	-	-	-	nuclear chromosome segregation
HEGBPLAD_01976	1.59e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HEGBPLAD_01977	9.57e-239	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HEGBPLAD_01978	5.01e-50	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HEGBPLAD_01979	1.36e-301	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
HEGBPLAD_01980	1.07e-74	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HEGBPLAD_01981	2.85e-145	XK27_07075	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HEGBPLAD_01982	5.98e-302	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HEGBPLAD_01983	1.02e-63	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HEGBPLAD_01984	4.86e-234	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HEGBPLAD_01985	1.15e-161	-	-	-	S	-	-	-	DJ-1/PfpI family
HEGBPLAD_01986	8.6e-118	yfbM	-	-	K	-	-	-	FR47-like protein
HEGBPLAD_01987	8.64e-195	-	-	-	EG	-	-	-	EamA-like transporter family
HEGBPLAD_01988	3.29e-163	-	-	-	S	-	-	-	Protein of unknown function
HEGBPLAD_01989	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HEGBPLAD_01990	1.91e-151	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HEGBPLAD_01991	1.04e-216	-	-	-	K	-	-	-	WYL domain
HEGBPLAD_01992	6.17e-165	-	-	-	F	-	-	-	glutamine amidotransferase
HEGBPLAD_01993	3.21e-104	-	-	-	S	-	-	-	ASCH
HEGBPLAD_01994	3.29e-174	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HEGBPLAD_01995	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HEGBPLAD_01996	3.11e-248	pva1	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HEGBPLAD_01997	1.1e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HEGBPLAD_01998	1.25e-183	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HEGBPLAD_01999	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HEGBPLAD_02000	2.59e-152	rcfA	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HEGBPLAD_02001	3.38e-44	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
HEGBPLAD_02002	1.67e-123	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HEGBPLAD_02003	1.01e-26	-	-	-	-	-	-	-	-
HEGBPLAD_02004	4.82e-55	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
HEGBPLAD_02005	2.34e-72	trxA3	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
HEGBPLAD_02006	5.24e-180	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HEGBPLAD_02007	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HEGBPLAD_02008	2.02e-22	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HEGBPLAD_02009	5.16e-190	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HEGBPLAD_02010	8.35e-163	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
HEGBPLAD_02011	4.16e-175	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HEGBPLAD_02012	1.24e-232	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HEGBPLAD_02013	2.55e-131	-	-	-	K	-	-	-	transcriptional regulator
HEGBPLAD_02014	2.67e-203	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
HEGBPLAD_02015	5.17e-70	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
HEGBPLAD_02016	2.44e-136	-	-	-	-	-	-	-	-
HEGBPLAD_02017	2.64e-13	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HEGBPLAD_02019	3.16e-25	-	-	-	-	-	-	-	-
HEGBPLAD_02021	2.22e-131	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEGBPLAD_02022	1.07e-206	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HEGBPLAD_02023	1.47e-72	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HEGBPLAD_02024	2.94e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HEGBPLAD_02025	1.97e-60	qacH	-	-	U	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HEGBPLAD_02026	1.15e-77	-	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HEGBPLAD_02027	6.83e-276	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HEGBPLAD_02028	1.54e-228	ydbI	-	-	K	-	-	-	AI-2E family transporter
HEGBPLAD_02029	2.51e-210	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEGBPLAD_02030	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HEGBPLAD_02032	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
HEGBPLAD_02033	3.25e-107	-	-	-	-	-	-	-	-
HEGBPLAD_02034	2.74e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HEGBPLAD_02035	4.9e-188	-	-	-	S	ko:K01421	-	ko00000	ABC-2 family transporter protein
HEGBPLAD_02036	2.61e-60	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HEGBPLAD_02037	6.42e-89	-	-	-	K	-	-	-	LysR substrate binding domain
HEGBPLAD_02038	3.52e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
HEGBPLAD_02039	5.46e-145	pgm8	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
HEGBPLAD_02040	2.81e-64	-	-	-	-	-	-	-	-
HEGBPLAD_02041	9.76e-50	-	-	-	-	-	-	-	-
HEGBPLAD_02042	2.97e-110	yvbK	-	-	K	-	-	-	GNAT family
HEGBPLAD_02043	1.39e-110	-	-	-	-	-	-	-	-
HEGBPLAD_02044	4.35e-144	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HEGBPLAD_02045	1.03e-150	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HEGBPLAD_02046	1.06e-139	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HEGBPLAD_02047	1.69e-150	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HEGBPLAD_02049	1.74e-156	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEGBPLAD_02050	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HEGBPLAD_02051	1.7e-298	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HEGBPLAD_02053	3.54e-61	-	-	-	H	-	-	-	RibD C-terminal domain
HEGBPLAD_02054	2.12e-102	-	-	-	K	-	-	-	transcriptional regulator, MerR family
HEGBPLAD_02055	4.77e-100	yphH	-	-	S	-	-	-	Cupin domain
HEGBPLAD_02056	4.72e-72	cmd	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HEGBPLAD_02057	3.63e-165	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HEGBPLAD_02058	7.88e-269	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HEGBPLAD_02059	9.97e-214	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEGBPLAD_02060	3.18e-201	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
HEGBPLAD_02061	1.01e-176	yceF	-	-	P	ko:K05794	-	ko00000	membrane
HEGBPLAD_02062	4.99e-125	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HEGBPLAD_02063	9.05e-257	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HEGBPLAD_02064	1.07e-68	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
HEGBPLAD_02065	2.05e-76	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HEGBPLAD_02066	7.23e-154	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HEGBPLAD_02067	1.96e-165	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HEGBPLAD_02068	6.4e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HEGBPLAD_02069	8.22e-138	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HEGBPLAD_02070	2.61e-297	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HEGBPLAD_02071	4.21e-100	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HEGBPLAD_02072	1.81e-272	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HEGBPLAD_02073	3.74e-207	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
HEGBPLAD_02074	3.05e-282	ysaA	-	-	V	-	-	-	RDD family
HEGBPLAD_02075	7.28e-213	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HEGBPLAD_02076	6.96e-67	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HEGBPLAD_02077	1.12e-25	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
HEGBPLAD_02078	1.14e-253	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HEGBPLAD_02079	1.35e-236	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HEGBPLAD_02091	1.05e-115	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
HEGBPLAD_02092	2.48e-234	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
HEGBPLAD_02093	1.2e-122	-	-	-	-	-	-	-	-
