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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
NPEPGNMH_00001	2.52e-122	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
NPEPGNMH_00002	1.2e-122	-	-	-	M	-	-	-	FR47-like protein
NPEPGNMH_00003	4.54e-258	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
NPEPGNMH_00004	4.06e-110	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
NPEPGNMH_00005	1.95e-109	yuaE	-	-	S	-	-	-	DinB superfamily
NPEPGNMH_00006	8.58e-139	yuaD	-	-	-	-	-	-	-
NPEPGNMH_00007	4.26e-292	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
NPEPGNMH_00008	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
NPEPGNMH_00009	3.53e-123	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
NPEPGNMH_00010	5.83e-118	yuaB	-	-	-	-	-	-	-
NPEPGNMH_00011	1.83e-157	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
NPEPGNMH_00012	1.85e-301	-	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium
NPEPGNMH_00013	3.31e-52	yubF	-	-	S	-	-	-	yiaA/B two helix domain
NPEPGNMH_00014	1.87e-196	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NPEPGNMH_00015	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
NPEPGNMH_00016	6.82e-114	cdoA	1.13.11.20	-	S	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100	ko00000,ko00001,ko01000	Cysteine dioxygenase type I
NPEPGNMH_00018	6.02e-183	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NPEPGNMH_00019	3.8e-256	yubA	-	-	S	-	-	-	transporter activity
NPEPGNMH_00020	9.11e-236	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
NPEPGNMH_00021	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
NPEPGNMH_00022	4.94e-73	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
NPEPGNMH_00023	0.0	rhaB	2.7.1.5	-	G	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NPEPGNMH_00024	1.52e-120	yulB	-	-	K	ko:K02530,ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
NPEPGNMH_00025	0.0	yuxG	-	-	IQ	-	-	-	Class II Aldolase and Adducin N-terminal domain
NPEPGNMH_00026	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
NPEPGNMH_00027	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
NPEPGNMH_00028	6.34e-300	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
NPEPGNMH_00029	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
NPEPGNMH_00030	1.06e-181	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
NPEPGNMH_00031	5e-48	-	-	-	-	-	-	-	-
NPEPGNMH_00032	3.63e-95	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
NPEPGNMH_00033	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
NPEPGNMH_00034	5.48e-299	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
NPEPGNMH_00035	4.8e-150	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
NPEPGNMH_00036	1.35e-51	-	-	-	-	-	-	-	-
NPEPGNMH_00037	2.12e-70	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
NPEPGNMH_00038	1.76e-233	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
NPEPGNMH_00039	4.22e-95	yugN	-	-	S	-	-	-	YugN-like family
NPEPGNMH_00041	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
NPEPGNMH_00042	5.56e-291	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
NPEPGNMH_00043	2.85e-287	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
NPEPGNMH_00044	2.21e-46	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
NPEPGNMH_00045	5e-83	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
NPEPGNMH_00046	6.62e-256	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
NPEPGNMH_00047	6.74e-112	alaR	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_00048	1.2e-201	yugF	-	-	I	-	-	-	Hydrolase
NPEPGNMH_00049	6.7e-56	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
NPEPGNMH_00050	2.09e-289	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NPEPGNMH_00051	1.59e-173	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NPEPGNMH_00052	4.3e-92	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
NPEPGNMH_00053	8.49e-150	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
NPEPGNMH_00055	1.96e-245	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
NPEPGNMH_00056	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
NPEPGNMH_00057	3.31e-98	yuxK	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_00058	4.19e-113	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
NPEPGNMH_00059	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
NPEPGNMH_00060	1.14e-162	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
NPEPGNMH_00061	6.34e-254	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
NPEPGNMH_00062	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NPEPGNMH_00063	1.57e-237	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NPEPGNMH_00064	1.47e-216	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NPEPGNMH_00065	9.73e-310	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	COG3493 Na citrate symporter
NPEPGNMH_00066	7.06e-22	-	-	-	-	-	-	-	-
NPEPGNMH_00067	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NPEPGNMH_00068	7.66e-91	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NPEPGNMH_00069	1.72e-66	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NPEPGNMH_00070	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NPEPGNMH_00071	7.39e-103	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NPEPGNMH_00072	2.23e-51	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NPEPGNMH_00073	5.97e-79	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
NPEPGNMH_00074	3.18e-84	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
NPEPGNMH_00075	2.06e-150	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPEPGNMH_00076	4.23e-276	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NPEPGNMH_00077	1.62e-97	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NPEPGNMH_00078	8.43e-70	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NPEPGNMH_00080	1.4e-209	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Polyprenyl synthetase
NPEPGNMH_00081	6.29e-10	-	-	-	S	-	-	-	DegQ (SacQ) family
NPEPGNMH_00082	9.63e-08	-	-	-	-	-	-	-	-
NPEPGNMH_00083	2.92e-298	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
NPEPGNMH_00084	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NPEPGNMH_00085	5.65e-135	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
NPEPGNMH_00086	1.32e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
NPEPGNMH_00087	1.63e-52	yueH	-	-	S	-	-	-	YueH-like protein
NPEPGNMH_00088	1.23e-43	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
NPEPGNMH_00089	4.72e-245	yueF	-	-	S	-	-	-	transporter activity
NPEPGNMH_00090	3.97e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF2283)
NPEPGNMH_00091	8.4e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
NPEPGNMH_00092	3.26e-111	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
NPEPGNMH_00093	6.1e-171	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPEPGNMH_00094	4.37e-97	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
NPEPGNMH_00095	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
NPEPGNMH_00096	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NPEPGNMH_00097	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NPEPGNMH_00098	4.28e-271	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
NPEPGNMH_00099	1.93e-54	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
NPEPGNMH_00100	3.93e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
NPEPGNMH_00101	1.03e-292	yukF	-	-	QT	-	-	-	Transcriptional regulator
NPEPGNMH_00102	4.9e-263	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
NPEPGNMH_00103	2.07e-169	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
NPEPGNMH_00104	1.42e-47	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
NPEPGNMH_00105	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPEPGNMH_00106	3.83e-229	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
NPEPGNMH_00107	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
NPEPGNMH_00108	7.34e-291	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
NPEPGNMH_00109	1.43e-178	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
NPEPGNMH_00110	1.55e-213	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
NPEPGNMH_00111	2.36e-157	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
NPEPGNMH_00112	8.33e-125	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
NPEPGNMH_00113	3.65e-279	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
NPEPGNMH_00114	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NPEPGNMH_00115	8.63e-102	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
NPEPGNMH_00116	1.69e-151	yuiC	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_00117	9.78e-47	yuiB	-	-	S	-	-	-	Putative membrane protein
NPEPGNMH_00118	4.16e-301	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
NPEPGNMH_00119	1.16e-240	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
NPEPGNMH_00121	1.15e-237	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NPEPGNMH_00122	2.96e-151	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Putative FMN-binding domain
NPEPGNMH_00123	6.88e-116	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPEPGNMH_00124	6.81e-83	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
NPEPGNMH_00125	3.9e-208	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NPEPGNMH_00126	1.54e-270	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NPEPGNMH_00127	1.74e-52	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
NPEPGNMH_00128	1.12e-253	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
NPEPGNMH_00129	6.61e-75	yuzD	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_00130	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
NPEPGNMH_00131	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
NPEPGNMH_00132	2.57e-221	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NPEPGNMH_00133	2.4e-253	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NPEPGNMH_00134	6.49e-268	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
NPEPGNMH_00135	6.19e-19	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
NPEPGNMH_00136	4.63e-255	yutH	-	-	S	-	-	-	Spore coat protein
NPEPGNMH_00137	3.34e-112	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
NPEPGNMH_00138	9.12e-183	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NPEPGNMH_00139	2.38e-99	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
NPEPGNMH_00140	3.2e-63	yutD	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_00141	9.45e-145	yutC	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NPEPGNMH_00142	1.37e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NPEPGNMH_00143	2.66e-252	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
NPEPGNMH_00144	4.25e-172	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
NPEPGNMH_00145	3.41e-65	yunC	-	-	S	-	-	-	Domain of unknown function (DUF1805)
NPEPGNMH_00146	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
NPEPGNMH_00147	6.51e-181	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NPEPGNMH_00148	4.26e-220	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
NPEPGNMH_00149	2.72e-82	yunG	-	-	-	-	-	-	-
NPEPGNMH_00150	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
NPEPGNMH_00151	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
NPEPGNMH_00152	1.46e-300	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	Permease family
NPEPGNMH_00153	1.65e-285	pbuX	-	-	F	ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
NPEPGNMH_00154	0.0	-	1.7.3.3, 4.1.1.97	-	Q	ko:K16838	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
NPEPGNMH_00155	1.41e-79	pucM	3.5.2.17	-	S	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
NPEPGNMH_00156	1.3e-126	-	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03518	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
NPEPGNMH_00157	0.0	pucD	1.17.1.4	-	C	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NPEPGNMH_00158	4.85e-194	pucC	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03519	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
NPEPGNMH_00159	2.62e-144	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
NPEPGNMH_00160	5.12e-243	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NPEPGNMH_00162	8.51e-306	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
NPEPGNMH_00163	4.9e-303	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NPEPGNMH_00164	6.53e-218	bsn	-	-	L	-	-	-	Ribonuclease
NPEPGNMH_00165	2.95e-263	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NPEPGNMH_00166	7.46e-176	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
NPEPGNMH_00167	9.57e-209	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
NPEPGNMH_00168	1.94e-216	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
NPEPGNMH_00169	1.24e-199	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NPEPGNMH_00170	2.46e-308	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
NPEPGNMH_00171	2.24e-236	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
NPEPGNMH_00172	1.2e-87	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
NPEPGNMH_00173	1.42e-268	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
NPEPGNMH_00175	3.35e-56	-	-	-	-	-	-	-	-
NPEPGNMH_00176	2.14e-87	yurT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPEPGNMH_00177	1.07e-57	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
NPEPGNMH_00178	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
NPEPGNMH_00179	6.26e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
NPEPGNMH_00180	2.81e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NPEPGNMH_00181	7.43e-313	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
NPEPGNMH_00182	3.82e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NPEPGNMH_00183	5.44e-81	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NPEPGNMH_00184	1.01e-189	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
NPEPGNMH_00185	6.5e-126	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
NPEPGNMH_00186	2.15e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NPEPGNMH_00187	1.53e-74	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
NPEPGNMH_00188	2e-73	yusE	-	-	CO	-	-	-	Thioredoxin
NPEPGNMH_00189	1.32e-97	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
NPEPGNMH_00190	7.34e-54	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
NPEPGNMH_00191	5.91e-85	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
NPEPGNMH_00192	1.01e-83	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
NPEPGNMH_00193	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
NPEPGNMH_00194	1.34e-278	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
NPEPGNMH_00195	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
NPEPGNMH_00196	2.09e-212	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
NPEPGNMH_00197	2.23e-54	-	-	-	-	-	-	-	-
NPEPGNMH_00198	2.12e-70	yusN	-	-	M	-	-	-	Coat F domain
NPEPGNMH_00199	3.83e-99	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
NPEPGNMH_00200	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
NPEPGNMH_00201	1.76e-86	yusQ	-	-	S	-	-	-	Tautomerase enzyme
NPEPGNMH_00202	5.64e-84	yusR	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
NPEPGNMH_00203	4.48e-67	yusR	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
NPEPGNMH_00204	1.52e-206	gltR	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
NPEPGNMH_00205	3.66e-64	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
NPEPGNMH_00206	1.06e-196	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NPEPGNMH_00207	2.01e-87	-	-	-	S	-	-	-	YusW-like protein
NPEPGNMH_00208	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
NPEPGNMH_00209	1.21e-41	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
NPEPGNMH_00210	6.65e-198	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
NPEPGNMH_00211	1.07e-104	fri	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
NPEPGNMH_00212	9.63e-306	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NPEPGNMH_00213	2.23e-164	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPEPGNMH_00214	0.0	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NPEPGNMH_00215	4.68e-76	yuxN	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_00216	1.62e-81	yuxN	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_00217	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NPEPGNMH_00218	4.48e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
NPEPGNMH_00219	4.81e-230	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
NPEPGNMH_00220	2.9e-253	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
NPEPGNMH_00221	1.22e-249	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
NPEPGNMH_00222	9.39e-141	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPEPGNMH_00223	4.06e-246	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NPEPGNMH_00224	5.39e-164	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
NPEPGNMH_00225	6.57e-178	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
NPEPGNMH_00226	4.22e-144	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
NPEPGNMH_00227	1.51e-82	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
NPEPGNMH_00228	1.13e-288	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
NPEPGNMH_00229	8.21e-133	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
NPEPGNMH_00230	0.0	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NPEPGNMH_00231	3.29e-237	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPEPGNMH_00232	5.15e-219	btuF	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NPEPGNMH_00233	5.21e-182	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
NPEPGNMH_00234	1.32e-219	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
NPEPGNMH_00235	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
NPEPGNMH_00236	2.08e-169	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPEPGNMH_00237	5.07e-32	-	-	-	-	-	-	-	-
NPEPGNMH_00238	6.74e-126	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
NPEPGNMH_00239	3.46e-26	-	-	-	S	-	-	-	YvrJ protein family
NPEPGNMH_00240	1.59e-292	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
NPEPGNMH_00241	9.89e-86	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
NPEPGNMH_00242	1.17e-272	yvrN	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
NPEPGNMH_00243	1.62e-159	yvrO	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPGNMH_00244	3.61e-231	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter rnd family, mfp subunit
NPEPGNMH_00245	2.92e-191	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NPEPGNMH_00246	4.78e-226	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPEPGNMH_00247	1.48e-237	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPEPGNMH_00248	1.14e-227	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NPEPGNMH_00250	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
NPEPGNMH_00252	2.38e-109	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
NPEPGNMH_00253	1.5e-187	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
NPEPGNMH_00254	3.9e-191	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
NPEPGNMH_00255	5.58e-218	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
NPEPGNMH_00256	6.57e-179	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
NPEPGNMH_00257	6.08e-154	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
NPEPGNMH_00258	4.54e-203	yvgN	-	-	S	-	-	-	reductase
NPEPGNMH_00259	7.97e-113	yvgO	-	-	-	-	-	-	-
NPEPGNMH_00260	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
NPEPGNMH_00261	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NPEPGNMH_00262	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NPEPGNMH_00263	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
NPEPGNMH_00264	3.88e-140	yvgT	-	-	S	-	-	-	membrane
NPEPGNMH_00265	1.99e-95	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
NPEPGNMH_00266	3.45e-137	bdbD	-	-	O	-	-	-	Thioredoxin
NPEPGNMH_00267	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
NPEPGNMH_00268	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
NPEPGNMH_00269	3.66e-41	copZ	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Copper resistance protein CopZ
NPEPGNMH_00270	6.89e-65	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
NPEPGNMH_00271	7.89e-254	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
NPEPGNMH_00272	3.59e-154	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NPEPGNMH_00273	0.0	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
NPEPGNMH_00274	2.02e-97	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
NPEPGNMH_00275	4.28e-72	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
NPEPGNMH_00276	8.9e-131	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NPEPGNMH_00277	3.96e-182	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
NPEPGNMH_00279	2.4e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NPEPGNMH_00280	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NPEPGNMH_00281	3.43e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
NPEPGNMH_00282	1.87e-35	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
NPEPGNMH_00283	4.03e-196	yvaM	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Serine aminopeptidase, S33
NPEPGNMH_00284	3.44e-48	yvzC	-	-	K	-	-	-	transcriptional
NPEPGNMH_00285	4.08e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
NPEPGNMH_00286	1.19e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
NPEPGNMH_00287	3.85e-72	yvaP	-	-	K	-	-	-	transcriptional
NPEPGNMH_00288	0.0	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
NPEPGNMH_00289	2.26e-144	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
NPEPGNMH_00290	2.89e-221	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NPEPGNMH_00291	1.55e-142	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
NPEPGNMH_00292	6.29e-272	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NPEPGNMH_00293	1.15e-122	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
NPEPGNMH_00294	4.79e-224	-	-	-	-	-	-	-	-
NPEPGNMH_00296	8.32e-133	yvaZ	-	-	S	-	-	-	Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
NPEPGNMH_00297	9.63e-60	sdpR	-	-	K	-	-	-	transcriptional
NPEPGNMH_00298	1.03e-146	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
NPEPGNMH_00299	2.58e-223	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NPEPGNMH_00300	5.63e-145	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
NPEPGNMH_00301	5.58e-270	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NPEPGNMH_00302	1.74e-130	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
NPEPGNMH_00303	9.68e-136	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
NPEPGNMH_00304	1.03e-145	yvbH	-	-	S	-	-	-	YvbH-like oligomerisation region
NPEPGNMH_00305	2.38e-158	yvbI	-	-	M	-	-	-	Membrane
NPEPGNMH_00306	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
NPEPGNMH_00307	2.4e-106	yvbK	-	-	K	-	-	-	acetyltransferase
NPEPGNMH_00308	1.38e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NPEPGNMH_00309	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
NPEPGNMH_00310	2.12e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NPEPGNMH_00311	1.97e-277	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
NPEPGNMH_00312	5.72e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NPEPGNMH_00313	4.22e-220	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NPEPGNMH_00314	0.0	araE	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NPEPGNMH_00315	1.51e-258	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
NPEPGNMH_00316	1.04e-245	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPEPGNMH_00317	3.45e-206	yvbU	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_00318	2.37e-199	yvbV	-	-	EG	-	-	-	EamA-like transporter family
NPEPGNMH_00319	7.07e-307	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
NPEPGNMH_00320	2.68e-252	-	-	-	S	-	-	-	Glycosyl hydrolase
NPEPGNMH_00321	1.45e-172	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NPEPGNMH_00322	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
NPEPGNMH_00323	4.61e-130	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NPEPGNMH_00324	7.53e-137	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPEPGNMH_00325	1.76e-257	yvfT	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NPEPGNMH_00326	2.48e-171	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
NPEPGNMH_00327	1.03e-209	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
NPEPGNMH_00328	7.25e-201	rsbQ	-	-	S	ko:K19707	-	ko00000,ko03021	Alpha/beta hydrolase family
NPEPGNMH_00329	1.52e-265	-	3.1.3.3	-	T	ko:K07315	-	ko00000,ko01000,ko03021	response regulator
NPEPGNMH_00330	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
NPEPGNMH_00331	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
NPEPGNMH_00332	3.82e-194	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
NPEPGNMH_00333	4.23e-155	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
NPEPGNMH_00334	3.65e-127	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
NPEPGNMH_00335	2.05e-295	cycB	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
NPEPGNMH_00336	6.42e-237	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
NPEPGNMH_00337	9.32e-145	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
NPEPGNMH_00338	8.21e-126	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
NPEPGNMH_00339	1.81e-238	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
NPEPGNMH_00340	2.56e-143	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NPEPGNMH_00341	1.46e-118	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NPEPGNMH_00342	5.69e-44	yvfG	-	-	S	-	-	-	YvfG protein
NPEPGNMH_00343	1.85e-241	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
NPEPGNMH_00344	1.2e-284	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
NPEPGNMH_00345	6.53e-81	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
