ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HEKLMFOH_00002 6.75e-314 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HEKLMFOH_00003 9.84e-192 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 YmdB-like protein
HEKLMFOH_00004 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HEKLMFOH_00005 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HEKLMFOH_00006 1.58e-139 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HEKLMFOH_00007 4.74e-243 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HEKLMFOH_00008 9.73e-255 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HEKLMFOH_00009 3.74e-289 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HEKLMFOH_00010 9.44e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HEKLMFOH_00011 2.24e-230 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEKLMFOH_00012 5.26e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
HEKLMFOH_00013 0.0 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HEKLMFOH_00014 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HEKLMFOH_00015 1.94e-59 yrzL - - S - - - Belongs to the UPF0297 family
HEKLMFOH_00016 7.07e-97 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HEKLMFOH_00017 2.47e-68 yrzB - - S - - - Belongs to the UPF0473 family
HEKLMFOH_00018 1.62e-53 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HEKLMFOH_00019 4.45e-116 cvpA - - S - - - Colicin V production protein
HEKLMFOH_00020 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HEKLMFOH_00021 6.22e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HEKLMFOH_00022 1.77e-120 yslB - - S - - - Protein of unknown function (DUF2507)
HEKLMFOH_00023 3.54e-191 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HEKLMFOH_00024 3.08e-140 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HEKLMFOH_00025 3.07e-129 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
HEKLMFOH_00026 2.88e-111 ykuL - - S - - - (CBS) domain
HEKLMFOH_00028 1.12e-64 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HEKLMFOH_00029 0.0 - - - U - - - Major Facilitator Superfamily
HEKLMFOH_00030 2.7e-199 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
HEKLMFOH_00031 3.9e-82 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HEKLMFOH_00032 1.38e-73 - - - - - - - -
HEKLMFOH_00033 2.45e-270 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HEKLMFOH_00034 1.23e-231 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
HEKLMFOH_00035 3.3e-175 - - - - - - - -
HEKLMFOH_00036 3.4e-174 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HEKLMFOH_00037 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HEKLMFOH_00038 1.68e-169 yebC - - K - - - Transcriptional regulatory protein
HEKLMFOH_00039 6.51e-221 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
HEKLMFOH_00040 2.6e-218 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
HEKLMFOH_00041 1.61e-64 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
HEKLMFOH_00042 1.16e-106 - - - - - - - -
HEKLMFOH_00044 7.17e-99 - - - - ko:K02248 - ko00000,ko00002,ko02044 -
HEKLMFOH_00045 5.94e-238 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
HEKLMFOH_00046 2.16e-282 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HEKLMFOH_00047 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HEKLMFOH_00048 1.15e-199 yeaE - - S - - - Aldo keto
HEKLMFOH_00049 6.48e-148 - - - S - - - Calcineurin-like phosphoesterase
HEKLMFOH_00050 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HEKLMFOH_00051 2.6e-141 yutD - - S - - - Protein of unknown function (DUF1027)
HEKLMFOH_00052 6.64e-190 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HEKLMFOH_00053 4.37e-154 - - - S - - - Protein of unknown function (DUF1461)
HEKLMFOH_00054 3.37e-119 - - - S - - - WxL domain surface cell wall-binding
HEKLMFOH_00055 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
HEKLMFOH_00056 0.0 - - - M - - - domain protein
HEKLMFOH_00057 0.0 - - - E ko:K03294 - ko00000 Amino Acid
HEKLMFOH_00058 1.75e-185 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
HEKLMFOH_00059 1.19e-157 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
HEKLMFOH_00060 2.63e-115 pgpA 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Phosphatidylglycerophosphatase A
HEKLMFOH_00061 4.07e-144 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HEKLMFOH_00062 4.82e-94 yugI - - J ko:K07570,ko:K07571 - ko00000 general stress protein
HEKLMFOH_00063 3.34e-249 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HEKLMFOH_00064 7.36e-291 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
HEKLMFOH_00065 5.53e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HEKLMFOH_00066 2.34e-151 ymfM - - S ko:K15539 - ko00000 Domain of unknown function (DUF4115)
HEKLMFOH_00067 3.4e-314 ymfH - - S - - - Peptidase M16
HEKLMFOH_00068 9.21e-304 ymfF - - S - - - Peptidase M16 inactive domain protein
HEKLMFOH_00069 1.85e-204 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
HEKLMFOH_00070 8.68e-121 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HEKLMFOH_00071 5.65e-143 - - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
HEKLMFOH_00072 1.57e-190 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
HEKLMFOH_00073 2.04e-150 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HEKLMFOH_00074 3.85e-120 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
HEKLMFOH_00075 1.53e-184 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HEKLMFOH_00076 1.71e-218 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
HEKLMFOH_00077 9.77e-152 radC - - L ko:K03630 - ko00000 DNA repair protein
HEKLMFOH_00078 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HEKLMFOH_00079 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HEKLMFOH_00080 5.75e-119 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HEKLMFOH_00081 1.27e-290 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HEKLMFOH_00082 2.79e-275 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HEKLMFOH_00083 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HEKLMFOH_00084 7.76e-108 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
HEKLMFOH_00085 5.1e-140 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HEKLMFOH_00086 6.78e-81 - - - KLT - - - serine threonine protein kinase
HEKLMFOH_00087 6.01e-147 yktB - - S - - - Belongs to the UPF0637 family
HEKLMFOH_00088 1.3e-104 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
HEKLMFOH_00089 4.23e-306 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
HEKLMFOH_00090 3.68e-55 - - - - - - - -
HEKLMFOH_00091 2.12e-107 uspA - - T - - - universal stress protein
HEKLMFOH_00092 5.48e-204 - - - K - - - Helix-turn-helix XRE-family like proteins
HEKLMFOH_00093 0.0 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
HEKLMFOH_00094 1.33e-277 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HEKLMFOH_00095 3.15e-229 - - - S - - - Protein of unknown function (DUF2785)
HEKLMFOH_00096 3.22e-185 - - - O - - - Band 7 protein
HEKLMFOH_00097 2.71e-66 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
HEKLMFOH_00098 4.52e-282 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HEKLMFOH_00099 9.66e-46 - - - S - - - Protein of unknown function (DUF2969)
HEKLMFOH_00100 1.11e-69 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
HEKLMFOH_00101 4.82e-230 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
HEKLMFOH_00102 5e-310 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEKLMFOH_00103 1.11e-45 ywzB - - S - - - Protein of unknown function (DUF1146)
HEKLMFOH_00104 4.49e-88 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HEKLMFOH_00105 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HEKLMFOH_00106 1.07e-208 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HEKLMFOH_00107 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HEKLMFOH_00108 4.44e-117 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEKLMFOH_00109 6.29e-76 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HEKLMFOH_00110 7.38e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEKLMFOH_00111 1.55e-162 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HEKLMFOH_00112 1.3e-146 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HEKLMFOH_00113 4.47e-295 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HEKLMFOH_00114 4.74e-243 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HEKLMFOH_00115 4.34e-200 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HEKLMFOH_00116 2.77e-249 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HEKLMFOH_00117 7.63e-143 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HEKLMFOH_00118 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain
HEKLMFOH_00119 9.09e-173 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
HEKLMFOH_00120 8.97e-253 ampC - - V - - - Beta-lactamase
HEKLMFOH_00121 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
HEKLMFOH_00122 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
HEKLMFOH_00123 5.22e-75 - - - - - - - -
HEKLMFOH_00124 1.41e-122 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HEKLMFOH_00125 1.25e-59 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HEKLMFOH_00126 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
HEKLMFOH_00127 8e-186 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
HEKLMFOH_00128 1.93e-42 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
HEKLMFOH_00129 2.79e-141 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HEKLMFOH_00130 9.92e-172 - - - S ko:K07088 - ko00000 Membrane transport protein
HEKLMFOH_00131 1.26e-189 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
HEKLMFOH_00132 1.25e-137 citR - - K - - - Putative sugar-binding domain
HEKLMFOH_00133 4.5e-103 - - - I - - - Alpha/beta hydrolase family
HEKLMFOH_00134 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
HEKLMFOH_00135 2.95e-204 - - - K - - - helix_turn_helix, arabinose operon control protein
HEKLMFOH_00136 1.31e-267 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
HEKLMFOH_00137 1.18e-194 - - - K - - - LysR substrate binding domain
HEKLMFOH_00138 1.35e-208 - - - S - - - Conserved hypothetical protein 698
HEKLMFOH_00139 2.63e-128 cadD - - P - - - Cadmium resistance transporter
HEKLMFOH_00140 1e-69 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
HEKLMFOH_00141 0.0 sufI - - Q - - - Multicopper oxidase
HEKLMFOH_00142 3.01e-154 - - - S - - - SNARE associated Golgi protein
HEKLMFOH_00143 0.0 cadA - - P - - - P-type ATPase
HEKLMFOH_00144 1.81e-268 - - - M - - - Collagen binding domain
HEKLMFOH_00145 4.75e-92 - - - S - - - Iron-sulphur cluster biosynthesis
HEKLMFOH_00146 2.35e-80 - - - K - - - Transcriptional regulator, GntR family
HEKLMFOH_00147 0.0 - - - Q ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HEKLMFOH_00148 1.14e-175 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEKLMFOH_00149 3.04e-233 ydhF - - S - - - Aldo keto reductase
HEKLMFOH_00150 6.16e-264 ytbD - - EGP ko:K19577 - ko00000,ko02000 Major Facilitator
HEKLMFOH_00151 5.61e-82 ytcD - - K - - - Transcriptional regulator, HxlR family
HEKLMFOH_00152 1.11e-211 - - - - - - - -
HEKLMFOH_00153 0.0 tagB 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycerophosphotransferase
HEKLMFOH_00154 1.08e-94 - - - K - - - Transcriptional regulator
HEKLMFOH_00155 2.81e-197 - - - GM - - - NmrA-like family
HEKLMFOH_00156 3.5e-171 fabG1 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEKLMFOH_00157 3.67e-99 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HEKLMFOH_00158 3.04e-26 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HEKLMFOH_00159 3.64e-122 - - - S ko:K07090 - ko00000 membrane transporter protein
HEKLMFOH_00160 0.0 - - - E - - - dipeptidase activity
HEKLMFOH_00161 7.16e-40 - - - K - - - acetyltransferase
HEKLMFOH_00162 2.14e-60 - - - K - - - acetyltransferase
HEKLMFOH_00163 1.5e-183 lytE - - M - - - NlpC/P60 family
HEKLMFOH_00164 2.3e-96 - - - P - - - ArsC family
HEKLMFOH_00165 6.73e-317 - - - M - - - Parallel beta-helix repeats
HEKLMFOH_00166 1.7e-84 - - - K - - - MarR family
HEKLMFOH_00167 1.91e-193 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HEKLMFOH_00168 3.33e-204 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HEKLMFOH_00169 7.91e-192 galM1 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HEKLMFOH_00170 5.85e-56 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEKLMFOH_00171 3.12e-100 - - - - - - - -
HEKLMFOH_00172 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HEKLMFOH_00173 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HEKLMFOH_00174 3.99e-231 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
HEKLMFOH_00175 5.25e-313 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
HEKLMFOH_00176 4.29e-160 ciaR - - K ko:K14983 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 cheY-homologous receiver domain
HEKLMFOH_00177 0.0 - - - S - - - membrane
HEKLMFOH_00179 6.44e-138 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HEKLMFOH_00180 0.0 - - - S - - - C4-dicarboxylate anaerobic carrier
HEKLMFOH_00181 1.45e-296 ycbA 2.7.13.3 - T ko:K07706,ko:K07717 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 histidine kinase DNA gyrase B
HEKLMFOH_00182 8.69e-192 - - - KT ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 YcbB domain
HEKLMFOH_00183 0.0 arcD - - S - - - C4-dicarboxylate anaerobic carrier
HEKLMFOH_00184 0.0 arcT - - E - - - Dipeptidase
HEKLMFOH_00186 5.52e-265 - - - - - - - -
HEKLMFOH_00187 2.63e-137 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
HEKLMFOH_00188 1.08e-217 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HEKLMFOH_00189 7.38e-280 - - - U - - - Belongs to the major facilitator superfamily
HEKLMFOH_00190 5.12e-51 - - - S - - - Protein of unknown function (DUF3781)
HEKLMFOH_00191 4.28e-53 - - - - - - - -
HEKLMFOH_00192 1.17e-110 yafP - - K ko:K03830 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HEKLMFOH_00193 3.05e-169 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HEKLMFOH_00194 0.0 - - - M - - - domain protein
HEKLMFOH_00195 1.29e-239 ydbI - - K - - - AI-2E family transporter
HEKLMFOH_00196 4.09e-275 xylR - - GK - - - ROK family
HEKLMFOH_00197 4.7e-177 - - - - - - - -
HEKLMFOH_00198 9.8e-304 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
HEKLMFOH_00199 1.3e-71 - - - S - - - branched-chain amino acid
HEKLMFOH_00200 2.86e-176 azlC - - E - - - AzlC protein
HEKLMFOH_00201 1.6e-114 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
HEKLMFOH_00202 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
HEKLMFOH_00203 9.61e-41 - - - S ko:K21449 - ko00000,ko02000 Domain of unknown function (DUF4430)
HEKLMFOH_00204 1.11e-221 yhgE - - V ko:K01421 - ko00000 domain protein
HEKLMFOH_00205 7.64e-307 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HEKLMFOH_00206 2.39e-275 hpk31 - - T - - - Histidine kinase
HEKLMFOH_00207 4.64e-159 vanR - - K - - - response regulator
HEKLMFOH_00208 4.06e-267 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HEKLMFOH_00209 3.1e-138 - - - - - - - -
HEKLMFOH_00210 2.48e-170 - - - S - - - Protein of unknown function (DUF1129)
HEKLMFOH_00211 1.62e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HEKLMFOH_00212 1.15e-43 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
HEKLMFOH_00213 1.44e-199 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HEKLMFOH_00214 3.52e-176 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
HEKLMFOH_00215 5.86e-191 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HEKLMFOH_00216 2.3e-170 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
HEKLMFOH_00217 1.3e-209 - 3.1.4.17, 3.1.4.53 - S ko:K01120,ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
HEKLMFOH_00218 9.25e-217 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
HEKLMFOH_00219 1.1e-282 pbuO_1 - - S ko:K06901 - ko00000,ko02000 Permease family
HEKLMFOH_00220 8.91e-289 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
HEKLMFOH_00221 1.46e-198 - 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Metalloenzyme superfamily
HEKLMFOH_00222 6.14e-147 - - - GM - - - NmrA-like family
HEKLMFOH_00223 4.83e-59 - - - - - - - -
HEKLMFOH_00224 1.3e-124 - - - - - - - -
HEKLMFOH_00225 6.01e-54 - - - - - - - -
HEKLMFOH_00226 2.61e-83 - - - K - - - HxlR-like helix-turn-helix
HEKLMFOH_00228 7.78e-150 - - - - - - - -
HEKLMFOH_00229 0.0 - - - - - - - -
HEKLMFOH_00230 1.33e-132 - - - - - - - -
HEKLMFOH_00233 3.73e-239 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HEKLMFOH_00234 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HEKLMFOH_00235 5.36e-247 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HEKLMFOH_00236 1.92e-281 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HEKLMFOH_00237 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HEKLMFOH_00238 2.95e-50 - - - - - - - -
HEKLMFOH_00239 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HEKLMFOH_00240 1.61e-251 galM1 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HEKLMFOH_00241 2.25e-265 - 1.3.8.1, 1.3.8.7 - I ko:K00248,ko:K00249,ko:K18244 ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320 ko00000,ko00001,ko00002,ko01000 Acyl-CoA dehydrogenase, C-terminal domain
HEKLMFOH_00242 3.03e-186 fixA - - C ko:K03521 - ko00000 Electron transfer flavoprotein domain
HEKLMFOH_00243 1.74e-225 etfA 1.3.1.108 - C ko:K03522,ko:K22432 - ko00000,ko01000,ko04147 Electron transfer flavoprotein FAD-binding domain
HEKLMFOH_00244 4.7e-238 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
HEKLMFOH_00245 6.28e-73 - - - K - - - Transcriptional
HEKLMFOH_00246 8.73e-162 - - - S - - - DJ-1/PfpI family
HEKLMFOH_00247 0.0 - - - EP - - - Psort location Cytoplasmic, score
HEKLMFOH_00248 2.02e-106 - - - S - - - ASCH
HEKLMFOH_00249 0.0 - - - EGP - - - Major Facilitator
HEKLMFOH_00250 8.06e-33 - - - - - - - -
HEKLMFOH_00251 3.31e-195 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
HEKLMFOH_00252 4.18e-180 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HEKLMFOH_00253 4.89e-202 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
HEKLMFOH_00254 3.32e-154 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
HEKLMFOH_00255 1.01e-91 yeaO - - S - - - Protein of unknown function, DUF488
HEKLMFOH_00256 1.28e-161 - - - S - - - HAD-hyrolase-like
HEKLMFOH_00257 2.33e-103 - - - T - - - Universal stress protein family
HEKLMFOH_00258 0.0 - - - U ko:K03451 - ko00000 Belongs to the BCCT transporter (TC 2.A.15) family
HEKLMFOH_00259 3.21e-148 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
HEKLMFOH_00260 6.33e-109 - - - S ko:K04750 - ko00000 3-demethylubiquinone-9 3-methyltransferase
HEKLMFOH_00261 6.64e-190 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEKLMFOH_00262 1.89e-110 - - - - - - - -
HEKLMFOH_00263 3.08e-306 codA 3.5.4.1 - F ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000 cytosine deaminase
HEKLMFOH_00264 1.12e-64 - - - - - - - -
HEKLMFOH_00265 9.11e-196 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HEKLMFOH_00266 8.02e-25 - - - - - - - -
HEKLMFOH_00267 6.1e-160 yrkL - - S - - - Flavodoxin-like fold
HEKLMFOH_00269 1.24e-44 - - - - - - - -
HEKLMFOH_00271 3.1e-51 - - - S - - - Cytochrome B5
HEKLMFOH_00272 2.32e-43 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HEKLMFOH_00273 1.47e-144 mhqD - - S ko:K06999 - ko00000 Dienelactone hydrolase family
HEKLMFOH_00274 2.63e-69 - - - - - - - -
HEKLMFOH_00275 2.32e-282 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
HEKLMFOH_00276 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HEKLMFOH_00277 0.0 - - - M - - - domain, Protein
HEKLMFOH_00278 2.56e-70 - - - - - - - -
HEKLMFOH_00279 3.24e-250 - 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
HEKLMFOH_00280 3.46e-87 - - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
HEKLMFOH_00281 7.22e-237 tas - - C - - - Aldo/keto reductase family
HEKLMFOH_00282 1.49e-43 - - - - - - - -
HEKLMFOH_00283 3.65e-226 - - - EG - - - EamA-like transporter family