HEGBPLAD_02094	1.58e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HEGBPLAD_02095	2.07e-200	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HEGBPLAD_02097	8.01e-294	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HEGBPLAD_02098	7.25e-240	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HEGBPLAD_02099	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HEGBPLAD_02100	5.32e-214	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HEGBPLAD_02101	1.33e-144	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HEGBPLAD_02102	1.08e-198	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HEGBPLAD_02103	5.79e-158	-	-	-	-	-	-	-	-
HEGBPLAD_02104	1.13e-272	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HEGBPLAD_02105	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
HEGBPLAD_02106	0.0	-	-	-	M	-	-	-	domain protein
HEGBPLAD_02108	1.03e-201	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HEGBPLAD_02109	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HEGBPLAD_02110	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HEGBPLAD_02111	4.4e-101	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HEGBPLAD_02112	1.45e-278	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEGBPLAD_02113	1.24e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HEGBPLAD_02114	2.73e-147	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
HEGBPLAD_02115	1.01e-228	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HEGBPLAD_02116	6.33e-46	-	-	-	-	-	-	-	-
HEGBPLAD_02117	2.32e-79	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HEGBPLAD_02118	1.53e-208	fbpA	-	-	K	-	-	-	Domain of unknown function (DUF814)
HEGBPLAD_02119	7.45e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HEGBPLAD_02120	3.81e-18	-	-	-	-	-	-	-	-
HEGBPLAD_02121	1.51e-73	-	-	-	-	-	-	-	-
HEGBPLAD_02122	2.43e-103	accB3	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HEGBPLAD_02123	6.07e-223	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HEGBPLAD_02124	1.03e-206	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HEGBPLAD_02125	0.0	-	-	-	-	-	-	-	-
HEGBPLAD_02126	7.88e-100	-	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
HEGBPLAD_02127	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HEGBPLAD_02128	7.73e-230	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HEGBPLAD_02129	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulphide oxidoreductase
HEGBPLAD_02130	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HEGBPLAD_02131	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
HEGBPLAD_02132	1.14e-62	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HEGBPLAD_02133	7.22e-95	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HEGBPLAD_02134	2.26e-220	-	-	-	M	-	-	-	domain protein
HEGBPLAD_02136	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEGBPLAD_02137	2.69e-183	ptp2	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HEGBPLAD_02138	4.17e-235	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HEGBPLAD_02139	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HEGBPLAD_02140	3.03e-314	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HEGBPLAD_02141	2.05e-72	-	-	-	S	-	-	-	Enterocin A Immunity
HEGBPLAD_02142	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HEGBPLAD_02143	1.17e-250	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HEGBPLAD_02144	1.76e-230	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
HEGBPLAD_02145	2.74e-208	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
HEGBPLAD_02146	2.65e-104	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
HEGBPLAD_02147	5.32e-43	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
HEGBPLAD_02148	3.18e-156	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
HEGBPLAD_02149	1.48e-152	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
HEGBPLAD_02150	3.24e-11	-	-	-	L	-	-	-	Transposase domain (DUF772)
HEGBPLAD_02151	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HEGBPLAD_02152	9.51e-120	-	-	-	T	-	-	-	EAL domain
HEGBPLAD_02153	5.43e-188	-	3.1.3.23	-	S	ko:K07757	-	ko00000,ko01000	Sucrose-6F-phosphate phosphohydrolase
HEGBPLAD_02154	9.56e-133	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HEGBPLAD_02155	1.7e-262	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HEGBPLAD_02156	3.38e-70	-	-	-	-	-	-	-	-
HEGBPLAD_02157	4.14e-94	-	-	-	-	-	-	-	-
HEGBPLAD_02158	3.35e-167	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HEGBPLAD_02159	6.26e-177	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HEGBPLAD_02160	2.12e-17	-	-	-	G	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HEGBPLAD_02161	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HEGBPLAD_02162	4.41e-159	-	-	-	-	-	-	-	-
HEGBPLAD_02164	5.45e-94	spx1	-	-	P	ko:K16509	-	ko00000	ArsC family
HEGBPLAD_02165	5.51e-46	-	-	-	-	-	-	-	-
HEGBPLAD_02166	2.08e-117	-	-	-	V	-	-	-	VanZ like family
HEGBPLAD_02167	5.4e-310	-	-	-	EGP	-	-	-	Major Facilitator
HEGBPLAD_02168	1.49e-224	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HEGBPLAD_02169	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HEGBPLAD_02170	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HEGBPLAD_02171	7.8e-196	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HEGBPLAD_02172	6.16e-107	-	-	-	K	-	-	-	Transcriptional regulator
HEGBPLAD_02173	1.36e-27	-	-	-	-	-	-	-	-
HEGBPLAD_02174	1.79e-287	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HEGBPLAD_02175	1.79e-285	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HEGBPLAD_02176	1.71e-113	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HEGBPLAD_02177	1.29e-196	ribC1	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HEGBPLAD_02178	0.0	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HEGBPLAD_02179	6.81e-82	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HEGBPLAD_02180	3.45e-231	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HEGBPLAD_02181	1.23e-229	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HEGBPLAD_02182	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HEGBPLAD_02183	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HEGBPLAD_02184	1.89e-90	-	-	-	O	-	-	-	OsmC-like protein
HEGBPLAD_02185	3.8e-61	-	-	-	-	-	-	-	-
HEGBPLAD_02186	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HEGBPLAD_02187	5.04e-114	-	-	-	-	-	-	-	-
HEGBPLAD_02188	2.49e-189	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HEGBPLAD_02189	7.48e-96	-	-	-	F	-	-	-	Nudix hydrolase
HEGBPLAD_02190	1.48e-27	-	-	-	-	-	-	-	-
HEGBPLAD_02191	2.45e-134	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HEGBPLAD_02192	2.02e-106	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HEGBPLAD_02193	9.37e-18	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HEGBPLAD_02194	5.86e-188	-	-	-	-	-	-	-	-
HEGBPLAD_02196	6.94e-146	gph1	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant
HEGBPLAD_02197	3.92e-269	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HEGBPLAD_02198	5.94e-217	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEGBPLAD_02199	1.28e-54	-	-	-	-	-	-	-	-
HEGBPLAD_02201	2.3e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HEGBPLAD_02202	3.39e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HEGBPLAD_02203	3.14e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HEGBPLAD_02204	1.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HEGBPLAD_02205	2.46e-108	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HEGBPLAD_02206	4.68e-198	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HEGBPLAD_02207	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HEGBPLAD_02208	2.22e-182	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
HEGBPLAD_02209	5.89e-313	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HEGBPLAD_02210	6.02e-94	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEGBPLAD_02211	1.03e-189	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
HEGBPLAD_02212	3.08e-93	-	-	-	K	-	-	-	MarR family