NPEPGNMH_00346	1.65e-141	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NPEPGNMH_00347	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NPEPGNMH_00348	4.44e-251	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
NPEPGNMH_00349	5.09e-264	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
NPEPGNMH_00350	6.3e-251	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
NPEPGNMH_00351	8.82e-265	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
NPEPGNMH_00352	4.67e-280	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
NPEPGNMH_00353	2.16e-202	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
NPEPGNMH_00354	2.95e-286	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
NPEPGNMH_00355	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
NPEPGNMH_00356	7.94e-150	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
NPEPGNMH_00357	2.78e-158	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
NPEPGNMH_00358	2.15e-99	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
NPEPGNMH_00359	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
NPEPGNMH_00361	5.4e-120	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
NPEPGNMH_00362	5.1e-64	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
NPEPGNMH_00363	1.51e-163	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
NPEPGNMH_00364	0.0	pbpE	-	-	V	-	-	-	Beta-lactamase
NPEPGNMH_00365	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
NPEPGNMH_00366	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
NPEPGNMH_00367	0.0	ybeC	-	-	E	-	-	-	amino acid
NPEPGNMH_00368	1.17e-137	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_00369	6.31e-68	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
NPEPGNMH_00370	1.03e-66	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
NPEPGNMH_00371	5.53e-122	yvdQ	-	-	S	-	-	-	Protein of unknown function (DUF3231)
NPEPGNMH_00372	0.0	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
NPEPGNMH_00373	1.99e-235	-	-	-	S	-	-	-	Patatin-like phospholipase
NPEPGNMH_00375	8.17e-135	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NPEPGNMH_00376	1.01e-156	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
NPEPGNMH_00377	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
NPEPGNMH_00378	0.0	yvdK	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycoside hydrolase, family 65
NPEPGNMH_00379	2.42e-203	malA	-	-	S	-	-	-	Protein of unknown function (DUF1189)
NPEPGNMH_00380	1.18e-190	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
NPEPGNMH_00381	2.12e-311	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
NPEPGNMH_00382	1.03e-302	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
NPEPGNMH_00383	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
NPEPGNMH_00384	2.28e-223	yvdE	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_00385	2.66e-137	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
NPEPGNMH_00386	7.84e-71	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
NPEPGNMH_00387	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
NPEPGNMH_00388	3.73e-137	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
NPEPGNMH_00389	1.4e-235	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPEPGNMH_00390	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
NPEPGNMH_00391	4.46e-181	yxdL_2	-	-	V	ko:K02003,ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPGNMH_00392	1.68e-252	yvcQ	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
NPEPGNMH_00393	4.67e-172	yvcP	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPEPGNMH_00394	1.37e-45	-	-	-	-	-	-	-	-
NPEPGNMH_00395	5.24e-188	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
NPEPGNMH_00396	3.92e-50	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
NPEPGNMH_00397	3.63e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
NPEPGNMH_00398	6.72e-227	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
NPEPGNMH_00399	2.09e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
NPEPGNMH_00400	2.39e-117	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NPEPGNMH_00401	8.31e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NPEPGNMH_00402	3.05e-190	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
NPEPGNMH_00403	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
NPEPGNMH_00404	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
NPEPGNMH_00406	0.0	-	-	-	-	-	-	-	-
NPEPGNMH_00407	6.36e-172	-	-	-	-	-	-	-	-
NPEPGNMH_00408	2.61e-146	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
NPEPGNMH_00409	9.74e-177	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NPEPGNMH_00410	1.44e-170	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NPEPGNMH_00411	7.21e-150	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NPEPGNMH_00412	4.96e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
NPEPGNMH_00413	1.19e-297	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NPEPGNMH_00414	9.09e-149	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NPEPGNMH_00415	1.77e-250	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NPEPGNMH_00416	2.36e-08	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NPEPGNMH_00417	2.14e-179	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
NPEPGNMH_00418	5.68e-156	-	4.2.2.10, 4.2.2.2	-	G	ko:K19551	ko00040,map00040	ko00000,ko00001,ko01000	Pectate lyase
NPEPGNMH_00419	5.29e-121	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
NPEPGNMH_00420	4.51e-155	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
NPEPGNMH_00421	3.19e-212	yvoD	-	-	P	-	-	-	COG0370 Fe2 transport system protein B
NPEPGNMH_00422	3.18e-195	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NPEPGNMH_00423	3.62e-217	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NPEPGNMH_00424	2.25e-284	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NPEPGNMH_00425	1.39e-171	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NPEPGNMH_00426	5.23e-172	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
NPEPGNMH_00427	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
NPEPGNMH_00428	9.4e-110	yvnA	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NPEPGNMH_00429	1.61e-293	cypX	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
NPEPGNMH_00430	2.24e-127	yvmC	2.3.2.22	-	S	ko:K17485	-	ko00000,ko01000	Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
NPEPGNMH_00431	4.38e-83	yvmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NPEPGNMH_00432	1.68e-268	yvmA	-	-	EGP	-	-	-	Major Facilitator Superfamily
NPEPGNMH_00433	3.8e-66	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
NPEPGNMH_00434	1.5e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
NPEPGNMH_00435	5.8e-221	yvlB	-	-	S	-	-	-	Putative adhesin
NPEPGNMH_00436	8.09e-65	yvlA	-	-	-	-	-	-	-
NPEPGNMH_00437	2.73e-46	yvkN	-	-	-	-	-	-	-
NPEPGNMH_00438	2.57e-104	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NPEPGNMH_00439	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NPEPGNMH_00440	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NPEPGNMH_00441	2.54e-42	csbA	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_00442	1.55e-171	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
NPEPGNMH_00443	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
NPEPGNMH_00444	1.43e-131	yvkB	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_00445	5.47e-298	yvkA	-	-	P	-	-	-	-transporter
NPEPGNMH_00446	3.86e-281	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NPEPGNMH_00447	1.38e-73	swrA	-	-	S	-	-	-	Swarming motility protein
NPEPGNMH_00448	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
NPEPGNMH_00449	5.45e-199	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NPEPGNMH_00450	1.5e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
NPEPGNMH_00451	3.23e-75	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
NPEPGNMH_00452	6.5e-185	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
NPEPGNMH_00453	2e-232	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NPEPGNMH_00454	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NPEPGNMH_00455	1.73e-132	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NPEPGNMH_00456	9.14e-88	-	-	-	-	-	-	-	-
NPEPGNMH_00457	8.69e-09	fliT	-	-	S	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
NPEPGNMH_00458	5.15e-91	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
NPEPGNMH_00459	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NPEPGNMH_00460	1.1e-76	flaG	-	-	N	ko:K06603	-	ko00000,ko02035	flagellar protein FlaG
NPEPGNMH_00461	8.01e-202	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NPEPGNMH_00462	2.58e-41	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NPEPGNMH_00463	1.23e-96	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NPEPGNMH_00464	8.44e-73	yviE	-	-	-	-	-	-	-
NPEPGNMH_00465	8.83e-168	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
NPEPGNMH_00466	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
NPEPGNMH_00467	3.5e-102	yvyG	-	-	NOU	-	-	-	FlgN protein
NPEPGNMH_00468	1.06e-53	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
NPEPGNMH_00469	1.83e-96	yvyF	-	-	S	-	-	-	flagellar protein
NPEPGNMH_00470	9.99e-166	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
NPEPGNMH_00471	1.26e-61	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
NPEPGNMH_00472	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NPEPGNMH_00473	2.15e-199	degV	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_00474	7.16e-163	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPEPGNMH_00475	2.94e-247	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
NPEPGNMH_00476	2.41e-155	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
NPEPGNMH_00477	3.99e-225	yvhJ	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_00478	2.1e-231	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
NPEPGNMH_00479	3.3e-303	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
NPEPGNMH_00480	8.42e-187	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
NPEPGNMH_00481	4.51e-134	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
NPEPGNMH_00483	0.0	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
NPEPGNMH_00484	0.0	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NPEPGNMH_00485	8.77e-283	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
NPEPGNMH_00486	2.58e-316	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NPEPGNMH_00487	1.49e-143	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NPEPGNMH_00488	0.0	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
NPEPGNMH_00489	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
NPEPGNMH_00490	3.26e-50	-	-	-	-	-	-	-	-
NPEPGNMH_00491	2.77e-219	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
NPEPGNMH_00492	6.61e-278	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NPEPGNMH_00493	1.78e-208	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
NPEPGNMH_00494	0.0	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NPEPGNMH_00495	6.24e-140	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NPEPGNMH_00496	9.54e-93	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NPEPGNMH_00497	2.23e-67	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NPEPGNMH_00498	5.43e-05	-	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase-like
NPEPGNMH_00499	2.13e-127	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
NPEPGNMH_00500	0.0	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NPEPGNMH_00501	2.06e-194	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
NPEPGNMH_00502	0.0	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NPEPGNMH_00503	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferase 1 domain A
NPEPGNMH_00504	2.32e-55	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
NPEPGNMH_00505	3.69e-27	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
NPEPGNMH_00506	1.9e-185	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NPEPGNMH_00507	3.8e-273	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NPEPGNMH_00508	0.0	-	-	-	-	-	-	-	-
NPEPGNMH_00509	0.0	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NPEPGNMH_00510	1.16e-241	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
NPEPGNMH_00511	2.26e-47	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
NPEPGNMH_00512	2.39e-270	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
NPEPGNMH_00513	2.19e-33	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
NPEPGNMH_00514	1.81e-175	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
NPEPGNMH_00515	2.29e-275	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
NPEPGNMH_00516	8.19e-316	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NPEPGNMH_00517	1.48e-222	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_00518	7.24e-205	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
NPEPGNMH_00519	1.37e-304	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NPEPGNMH_00520	2.29e-29	ywtC	-	-	-	-	-	-	-
NPEPGNMH_00521	1.33e-277	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
NPEPGNMH_00522	8.44e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
NPEPGNMH_00523	1.46e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
NPEPGNMH_00524	2.3e-228	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
NPEPGNMH_00525	6.44e-207	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NPEPGNMH_00526	5.6e-85	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NPEPGNMH_00527	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NPEPGNMH_00528	2.87e-204	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NPEPGNMH_00529	1.34e-205	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
NPEPGNMH_00530	2.49e-122	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
NPEPGNMH_00531	9.2e-64	ywsA	-	-	S	-	-	-	Protein of unknown function (DUF3892)
NPEPGNMH_00532	2.15e-126	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
NPEPGNMH_00533	1.84e-187	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
NPEPGNMH_00534	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
NPEPGNMH_00535	3.36e-218	alsR	-	-	K	-	-	-	LysR substrate binding domain
NPEPGNMH_00536	5.98e-306	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NPEPGNMH_00537	9.09e-164	ywrJ	-	-	-	-	-	-	-
NPEPGNMH_00538	4.99e-147	cotB	-	-	-	ko:K06325	-	ko00000	-
NPEPGNMH_00539	5.41e-29	cotB	-	-	-	ko:K06325	-	ko00000	-
NPEPGNMH_00540	1.12e-269	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
NPEPGNMH_00541	1.81e-16	-	-	-	-	-	-	-	-
NPEPGNMH_00542	4.35e-143	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NPEPGNMH_00543	2.78e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF4181)
NPEPGNMH_00544	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
NPEPGNMH_00545	4.83e-108	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
NPEPGNMH_00546	5.52e-133	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
NPEPGNMH_00547	3.66e-115	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
NPEPGNMH_00549	3.83e-132	ywqN	-	-	S	-	-	-	NAD(P)H-dependent
NPEPGNMH_00550	1.16e-209	-	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_00551	7.78e-176	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
NPEPGNMH_00552	1.36e-71	-	-	-	S	-	-	-	MORN repeat variant
NPEPGNMH_00553	0.0	-	-	-	L	-	-	-	nucleic acid phosphodiester bond hydrolysis
NPEPGNMH_00554	2.17e-52	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
NPEPGNMH_00556	2.52e-197	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
NPEPGNMH_00557	9.82e-315	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NPEPGNMH_00558	3.16e-183	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
NPEPGNMH_00559	4.51e-156	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
NPEPGNMH_00560	5.33e-163	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
NPEPGNMH_00561	3.6e-25	-	-	-	-	-	-	-	-
NPEPGNMH_00562	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
NPEPGNMH_00563	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
NPEPGNMH_00564	4.53e-203	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
NPEPGNMH_00565	4.82e-180	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
NPEPGNMH_00566	1.04e-76	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
NPEPGNMH_00567	8.5e-43	ywpG	-	-	-	-	-	-	-
NPEPGNMH_00568	8.81e-89	ywpF	-	-	S	-	-	-	YwpF-like protein
NPEPGNMH_00569	4.63e-68	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
NPEPGNMH_00570	8.54e-198	ywpD	-	-	T	-	-	-	Histidine kinase
NPEPGNMH_00571	1.13e-79	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NPEPGNMH_00572	6.89e-107	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NPEPGNMH_00573	5.45e-257	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
NPEPGNMH_00574	4.1e-182	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
NPEPGNMH_00575	6.18e-173	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
NPEPGNMH_00576	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
NPEPGNMH_00577	4.88e-59	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
NPEPGNMH_00578	8.45e-92	-	-	-	K	-	-	-	COG1846 Transcriptional regulators
NPEPGNMH_00579	1.37e-269	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
NPEPGNMH_00580	1.02e-312	ywoF	-	-	P	-	-	-	Right handed beta helix region
NPEPGNMH_00581	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
NPEPGNMH_00582	8e-309	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
NPEPGNMH_00583	8.33e-76	yjgF	-	-	Q	-	-	-	Isochorismatase family
NPEPGNMH_00584	3.04e-102	-	-	-	-	-	-	-	-
NPEPGNMH_00585	1.6e-288	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
NPEPGNMH_00586	4.51e-77	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
NPEPGNMH_00587	6.02e-135	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
NPEPGNMH_00588	1.63e-95	ywnJ	-	-	S	-	-	-	VanZ like family
NPEPGNMH_00589	2.13e-175	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
NPEPGNMH_00590	1.55e-116	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
NPEPGNMH_00591	3.28e-22	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
NPEPGNMH_00592	7.07e-92	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
NPEPGNMH_00593	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPEPGNMH_00594	3.41e-184	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
NPEPGNMH_00595	1.06e-78	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
NPEPGNMH_00596	1.29e-148	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
NPEPGNMH_00597	4.58e-85	ywnA	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_00598	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NPEPGNMH_00599	1.12e-83	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
NPEPGNMH_00600	8.2e-68	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
NPEPGNMH_00602	1.11e-21	csbD	-	-	K	-	-	-	CsbD-like
NPEPGNMH_00603	1.12e-109	ywmF	-	-	S	-	-	-	Peptidase M50
NPEPGNMH_00604	1.25e-128	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
NPEPGNMH_00605	2.65e-246	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NPEPGNMH_00606	2.22e-187	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NPEPGNMH_00608	1.02e-155	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
NPEPGNMH_00609	1.89e-157	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
NPEPGNMH_00610	3.72e-238	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
NPEPGNMH_00611	4.96e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NPEPGNMH_00612	2.39e-174	ywmB	-	-	S	-	-	-	TATA-box binding
NPEPGNMH_00613	4.54e-45	ywzB	-	-	S	-	-	-	membrane
NPEPGNMH_00614	6.12e-115	ywmA	-	-	-	-	-	-	-
NPEPGNMH_00615	1.04e-76	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
NPEPGNMH_00616	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NPEPGNMH_00617	6.27e-165	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NPEPGNMH_00618	5.52e-217	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NPEPGNMH_00619	1.01e-104	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NPEPGNMH_00620	2.89e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NPEPGNMH_00621	2.62e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NPEPGNMH_00622	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NPEPGNMH_00623	6.06e-167	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
NPEPGNMH_00624	1.91e-81	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
NPEPGNMH_00625	5.5e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NPEPGNMH_00626	4.36e-303	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NPEPGNMH_00627	2.49e-123	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
NPEPGNMH_00628	2.35e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
NPEPGNMH_00629	5.75e-103	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NPEPGNMH_00630	4.56e-117	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
NPEPGNMH_00631	4.44e-252	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NPEPGNMH_00632	1.79e-100	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
NPEPGNMH_00633	1.14e-152	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
NPEPGNMH_00634	1.67e-74	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
NPEPGNMH_00636	5.96e-205	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NPEPGNMH_00637	9.95e-245	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NPEPGNMH_00638	1.19e-89	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPEPGNMH_00639	6.26e-119	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
NPEPGNMH_00640	3.24e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
NPEPGNMH_00641	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
NPEPGNMH_00642	8.53e-136	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
NPEPGNMH_00643	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
NPEPGNMH_00644	5.53e-303	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NPEPGNMH_00645	3.51e-225	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
NPEPGNMH_00646	2.26e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NPEPGNMH_00647	5.69e-147	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NPEPGNMH_00648	7.82e-204	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
NPEPGNMH_00649	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
NPEPGNMH_00650	3.31e-120	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
NPEPGNMH_00651	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NPEPGNMH_00652	1.03e-82	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NPEPGNMH_00653	2.1e-269	acdA	-	-	I	-	-	-	acyl-CoA dehydrogenase
NPEPGNMH_00654	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
NPEPGNMH_00655	8.56e-290	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NPEPGNMH_00656	4.88e-236	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
NPEPGNMH_00657	1.32e-57	ywjC	-	-	-	-	-	-	-
NPEPGNMH_00658	1.35e-124	ywjB	-	-	H	-	-	-	RibD C-terminal domain
NPEPGNMH_00659	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
NPEPGNMH_00660	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPEPGNMH_00661	1.02e-159	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
NPEPGNMH_00662	6.32e-128	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
NPEPGNMH_00663	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
NPEPGNMH_00664	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NPEPGNMH_00665	8.67e-111	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
NPEPGNMH_00666	1.57e-180	ywiC	-	-	S	-	-	-	YwiC-like protein
NPEPGNMH_00667	3.98e-169	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
NPEPGNMH_00668	3.39e-274	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
NPEPGNMH_00669	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
NPEPGNMH_00670	4.64e-96	ywiB	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_00671	3.71e-12	-	-	-	S	-	-	-	Bacteriocin subtilosin A
NPEPGNMH_00672	0.0	-	-	-	C	ko:K22227	-	ko00000	Fe-S oxidoreductases
NPEPGNMH_00674	1.5e-169	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NPEPGNMH_00675	1.07e-300	mgtA	3.6.3.2	-	P	ko:K01531,ko:K16905	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase, P-type transporting, HAD superfamily, subfamily IC
NPEPGNMH_00676	7.55e-280	-	2.7.1.26, 2.7.7.2	-	L	ko:K07263,ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase, M16
NPEPGNMH_00677	0.0	-	-	-	L	-	-	-	Peptidase, M16
NPEPGNMH_00679	0.0	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
NPEPGNMH_00680	2.36e-291	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
NPEPGNMH_00681	2.88e-100	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
NPEPGNMH_00683	6.61e-110	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
NPEPGNMH_00684	2.1e-215	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
NPEPGNMH_00685	1.93e-204	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NPEPGNMH_00686	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
NPEPGNMH_00687	1.92e-123	ywhD	-	-	S	-	-	-	YwhD family
NPEPGNMH_00688	3.29e-154	ywhC	-	-	S	-	-	-	Peptidase family M50
NPEPGNMH_00689	1.43e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
NPEPGNMH_00690	1.76e-94	ywhA	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_00691	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NPEPGNMH_00693	2.66e-307	mmr	-	-	U	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
NPEPGNMH_00694	1.1e-103	yffB	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_00695	1.47e-115	ywgA	-	-	-	ko:K09388	-	ko00000	-
NPEPGNMH_00696	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
NPEPGNMH_00697	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
NPEPGNMH_00698	5.65e-147	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
NPEPGNMH_00699	1.57e-204	ywfM	-	-	EG	ko:K03298	-	ko00000,ko02000	EamA-like transporter family