HEKLMFOH_00284 2.02e-147 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HEKLMFOH_00285 1.87e-248 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HEKLMFOH_00286 2.8e-188 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HEKLMFOH_00287 9.75e-131 tag2 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
HEKLMFOH_00288 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HEKLMFOH_00290 0.0 - 3.2.1.21, 3.2.1.52 GH3 G ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501 ko00000,ko00001,ko00002,ko01000 hydrolase, family 3
HEKLMFOH_00291 1.34e-109 lytE - - M - - - NlpC P60 family
HEKLMFOH_00292 2.94e-236 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HEKLMFOH_00293 5.95e-147 - - - - - - - -
HEKLMFOH_00294 5.19e-133 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HEKLMFOH_00295 5.64e-144 nnrE 5.1.99.6 - H ko:K17759 - ko00000,ko01000 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HEKLMFOH_00296 1.11e-100 - - - K ko:K06075 - ko00000,ko03000 Winged helix DNA-binding domain
HEKLMFOH_00297 8.74e-69 - - - - - - - -
HEKLMFOH_00299 6.65e-269 - - - S ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
HEKLMFOH_00300 5.02e-29 - - - S - - - SEC-C Motif Domain Protein
HEKLMFOH_00302 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HEKLMFOH_00303 0.0 - - - E - - - Amino acid permease
HEKLMFOH_00304 3.43e-204 nanK - - GK - - - ROK family
HEKLMFOH_00305 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HEKLMFOH_00306 2.21e-253 - - - S - - - DUF218 domain
HEKLMFOH_00307 1.86e-210 - - - - - - - -
HEKLMFOH_00308 9.09e-97 - - - K - - - Transcriptional regulator
HEKLMFOH_00309 0.0 pepF2 - - E - - - Oligopeptidase F
HEKLMFOH_00310 9.03e-229 ybcH - - D ko:K06889 - ko00000 Alpha beta
HEKLMFOH_00311 1.9e-164 - - - S - - - Protein of unknown function (DUF1275)
HEKLMFOH_00312 0.0 cpdB - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HEKLMFOH_00313 5.68e-316 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
HEKLMFOH_00314 4.04e-204 - - - C - - - Aldo keto reductase
HEKLMFOH_00315 2.33e-282 xylR - - GK - - - ROK family
HEKLMFOH_00316 7.43e-171 - - - K - - - helix_turn_helix, mercury resistance
HEKLMFOH_00317 8.37e-178 XK27_00890 - - S ko:K08974 - ko00000 Domain of unknown function (DUF368)
HEKLMFOH_00318 2.24e-101 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
HEKLMFOH_00319 7.28e-38 - - - K - - - Helix-turn-helix XRE-family like proteins
HEKLMFOH_00325 7.04e-118 - - - - - - - -
HEKLMFOH_00326 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEKLMFOH_00327 6.15e-153 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEKLMFOH_00328 3.91e-167 yjkA - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
HEKLMFOH_00329 6.12e-193 yneD - - S - - - Enoyl-(Acyl carrier protein) reductase
HEKLMFOH_00330 3.12e-178 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HEKLMFOH_00331 2.91e-190 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HEKLMFOH_00332 9.74e-146 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HEKLMFOH_00333 2.81e-44 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEKLMFOH_00334 2.29e-285 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEKLMFOH_00335 4.9e-246 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
HEKLMFOH_00336 7.36e-74 - - - - - - - -
HEKLMFOH_00337 1.24e-86 - - - - - - - -
HEKLMFOH_00338 2.06e-259 - - - - - - - -
HEKLMFOH_00339 6.58e-130 - - - K - - - DNA-templated transcription, initiation
HEKLMFOH_00340 1.99e-36 - - - - - - - -
HEKLMFOH_00342 1.08e-214 - - - K - - - LysR substrate binding domain
HEKLMFOH_00343 9.17e-284 - - - EK - - - Aminotransferase, class I
HEKLMFOH_00344 2.45e-103 - 3.2.1.23, 3.2.1.89 - G ko:K01190,ko:K01224 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 arabinogalactan endo-1,4-beta-galactosidase activity
HEKLMFOH_00345 1.61e-44 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
HEKLMFOH_00346 2.61e-49 ynzC - - S - - - UPF0291 protein
HEKLMFOH_00347 2.41e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HEKLMFOH_00348 2.76e-99 - - - F - - - nucleoside 2-deoxyribosyltransferase
HEKLMFOH_00349 2.02e-114 - - - - - - - -
HEKLMFOH_00350 3.15e-276 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
HEKLMFOH_00351 1.72e-211 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
HEKLMFOH_00352 2.82e-160 pgm3 - - G - - - phosphoglycerate mutase
HEKLMFOH_00353 2.94e-34 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
HEKLMFOH_00354 2.06e-107 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
HEKLMFOH_00358 4.78e-91 - - - S - - - TIR domain
HEKLMFOH_00359 1.12e-213 - - - I - - - Diacylglycerol kinase catalytic domain
HEKLMFOH_00360 5.89e-98 - - - - - - - -
HEKLMFOH_00361 6.11e-11 - - - K - - - CsbD-like
HEKLMFOH_00362 7.24e-102 - - - T - - - Universal stress protein family
HEKLMFOH_00363 3.06e-120 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HEKLMFOH_00364 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HEKLMFOH_00365 4.43e-72 yrvD - - S - - - Pfam:DUF1049
HEKLMFOH_00366 1.19e-230 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HEKLMFOH_00367 1.36e-37 - - - - - - - -
HEKLMFOH_00368 2.51e-158 - - - - - - - -
HEKLMFOH_00369 2.41e-315 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HEKLMFOH_00370 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HEKLMFOH_00371 1.21e-22 - - - - - - - -
HEKLMFOH_00372 4.51e-69 - - - S - - - mazG nucleotide pyrophosphohydrolase
HEKLMFOH_00373 3.22e-141 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HEKLMFOH_00374 5.91e-298 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HEKLMFOH_00375 1.02e-298 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HEKLMFOH_00376 9.97e-288 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HEKLMFOH_00377 2.17e-213 - - - S - - - Tetratricopeptide repeat
HEKLMFOH_00378 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEKLMFOH_00379 2.9e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HEKLMFOH_00380 8e-45 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HEKLMFOH_00381 1.99e-237 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HEKLMFOH_00382 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HEKLMFOH_00383 6.1e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
HEKLMFOH_00384 1.22e-155 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
HEKLMFOH_00385 8.32e-254 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HEKLMFOH_00386 1.05e-108 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HEKLMFOH_00387 6.8e-129 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
HEKLMFOH_00388 2.3e-58 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
HEKLMFOH_00389 3.1e-269 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HEKLMFOH_00390 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HEKLMFOH_00391 1.33e-184 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
HEKLMFOH_00392 7.2e-61 yktA - - S - - - Belongs to the UPF0223 family
HEKLMFOH_00393 1.16e-209 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 L-malate dehydrogenase activity
HEKLMFOH_00394 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
HEKLMFOH_00395 1.21e-287 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEKLMFOH_00396 1.15e-232 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
HEKLMFOH_00397 4.77e-271 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
HEKLMFOH_00398 9.7e-133 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HEKLMFOH_00399 9.18e-105 - - - - - - - -
HEKLMFOH_00400 9.82e-45 ykzG - - S - - - Belongs to the UPF0356 family
HEKLMFOH_00401 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEKLMFOH_00402 2.84e-239 - - - I - - - Diacylglycerol kinase catalytic
HEKLMFOH_00403 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
HEKLMFOH_00404 1.21e-302 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEKLMFOH_00405 3.24e-57 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HEKLMFOH_00406 8.23e-157 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
HEKLMFOH_00410 2.52e-97 - - - S - - - Leucine-rich repeat (LRR) protein
HEKLMFOH_00413 3.13e-46 - - - S - - - WxL domain surface cell wall-binding
HEKLMFOH_00415 2.44e-113 - - - S - - - Cell surface protein
HEKLMFOH_00416 6.23e-127 XK27_00720 - - S ko:K13730 ko05100,map05100 ko00000,ko00001 regulation of response to stimulus
HEKLMFOH_00417 7.98e-313 - - - S - - - Leucine-rich repeat (LRR) protein
HEKLMFOH_00418 4.67e-114 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEKLMFOH_00419 2.17e-127 lemA - - S ko:K03744 - ko00000 LemA family
HEKLMFOH_00420 6.57e-198 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HEKLMFOH_00421 1.91e-192 - - - - - - - -
HEKLMFOH_00422 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HEKLMFOH_00423 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HEKLMFOH_00424 1.23e-273 - - - S - - - nuclear-transcribed mRNA catabolic process, no-go decay
HEKLMFOH_00425 9.61e-84 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HEKLMFOH_00426 1.74e-274 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HEKLMFOH_00428 1.45e-80 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HEKLMFOH_00429 1.06e-147 - - - S - - - (CBS) domain
HEKLMFOH_00431 0.0 - - - S - - - Putative peptidoglycan binding domain
HEKLMFOH_00432 5.62e-225 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HEKLMFOH_00433 1.28e-132 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HEKLMFOH_00434 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HEKLMFOH_00435 0.0 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HEKLMFOH_00436 7.09e-53 yabO - - J - - - S4 domain protein
HEKLMFOH_00437 9.05e-58 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
HEKLMFOH_00438 4.64e-124 yabR - - J ko:K07571 - ko00000 RNA binding
HEKLMFOH_00439 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HEKLMFOH_00440 5.23e-125 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HEKLMFOH_00441 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HEKLMFOH_00442 2.74e-209 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HEKLMFOH_00443 2.56e-248 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEKLMFOH_00444 3.52e-189 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
HEKLMFOH_00445 3.52e-172 - - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 protein conserved in bacteria
HEKLMFOH_00446 1.28e-129 - - - S - - - Putative glutamine amidotransferase
HEKLMFOH_00447 1.32e-119 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HEKLMFOH_00448 0.0 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
HEKLMFOH_00449 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HEKLMFOH_00450 5.16e-115 - - - - - - - -
HEKLMFOH_00451 1.47e-74 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
HEKLMFOH_00453 2.26e-33 - - - - - - - -
HEKLMFOH_00454 3.21e-104 - - - O - - - OsmC-like protein
HEKLMFOH_00455 2.39e-34 - - - - - - - -
HEKLMFOH_00456 8.55e-99 - - - K - - - Transcriptional regulator
HEKLMFOH_00457 3.85e-116 - - - S - - - Domain of unknown function (DUF5067)
HEKLMFOH_00458 1.51e-195 - - - M ko:K07271 - ko00000,ko01000 LicD family
HEKLMFOH_00459 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HEKLMFOH_00460 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HEKLMFOH_00461 8.23e-219 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HEKLMFOH_00462 3.16e-182 fepC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HEKLMFOH_00463 1.42e-220 isdF - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEKLMFOH_00464 1.12e-209 isdE - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
HEKLMFOH_00465 9.62e-154 - - - M ko:K14193 ko05150,map05150 ko00000,ko00001 Iron Transport-associated domain
HEKLMFOH_00466 8.61e-257 - - - M - - - Iron Transport-associated domain
HEKLMFOH_00467 1.61e-135 - - - S - - - Iron Transport-associated domain
HEKLMFOH_00468 3.14e-66 - - - - - - - -
HEKLMFOH_00469 2.31e-257 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HEKLMFOH_00470 2.09e-45 copZ - - P - - - Heavy-metal-associated domain
HEKLMFOH_00471 4.81e-127 dpsB - - P - - - Belongs to the Dps family
HEKLMFOH_00472 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
HEKLMFOH_00473 0.0 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HEKLMFOH_00474 4.46e-167 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HEKLMFOH_00475 3.46e-18 - - - - - - - -
HEKLMFOH_00476 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HEKLMFOH_00477 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HEKLMFOH_00478 2.55e-191 ybbR - - S - - - YbbR-like protein
HEKLMFOH_00479 5.67e-196 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HEKLMFOH_00480 1.34e-158 - - - S - - - Protein of unknown function (DUF1361)
HEKLMFOH_00481 0.0 yvgP - - P ko:K03316 - ko00000 Sodium proton antiporter
HEKLMFOH_00482 2.34e-210 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
HEKLMFOH_00483 4.03e-195 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HEKLMFOH_00484 6.15e-132 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HEKLMFOH_00485 8.93e-249 tas3 - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
HEKLMFOH_00486 1.15e-115 - - - J - - - Acetyltransferase (GNAT) domain
HEKLMFOH_00487 7.73e-109 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
HEKLMFOH_00488 4.83e-229 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
HEKLMFOH_00489 2.24e-180 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HEKLMFOH_00490 1.04e-133 - - - - - - - -
HEKLMFOH_00492 4.9e-126 - - - I - - - NUDIX domain
HEKLMFOH_00493 1.4e-147 yviA - - S - - - Protein of unknown function (DUF421)
HEKLMFOH_00494 2.17e-97 - - - S - - - Protein of unknown function (DUF3290)
HEKLMFOH_00495 5.79e-215 ropB - - K - - - Helix-turn-helix XRE-family like proteins
HEKLMFOH_00496 1.99e-281 - - - EGP - - - Transmembrane secretion effector
HEKLMFOH_00497 0.0 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
HEKLMFOH_00498 2.98e-49 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
HEKLMFOH_00500 1.68e-257 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HEKLMFOH_00501 5.37e-48 - - - - - - - -
HEKLMFOH_00502 1.82e-175 - - - G - - - Xylose isomerase domain protein TIM barrel
HEKLMFOH_00503 5.08e-291 gntT - - EG - - - Citrate transporter
HEKLMFOH_00504 3.39e-227 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 pfkB family carbohydrate kinase
HEKLMFOH_00505 5.45e-138 - 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Orotidine 5'-phosphate decarboxylase HUMPS family
HEKLMFOH_00506 2.02e-113 hxlB 5.3.1.27 - M ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 sugar phosphate isomerase involved in capsule formation
HEKLMFOH_00507 2.57e-226 kdgR - - K ko:K02525 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HEKLMFOH_00508 3.57e-72 - - - - - - - -
HEKLMFOH_00509 6.94e-110 - - - - - - - -
HEKLMFOH_00510 0.0 - - - L - - - DNA helicase
HEKLMFOH_00511 1.16e-243 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HEKLMFOH_00512 5.35e-217 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HEKLMFOH_00513 5.82e-290 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
HEKLMFOH_00514 8.05e-231 - - - - - - - -
HEKLMFOH_00515 8.39e-168 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
HEKLMFOH_00516 8.41e-67 - - - - - - - -
HEKLMFOH_00517 2.54e-207 yunF - - F - - - Protein of unknown function DUF72
HEKLMFOH_00518 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HEKLMFOH_00519 1.63e-187 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
HEKLMFOH_00520 9.98e-128 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HEKLMFOH_00521 5.72e-207 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HEKLMFOH_00522 1.14e-48 veg - - S - - - Biofilm formation stimulator VEG
HEKLMFOH_00523 3.2e-207 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HEKLMFOH_00524 4.6e-143 ung2 - - L - - - Uracil-DNA glycosylase
HEKLMFOH_00525 0.0 yicI 3.2.1.177 GH31 G ko:K01811 - ko00000,ko01000 Belongs to the glycosyl hydrolase 31 family
HEKLMFOH_00526 0.0 xylP - - G ko:K03292 - ko00000 MFS/sugar transport protein
HEKLMFOH_00527 1.04e-268 xylR - - GK - - - ROK family
HEKLMFOH_00528 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HEKLMFOH_00529 3.71e-207 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HEKLMFOH_00530 3.78e-114 - - - - - - - -
HEKLMFOH_00532 2.94e-217 - - - S ko:K06889 - ko00000 Prolyl oligopeptidase family
HEKLMFOH_00533 1.37e-220 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HEKLMFOH_00534 7.18e-169 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HEKLMFOH_00535 2.09e-173 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
HEKLMFOH_00537 1.95e-186 - - - M - - - Leucine-rich repeat (LRR) protein
HEKLMFOH_00538 1.64e-88 - - - M - - - LysM domain protein
HEKLMFOH_00540 3.71e-76 lysM - - M - - - LysM domain
HEKLMFOH_00542 1.38e-126 - - - K - - - Bacterial regulatory proteins, tetR family
HEKLMFOH_00543 8.22e-213 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HEKLMFOH_00544 1.49e-224 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 pfkB family carbohydrate kinase
HEKLMFOH_00545 2.13e-277 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HEKLMFOH_00546 9.44e-82 - - - S - - - 3D domain
HEKLMFOH_00547 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
HEKLMFOH_00548 1.21e-213 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HEKLMFOH_00549 1.76e-153 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HEKLMFOH_00550 2.56e-300 - - - V - - - MatE
HEKLMFOH_00551 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
HEKLMFOH_00552 0.0 - - - G ko:K03292 - ko00000 MFS/sugar transport protein
HEKLMFOH_00553 0.0 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
HEKLMFOH_00554 1.03e-207 - - - EG ko:K16321 - ko00000,ko02000 GntP family permease
HEKLMFOH_00555 1.7e-104 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
HEKLMFOH_00556 2.17e-135 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 pfkB family carbohydrate kinase
HEKLMFOH_00557 5.33e-305 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
HEKLMFOH_00558 1.34e-45 - - - - - - - -
HEKLMFOH_00559 0.0 uxuT - - G ko:K03292,ko:K16210 - ko00000,ko02000 MFS/sugar transport protein
HEKLMFOH_00560 7.56e-119 kdgR - - K - - - FCD domain
HEKLMFOH_00561 1.02e-256 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
HEKLMFOH_00562 0.0 uxuB 1.1.1.57 - G ko:K00040 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Mannitol dehydrogenase C-terminal domain
HEKLMFOH_00563 7.04e-215 yqhA - - G - - - Aldose 1-epimerase
HEKLMFOH_00564 3.17e-157 - - - G - - - Belongs to the phosphoglycerate mutase family
HEKLMFOH_00565 1.41e-240 - - - C - - - Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEKLMFOH_00566 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HEKLMFOH_00567 2.36e-217 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
HEKLMFOH_00568 3.03e-166 - - - K - - - FCD domain
HEKLMFOH_00569 1.04e-271 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
HEKLMFOH_00570 7.78e-236 exuR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein domain
HEKLMFOH_00571 0.0 - - - G ko:K03292 - ko00000 MFS/sugar transport protein
HEKLMFOH_00572 0.0 - 5.1.2.7 - S ko:K21619 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 tagaturonate epimerase
HEKLMFOH_00573 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
HEKLMFOH_00574 1.34e-296 - - - S - - - module of peptide synthetase
HEKLMFOH_00576 0.0 - - - EGP - - - Major Facilitator
HEKLMFOH_00579 2.65e-177 - - - - - - - -
HEKLMFOH_00580 1.42e-118 ebsC - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HEKLMFOH_00581 3.02e-170 gntR1 - - K - - - UbiC transcription regulator-associated domain protein
HEKLMFOH_00582 4.33e-161 zmp3 - - O - - - Zinc-dependent metalloprotease
HEKLMFOH_00583 1.68e-109 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HEKLMFOH_00584 6.37e-102 - - - - - - - -
HEKLMFOH_00585 2.4e-181 agrA - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HEKLMFOH_00586 1.53e-304 pltK 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HEKLMFOH_00587 2.35e-303 - - - T - - - protein histidine kinase activity
HEKLMFOH_00588 3.97e-173 - - - IQ - - - Oxidoreductase, short chain dehydrogenase reductase family protein