HEGBPLAD_02213	6.96e-264	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HEGBPLAD_02214	2.93e-109	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HEGBPLAD_02215	7.36e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HEGBPLAD_02216	1.7e-299	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HEGBPLAD_02217	4.6e-102	rppH3	-	-	F	-	-	-	NUDIX domain
HEGBPLAD_02218	4.97e-64	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
HEGBPLAD_02219	1.61e-36	-	-	-	-	-	-	-	-
HEGBPLAD_02220	6.4e-164	pgm3	-	-	G	-	-	-	Phosphoglycerate mutase family
HEGBPLAD_02221	2.07e-161	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
HEGBPLAD_02222	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HEGBPLAD_02223	4.85e-226	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HEGBPLAD_02224	1.64e-145	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HEGBPLAD_02225	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HEGBPLAD_02226	5.7e-209	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
HEGBPLAD_02227	1.22e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HEGBPLAD_02228	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HEGBPLAD_02229	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HEGBPLAD_02230	4.37e-128	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HEGBPLAD_02231	6.07e-33	-	-	-	-	-	-	-	-
HEGBPLAD_02232	0.0	-	-	-	S	ko:K06889	-	ko00000	Alpha beta
HEGBPLAD_02233	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HEGBPLAD_02234	7.76e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HEGBPLAD_02235	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HEGBPLAD_02236	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HEGBPLAD_02237	8.95e-207	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HEGBPLAD_02238	6.06e-233	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HEGBPLAD_02239	8.5e-213	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HEGBPLAD_02241	0.0	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
HEGBPLAD_02242	2.84e-222	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
HEGBPLAD_02243	2.62e-145	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HEGBPLAD_02244	5.77e-289	sat	2.7.7.4	-	H	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HEGBPLAD_02245	2.69e-285	-	-	-	S	-	-	-	Protein conserved in bacteria
HEGBPLAD_02246	2.4e-82	-	-	-	S	-	-	-	Protein conserved in bacteria
HEGBPLAD_02247	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HEGBPLAD_02248	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HEGBPLAD_02249	8.01e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
HEGBPLAD_02250	4.91e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
HEGBPLAD_02251	3.89e-237	-	-	-	-	-	-	-	-
HEGBPLAD_02252	9.03e-16	-	-	-	-	-	-	-	-
HEGBPLAD_02253	8.03e-92	-	-	-	-	-	-	-	-
HEGBPLAD_02255	1.78e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HEGBPLAD_02256	4.6e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
HEGBPLAD_02257	7.76e-100	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HEGBPLAD_02258	5.52e-241	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HEGBPLAD_02259	2.05e-153	-	-	-	I	-	-	-	phosphatase
HEGBPLAD_02260	3.88e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HEGBPLAD_02261	3.03e-129	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HEGBPLAD_02262	1.4e-117	-	-	-	K	-	-	-	Transcriptional regulator
HEGBPLAD_02263	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HEGBPLAD_02264	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HEGBPLAD_02265	1.29e-153	dacB	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HEGBPLAD_02266	1.11e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HEGBPLAD_02267	1.62e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HEGBPLAD_02268	1.42e-08	-	-	-	-	-	-	-	-
HEGBPLAD_02269	0.0	-	-	-	M	-	-	-	MucBP domain
HEGBPLAD_02270	4.66e-117	XK27_09665	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
HEGBPLAD_02272	1.75e-108	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HEGBPLAD_02273	2.26e-96	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HEGBPLAD_02274	1.33e-126	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HEGBPLAD_02275	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HEGBPLAD_02276	7.52e-196	-	-	-	S	-	-	-	PglZ domain
HEGBPLAD_02277	0.0	-	4.1.1.98	-	H	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HEGBPLAD_02278	4.05e-237	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HEGBPLAD_02279	1.42e-57	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HEGBPLAD_02280	5.98e-211	-	-	-	K	-	-	-	LysR substrate binding domain
HEGBPLAD_02281	1.38e-131	-	-	-	-	-	-	-	-
HEGBPLAD_02282	3.7e-30	-	-	-	-	-	-	-	-
HEGBPLAD_02283	2.09e-244	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEGBPLAD_02284	1.59e-243	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HEGBPLAD_02285	3.46e-95	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HEGBPLAD_02286	9.03e-108	-	-	-	-	-	-	-	-
HEGBPLAD_02287	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HEGBPLAD_02288	6.36e-134	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HEGBPLAD_02289	5.07e-53	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HEGBPLAD_02290	6.69e-97	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HEGBPLAD_02291	5.88e-279	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HEGBPLAD_02292	4.13e-116	pts21A	-	-	G	ko:K02755	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HEGBPLAD_02293	2e-52	-	-	-	S	-	-	-	Cytochrome B5
HEGBPLAD_02294	0.0	-	-	-	-	-	-	-	-
HEGBPLAD_02295	5.62e-165	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HEGBPLAD_02296	9.31e-15	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HEGBPLAD_02297	5.53e-153	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HEGBPLAD_02298	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HEGBPLAD_02299	6.88e-296	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HEGBPLAD_02300	3.21e-123	-	-	-	P	-	-	-	Cadmium resistance transporter
HEGBPLAD_02301	1.73e-64	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HEGBPLAD_02302	2.46e-148	-	-	-	S	-	-	-	SNARE associated Golgi protein
HEGBPLAD_02303	1.17e-60	-	-	-	-	-	-	-	-
HEGBPLAD_02304	1.18e-94	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
HEGBPLAD_02305	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HEGBPLAD_02306	7.73e-155	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEGBPLAD_02307	2.88e-106	gtcA3	-	-	S	-	-	-	GtrA-like protein
HEGBPLAD_02308	2.93e-169	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
HEGBPLAD_02309	1.15e-43	-	-	-	-	-	-	-	-
HEGBPLAD_02311	4.57e-45	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HEGBPLAD_02312	4.31e-214	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HEGBPLAD_02313	3.73e-190	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HEGBPLAD_02314	1.95e-189	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HEGBPLAD_02315	6.52e-270	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
HEGBPLAD_02316	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HEGBPLAD_02317	3.52e-57	-	-	-	S	-	-	-	Cupredoxin-like domain
HEGBPLAD_02318	1.93e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
HEGBPLAD_02319	0.0	aapA	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HEGBPLAD_02320	4.26e-89	aapA	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HEGBPLAD_02321	1.77e-110	aapA	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HEGBPLAD_02322	1.33e-179	-	-	-	K	-	-	-	Helix-turn-helix domain
HEGBPLAD_02323	3.05e-289	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HEGBPLAD_02324	6.69e-61	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEGBPLAD_02325	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HEGBPLAD_02326	4.84e-230	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HEGBPLAD_02327	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HEGBPLAD_02328	5.5e-209	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HEGBPLAD_02329	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HEGBPLAD_02330	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HEGBPLAD_02331	3.28e-163	mleR	-	-	K	-	-	-	LysR substrate binding domain