NPEPGNMH_00700	2.15e-199	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
NPEPGNMH_00701	9.56e-212	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
NPEPGNMH_00702	7.1e-226	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
NPEPGNMH_00703	3.43e-187	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
NPEPGNMH_00704	3.52e-178	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
NPEPGNMH_00705	1.89e-298	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
NPEPGNMH_00706	1.36e-268	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
NPEPGNMH_00707	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
NPEPGNMH_00708	1.33e-179	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPEPGNMH_00709	1.24e-175	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
NPEPGNMH_00710	5.11e-146	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
NPEPGNMH_00711	1.89e-275	ywfA	-	-	EGP	-	-	-	-transporter
NPEPGNMH_00712	0.0	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
NPEPGNMH_00713	4.67e-314	rocB	-	-	E	-	-	-	arginine degradation protein
NPEPGNMH_00714	5.75e-41	rocB	-	-	E	-	-	-	arginine degradation protein
NPEPGNMH_00715	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
NPEPGNMH_00716	5.19e-311	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
NPEPGNMH_00717	1.1e-102	-	-	-	-	-	-	-	-
NPEPGNMH_00718	9.16e-114	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
NPEPGNMH_00719	2.44e-206	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NPEPGNMH_00720	2.5e-25	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NPEPGNMH_00721	1.71e-194	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NPEPGNMH_00722	2.6e-178	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NPEPGNMH_00723	2.54e-243	spsG	-	-	M	-	-	-	Spore Coat
NPEPGNMH_00724	4.64e-169	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
NPEPGNMH_00725	6.8e-272	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
NPEPGNMH_00726	1.04e-210	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
NPEPGNMH_00727	4.54e-285	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
NPEPGNMH_00728	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
NPEPGNMH_00729	4.87e-188	spsA	-	-	M	-	-	-	Spore Coat
NPEPGNMH_00730	7.61e-114	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
NPEPGNMH_00731	1.59e-78	ywdK	-	-	S	-	-	-	small membrane protein
NPEPGNMH_00732	4.57e-304	ywdJ	-	-	F	-	-	-	Xanthine uracil
NPEPGNMH_00733	9.23e-65	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
NPEPGNMH_00734	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
NPEPGNMH_00735	2.32e-166	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NPEPGNMH_00736	5.69e-193	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
NPEPGNMH_00738	8.74e-146	ywdD	-	-	-	-	-	-	-
NPEPGNMH_00739	7.92e-76	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
NPEPGNMH_00740	5.43e-188	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NPEPGNMH_00741	6.19e-39	ywdA	-	-	-	-	-	-	-
NPEPGNMH_00742	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
NPEPGNMH_00743	0.0	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NPEPGNMH_00744	2.91e-180	-	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
NPEPGNMH_00745	4.49e-194	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
NPEPGNMH_00747	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
NPEPGNMH_00748	4.19e-239	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPEPGNMH_00749	1.98e-179	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
NPEPGNMH_00750	8.89e-269	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
NPEPGNMH_00751	6.61e-52	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
NPEPGNMH_00752	1.12e-83	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
NPEPGNMH_00753	1.2e-144	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
NPEPGNMH_00754	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NPEPGNMH_00755	6.94e-226	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
NPEPGNMH_00756	5.11e-49	ydaS	-	-	S	-	-	-	membrane
NPEPGNMH_00757	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
NPEPGNMH_00758	5.56e-291	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NPEPGNMH_00759	3.33e-77	gtcA	-	-	S	-	-	-	GtrA-like protein
NPEPGNMH_00760	2.19e-95	ywcC	-	-	K	-	-	-	transcriptional regulator
NPEPGNMH_00761	6.47e-42	ywcC	-	-	K	-	-	-	transcriptional regulator
NPEPGNMH_00763	7.41e-65	ywcB	-	-	S	-	-	-	Protein of unknown function, DUF485
NPEPGNMH_00764	0.0	ywcA	-	-	S	ko:K14393	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NPEPGNMH_00765	1.08e-145	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
NPEPGNMH_00766	3.23e-310	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
NPEPGNMH_00767	6.21e-249	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
NPEPGNMH_00768	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
NPEPGNMH_00769	7.69e-150	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NPEPGNMH_00770	3.25e-185	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NPEPGNMH_00771	2.7e-203	ywbI	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_00772	1.1e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
NPEPGNMH_00773	1.21e-143	ywbG	-	-	M	-	-	-	effector of murein hydrolase
NPEPGNMH_00774	1.29e-280	ywbF	-	-	EGP	ko:K05820	-	ko00000,ko02000	Nucleoside H+ symporter
NPEPGNMH_00775	1.32e-39	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
NPEPGNMH_00776	1.3e-283	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
NPEPGNMH_00777	1.99e-87	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
NPEPGNMH_00778	7.78e-165	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
NPEPGNMH_00779	1.02e-139	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPEPGNMH_00780	2.43e-153	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPEPGNMH_00781	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
NPEPGNMH_00782	1.45e-312	sacX	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NPEPGNMH_00783	9.07e-196	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
NPEPGNMH_00784	6.53e-217	gspA	-	-	M	-	-	-	General stress
NPEPGNMH_00785	5.97e-143	ywaF	-	-	S	-	-	-	Integral membrane protein
NPEPGNMH_00786	2.15e-115	ywaE	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_00787	2.7e-298	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NPEPGNMH_00788	0.0	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
NPEPGNMH_00789	2.52e-149	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
NPEPGNMH_00790	5.1e-213	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
NPEPGNMH_00791	1.27e-20	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
NPEPGNMH_00792	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPEPGNMH_00793	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
NPEPGNMH_00794	6.83e-50	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPEPGNMH_00795	4.54e-231	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NPEPGNMH_00796	2.91e-178	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
NPEPGNMH_00797	1.07e-263	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
NPEPGNMH_00798	0.0	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NPEPGNMH_00799	1.58e-50	licA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NPEPGNMH_00800	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPEPGNMH_00801	1.89e-67	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
NPEPGNMH_00802	1.16e-75	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
NPEPGNMH_00803	3.53e-281	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
NPEPGNMH_00804	8.94e-28	yxzF	-	-	-	-	-	-	-
NPEPGNMH_00805	3.23e-145	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
NPEPGNMH_00806	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
NPEPGNMH_00807	1.57e-257	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
NPEPGNMH_00808	3.96e-179	yxlG	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NPEPGNMH_00809	2.09e-213	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPGNMH_00810	2.17e-39	yxlE	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
NPEPGNMH_00811	1.75e-43	-	-	-	-	-	-	-	-
NPEPGNMH_00812	4.05e-64	yxlC	-	-	S	-	-	-	Family of unknown function (DUF5345)
NPEPGNMH_00813	9.06e-125	sigY	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NPEPGNMH_00814	0.0	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
NPEPGNMH_00815	2.01e-206	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NPEPGNMH_00816	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
NPEPGNMH_00817	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
NPEPGNMH_00818	1.16e-243	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
NPEPGNMH_00819	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
NPEPGNMH_00820	3.97e-310	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
NPEPGNMH_00821	0.0	-	-	-	O	-	-	-	Peptidase family M48
NPEPGNMH_00823	1.58e-200	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
NPEPGNMH_00824	3.44e-261	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NPEPGNMH_00825	1.16e-211	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
NPEPGNMH_00826	0.0	aldY	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NPEPGNMH_00827	2.29e-188	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NPEPGNMH_00828	1.66e-98	yxkC	-	-	S	-	-	-	Domain of unknown function (DUF4352)
NPEPGNMH_00829	2.11e-251	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
NPEPGNMH_00830	2.01e-123	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
NPEPGNMH_00831	1.53e-213	-	-	-	K	-	-	-	LysR substrate binding domain
NPEPGNMH_00832	5.63e-102	-	-	-	S	-	-	-	Protein of unknown function (DUF1453)
NPEPGNMH_00833	7.13e-261	-	-	-	T	-	-	-	Signal transduction histidine kinase
NPEPGNMH_00834	5.66e-150	-	-	-	K	ko:K02479	-	ko00000,ko02022	helix_turn_helix, Lux Regulon
NPEPGNMH_00835	7.76e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
NPEPGNMH_00838	2.57e-114	yxjI	-	-	S	-	-	-	LURP-one-related
NPEPGNMH_00839	7.74e-280	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
NPEPGNMH_00840	9.77e-279	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
NPEPGNMH_00841	5.83e-176	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NPEPGNMH_00842	5.91e-151	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NPEPGNMH_00843	4.65e-168	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NPEPGNMH_00844	6.29e-288	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
NPEPGNMH_00845	5.86e-20	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
NPEPGNMH_00846	4.55e-206	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
NPEPGNMH_00847	2.1e-269	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NPEPGNMH_00848	2.96e-29	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
NPEPGNMH_00849	9.65e-65	yxiS	-	-	-	-	-	-	-
NPEPGNMH_00850	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
NPEPGNMH_00851	2e-284	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
NPEPGNMH_00852	2.62e-185	bglS	-	-	M	-	-	-	licheninase activity
NPEPGNMH_00853	5.66e-193	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
NPEPGNMH_00854	2.75e-145	-	-	-	-	-	-	-	-
NPEPGNMH_00855	3.97e-294	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
NPEPGNMH_00856	1.45e-60	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
NPEPGNMH_00857	5.37e-110	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
NPEPGNMH_00858	3.28e-279	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NPEPGNMH_00861	5.53e-65	yxiJ	-	-	S	-	-	-	YxiJ-like protein
NPEPGNMH_00862	3.79e-125	yxiI	-	-	S	-	-	-	Protein of unknown function (DUF2716)
NPEPGNMH_00863	6.22e-107	-	-	-	-	-	-	-	-
NPEPGNMH_00864	1.2e-57	-	-	-	-	-	-	-	-
NPEPGNMH_00865	8.76e-99	yxiG	-	-	-	-	-	-	-
NPEPGNMH_00866	1.12e-82	-	-	-	-	-	-	-	-
NPEPGNMH_00867	3.69e-111	-	-	-	-	-	-	-	-
NPEPGNMH_00868	1.09e-94	yxxG	-	-	-	-	-	-	-
NPEPGNMH_00869	0.0	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
NPEPGNMH_00870	0.0	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
NPEPGNMH_00871	1.17e-216	yxxF	-	-	EG	-	-	-	EamA-like transporter family
NPEPGNMH_00872	8.5e-95	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
NPEPGNMH_00873	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NPEPGNMH_00874	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NPEPGNMH_00875	1.33e-67	-	-	-	-	-	-	-	-
NPEPGNMH_00876	0.0	-	-	-	S	ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
NPEPGNMH_00877	2.3e-53	yxiC	-	-	S	-	-	-	Family of unknown function (DUF5344)
NPEPGNMH_00878	1.88e-37	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
NPEPGNMH_00879	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
NPEPGNMH_00880	7.02e-103	hutP	-	-	K	ko:K09683	-	ko00000,ko03000	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
NPEPGNMH_00881	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
NPEPGNMH_00882	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NPEPGNMH_00883	2.44e-303	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
NPEPGNMH_00884	4.15e-232	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
NPEPGNMH_00885	0.0	ybgF	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
NPEPGNMH_00886	4.9e-300	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
NPEPGNMH_00887	1.92e-263	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NPEPGNMH_00888	1.44e-150	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NPEPGNMH_00889	4.26e-222	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NPEPGNMH_00890	4.12e-145	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1206)
NPEPGNMH_00891	4.86e-259	eutH	-	-	E	ko:K04023	-	ko00000	Ethanolamine utilisation protein, EutH
NPEPGNMH_00892	0.0	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
NPEPGNMH_00893	5.21e-275	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
NPEPGNMH_00894	1.67e-171	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NPEPGNMH_00895	1.81e-149	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
NPEPGNMH_00896	4.3e-186	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
NPEPGNMH_00897	1.54e-121	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPEPGNMH_00898	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPEPGNMH_00900	2.17e-243	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
NPEPGNMH_00901	1.4e-194	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
NPEPGNMH_00904	7.32e-42	yxeE	-	-	-	-	-	-	-
NPEPGNMH_00905	2.66e-28	yxeD	-	-	-	-	-	-	-
NPEPGNMH_00906	6.79e-91	-	-	-	-	-	-	-	-
NPEPGNMH_00907	9.01e-228	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NPEPGNMH_00908	5.95e-77	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
NPEPGNMH_00909	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
NPEPGNMH_00910	9.39e-182	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPGNMH_00911	4e-233	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NPEPGNMH_00912	2.8e-160	yxdJ	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPEPGNMH_00913	2.43e-205	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
NPEPGNMH_00914	9.32e-188	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
NPEPGNMH_00915	1.87e-213	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
NPEPGNMH_00916	1.55e-251	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NPEPGNMH_00917	1.46e-298	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
NPEPGNMH_00918	4.27e-223	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NPEPGNMH_00919	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NPEPGNMH_00920	2.13e-228	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NPEPGNMH_00921	1.46e-201	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NPEPGNMH_00922	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NPEPGNMH_00923	1.56e-177	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
NPEPGNMH_00924	1.74e-224	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
NPEPGNMH_00926	2.13e-64	yxcD	-	-	S	-	-	-	Protein of unknown function (DUF2653)
NPEPGNMH_00927	1.77e-314	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NPEPGNMH_00928	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
NPEPGNMH_00930	4.33e-195	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
NPEPGNMH_00931	7.14e-17	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NPEPGNMH_00932	4.35e-234	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NPEPGNMH_00933	1.21e-315	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
NPEPGNMH_00934	6.59e-111	yxbD	3.2.2.20	-	K	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Acetyltransferase (GNAT) domain
NPEPGNMH_00935	1.16e-239	-	-	-	S	-	-	-	A domain family that is part of the cupin metalloenzyme superfamily.
NPEPGNMH_00936	1.29e-177	yxbB	-	-	Q	-	-	-	Met-10+ like-protein
NPEPGNMH_00937	3.65e-59	-	-	-	S	-	-	-	Coenzyme PQQ synthesis protein D (PqqD)
NPEPGNMH_00938	8.99e-114	yxnB	-	-	-	-	-	-	-
NPEPGNMH_00939	0.0	-	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
NPEPGNMH_00940	1.8e-271	yxaM	-	-	U	-	-	-	MFS_1 like family
NPEPGNMH_00941	2.63e-137	yxaL	-	-	S	-	-	-	PQQ-like domain
NPEPGNMH_00942	1.43e-85	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
NPEPGNMH_00943	2.83e-99	yxaI	-	-	S	-	-	-	membrane protein domain
NPEPGNMH_00944	2.88e-290	-	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
NPEPGNMH_00945	9.33e-254	-	1.13.11.24	-	S	ko:K07155	-	ko00000,ko01000	AraC-like ligand binding domain
NPEPGNMH_00946	9.61e-131	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
NPEPGNMH_00947	4.48e-257	yxnA	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
NPEPGNMH_00948	6.83e-94	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NPEPGNMH_00949	2.53e-78	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
NPEPGNMH_00950	2.19e-153	yxaC	-	-	M	-	-	-	effector of murein hydrolase
NPEPGNMH_00951	1.79e-245	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
NPEPGNMH_00952	2.54e-267	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
NPEPGNMH_00953	4.42e-164	gntR	-	-	K	ko:K11476	-	ko00000,ko03000	transcriptional
NPEPGNMH_00954	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
NPEPGNMH_00955	8.05e-155	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
NPEPGNMH_00956	8.04e-105	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
NPEPGNMH_00957	0.0	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NPEPGNMH_00958	9.33e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
NPEPGNMH_00959	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
NPEPGNMH_00960	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NPEPGNMH_00961	6.69e-47	-	2.7.1.199	-	G	ko:K02777,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
NPEPGNMH_00962	6.34e-165	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
NPEPGNMH_00963	1.44e-24	-	-	-	-	-	-	-	-
NPEPGNMH_00964	4.04e-154	-	-	-	S	ko:K16916	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
NPEPGNMH_00965	5.06e-144	-	-	-	P	ko:K16917	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NPEPGNMH_00966	1.55e-173	-	-	-	O	ko:K16922	-	ko00000,ko01002	Peptidase M50
NPEPGNMH_00967	1.35e-237	-	-	-	S	-	-	-	Radical SAM superfamily
NPEPGNMH_00968	1.99e-17	-	-	-	-	-	-	-	-
NPEPGNMH_00969	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
NPEPGNMH_00970	0.0	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2326)
NPEPGNMH_00971	7.17e-86	-	-	-	-	-	-	-	-
NPEPGNMH_00972	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NPEPGNMH_00973	1.23e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NPEPGNMH_00975	1.25e-93	-	-	-	-	-	-	-	-
NPEPGNMH_00976	1.81e-297	yycR	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NPEPGNMH_00978	1.7e-45	yycQ	-	-	S	-	-	-	Protein of unknown function (DUF2651)
NPEPGNMH_00979	1.13e-72	yycP	-	-	-	-	-	-	-
NPEPGNMH_00980	8.47e-178	yycP	-	-	-	-	-	-	-
NPEPGNMH_00981	1.68e-169	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NPEPGNMH_00982	3.84e-113	yycN	-	-	K	-	-	-	Acetyltransferase
NPEPGNMH_00983	3.03e-239	-	-	-	S	-	-	-	aspartate phosphatase
NPEPGNMH_00985	3.22e-213	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
NPEPGNMH_00986	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
NPEPGNMH_00987	1.5e-296	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
NPEPGNMH_00988	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
NPEPGNMH_00989	2.42e-281	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NPEPGNMH_00990	4.01e-191	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
NPEPGNMH_00991	1.2e-200	yycI	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_00992	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_00993	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NPEPGNMH_00994	1.45e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPEPGNMH_00999	6.38e-315	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NPEPGNMH_01000	1.19e-101	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPEPGNMH_01001	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
NPEPGNMH_01002	3.48e-40	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
NPEPGNMH_01004	1.89e-22	yycC	-	-	K	-	-	-	YycC-like protein
NPEPGNMH_01005	4.19e-283	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
NPEPGNMH_01006	9.96e-25	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NPEPGNMH_01007	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NPEPGNMH_01008	2.74e-96	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
NPEPGNMH_01009	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
NPEPGNMH_01010	5.23e-205	yybS	-	-	S	-	-	-	membrane
NPEPGNMH_01012	2.89e-110	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
NPEPGNMH_01013	6.68e-90	yybR	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_01014	4.89e-210	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
NPEPGNMH_01015	2.34e-92	-	-	-	-	-	-	-	-
NPEPGNMH_01017	6.8e-308	yybO	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
NPEPGNMH_01018	3.44e-22	-	-	-	-	-	-	-	-
NPEPGNMH_01019	1.61e-102	yybN	-	-	S	-	-	-	Protein of unknown function (DUF2712)
NPEPGNMH_01020	3.78e-169	-	-	-	-	-	-	-	-
NPEPGNMH_01021	5.36e-157	-	-	-	-	-	-	-	-
NPEPGNMH_01022	2.34e-163	-	-	-	S	-	-	-	Protein of unknown function (DUF2705)
NPEPGNMH_01023	1.56e-118	yybJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NPEPGNMH_01024	4.35e-194	-	-	-	-	-	-	-	-
NPEPGNMH_01025	3.02e-88	-	-	-	S	-	-	-	SnoaL-like domain
NPEPGNMH_01026	1.46e-164	yybG	-	-	S	-	-	-	Pentapeptide repeat-containing protein
NPEPGNMH_01027	3.31e-281	yybF	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
NPEPGNMH_01028	1.36e-212	yybE	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_01029	7.91e-104	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
NPEPGNMH_01030	1.27e-99	yybC	-	-	-	-	-	-	-
NPEPGNMH_01031	5.29e-165	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
NPEPGNMH_01032	4.54e-100	yybA	-	-	K	-	-	-	transcriptional
NPEPGNMH_01033	2.45e-103	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
NPEPGNMH_01034	8.73e-132	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
NPEPGNMH_01035	4.03e-130	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
NPEPGNMH_01036	1.09e-87	-	-	-	S	-	-	-	YjbR
NPEPGNMH_01037	2.2e-139	yyaP	-	-	H	-	-	-	RibD C-terminal domain
NPEPGNMH_01038	0.0	tetL	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	COG0477 Permeases of the major facilitator superfamily
NPEPGNMH_01039	1.46e-58	yyaL	-	-	O	ko:K06888	-	ko00000	Highly conserved protein containing a thioredoxin domain
NPEPGNMH_01040	1.34e-88	-	-	-	K	-	-	-	MerR HTH family regulatory protein
NPEPGNMH_01041	1.99e-207	-	-	-	EG	-	-	-	EamA-like transporter family
NPEPGNMH_01042	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
NPEPGNMH_01043	8.91e-217	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NPEPGNMH_01044	0.0	-	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major facilitator superfamily
NPEPGNMH_01045	1.14e-130	vatD	2.3.1.28, 2.3.1.79	-	S	ko:K00638,ko:K00661,ko:K18234	-	br01600,ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
NPEPGNMH_01046	7.2e-90	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPEPGNMH_01047	3.03e-230	ccpB	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_01048	2.07e-187	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
NPEPGNMH_01049	4.25e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NPEPGNMH_01050	1.81e-103	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NPEPGNMH_01051	1.01e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
NPEPGNMH_01052	5.65e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NPEPGNMH_01053	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NPEPGNMH_01054	7.41e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_01055	5.34e-227	yyaD	-	-	S	-	-	-	Membrane
NPEPGNMH_01056	9.15e-145	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
NPEPGNMH_01057	3.96e-191	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NPEPGNMH_01058	4.79e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
NPEPGNMH_01059	1.13e-98	-	-	-	S	-	-	-	Bacterial PH domain
NPEPGNMH_01060	9e-193	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
NPEPGNMH_01061	8.68e-169	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
NPEPGNMH_01062	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NPEPGNMH_01063	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NPEPGNMH_01064	1.83e-141	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
NPEPGNMH_01065	1.23e-169	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NPEPGNMH_01066	5.7e-71	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NPEPGNMH_01067	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NPEPGNMH_01068	1.71e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NPEPGNMH_01069	2.24e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