HEKLMFOH_00590 1.79e-214 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HEKLMFOH_00591 1.4e-99 uspA3 - - T - - - universal stress protein
HEKLMFOH_00592 1.36e-132 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEKLMFOH_00593 2.76e-115 - - - EGP - - - Major Facilitator
HEKLMFOH_00594 4.91e-88 - - - EGP - - - Major Facilitator
HEKLMFOH_00595 5.02e-16 - - - K - - - transcriptional regulator
HEKLMFOH_00596 2.7e-68 - - - K - - - transcriptional regulator
HEKLMFOH_00597 0.0 oppA1 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HEKLMFOH_00598 3.95e-224 oppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEKLMFOH_00599 1.14e-229 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HEKLMFOH_00600 8.35e-230 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HEKLMFOH_00601 6.49e-245 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HEKLMFOH_00602 6.65e-104 - - - K - - - Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HEKLMFOH_00603 1.05e-250 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
HEKLMFOH_00604 8.07e-91 - - - - - - - -
HEKLMFOH_00605 3.3e-63 - - - - - - - -
HEKLMFOH_00606 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
HEKLMFOH_00607 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Xylulose kinase
HEKLMFOH_00608 4.03e-288 xylT - - EGP - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEKLMFOH_00610 7.71e-182 budC 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
HEKLMFOH_00611 1.52e-90 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
HEKLMFOH_00612 0.0 - - - S - - - membrane
HEKLMFOH_00613 6.41e-118 usp5 - - T - - - universal stress protein
HEKLMFOH_00614 2.26e-125 yxkA - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
HEKLMFOH_00615 8.35e-277 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HEKLMFOH_00616 1.35e-162 - - - P ko:K10716 - ko00000,ko02000 Ion channel
HEKLMFOH_00617 2.16e-77 - - - - - - - -
HEKLMFOH_00618 2.53e-216 - - - C - - - Aldo keto reductase
HEKLMFOH_00619 3.82e-91 - - - - - - - -
HEKLMFOH_00620 1.9e-121 - - - S - - - Acetyltransferase (GNAT) family
HEKLMFOH_00621 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HEKLMFOH_00622 1.78e-243 - - - S ko:K07088 - ko00000 Membrane transport protein
HEKLMFOH_00623 3.08e-241 idhA 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEKLMFOH_00624 0.0 yufL 2.7.13.3 - T ko:K02476,ko:K11614 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Single cache domain 3
HEKLMFOH_00625 6.8e-161 dctR - - K ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 cheY-homologous receiver domain
HEKLMFOH_00626 4.86e-118 - - - S - - - ABC-2 family transporter protein
HEKLMFOH_00627 7.62e-110 - - - S - - - ABC-2 family transporter protein
HEKLMFOH_00628 8.88e-132 - - - K - - - Bacterial regulatory proteins, tetR family
HEKLMFOH_00629 1.64e-158 - - - T - - - Putative diguanylate phosphodiesterase
HEKLMFOH_00630 2.24e-123 - - - K - - - Acetyltransferase (GNAT) family
HEKLMFOH_00631 8.47e-184 - - - S - - - zinc-ribbon domain
HEKLMFOH_00632 0.0 - - - S - - - response to antibiotic
HEKLMFOH_00634 1.29e-110 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
HEKLMFOH_00636 7.47e-133 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
HEKLMFOH_00637 1.64e-108 padR - - K - - - Virulence activator alpha C-term
HEKLMFOH_00638 2.28e-132 - - - K - - - Bacterial regulatory proteins, tetR family
HEKLMFOH_00639 1.25e-239 - 1.1.1.219 - GM ko:K00091 - ko00000,ko01000 Male sterility protein
HEKLMFOH_00640 5.15e-100 - - - S ko:K02348 - ko00000 Gnat family
HEKLMFOH_00641 5.75e-103 yybA - - K - - - Transcriptional regulator
HEKLMFOH_00642 1.83e-96 - - - - - - - -
HEKLMFOH_00643 5.74e-120 - - - - - - - -
HEKLMFOH_00644 2.87e-126 - - - P - - - Cadmium resistance transporter
HEKLMFOH_00645 4.7e-157 - - - K ko:K03709 - ko00000,ko03000 Helix-turn-helix diphteria tox regulatory element
HEKLMFOH_00646 2.77e-94 usp1 - - T - - - Universal stress protein family
HEKLMFOH_00647 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HEKLMFOH_00648 4.91e-240 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HEKLMFOH_00649 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HEKLMFOH_00650 6.84e-311 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HEKLMFOH_00651 2.16e-126 - - - K - - - Bacterial regulatory proteins, tetR family
HEKLMFOH_00652 1.19e-231 - - - D ko:K06889 - ko00000 Alpha beta
HEKLMFOH_00653 3.29e-190 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HEKLMFOH_00654 1.36e-213 - - - I - - - Alpha beta
HEKLMFOH_00655 0.0 - - - O - - - Pro-kumamolisin, activation domain
HEKLMFOH_00656 5.87e-154 - - - S - - - Membrane
HEKLMFOH_00657 9.76e-173 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
HEKLMFOH_00658 8.04e-49 - - - - - - - -
HEKLMFOH_00659 3e-146 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
HEKLMFOH_00660 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HEKLMFOH_00661 2.05e-256 - - - M - - - NlpC/P60 family
HEKLMFOH_00662 1.36e-211 - - - G - - - Peptidase_C39 like family
HEKLMFOH_00663 9.2e-300 - 3.2.1.21, 3.2.1.52 GH3 G ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501 ko00000,ko00001,ko00002,ko01000 Fibronectin type III-like domain
HEKLMFOH_00664 1e-99 - - - K - - - AraC-like ligand binding domain
HEKLMFOH_00665 4.67e-307 lacZ3 3.2.1.23 - G ko:K01190,ko:K12308 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Beta-galactosidase trimerisation domain
HEKLMFOH_00666 4.82e-196 - - - G - - - MFS/sugar transport protein
HEKLMFOH_00667 3.02e-270 srfJ1 3.2.1.45 GH30 M ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 30 family
HEKLMFOH_00668 4.14e-137 pncA - - Q - - - Isochorismatase family
HEKLMFOH_00669 3.74e-73 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
HEKLMFOH_00670 1.89e-120 - - - S - - - Protein of unknown function (DUF1700)
HEKLMFOH_00671 4.97e-206 - - - S - - - Putative adhesin
HEKLMFOH_00672 1.03e-238 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEKLMFOH_00673 9.22e-288 fabV 1.3.1.44, 1.3.1.9 - I ko:K00209 ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 NAD(P)H binding domain of trans-2-enoyl-CoA reductase
HEKLMFOH_00674 6.75e-96 - - - C - - - Flavodoxin
HEKLMFOH_00675 2.42e-127 - - - K - - - Acetyltransferase (GNAT) domain
HEKLMFOH_00676 7.74e-315 yifK - - E ko:K03293 - ko00000 Amino acid permease
HEKLMFOH_00677 6.88e-152 - - - - - - - -
HEKLMFOH_00678 4.04e-136 - - - S - - - WxL domain surface cell wall-binding
HEKLMFOH_00679 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
HEKLMFOH_00680 1.53e-285 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HEKLMFOH_00681 1.07e-238 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HEKLMFOH_00682 3.05e-90 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
HEKLMFOH_00683 2.83e-209 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HEKLMFOH_00684 0.0 - - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HEKLMFOH_00685 7.55e-265 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HEKLMFOH_00686 1.33e-129 - - - S - - - NADPH-dependent FMN reductase
HEKLMFOH_00687 4.76e-111 - - - K - - - MarR family
HEKLMFOH_00688 0.0 pacL1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HEKLMFOH_00690 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HEKLMFOH_00691 1.99e-195 - - - - - - - -
HEKLMFOH_00692 2.99e-136 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
HEKLMFOH_00693 4.18e-155 - - - S - - - Elongation factor G-binding protein, N-terminal
HEKLMFOH_00694 8.25e-217 - - - EG - - - EamA-like transporter family
HEKLMFOH_00695 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HEKLMFOH_00696 1.72e-103 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
HEKLMFOH_00697 2.57e-290 dacA2 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HEKLMFOH_00698 6.98e-205 morA - - S - - - reductase
HEKLMFOH_00699 0.0 copA 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HEKLMFOH_00700 9.96e-82 - - - S - - - Cupredoxin-like domain
HEKLMFOH_00702 1.64e-187 icaB - - G - - - Polysaccharide deacetylase
HEKLMFOH_00703 1.41e-205 - - - L - - - Phage integrase, N-terminal SAM-like domain
HEKLMFOH_00704 8.54e-246 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HEKLMFOH_00705 0.0 oatA - - I - - - Acyltransferase
HEKLMFOH_00706 5.46e-157 - - - - - - - -
HEKLMFOH_00707 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
HEKLMFOH_00708 3.35e-137 - 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HEKLMFOH_00709 1.38e-89 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HEKLMFOH_00710 8.9e-51 - - - - - - - -
HEKLMFOH_00711 4.44e-122 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HEKLMFOH_00712 9.38e-317 xylP1 - - G ko:K03292 - ko00000 MFS/sugar transport protein
HEKLMFOH_00713 1.16e-129 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
HEKLMFOH_00714 0.0 uvrA2 - - L - - - ABC transporter
HEKLMFOH_00715 5.02e-87 yodA - - S - - - Tautomerase enzyme
HEKLMFOH_00716 0.0 - - - - - - - -
HEKLMFOH_00717 7.3e-303 - - - - - - - -
HEKLMFOH_00718 3.23e-141 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEKLMFOH_00719 3.01e-225 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HEKLMFOH_00720 1.39e-136 opuCB - - E ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HEKLMFOH_00721 2.09e-287 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HEKLMFOH_00722 3.61e-59 - - - - - - - -
HEKLMFOH_00723 2.53e-283 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
HEKLMFOH_00724 1.06e-233 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
HEKLMFOH_00725 1.66e-291 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
HEKLMFOH_00726 1.98e-165 - - - M - - - Protein of unknown function (DUF3737)
HEKLMFOH_00727 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HEKLMFOH_00728 2.37e-248 ykoT - - M - - - Glycosyl transferase family 2
HEKLMFOH_00729 0.0 - - - M ko:K07273 - ko00000 hydrolase, family 25
HEKLMFOH_00730 2.58e-139 - - - - - - - -
HEKLMFOH_00731 1.3e-264 XK27_05220 - - S - - - AI-2E family transporter
HEKLMFOH_00732 1.83e-276 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HEKLMFOH_00733 1.45e-157 vex2 - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HEKLMFOH_00734 0.0 malL 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HEKLMFOH_00735 2.16e-75 - - - K - - - Winged helix-turn-helix DNA-binding
HEKLMFOH_00736 1.5e-179 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
HEKLMFOH_00737 9.85e-208 - - - P - - - CorA-like Mg2+ transporter protein
HEKLMFOH_00738 0.0 pox2 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HEKLMFOH_00739 3.7e-96 - - - - - - - -
HEKLMFOH_00740 3.02e-57 - - - - - - - -
HEKLMFOH_00741 2.93e-314 hpk2 - - T - - - Histidine kinase
HEKLMFOH_00742 2.22e-168 rrp2 - - K - - - Transcriptional regulatory protein, C terminal
HEKLMFOH_00743 2.54e-52 - - - - - - - -
HEKLMFOH_00744 2.61e-148 - - - GM - - - NAD(P)H-binding
HEKLMFOH_00745 2.28e-292 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HEKLMFOH_00746 9.52e-124 ogt 2.1.1.63 - L ko:K00567 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HEKLMFOH_00747 1.61e-132 - - - K - - - Bacterial regulatory proteins, tetR family
HEKLMFOH_00748 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HEKLMFOH_00749 1.36e-128 - - - K - - - Bacterial transcriptional regulator
HEKLMFOH_00750 5.76e-65 - - - G - - - Xylose isomerase domain protein TIM barrel
HEKLMFOH_00751 3.4e-07 - - - - - - - -
HEKLMFOH_00752 2.27e-185 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HEKLMFOH_00753 8.48e-176 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEKLMFOH_00754 6.39e-164 kdgT - - P ko:K02526 - ko00000,ko02000 2-keto-3-deoxygluconate permease
HEKLMFOH_00755 1.3e-138 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 pfkB family carbohydrate kinase
HEKLMFOH_00756 2.71e-103 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
HEKLMFOH_00757 1.77e-50 - - - - - - - -
HEKLMFOH_00758 3.62e-166 - 1.1.1.53 - IQ ko:K00038 ko00140,ko01100,map00140,map01100 ko00000,ko00001,ko01000 reductase
HEKLMFOH_00759 1.8e-306 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HEKLMFOH_00760 1.1e-198 degV - - S - - - Uncharacterised protein, DegV family COG1307
HEKLMFOH_00761 0.0 nox - - C - - - NADH oxidase
HEKLMFOH_00762 6.89e-75 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HEKLMFOH_00763 2.72e-51 yrkD - - S - - - Metal-sensitive transcriptional repressor
HEKLMFOH_00764 3.13e-86 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEKLMFOH_00765 2.22e-78 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEKLMFOH_00766 8.33e-193 - - - - - - - -
HEKLMFOH_00767 9.97e-211 - - - I - - - Carboxylesterase family
HEKLMFOH_00768 1.44e-113 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HEKLMFOH_00769 2.67e-209 - - - - - - - -
HEKLMFOH_00770 0.0 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEKLMFOH_00771 1.08e-216 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HEKLMFOH_00772 2.62e-202 lysR5 - - K - - - LysR substrate binding domain
HEKLMFOH_00773 6.5e-185 - - - S ko:K07090 - ko00000 membrane transporter protein
HEKLMFOH_00774 2.07e-75 - - - S - - - Protein of unknown function (DUF1634)
HEKLMFOH_00775 7.15e-179 - - - IQ - - - Oxidoreductase, short chain dehydrogenase reductase family protein
HEKLMFOH_00776 1.56e-294 mdtG - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
HEKLMFOH_00777 7.03e-22 - - - T - - - Region found in RelA / SpoT proteins
HEKLMFOH_00778 1.12e-42 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
HEKLMFOH_00779 2.36e-38 - - - S - - - Protein of unknown function (DUF2929)
HEKLMFOH_00781 2.47e-74 - - - S - - - Protein of unknown function (DUF2975)
HEKLMFOH_00782 6.21e-39 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
HEKLMFOH_00783 1.71e-284 - - - - - - - -
HEKLMFOH_00784 1.41e-136 - - - - - - - -
HEKLMFOH_00785 4.14e-259 icaA - - M - - - Glycosyl transferase family group 2
HEKLMFOH_00786 5.82e-73 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HEKLMFOH_00787 3.1e-143 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HEKLMFOH_00788 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEKLMFOH_00789 3.09e-133 - - - K - - - Psort location Cytoplasmic, score
HEKLMFOH_00790 8.26e-92 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEKLMFOH_00791 6.09e-53 - - - S - - - Mor transcription activator family
HEKLMFOH_00792 2.33e-56 - - - S - - - Mor transcription activator family
HEKLMFOH_00793 6.64e-162 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
HEKLMFOH_00795 9.32e-165 ybhF_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HEKLMFOH_00796 9.15e-250 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HEKLMFOH_00797 3.16e-144 - - - K - - - Bacterial regulatory proteins, tetR family
HEKLMFOH_00798 1.24e-225 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HEKLMFOH_00799 1.45e-78 - - - S - - - Belongs to the HesB IscA family
HEKLMFOH_00800 3.19e-210 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
HEKLMFOH_00802 8.88e-39 yycB - - P ko:K03449 - ko00000,ko02000 Major Facilitator Superfamily
HEKLMFOH_00803 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
HEKLMFOH_00804 8.1e-236 - - - C - - - Zinc-binding dehydrogenase
HEKLMFOH_00805 5.39e-23 - - - GM - - - Male sterility protein
HEKLMFOH_00806 5.8e-92 - - - GM - - - Male sterility protein
HEKLMFOH_00807 3.48e-103 - - - K - - - helix_turn_helix, mercury resistance
HEKLMFOH_00808 1.61e-87 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 MarR family
HEKLMFOH_00809 1.57e-65 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2316)
HEKLMFOH_00810 1.97e-253 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HEKLMFOH_00811 6.61e-96 - - - K - - - Transcriptional regulator
HEKLMFOH_00812 2.85e-209 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
HEKLMFOH_00813 2.18e-211 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
HEKLMFOH_00814 1.4e-105 - - - - - - - -
HEKLMFOH_00815 9.71e-274 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HEKLMFOH_00816 2.94e-196 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HEKLMFOH_00817 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
HEKLMFOH_00818 7.01e-244 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HEKLMFOH_00819 1.29e-261 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
HEKLMFOH_00820 2.91e-230 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
HEKLMFOH_00821 1.74e-222 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
HEKLMFOH_00822 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
HEKLMFOH_00823 1.53e-113 ypmB - - S - - - Protein conserved in bacteria
HEKLMFOH_00824 1.13e-271 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HEKLMFOH_00825 1.33e-159 dnaD - - L ko:K02086 - ko00000 Replication initiation and membrane attachment
HEKLMFOH_00826 1.57e-118 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
HEKLMFOH_00827 2.29e-81 - - - P - - - Rhodanese Homology Domain
HEKLMFOH_00828 1.94e-89 - - - S - - - Domain of unknown function (DUF4430)
HEKLMFOH_00829 1.43e-229 - - - U - - - FFAT motif binding
HEKLMFOH_00830 8.08e-147 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF-type riboflavin transporter, S component
HEKLMFOH_00831 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HEKLMFOH_00832 3.16e-204 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type cobalt transport system permease component CbiQ and related transporters
HEKLMFOH_00833 7.84e-92 - - - - - - - -
HEKLMFOH_00834 1.87e-126 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HEKLMFOH_00835 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HEKLMFOH_00836 9.15e-207 - - - K - - - LysR substrate binding domain
HEKLMFOH_00837 1.58e-91 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
HEKLMFOH_00838 0.0 epsA - - I - - - PAP2 superfamily
HEKLMFOH_00839 5.98e-72 - - - S - - - Domain of unknown function (DU1801)
HEKLMFOH_00840 8.65e-144 aqpZ - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HEKLMFOH_00841 1.35e-141 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HEKLMFOH_00842 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
HEKLMFOH_00843 1.02e-125 - - - K - - - Transcriptional regulator, MarR family
HEKLMFOH_00844 7.05e-158 - - - S ko:K07090 - ko00000 membrane transporter protein
HEKLMFOH_00845 2.2e-145 - - - T - - - Tyrosine phosphatase family
HEKLMFOH_00846 4.33e-159 - - - - - - - -
HEKLMFOH_00847 2.38e-160 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HEKLMFOH_00848 2.63e-82 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
HEKLMFOH_00849 7.14e-229 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
HEKLMFOH_00850 1.9e-109 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
HEKLMFOH_00851 1.12e-165 - - - S - - - haloacid dehalogenase-like hydrolase
HEKLMFOH_00852 8.29e-273 - - - EGP ko:K02030,ko:K07552 - ko00000,ko00002,ko02000 Drug resistance transporter Bcr CflA subfamily
HEKLMFOH_00853 3.03e-188 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HEKLMFOH_00854 7.26e-202 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
HEKLMFOH_00855 2.96e-147 - - - - - - - -
HEKLMFOH_00857 5.65e-171 - - - S - - - KR domain
HEKLMFOH_00858 1.8e-87 - - - K - - - HxlR-like helix-turn-helix
HEKLMFOH_00859 5.5e-83 asp2 - - S - - - Asp23 family, cell envelope-related function
HEKLMFOH_00860 4.16e-93 - - - S - - - Asp23 family, cell envelope-related function
HEKLMFOH_00861 1.02e-34 - - - - - - - -
HEKLMFOH_00862 1.23e-119 - - - - - - - -
HEKLMFOH_00863 4.26e-45 - - - S - - - Transglycosylase associated protein
HEKLMFOH_00864 5.64e-202 - - - - - - - -
HEKLMFOH_00865 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
HEKLMFOH_00866 8.84e-171 - - - U - - - Major Facilitator Superfamily
HEKLMFOH_00867 5.1e-45 chaT1 - - U ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
HEKLMFOH_00868 6.28e-124 laaE - - K - - - Transcriptional regulator PadR-like family
HEKLMFOH_00869 3.35e-87 lysM - - M - - - LysM domain
HEKLMFOH_00870 7.47e-174 XK27_07210 - - S - - - B3 4 domain