HEGBPLAD_02332	4.03e-35	mleR	-	-	K	-	-	-	LysR substrate binding domain
HEGBPLAD_02333	4.58e-80	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HEGBPLAD_02335	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
HEGBPLAD_02336	1.51e-85	-	-	-	KOT	ko:K07813	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01002	May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
HEGBPLAD_02337	9.62e-19	-	-	-	-	-	-	-	-
HEGBPLAD_02338	4.39e-211	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HEGBPLAD_02339	3.67e-174	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HEGBPLAD_02340	1.32e-101	nrp	-	-	K	ko:K16509	-	ko00000	ArsC family
HEGBPLAD_02341	0.0	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
HEGBPLAD_02342	1.96e-21	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
HEGBPLAD_02343	1.76e-15	-	-	-	-	-	-	-	-
HEGBPLAD_02344	2.1e-116	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HEGBPLAD_02345	2.43e-91	-	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
HEGBPLAD_02346	1.92e-169	-	-	-	-	-	-	-	-
HEGBPLAD_02347	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HEGBPLAD_02348	1.18e-175	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HEGBPLAD_02349	7.3e-60	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HEGBPLAD_02350	1.16e-208	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
HEGBPLAD_02351	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HEGBPLAD_02352	1.3e-282	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEGBPLAD_02353	6.35e-230	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HEGBPLAD_02354	1.21e-268	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HEGBPLAD_02355	3.95e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HEGBPLAD_02356	3.73e-110	-	-	-	-	-	-	-	-
HEGBPLAD_02357	4.86e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HEGBPLAD_02358	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEGBPLAD_02359	8.47e-241	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HEGBPLAD_02360	2.16e-39	-	-	-	-	-	-	-	-
HEGBPLAD_02361	6.78e-160	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HEGBPLAD_02362	3.09e-219	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HEGBPLAD_02363	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HEGBPLAD_02364	1.02e-155	-	-	-	S	-	-	-	repeat protein
HEGBPLAD_02365	1.39e-156	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HEGBPLAD_02366	0.0	-	-	-	N	-	-	-	domain, Protein
HEGBPLAD_02367	1.73e-248	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HEGBPLAD_02368	1.19e-152	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
HEGBPLAD_02369	4.64e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HEGBPLAD_02370	9.49e-308	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HEGBPLAD_02371	3.19e-285	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HEGBPLAD_02372	4.94e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HEGBPLAD_02373	6.11e-277	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HEGBPLAD_02374	5.85e-158	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HEGBPLAD_02375	1.83e-45	-	-	-	-	-	-	-	-
HEGBPLAD_02376	3.51e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HEGBPLAD_02377	3.46e-242	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HEGBPLAD_02378	2.05e-20	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HEGBPLAD_02379	5.18e-47	-	-	-	K	-	-	-	LytTr DNA-binding domain
HEGBPLAD_02380	1.47e-100	-	-	-	U	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
HEGBPLAD_02381	3.64e-101	cylA	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
HEGBPLAD_02382	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HEGBPLAD_02383	7.59e-123	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HEGBPLAD_02384	2.4e-186	ylmH	-	-	S	-	-	-	S4 domain protein
HEGBPLAD_02385	6.45e-49	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HEGBPLAD_02386	1.56e-93	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HEGBPLAD_02387	1.89e-294	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HEGBPLAD_02388	3.55e-312	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HEGBPLAD_02389	2.34e-208	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HEGBPLAD_02390	1.43e-252	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HEGBPLAD_02391	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HEGBPLAD_02392	2.81e-231	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HEGBPLAD_02393	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HEGBPLAD_02394	7.01e-76	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HEGBPLAD_02395	1.22e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HEGBPLAD_02396	3.28e-100	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HEGBPLAD_02397	1.31e-81	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
HEGBPLAD_02398	1.43e-223	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HEGBPLAD_02399	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HEGBPLAD_02400	1.65e-123	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HEGBPLAD_02401	9.75e-145	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HEGBPLAD_02402	2.95e-300	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HEGBPLAD_02404	1.12e-207	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HEGBPLAD_02405	6.85e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEGBPLAD_02406	1.29e-261	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
HEGBPLAD_02407	1.28e-73	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HEGBPLAD_02408	1.6e-246	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HEGBPLAD_02409	1.7e-148	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HEGBPLAD_02410	4.44e-222	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HEGBPLAD_02411	1.06e-192	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HEGBPLAD_02412	9.08e-157	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HEGBPLAD_02413	2.24e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
HEGBPLAD_02414	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HEGBPLAD_02415	1e-106	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HEGBPLAD_02416	3.04e-135	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HEGBPLAD_02417	7.12e-170	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HEGBPLAD_02418	5.37e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HEGBPLAD_02419	2.81e-178	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HEGBPLAD_02420	8.88e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HEGBPLAD_02440	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HEGBPLAD_02441	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HEGBPLAD_02442	9.36e-71	-	-	-	-	-	-	-	-
HEGBPLAD_02443	3.07e-96	-	-	-	-	-	-	-	-
HEGBPLAD_02444	5.58e-195	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HEGBPLAD_02445	5.35e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HEGBPLAD_02446	7.41e-163	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HEGBPLAD_02447	3.51e-272	-	-	-	J	-	-	-	translation release factor activity
HEGBPLAD_02448	1.91e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HEGBPLAD_02449	6.26e-306	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HEGBPLAD_02450	6.96e-301	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEGBPLAD_02451	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HEGBPLAD_02452	1.86e-180	-	-	-	S	-	-	-	zinc-ribbon domain
HEGBPLAD_02454	4.29e-50	-	-	-	-	-	-	-	-