NPEPGNMH_01070	4.54e-264	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NPEPGNMH_01071	1.25e-51	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
NPEPGNMH_01072	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NPEPGNMH_01073	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NPEPGNMH_01074	2.97e-150	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPEPGNMH_01075	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPEPGNMH_01076	0.0	-	6.3.2.14	-	Q	ko:K02364,ko:K15656,ko:K15668	ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024	ko00000,ko00001,ko01000,ko01008	amino acid activation for nonribosomal peptide biosynthetic process
NPEPGNMH_01077	2.12e-84	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
NPEPGNMH_01078	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
NPEPGNMH_01080	4.3e-41	-	-	-	S	-	-	-	Family of unknown function (DUF5367)
NPEPGNMH_01081	1.31e-268	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
NPEPGNMH_01082	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NPEPGNMH_01083	0.0	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
NPEPGNMH_01084	1.23e-43	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
NPEPGNMH_01085	7.02e-214	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
NPEPGNMH_01086	1.48e-175	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
NPEPGNMH_01087	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NPEPGNMH_01088	4.46e-297	yngD	-	-	S	ko:K07097	-	ko00000	phosphohydrolase (DHH superfamily)
NPEPGNMH_01089	2.01e-134	yngC	-	-	S	-	-	-	membrane-associated protein
NPEPGNMH_01090	2.74e-210	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
NPEPGNMH_01091	1.04e-104	yngA	-	-	S	-	-	-	membrane
NPEPGNMH_01092	0.0	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
NPEPGNMH_01093	0.0	ynfF	3.2.1.136	GH5	M	ko:K15924	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 30 family
NPEPGNMH_01095	0.0	bglC5	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 5
NPEPGNMH_01096	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
NPEPGNMH_01097	1.06e-75	ynfC	-	-	-	-	-	-	-
NPEPGNMH_01098	1.82e-18	-	-	-	-	-	-	-	-
NPEPGNMH_01099	2.17e-223	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NPEPGNMH_01100	8.09e-282	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NPEPGNMH_01101	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NPEPGNMH_01102	1.21e-90	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
NPEPGNMH_01103	5.48e-122	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NPEPGNMH_01104	8.97e-65	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
NPEPGNMH_01105	1.63e-71	yneQ	-	-	-	-	-	-	-
NPEPGNMH_01106	1.4e-95	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
NPEPGNMH_01107	6.62e-48	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
NPEPGNMH_01109	9.26e-10	-	-	-	S	-	-	-	Fur-regulated basic protein B
NPEPGNMH_01110	3.74e-120	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NPEPGNMH_01111	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NPEPGNMH_01112	3.75e-21	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
NPEPGNMH_01113	5.65e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
NPEPGNMH_01114	1.21e-86	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
NPEPGNMH_01115	2.79e-97	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
NPEPGNMH_01116	2.51e-98	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
NPEPGNMH_01117	7.38e-78	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
NPEPGNMH_01118	4.13e-165	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
NPEPGNMH_01119	4.36e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
NPEPGNMH_01120	2.18e-106	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
NPEPGNMH_01121	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NPEPGNMH_01122	1.15e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
NPEPGNMH_01123	3.97e-145	yneB	-	-	L	-	-	-	resolvase
NPEPGNMH_01124	8.5e-65	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
NPEPGNMH_01125	7.22e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NPEPGNMH_01127	4.44e-104	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
NPEPGNMH_01128	7.41e-120	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
NPEPGNMH_01129	1.68e-177	yndL	-	-	S	-	-	-	Replication protein
NPEPGNMH_01131	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
NPEPGNMH_01132	1.26e-151	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
NPEPGNMH_01133	9.15e-199	yndG	-	-	S	-	-	-	DoxX-like family
NPEPGNMH_01134	1.1e-242	-	-	-	S	ko:K06293,ko:K06312	-	ko00000	Spore germination protein
NPEPGNMH_01135	2.38e-251	yndE7	-	-	U	ko:K06311	-	ko00000,ko02000	Spore germination
NPEPGNMH_01136	0.0	yndD1	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
NPEPGNMH_01139	3.12e-104	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
NPEPGNMH_01140	8.92e-96	-	-	-	-	-	-	-	-
NPEPGNMH_01141	2.37e-34	tatA	-	-	U	ko:K03116,ko:K03117,ko:K03646	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02000,ko02044	protein secretion
NPEPGNMH_01144	1.55e-172	-	-	-	S	-	-	-	Domain of unknown function, YrpD
NPEPGNMH_01146	7.03e-213	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NPEPGNMH_01149	7.54e-22	-	-	-	-	-	-	-	-
NPEPGNMH_01150	3.01e-102	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
NPEPGNMH_01151	3.44e-110	-	-	-	S	-	-	-	Protein of unknown function (DUF2691)
NPEPGNMH_01152	3.05e-281	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NPEPGNMH_01153	3.64e-313	-	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NPEPGNMH_01154	9.1e-148	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
NPEPGNMH_01155	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
NPEPGNMH_01156	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
NPEPGNMH_01157	3.15e-278	xylR	-	-	GK	-	-	-	ROK family
NPEPGNMH_01158	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
NPEPGNMH_01159	0.0	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
NPEPGNMH_01160	1.34e-56	-	-	-	E	-	-	-	phosphoribosylanthranilate isomerase activity
NPEPGNMH_01161	3.36e-36	-	-	-	E	-	-	-	phosphoribosylanthranilate isomerase activity
NPEPGNMH_01164	1.06e-80	ynaF	-	-	-	-	-	-	-
NPEPGNMH_01165	1.65e-160	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
NPEPGNMH_01166	7.56e-129	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NPEPGNMH_01167	1.97e-186	ynaC	-	-	-	-	-	-	-
NPEPGNMH_01168	5.4e-105	-	-	-	G	-	-	-	regulation of fungal-type cell wall biogenesis
NPEPGNMH_01169	7.13e-52	-	-	-	-	-	-	-	-
NPEPGNMH_01170	2.61e-40	-	-	-	-	-	-	-	-
NPEPGNMH_01171	2.95e-14	-	-	-	-	-	-	-	-
NPEPGNMH_01172	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
NPEPGNMH_01173	9.94e-90	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
NPEPGNMH_01174	5.82e-311	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
NPEPGNMH_01175	4.47e-294	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NPEPGNMH_01176	2.29e-226	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
NPEPGNMH_01177	1.72e-151	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
NPEPGNMH_01178	2.24e-141	-	-	-	-	-	-	-	-
NPEPGNMH_01179	1.65e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPEPGNMH_01180	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPEPGNMH_01181	5.01e-66	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
NPEPGNMH_01182	1.17e-30	ymzA	-	-	-	-	-	-	-
NPEPGNMH_01183	8.07e-32	-	-	-	-	-	-	-	-
NPEPGNMH_01184	1.28e-45	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
NPEPGNMH_01185	1.17e-214	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NPEPGNMH_01186	5.41e-76	ymaF	-	-	S	-	-	-	YmaF family
NPEPGNMH_01188	1.21e-67	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
NPEPGNMH_01189	1.57e-73	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	COG2076 Membrane transporters of cations and cationic drugs
NPEPGNMH_01190	1.03e-105	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
NPEPGNMH_01191	3.96e-163	ymaC	-	-	S	-	-	-	Replication protein
NPEPGNMH_01192	2.62e-30	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
NPEPGNMH_01193	7.04e-284	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
NPEPGNMH_01194	4.8e-210	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
NPEPGNMH_01195	2.8e-81	ymzB	-	-	-	-	-	-	-
NPEPGNMH_01196	2.49e-297	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
NPEPGNMH_01197	0.0	-	-	-	HQ	ko:K13615	-	ko00000,ko01004,ko01008	Beta-ketoacyl synthase
NPEPGNMH_01198	1.35e-171	-	-	-	HQ	ko:K13615	-	ko00000,ko01004,ko01008	Beta-ketoacyl synthase
NPEPGNMH_01199	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
NPEPGNMH_01200	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
NPEPGNMH_01201	0.0	-	-	-	Q	ko:K13612	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
NPEPGNMH_01202	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
NPEPGNMH_01203	2.69e-177	pksI	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
NPEPGNMH_01204	2.48e-184	-	-	-	I	ko:K15312	-	ko00000,ko01008	enoyl-CoA hydratase
NPEPGNMH_01205	9.7e-314	pksG	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
NPEPGNMH_01206	5.31e-304	-	2.3.1.179	-	I	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NPEPGNMH_01207	5.46e-51	acpK	-	-	IQ	ko:K15337	-	ko00000,ko01008	Phosphopantetheine attachment site
NPEPGNMH_01208	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
NPEPGNMH_01209	2.08e-239	pksD	-	-	Q	ko:K15328	-	ko00000,ko01008	Acyl transferase domain
NPEPGNMH_01211	1.31e-208	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
NPEPGNMH_01212	4.02e-167	pksB	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	Polyketide biosynthesis
NPEPGNMH_01213	2.94e-141	pksA	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_01214	1.38e-127	ymcC	-	-	S	-	-	-	Membrane
NPEPGNMH_01216	7.19e-93	-	-	-	S	-	-	-	Regulatory protein YrvL
NPEPGNMH_01217	3.19e-164	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NPEPGNMH_01218	2.73e-248	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NPEPGNMH_01219	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NPEPGNMH_01220	1.74e-119	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
NPEPGNMH_01221	1.27e-89	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
NPEPGNMH_01222	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NPEPGNMH_01223	1.02e-278	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NPEPGNMH_01224	3.02e-255	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
NPEPGNMH_01225	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
NPEPGNMH_01226	3.2e-88	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
NPEPGNMH_01227	6.71e-93	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
NPEPGNMH_01228	4.25e-306	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
NPEPGNMH_01229	8.43e-282	pbpX	-	-	V	-	-	-	Beta-lactamase
NPEPGNMH_01230	4.7e-239	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NPEPGNMH_01231	3.71e-300	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
NPEPGNMH_01232	3.34e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NPEPGNMH_01233	1.34e-39	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
NPEPGNMH_01234	2e-98	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
NPEPGNMH_01235	4.57e-182	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
NPEPGNMH_01236	5.13e-55	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
NPEPGNMH_01237	6.33e-168	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NPEPGNMH_01238	2.37e-309	ymfH	-	-	S	-	-	-	zinc protease
NPEPGNMH_01239	2.96e-302	albE	-	-	S	-	-	-	Peptidase M16
NPEPGNMH_01240	2.08e-267	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
NPEPGNMH_01241	1.28e-171	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
NPEPGNMH_01242	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
NPEPGNMH_01243	4.94e-44	-	-	-	S	-	-	-	YlzJ-like protein
NPEPGNMH_01244	5.01e-171	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
NPEPGNMH_01245	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NPEPGNMH_01246	1.57e-201	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NPEPGNMH_01247	1.2e-283	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
NPEPGNMH_01248	1.66e-247	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NPEPGNMH_01249	9.94e-142	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NPEPGNMH_01250	5.3e-208	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
NPEPGNMH_01251	1.53e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
NPEPGNMH_01252	1.62e-295	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
NPEPGNMH_01253	1.29e-235	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
NPEPGNMH_01254	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NPEPGNMH_01255	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NPEPGNMH_01256	1.63e-232	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
NPEPGNMH_01257	2e-186	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NPEPGNMH_01258	3.29e-75	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NPEPGNMH_01259	7.83e-60	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
NPEPGNMH_01260	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NPEPGNMH_01261	7.57e-55	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NPEPGNMH_01262	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
NPEPGNMH_01263	2.01e-57	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
NPEPGNMH_01264	5.49e-261	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
NPEPGNMH_01265	1.34e-104	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
NPEPGNMH_01266	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NPEPGNMH_01267	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NPEPGNMH_01268	6.84e-294	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
NPEPGNMH_01269	1.39e-276	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NPEPGNMH_01270	5.77e-179	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
NPEPGNMH_01271	3.84e-187	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NPEPGNMH_01272	9.6e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NPEPGNMH_01273	5.82e-163	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
NPEPGNMH_01274	9.82e-202	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NPEPGNMH_01275	1.49e-168	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
NPEPGNMH_01276	6.91e-101	ylxL	-	-	-	-	-	-	-
NPEPGNMH_01277	6.57e-176	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPEPGNMH_01278	1.66e-39	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
NPEPGNMH_01279	1.8e-53	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
NPEPGNMH_01280	5.06e-144	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
NPEPGNMH_01281	1.56e-103	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
NPEPGNMH_01282	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
NPEPGNMH_01283	8.97e-42	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
NPEPGNMH_01284	1.81e-252	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
NPEPGNMH_01285	1.09e-200	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
NPEPGNMH_01286	5.65e-256	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
NPEPGNMH_01287	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NPEPGNMH_01288	2.74e-244	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NPEPGNMH_01289	1.47e-170	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
NPEPGNMH_01290	1.58e-31	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
NPEPGNMH_01291	1.21e-141	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
NPEPGNMH_01292	5.54e-137	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
NPEPGNMH_01293	2.12e-77	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
NPEPGNMH_01294	1.38e-253	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NPEPGNMH_01295	6.61e-231	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NPEPGNMH_01296	5.59e-78	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
NPEPGNMH_01297	1.09e-179	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
NPEPGNMH_01298	2.81e-96	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
NPEPGNMH_01299	2.31e-314	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
NPEPGNMH_01300	5.08e-84	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
NPEPGNMH_01301	1.79e-91	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
NPEPGNMH_01302	2.11e-308	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
NPEPGNMH_01303	1.92e-144	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
NPEPGNMH_01304	6.08e-230	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NPEPGNMH_01305	2.04e-294	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
NPEPGNMH_01306	7.38e-35	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
NPEPGNMH_01307	5.5e-53	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
NPEPGNMH_01308	7.54e-99	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
NPEPGNMH_01309	1.62e-83	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
NPEPGNMH_01310	1.95e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NPEPGNMH_01311	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NPEPGNMH_01312	3.01e-120	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NPEPGNMH_01313	1.13e-217	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
NPEPGNMH_01314	5.45e-314	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NPEPGNMH_01315	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NPEPGNMH_01316	6.53e-218	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
NPEPGNMH_01317	1.53e-213	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NPEPGNMH_01318	6.77e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NPEPGNMH_01319	1.7e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
NPEPGNMH_01320	4.55e-302	ylqG	-	-	-	-	-	-	-
NPEPGNMH_01321	8.31e-47	ylqG	-	-	-	-	-	-	-
NPEPGNMH_01322	2.04e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NPEPGNMH_01323	1.2e-201	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NPEPGNMH_01324	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NPEPGNMH_01325	1.61e-94	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
NPEPGNMH_01326	1.06e-64	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
NPEPGNMH_01327	1.84e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NPEPGNMH_01328	5.89e-81	ylqD	-	-	S	-	-	-	YlqD protein
NPEPGNMH_01329	2.95e-50	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
NPEPGNMH_01330	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
NPEPGNMH_01331	9.7e-309	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NPEPGNMH_01332	5.64e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NPEPGNMH_01333	1.67e-114	-	-	-	-	-	-	-	-
NPEPGNMH_01334	3.38e-227	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NPEPGNMH_01335	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
NPEPGNMH_01336	2.12e-174	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NPEPGNMH_01337	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NPEPGNMH_01338	3.5e-167	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
NPEPGNMH_01339	1.31e-218	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
NPEPGNMH_01340	8.33e-230	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NPEPGNMH_01341	6.22e-121	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
NPEPGNMH_01342	3.56e-94	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NPEPGNMH_01343	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NPEPGNMH_01344	1.19e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
NPEPGNMH_01345	1.45e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
NPEPGNMH_01346	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
NPEPGNMH_01347	3.65e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_01348	7.06e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
NPEPGNMH_01349	2.83e-157	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
NPEPGNMH_01350	4.68e-153	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
NPEPGNMH_01351	1.37e-215	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NPEPGNMH_01352	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
NPEPGNMH_01353	3.03e-181	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
NPEPGNMH_01354	3.73e-264	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NPEPGNMH_01355	1.82e-264	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NPEPGNMH_01356	2.21e-226	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NPEPGNMH_01357	1.26e-86	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NPEPGNMH_01358	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NPEPGNMH_01359	4.59e-289	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NPEPGNMH_01360	6.21e-39	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NPEPGNMH_01361	5.73e-143	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
NPEPGNMH_01362	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
NPEPGNMH_01363	8.41e-202	yloC	-	-	S	-	-	-	stress-induced protein
NPEPGNMH_01364	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
NPEPGNMH_01365	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
NPEPGNMH_01366	2.28e-108	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
NPEPGNMH_01367	4.33e-189	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
NPEPGNMH_01368	1.24e-186	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
NPEPGNMH_01369	5.56e-142	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
NPEPGNMH_01370	2.62e-285	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
NPEPGNMH_01371	7.32e-230	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
NPEPGNMH_01372	3.58e-183	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
NPEPGNMH_01374	3.8e-150	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NPEPGNMH_01375	1.14e-67	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NPEPGNMH_01376	4.3e-72	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NPEPGNMH_01377	1.33e-224	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NPEPGNMH_01378	3.84e-185	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NPEPGNMH_01379	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
NPEPGNMH_01380	1.31e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
NPEPGNMH_01381	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NPEPGNMH_01382	4.4e-215	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
NPEPGNMH_01383	2.24e-295	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
NPEPGNMH_01384	4.45e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NPEPGNMH_01385	3.52e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NPEPGNMH_01386	2.71e-103	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NPEPGNMH_01387	1.58e-83	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
NPEPGNMH_01388	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NPEPGNMH_01389	6.44e-100	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
NPEPGNMH_01390	3.67e-179	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
NPEPGNMH_01391	1.22e-53	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
NPEPGNMH_01392	5.44e-88	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NPEPGNMH_01393	3.15e-162	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NPEPGNMH_01394	5.53e-205	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
NPEPGNMH_01395	3.58e-51	ylmC	-	-	S	-	-	-	sporulation protein
NPEPGNMH_01396	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
NPEPGNMH_01397	3.84e-189	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
NPEPGNMH_01398	7.99e-180	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPEPGNMH_01399	1.48e-160	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPEPGNMH_01400	1.06e-220	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
NPEPGNMH_01401	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
NPEPGNMH_01402	1.84e-260	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NPEPGNMH_01403	8.45e-300	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NPEPGNMH_01404	2.85e-72	sbp	-	-	S	-	-	-	small basic protein
NPEPGNMH_01405	1.82e-151	ylxX	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_01406	3.45e-146	ylxW	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_01407	1.18e-178	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NPEPGNMH_01408	1.3e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
NPEPGNMH_01409	9.42e-258	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NPEPGNMH_01410	6.64e-237	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
NPEPGNMH_01411	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NPEPGNMH_01412	9.59e-220	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NPEPGNMH_01413	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NPEPGNMH_01414	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
NPEPGNMH_01415	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
NPEPGNMH_01416	1.77e-144	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
NPEPGNMH_01417	3.42e-68	ftsL	-	-	D	-	-	-	Essential cell division protein
NPEPGNMH_01418	4.97e-220	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NPEPGNMH_01419	9.82e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
NPEPGNMH_01420	8.75e-242	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NPEPGNMH_01421	1.52e-100	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NPEPGNMH_01422	1.66e-216	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NPEPGNMH_01423	3.26e-116	ylbP	-	-	K	-	-	-	n-acetyltransferase
NPEPGNMH_01424	5.75e-108	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
NPEPGNMH_01425	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