HEKLMFOH_00871 9.05e-160 - - - K ko:K10914,ko:K21828 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 Cyclic nucleotide-monophosphate binding domain
HEKLMFOH_00872 4.23e-218 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
HEKLMFOH_00873 1e-271 arcT - - E - - - Aminotransferase
HEKLMFOH_00874 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
HEKLMFOH_00875 2.48e-252 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HEKLMFOH_00876 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEKLMFOH_00877 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEKLMFOH_00878 3.58e-155 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
HEKLMFOH_00879 1.02e-176 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
HEKLMFOH_00880 3.01e-58 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
HEKLMFOH_00881 4.53e-238 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEKLMFOH_00882 9.81e-175 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
HEKLMFOH_00883 9.38e-187 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HEKLMFOH_00884 2.79e-197 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HEKLMFOH_00885 2.12e-165 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HEKLMFOH_00886 2.83e-111 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HEKLMFOH_00887 3.42e-97 - - - - - - - -
HEKLMFOH_00888 6.92e-191 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HEKLMFOH_00889 6.8e-178 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HEKLMFOH_00890 8.39e-297 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HEKLMFOH_00891 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HEKLMFOH_00892 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEKLMFOH_00893 4.41e-52 - - - - - - - -
HEKLMFOH_00894 3.03e-106 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HEKLMFOH_00895 2.34e-252 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HEKLMFOH_00896 2.64e-63 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
HEKLMFOH_00897 4.88e-60 ylxQ - - J - - - ribosomal protein
HEKLMFOH_00898 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HEKLMFOH_00899 1.77e-74 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HEKLMFOH_00900 2.19e-219 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HEKLMFOH_00901 1.02e-230 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HEKLMFOH_00902 8.18e-243 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HEKLMFOH_00903 6.17e-124 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HEKLMFOH_00904 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HEKLMFOH_00905 2e-248 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HEKLMFOH_00906 8.25e-25 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
HEKLMFOH_00907 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEKLMFOH_00908 8.72e-301 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
HEKLMFOH_00909 1.02e-46 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEKLMFOH_00910 0.0 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HEKLMFOH_00911 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HEKLMFOH_00912 2.22e-296 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
HEKLMFOH_00913 7.84e-101 - - - T - - - Universal stress protein family
HEKLMFOH_00915 2.15e-298 yfmL - - L - - - DEAD DEAH box helicase
HEKLMFOH_00916 4.05e-242 mocA - - S - - - Oxidoreductase
HEKLMFOH_00917 2.89e-84 - - - S - - - Domain of unknown function (DUF4828)
HEKLMFOH_00918 5.71e-190 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HEKLMFOH_00919 8.34e-195 gntR - - K - - - rpiR family
HEKLMFOH_00920 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HEKLMFOH_00921 4.42e-292 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
HEKLMFOH_00922 1.21e-303 - - - E ko:K03294 - ko00000 amino acid
HEKLMFOH_00923 0.0 fucP - - G ko:K02429 - ko00000,ko02000 Major Facilitator Superfamily
HEKLMFOH_00924 5.83e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HEKLMFOH_00925 0.0 gshA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
HEKLMFOH_00926 1.09e-307 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
HEKLMFOH_00927 6.79e-222 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
HEKLMFOH_00928 1.23e-166 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
HEKLMFOH_00929 2.68e-296 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
HEKLMFOH_00930 1.05e-155 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HEKLMFOH_00931 1.27e-50 - - - K - - - Helix-turn-helix XRE-family like proteins
HEKLMFOH_00932 1.06e-76 - - - K - - - Helix-turn-helix XRE-family like proteins
HEKLMFOH_00933 1.69e-186 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Pfam:Y_phosphatase3C
HEKLMFOH_00934 1.87e-248 namA - - C - - - Oxidoreductase
HEKLMFOH_00935 1.47e-72 - - - E ko:K04031 - ko00000 BMC
HEKLMFOH_00936 1.64e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HEKLMFOH_00937 1.31e-269 pduQ - - C ko:K13921 ko00640,map00640 ko00000,ko00001 Iron-containing alcohol dehydrogenase
HEKLMFOH_00938 0.0 pduP 1.2.1.87 - C ko:K13922 ko00640,map00640 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
HEKLMFOH_00939 7.1e-106 pduO - - S - - - Haem-degrading
HEKLMFOH_00940 7.33e-135 - - - S - - - Cobalamin adenosyltransferase
HEKLMFOH_00941 3.12e-56 pduN - - CQ ko:K04028 - ko00000 Ethanolamine utilisation protein EutN/carboxysome
HEKLMFOH_00942 1.57e-118 - - - S - - - Putative propanediol utilisation
HEKLMFOH_00943 4.18e-147 pduL 2.3.1.222 - Q ko:K13923 ko00640,map00640 ko00000,ko00001,ko01000 Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
HEKLMFOH_00944 3.38e-56 pduJ - - CQ - - - BMC
HEKLMFOH_00945 1.43e-111 - - - CQ - - - BMC
HEKLMFOH_00946 4.67e-75 pduH - - S - - - Dehydratase medium subunit
HEKLMFOH_00947 0.0 pduG - - D - - - Diol dehydratase reactivase ATPase-like domain
HEKLMFOH_00948 7.77e-120 pduE 4.2.1.28 - Q ko:K13920 ko00640,map00640 ko00000,ko00001,ko01000 Dehydratase small subunit
HEKLMFOH_00949 2.39e-166 pduD 4.2.1.28 - Q ko:K13919 ko00640,map00640 ko00000,ko00001,ko01000 Dehydratase medium subunit
HEKLMFOH_00950 0.0 pduC 4.2.1.28 - Q ko:K01699 ko00640,map00640 ko00000,ko00001,ko01000 Dehydratase large subunit
HEKLMFOH_00951 6.34e-166 pduB - - E - - - BMC
HEKLMFOH_00952 1.47e-55 - - - CQ - - - BMC
HEKLMFOH_00953 1.71e-264 - - - K - - - helix_turn_helix, arabinose operon control protein
HEKLMFOH_00954 5.18e-43 - - - S - - - Phage gp6-like head-tail connector protein
HEKLMFOH_00955 0.0 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
HEKLMFOH_00956 6.47e-246 - - - S - - - Phage portal protein
HEKLMFOH_00958 0.0 terL - - S - - - overlaps another CDS with the same product name
HEKLMFOH_00959 2.2e-99 - - - L - - - overlaps another CDS with the same product name
HEKLMFOH_00960 3.64e-66 - - - L - - - HNH endonuclease
HEKLMFOH_00963 8.51e-74 - - - - - - - -
HEKLMFOH_00964 1.91e-299 - - - S - - - Virulence-associated protein E
HEKLMFOH_00965 2.01e-130 - - - L - - - DNA replication protein
HEKLMFOH_00970 4.67e-260 - - - L - - - Belongs to the 'phage' integrase family
HEKLMFOH_00973 2.28e-127 - - - S - - - Protein of unknown function (DUF1211)
HEKLMFOH_00974 1.55e-105 tspO - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 TspO/MBR family
HEKLMFOH_00975 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
HEKLMFOH_00976 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HEKLMFOH_00977 1.06e-198 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
HEKLMFOH_00978 1.32e-269 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 S-adenosylmethionine-dependent methyltransferase
HEKLMFOH_00979 0.0 yclK - - T - - - Histidine kinase
HEKLMFOH_00980 1.15e-189 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
HEKLMFOH_00984 2.89e-198 - - - S - - - Virulence-associated protein E
HEKLMFOH_00985 3.86e-83 - - - L - - - Primase C terminal 1 (PriCT-1)
HEKLMFOH_00990 6.44e-71 - - - S - - - Phage regulatory protein Rha (Phage_pRha)
HEKLMFOH_00993 2.01e-160 sip - - L - - - Belongs to the 'phage' integrase family
HEKLMFOH_00995 1.31e-56 - - - - - - - -
HEKLMFOH_00996 7.48e-159 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
HEKLMFOH_00997 2.84e-104 argO - - S ko:K06895 - ko00000,ko02000 LysE type translocator
HEKLMFOH_00998 8.5e-45 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HEKLMFOH_00999 4.15e-183 - - - I ko:K01066 - ko00000,ko01000 Esterase
HEKLMFOH_01000 7.73e-230 draG - - O - - - ADP-ribosylglycohydrolase
HEKLMFOH_01001 6.17e-133 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HEKLMFOH_01003 2.45e-128 cadD - - P - - - Cadmium resistance transporter
HEKLMFOH_01004 3.26e-101 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HEKLMFOH_01005 1.19e-107 - - - S - - - GtrA-like protein
HEKLMFOH_01006 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HEKLMFOH_01007 9.1e-148 - - - K - - - Bacterial regulatory proteins, tetR family
HEKLMFOH_01008 2.48e-293 - - - S ko:K01421 - ko00000 ABC-2 family transporter protein
HEKLMFOH_01009 8.55e-186 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
HEKLMFOH_01010 4.14e-72 - - - S - - - protein encoded in hypervariable junctions of pilus gene clusters
HEKLMFOH_01011 2.7e-175 - - - - - - - -
HEKLMFOH_01012 5.82e-128 - - - S ko:K09962 - ko00000 Nucleotidyltransferase
HEKLMFOH_01013 1.71e-110 - - - S - - - Protein of unknown function (DUF2798)
HEKLMFOH_01014 2.19e-75 yuxO - - Q - - - Thioesterase superfamily
HEKLMFOH_01015 6.68e-199 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HEKLMFOH_01016 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HEKLMFOH_01017 1.44e-122 - - - S - - - Protein of unknown function (DUF1097)
HEKLMFOH_01018 3.72e-212 - - - - - - - -
HEKLMFOH_01019 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HEKLMFOH_01020 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HEKLMFOH_01021 1.95e-272 - - - E - - - Major Facilitator Superfamily
HEKLMFOH_01024 2.68e-129 - - - K - - - Bacterial regulatory proteins, tetR family
HEKLMFOH_01025 1.02e-231 - - - C - - - nadph quinone reductase
HEKLMFOH_01026 5.55e-137 - - - K - - - Bacterial regulatory proteins, tetR family
HEKLMFOH_01027 2.04e-260 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
HEKLMFOH_01028 6.36e-75 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
HEKLMFOH_01029 0.0 - 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
HEKLMFOH_01030 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HEKLMFOH_01032 4.78e-219 - - - - - - - -
HEKLMFOH_01035 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HEKLMFOH_01036 3.96e-49 ykuJ - - S - - - Protein of unknown function (DUF1797)
HEKLMFOH_01037 6.38e-235 mprF - - S ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HEKLMFOH_01038 7.33e-248 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HEKLMFOH_01039 2e-285 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HEKLMFOH_01040 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HEKLMFOH_01041 2.6e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
HEKLMFOH_01042 3.61e-42 - - - - - - - -
HEKLMFOH_01043 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
HEKLMFOH_01044 1.12e-272 - - - G - - - MucBP domain
HEKLMFOH_01045 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
HEKLMFOH_01046 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HEKLMFOH_01047 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
HEKLMFOH_01048 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
HEKLMFOH_01049 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HEKLMFOH_01050 3.64e-117 - - - - - - - -
HEKLMFOH_01051 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycerophosphotransferase
HEKLMFOH_01052 2.14e-201 - - - - - - - -
HEKLMFOH_01053 2.51e-98 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
HEKLMFOH_01054 6.54e-253 yueF - - S - - - AI-2E family transporter
HEKLMFOH_01055 1.5e-140 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
HEKLMFOH_01056 2.15e-52 - - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
HEKLMFOH_01057 1.51e-280 pbpX2 - - V - - - Beta-lactamase
HEKLMFOH_01058 8.69e-187 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
HEKLMFOH_01059 2.17e-102 ykuP - - C ko:K03839 - ko00000 Flavodoxin
HEKLMFOH_01060 1.56e-203 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
HEKLMFOH_01061 1.3e-201 - - - S - - - Nuclease-related domain
HEKLMFOH_01062 1.05e-272 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HEKLMFOH_01063 1.87e-203 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyltransferase like family 2
HEKLMFOH_01064 5.66e-188 - - - K - - - helix_turn_helix, mercury resistance
HEKLMFOH_01065 3.15e-229 - - - C - - - Zinc-binding dehydrogenase
HEKLMFOH_01066 8.77e-193 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
HEKLMFOH_01067 4.15e-170 - - - Q - - - Methyltransferase domain
HEKLMFOH_01068 0.0 - - - - - - - -
HEKLMFOH_01069 1.9e-257 xerS - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
HEKLMFOH_01070 1.6e-98 rppH3 - - F - - - NUDIX domain
HEKLMFOH_01071 9.09e-129 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HEKLMFOH_01072 1e-106 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
HEKLMFOH_01073 8.23e-132 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
HEKLMFOH_01074 1.94e-216 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
HEKLMFOH_01075 1.06e-235 - - - K - - - Transcriptional regulator
HEKLMFOH_01076 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEKLMFOH_01077 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEKLMFOH_01078 5.45e-138 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HEKLMFOH_01079 1.04e-215 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HEKLMFOH_01080 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HEKLMFOH_01081 1.68e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HEKLMFOH_01082 5.87e-228 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
HEKLMFOH_01083 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEKLMFOH_01084 4.76e-215 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
HEKLMFOH_01085 1.45e-174 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEKLMFOH_01086 1.4e-202 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HEKLMFOH_01088 9.5e-98 abiGI - - K - - - Psort location Cytoplasmic, score
HEKLMFOH_01091 7.45e-166 - - - - - - - -
HEKLMFOH_01092 6.56e-48 yozE - - S - - - Belongs to the UPF0346 family
HEKLMFOH_01093 9.91e-137 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
HEKLMFOH_01094 1.21e-213 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
HEKLMFOH_01095 1.23e-190 WQ51_01275 - - S - - - EDD domain protein, DegV family
HEKLMFOH_01096 1.06e-147 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
HEKLMFOH_01097 0.0 - - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 ABC transporter
HEKLMFOH_01100 0.0 - - - - - - - -
HEKLMFOH_01101 1.18e-50 - - - - - - - -
HEKLMFOH_01102 0.0 - - - E - - - Peptidase family C69
HEKLMFOH_01103 4.42e-154 rcfA - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
HEKLMFOH_01104 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HEKLMFOH_01105 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
HEKLMFOH_01106 3.16e-170 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HEKLMFOH_01107 4.57e-71 - - - S - - - Protein of unknown function (DUF1516)
HEKLMFOH_01108 2.14e-127 ywjB - - H - - - RibD C-terminal domain
HEKLMFOH_01109 1.53e-305 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
HEKLMFOH_01110 3.49e-24 - - - - - - - -
HEKLMFOH_01112 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HEKLMFOH_01113 5.9e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HEKLMFOH_01114 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HEKLMFOH_01115 1.93e-68 yheA - - S - - - Belongs to the UPF0342 family
HEKLMFOH_01116 4.27e-293 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
HEKLMFOH_01117 0.0 yhaN - - L - - - AAA domain
HEKLMFOH_01118 8.11e-237 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
HEKLMFOH_01119 8.85e-195 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HEKLMFOH_01120 1.78e-67 - - - - - - - -
HEKLMFOH_01121 5.29e-109 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
HEKLMFOH_01122 2.85e-173 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEKLMFOH_01123 5.74e-284 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HEKLMFOH_01124 2.23e-192 ytmP - - M - - - Choline/ethanolamine kinase
HEKLMFOH_01125 7.82e-160 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HEKLMFOH_01126 4.82e-164 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HEKLMFOH_01127 3.37e-56 eutP - - E ko:K04029 - ko00000 Ethanolamine utilisation - propanediol utilisation
HEKLMFOH_01128 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEKLMFOH_01129 6.69e-239 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
HEKLMFOH_01130 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEKLMFOH_01131 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HEKLMFOH_01132 4.8e-66 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEKLMFOH_01133 1.33e-257 camS - - S - - - sex pheromone
HEKLMFOH_01134 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HEKLMFOH_01135 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HEKLMFOH_01136 1.74e-274 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HEKLMFOH_01137 2.26e-129 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HEKLMFOH_01138 3.87e-208 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
HEKLMFOH_01139 6.63e-232 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HEKLMFOH_01140 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HEKLMFOH_01141 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HEKLMFOH_01142 6.5e-224 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
HEKLMFOH_01143 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
HEKLMFOH_01144 1.39e-228 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HEKLMFOH_01145 4.22e-182 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HEKLMFOH_01146 1.29e-210 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HEKLMFOH_01147 3.55e-198 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HEKLMFOH_01148 3.3e-79 - - - S - - - SPTR Capsular exopolysaccharide biosynthesis protein (Wzm)
HEKLMFOH_01149 2.9e-101 cps2J - - S - - - Polysaccharide biosynthesis protein
HEKLMFOH_01150 1.67e-20 - - - - - - - -
HEKLMFOH_01153 3.2e-70 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HEKLMFOH_01154 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
HEKLMFOH_01155 1.64e-196 - - - S - - - Calcineurin-like phosphoesterase
HEKLMFOH_01158 1.08e-176 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEKLMFOH_01159 2.69e-277 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
HEKLMFOH_01160 1.28e-161 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
HEKLMFOH_01161 7.88e-121 yfbM - - K - - - FR47-like protein
HEKLMFOH_01162 1.34e-180 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HEKLMFOH_01163 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HEKLMFOH_01164 9.45e-196 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HEKLMFOH_01165 3.12e-95 - - - - ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 -
HEKLMFOH_01166 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
HEKLMFOH_01167 1.75e-115 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
HEKLMFOH_01168 2.07e-203 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HEKLMFOH_01170 4.34e-63 - 4.1.1.52, 4.2.1.83 - E ko:K07045,ko:K10220,ko:K22213 ko00362,ko01120,map00362,map01120 ko00000,ko00001,ko01000 amidohydrolase
HEKLMFOH_01172 9.17e-131 - - - S - - - Psort location CytoplasmicMembrane, score
HEKLMFOH_01173 6.05e-98 - - - K - - - MarR family
HEKLMFOH_01174 5.89e-312 dinF - - V - - - MatE
HEKLMFOH_01175 4.36e-142 - - - S - - - HAD hydrolase, family IA, variant
HEKLMFOH_01176 1.31e-71 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HEKLMFOH_01177 1.41e-77 manX 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HEKLMFOH_01178 1.13e-175 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