HEGBPLAD_02455	1.22e-170	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HEGBPLAD_02456	2.35e-231	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HEGBPLAD_02457	0.0	-	-	-	I	-	-	-	acetylesterase activity
HEGBPLAD_02458	1e-236	-	-	-	M	-	-	-	Collagen binding domain
HEGBPLAD_02459	3.44e-40	-	-	-	M	-	-	-	Collagen binding domain
HEGBPLAD_02460	5.45e-203	yicL	-	-	EG	-	-	-	EamA-like transporter family
HEGBPLAD_02461	3.03e-166	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HEGBPLAD_02462	8.13e-81	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
HEGBPLAD_02463	7.47e-133	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HEGBPLAD_02464	7.43e-130	padR	-	-	K	-	-	-	Virulence activator alpha C-term
HEGBPLAD_02465	2.51e-103	-	-	-	T	-	-	-	Universal stress protein family
HEGBPLAD_02466	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HEGBPLAD_02467	4.04e-241	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HEGBPLAD_02468	6.42e-209	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEGBPLAD_02469	4.99e-88	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HEGBPLAD_02470	2.96e-208	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
HEGBPLAD_02471	1.82e-184	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
HEGBPLAD_02472	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HEGBPLAD_02473	3.41e-59	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HEGBPLAD_02474	9.24e-140	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HEGBPLAD_02475	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HEGBPLAD_02476	1.56e-275	-	-	-	T	-	-	-	diguanylate cyclase
HEGBPLAD_02477	2.25e-45	-	-	-	-	-	-	-	-
HEGBPLAD_02478	3.8e-47	-	-	-	-	-	-	-	-
HEGBPLAD_02479	1.4e-105	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
HEGBPLAD_02480	3.94e-219	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
HEGBPLAD_02481	2.34e-206	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HEGBPLAD_02483	2.68e-32	-	-	-	-	-	-	-	-
HEGBPLAD_02484	2.31e-177	-	-	-	F	-	-	-	NUDIX domain
HEGBPLAD_02485	4.32e-21	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
HEGBPLAD_02486	5.04e-229	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
HEGBPLAD_02487	1.31e-64	-	-	-	-	-	-	-	-
HEGBPLAD_02488	6.24e-120	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HEGBPLAD_02489	2.1e-218	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HEGBPLAD_02490	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HEGBPLAD_02491	8.39e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HEGBPLAD_02492	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HEGBPLAD_02493	1.06e-53	-	-	-	-	-	-	-	-
HEGBPLAD_02494	4e-40	-	-	-	S	-	-	-	CsbD-like
HEGBPLAD_02495	4.48e-55	-	-	-	S	-	-	-	transglycosylase associated protein
HEGBPLAD_02496	5.79e-21	-	-	-	-	-	-	-	-
HEGBPLAD_02497	2.51e-47	-	-	-	-	-	-	-	-
HEGBPLAD_02498	1.21e-209	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HEGBPLAD_02499	3.23e-86	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HEGBPLAD_02500	5.28e-100	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HEGBPLAD_02501	6.05e-108	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
HEGBPLAD_02502	2.05e-55	-	-	-	-	-	-	-	-
HEGBPLAD_02503	1.45e-60	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HEGBPLAD_02504	2.33e-131	-	1.14.99.53	AA10	S	ko:K21713	-	ko00000,ko01000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
HEGBPLAD_02505	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HEGBPLAD_02506	1.88e-178	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEGBPLAD_02507	6.03e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HEGBPLAD_02508	1.32e-224	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HEGBPLAD_02509	8.88e-213	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HEGBPLAD_02510	1.32e-310	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HEGBPLAD_02511	5.02e-294	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HEGBPLAD_02512	3.45e-209	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HEGBPLAD_02513	1.07e-156	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HEGBPLAD_02514	4.29e-101	-	-	-	-	-	-	-	-
HEGBPLAD_02515	5.09e-51	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HEGBPLAD_02516	1.28e-84	-	-	-	FG	-	-	-	HIT domain
HEGBPLAD_02517	8.27e-221	ydhF	-	-	S	-	-	-	Aldo keto reductase
HEGBPLAD_02518	9.04e-48	-	-	-	S	-	-	-	Pfam:DUF59
HEGBPLAD_02519	1.12e-206	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HEGBPLAD_02520	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HEGBPLAD_02521	1.87e-249	-	-	-	V	-	-	-	Beta-lactamase
HEGBPLAD_02522	1.52e-124	-	-	-	V	-	-	-	VanZ like family
HEGBPLAD_02523	2.68e-198	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HEGBPLAD_02524	8.51e-246	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
HEGBPLAD_02525	0.0	ydaO	-	-	E	-	-	-	amino acid
HEGBPLAD_02526	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HEGBPLAD_02527	9.82e-55	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HEGBPLAD_02528	2.38e-140	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HEGBPLAD_02529	3.67e-154	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HEGBPLAD_02530	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HEGBPLAD_02531	1.53e-36	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HEGBPLAD_02532	8.96e-35	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HEGBPLAD_02533	1.81e-55	pts36A	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HEGBPLAD_02534	2.17e-218	-	-	-	GKT	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HEGBPLAD_02535	8.74e-50	-	-	-	GM	-	-	-	NAD(P)H-binding
HEGBPLAD_02536	9.71e-47	-	-	-	-	-	-	-	-
HEGBPLAD_02537	1.9e-144	-	-	-	Q	-	-	-	Methyltransferase domain
HEGBPLAD_02538	5.06e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HEGBPLAD_02539	9.26e-233	ydbI	-	-	K	-	-	-	AI-2E family transporter
HEGBPLAD_02540	9.28e-271	xylR	-	-	GK	-	-	-	ROK family
HEGBPLAD_02541	3.91e-124	tag2	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HEGBPLAD_02542	1.13e-270	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
HEGBPLAD_02543	1.69e-127	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HEGBPLAD_02544	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HEGBPLAD_02545	1.8e-134	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HEGBPLAD_02546	1.59e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HEGBPLAD_02547	9.61e-84	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HEGBPLAD_02548	1.22e-108	cvpA	-	-	S	-	-	-	Colicin V production protein
HEGBPLAD_02549	6.54e-215	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HEGBPLAD_02550	4.21e-35	-	-	-	EGP	-	-	-	Major Facilitator
HEGBPLAD_02551	3.51e-149	-	-	-	EGP	-	-	-	Major Facilitator
HEGBPLAD_02552	1.15e-84	-	-	-	EGP	-	-	-	Major Facilitator
HEGBPLAD_02554	1.07e-52	-	-	-	-	-	-	-	-
HEGBPLAD_02555	0.0	-	-	-	G	-	-	-	Major Facilitator
HEGBPLAD_02556	3.01e-274	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HEGBPLAD_02557	4.5e-119	-	-	-	-	-	-	-	-
HEGBPLAD_02558	1.84e-299	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HEGBPLAD_02559	2e-244	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HEGBPLAD_02560	2.93e-114	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HEGBPLAD_02561	5.17e-220	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HEGBPLAD_02562	1.46e-239	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HEGBPLAD_02563	2.06e-170	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HEGBPLAD_02564	5.15e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HEGBPLAD_02565	1.72e-115	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HEGBPLAD_02566	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HEGBPLAD_02567	2.54e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HEGBPLAD_02568	4.21e-266	pbpX2	-	-	V	-	-	-	Beta-lactamase