NPEPGNMH_01426	1.7e-117	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
NPEPGNMH_01428	5.94e-301	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
NPEPGNMH_01429	7.81e-239	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
NPEPGNMH_01430	2.56e-176	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
NPEPGNMH_01431	2.73e-282	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
NPEPGNMH_01432	3.8e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NPEPGNMH_01433	1.86e-102	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
NPEPGNMH_01434	4.36e-52	ylbG	-	-	S	-	-	-	UPF0298 protein
NPEPGNMH_01435	2.34e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
NPEPGNMH_01436	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
NPEPGNMH_01437	3.24e-89	ylbD	-	-	S	-	-	-	Putative coat protein
NPEPGNMH_01438	4.58e-258	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
NPEPGNMH_01439	1.08e-97	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
NPEPGNMH_01440	1.61e-81	ylbA	-	-	S	-	-	-	YugN-like family
NPEPGNMH_01441	1.04e-214	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
NPEPGNMH_01442	6.09e-70	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
NPEPGNMH_01443	1.84e-145	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
NPEPGNMH_01444	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NPEPGNMH_01445	5.85e-253	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NPEPGNMH_01446	1.7e-208	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NPEPGNMH_01447	2.97e-214	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
NPEPGNMH_01448	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NPEPGNMH_01449	2.44e-270	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
NPEPGNMH_01450	6.94e-59	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
NPEPGNMH_01451	4.25e-220	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
NPEPGNMH_01452	9.32e-112	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NPEPGNMH_01453	3.76e-316	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
NPEPGNMH_01454	2.97e-127	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NPEPGNMH_01455	8.92e-44	ylaI	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_01456	4.4e-63	ylaH	-	-	S	-	-	-	YlaH-like protein
NPEPGNMH_01457	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
NPEPGNMH_01458	2.21e-30	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
NPEPGNMH_01459	1.74e-57	ylaE	-	-	-	-	-	-	-
NPEPGNMH_01461	4.51e-118	ylaC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NPEPGNMH_01462	1.44e-56	ylaB	-	-	-	-	-	-	-
NPEPGNMH_01463	0.0	ylaA	-	-	-	-	-	-	-
NPEPGNMH_01464	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
NPEPGNMH_01465	1.28e-223	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NPEPGNMH_01466	1.48e-100	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
NPEPGNMH_01467	9.48e-195	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
NPEPGNMH_01468	4.48e-35	ykzI	-	-	-	-	-	-	-
NPEPGNMH_01469	1.3e-152	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
NPEPGNMH_01470	1.34e-56	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
NPEPGNMH_01471	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
NPEPGNMH_01472	4.55e-83	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
NPEPGNMH_01473	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NPEPGNMH_01474	1.47e-301	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NPEPGNMH_01475	1.75e-227	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NPEPGNMH_01476	1.06e-258	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NPEPGNMH_01477	6.82e-149	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
NPEPGNMH_01478	2.24e-19	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
NPEPGNMH_01479	3.96e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NPEPGNMH_01480	2.03e-187	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
NPEPGNMH_01481	8.98e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
NPEPGNMH_01482	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NPEPGNMH_01483	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NPEPGNMH_01484	1.68e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
NPEPGNMH_01485	9.21e-208	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
NPEPGNMH_01486	4.59e-307	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
NPEPGNMH_01487	2.63e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
NPEPGNMH_01488	6.17e-234	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
NPEPGNMH_01489	1.09e-18	-	-	-	S	-	-	-	Uncharacterized protein YkpC
NPEPGNMH_01490	2.07e-303	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
NPEPGNMH_01491	2.99e-217	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NPEPGNMH_01492	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NPEPGNMH_01493	5.43e-52	ykoA	-	-	-	-	-	-	-
NPEPGNMH_01494	1.72e-134	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NPEPGNMH_01495	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NPEPGNMH_01496	9.99e-216	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
NPEPGNMH_01497	1.49e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
NPEPGNMH_01498	2.1e-269	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
NPEPGNMH_01499	8.25e-79	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPGNMH_01500	9.38e-66	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPGNMH_01501	4.93e-235	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NPEPGNMH_01502	1.6e-151	yknW	-	-	S	-	-	-	Yip1 domain
NPEPGNMH_01503	6.74e-248	yknV	-	-	V	ko:K02021,ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
NPEPGNMH_01504	2.3e-128	yknV	-	-	V	ko:K02021,ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
NPEPGNMH_01505	0.0	yknU	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
NPEPGNMH_01506	6.92e-45	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NPEPGNMH_01507	6.61e-110	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
NPEPGNMH_01508	3.44e-122	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
NPEPGNMH_01509	1.05e-313	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
NPEPGNMH_01510	6.5e-246	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NPEPGNMH_01511	9.21e-142	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NPEPGNMH_01512	1.47e-201	yknT	-	-	-	ko:K06437	-	ko00000	-
NPEPGNMH_01513	8.8e-84	rok	-	-	K	-	-	-	Repressor of ComK
NPEPGNMH_01514	2.8e-28	rok	-	-	K	-	-	-	Repressor of ComK
NPEPGNMH_01515	6.25e-106	ykuV	-	-	CO	-	-	-	thiol-disulfide
NPEPGNMH_01516	9.78e-130	ykuU	-	-	O	-	-	-	Alkyl hydroperoxide reductase
NPEPGNMH_01517	4.1e-181	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
NPEPGNMH_01518	7.23e-51	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
NPEPGNMH_01519	7.99e-276	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NPEPGNMH_01520	1.31e-125	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NPEPGNMH_01521	1.3e-104	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
NPEPGNMH_01522	1.33e-226	ykuO	-	-	-	-	-	-	-
NPEPGNMH_01523	7.72e-114	-	-	-	C	ko:K03839	-	ko00000	Flavodoxin domain
NPEPGNMH_01524	6.52e-216	ccpC	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_01525	5.15e-100	ykuL	-	-	S	-	-	-	CBS domain
NPEPGNMH_01526	7.83e-38	ykzF	-	-	S	-	-	-	Antirepressor AbbA
NPEPGNMH_01527	6.44e-122	-	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
NPEPGNMH_01528	5.16e-50	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_01529	1.76e-298	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
NPEPGNMH_01531	1.52e-120	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
NPEPGNMH_01532	0.0	ybfG	-	-	M	-	-	-	Putative peptidoglycan binding domain
NPEPGNMH_01533	2.61e-45	ybfG	-	-	M	-	-	-	Putative peptidoglycan binding domain
NPEPGNMH_01534	1.83e-182	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPEPGNMH_01535	3.48e-212	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
NPEPGNMH_01536	7.1e-116	ykuD	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_01537	1.13e-12	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
NPEPGNMH_01538	1.81e-269	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
NPEPGNMH_01539	3.71e-110	ykyB	-	-	S	-	-	-	YkyB-like protein
NPEPGNMH_01540	4.24e-217	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
NPEPGNMH_01541	1.05e-22	-	-	-	-	-	-	-	-
NPEPGNMH_01542	5.32e-286	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NPEPGNMH_01543	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NPEPGNMH_01544	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
NPEPGNMH_01545	5.36e-172	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
NPEPGNMH_01546	1.4e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NPEPGNMH_01547	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
NPEPGNMH_01548	5.49e-170	ykwB	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPEPGNMH_01549	2.13e-257	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
NPEPGNMH_01550	1.54e-51	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
NPEPGNMH_01551	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NPEPGNMH_01552	2.3e-36	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NPEPGNMH_01553	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
NPEPGNMH_01554	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NPEPGNMH_01555	3.41e-168	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
NPEPGNMH_01557	3.28e-230	ykvZ	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_01559	7.85e-266	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
NPEPGNMH_01560	3.99e-09	-	-	-	-	-	-	-	-
NPEPGNMH_01561	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
NPEPGNMH_01562	5.79e-117	stoA	-	-	CO	-	-	-	thiol-disulfide
NPEPGNMH_01563	1.12e-302	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NPEPGNMH_01564	9.09e-142	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
NPEPGNMH_01565	2.6e-39	-	-	-	-	-	-	-	-
NPEPGNMH_01566	5.43e-35	ykvS	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_01567	2.67e-62	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
NPEPGNMH_01568	2.5e-169	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
NPEPGNMH_01569	1.85e-48	-	3.5.1.104	-	M	ko:K22278	-	ko00000,ko01000	LysM domain
NPEPGNMH_01570	2.69e-275	-	-	-	M	-	-	-	Glycosyl transferases group 1
NPEPGNMH_01571	9.35e-173	ykvO	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
NPEPGNMH_01572	2.8e-81	ykvN	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_01573	2.36e-125	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NPEPGNMH_01574	3.56e-179	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NPEPGNMH_01575	6.96e-105	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
NPEPGNMH_01576	1.11e-161	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NPEPGNMH_01577	4.26e-230	ykvI	-	-	S	-	-	-	membrane
NPEPGNMH_01578	4.57e-40	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
NPEPGNMH_01579	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
NPEPGNMH_01580	2.01e-178	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
NPEPGNMH_01581	4.91e-170	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
NPEPGNMH_01582	5.17e-99	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
NPEPGNMH_01583	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
NPEPGNMH_01584	5.84e-95	eag	-	-	-	-	-	-	-
NPEPGNMH_01586	8.82e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
NPEPGNMH_01587	1.5e-123	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NPEPGNMH_01588	4.52e-147	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
NPEPGNMH_01589	1.07e-176	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NPEPGNMH_01590	3.39e-295	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
NPEPGNMH_01591	4.81e-296	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NPEPGNMH_01592	1.99e-193	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NPEPGNMH_01593	2.47e-293	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NPEPGNMH_01594	1.62e-253	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NPEPGNMH_01596	2.76e-115	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NPEPGNMH_01597	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NPEPGNMH_01598	3.34e-244	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
NPEPGNMH_01599	8.33e-31	ykzE	-	-	-	-	-	-	-
NPEPGNMH_01601	1.82e-310	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
NPEPGNMH_01602	3.4e-200	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
NPEPGNMH_01603	7.68e-160	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
NPEPGNMH_01604	1.4e-36	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
NPEPGNMH_01605	9.33e-219	rsgI	-	-	S	-	-	-	Anti-sigma factor N-terminus
NPEPGNMH_01606	1.8e-167	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPEPGNMH_01607	4.63e-227	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
NPEPGNMH_01608	4.48e-153	ykoX	-	-	S	-	-	-	membrane-associated protein
NPEPGNMH_01609	0.0	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
NPEPGNMH_01610	7.55e-206	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NPEPGNMH_01611	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
NPEPGNMH_01612	5.72e-239	ykoT	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
NPEPGNMH_01613	0.0	ykoS	-	-	-	-	-	-	-
NPEPGNMH_01614	4.35e-198	ykoQ	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
NPEPGNMH_01615	2.48e-129	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
NPEPGNMH_01616	1.19e-281	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
NPEPGNMH_01617	9.83e-106	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
NPEPGNMH_01618	3.04e-36	ykoL	-	-	-	-	-	-	-
NPEPGNMH_01619	1.63e-25	-	-	-	-	-	-	-	-
NPEPGNMH_01620	1.49e-70	tnrA	-	-	K	-	-	-	transcriptional
NPEPGNMH_01621	9.86e-300	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
NPEPGNMH_01623	1.45e-08	-	-	-	-	-	-	-	-
NPEPGNMH_01624	2.24e-112	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
NPEPGNMH_01625	3.35e-146	ykoI	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
NPEPGNMH_01626	8.05e-312	ykoH	-	-	T	-	-	-	Histidine kinase
NPEPGNMH_01627	1.28e-160	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPEPGNMH_01628	7.28e-144	ykoF	-	-	S	-	-	-	YKOF-related Family
NPEPGNMH_01629	1.39e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
NPEPGNMH_01630	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NPEPGNMH_01631	3.8e-175	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
NPEPGNMH_01632	3.99e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NPEPGNMH_01633	3.66e-226	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
NPEPGNMH_01634	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NPEPGNMH_01635	5.67e-115	guaD	3.5.4.3	-	FJ	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	COG0590 Cytosine adenosine deaminases
NPEPGNMH_01637	8.15e-94	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
NPEPGNMH_01638	1.21e-98	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
NPEPGNMH_01639	2.39e-93	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
NPEPGNMH_01640	3.38e-291	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NPEPGNMH_01641	3.16e-257	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NPEPGNMH_01642	3.26e-141	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NPEPGNMH_01643	5.31e-48	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NPEPGNMH_01644	2.86e-68	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
NPEPGNMH_01645	1.27e-72	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
NPEPGNMH_01646	3.59e-128	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NPEPGNMH_01647	1.57e-128	ykkA	-	-	S	-	-	-	Protein of unknown function (DUF664)
NPEPGNMH_01648	4.81e-168	ykjA	-	-	S	-	-	-	Protein of unknown function (DUF421)
NPEPGNMH_01649	5.85e-13	-	-	-	-	-	-	-	-
NPEPGNMH_01650	2.65e-289	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NPEPGNMH_01651	3.82e-120	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
NPEPGNMH_01652	4.37e-206	ykgA	-	-	E	-	-	-	Amidinotransferase
NPEPGNMH_01653	9.83e-262	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
NPEPGNMH_01654	1.77e-238	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NPEPGNMH_01655	2.56e-219	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NPEPGNMH_01656	1.24e-259	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
NPEPGNMH_01657	4.26e-228	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
NPEPGNMH_01659	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
NPEPGNMH_01660	6.22e-242	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NPEPGNMH_01661	6.35e-226	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPEPGNMH_01662	9.7e-204	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPEPGNMH_01663	2.42e-197	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
NPEPGNMH_01664	1.54e-183	proG	1.5.1.2	-	E	ko:K00286,ko:K02239	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko02044	Pyrroline-5-carboxylate reductase
NPEPGNMH_01665	6.72e-288	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NPEPGNMH_01667	1.34e-230	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
NPEPGNMH_01668	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NPEPGNMH_01670	3.43e-234	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
NPEPGNMH_01671	7.7e-311	steT	-	-	E	ko:K03294	-	ko00000	amino acid
NPEPGNMH_01672	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
NPEPGNMH_01673	1.54e-225	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
NPEPGNMH_01674	1.19e-175	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
NPEPGNMH_01675	1.78e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
NPEPGNMH_01676	5.76e-212	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
NPEPGNMH_01677	8.12e-53	xhlB	-	-	S	-	-	-	SPP1 phage holin
NPEPGNMH_01678	7.71e-52	xhlA	-	-	S	-	-	-	Haemolysin XhlA
NPEPGNMH_01679	1.51e-198	xepA	-	-	-	-	-	-	-
NPEPGNMH_01680	9.34e-33	xkdX	-	-	-	-	-	-	-
NPEPGNMH_01681	8.68e-74	xkdW	-	-	S	-	-	-	XkdW protein
NPEPGNMH_01682	0.0	-	-	-	-	-	-	-	-
NPEPGNMH_01683	4.43e-56	-	-	-	-	-	-	-	-
NPEPGNMH_01684	9.63e-136	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
NPEPGNMH_01685	7.59e-245	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NPEPGNMH_01686	1.97e-92	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
NPEPGNMH_01687	4.32e-53	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
NPEPGNMH_01688	2.31e-232	xkdQ	-	-	G	-	-	-	NLP P60 protein
NPEPGNMH_01689	1.77e-158	xkdP	-	-	S	-	-	-	Lysin motif
NPEPGNMH_01690	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
NPEPGNMH_01691	3.34e-101	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
NPEPGNMH_01692	5.46e-62	xkdM	-	-	S	-	-	-	Phage tail tube protein
NPEPGNMH_01693	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
NPEPGNMH_01694	2.87e-101	xkdJ	-	-	-	-	-	-	-
NPEPGNMH_01695	5.84e-115	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
NPEPGNMH_01696	1.05e-85	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
NPEPGNMH_01697	2.06e-85	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
NPEPGNMH_01698	3.91e-217	xkdG	-	-	S	-	-	-	Phage capsid family
NPEPGNMH_01699	9.88e-177	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
NPEPGNMH_01700	0.0	yqbA	-	-	S	-	-	-	portal protein
NPEPGNMH_01701	0.0	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
NPEPGNMH_01702	1.18e-179	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
NPEPGNMH_01703	5.95e-112	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NPEPGNMH_01707	7.48e-153	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
NPEPGNMH_01708	3.73e-203	xkdB	-	-	K	-	-	-	sequence-specific DNA binding
NPEPGNMH_01710	2.01e-74	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NPEPGNMH_01711	1.53e-144	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
NPEPGNMH_01712	4.54e-204	yjqC	-	-	P	ko:K07217	-	ko00000	Catalase
NPEPGNMH_01713	1.47e-143	yjqB	-	-	S	-	-	-	Pfam:DUF867
NPEPGNMH_01714	3.31e-81	yjqA	-	-	S	-	-	-	Bacterial PH domain
NPEPGNMH_01715	1.37e-220	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
NPEPGNMH_01716	1.79e-55	-	-	-	S	-	-	-	YCII-related domain
NPEPGNMH_01718	1.6e-272	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
NPEPGNMH_01719	6.08e-314	VCP	-	-	O	-	-	-	AAA domain (dynein-related subfamily)
NPEPGNMH_01720	4.87e-106	yjoA	-	-	S	-	-	-	DinB family
NPEPGNMH_01721	1.59e-167	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NPEPGNMH_01722	0.0	uxaA	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
NPEPGNMH_01723	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
NPEPGNMH_01724	6.95e-238	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
NPEPGNMH_01725	1.37e-289	exuT	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	Sugar (and other) transporter
NPEPGNMH_01726	1.34e-196	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
NPEPGNMH_01727	1.66e-274	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
NPEPGNMH_01728	1.6e-246	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
NPEPGNMH_01729	2.02e-248	allD	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
NPEPGNMH_01730	6.34e-316	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
NPEPGNMH_01731	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
NPEPGNMH_01732	2.15e-280	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
NPEPGNMH_01733	1.39e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
NPEPGNMH_01734	8.91e-121	yjlB	-	-	S	-	-	-	Cupin domain
NPEPGNMH_01735	1.09e-225	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
NPEPGNMH_01736	2.79e-175	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NPEPGNMH_01737	9.04e-156	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
NPEPGNMH_01738	8.69e-189	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
NPEPGNMH_01739	1.11e-41	-	-	-	-	-	-	-	-
NPEPGNMH_01740	8.74e-280	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NPEPGNMH_01741	1.48e-289	yjiB	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
NPEPGNMH_01743	1.91e-149	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
NPEPGNMH_01745	1.6e-122	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
NPEPGNMH_01746	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
NPEPGNMH_01747	1.22e-133	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
NPEPGNMH_01748	1.38e-59	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
NPEPGNMH_01749	3.24e-219	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
NPEPGNMH_01750	1.95e-30	yjfB	-	-	S	-	-	-	Putative motility protein
NPEPGNMH_01751	2.22e-108	-	-	-	S	-	-	-	Protein of unknown function (DUF2690)
NPEPGNMH_01752	0.0	yjeA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
NPEPGNMH_01754	5.31e-224	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NPEPGNMH_01755	2.31e-69	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
NPEPGNMH_01756	6.12e-40	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
NPEPGNMH_01757	1.01e-105	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NPEPGNMH_01759	1.36e-121	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
NPEPGNMH_01760	4.79e-78	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
NPEPGNMH_01761	6.2e-241	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
NPEPGNMH_01762	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NPEPGNMH_01763	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
NPEPGNMH_01764	0.000759	-	-	-	-	-	-	-	-
NPEPGNMH_01765	3.42e-181	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
NPEPGNMH_01766	3.8e-63	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
NPEPGNMH_01767	3.29e-121	yqaS	-	-	L	-	-	-	DNA packaging
NPEPGNMH_01768	1.01e-65	-	-	-	S	-	-	-	YjcQ protein
NPEPGNMH_01769	5.68e-100	yjcP	-	-	-	-	-	-	-
NPEPGNMH_01770	2.24e-106	-	-	-	L	-	-	-	Transposase
NPEPGNMH_01773	1.52e-68	yjcN	-	-	-	-	-	-	-
NPEPGNMH_01774	3.75e-269	-	-	-	S	-	-	-	Putative amidase domain
NPEPGNMH_01777	2.58e-274	yjcL	-	-	S	-	-	-	Protein of unknown function (DUF819)
NPEPGNMH_01778	2.13e-129	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
NPEPGNMH_01779	6.4e-281	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
NPEPGNMH_01780	1.98e-273	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
NPEPGNMH_01781	1.63e-178	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
NPEPGNMH_01782	1.2e-121	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
NPEPGNMH_01783	7.75e-94	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPEPGNMH_01784	6.31e-51	-	-	-	-	-	-	-	-
NPEPGNMH_01785	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
NPEPGNMH_01786	1.88e-52	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
NPEPGNMH_01789	3.03e-76	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
NPEPGNMH_01790	1.44e-72	cotV	-	-	S	ko:K06340	-	ko00000	Spore Coat Protein X and V domain
NPEPGNMH_01791	1.08e-54	cotW	-	-	-	ko:K06341	-	ko00000	-
NPEPGNMH_01792	3.55e-110	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
NPEPGNMH_01793	3.12e-124	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
NPEPGNMH_01794	4.57e-108	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
NPEPGNMH_01795	2.32e-107	yjbX	-	-	S	-	-	-	Spore coat protein
NPEPGNMH_01796	1.23e-182	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
NPEPGNMH_01797	8.38e-192	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NPEPGNMH_01798	1.52e-238	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NPEPGNMH_01799	6.78e-174	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NPEPGNMH_01800	5.35e-42	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