HEKLMFOH_01179 6.42e-198 manN - - G ko:K02796,ko:K02815 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
HEKLMFOH_01180 1.91e-226 ydbI - - K - - - AI-2E family transporter
HEKLMFOH_01181 7.27e-72 - - - T - - - diguanylate cyclase
HEKLMFOH_01182 8.1e-153 - - - T - - - Putative diguanylate phosphodiesterase
HEKLMFOH_01183 2.02e-131 - - - K - - - Bacterial regulatory proteins, tetR family
HEKLMFOH_01184 0.0 XK27_06930 - - V ko:K01421 - ko00000 domain protein
HEKLMFOH_01185 3.61e-214 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HEKLMFOH_01186 2.72e-261 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HEKLMFOH_01187 5.71e-212 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
HEKLMFOH_01188 5.41e-231 - - - EG - - - EamA-like transporter family
HEKLMFOH_01189 8.39e-159 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HEKLMFOH_01190 2.38e-293 - - - V - - - Beta-lactamase
HEKLMFOH_01191 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HEKLMFOH_01193 1.63e-163 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HEKLMFOH_01194 1.42e-74 - - - - - - - -
HEKLMFOH_01195 2.6e-129 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
HEKLMFOH_01196 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HEKLMFOH_01197 2.11e-272 yacL - - S - - - domain protein
HEKLMFOH_01198 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HEKLMFOH_01199 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HEKLMFOH_01200 7.28e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HEKLMFOH_01201 5.21e-178 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEKLMFOH_01202 1.04e-116 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
HEKLMFOH_01203 1.37e-129 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Sigma-70 region 2
HEKLMFOH_01204 1.27e-34 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HEKLMFOH_01205 1.61e-127 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HEKLMFOH_01206 4.14e-94 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HEKLMFOH_01207 1.75e-160 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HEKLMFOH_01208 1.3e-110 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HEKLMFOH_01209 7.9e-74 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HEKLMFOH_01210 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HEKLMFOH_01211 7.64e-142 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HEKLMFOH_01212 1.17e-219 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
HEKLMFOH_01213 4.42e-249 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEKLMFOH_01214 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEKLMFOH_01215 9.51e-51 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
HEKLMFOH_01216 1.36e-145 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
HEKLMFOH_01217 2.2e-123 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HEKLMFOH_01218 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEKLMFOH_01219 6.48e-56 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HEKLMFOH_01220 2.17e-140 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HEKLMFOH_01221 2.48e-52 yaaL - - S - - - Protein of unknown function (DUF2508)
HEKLMFOH_01222 2.72e-145 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HEKLMFOH_01223 1.44e-72 yaaQ - - S - - - Cyclic-di-AMP receptor
HEKLMFOH_01224 9.74e-231 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HEKLMFOH_01225 3.21e-62 yabA - - L - - - Involved in initiation control of chromosome replication
HEKLMFOH_01226 4.05e-210 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HEKLMFOH_01227 9.84e-183 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
HEKLMFOH_01228 1.01e-163 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
HEKLMFOH_01229 4.04e-142 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
HEKLMFOH_01230 1.74e-250 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HEKLMFOH_01231 6.59e-275 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
HEKLMFOH_01232 8.86e-62 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HEKLMFOH_01233 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
HEKLMFOH_01234 5.69e-147 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HEKLMFOH_01235 1.56e-60 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HEKLMFOH_01236 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HEKLMFOH_01237 0.0 ydaO - - E - - - amino acid
HEKLMFOH_01238 1.8e-180 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
HEKLMFOH_01239 6.75e-91 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
HEKLMFOH_01240 6.19e-243 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
HEKLMFOH_01241 1.75e-149 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
HEKLMFOH_01242 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
HEKLMFOH_01243 8.73e-164 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
HEKLMFOH_01244 3.5e-126 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HEKLMFOH_01245 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HEKLMFOH_01246 2.19e-234 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HEKLMFOH_01247 1.2e-282 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
HEKLMFOH_01248 1.44e-165 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HEKLMFOH_01249 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEKLMFOH_01250 2.25e-207 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HEKLMFOH_01251 5.41e-202 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HEKLMFOH_01252 1.68e-198 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
HEKLMFOH_01253 5.24e-192 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEKLMFOH_01254 6.12e-180 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEKLMFOH_01255 1.68e-155 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
HEKLMFOH_01256 5.88e-72 - - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
HEKLMFOH_01257 7.21e-50 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
HEKLMFOH_01258 4.08e-219 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HEKLMFOH_01259 2.41e-199 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HEKLMFOH_01260 2.14e-234 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HEKLMFOH_01261 1.73e-215 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HEKLMFOH_01262 3.26e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HEKLMFOH_01264 3.17e-149 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
HEKLMFOH_01265 1.06e-121 - - - K - - - acetyltransferase
HEKLMFOH_01266 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HEKLMFOH_01267 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HEKLMFOH_01268 2.03e-118 - - - S - - - Short repeat of unknown function (DUF308)
HEKLMFOH_01269 5.33e-211 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HEKLMFOH_01270 3.47e-244 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
HEKLMFOH_01271 4.23e-217 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HEKLMFOH_01272 2.08e-133 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HEKLMFOH_01273 3.75e-98 - - - K - - - LytTr DNA-binding domain
HEKLMFOH_01274 1.88e-162 - - - S - - - membrane
HEKLMFOH_01276 3.44e-139 - - - S - - - ECF transporter, substrate-specific component
HEKLMFOH_01278 8.45e-239 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
HEKLMFOH_01279 8.53e-245 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HEKLMFOH_01280 7.88e-287 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
HEKLMFOH_01281 5.46e-179 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HEKLMFOH_01282 1.89e-316 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HEKLMFOH_01284 0.0 eriC - - P ko:K03281 - ko00000 chloride
HEKLMFOH_01285 1.06e-44 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HEKLMFOH_01286 3.69e-181 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
HEKLMFOH_01287 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HEKLMFOH_01288 4.3e-106 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HEKLMFOH_01289 1.18e-169 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HEKLMFOH_01290 2.15e-153 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HEKLMFOH_01291 6.48e-120 - - - V - - - VanZ like family
HEKLMFOH_01292 4.9e-111 ysaA - - V - - - VanZ like family
HEKLMFOH_01293 1e-96 gtcA - - S - - - Teichoic acid glycosylation protein
HEKLMFOH_01294 1.61e-113 - - - S - - - ECF transporter, substrate-specific component
HEKLMFOH_01295 2.42e-204 - - - S - - - EDD domain protein, DegV family
HEKLMFOH_01296 1.28e-295 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
HEKLMFOH_01297 2.2e-252 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
HEKLMFOH_01298 2.12e-92 - - - K - - - Transcriptional regulator
HEKLMFOH_01299 0.0 FbpA - - K - - - Fibronectin-binding protein
HEKLMFOH_01300 0.0 pyrAB2 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HEKLMFOH_01301 8.1e-261 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
HEKLMFOH_01302 6.85e-115 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HEKLMFOH_01303 3.64e-220 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HEKLMFOH_01304 7.74e-106 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HEKLMFOH_01305 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
HEKLMFOH_01306 1.53e-74 esbA - - S - - - Family of unknown function (DUF5322)
HEKLMFOH_01307 1.59e-90 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
HEKLMFOH_01308 7.55e-265 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 FAD dependent oxidoreductase
HEKLMFOH_01309 1.79e-144 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
HEKLMFOH_01310 1.5e-112 - - - K - - - Bacterial regulatory proteins, tetR family
HEKLMFOH_01311 2.93e-159 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HEKLMFOH_01312 7.85e-71 - - - - - - - -
HEKLMFOH_01313 2.96e-109 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
HEKLMFOH_01314 1.17e-38 - - - - - - - -
HEKLMFOH_01315 6.68e-315 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
HEKLMFOH_01316 6.93e-88 - - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
HEKLMFOH_01317 2.4e-280 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HEKLMFOH_01319 7e-52 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HEKLMFOH_01320 1.96e-138 ypsA - - S - - - Belongs to the UPF0398 family
HEKLMFOH_01321 9.96e-147 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HEKLMFOH_01322 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
HEKLMFOH_01324 6.41e-224 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
HEKLMFOH_01325 2.56e-119 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
HEKLMFOH_01326 4.21e-146 - - - S - - - VIT family
HEKLMFOH_01327 1.07e-151 - - - S - - - membrane
HEKLMFOH_01328 0.0 ybeC - - E - - - amino acid
HEKLMFOH_01329 8.53e-104 yoaA - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HEKLMFOH_01330 2.38e-252 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
HEKLMFOH_01331 2.04e-225 - - - - - - - -
HEKLMFOH_01332 1.82e-161 - - - - - - - -
HEKLMFOH_01333 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
HEKLMFOH_01334 5.26e-58 - - - - - - - -
HEKLMFOH_01335 1.35e-42 - - - - - - - -
HEKLMFOH_01336 2.61e-76 - - - - - - - -
HEKLMFOH_01337 3.04e-202 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HEKLMFOH_01338 4.2e-215 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HEKLMFOH_01339 3.48e-192 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
HEKLMFOH_01340 2.06e-190 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEKLMFOH_01341 1.77e-263 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEKLMFOH_01342 1.47e-174 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HEKLMFOH_01343 9.72e-188 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HEKLMFOH_01344 4.94e-268 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HEKLMFOH_01348 2.4e-53 - - - K - - - Acetyltransferase (GNAT) domain
HEKLMFOH_01349 2.04e-227 - - - U ko:K07241 - ko00000,ko02000 High-affinity nickel-transport protein
HEKLMFOH_01350 4.21e-60 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HEKLMFOH_01351 9.9e-49 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HEKLMFOH_01352 8.69e-193 larE - - S ko:K06864 - ko00000 NAD synthase
HEKLMFOH_01353 2.38e-293 larC 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HEKLMFOH_01354 3.94e-172 larB - - S ko:K06898 - ko00000 AIR carboxylase
HEKLMFOH_01355 9.47e-299 larA 5.1.2.1 - S ko:K22373 ko00620,map00620 ko00000,ko00001,ko01000 Domain of unknown function (DUF2088)
HEKLMFOH_01356 7.83e-20 rcfB - - K - - - Crp-like helix-turn-helix domain
HEKLMFOH_01357 5.87e-298 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
HEKLMFOH_01358 3.62e-121 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
HEKLMFOH_01359 5.25e-178 yhfI - - S - - - Metallo-beta-lactamase superfamily
HEKLMFOH_01360 3.6e-92 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HEKLMFOH_01361 7.66e-166 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HEKLMFOH_01362 4.44e-131 - - - T - - - EAL domain
HEKLMFOH_01363 6.72e-118 - - - - - - - -
HEKLMFOH_01364 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
HEKLMFOH_01366 9.68e-134 ytqB - - J - - - Putative rRNA methylase
HEKLMFOH_01367 6.66e-151 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
HEKLMFOH_01368 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HEKLMFOH_01369 1.19e-154 - - - P ko:K01990 - ko00000,ko00002,ko02000 ABC-type multidrug transport system ATPase component
HEKLMFOH_01370 8.42e-188 - - - S - - - NADPH-dependent FMN reductase
HEKLMFOH_01371 2.16e-68 - - - - - - - -
HEKLMFOH_01372 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HEKLMFOH_01373 1.69e-161 - 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 pseudouridine synthase activity
HEKLMFOH_01374 1.89e-191 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HEKLMFOH_01375 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
HEKLMFOH_01376 1.85e-110 - - - T - - - Belongs to the universal stress protein A family
HEKLMFOH_01377 3.86e-260 ald 1.4.1.1 - C ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
HEKLMFOH_01378 2.4e-312 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HEKLMFOH_01379 3.29e-73 - - - S - - - Small secreted protein
HEKLMFOH_01380 2.29e-74 ytpP - - CO - - - Thioredoxin
HEKLMFOH_01381 1.63e-146 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEKLMFOH_01382 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HEKLMFOH_01383 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HEKLMFOH_01384 1.13e-273 yttB - - EGP - - - Major Facilitator
HEKLMFOH_01385 5.04e-312 glpT - - G ko:K02445 - ko00000,ko02000 Major Facilitator Superfamily
HEKLMFOH_01386 1.38e-174 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
HEKLMFOH_01387 1.14e-110 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
HEKLMFOH_01388 0.0 - - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
HEKLMFOH_01389 0.0 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
HEKLMFOH_01391 3.41e-184 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEKLMFOH_01392 5.17e-223 - - - K ko:K02525 - ko00000,ko03000 Transcriptional regulator, LacI family
HEKLMFOH_01393 1.63e-314 yhdP - - S - - - Transporter associated domain
HEKLMFOH_01394 6.61e-80 - - - - - - - -
HEKLMFOH_01395 5.23e-97 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HEKLMFOH_01396 0.0 - - - E - - - Amino Acid
HEKLMFOH_01397 2.74e-207 yvgN - - S - - - Aldo keto reductase
HEKLMFOH_01398 6.97e-05 - - - - - - - -
HEKLMFOH_01399 0.0 yfgQ - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
HEKLMFOH_01400 8.76e-121 - - - K - - - Domain of unknown function (DUF1836)
HEKLMFOH_01401 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
HEKLMFOH_01402 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
HEKLMFOH_01403 3.32e-122 - - - M - - - LysM domain protein
HEKLMFOH_01405 1.4e-209 oroP - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
HEKLMFOH_01406 3.04e-231 iunH5 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 inosine-uridine preferring nucleoside hydrolase
HEKLMFOH_01407 7.27e-42 - - - - - - - -
HEKLMFOH_01408 0.0 - 2.8.2.22 - M ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
HEKLMFOH_01409 4.86e-174 - - - S - - - B3/4 domain
HEKLMFOH_01410 2.29e-164 - - - S - - - Protein of unknown function (DUF975)
HEKLMFOH_01411 2.63e-82 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
HEKLMFOH_01412 6.18e-207 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEKLMFOH_01413 1.23e-225 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
HEKLMFOH_01414 5.8e-248 - - - KT ko:K02647 - ko00000,ko03000 Putative sugar diacid recognition
HEKLMFOH_01415 5.73e-272 yojA - - EG ko:K03299 - ko00000,ko02000 GntP family permease
HEKLMFOH_01416 5.11e-265 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HEKLMFOH_01417 0.0 ydbT - - S ko:K08981 - ko00000 Bacterial PH domain
HEKLMFOH_01418 1.33e-110 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
HEKLMFOH_01419 1.73e-102 - 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside 2-deoxyribosyltransferase
HEKLMFOH_01420 0.0 - - - U ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
HEKLMFOH_01421 2.65e-48 - - - - - - - -
HEKLMFOH_01422 0.0 - - - K - - - Mga helix-turn-helix domain
HEKLMFOH_01423 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
HEKLMFOH_01424 1e-76 - - - K - - - Winged helix DNA-binding domain
HEKLMFOH_01425 1.07e-43 - - - - - - - -
HEKLMFOH_01426 5.99e-303 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HEKLMFOH_01427 6.23e-305 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HEKLMFOH_01428 8.6e-223 ywtF_2 - - K - - - Cell envelope-related transcriptional attenuator domain
HEKLMFOH_01429 0.0 norG_2 - - K - - - Aminotransferase class I and II
HEKLMFOH_01430 3.8e-180 thiD 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
HEKLMFOH_01431 5.54e-111 hmpT - - S - - - ECF-type riboflavin transporter, S component
HEKLMFOH_01432 3.12e-129 ywlG - - S - - - Belongs to the UPF0340 family
HEKLMFOH_01433 1.48e-69 - - - S - - - Pentapeptide repeats (8 copies)
HEKLMFOH_01434 7.41e-229 - - - K ko:K02529,ko:K03435 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HEKLMFOH_01436 2.49e-200 rihA - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
HEKLMFOH_01437 3.8e-152 - - - S - - - Protein of unknown function (DUF1275)
HEKLMFOH_01438 0.0 astA 2.8.2.22 - M ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
HEKLMFOH_01439 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HEKLMFOH_01440 0.0 nhaP2 - - P ko:K03316 - ko00000 Sodium proton antiporter
HEKLMFOH_01441 3.64e-86 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HEKLMFOH_01442 7.46e-59 - - - - - - - -
HEKLMFOH_01443 1.42e-218 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEKLMFOH_01444 0.0 - 3.4.19.1 - E ko:K01303 - ko00000,ko01000,ko01002 Prolyl oligopeptidase family
HEKLMFOH_01445 2.2e-79 - - - K - - - Helix-turn-helix domain
HEKLMFOH_01446 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HEKLMFOH_01448 3.46e-268 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HEKLMFOH_01449 1.8e-215 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEKLMFOH_01450 2.36e-315 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
HEKLMFOH_01451 9.57e-36 - - - - - - - -
HEKLMFOH_01452 3.19e-240 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
HEKLMFOH_01453 2.69e-276 - - - - - - - -
HEKLMFOH_01454 3.56e-55 - - - - - - - -
HEKLMFOH_01456 1.59e-10 - - - - - - - -
HEKLMFOH_01457 4.78e-79 - - - - - - - -
HEKLMFOH_01458 3.29e-153 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HEKLMFOH_01459 3.54e-148 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HEKLMFOH_01460 0.0 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HEKLMFOH_01461 1.8e-124 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC transporter permease
HEKLMFOH_01462 7.88e-215 - 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HEKLMFOH_01463 1.02e-278 - 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HEKLMFOH_01464 6.93e-106 cat 2.3.1.28 - V ko:K19271 - br01600,ko00000,ko01000,ko01504 Chloramphenicol acetyltransferase