HEGBPLAD_02569	8.59e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HEGBPLAD_02570	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEGBPLAD_02571	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HEGBPLAD_02572	6.73e-46	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEGBPLAD_02573	1.68e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HEGBPLAD_02574	2.84e-36	-	-	-	-	-	-	-	-
HEGBPLAD_02575	6.46e-51	-	-	-	L	ko:K07484	-	ko00000	IS66 Orf2 like protein
HEGBPLAD_02576	2.75e-282	-	-	-	L	-	-	-	Transposase IS66 family
HEGBPLAD_02577	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HEGBPLAD_02578	5.59e-64	-	-	-	-	-	-	-	-
HEGBPLAD_02579	4.78e-65	-	-	-	-	-	-	-	-
HEGBPLAD_02580	4.34e-145	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HEGBPLAD_02581	8.31e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HEGBPLAD_02582	2.57e-171	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HEGBPLAD_02583	1.49e-75	-	-	-	-	-	-	-	-
HEGBPLAD_02584	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HEGBPLAD_02585	8.2e-102	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HEGBPLAD_02586	9.14e-146	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
HEGBPLAD_02587	7.3e-211	-	-	-	G	-	-	-	Fructosamine kinase
HEGBPLAD_02588	1.91e-198	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
HEGBPLAD_02589	2.47e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HEGBPLAD_02590	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HEGBPLAD_02591	2.07e-129	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HEGBPLAD_02592	1.25e-203	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HEGBPLAD_02593	8.73e-283	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HEGBPLAD_02594	1.42e-215	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HEGBPLAD_02595	1.17e-162	-	-	-	C	-	-	-	Enoyl-(Acyl carrier protein) reductase
HEGBPLAD_02596	2.32e-194	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HEGBPLAD_02597	1.09e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HEGBPLAD_02598	9.21e-94	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HEGBPLAD_02599	1.38e-228	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HEGBPLAD_02600	3.14e-109	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HEGBPLAD_02601	1.15e-94	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HEGBPLAD_02602	7.92e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HEGBPLAD_02603	1.92e-187	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HEGBPLAD_02604	8.64e-224	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HEGBPLAD_02605	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HEGBPLAD_02606	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HEGBPLAD_02607	1.74e-251	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HEGBPLAD_02608	6.86e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HEGBPLAD_02609	8.54e-214	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEGBPLAD_02610	1.68e-252	-	-	-	-	-	-	-	-
HEGBPLAD_02611	6.84e-87	-	-	-	-	-	-	-	-
HEGBPLAD_02612	5.47e-132	-	-	-	-	-	-	-	-
HEGBPLAD_02613	1.66e-167	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HEGBPLAD_02614	1.23e-151	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEGBPLAD_02615	8.61e-147	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HEGBPLAD_02616	2.4e-102	-	-	-	K	-	-	-	MarR family
HEGBPLAD_02617	2.71e-108	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HEGBPLAD_02619	3.43e-203	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HEGBPLAD_02620	4.08e-171	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HEGBPLAD_02621	4.31e-258	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEGBPLAD_02622	5.27e-133	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
HEGBPLAD_02623	0.0	nox4	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HEGBPLAD_02625	5.37e-221	cryZ	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HEGBPLAD_02626	6.68e-206	-	-	-	K	-	-	-	Transcriptional regulator
HEGBPLAD_02627	2.89e-100	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
HEGBPLAD_02628	1.69e-144	-	-	-	GM	-	-	-	NmrA-like family
HEGBPLAD_02629	3.07e-205	-	-	-	S	-	-	-	Alpha beta hydrolase
HEGBPLAD_02630	1.75e-167	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HEGBPLAD_02631	3.41e-89	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HEGBPLAD_02632	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
HEGBPLAD_02633	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HEGBPLAD_02634	1.22e-157	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HEGBPLAD_02635	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HEGBPLAD_02636	3.47e-286	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HEGBPLAD_02638	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
HEGBPLAD_02639	7.12e-62	-	-	-	-	-	-	-	-
HEGBPLAD_02640	1.78e-118	-	-	-	-	-	-	-	-
HEGBPLAD_02641	2.2e-111	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HEGBPLAD_02642	6.12e-146	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HEGBPLAD_02643	4.56e-78	-	-	-	-	-	-	-	-
HEGBPLAD_02644	5.37e-74	-	-	-	-	-	-	-	-
HEGBPLAD_02645	3.14e-179	agrA	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HEGBPLAD_02646	1.7e-282	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HEGBPLAD_02647	5.89e-108	-	-	-	K	-	-	-	Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HEGBPLAD_02648	3.12e-292	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HEGBPLAD_02649	3.08e-123	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HEGBPLAD_02650	5.34e-72	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HEGBPLAD_02651	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
HEGBPLAD_02652	8.36e-154	rpiA2	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HEGBPLAD_02653	2.88e-130	zmp1	-	-	O	-	-	-	Zinc-dependent metalloprotease
HEGBPLAD_02654	8.95e-60	-	-	-	-	-	-	-	-
HEGBPLAD_02655	1.28e-223	hicD1	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HEGBPLAD_02656	4.26e-308	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HEGBPLAD_02657	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HEGBPLAD_02658	5.06e-280	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HEGBPLAD_02659	5.47e-159	-	-	-	S	-	-	-	YjbR
HEGBPLAD_02661	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HEGBPLAD_02662	0.0	-	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
HEGBPLAD_02663	2.26e-99	pts23A	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HEGBPLAD_02664	5.9e-193	-	-	-	K	-	-	-	Helix-turn-helix domain
HEGBPLAD_02665	2.86e-72	-	-	-	-	-	-	-	-
HEGBPLAD_02666	9.17e-204	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HEGBPLAD_02667	2.03e-84	-	-	-	-	-	-	-	-
HEGBPLAD_02668	0.0	-	-	-	P	-	-	-	Concanavalin A-like lectin/glucanases superfamily
HEGBPLAD_02669	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEGBPLAD_02670	9.42e-258	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HEGBPLAD_02671	3.31e-198	tagG	-	-	U	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HEGBPLAD_02672	1.83e-279	-	-	-	-	-	-	-	-
HEGBPLAD_02673	4.46e-284	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HEGBPLAD_02674	7.29e-80	-	-	-	S	-	-	-	CHY zinc finger
HEGBPLAD_02675	1.18e-224	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HEGBPLAD_02676	1.54e-123	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HEGBPLAD_02677	6.4e-54	-	-	-	-	-	-	-	-
HEGBPLAD_02678	2.88e-194	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HEGBPLAD_02679	2.2e-145	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HEGBPLAD_02680	4.01e-118	-	-	-	EG	-	-	-	EamA-like transporter family
HEGBPLAD_02681	7.23e-107	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HEGBPLAD_02682	3.43e-148	-	-	-	GM	-	-	-	NmrA-like family
HEGBPLAD_02683	4.79e-21	-	-	-	-	-	-	-	-
HEGBPLAD_02684	4.59e-74	-	-	-	-	-	-	-	-