NPEPGNMH_01801	1.14e-277	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
NPEPGNMH_01802	4.01e-139	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
NPEPGNMH_01803	5.7e-177	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NPEPGNMH_01804	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NPEPGNMH_01805	8.09e-181	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
NPEPGNMH_01806	9.4e-206	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
NPEPGNMH_01807	2.94e-194	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NPEPGNMH_01808	5.06e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
NPEPGNMH_01809	1.87e-81	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
NPEPGNMH_01810	5.15e-130	yjbK	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_01811	3.42e-127	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NPEPGNMH_01812	8.58e-94	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
NPEPGNMH_01813	1.32e-218	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
NPEPGNMH_01815	2.68e-28	-	-	-	-	-	-	-	-
NPEPGNMH_01816	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
NPEPGNMH_01817	1.31e-283	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
NPEPGNMH_01818	1.78e-147	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NPEPGNMH_01819	4e-52	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
NPEPGNMH_01820	1.03e-81	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
NPEPGNMH_01821	3.51e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NPEPGNMH_01822	5.71e-42	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPEPGNMH_01823	2.18e-78	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPEPGNMH_01824	3.98e-248	yjbB	-	-	EGP	-	-	-	Major Facilitator Superfamily
NPEPGNMH_01825	4.43e-220	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NPEPGNMH_01826	1.37e-249	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NPEPGNMH_01827	7.55e-212	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPEPGNMH_01828	1.03e-212	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPEPGNMH_01829	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
NPEPGNMH_01830	6.15e-235	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
NPEPGNMH_01831	3.18e-190	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
NPEPGNMH_01832	1.03e-208	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPEPGNMH_01833	1.04e-219	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPEPGNMH_01834	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
NPEPGNMH_01835	2.07e-237	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NPEPGNMH_01836	6.15e-234	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NPEPGNMH_01837	9.48e-193	yjaZ	-	-	O	-	-	-	Zn-dependent protease
NPEPGNMH_01838	3.06e-302	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NPEPGNMH_01839	1.21e-170	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NPEPGNMH_01840	2.67e-38	yjzB	-	-	-	-	-	-	-
NPEPGNMH_01841	1.07e-35	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
NPEPGNMH_01842	6.4e-235	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
NPEPGNMH_01843	5.41e-134	yjaV	-	-	-	-	-	-	-
NPEPGNMH_01844	2.42e-182	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
NPEPGNMH_01845	2.17e-23	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
NPEPGNMH_01846	2.51e-39	yjzC	-	-	S	-	-	-	YjzC-like protein
NPEPGNMH_01847	3.66e-226	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NPEPGNMH_01848	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
NPEPGNMH_01849	1.4e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
NPEPGNMH_01850	1.69e-278	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
NPEPGNMH_01851	5.4e-177	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
NPEPGNMH_01852	7.4e-295	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NPEPGNMH_01853	9.02e-256	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NPEPGNMH_01854	3.24e-114	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
NPEPGNMH_01855	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
NPEPGNMH_01856	1.74e-31	-	-	-	S	-	-	-	Proteolipid membrane potential modulator
NPEPGNMH_01857	3.26e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
NPEPGNMH_01858	5.05e-185	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
NPEPGNMH_01859	3.19e-200	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
NPEPGNMH_01860	1.01e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
NPEPGNMH_01861	1.61e-92	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
NPEPGNMH_01862	2.29e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
NPEPGNMH_01863	9.13e-202	yitS	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_01864	0.0	nprB	3.4.24.28	-	E	ko:K01400,ko:K08777	ko02024,map02024	ko00000,ko00001,ko01000,ko01002	Peptidase M4
NPEPGNMH_01865	4.59e-59	yitR	-	-	S	-	-	-	Domain of unknown function (DUF3784)
NPEPGNMH_01866	7.76e-123	-	-	-	-	-	-	-	-
NPEPGNMH_01867	2.08e-77	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
NPEPGNMH_01868	3.29e-127	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
NPEPGNMH_01869	1.42e-218	-	-	-	-	-	-	-	-
NPEPGNMH_01870	4.16e-122	-	-	-	-	-	-	-	-
NPEPGNMH_01871	1.94e-204	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
NPEPGNMH_01872	1.06e-77	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
NPEPGNMH_01873	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NPEPGNMH_01874	8.19e-107	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
NPEPGNMH_01875	7.86e-207	yitH	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NPEPGNMH_01876	1.01e-291	yitG	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
NPEPGNMH_01877	2.14e-283	yitF	5.5.1.27	-	M	ko:K18983	ko00053,map00053	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
NPEPGNMH_01878	6.77e-145	yitE	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NPEPGNMH_01879	4.31e-180	yitD	4.4.1.19	-	S	ko:K08097	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	synthase
NPEPGNMH_01880	1.34e-162	-	3.1.3.71	-	H	ko:K05979	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the ComB family
NPEPGNMH_01881	9.51e-185	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
NPEPGNMH_01882	1.37e-295	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
NPEPGNMH_01883	4.06e-145	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
NPEPGNMH_01884	2.25e-199	yisY	1.11.1.10	-	I	ko:K00433	-	ko00000,ko01000	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NPEPGNMH_01885	2.15e-96	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
NPEPGNMH_01886	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NPEPGNMH_01887	5.42e-140	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
NPEPGNMH_01888	7.28e-122	yisT	-	-	S	-	-	-	DinB family
NPEPGNMH_01889	5.04e-242	yisS	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
NPEPGNMH_01890	1.83e-235	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NPEPGNMH_01891	1.41e-207	yisR	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_01892	1.01e-310	yisQ	-	-	V	-	-	-	Mate efflux family protein
NPEPGNMH_01893	6.82e-193	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
NPEPGNMH_01894	1.85e-115	yizA	-	-	S	-	-	-	Damage-inducible protein DinB
NPEPGNMH_01895	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
NPEPGNMH_01896	7.48e-137	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
NPEPGNMH_01897	0.0	wprA	-	-	O	ko:K13274	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
NPEPGNMH_01898	1.02e-74	yisL	-	-	S	-	-	-	UPF0344 protein
NPEPGNMH_01899	2.66e-219	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
NPEPGNMH_01900	1.33e-116	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
NPEPGNMH_01901	1.52e-32	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
NPEPGNMH_01902	1.82e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
NPEPGNMH_01903	1.76e-47	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
NPEPGNMH_01904	8.23e-93	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
NPEPGNMH_01905	7.36e-34	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
NPEPGNMH_01906	4.08e-88	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
NPEPGNMH_01907	3.3e-43	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
NPEPGNMH_01908	1.34e-66	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
NPEPGNMH_01909	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
NPEPGNMH_01910	1.2e-281	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NPEPGNMH_01911	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
NPEPGNMH_01912	2.86e-210	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
NPEPGNMH_01913	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
NPEPGNMH_01914	9.3e-102	yhjR	-	-	S	-	-	-	Rubrerythrin
NPEPGNMH_01915	3.54e-77	yhjQ	-	-	C	-	-	-	COG1145 Ferredoxin
NPEPGNMH_01916	0.0	-	-	-	S	-	-	-	Sugar transport-related sRNA regulator N-term
NPEPGNMH_01917	1.27e-272	-	-	-	EGP	-	-	-	Transmembrane secretion effector
NPEPGNMH_01918	2.14e-260	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
NPEPGNMH_01919	2.63e-240	yhjM	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_01920	0.0	-	2.6.1.104	-	E	ko:K18653	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
NPEPGNMH_01921	2.63e-205	ntdB	3.1.3.24, 3.1.3.92	-	S	ko:K07024,ko:K18654	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose-6F-phosphate phosphohydrolase
NPEPGNMH_01922	3.98e-257	-	1.1.1.18, 1.1.1.361, 1.1.1.369	-	S	ko:K00010,ko:K18652	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
NPEPGNMH_01923	3.12e-273	glcP	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
NPEPGNMH_01924	2.82e-122	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NPEPGNMH_01925	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
NPEPGNMH_01926	3.09e-118	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NPEPGNMH_01927	4.87e-141	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
NPEPGNMH_01928	2.57e-78	yhjD	-	-	-	-	-	-	-
NPEPGNMH_01929	1.61e-36	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
NPEPGNMH_01930	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NPEPGNMH_01931	5e-57	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
NPEPGNMH_01932	2.55e-216	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
NPEPGNMH_01933	2.19e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
NPEPGNMH_01934	9.84e-45	yhzC	-	-	S	-	-	-	IDEAL
NPEPGNMH_01935	7.82e-204	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPEPGNMH_01936	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
NPEPGNMH_01937	1.85e-260	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
NPEPGNMH_01938	1.47e-118	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
NPEPGNMH_01939	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
NPEPGNMH_01940	1.19e-256	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
NPEPGNMH_01941	9.64e-141	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
NPEPGNMH_01942	2.77e-223	yhfQ	-	-	M	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
NPEPGNMH_01943	2.4e-232	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
NPEPGNMH_01944	2.75e-105	-	-	-	K	-	-	-	acetyltransferase
NPEPGNMH_01945	2.94e-261	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
NPEPGNMH_01946	1.16e-165	yhfN	-	-	O	-	-	-	Peptidase M48
NPEPGNMH_01947	9.1e-118	yhfN	-	-	O	-	-	-	Peptidase M48
NPEPGNMH_01948	2.78e-85	yhfM	-	-	-	-	-	-	-
NPEPGNMH_01949	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
NPEPGNMH_01950	1.82e-144	yhfK	-	-	GM	-	-	-	NmrA-like family
NPEPGNMH_01951	1.21e-246	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
NPEPGNMH_01952	5.93e-183	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
NPEPGNMH_01953	4.77e-289	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NPEPGNMH_01954	3.75e-94	-	-	-	S	-	-	-	ASCH
NPEPGNMH_01955	2.68e-253	yhfE	-	-	G	-	-	-	peptidase M42
NPEPGNMH_01956	1.61e-178	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
NPEPGNMH_01957	8.77e-237	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NPEPGNMH_01958	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
NPEPGNMH_01959	3.49e-133	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
NPEPGNMH_01960	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NPEPGNMH_01961	2.06e-232	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
NPEPGNMH_01962	7.78e-261	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NPEPGNMH_01963	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
NPEPGNMH_01964	1.31e-118	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
NPEPGNMH_01965	1.33e-23	-	-	-	C	-	-	-	Rubrerythrin
NPEPGNMH_01966	8.98e-317	yhfA	-	-	C	-	-	-	membrane
NPEPGNMH_01967	4.8e-295	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NPEPGNMH_01968	5e-162	ecsC	-	-	S	-	-	-	EcsC protein family
NPEPGNMH_01969	3.11e-272	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
NPEPGNMH_01970	2.7e-176	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
NPEPGNMH_01971	3.5e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NPEPGNMH_01972	1.84e-262	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NPEPGNMH_01973	6.32e-104	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
NPEPGNMH_01974	1.74e-54	yhaH	-	-	S	-	-	-	YtxH-like protein
NPEPGNMH_01975	4.92e-148	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
NPEPGNMH_01976	8.48e-73	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
NPEPGNMH_01977	2.83e-48	yhaK	-	-	S	-	-	-	Putative zincin peptidase
NPEPGNMH_01978	2.29e-179	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NPEPGNMH_01979	1.88e-39	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
NPEPGNMH_01980	5.22e-228	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
NPEPGNMH_01981	0.0	yhaN	-	-	L	-	-	-	AAA domain
NPEPGNMH_01982	9.85e-303	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
NPEPGNMH_01983	5.14e-272	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
NPEPGNMH_01984	5.56e-215	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPGNMH_01985	2.29e-36	-	-	-	S	-	-	-	YhzD-like protein
NPEPGNMH_01986	1.6e-172	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
NPEPGNMH_01988	6.51e-114	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
NPEPGNMH_01989	1.85e-267	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
NPEPGNMH_01990	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
NPEPGNMH_01991	8.7e-198	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
NPEPGNMH_01992	6.69e-264	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
NPEPGNMH_01993	7.46e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
NPEPGNMH_01994	1.51e-261	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
NPEPGNMH_01995	3.37e-276	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
NPEPGNMH_01996	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
NPEPGNMH_01997	2.27e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
NPEPGNMH_01998	1.25e-38	sspB	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
NPEPGNMH_01999	3.31e-143	yheG	-	-	GM	-	-	-	NAD(P)H-binding
NPEPGNMH_02000	1.89e-301	yheH	-	-	V	ko:K06147,ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
NPEPGNMH_02001	4.82e-135	yheH	-	-	V	ko:K06147,ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
NPEPGNMH_02002	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
NPEPGNMH_02003	3.85e-109	nhaX	-	-	T	-	-	-	Belongs to the universal stress protein A family
NPEPGNMH_02004	3.94e-307	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
NPEPGNMH_02005	2.23e-197	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
NPEPGNMH_02006	5.7e-200	nodB1	-	-	G	-	-	-	deacetylase
NPEPGNMH_02007	2.93e-180	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NPEPGNMH_02008	4.51e-260	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
NPEPGNMH_02009	3.7e-09	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
NPEPGNMH_02010	5.44e-174	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
NPEPGNMH_02011	1.01e-87	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NPEPGNMH_02012	2.69e-70	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NPEPGNMH_02013	0.0	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
NPEPGNMH_02014	4.37e-285	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
NPEPGNMH_02015	3.44e-97	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
NPEPGNMH_02016	2.18e-304	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
NPEPGNMH_02017	3.9e-143	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NPEPGNMH_02018	6.74e-244	yhdN	-	-	C	-	-	-	Aldo keto reductase
NPEPGNMH_02019	3.24e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NPEPGNMH_02020	6.13e-258	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
NPEPGNMH_02021	4.27e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
NPEPGNMH_02022	1.75e-100	-	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPEPGNMH_02023	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NPEPGNMH_02024	4.29e-310	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NPEPGNMH_02025	8.94e-317	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
NPEPGNMH_02026	1.41e-208	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPEPGNMH_02027	5.51e-263	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
NPEPGNMH_02028	4.93e-210	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
NPEPGNMH_02029	7.21e-204	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
NPEPGNMH_02030	6.98e-84	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
NPEPGNMH_02031	3.99e-232	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
NPEPGNMH_02032	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
NPEPGNMH_02033	5.29e-307	ygxB	-	-	M	-	-	-	Conserved TM helix
NPEPGNMH_02034	1.37e-99	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
NPEPGNMH_02035	2.4e-275	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
NPEPGNMH_02036	1.25e-72	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
NPEPGNMH_02037	1.65e-51	yhdB	-	-	S	-	-	-	YhdB-like protein
NPEPGNMH_02038	5.68e-117	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
NPEPGNMH_02039	5.68e-148	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPEPGNMH_02040	2.29e-273	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
NPEPGNMH_02041	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
NPEPGNMH_02042	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NPEPGNMH_02043	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NPEPGNMH_02044	5.7e-196	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
NPEPGNMH_02045	5.35e-135	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NPEPGNMH_02046	3.78e-247	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NPEPGNMH_02047	4.9e-74	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NPEPGNMH_02048	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NPEPGNMH_02049	3.04e-155	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
NPEPGNMH_02050	1.76e-90	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
NPEPGNMH_02051	4.27e-89	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
NPEPGNMH_02052	8.26e-219	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
NPEPGNMH_02053	3.9e-138	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
NPEPGNMH_02054	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
NPEPGNMH_02055	1.68e-146	yhcQ	-	-	M	-	-	-	Spore coat protein
NPEPGNMH_02056	3.96e-227	yhcP	-	-	-	-	-	-	-
NPEPGNMH_02057	2.69e-111	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NPEPGNMH_02058	3.23e-80	yhcM	-	-	-	-	-	-	-
NPEPGNMH_02059	2.62e-301	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NPEPGNMH_02060	7.76e-251	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
NPEPGNMH_02061	1.34e-195	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
NPEPGNMH_02062	1.91e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
NPEPGNMH_02063	3.45e-212	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NPEPGNMH_02064	6.47e-213	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPGNMH_02065	3.38e-158	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPGNMH_02066	1.67e-79	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
NPEPGNMH_02067	2.92e-69	-	-	-	-	-	-	-	-
NPEPGNMH_02068	3.95e-59	yhcC	-	-	-	-	-	-	-
NPEPGNMH_02069	4.87e-128	yhcB	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Belongs to the WrbA family
NPEPGNMH_02070	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
NPEPGNMH_02071	3.8e-133	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
NPEPGNMH_02072	1.29e-101	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
NPEPGNMH_02073	1.21e-286	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
NPEPGNMH_02074	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
NPEPGNMH_02075	4.08e-110	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
NPEPGNMH_02076	2.29e-96	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
NPEPGNMH_02077	3.4e-143	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
NPEPGNMH_02078	6.53e-113	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NPEPGNMH_02079	4.79e-226	yhbB	-	-	S	-	-	-	Putative amidase domain
NPEPGNMH_02080	5.09e-285	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NPEPGNMH_02081	1.92e-147	yhzB	-	-	S	-	-	-	B3/4 domain
NPEPGNMH_02083	1.48e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
NPEPGNMH_02084	2.79e-102	ygaO	-	-	-	-	-	-	-
NPEPGNMH_02085	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NPEPGNMH_02087	9.35e-276	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
NPEPGNMH_02088	5.86e-190	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NPEPGNMH_02089	1.78e-219	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
NPEPGNMH_02090	4.15e-185	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NPEPGNMH_02091	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
NPEPGNMH_02093	0.0	ygaK	-	-	C	-	-	-	Berberine and berberine like
NPEPGNMH_02094	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NPEPGNMH_02096	6.95e-173	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
NPEPGNMH_02097	3.88e-37	-	-	-	-	-	-	-	-
NPEPGNMH_02098	2.22e-185	spo0M	-	-	S	ko:K06377	-	ko00000	COG4326 Sporulation control protein
NPEPGNMH_02136	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NPEPGNMH_02137	2.96e-265	glgC	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NPEPGNMH_02138	1.58e-239	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Glucose-1-phosphate adenylyltransferase, GlgD subunit
NPEPGNMH_02139	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
NPEPGNMH_02140	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NPEPGNMH_02141	1.97e-101	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
NPEPGNMH_02142	9.43e-263	cotI	-	-	S	ko:K06331	-	ko00000	Spore coat protein
NPEPGNMH_02143	1.75e-276	cotSA	-	-	M	ko:K06338	-	ko00000	Glycosyl transferases group 1
NPEPGNMH_02144	1.7e-263	cotS	-	-	S	ko:K06337	-	ko00000	Seems to be required for the assembly of the CotSA protein in spores
NPEPGNMH_02146	3.7e-300	-	-	-	M	ko:K06338	-	ko00000	Glycosyltransferase Family 4
NPEPGNMH_02147	7.74e-231	ytcB	-	-	M	-	-	-	NAD-dependent epimerase dehydratase
NPEPGNMH_02148	2.03e-310	ytcA	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NPEPGNMH_02149	1.7e-196	ytdA	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
NPEPGNMH_02150	8.68e-169	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
NPEPGNMH_02151	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
NPEPGNMH_02152	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NPEPGNMH_02153	5.09e-199	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NPEPGNMH_02154	3.45e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NPEPGNMH_02155	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NPEPGNMH_02156	1.22e-273	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NPEPGNMH_02157	1.13e-218	troA	-	-	P	ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
NPEPGNMH_02158	1.83e-180	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NPEPGNMH_02159	1.64e-299	mntC	-	-	P	ko:K11705,ko:K11708,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NPEPGNMH_02160	9.65e-194	mntD	-	-	P	ko:K11709,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
NPEPGNMH_02161	2.43e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
NPEPGNMH_02162	2.96e-241	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
NPEPGNMH_02163	2.81e-316	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
NPEPGNMH_02164	5.02e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
NPEPGNMH_02165	8.96e-134	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
NPEPGNMH_02166	8.36e-113	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NPEPGNMH_02167	8.26e-96	ytkA	-	-	S	-	-	-	YtkA-like
NPEPGNMH_02169	1.8e-99	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
NPEPGNMH_02170	1.59e-81	ytkC	-	-	S	-	-	-	Bacteriophage holin family
NPEPGNMH_02171	4.47e-113	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
NPEPGNMH_02172	1.32e-183	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NPEPGNMH_02173	1.5e-184	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NPEPGNMH_02174	2.77e-242	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NPEPGNMH_02175	6.67e-191	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
NPEPGNMH_02176	2.85e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
NPEPGNMH_02177	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NPEPGNMH_02178	2.26e-286	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NPEPGNMH_02179	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
NPEPGNMH_02180	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