HEKLMFOH_01465 8.63e-41 cat 2.3.1.28 - V ko:K19271 - br01600,ko00000,ko01000,ko01504 Chloramphenicol acetyltransferase
HEKLMFOH_01466 5.88e-72 - - - S - - - LuxR family transcriptional regulator
HEKLMFOH_01467 2.79e-176 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2087)
HEKLMFOH_01468 7.02e-44 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - S ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 of the HAD superfamily
HEKLMFOH_01469 9.55e-303 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEKLMFOH_01470 1.76e-193 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HEKLMFOH_01471 4.15e-192 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HEKLMFOH_01472 7.94e-126 - - - - - - - -
HEKLMFOH_01473 7.85e-241 pva2 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
HEKLMFOH_01474 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
HEKLMFOH_01475 1.41e-266 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HEKLMFOH_01476 1.43e-134 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
HEKLMFOH_01477 7.1e-188 - - - S - - - Zinc-dependent metalloprotease
HEKLMFOH_01478 9.55e-216 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 hydrolase, family 25
HEKLMFOH_01479 1.78e-263 - - - G - - - Glycosyl hydrolases family 8
HEKLMFOH_01480 1.64e-72 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
HEKLMFOH_01481 9.41e-104 yphH - - S - - - Cupin domain
HEKLMFOH_01482 2.05e-99 - - - K - - - helix_turn_helix, mercury resistance
HEKLMFOH_01483 5.81e-131 yobS - - K - - - Bacterial regulatory proteins, tetR family
HEKLMFOH_01485 3.15e-295 - - - - - - - -
HEKLMFOH_01486 2.52e-202 dkgB - - S - - - reductase
HEKLMFOH_01487 7.38e-257 - - - EGP - - - Major Facilitator
HEKLMFOH_01488 1.91e-263 - - - EGP - - - Major Facilitator
HEKLMFOH_01489 2.18e-164 namA - - C - - - Oxidoreductase
HEKLMFOH_01490 1.51e-53 pduN - - CQ ko:K04028 - ko00000 Ethanolamine utilisation protein EutN/carboxysome
HEKLMFOH_01491 7.79e-71 - - - K - - - helix_turn_helix, arabinose operon control protein
HEKLMFOH_01492 1.06e-312 - 3.4.16.4 - V ko:K01286 - ko00000,ko01000 SH3-like domain
HEKLMFOH_01493 7.21e-143 acmA - - NU - - - mannosyl-glycoprotein
HEKLMFOH_01494 1.15e-234 - - - S - - - DUF218 domain
HEKLMFOH_01495 2.25e-239 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HEKLMFOH_01496 3.94e-172 - 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
HEKLMFOH_01498 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
HEKLMFOH_01499 0.0 ydiC1 - - EGP - - - Major Facilitator
HEKLMFOH_01500 3.27e-118 - - - K - - - Transcriptional regulator PadR-like family
HEKLMFOH_01501 1.69e-107 - - - K - - - MerR family regulatory protein
HEKLMFOH_01502 3.35e-89 lytE - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family
HEKLMFOH_01503 3.26e-101 yyaT - - K ko:K02348 - ko00000 protein acetylation
HEKLMFOH_01504 2.32e-159 pgm3 - - G - - - phosphoglycerate mutase family
HEKLMFOH_01505 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HEKLMFOH_01506 4.49e-233 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
HEKLMFOH_01507 1.7e-186 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HEKLMFOH_01508 2.86e-244 - - - S - - - Protease prsW family
HEKLMFOH_01509 6.11e-229 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
HEKLMFOH_01510 6.95e-10 - - - - - - - -
HEKLMFOH_01511 1.69e-184 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
HEKLMFOH_01512 7.66e-308 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HEKLMFOH_01513 2.8e-229 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HEKLMFOH_01514 9e-74 - - - S - - - Domain of unknown function (DUF3899)
HEKLMFOH_01515 7.79e-93 - - - K - - - helix_turn_helix, mercury resistance
HEKLMFOH_01516 1.55e-168 gntR - - K - - - UbiC transcription regulator-associated domain protein
HEKLMFOH_01517 0.0 xpkA 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
HEKLMFOH_01518 1.89e-188 yxeH - - S - - - hydrolase
HEKLMFOH_01519 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
HEKLMFOH_01520 1.89e-192 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
HEKLMFOH_01521 1.22e-102 ywiB - - S - - - Domain of unknown function (DUF1934)
HEKLMFOH_01522 3.8e-78 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HEKLMFOH_01523 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HEKLMFOH_01524 2.93e-103 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
HEKLMFOH_01525 1.71e-47 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
HEKLMFOH_01526 4.23e-153 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
HEKLMFOH_01527 3.08e-302 - - - F ko:K03458 - ko00000 Permease
HEKLMFOH_01528 0.0 guaD 3.5.4.3 - F ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Amidohydrolase family
HEKLMFOH_01529 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HEKLMFOH_01530 4.06e-211 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HEKLMFOH_01531 3.57e-144 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HEKLMFOH_01532 4.94e-114 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HEKLMFOH_01533 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
HEKLMFOH_01534 3.47e-214 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
HEKLMFOH_01535 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HEKLMFOH_01536 2.31e-101 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HEKLMFOH_01537 2.41e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HEKLMFOH_01538 6.09e-72 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HEKLMFOH_01539 2.6e-134 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
HEKLMFOH_01540 1.3e-284 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
HEKLMFOH_01541 2.58e-65 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
HEKLMFOH_01542 1.58e-152 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HEKLMFOH_01543 2.75e-142 yqeK - - H - - - Hydrolase, HD family
HEKLMFOH_01544 2.59e-77 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HEKLMFOH_01545 3.56e-181 yqeM - - Q - - - Methyltransferase
HEKLMFOH_01546 1.74e-274 ylbM - - S - - - Belongs to the UPF0348 family
HEKLMFOH_01547 4.1e-124 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
HEKLMFOH_01548 4.39e-39 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
HEKLMFOH_01549 2.14e-189 - 3.1.3.23 - S ko:K07757 - ko00000,ko01000 Sucrose-6F-phosphate phosphohydrolase
HEKLMFOH_01550 1.08e-67 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
HEKLMFOH_01551 8.69e-149 - - - O - - - Zinc-dependent metalloprotease
HEKLMFOH_01552 4.42e-248 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HEKLMFOH_01553 3.25e-154 csrR - - K - - - response regulator
HEKLMFOH_01554 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEKLMFOH_01555 2.35e-92 yxeA - - S - - - Protein of unknown function (DUF1093)
HEKLMFOH_01556 1e-181 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEKLMFOH_01557 3.93e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
HEKLMFOH_01558 5.03e-181 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEKLMFOH_01559 8.56e-119 - - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HEKLMFOH_01560 1.03e-88 yodB - - K - - - Transcriptional regulator, HxlR family
HEKLMFOH_01561 1.45e-258 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HEKLMFOH_01562 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEKLMFOH_01563 3.09e-266 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HEKLMFOH_01564 5.67e-155 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
HEKLMFOH_01565 6.68e-93 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HEKLMFOH_01566 8.94e-75 yneR - - S - - - Belongs to the HesB IscA family
HEKLMFOH_01567 0.0 - - - S - - - membrane
HEKLMFOH_01568 5.88e-38 - - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
HEKLMFOH_01569 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HEKLMFOH_01570 5.33e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HEKLMFOH_01571 2.21e-127 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HEKLMFOH_01572 6.85e-155 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
HEKLMFOH_01573 9.85e-49 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
HEKLMFOH_01574 3.99e-232 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
HEKLMFOH_01575 1.11e-92 yqhL - - P - - - Rhodanese-like protein
HEKLMFOH_01576 1.23e-32 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
HEKLMFOH_01577 2.92e-182 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
HEKLMFOH_01578 4.25e-219 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HEKLMFOH_01579 7.74e-86 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
HEKLMFOH_01580 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HEKLMFOH_01581 1.11e-201 - - - - - - - -
HEKLMFOH_01582 7.15e-230 - - - - - - - -
HEKLMFOH_01583 7.73e-127 - - - S - - - Protein conserved in bacteria
HEKLMFOH_01584 8.42e-124 - - - K - - - Transcriptional regulator
HEKLMFOH_01585 5.22e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HEKLMFOH_01586 7.92e-76 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
HEKLMFOH_01587 8.46e-65 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HEKLMFOH_01588 7.11e-253 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HEKLMFOH_01589 5.18e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HEKLMFOH_01590 5.15e-95 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
HEKLMFOH_01591 2.79e-97 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HEKLMFOH_01592 3.85e-201 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HEKLMFOH_01593 3.16e-312 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEKLMFOH_01594 1.65e-47 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEKLMFOH_01595 3.09e-213 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HEKLMFOH_01596 3.41e-191 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
HEKLMFOH_01597 9.88e-100 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HEKLMFOH_01598 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HEKLMFOH_01600 6.94e-70 - - - - - - - -
HEKLMFOH_01601 2.35e-134 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HEKLMFOH_01602 2.53e-42 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HEKLMFOH_01603 9.37e-276 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HEKLMFOH_01604 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEKLMFOH_01605 1.32e-221 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HEKLMFOH_01606 4.18e-315 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HEKLMFOH_01607 8.97e-171 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
HEKLMFOH_01608 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HEKLMFOH_01609 4.57e-214 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HEKLMFOH_01610 1.34e-152 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HEKLMFOH_01611 1.77e-165 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
HEKLMFOH_01612 4.64e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HEKLMFOH_01613 1.43e-75 yloU - - S - - - Asp23 family, cell envelope-related function
HEKLMFOH_01614 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
HEKLMFOH_01615 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HEKLMFOH_01616 1.92e-241 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HEKLMFOH_01617 9.76e-50 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEKLMFOH_01618 5.47e-167 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HEKLMFOH_01619 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HEKLMFOH_01620 1.64e-249 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HEKLMFOH_01621 8.53e-76 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HEKLMFOH_01622 1.42e-279 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HEKLMFOH_01623 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HEKLMFOH_01624 1.55e-272 - - - S - - - associated with various cellular activities
HEKLMFOH_01625 0.0 - - - S - - - Putative metallopeptidase domain
HEKLMFOH_01626 7.31e-65 - - - - - - - -
HEKLMFOH_01627 3.48e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HEKLMFOH_01628 6.46e-54 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
HEKLMFOH_01629 8.79e-120 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HEKLMFOH_01630 3.84e-184 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HEKLMFOH_01631 2.13e-76 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HEKLMFOH_01632 2.36e-19 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HEKLMFOH_01633 9.21e-99 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HEKLMFOH_01634 2.5e-104 - - - K - - - Transcriptional regulator
HEKLMFOH_01635 8.08e-234 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HEKLMFOH_01636 1.84e-49 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEKLMFOH_01637 7.29e-214 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
HEKLMFOH_01638 2.74e-157 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
HEKLMFOH_01639 8.3e-293 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HEKLMFOH_01640 5.03e-95 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HEKLMFOH_01641 2e-94 fabZ2 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
HEKLMFOH_01642 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
HEKLMFOH_01643 9.5e-201 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HEKLMFOH_01644 6.89e-183 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
HEKLMFOH_01645 7.68e-174 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
HEKLMFOH_01646 4.85e-187 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HEKLMFOH_01647 6.62e-111 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HEKLMFOH_01648 1.25e-67 - - - S - - - MazG nucleotide pyrophosphohydrolase domain
HEKLMFOH_01649 1.58e-117 entB - - Q - - - Isochorismatase family
HEKLMFOH_01650 4.7e-103 - - - S - - - Protein of unknown function (DUF3021)
HEKLMFOH_01651 2.27e-98 - - - K - - - LytTr DNA-binding domain
HEKLMFOH_01652 6.27e-67 - - - N ko:K18843 - ko00000,ko02048 PFAM Uncharacterised protein family UPF0150
HEKLMFOH_01653 3.6e-118 - - - S - - - DJ-1/PfpI family
HEKLMFOH_01654 5.23e-43 - - - S - - - YjbR
HEKLMFOH_01655 1.67e-225 - - - C - - - Zinc-binding dehydrogenase
HEKLMFOH_01656 3.03e-192 larE - - S ko:K06864 - ko00000 NAD synthase
HEKLMFOH_01657 1.19e-170 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HEKLMFOH_01658 3.01e-97 larC2 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Protein of unknown function DUF111
HEKLMFOH_01659 3.37e-178 larC 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HEKLMFOH_01660 6.12e-157 larB - - S ko:K06898 - ko00000 AIR carboxylase
HEKLMFOH_01661 7.9e-306 larA 5.1.2.1 - S ko:K22373 ko00620,map00620 ko00000,ko00001,ko01000 Domain of unknown function (DUF2088)
HEKLMFOH_01662 2.31e-155 rcfB - - K - - - Crp-like helix-turn-helix domain
HEKLMFOH_01663 1.29e-235 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
HEKLMFOH_01664 1.39e-191 - - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HEKLMFOH_01665 2.48e-165 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEKLMFOH_01666 6.83e-54 - - - - - - - -
HEKLMFOH_01667 1.15e-154 ant1 2.7.7.47 - H ko:K00984 - ko00000,ko01000,ko01504 Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HEKLMFOH_01668 1.91e-81 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HEKLMFOH_01669 1.13e-44 - - - - - - - -
HEKLMFOH_01670 6.69e-07 - - - - - - - -
HEKLMFOH_01671 4.68e-192 - - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
HEKLMFOH_01672 2.07e-46 - - - - - - - -
HEKLMFOH_01674 4.08e-62 - - - - - - - -
HEKLMFOH_01675 7.16e-122 - - - V - - - VanZ like family
HEKLMFOH_01676 2.39e-108 ohrR - - K - - - Transcriptional regulator
HEKLMFOH_01677 1.75e-157 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HEKLMFOH_01678 3.58e-51 - - - - - - - -
HEKLMFOH_01679 9.72e-227 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEKLMFOH_01680 0.0 trePP 2.4.1.216, 2.4.1.8 GH65 G ko:K00691,ko:K03731 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65 central catalytic domain
HEKLMFOH_01681 1.82e-153 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
HEKLMFOH_01682 7.76e-185 - - - S - - - haloacid dehalogenase-like hydrolase
HEKLMFOH_01683 1.03e-155 dgk2 - - F - - - Deoxynucleoside kinase
HEKLMFOH_01684 1.39e-74 XK27_08430 - - S - - - Staphylococcal protein of unknown function (DUF960)
HEKLMFOH_01685 0.0 mdr - - EGP - - - Major Facilitator
HEKLMFOH_01686 3.39e-274 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HEKLMFOH_01687 1.42e-156 - - - - - - - -
HEKLMFOH_01688 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HEKLMFOH_01689 1.22e-36 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
HEKLMFOH_01690 2.96e-198 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HEKLMFOH_01691 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HEKLMFOH_01692 0.0 potE - - E - - - Amino Acid
HEKLMFOH_01693 2.74e-96 - - - K - - - Helix-turn-helix
HEKLMFOH_01694 2.76e-63 - - - K - - - Helix-turn-helix
HEKLMFOH_01696 2.14e-91 - - - - - - - -
HEKLMFOH_01697 1.9e-132 - - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HEKLMFOH_01698 0.0 katA 1.11.1.6 - C ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 Belongs to the catalase family
HEKLMFOH_01699 2.77e-250 rsgA_2 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HEKLMFOH_01700 1.47e-239 - - - C - - - Aldo/keto reductase family
HEKLMFOH_01701 2.46e-52 - - - K - - - MerR, DNA binding
HEKLMFOH_01702 0.0 rtpR 1.17.4.2 - F ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 ribonucleoside-triphosphate reductase activity
HEKLMFOH_01703 3.68e-119 - - - S - - - Cob(I)alamin adenosyltransferase
HEKLMFOH_01704 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
HEKLMFOH_01705 2.64e-114 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HEKLMFOH_01706 1.4e-11 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HEKLMFOH_01707 1.93e-188 - - - - - - - -
HEKLMFOH_01708 2.11e-108 - - - T - - - Belongs to the universal stress protein A family
HEKLMFOH_01710 1.24e-257 yibE - - S - - - overlaps another CDS with the same product name
HEKLMFOH_01711 1.15e-163 yibF - - S - - - overlaps another CDS with the same product name
HEKLMFOH_01713 0.0 - - - S - - - Protein of unknown function DUF262
HEKLMFOH_01714 3.52e-176 - 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 Putative ATP-dependent Lon protease
HEKLMFOH_01715 3.93e-312 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
HEKLMFOH_01716 5.05e-52 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
HEKLMFOH_01717 4.94e-31 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
HEKLMFOH_01718 8.34e-178 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
HEKLMFOH_01719 8.73e-172 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
HEKLMFOH_01720 6.94e-218 - 1.1.1.29 - CH ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEKLMFOH_01721 1.26e-247 - - - L - - - Psort location Cytoplasmic, score
HEKLMFOH_01722 2.97e-41 - - - - - - - -
HEKLMFOH_01723 0.0 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HEKLMFOH_01724 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
HEKLMFOH_01725 1.34e-299 - - - - - - - -
HEKLMFOH_01726 9.42e-95 - - - K - - - Transcriptional regulator
HEKLMFOH_01727 0.0 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HEKLMFOH_01728 1.68e-165 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
HEKLMFOH_01729 3.25e-291 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEKLMFOH_01730 5.01e-138 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Peroxiredoxin
HEKLMFOH_01731 1.84e-80 - - - - - - - -
HEKLMFOH_01732 5.26e-148 - - - GM - - - NAD(P)H-binding
HEKLMFOH_01733 3.28e-61 - - - - - - - -
HEKLMFOH_01735 3.87e-89 - - - K - - - Helix-turn-helix domain
HEKLMFOH_01738 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HEKLMFOH_01739 4.64e-96 - - - K - - - Transcriptional regulator
HEKLMFOH_01740 3.49e-102 - - - S ko:K02348 - ko00000 Gnat family
HEKLMFOH_01741 8.6e-113 - - - K - - - Acetyltransferase (GNAT) domain
HEKLMFOH_01742 2.48e-209 - - - - - - - -