HEGBPLAD_02685	1.87e-102	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HEGBPLAD_02686	1.11e-111	-	-	-	-	-	-	-	-
HEGBPLAD_02687	2.11e-82	-	-	-	-	-	-	-	-
HEGBPLAD_02688	4.98e-275	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
HEGBPLAD_02689	1.7e-70	-	-	-	-	-	-	-	-
HEGBPLAD_02690	5.74e-86	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HEGBPLAD_02691	9.97e-94	spxA	-	-	P	ko:K16509	-	ko00000	ArsC family
HEGBPLAD_02692	8.7e-86	-	-	-	K	ko:K22296	-	ko00000,ko03000	Winged helix DNA-binding domain
HEGBPLAD_02693	1.31e-207	-	-	-	GM	-	-	-	NmrA-like family
HEGBPLAD_02694	1.11e-289	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HEGBPLAD_02695	1.99e-95	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
HEGBPLAD_02696	4.26e-54	-	-	-	-	-	-	-	-
HEGBPLAD_02697	4.83e-98	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HEGBPLAD_02698	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HEGBPLAD_02699	4.38e-243	pva2	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HEGBPLAD_02700	9.94e-143	-	-	-	S	-	-	-	VIT family
HEGBPLAD_02701	1.8e-153	-	-	-	S	-	-	-	membrane
HEGBPLAD_02702	8.98e-70	-	-	-	EG	-	-	-	EamA-like transporter family
HEGBPLAD_02705	2.01e-81	-	-	-	-	-	-	-	-
HEGBPLAD_02706	6.18e-71	-	-	-	-	-	-	-	-
HEGBPLAD_02707	2.89e-107	-	-	-	M	-	-	-	PFAM NLP P60 protein
HEGBPLAD_02708	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
HEGBPLAD_02709	4.45e-38	-	-	-	-	-	-	-	-
HEGBPLAD_02710	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HEGBPLAD_02711	1.55e-149	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HEGBPLAD_02712	5.33e-114	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HEGBPLAD_02713	1.47e-14	-	-	-	S	-	-	-	Bacteriophage holin
HEGBPLAD_02714	3.08e-78	-	-	-	V	-	-	-	Abi-like protein
HEGBPLAD_02715	1.4e-180	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
HEGBPLAD_02716	7.39e-85	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HEGBPLAD_02717	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HEGBPLAD_02718	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HEGBPLAD_02719	6.55e-183	-	-	-	-	-	-	-	-
HEGBPLAD_02720	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HEGBPLAD_02721	2.37e-270	yttB	-	-	EGP	-	-	-	Major Facilitator
HEGBPLAD_02722	3.45e-83	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HEGBPLAD_02723	1.12e-173	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HEGBPLAD_02724	4.71e-74	-	-	-	S	-	-	-	SdpI/YhfL protein family
HEGBPLAD_02725	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HEGBPLAD_02726	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	Bacterial regulatory proteins, gntR family
HEGBPLAD_02727	1.02e-277	araT2	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HEGBPLAD_02728	1.84e-204	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HEGBPLAD_02729	3.59e-26	-	-	-	-	-	-	-	-
HEGBPLAD_02730	2.09e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HEGBPLAD_02731	5.26e-204	mleR	-	-	K	-	-	-	LysR family
HEGBPLAD_02732	1.29e-148	-	-	-	GM	-	-	-	NAD(P)H-binding
HEGBPLAD_02733	1.24e-120	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HEGBPLAD_02734	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HEGBPLAD_02735	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HEGBPLAD_02736	4.35e-214	oroP	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
HEGBPLAD_02737	9.05e-144	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HEGBPLAD_02738	2.57e-160	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HEGBPLAD_02739	5.54e-214	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HEGBPLAD_02740	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HEGBPLAD_02741	3.36e-272	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HEGBPLAD_02742	5.6e-309	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HEGBPLAD_02743	1.22e-220	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HEGBPLAD_02744	7.13e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HEGBPLAD_02745	0.0	pucR_2	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
HEGBPLAD_02746	5.14e-304	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HEGBPLAD_02747	5.67e-280	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
HEGBPLAD_02748	4.51e-206	-	-	-	GM	-	-	-	NmrA-like family
HEGBPLAD_02749	5.09e-199	-	-	-	T	-	-	-	EAL domain
HEGBPLAD_02750	1.77e-119	-	-	-	-	-	-	-	-
HEGBPLAD_02751	4.94e-181	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HEGBPLAD_02752	1.95e-93	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HEGBPLAD_02753	3.85e-159	-	-	-	E	-	-	-	Methionine synthase
HEGBPLAD_02754	1.5e-277	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HEGBPLAD_02755	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HEGBPLAD_02756	6.25e-132	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HEGBPLAD_02757	2.97e-243	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HEGBPLAD_02758	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HEGBPLAD_02759	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEGBPLAD_02760	6.91e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEGBPLAD_02761	1.17e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEGBPLAD_02762	3.39e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HEGBPLAD_02763	2.75e-268	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HEGBPLAD_02764	1.08e-103	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HEGBPLAD_02765	1.31e-303	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HEGBPLAD_02766	9.92e-143	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HEGBPLAD_02767	7.16e-178	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
HEGBPLAD_02768	2.04e-189	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HEGBPLAD_02769	1.15e-150	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
HEGBPLAD_02770	4.15e-191	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HEGBPLAD_02771	1.44e-230	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HEGBPLAD_02772	1.38e-176	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEGBPLAD_02773	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HEGBPLAD_02774	5.36e-53	-	-	-	-	-	-	-	-
HEGBPLAD_02775	8.2e-81	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HEGBPLAD_02776	7.89e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEGBPLAD_02777	1.89e-187	-	-	-	-	-	-	-	-
HEGBPLAD_02778	3.15e-103	usp5	-	-	T	-	-	-	universal stress protein
HEGBPLAD_02779	4.02e-95	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HEGBPLAD_02780	1.76e-114	-	-	-	-	-	-	-	-
HEGBPLAD_02781	4.17e-67	-	-	-	-	-	-	-	-
HEGBPLAD_02782	4.79e-13	-	-	-	-	-	-	-	-
HEGBPLAD_02783	1.32e-293	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HEGBPLAD_02784	1.16e-110	-	-	-	F	-	-	-	belongs to the nudix hydrolase family
HEGBPLAD_02785	6.17e-151	-	-	-	-	-	-	-	-
HEGBPLAD_02786	1.21e-69	-	-	-	-	-	-	-	-
HEGBPLAD_02788	1.62e-109	-	-	-	S	-	-	-	Pfam:DUF3816
HEGBPLAD_02789	1.21e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HEGBPLAD_02790	3.63e-143	-	-	-	-	-	-	-	-
HEGBPLAD_02791	6.89e-226	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HEGBPLAD_02793	1.57e-184	-	-	-	S	-	-	-	Peptidase_C39 like family
HEGBPLAD_02794	8.53e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HEGBPLAD_02795	3.38e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HEGBPLAD_02796	5.24e-66	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
HEGBPLAD_02798	9.88e-26	-	-	-	-	-	-	-	-
HEGBPLAD_02800	5.23e-119	-	-	-	S	-	-	-	Bacteriophage Mu Gam like protein
HEGBPLAD_02801	4.76e-126	-	-	-	S	-	-	-	AAA domain
HEGBPLAD_02802	4.48e-240	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HEGBPLAD_02804	8.98e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
HEGBPLAD_02805	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