NPEPGNMH_02181	8.35e-88	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NPEPGNMH_02182	2.33e-192	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
NPEPGNMH_02183	1.96e-275	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
NPEPGNMH_02184	6.76e-137	ytqB	-	-	J	-	-	-	Putative rRNA methylase
NPEPGNMH_02185	4.06e-245	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
NPEPGNMH_02186	1.27e-55	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
NPEPGNMH_02188	2.68e-87	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
NPEPGNMH_02189	1.03e-207	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPGNMH_02190	3.35e-222	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
NPEPGNMH_02191	1.07e-189	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
NPEPGNMH_02192	1.02e-163	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPGNMH_02193	5.92e-298	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
NPEPGNMH_02194	1.77e-167	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPEPGNMH_02195	1.58e-239	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
NPEPGNMH_02196	3.83e-179	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
NPEPGNMH_02197	0.0	bceB	-	-	V	ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
NPEPGNMH_02198	2.02e-78	yttA	-	-	S	-	-	-	Pfam Transposase IS66
NPEPGNMH_02199	2.98e-269	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
NPEPGNMH_02200	6.61e-184	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
NPEPGNMH_02201	3.63e-72	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
NPEPGNMH_02202	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
NPEPGNMH_02203	1.22e-68	ytwF	-	-	P	-	-	-	Sulfurtransferase
NPEPGNMH_02204	2.19e-262	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
NPEPGNMH_02205	1.32e-186	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
NPEPGNMH_02206	2.86e-215	amyD	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NPEPGNMH_02207	8.26e-149	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NPEPGNMH_02208	9.02e-153	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NPEPGNMH_02209	1.12e-244	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
NPEPGNMH_02210	1.43e-222	-	-	-	S	-	-	-	Acetyl xylan esterase (AXE1)
NPEPGNMH_02211	4.04e-182	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NPEPGNMH_02212	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NPEPGNMH_02213	3.73e-284	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NPEPGNMH_02214	5.04e-164	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NPEPGNMH_02215	4.57e-244	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NPEPGNMH_02216	2.64e-287	bioI	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
NPEPGNMH_02217	9.85e-170	ytbQ	1.1.1.203, 1.1.1.388	-	GM	ko:K18981,ko:K19243	ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase/dehydratase family
NPEPGNMH_02218	6.19e-193	ytcP	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
NPEPGNMH_02219	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
NPEPGNMH_02220	0.0	ytdP	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_02221	2.27e-221	lplB13	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
NPEPGNMH_02222	2.23e-286	yteR	3.2.1.172	GH105	G	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
NPEPGNMH_02223	5.81e-95	yteS	-	-	G	-	-	-	transport
NPEPGNMH_02224	0.0	yteT	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
NPEPGNMH_02225	1.97e-152	yteU	-	-	S	-	-	-	Integral membrane protein
NPEPGNMH_02226	2.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
NPEPGNMH_02227	1.95e-11	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
NPEPGNMH_02228	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
NPEPGNMH_02229	6.99e-294	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
NPEPGNMH_02230	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NPEPGNMH_02231	9.04e-171	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NPEPGNMH_02232	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
NPEPGNMH_02233	2.4e-169	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NPEPGNMH_02234	8.45e-263	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
NPEPGNMH_02235	1.73e-288	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
NPEPGNMH_02236	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
NPEPGNMH_02237	3e-221	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
NPEPGNMH_02238	7.71e-133	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NPEPGNMH_02239	4.92e-212	ytlQ	-	-	-	-	-	-	-
NPEPGNMH_02240	2.22e-231	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
NPEPGNMH_02241	8.15e-276	amyX	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
NPEPGNMH_02242	5.19e-217	amyX	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
NPEPGNMH_02243	3.02e-192	ytmP	-	-	M	-	-	-	Phosphotransferase
NPEPGNMH_02244	9.51e-61	ytzH	-	-	S	-	-	-	YtzH-like protein
NPEPGNMH_02245	7.53e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NPEPGNMH_02246	2.16e-193	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
NPEPGNMH_02247	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
NPEPGNMH_02248	4.06e-68	ytzB	-	-	S	-	-	-	small secreted protein
NPEPGNMH_02249	2.24e-262	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
NPEPGNMH_02250	7.02e-103	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
NPEPGNMH_02251	3.17e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
NPEPGNMH_02252	1.02e-191	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
NPEPGNMH_02253	1.78e-140	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NPEPGNMH_02254	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
NPEPGNMH_02255	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
NPEPGNMH_02256	1.67e-63	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NPEPGNMH_02257	3.17e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
NPEPGNMH_02258	1.9e-72	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
NPEPGNMH_02259	7.64e-250	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NPEPGNMH_02260	4.16e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
NPEPGNMH_02261	1.18e-187	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
NPEPGNMH_02262	4.81e-143	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
NPEPGNMH_02263	6.51e-293	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
NPEPGNMH_02264	6.16e-152	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
NPEPGNMH_02265	2.43e-156	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
NPEPGNMH_02266	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NPEPGNMH_02267	6.47e-304	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NPEPGNMH_02269	2.01e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NPEPGNMH_02270	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
NPEPGNMH_02271	1.95e-114	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
NPEPGNMH_02272	2.94e-142	yttP	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_02273	3.73e-198	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NPEPGNMH_02274	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NPEPGNMH_02275	1.17e-304	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
NPEPGNMH_02276	1.22e-269	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
NPEPGNMH_02277	6.26e-289	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NPEPGNMH_02278	2.12e-40	-	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
NPEPGNMH_02279	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NPEPGNMH_02280	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
NPEPGNMH_02281	2.92e-190	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NPEPGNMH_02282	6.13e-233	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
NPEPGNMH_02283	7.05e-113	yteJ	-	-	S	-	-	-	RDD family
NPEPGNMH_02284	5.03e-150	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
NPEPGNMH_02285	2.24e-96	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
NPEPGNMH_02286	1.93e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NPEPGNMH_02287	3.78e-224	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
NPEPGNMH_02288	1.52e-280	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NPEPGNMH_02289	8.14e-115	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
NPEPGNMH_02290	1.06e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
NPEPGNMH_02291	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
NPEPGNMH_02293	1.98e-182	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPEPGNMH_02294	1.91e-166	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
NPEPGNMH_02295	4.99e-223	ytlI	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
NPEPGNMH_02296	8.39e-130	ytmI	-	-	K	ko:K00680	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
NPEPGNMH_02297	3.18e-195	-	-	-	ET	ko:K16956,ko:K16957,ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
NPEPGNMH_02298	4.01e-194	tcyK	-	-	M	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
NPEPGNMH_02299	1.66e-157	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NPEPGNMH_02300	4.08e-156	-	-	-	U	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NPEPGNMH_02301	6.61e-183	tcyN	-	-	E	ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
NPEPGNMH_02302	1.52e-237	ytmO	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPEPGNMH_02303	5.26e-63	ytnI	-	-	O	-	-	-	COG0695 Glutaredoxin and related proteins
NPEPGNMH_02304	0.0	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPEPGNMH_02305	1.69e-166	-	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin kinase
NPEPGNMH_02306	2.09e-306	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
NPEPGNMH_02307	2.24e-206	ytnM	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NPEPGNMH_02308	1.13e-308	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
NPEPGNMH_02309	2.15e-63	ytpI	-	-	S	-	-	-	YtpI-like protein
NPEPGNMH_02310	1.24e-230	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
NPEPGNMH_02311	1.15e-39	-	-	-	-	-	-	-	-
NPEPGNMH_02312	5.12e-112	ytrI	-	-	-	-	-	-	-
NPEPGNMH_02313	2.45e-75	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
NPEPGNMH_02314	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
NPEPGNMH_02315	6.01e-287	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
NPEPGNMH_02316	2.17e-208	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NPEPGNMH_02317	9.82e-234	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NPEPGNMH_02318	1.62e-229	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NPEPGNMH_02319	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
NPEPGNMH_02320	5.68e-83	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
NPEPGNMH_02321	2.73e-245	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
NPEPGNMH_02322	9.38e-95	ytwI	-	-	S	-	-	-	membrane
NPEPGNMH_02323	1.17e-267	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
NPEPGNMH_02324	2.28e-309	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
NPEPGNMH_02325	2.55e-218	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
NPEPGNMH_02326	1.62e-169	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPEPGNMH_02327	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
NPEPGNMH_02328	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NPEPGNMH_02329	7e-203	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NPEPGNMH_02330	1.68e-138	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
NPEPGNMH_02331	2.82e-126	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NPEPGNMH_02332	4.54e-205	ytbE	-	-	S	-	-	-	reductase
NPEPGNMH_02333	5.44e-260	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
NPEPGNMH_02334	9.85e-88	ytcD	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_02335	1.22e-246	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NPEPGNMH_02336	2.42e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NPEPGNMH_02337	2.42e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NPEPGNMH_02338	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
NPEPGNMH_02339	1.05e-221	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
NPEPGNMH_02340	9.77e-144	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
NPEPGNMH_02341	3.78e-34	ytxC	-	-	S	-	-	-	YtxC-like family
NPEPGNMH_02342	4.85e-153	ytxC	-	-	S	-	-	-	YtxC-like family
NPEPGNMH_02343	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NPEPGNMH_02344	2.07e-191	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
NPEPGNMH_02345	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NPEPGNMH_02346	2.9e-168	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
NPEPGNMH_02347	2.08e-85	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NPEPGNMH_02348	5.34e-150	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NPEPGNMH_02350	1.81e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NPEPGNMH_02351	3.93e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
NPEPGNMH_02352	3.26e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NPEPGNMH_02353	1.27e-59	ysdA	-	-	S	-	-	-	Membrane
NPEPGNMH_02354	1.96e-89	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
NPEPGNMH_02355	4.32e-28	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
NPEPGNMH_02356	1.72e-223	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
NPEPGNMH_02357	4.21e-243	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
NPEPGNMH_02358	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
NPEPGNMH_02359	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
NPEPGNMH_02360	1.7e-170	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NPEPGNMH_02361	1.05e-187	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
NPEPGNMH_02362	1.47e-288	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NPEPGNMH_02363	0.0	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
NPEPGNMH_02364	6.77e-219	araP	-	-	G	ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
NPEPGNMH_02365	6.34e-192	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
NPEPGNMH_02366	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
NPEPGNMH_02367	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
NPEPGNMH_02369	8.17e-52	ysfE	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	lactoylglutathione lyase activity
NPEPGNMH_02370	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
NPEPGNMH_02371	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
NPEPGNMH_02372	6.71e-265	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
NPEPGNMH_02373	7.54e-44	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
NPEPGNMH_02374	7.68e-172	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NPEPGNMH_02375	2.81e-58	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NPEPGNMH_02376	2.95e-129	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NPEPGNMH_02377	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NPEPGNMH_02378	6.77e-219	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NPEPGNMH_02379	1.04e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NPEPGNMH_02380	1.09e-111	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
NPEPGNMH_02381	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
NPEPGNMH_02382	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NPEPGNMH_02383	3.76e-89	yshE	-	-	S	ko:K08989	-	ko00000	membrane
NPEPGNMH_02384	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NPEPGNMH_02385	1.21e-130	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
NPEPGNMH_02386	2.2e-176	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
NPEPGNMH_02387	1.28e-179	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
NPEPGNMH_02388	3.02e-228	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
NPEPGNMH_02390	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
NPEPGNMH_02391	1.12e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
NPEPGNMH_02392	7e-91	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NPEPGNMH_02393	2.65e-272	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NPEPGNMH_02394	4.83e-276	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
NPEPGNMH_02395	8.53e-104	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
NPEPGNMH_02396	1.35e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
NPEPGNMH_02397	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
NPEPGNMH_02398	1.15e-189	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
NPEPGNMH_02399	1.6e-103	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
NPEPGNMH_02400	1.81e-41	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
NPEPGNMH_02401	1.6e-98	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NPEPGNMH_02402	1.15e-196	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
NPEPGNMH_02403	8.03e-256	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
NPEPGNMH_02404	3.53e-171	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NPEPGNMH_02405	1.06e-132	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NPEPGNMH_02406	4.05e-119	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
NPEPGNMH_02408	1.01e-184	ysnF	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_02409	3.32e-107	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
NPEPGNMH_02411	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
NPEPGNMH_02412	5.05e-110	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
NPEPGNMH_02413	9.59e-245	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NPEPGNMH_02414	3.63e-23	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NPEPGNMH_02415	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NPEPGNMH_02416	1.06e-255	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NPEPGNMH_02417	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NPEPGNMH_02418	5.35e-150	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NPEPGNMH_02419	2.73e-240	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
NPEPGNMH_02420	8.87e-287	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NPEPGNMH_02421	1.15e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NPEPGNMH_02422	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
NPEPGNMH_02423	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NPEPGNMH_02424	7.6e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
NPEPGNMH_02425	8.23e-117	ysxD	-	-	-	-	-	-	-
NPEPGNMH_02426	6.39e-316	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NPEPGNMH_02427	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
NPEPGNMH_02428	2.66e-221	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NPEPGNMH_02429	1.57e-187	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
NPEPGNMH_02430	6.39e-234	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
NPEPGNMH_02431	8.99e-315	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
NPEPGNMH_02432	0.0	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
NPEPGNMH_02433	8.1e-93	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NPEPGNMH_02434	8.87e-150	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NPEPGNMH_02435	1.53e-35	-	-	-	-	-	-	-	-
NPEPGNMH_02436	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NPEPGNMH_02437	1.58e-267	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
NPEPGNMH_02438	3.15e-109	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
NPEPGNMH_02439	1.05e-204	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
NPEPGNMH_02440	1.73e-132	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
NPEPGNMH_02441	8.35e-163	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
NPEPGNMH_02442	5.26e-235	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
NPEPGNMH_02443	1.91e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
NPEPGNMH_02444	3.74e-29	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
NPEPGNMH_02445	6.22e-71	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
NPEPGNMH_02446	4.3e-158	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NPEPGNMH_02447	2.91e-186	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
NPEPGNMH_02448	1.83e-187	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
NPEPGNMH_02449	3.74e-208	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
NPEPGNMH_02450	6.34e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
NPEPGNMH_02451	2.66e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
NPEPGNMH_02452	2.7e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
NPEPGNMH_02453	4.25e-139	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
NPEPGNMH_02454	9.66e-309	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NPEPGNMH_02455	4.75e-96	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
NPEPGNMH_02456	4.99e-209	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
NPEPGNMH_02457	5.02e-123	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
NPEPGNMH_02458	1.27e-294	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
NPEPGNMH_02459	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
NPEPGNMH_02460	8.17e-208	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
NPEPGNMH_02461	7.94e-273	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NPEPGNMH_02462	1.71e-217	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
NPEPGNMH_02463	7.28e-70	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NPEPGNMH_02464	8.63e-165	yebC	-	-	K	-	-	-	transcriptional regulatory protein
NPEPGNMH_02465	0.0	yrbD	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
NPEPGNMH_02466	2.42e-47	-	-	-	S	-	-	-	Family of unknown function (DUF5412)
NPEPGNMH_02468	2.32e-152	yrzF	-	-	T	-	-	-	serine threonine protein kinase
NPEPGNMH_02469	2.77e-248	idhA	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
NPEPGNMH_02470	0.0	csbX	-	-	EGP	-	-	-	the major facilitator superfamily
NPEPGNMH_02471	1.99e-53	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
NPEPGNMH_02472	3.16e-51	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
NPEPGNMH_02473	2.84e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NPEPGNMH_02474	9.14e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NPEPGNMH_02475	2.91e-30	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
NPEPGNMH_02476	6.03e-248	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NPEPGNMH_02477	4.74e-292	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NPEPGNMH_02478	1.29e-52	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
NPEPGNMH_02479	1.07e-98	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
NPEPGNMH_02480	6.34e-147	yrbG	-	-	S	-	-	-	membrane
NPEPGNMH_02481	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NPEPGNMH_02482	1.93e-65	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
NPEPGNMH_02483	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NPEPGNMH_02484	6.51e-114	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
NPEPGNMH_02485	1.07e-64	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
NPEPGNMH_02486	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
NPEPGNMH_02487	2.53e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NPEPGNMH_02488	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NPEPGNMH_02489	1.6e-89	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NPEPGNMH_02490	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
NPEPGNMH_02492	1.27e-311	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
NPEPGNMH_02493	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NPEPGNMH_02494	3.4e-178	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
NPEPGNMH_02495	8.5e-304	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
NPEPGNMH_02496	8.12e-93	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
NPEPGNMH_02497	2.67e-272	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
NPEPGNMH_02498	1.19e-280	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NPEPGNMH_02499	1.01e-20	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
NPEPGNMH_02500	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NPEPGNMH_02501	1.23e-108	yrrD	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_02502	8.4e-42	yrzR	-	-	-	-	-	-	-
NPEPGNMH_02503	5.38e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
NPEPGNMH_02504	9.26e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NPEPGNMH_02505	2.28e-139	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NPEPGNMH_02506	1.28e-187	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
NPEPGNMH_02507	9.37e-170	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
NPEPGNMH_02508	1.91e-43	yrrI	-	-	S	-	-	-	AI-2E family transporter
NPEPGNMH_02509	5.66e-188	yrrI	-	-	S	-	-	-	AI-2E family transporter
NPEPGNMH_02510	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NPEPGNMH_02511	2.22e-55	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
NPEPGNMH_02512	5.49e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NPEPGNMH_02513	2.94e-60	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
NPEPGNMH_02514	7.51e-242	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NPEPGNMH_02515	1.7e-155	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
NPEPGNMH_02516	6.57e-224	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
NPEPGNMH_02517	4.62e-313	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
NPEPGNMH_02518	4.51e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
NPEPGNMH_02519	1.14e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NPEPGNMH_02520	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
NPEPGNMH_02521	1.42e-102	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
NPEPGNMH_02522	7.27e-38	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
NPEPGNMH_02523	7.23e-155	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
NPEPGNMH_02524	1.97e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NPEPGNMH_02525	7.04e-218	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
NPEPGNMH_02526	4.24e-269	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