HEKLMFOH_01743 9.27e-145 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HEKLMFOH_01744 0.000218 - - - NU - - - Mycoplasma protein of unknown function, DUF285
HEKLMFOH_01745 5.06e-19 - - - S - - - Mor transcription activator family
HEKLMFOH_01747 1.34e-133 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
HEKLMFOH_01748 0.0 - - - S - - - Putative threonine/serine exporter
HEKLMFOH_01749 5.96e-205 yitS - - S - - - Uncharacterised protein, DegV family COG1307
HEKLMFOH_01750 2.52e-196 - - - C - - - Aldo keto reductase
HEKLMFOH_01751 1.42e-85 - - - S - - - Protein of unknown function (DUF1722)
HEKLMFOH_01752 1.13e-90 yqeB - - S - - - Pyrimidine dimer DNA glycosylase
HEKLMFOH_01753 0.0 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
HEKLMFOH_01754 4.53e-131 rcfB - - K - - - Crp-like helix-turn-helix domain
HEKLMFOH_01755 2.14e-112 - - - S - - - Protein of unknown function, DUF536
HEKLMFOH_01756 3.49e-219 - - - L - - - Initiator Replication protein
HEKLMFOH_01757 4.3e-40 - - - - - - - -
HEKLMFOH_01758 5.56e-82 - - - - - - - -
HEKLMFOH_01759 4.4e-138 - - - L - - - Integrase
HEKLMFOH_01760 1.11e-59 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
HEKLMFOH_01761 2.59e-77 - - - S - - - Bacterial toxin of type II toxin-antitoxin system, YafQ
HEKLMFOH_01762 6.31e-176 - - - K - - - Helix-turn-helix domain
HEKLMFOH_01764 9.82e-111 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HEKLMFOH_01765 3.01e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HEKLMFOH_01766 3.98e-272 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
HEKLMFOH_01767 2.33e-200 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
HEKLMFOH_01768 9.32e-191 yycI - - S - - - YycH protein
HEKLMFOH_01769 4.78e-307 yycH - - S - - - YycH protein
HEKLMFOH_01770 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEKLMFOH_01771 1.19e-170 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HEKLMFOH_01773 2.67e-166 - - - E - - - Matrixin
HEKLMFOH_01774 1.43e-52 - - - - - - - -
HEKLMFOH_01775 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HEKLMFOH_01776 1.18e-37 - - - - - - - -
HEKLMFOH_01777 1.82e-270 yttB - - EGP - - - Major Facilitator
HEKLMFOH_01778 1.77e-130 - - - S - - - NADPH-dependent FMN reductase
HEKLMFOH_01779 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HEKLMFOH_01781 2.22e-92 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HEKLMFOH_01782 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
HEKLMFOH_01783 4.07e-52 - - - S - - - response to heat
HEKLMFOH_01784 2.56e-129 - - - K - - - Bacterial regulatory proteins, tetR family
HEKLMFOH_01785 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HEKLMFOH_01786 2.37e-294 - - - Q - - - Imidazolonepropionase and related amidohydrolases
HEKLMFOH_01787 9.06e-185 - - - - - - - -
HEKLMFOH_01788 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HEKLMFOH_01789 2.68e-296 - - - Q - - - Imidazolonepropionase and related amidohydrolases
HEKLMFOH_01790 1.33e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HEKLMFOH_01791 5.15e-104 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HEKLMFOH_01792 1.36e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HEKLMFOH_01793 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEKLMFOH_01794 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEKLMFOH_01795 2.66e-270 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HEKLMFOH_01796 5.32e-48 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
HEKLMFOH_01797 6.73e-266 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HEKLMFOH_01798 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HEKLMFOH_01799 1.61e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
HEKLMFOH_01800 9.04e-78 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HEKLMFOH_01801 1.67e-185 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEKLMFOH_01802 2.25e-149 jag - - S ko:K06346 - ko00000 R3H domain protein
HEKLMFOH_01803 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HEKLMFOH_01804 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HEKLMFOH_01805 1.89e-82 - - - - - - - -
HEKLMFOH_01806 1.18e-50 - - - - - - - -
HEKLMFOH_01807 1.76e-162 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
HEKLMFOH_01808 5.5e-51 - - - - - - - -
HEKLMFOH_01809 8.07e-314 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HEKLMFOH_01810 1.29e-149 - - - S ko:K07118 - ko00000 NAD(P)H-binding
HEKLMFOH_01811 4.33e-127 - - - J - - - Acetyltransferase (GNAT) domain
HEKLMFOH_01812 2.51e-120 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
HEKLMFOH_01813 5.8e-290 - - - S - - - module of peptide synthetase
HEKLMFOH_01814 1.9e-278 tcaB - - EGP ko:K07552 - ko00000,ko02000 Drug resistance transporter Bcr CflA subfamily
HEKLMFOH_01815 3.92e-141 sip3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HEKLMFOH_01816 3.29e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HEKLMFOH_01817 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
HEKLMFOH_01818 1.34e-146 nt5e 3.1.3.18 - L ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
HEKLMFOH_01819 1.06e-68 - - - - - - - -
HEKLMFOH_01822 8.3e-117 - - - - - - - -
HEKLMFOH_01823 1.69e-193 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
HEKLMFOH_01824 2.12e-30 - - - - - - - -
HEKLMFOH_01825 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEKLMFOH_01826 1.04e-216 rhaS2 - - K - - - Transcriptional regulator, AraC family
HEKLMFOH_01827 0.0 - - - G ko:K03292 - ko00000 MFS/sugar transport protein
HEKLMFOH_01828 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
HEKLMFOH_01829 0.0 - - - S - - - Predicted membrane protein (DUF2207)
HEKLMFOH_01832 9.8e-113 ccl - - S - - - QueT transporter
HEKLMFOH_01833 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
HEKLMFOH_01834 3.77e-216 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
HEKLMFOH_01835 2.75e-170 drrB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
HEKLMFOH_01836 1.46e-212 drrA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HEKLMFOH_01837 8.73e-122 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HEKLMFOH_01838 2.46e-290 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HEKLMFOH_01839 4e-234 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
HEKLMFOH_01840 1.58e-133 - - - GM - - - NAD(P)H-binding
HEKLMFOH_01841 3.66e-77 - - - - - - - -
HEKLMFOH_01842 1.35e-237 pgdA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 polysaccharide deacetylase
HEKLMFOH_01843 3.82e-277 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HEKLMFOH_01844 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HEKLMFOH_01845 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HEKLMFOH_01846 3.48e-215 - - - - - - - -
HEKLMFOH_01847 5.05e-184 - - - K - - - Helix-turn-helix domain
HEKLMFOH_01849 5.44e-99 - - - M - - - domain protein
HEKLMFOH_01850 1.5e-277 - - - M - - - domain protein
HEKLMFOH_01851 3.09e-120 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
HEKLMFOH_01852 1.49e-93 ywnA - - K - - - Transcriptional regulator
HEKLMFOH_01853 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
HEKLMFOH_01854 9.12e-237 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
HEKLMFOH_01855 2.29e-273 msmK2 - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HEKLMFOH_01856 0.0 - - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HEKLMFOH_01857 5.87e-194 - - - U ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEKLMFOH_01858 1.67e-182 - - - U ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEKLMFOH_01859 9.28e-262 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase
HEKLMFOH_01860 1.02e-106 - - - L - - - Helix-turn-helix domain
HEKLMFOH_01861 5.84e-294 - - - S - - - Pyridine nucleotide-disulphide oxidoreductase
HEKLMFOH_01862 3.9e-29 - - - - - - - -
HEKLMFOH_01863 1.16e-191 - - - T - - - diguanylate cyclase
HEKLMFOH_01864 1.1e-157 - - - T - - - Putative diguanylate phosphodiesterase
HEKLMFOH_01865 1.96e-252 ysdE - - P - - - Citrate transporter
HEKLMFOH_01866 2.65e-220 - - - S - - - NAD:arginine ADP-ribosyltransferase
HEKLMFOH_01867 7.03e-40 cspA - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HEKLMFOH_01868 3.51e-19 - - - S - - - EamA-like transporter family
HEKLMFOH_01869 1.98e-69 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HEKLMFOH_01870 8.16e-105 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
HEKLMFOH_01871 5.94e-201 is18 - - L - - - COG2801 Transposase and inactivated derivatives
HEKLMFOH_01872 2.48e-52 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
HEKLMFOH_01873 2.49e-311 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HEKLMFOH_01874 4.97e-143 - - - - - - - -
HEKLMFOH_01875 1.85e-204 - 1.1.1.65 - C ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 ko00000,ko00001,ko01000 Aldo keto reductase
HEKLMFOH_01876 4.36e-200 - 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 Aminoglycoside 3-N-acetyltransferase
HEKLMFOH_01877 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HEKLMFOH_01878 2.22e-15 - - - C - - - Flavodoxin
HEKLMFOH_01879 7.81e-247 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HEKLMFOH_01880 0.0 eriC - - P ko:K03281 - ko00000 chloride
HEKLMFOH_01881 1.54e-135 - - - - - - - -
HEKLMFOH_01882 3.44e-70 ybjQ - - S - - - Belongs to the UPF0145 family
HEKLMFOH_01883 1.01e-119 - - - O - - - Zinc-dependent metalloprotease
HEKLMFOH_01897 8.69e-134 pncA - - Q - - - Isochorismatase family
HEKLMFOH_01898 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HEKLMFOH_01899 2.06e-169 - - - F - - - NUDIX domain
HEKLMFOH_01900 5.62e-69 - - - K - - - Bacterial regulatory proteins, tetR family
HEKLMFOH_01901 5.98e-212 - - - P - - - CorA-like Mg2+ transporter protein
HEKLMFOH_01902 1.5e-72 - - - L - - - Transposase DDE domain
HEKLMFOH_01903 8.3e-71 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
HEKLMFOH_01904 1.18e-78 - - - - - - - -
HEKLMFOH_01905 1.03e-55 - - - - - - - -
HEKLMFOH_01906 1.15e-35 - - - - - - - -
HEKLMFOH_01907 3.99e-123 - - - L - - - Resolvase, N terminal domain
HEKLMFOH_01908 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
HEKLMFOH_01909 2.23e-74 usp2 - - T - - - Belongs to the universal stress protein A family
HEKLMFOH_01910 1.36e-314 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HEKLMFOH_01911 1.18e-49 - - - K ko:K03709 - ko00000,ko03000 Helix-turn-helix diphteria tox regulatory element
HEKLMFOH_01913 6.08e-179 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HEKLMFOH_01914 4.71e-189 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEKLMFOH_01915 9.17e-131 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEKLMFOH_01916 1.8e-289 rodA - - D ko:K05837 - ko00000,ko03036 Cell cycle protein
HEKLMFOH_01917 7.67e-124 - - - - - - - -
HEKLMFOH_01919 4.28e-93 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase
HEKLMFOH_01920 6.12e-184 - - - S - - - Membrane
HEKLMFOH_01921 8.46e-239 tdh 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
HEKLMFOH_01922 1.81e-221 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
HEKLMFOH_01923 3.55e-99 - - - - - - - -
HEKLMFOH_01924 2.25e-260 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 dehydrogenase
HEKLMFOH_01925 6.92e-73 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
HEKLMFOH_01926 6.51e-69 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
HEKLMFOH_01927 8.42e-138 yokL3 - - J - - - Acetyltransferase (GNAT) domain
HEKLMFOH_01928 8.63e-188 - - - G - - - Belongs to the phosphoglycerate mutase family
HEKLMFOH_01930 0.0 treP 2.4.1.64 GH65 G ko:K05342 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HEKLMFOH_01931 7.09e-251 - - - I - - - alpha/beta hydrolase fold
HEKLMFOH_01932 0.0 xylP2 - - G - - - symporter
HEKLMFOH_01934 4.23e-21 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
HEKLMFOH_01935 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HEKLMFOH_01936 2.96e-106 - - - - - - - -
HEKLMFOH_01938 7.38e-228 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
HEKLMFOH_01939 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HEKLMFOH_01940 0.0 - 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HEKLMFOH_01941 2.41e-150 - - - - - - - -
HEKLMFOH_01942 1.69e-97 - - - K - - - helix_turn_helix, mercury resistance
HEKLMFOH_01943 8.19e-287 - - - C - - - Oxidoreductase
HEKLMFOH_01945 5.89e-90 - - - K - - - Transcriptional regulator, HxlR family
HEKLMFOH_01946 4.07e-271 mccF - - V - - - LD-carboxypeptidase
HEKLMFOH_01947 6.88e-229 - 3.2.2.1, 3.2.2.8 - F ko:K01239,ko:K10213 ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
HEKLMFOH_01948 6.64e-162 - - - K ko:K16326 - ko00000,ko03000 Cyclic nucleotide-monophosphate binding domain
HEKLMFOH_01949 2e-217 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEKLMFOH_01950 1.57e-281 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
HEKLMFOH_01951 4.37e-161 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HEKLMFOH_01952 1.47e-157 - - - S ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 GyrI-like small molecule binding domain
HEKLMFOH_01953 6.84e-90 - - - S - - - Protein of unknown function (DUF1398)
HEKLMFOH_01954 1.19e-129 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
HEKLMFOH_01955 2.68e-287 - - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEKLMFOH_01956 5.66e-159 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEKLMFOH_01957 1.09e-230 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HEKLMFOH_01958 1.19e-113 - - - K - - - Bacterial regulatory proteins, tetR family
HEKLMFOH_01959 1.05e-273 - - - EGP - - - Major Facilitator Superfamily
HEKLMFOH_01960 1.93e-108 thiW - - S - - - Thiamine-precursor transporter protein (ThiW)
HEKLMFOH_01961 4.7e-215 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
HEKLMFOH_01962 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
HEKLMFOH_01963 3.19e-208 mleR - - K - - - LysR family
HEKLMFOH_01964 5.05e-192 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
HEKLMFOH_01965 1.01e-276 aguA2 3.5.3.12 - E ko:K10536 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko01000 agmatine deiminase
HEKLMFOH_01966 1.16e-215 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
HEKLMFOH_01967 8.96e-277 aguA 3.5.3.12 - E ko:K10536 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko01000 agmatine deiminase
HEKLMFOH_01968 1.81e-307 aguD - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 Amino Acid
HEKLMFOH_01969 1.18e-252 ptcA 2.1.3.6 - E ko:K13252 - ko00000,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HEKLMFOH_01970 4.46e-311 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HEKLMFOH_01971 0.0 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 Amino acid permease
HEKLMFOH_01972 0.0 tdc 4.1.1.25 - E ko:K22330 ko00350,map00350 ko00000,ko00001,ko01000 Pyridoxal-dependent decarboxylase conserved domain
HEKLMFOH_01973 2.44e-306 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HEKLMFOH_01974 3.28e-52 - - - - - - - -
HEKLMFOH_01977 2.17e-267 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HEKLMFOH_01978 2.63e-36 - - - - - - - -
HEKLMFOH_01979 6.14e-202 - - - EG - - - EamA-like transporter family
HEKLMFOH_01980 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
HEKLMFOH_01981 2.5e-52 - - - - - - - -
HEKLMFOH_01982 7.18e-43 - - - S - - - Transglycosylase associated protein
HEKLMFOH_01983 4.68e-09 - - - S - - - Protein of unknown function (DUF2992)
HEKLMFOH_01984 1.51e-202 - - - K - - - Transcriptional regulator
HEKLMFOH_01985 0.0 - 3.2.1.45 GH30 G ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 TIM-barrel domain
HEKLMFOH_01986 1.52e-36 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HEKLMFOH_01987 8.61e-12 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HEKLMFOH_01990 4.49e-179 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
HEKLMFOH_01991 1.03e-144 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HEKLMFOH_01992 6.75e-157 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HEKLMFOH_01993 1.1e-276 - - - EGP ko:K08196 - ko00000,ko02000 Major Facilitator
HEKLMFOH_01994 4.3e-169 - - - S - - - Protein of unknown function
HEKLMFOH_01995 5.21e-225 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HEKLMFOH_01996 1.31e-210 - - - G - - - Belongs to the carbohydrate kinase PfkB family
HEKLMFOH_01997 0.0 - - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
HEKLMFOH_01998 1.7e-234 - - - O - - - ADP-ribosylglycohydrolase
HEKLMFOH_01999 4.81e-157 - - - K - - - UTRA
HEKLMFOH_02000 4.57e-201 yhaZ - - L - - - DNA alkylation repair enzyme
HEKLMFOH_02001 1.98e-162 - - - F - - - glutamine amidotransferase
HEKLMFOH_02002 0.0 fusA1 - - J - - - elongation factor G
HEKLMFOH_02003 1.06e-297 - - - EK - - - Aminotransferase, class I
HEKLMFOH_02005 2.24e-92 - - - S - - - COG NOG18757 non supervised orthologous group
HEKLMFOH_02006 3.49e-219 pmrB - - EGP - - - Major Facilitator Superfamily
HEKLMFOH_02007 8.32e-147 lacA 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HEKLMFOH_02008 2.4e-102 - - - - - - - -
HEKLMFOH_02009 4.83e-31 - - - - - - - -
HEKLMFOH_02010 1.11e-153 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
HEKLMFOH_02011 3.88e-285 - - - LO ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
HEKLMFOH_02012 1.72e-36 - - - K ko:K07729 - ko00000,ko03000 Transcriptional
HEKLMFOH_02013 2.11e-93 - - - - - - - -
HEKLMFOH_02014 0.0 - - - M - - - MucBP domain
HEKLMFOH_02015 8.2e-145 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
HEKLMFOH_02016 2.78e-127 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
HEKLMFOH_02017 1.28e-273 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HEKLMFOH_02018 6.74e-214 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HEKLMFOH_02019 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
HEKLMFOH_02023 2.42e-59 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
HEKLMFOH_02025 0.0 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
HEKLMFOH_02026 0.0 XK27_00340 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HEKLMFOH_02029 3.31e-108 - - - - - - - -
HEKLMFOH_02030 5.96e-238 tnp2 - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
HEKLMFOH_02032 5.98e-55 - - - - - - - -
HEKLMFOH_02033 1.39e-36 - - - - - - - -
HEKLMFOH_02034 6.96e-30 - - - EGP - - - Major Facilitator
HEKLMFOH_02035 3.33e-133 tnpR - - L - - - Resolvase, N terminal domain
HEKLMFOH_02038 2.09e-70 - - - S ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Glycine cleavage H-protein
HEKLMFOH_02039 7.89e-213 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HEKLMFOH_02040 2.05e-181 yejC - - S - - - Protein of unknown function (DUF1003)
HEKLMFOH_02041 1.08e-138 - - - K ko:K06977 - ko00000 acetyltransferase
HEKLMFOH_02042 7.97e-113 nimA - - S ko:K07005 - ko00000 resistance protein
HEKLMFOH_02043 1.2e-117 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HEKLMFOH_02044 1.22e-93 - - - - - - - -
HEKLMFOH_02045 1.91e-281 - - - EGP - - - Transmembrane secretion effector
HEKLMFOH_02046 1.89e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
HEKLMFOH_02047 3.39e-67 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
HEKLMFOH_02048 1.18e-139 azlC - - E - - - branched-chain amino acid
HEKLMFOH_02049 1.27e-50 - - - K - - - MerR HTH family regulatory protein
HEKLMFOH_02050 1.85e-155 - - - S - - - Domain of unknown function (DUF4811)
HEKLMFOH_02051 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
HEKLMFOH_02052 2.28e-102 - - - K - - - MerR HTH family regulatory protein
HEKLMFOH_02053 8.61e-132 - - - K - - - Acetyltransferase (GNAT) domain
HEKLMFOH_02054 4.51e-205 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
HEKLMFOH_02055 4.18e-155 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
HEKLMFOH_02056 1.2e-161 - - - S - - - Putative threonine/serine exporter
HEKLMFOH_02057 7.85e-96 - - - S - - - Threonine/Serine exporter, ThrE
HEKLMFOH_02058 4.14e-154 - - - I - - - phosphatase
HEKLMFOH_02059 5.08e-169 - - - I - - - alpha/beta hydrolase fold
HEKLMFOH_02061 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
HEKLMFOH_02062 2.42e-147 dgk2 - - F - - - deoxynucleoside kinase