HEGBPLAD_02807	2.49e-63	-	-	-	-	-	-	-	-
HEGBPLAD_02808	7.54e-188	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
HEGBPLAD_02810	1.39e-99	-	-	-	-	-	-	-	-
HEGBPLAD_02811	6.11e-48	-	-	-	-	-	-	-	-
HEGBPLAD_02812	7.52e-80	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HEGBPLAD_02813	1.46e-122	-	-	-	-	-	-	-	-
HEGBPLAD_02814	4.84e-160	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HEGBPLAD_02815	1.04e-124	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HEGBPLAD_02816	2.1e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HEGBPLAD_02817	1.28e-45	-	-	-	-	-	-	-	-
HEGBPLAD_02818	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HEGBPLAD_02819	1.63e-281	pbpX	-	-	V	-	-	-	Beta-lactamase
HEGBPLAD_02820	3.74e-264	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HEGBPLAD_02821	1.23e-200	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HEGBPLAD_02822	3.27e-168	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HEGBPLAD_02823	1.37e-117	tnp2	-	-	L	ko:K07485	-	ko00000	Transposase
HEGBPLAD_02824	4.78e-307	-	-	-	M	-	-	-	domain protein
HEGBPLAD_02825	5.81e-96	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HEGBPLAD_02826	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HEGBPLAD_02827	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HEGBPLAD_02829	5.42e-206	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HEGBPLAD_02830	2.84e-75	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HEGBPLAD_02831	2.42e-54	-	-	-	K	-	-	-	prlF antitoxin for toxin YhaV_toxin
HEGBPLAD_02832	3.92e-141	-	-	-	L	-	-	-	Integrase
HEGBPLAD_02833	5.77e-149	-	-	-	-	-	-	-	-
HEGBPLAD_02834	1.67e-240	-	-	-	S	-	-	-	MobA/MobL family
HEGBPLAD_02838	6.86e-177	-	-	-	-	-	-	-	-
HEGBPLAD_02839	0.0	acdH	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
HEGBPLAD_02840	8.16e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HEGBPLAD_02842	6.77e-305	xylP1	-	-	G	-	-	-	MFS/sugar transport protein
HEGBPLAD_02843	4.09e-170	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HEGBPLAD_02844	7.28e-42	-	-	-	-	-	-	-	-
HEGBPLAD_02846	3.03e-25	-	-	-	M	ko:K14193	ko05150,map05150	ko00000,ko00001	Iron Transport-associated domain
HEGBPLAD_02847	1.72e-64	isdE	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HEGBPLAD_02848	2.96e-64	isdF	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	FecCD transport family
HEGBPLAD_02849	1.37e-34	fepC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HEGBPLAD_02850	9.26e-170	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HEGBPLAD_02851	2.94e-155	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HEGBPLAD_02852	1.36e-77	-	-	-	-	-	-	-	-
HEGBPLAD_02853	7.79e-112	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HEGBPLAD_02854	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HEGBPLAD_02855	5e-147	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HEGBPLAD_02856	2.4e-169	-	-	-	-	-	-	-	-
HEGBPLAD_02857	7.44e-186	-	-	-	D	-	-	-	AAA domain
HEGBPLAD_02858	4.16e-46	-	-	-	-	-	-	-	-
HEGBPLAD_02859	1.36e-50	-	-	-	-	-	-	-	-
HEGBPLAD_02860	2.27e-247	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HEGBPLAD_02861	5.83e-117	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
HEGBPLAD_02862	1.03e-34	-	-	-	-	-	-	-	-
HEGBPLAD_02863	1.28e-184	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HEGBPLAD_02864	2.88e-164	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
HEGBPLAD_02865	9.76e-83	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
HEGBPLAD_02866	1.14e-134	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HEGBPLAD_02867	6.52e-216	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HEGBPLAD_02868	3.74e-48	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
HEGBPLAD_02869	4.31e-76	-	-	-	S	-	-	-	Enterocin A Immunity
HEGBPLAD_02870	1.55e-114	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HEGBPLAD_02871	8.76e-133	-	-	-	-	-	-	-	-
HEGBPLAD_02872	2.22e-299	-	-	-	S	-	-	-	module of peptide synthetase
HEGBPLAD_02873	8.66e-130	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HEGBPLAD_02875	5.93e-163	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
HEGBPLAD_02876	0.0	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEGBPLAD_02877	3.85e-81	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEGBPLAD_02878	8.79e-199	-	-	-	GM	-	-	-	NmrA-like family
HEGBPLAD_02879	2.54e-101	-	-	-	K	-	-	-	MerR family regulatory protein
HEGBPLAD_02880	3.54e-190	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HEGBPLAD_02881	1.01e-189	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
HEGBPLAD_02882	6.26e-101	-	-	-	-	-	-	-	-
HEGBPLAD_02883	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEGBPLAD_02884	1.76e-152	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEGBPLAD_02885	2.44e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HEGBPLAD_02886	2.93e-260	-	-	-	S	-	-	-	DUF218 domain
HEGBPLAD_02887	1.83e-233	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HEGBPLAD_02888	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HEGBPLAD_02889	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEGBPLAD_02890	1.18e-202	-	-	-	S	-	-	-	Putative adhesin
HEGBPLAD_02891	1.73e-132	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HEGBPLAD_02892	1.72e-69	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
HEGBPLAD_02893	1.46e-125	-	-	-	KT	-	-	-	response to antibiotic
HEGBPLAD_02894	2.53e-161	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HEGBPLAD_02895	3.02e-176	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HEGBPLAD_02896	2.11e-158	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HEGBPLAD_02897	4.5e-169	fliY	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HEGBPLAD_02898	2.31e-299	-	-	-	EK	-	-	-	Aminotransferase, class I
HEGBPLAD_02899	1.37e-215	-	-	-	K	-	-	-	LysR substrate binding domain
HEGBPLAD_02900	3e-186	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HEGBPLAD_02901	3.45e-198	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HEGBPLAD_02902	1.66e-288	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
HEGBPLAD_02903	4.27e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HEGBPLAD_02904	2.12e-191	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HEGBPLAD_02905	1.43e-175	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HEGBPLAD_02906	1.02e-200	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HEGBPLAD_02907	1.4e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HEGBPLAD_02908	6.6e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HEGBPLAD_02909	3.49e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HEGBPLAD_02910	3.49e-270	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HEGBPLAD_02911	5.99e-179	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HEGBPLAD_02912	3.27e-159	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HEGBPLAD_02913	1.14e-159	vanR	-	-	K	-	-	-	response regulator
HEGBPLAD_02914	5.61e-273	hpk31	-	-	T	-	-	-	Histidine kinase
HEGBPLAD_02915	2.18e-304	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HEGBPLAD_02916	9.62e-116	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HEGBPLAD_02917	2.05e-167	-	-	-	E	-	-	-	branched-chain amino acid
HEGBPLAD_02918	5.93e-73	-	-	-	S	-	-	-	branched-chain amino acid
HEGBPLAD_02919	3.93e-140	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HEGBPLAD_02921	2.9e-70	-	-	-	-	-	-	-	-
HEGBPLAD_02922	5.61e-98	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HEGBPLAD_02923	2.89e-124	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HEGBPLAD_02924	1.59e-257	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
HEGBPLAD_02925	1.24e-205	-	-	-	-	-	-	-	-
HEGBPLAD_02926	4.09e-292	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HEGBPLAD_02927	1.37e-141	-	-	-	-	-	-	-	-