HEKLMFOH_02063 6.3e-291 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HEKLMFOH_02072 9.4e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
HEKLMFOH_02073 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HEKLMFOH_02074 1.64e-136 - - - K - - - Bacterial regulatory proteins, tetR family
HEKLMFOH_02075 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEKLMFOH_02076 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEKLMFOH_02077 3.58e-156 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
HEKLMFOH_02078 1.46e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HEKLMFOH_02079 7.17e-109 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HEKLMFOH_02080 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HEKLMFOH_02081 2.15e-299 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
HEKLMFOH_02082 4.46e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HEKLMFOH_02083 1.19e-150 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HEKLMFOH_02084 5.45e-138 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HEKLMFOH_02085 4.65e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HEKLMFOH_02086 1.63e-199 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HEKLMFOH_02087 7.56e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HEKLMFOH_02088 9.77e-73 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HEKLMFOH_02089 1.63e-154 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HEKLMFOH_02090 3.95e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HEKLMFOH_02091 1.58e-33 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HEKLMFOH_02092 3.69e-54 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HEKLMFOH_02093 1.04e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HEKLMFOH_02094 4.1e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HEKLMFOH_02095 3.53e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HEKLMFOH_02096 3.78e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HEKLMFOH_02097 1.24e-122 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HEKLMFOH_02098 8.69e-76 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HEKLMFOH_02099 3.46e-110 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HEKLMFOH_02100 1.2e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
HEKLMFOH_02101 1.67e-90 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HEKLMFOH_02102 1.66e-304 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HEKLMFOH_02103 5.28e-160 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HEKLMFOH_02104 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HEKLMFOH_02105 2.37e-79 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HEKLMFOH_02106 6.34e-81 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HEKLMFOH_02107 2.1e-219 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEKLMFOH_02108 6.64e-82 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HEKLMFOH_02109 6.89e-195 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEKLMFOH_02110 2.17e-208 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEKLMFOH_02111 2.79e-183 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEKLMFOH_02112 1.11e-193 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HEKLMFOH_02113 6.51e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HEKLMFOH_02114 3.52e-83 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HEKLMFOH_02115 2.09e-247 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HEKLMFOH_02116 1.42e-303 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
HEKLMFOH_02117 9.37e-150 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
HEKLMFOH_02118 2.9e-253 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HEKLMFOH_02119 1.57e-134 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
HEKLMFOH_02120 1.84e-280 ribA 3.5.4.25, 4.1.99.12 - H ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HEKLMFOH_02121 2.05e-104 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HEKLMFOH_02122 7.66e-252 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
HEKLMFOH_02123 0.0 - - - E ko:K03294 - ko00000 Amino Acid
HEKLMFOH_02124 1.53e-244 lplL 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Bacterial lipoate protein ligase C-terminus
HEKLMFOH_02125 1.34e-211 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HEKLMFOH_02126 1.2e-120 epsB - - M - - - biosynthesis protein
HEKLMFOH_02127 5.55e-169 ywqD - - D - - - Capsular exopolysaccharide family
HEKLMFOH_02128 6.76e-178 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
HEKLMFOH_02129 1.93e-108 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
HEKLMFOH_02130 6.42e-101 - 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Belongs to the glycosyltransferase 26 family
HEKLMFOH_02131 1.89e-157 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphatase and related hydrolases of the PHP family
HEKLMFOH_02132 4.58e-114 - - - K - - - FR47-like protein
HEKLMFOH_02133 1.7e-30 - - - S - - - Family of unknown function (DUF5388)
HEKLMFOH_02134 3.66e-153 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
HEKLMFOH_02135 8.07e-69 - - - L - - - recombinase activity
HEKLMFOH_02136 7.12e-32 - - - S - - - Family of unknown function (DUF5388)
HEKLMFOH_02137 1.18e-184 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
HEKLMFOH_02138 5.29e-86 - - - L - - - the current gene model (or a revised gene model) may contain a frame shift
HEKLMFOH_02139 2.47e-214 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HEKLMFOH_02140 5.7e-301 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
HEKLMFOH_02141 2.18e-245 - - - L - - - Transposase and inactivated derivatives, IS30 family
HEKLMFOH_02142 1.43e-116 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HEKLMFOH_02143 1.92e-240 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HEKLMFOH_02144 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
HEKLMFOH_02145 1.24e-277 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HEKLMFOH_02146 8.9e-219 ypjC - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HEKLMFOH_02147 8.7e-296 XK27_05225 - - S - - - Tetratricopeptide repeat protein
HEKLMFOH_02148 4.58e-54 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HEKLMFOH_02149 2.29e-315 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HEKLMFOH_02150 5.63e-279 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HEKLMFOH_02151 9.33e-153 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HEKLMFOH_02152 4.61e-63 - - - M - - - Lysin motif
HEKLMFOH_02153 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HEKLMFOH_02154 9.21e-244 - - - S - - - Helix-turn-helix domain
HEKLMFOH_02155 1.11e-121 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HEKLMFOH_02156 2.58e-166 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HEKLMFOH_02157 1.7e-133 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HEKLMFOH_02158 1.54e-170 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HEKLMFOH_02159 7.96e-94 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEKLMFOH_02160 2.17e-212 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
HEKLMFOH_02161 2.65e-215 yitL - - S ko:K00243 - ko00000 S1 domain
HEKLMFOH_02162 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
HEKLMFOH_02163 7.92e-162 tal2 2.2.1.2 - H ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase/Fructose-6-phosphate aldolase
HEKLMFOH_02164 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HEKLMFOH_02165 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HEKLMFOH_02166 3.57e-301 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HEKLMFOH_02167 3.19e-199 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HEKLMFOH_02168 1.61e-162 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HEKLMFOH_02169 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
HEKLMFOH_02170 1.21e-115 - - - K - - - Transcriptional regulator
HEKLMFOH_02171 9.66e-252 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HEKLMFOH_02172 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HEKLMFOH_02173 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
HEKLMFOH_02174 7.13e-227 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
HEKLMFOH_02175 7.51e-194 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HEKLMFOH_02176 1.27e-217 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HEKLMFOH_02177 1.93e-81 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
HEKLMFOH_02178 1.22e-112 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HEKLMFOH_02179 4.84e-231 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
HEKLMFOH_02180 1.72e-94 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
HEKLMFOH_02181 1.45e-89 ydeP - - K - - - Transcriptional regulator, HxlR family
HEKLMFOH_02182 2.2e-250 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HEKLMFOH_02183 2.21e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HEKLMFOH_02184 7.18e-195 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HEKLMFOH_02185 5.18e-221 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HEKLMFOH_02186 3.08e-308 - 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycerophosphotransferase
HEKLMFOH_02187 1.84e-194 tagG - - U ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
HEKLMFOH_02188 9.98e-262 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HEKLMFOH_02189 3.33e-208 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HEKLMFOH_02190 2.94e-124 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HEKLMFOH_02191 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HEKLMFOH_02192 9.74e-315 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HEKLMFOH_02193 5.93e-129 - - - - - - - -
HEKLMFOH_02194 3.46e-206 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
HEKLMFOH_02195 4.92e-209 - - - G - - - Fructosamine kinase
HEKLMFOH_02196 3.17e-149 - - - S - - - HAD-hyrolase-like
HEKLMFOH_02197 2.24e-98 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HEKLMFOH_02198 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HEKLMFOH_02199 9.64e-81 - - - - - - - -
HEKLMFOH_02200 7.68e-173 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HEKLMFOH_02201 9.42e-232 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
HEKLMFOH_02202 1.79e-71 - - - - - - - -
HEKLMFOH_02203 7.94e-65 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HEKLMFOH_02204 6.81e-83 - - - - - - - -
HEKLMFOH_02206 7.67e-56 - - - - - - - -
HEKLMFOH_02208 2.82e-281 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
HEKLMFOH_02211 1.26e-242 - - - L ko:K07482 - ko00000 Helix-turn-helix domain
HEKLMFOH_02212 2.79e-224 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HEKLMFOH_02213 2.69e-226 - - - L ko:K07482 - ko00000 Integrase core domain
HEKLMFOH_02214 3.9e-88 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
HEKLMFOH_02215 1.49e-97 - - - L - - - Transposase DDE domain
HEKLMFOH_02216 6.94e-59 - - - L ko:K07473 - ko00000,ko02048 Addiction module antitoxin, RelB DinJ family
HEKLMFOH_02217 3.24e-147 - - - L - - - Transposase
HEKLMFOH_02218 1.46e-114 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
HEKLMFOH_02219 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
HEKLMFOH_02220 5.47e-178 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HEKLMFOH_02221 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
HEKLMFOH_02222 0.0 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEKLMFOH_02223 8.83e-257 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
HEKLMFOH_02224 5.73e-136 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HEKLMFOH_02225 1.96e-223 - - - K - - - transcriptional regulator, ArsR family
HEKLMFOH_02226 1.18e-255 abf - - G - - - Belongs to the glycosyl hydrolase 43 family
HEKLMFOH_02227 4.55e-303 lacY - - G ko:K02532 - ko00000,ko02000 Oligosaccharide H symporter
HEKLMFOH_02228 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
HEKLMFOH_02229 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HEKLMFOH_02230 1.56e-93 - - - K - - - Transcriptional regulator
HEKLMFOH_02231 4.91e-122 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
HEKLMFOH_02232 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HEKLMFOH_02233 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
HEKLMFOH_02234 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
HEKLMFOH_02235 2.56e-95 - - - S - - - Iron-sulphur cluster biosynthesis
HEKLMFOH_02236 0.0 rafA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HEKLMFOH_02237 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HEKLMFOH_02238 6.78e-136 - - - K - - - acetyltransferase
HEKLMFOH_02239 1.68e-225 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
HEKLMFOH_02240 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HEKLMFOH_02241 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
HEKLMFOH_02242 3.18e-155 pgm3 - - G - - - phosphoglycerate mutase
HEKLMFOH_02243 1.14e-229 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HEKLMFOH_02244 1.24e-259 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HEKLMFOH_02245 1.11e-238 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEKLMFOH_02246 3.02e-204 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEKLMFOH_02247 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HEKLMFOH_02248 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HEKLMFOH_02249 1.19e-296 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HEKLMFOH_02250 1.13e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HEKLMFOH_02251 1.5e-142 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HEKLMFOH_02252 4.49e-195 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HEKLMFOH_02253 8.35e-175 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HEKLMFOH_02254 1.13e-220 - - - - - - - -
HEKLMFOH_02255 4.52e-47 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
HEKLMFOH_02256 2.62e-109 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HEKLMFOH_02257 1.3e-97 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
HEKLMFOH_02258 6.89e-97 apfA 3.6.1.61 - F ko:K18445 ko00230,map00230 ko00000,ko00001,ko01000 Nudix hydrolase
HEKLMFOH_02259 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
HEKLMFOH_02260 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HEKLMFOH_02261 9.02e-228 - 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HEKLMFOH_02262 4.19e-113 yciB - - M - - - ErfK YbiS YcfS YnhG
HEKLMFOH_02263 0.0 - - - S - - - ABC transporter, ATP-binding protein
HEKLMFOH_02264 1.57e-89 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEKLMFOH_02265 2.69e-158 XK27_07075 - - S ko:K07052 - ko00000 CAAX protease self-immunity
HEKLMFOH_02266 1.14e-155 - - - S ko:K05833 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HEKLMFOH_02267 2.33e-214 WQ51_06230 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HEKLMFOH_02268 9.9e-216 XK27_00670 - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HEKLMFOH_02269 5.11e-210 - - - S - - - Uncharacterised protein, DegV family COG1307
HEKLMFOH_02270 4.81e-228 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HEKLMFOH_02271 1.27e-196 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HEKLMFOH_02272 3.26e-177 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEKLMFOH_02274 1.71e-204 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
HEKLMFOH_02275 5.52e-161 - - - P - - - integral membrane protein, YkoY family
HEKLMFOH_02276 8.84e-179 - - - L - - - COG2801 Transposase and inactivated derivatives
HEKLMFOH_02277 1.58e-126 repA - - S - - - Replication initiator protein A
HEKLMFOH_02279 3.22e-270 coiA - - S ko:K06198 - ko00000 Competence protein
HEKLMFOH_02280 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
HEKLMFOH_02281 3.19e-204 degV1 - - S - - - DegV family
HEKLMFOH_02282 1.7e-148 yjbH - - Q - - - Thioredoxin
HEKLMFOH_02283 9.43e-154 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
HEKLMFOH_02284 1.29e-193 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HEKLMFOH_02285 7.1e-223 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HEKLMFOH_02286 4.63e-62 - - - S - - - Pfam Methyltransferase
HEKLMFOH_02287 1.23e-34 - - - S - - - Pfam Methyltransferase
HEKLMFOH_02288 2.97e-79 - - - M - - - UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HEKLMFOH_02289 2.22e-83 - - - S - - - Pfam Methyltransferase
HEKLMFOH_02290 1.11e-37 - - - - - - - -
HEKLMFOH_02291 0.0 tagE2 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HEKLMFOH_02292 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HEKLMFOH_02293 4.02e-19 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HEKLMFOH_02294 3.71e-139 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
HEKLMFOH_02295 7.47e-262 XK27_05220 - - S - - - AI-2E family transporter
HEKLMFOH_02296 3.2e-207 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
HEKLMFOH_02297 1.72e-125 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HEKLMFOH_02298 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HEKLMFOH_02299 4.92e-18 - - - S - - - Protein of unknown function (DUF4044)
HEKLMFOH_02300 8.72e-80 - - - S - - - Protein of unknown function (DUF3397)
HEKLMFOH_02301 1.38e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HEKLMFOH_02302 1.23e-226 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HEKLMFOH_02303 7.35e-81 ftsL - - D - - - Cell division protein FtsL
HEKLMFOH_02304 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HEKLMFOH_02305 3.06e-236 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HEKLMFOH_02306 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HEKLMFOH_02307 1.69e-256 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HEKLMFOH_02308 9.4e-198 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HEKLMFOH_02309 7.41e-311 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HEKLMFOH_02310 1.48e-287 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HEKLMFOH_02311 2.58e-98 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HEKLMFOH_02312 3.42e-55 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
HEKLMFOH_02313 7.18e-187 ylmH - - S - - - S4 domain protein
HEKLMFOH_02314 3.87e-134 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
HEKLMFOH_02315 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HEKLMFOH_02316 4.08e-47 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HEKLMFOH_02317 2.49e-123 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
HEKLMFOH_02318 1.36e-47 - - - - - - - -
HEKLMFOH_02319 3.68e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HEKLMFOH_02320 2.86e-288 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HEKLMFOH_02321 1.79e-77 XK27_04120 - - S - - - Putative amino acid metabolism
HEKLMFOH_02322 1.77e-284 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HEKLMFOH_02323 9.09e-156 pgm6 - - G - - - phosphoglycerate mutase
HEKLMFOH_02324 1.88e-152 - - - S - - - repeat protein
HEKLMFOH_02325 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HEKLMFOH_02326 4.45e-227 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HEKLMFOH_02327 3.99e-165 - - - S - - - Protein of unknown function (DUF1275)
HEKLMFOH_02328 6.33e-157 yckA - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HEKLMFOH_02329 1.99e-205 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HEKLMFOH_02330 0.0 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
HEKLMFOH_02331 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HEKLMFOH_02332 5.89e-203 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HEKLMFOH_02333 2.74e-242 yghZ - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
HEKLMFOH_02334 8.04e-237 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HEKLMFOH_02335 3.56e-206 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEKLMFOH_02336 0.0 tkt2 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HEKLMFOH_02337 4.08e-216 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 NlpC/P60 family
HEKLMFOH_02338 4.06e-220 ypuA - - S - - - Protein of unknown function (DUF1002)
HEKLMFOH_02339 8.77e-210 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
HEKLMFOH_02340 6.66e-39 - - - - - - - -

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)