NPEPGNMH_02527	6.93e-49	yrhC	-	-	S	-	-	-	YrhC-like protein
NPEPGNMH_02528	4.26e-103	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
NPEPGNMH_02529	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
NPEPGNMH_02530	1.08e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
NPEPGNMH_02531	1.38e-183	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
NPEPGNMH_02533	9.39e-08	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
NPEPGNMH_02534	1.1e-126	yrhH	-	-	Q	-	-	-	methyltransferase
NPEPGNMH_02535	7.05e-67	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
NPEPGNMH_02536	2.05e-59	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
NPEPGNMH_02537	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
NPEPGNMH_02538	2.67e-62	yrhK	-	-	S	-	-	-	YrhK-like protein
NPEPGNMH_02539	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
NPEPGNMH_02540	3.67e-193	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
NPEPGNMH_02541	4.37e-56	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NPEPGNMH_02542	7.17e-24	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NPEPGNMH_02543	5.9e-194	yrhO	-	-	K	-	-	-	Archaeal transcriptional regulator TrmB
NPEPGNMH_02544	5.63e-137	yrhP	-	-	E	-	-	-	LysE type translocator
NPEPGNMH_02545	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
NPEPGNMH_02546	0.0	levR	-	-	K	-	-	-	PTS system fructose IIA component
NPEPGNMH_02547	2.66e-97	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
NPEPGNMH_02548	7.63e-107	ptnA	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11195	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system mannose fructose sorbose family
NPEPGNMH_02549	6.11e-168	levF	-	-	G	ko:K02746,ko:K02795,ko:K11196	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
NPEPGNMH_02550	1.39e-192	levG	-	-	G	ko:K02771,ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
NPEPGNMH_02551	0.0	sacC	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
NPEPGNMH_02552	1.58e-116	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
NPEPGNMH_02553	4.3e-256	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
NPEPGNMH_02554	3.03e-40	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	peroxiredoxin activity
NPEPGNMH_02555	3.17e-68	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
NPEPGNMH_02556	7.23e-66	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
NPEPGNMH_02557	1.05e-36	yraE	-	-	-	ko:K06440	-	ko00000	-
NPEPGNMH_02558	9.1e-284	adhB	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NPEPGNMH_02559	9.61e-84	yraF	-	-	M	-	-	-	Spore coat protein
NPEPGNMH_02560	4.19e-50	yraG	-	-	-	ko:K06440	-	ko00000	-
NPEPGNMH_02561	6.62e-87	-	-	-	E	-	-	-	Glyoxalase-like domain
NPEPGNMH_02562	2.92e-81	-	-	-	T	-	-	-	sh3 domain protein
NPEPGNMH_02563	6.61e-80	-	-	-	T	-	-	-	sh3 domain protein
NPEPGNMH_02564	4.9e-200	-	-	-	S	-	-	-	Alpha beta hydrolase
NPEPGNMH_02565	6.15e-57	yraL	-	-	S	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPEPGNMH_02566	5.73e-202	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
NPEPGNMH_02568	7.25e-264	yraM	-	-	S	-	-	-	PrpF protein
NPEPGNMH_02569	5.13e-211	yraN	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_02570	9.19e-287	yraO	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
NPEPGNMH_02571	5.96e-240	yrpG	-	-	C	-	-	-	Aldo/keto reductase family
NPEPGNMH_02572	1.1e-124	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NPEPGNMH_02573	9.28e-170	zinT	-	-	S	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
NPEPGNMH_02575	5.87e-163	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
NPEPGNMH_02576	8.73e-191	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
NPEPGNMH_02577	3.79e-249	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
NPEPGNMH_02578	2.66e-215	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
NPEPGNMH_02579	1.47e-120	yrdA	-	-	S	-	-	-	DinB family
NPEPGNMH_02580	2.28e-75	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
NPEPGNMH_02581	7.37e-133	yrdC	-	-	Q	-	-	-	Isochorismatase family
NPEPGNMH_02583	1.75e-295	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
NPEPGNMH_02584	1.07e-61	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
NPEPGNMH_02585	1.44e-104	bkdR	-	-	K	-	-	-	helix_turn_helix ASNC type
NPEPGNMH_02586	2.29e-176	azlC	-	-	E	-	-	-	AzlC protein
NPEPGNMH_02587	1.97e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
NPEPGNMH_02588	2.22e-295	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
NPEPGNMH_02590	2.08e-209	-	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
NPEPGNMH_02591	1.75e-87	yodA	-	-	S	-	-	-	tautomerase
NPEPGNMH_02592	2.26e-216	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
NPEPGNMH_02593	2.58e-255	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
NPEPGNMH_02594	1.2e-204	-	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_02595	1.53e-219	yrdR	-	-	EG	-	-	-	EamA-like transporter family
NPEPGNMH_02596	7.28e-25	-	-	-	S	-	-	-	YrzO-like protein
NPEPGNMH_02597	1.58e-301	yrkA	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
NPEPGNMH_02598	3.73e-109	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
NPEPGNMH_02599	1.31e-269	blt	-	-	EGP	ko:K08153,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
NPEPGNMH_02600	2.15e-195	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NPEPGNMH_02601	3.81e-139	yrkC	-	-	G	-	-	-	Cupin domain
NPEPGNMH_02602	6.83e-38	-	-	-	-	-	-	-	-
NPEPGNMH_02603	4.38e-52	yrkD	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_02604	2.38e-109	yrkE	-	-	O	-	-	-	DsrE/DsrF/DrsH-like family
NPEPGNMH_02605	2.04e-129	yrkF	-	-	OP	-	-	-	Belongs to the sulfur carrier protein TusA family
NPEPGNMH_02606	3.43e-260	yrkH	-	-	P	-	-	-	Rhodanese Homology Domain
NPEPGNMH_02607	1.11e-49	yrkI	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
NPEPGNMH_02608	1.14e-31	yrkJ	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NPEPGNMH_02609	4.06e-110	yrkJ	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NPEPGNMH_02610	3.13e-104	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
NPEPGNMH_02611	5.71e-126	yrkL	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
NPEPGNMH_02612	6.12e-134	yrkN	-	-	K	-	-	-	Acetyltransferase (GNAT) family
NPEPGNMH_02613	7.53e-283	yrkO	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
NPEPGNMH_02614	1.24e-164	yrkP	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulator
NPEPGNMH_02615	7.32e-306	yrkQ	-	-	T	-	-	-	Histidine kinase
NPEPGNMH_02616	2.15e-90	psiE	-	-	S	ko:K13256	-	ko00000	Protein PsiE homolog
NPEPGNMH_02617	1.42e-78	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPEPGNMH_02618	2.25e-131	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
NPEPGNMH_02619	8.73e-132	yqaC	-	-	F	-	-	-	adenylate kinase activity
NPEPGNMH_02621	1.25e-74	-	-	-	K	-	-	-	sequence-specific DNA binding
NPEPGNMH_02622	3.43e-49	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NPEPGNMH_02624	1.27e-134	-	-	-	-	-	-	-	-
NPEPGNMH_02628	9.38e-229	yqaJ	-	-	L	-	-	-	YqaJ-like viral recombinase domain
NPEPGNMH_02629	1.1e-198	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
NPEPGNMH_02630	3.33e-159	yqaL	-	-	L	-	-	-	DnaD domain protein
NPEPGNMH_02631	4.9e-214	yqaM	-	-	L	-	-	-	IstB-like ATP binding protein
NPEPGNMH_02633	1.38e-97	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
NPEPGNMH_02634	2.49e-43	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
NPEPGNMH_02635	7.56e-214	-	-	-	-	-	-	-	-
NPEPGNMH_02636	1.58e-105	yqaQ	-	-	L	-	-	-	Transposase
NPEPGNMH_02637	2.27e-33	yqaS	-	-	L	-	-	-	DNA packaging
NPEPGNMH_02638	5.31e-116	yqaS	-	-	L	-	-	-	DNA packaging
NPEPGNMH_02639	0.0	yqaT	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
NPEPGNMH_02640	0.0	yqbA	-	-	S	-	-	-	portal protein
NPEPGNMH_02641	1.73e-217	-	-	-	S	-	-	-	Phage Mu protein F like protein
NPEPGNMH_02642	2.13e-149	-	-	-	-	-	-	-	-
NPEPGNMH_02643	5.46e-186	yqbD	-	-	L	-	-	-	Putative phage serine protease XkdF
NPEPGNMH_02644	9.21e-216	xkdG	-	-	S	-	-	-	Phage capsid family
NPEPGNMH_02645	2.47e-68	-	-	-	S	-	-	-	YqbF, hypothetical protein domain
NPEPGNMH_02646	7.09e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF3199)
NPEPGNMH_02647	7.08e-85	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
NPEPGNMH_02648	7.59e-123	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
NPEPGNMH_02649	3.24e-102	yqbJ	-	-	-	-	-	-	-
NPEPGNMH_02650	2.52e-36	-	-	-	-	-	-	-	-
NPEPGNMH_02651	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
NPEPGNMH_02652	4.23e-99	xkdM	-	-	S	-	-	-	Phage tail tube protein
NPEPGNMH_02654	1.51e-33	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
NPEPGNMH_02655	4.66e-41	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
NPEPGNMH_02656	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
NPEPGNMH_02657	6.56e-156	xkdP	-	-	S	-	-	-	Lysin motif
NPEPGNMH_02658	1.02e-231	xkdQ	-	-	G	-	-	-	NLP P60 protein
NPEPGNMH_02659	6.68e-52	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
NPEPGNMH_02660	1.14e-91	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
NPEPGNMH_02661	7.02e-199	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NPEPGNMH_02662	4.58e-134	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
NPEPGNMH_02663	3e-54	-	-	-	-	-	-	-	-
NPEPGNMH_02664	2.91e-283	-	-	-	-	-	-	-	-
NPEPGNMH_02665	1.01e-73	xkdW	-	-	S	-	-	-	XkdW protein
NPEPGNMH_02666	9.34e-33	-	-	-	-	-	-	-	-
NPEPGNMH_02667	2.45e-213	xepA	-	-	-	-	-	-	-
NPEPGNMH_02668	8.36e-89	-	-	-	S	-	-	-	Bacteriophage holin family
NPEPGNMH_02669	9.72e-187	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
NPEPGNMH_02672	1.66e-136	-	-	-	S	ko:K21492	-	ko00000,ko02048	Suppressor of fused protein (SUFU)
NPEPGNMH_02673	0.0	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
NPEPGNMH_02676	8.68e-120	-	-	-	S	-	-	-	Tetratricopeptide repeat
NPEPGNMH_02677	2.08e-197	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
NPEPGNMH_02678	1.53e-72	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	ArsR family transcriptional regulator
NPEPGNMH_02679	2.56e-104	cadI	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPEPGNMH_02680	7.13e-233	arsB	-	-	P	ko:K03325	-	ko00000,ko02000	Arsenic resistance protein
NPEPGNMH_02681	9.82e-101	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Catalyzes the reduction of arsenate As(V) to arsenite As(III)
NPEPGNMH_02682	0.0	-	-	-	L	ko:K06400	-	ko00000	Recombinase
NPEPGNMH_02683	1.19e-46	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPEPGNMH_02684	2.8e-16	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPEPGNMH_02685	2.53e-97	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
NPEPGNMH_02686	9.38e-171	-	-	-	-	-	-	-	-
NPEPGNMH_02687	1.94e-218	yqeC	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase
NPEPGNMH_02688	1.31e-58	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
NPEPGNMH_02689	7.45e-180	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
NPEPGNMH_02690	2.24e-182	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NPEPGNMH_02692	8.31e-78	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
NPEPGNMH_02693	4.78e-273	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NPEPGNMH_02694	8.44e-201	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NPEPGNMH_02695	8.95e-61	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
NPEPGNMH_02696	2.47e-141	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NPEPGNMH_02697	4.81e-133	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
NPEPGNMH_02698	9.76e-82	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NPEPGNMH_02699	9.8e-179	yqeM	-	-	Q	-	-	-	Methyltransferase
NPEPGNMH_02700	2.69e-189	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NPEPGNMH_02701	6.65e-138	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
NPEPGNMH_02702	3.25e-137	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
NPEPGNMH_02703	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
NPEPGNMH_02704	2.36e-22	-	-	-	S	-	-	-	YqzM-like protein
NPEPGNMH_02705	2.01e-244	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
NPEPGNMH_02706	4e-49	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
NPEPGNMH_02707	4.16e-259	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NPEPGNMH_02708	9.53e-284	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
NPEPGNMH_02709	6.28e-73	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
NPEPGNMH_02710	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NPEPGNMH_02711	4.3e-278	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
NPEPGNMH_02712	1.65e-241	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NPEPGNMH_02713	4.36e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NPEPGNMH_02714	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
NPEPGNMH_02715	3.41e-257	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NPEPGNMH_02716	5.63e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
NPEPGNMH_02717	1.01e-180	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NPEPGNMH_02718	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
NPEPGNMH_02719	3.45e-202	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
NPEPGNMH_02720	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
NPEPGNMH_02721	2.25e-90	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
NPEPGNMH_02722	7.97e-292	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
NPEPGNMH_02723	4.35e-192	yqfA	-	-	S	-	-	-	UPF0365 protein
NPEPGNMH_02724	3.13e-79	yqfB	-	-	-	-	-	-	-
NPEPGNMH_02725	2.07e-60	yqfC	-	-	S	-	-	-	sporulation protein YqfC
NPEPGNMH_02726	1.04e-242	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
NPEPGNMH_02727	2.47e-224	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
NPEPGNMH_02729	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
NPEPGNMH_02730	8.68e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NPEPGNMH_02731	1.42e-81	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
NPEPGNMH_02732	6.71e-93	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NPEPGNMH_02733	9.98e-215	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NPEPGNMH_02734	5.29e-27	-	-	-	S	-	-	-	YqzL-like protein
NPEPGNMH_02735	5.26e-187	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
NPEPGNMH_02736	2.12e-222	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
NPEPGNMH_02737	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
NPEPGNMH_02738	3.29e-144	ccpN	-	-	K	-	-	-	CBS domain
NPEPGNMH_02739	6.38e-191	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NPEPGNMH_02740	6.03e-114	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
NPEPGNMH_02741	5.12e-240	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NPEPGNMH_02742	5.09e-173	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NPEPGNMH_02743	2.79e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NPEPGNMH_02744	1.61e-81	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
NPEPGNMH_02745	2.41e-150	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
NPEPGNMH_02746	2.27e-270	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NPEPGNMH_02747	8.66e-227	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NPEPGNMH_02748	4.89e-58	yqfQ	-	-	S	-	-	-	YqfQ-like protein
NPEPGNMH_02749	5.42e-311	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NPEPGNMH_02750	1.04e-214	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NPEPGNMH_02751	3.01e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
NPEPGNMH_02752	3.83e-199	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
NPEPGNMH_02753	8.59e-107	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
NPEPGNMH_02754	8.25e-142	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
NPEPGNMH_02755	2.04e-81	yqfX	-	-	S	-	-	-	membrane
NPEPGNMH_02756	5.22e-257	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NPEPGNMH_02757	2.84e-63	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
NPEPGNMH_02758	2.05e-99	yqgA	-	-	-	-	-	-	-
NPEPGNMH_02759	9.27e-172	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
NPEPGNMH_02760	8.25e-101	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
NPEPGNMH_02761	1.59e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
NPEPGNMH_02762	3.96e-293	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
NPEPGNMH_02763	2.6e-67	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
NPEPGNMH_02764	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
NPEPGNMH_02765	4.51e-206	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
NPEPGNMH_02766	7.43e-205	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
NPEPGNMH_02767	5.26e-202	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
NPEPGNMH_02768	2.4e-190	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NPEPGNMH_02769	2.71e-187	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NPEPGNMH_02770	2.92e-98	yqzC	-	-	S	-	-	-	YceG-like family
NPEPGNMH_02771	3.42e-68	yqzD	-	-	-	-	-	-	-
NPEPGNMH_02773	1.24e-260	yqgM	2.4.1.250	-	M	ko:K15521	-	ko00000,ko01000	Glycosyl transferases group 1
NPEPGNMH_02774	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
NPEPGNMH_02775	2.38e-138	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NPEPGNMH_02776	3.38e-14	yqgO	-	-	-	-	-	-	-
NPEPGNMH_02777	0.0	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
NPEPGNMH_02778	2.19e-44	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
NPEPGNMH_02779	2.81e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
NPEPGNMH_02780	0.0	yqgS	2.7.8.20	-	M	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
NPEPGNMH_02781	1.06e-283	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
NPEPGNMH_02782	5.65e-258	yqgU	-	-	-	-	-	-	-
NPEPGNMH_02783	7.34e-66	yqgV	-	-	S	-	-	-	Thiamine-binding protein
NPEPGNMH_02784	1.91e-31	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
NPEPGNMH_02785	5.52e-158	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
NPEPGNMH_02786	1.46e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
NPEPGNMH_02787	7.79e-85	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
NPEPGNMH_02789	1.06e-193	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NPEPGNMH_02790	6.17e-64	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
NPEPGNMH_02791	2.93e-225	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
NPEPGNMH_02792	1.51e-233	yqxL	-	-	P	-	-	-	Mg2 transporter protein
NPEPGNMH_02794	9.05e-257	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NPEPGNMH_02795	1.29e-220	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
NPEPGNMH_02796	5.33e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
NPEPGNMH_02797	9.7e-94	gspH	-	-	NU	ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02035,ko02044	protein transport across the cell outer membrane
NPEPGNMH_02798	4.35e-79	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
NPEPGNMH_02799	3.44e-65	comGF	-	-	U	ko:K02246,ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
NPEPGNMH_02800	2.55e-55	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
NPEPGNMH_02801	4.9e-37	yqzE	-	-	S	-	-	-	YqzE-like protein
NPEPGNMH_02802	6.36e-71	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
NPEPGNMH_02803	8.73e-160	yqxM	-	-	-	ko:K19433	-	ko00000	-
NPEPGNMH_02804	7.4e-98	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
NPEPGNMH_02805	1.56e-182	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
NPEPGNMH_02806	3.69e-72	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
NPEPGNMH_02807	4.84e-34	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
NPEPGNMH_02808	9.14e-197	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
NPEPGNMH_02809	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
NPEPGNMH_02810	8.13e-263	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
NPEPGNMH_02811	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NPEPGNMH_02812	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NPEPGNMH_02813	7.5e-83	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
NPEPGNMH_02814	1.12e-204	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NPEPGNMH_02815	1.97e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
NPEPGNMH_02816	1.21e-210	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
NPEPGNMH_02817	5.18e-81	yqhP	-	-	-	-	-	-	-
NPEPGNMH_02818	3.79e-223	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
NPEPGNMH_02819	8.02e-121	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
NPEPGNMH_02820	1.17e-101	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
NPEPGNMH_02821	3.65e-250	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
NPEPGNMH_02822	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NPEPGNMH_02823	6.96e-50	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
NPEPGNMH_02824	1.22e-218	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
NPEPGNMH_02825	6.93e-112	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
NPEPGNMH_02826	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
NPEPGNMH_02827	1.93e-77	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
NPEPGNMH_02828	7.65e-257	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
NPEPGNMH_02829	1.28e-131	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
NPEPGNMH_02830	9.25e-150	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
NPEPGNMH_02831	9.92e-135	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
NPEPGNMH_02832	3.21e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NPEPGNMH_02833	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NPEPGNMH_02834	1.65e-88	yqhY	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_02835	4.8e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NPEPGNMH_02836	1.07e-200	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NPEPGNMH_02837	2.5e-312	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NPEPGNMH_02838	1.35e-45	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NPEPGNMH_02839	4.2e-209	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NPEPGNMH_02840	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NPEPGNMH_02841	1.77e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
NPEPGNMH_02842	3.75e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NPEPGNMH_02843	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
NPEPGNMH_02844	1.26e-303	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
NPEPGNMH_02845	1.89e-186	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
NPEPGNMH_02847	1.77e-276	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NPEPGNMH_02848	2.26e-37	-	-	-	-	-	-	-	-
NPEPGNMH_02849	5.67e-139	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
NPEPGNMH_02850	3.68e-172	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
NPEPGNMH_02851	5.7e-281	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
NPEPGNMH_02852	7.2e-201	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
NPEPGNMH_02853	5.16e-270	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
NPEPGNMH_02854	1.66e-267	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
NPEPGNMH_02855	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
NPEPGNMH_02856	1.07e-209	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NPEPGNMH_02857	1.56e-46	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
NPEPGNMH_02858	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
NPEPGNMH_02859	6.35e-201	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
NPEPGNMH_02860	1.92e-262	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
NPEPGNMH_02861	1.18e-255	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
NPEPGNMH_02862	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NPEPGNMH_02863	1.92e-238	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NPEPGNMH_02864	6.92e-235	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NPEPGNMH_02865	1.57e-296	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NPEPGNMH_02866	6.38e-195	-	-	-	K	ko:K19575	-	ko00000,ko00002,ko03000	helix_turn_helix, mercury resistance
NPEPGNMH_02867	3.09e-267	norA	-	-	EGP	ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
NPEPGNMH_02868	3.47e-115	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NPEPGNMH_02869	2.36e-80	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NPEPGNMH_02870	3.79e-101	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
NPEPGNMH_02871	1.43e-175	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
NPEPGNMH_02872	8.94e-143	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
NPEPGNMH_02873	1.28e-166	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
NPEPGNMH_02874	9.33e-226	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
NPEPGNMH_02875	2.41e-128	yqjB	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_02877	7.17e-99	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
NPEPGNMH_02878	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NPEPGNMH_02879	5.26e-259	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
NPEPGNMH_02880	8.77e-184	yqjF	-	-	S	ko:K09166	-	ko00000	Uncharacterized conserved protein (COG2071)
NPEPGNMH_02881	3.36e-184	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NPEPGNMH_02882	1.77e-32	yqzJ	-	-	-	-	-	-	-
NPEPGNMH_02883	2.72e-301	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NPEPGNMH_02884	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NPEPGNMH_02885	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NPEPGNMH_02886	7.66e-222	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NPEPGNMH_02887	3.86e-188	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NPEPGNMH_02888	1.21e-245	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NPEPGNMH_02889	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
NPEPGNMH_02890	6.84e-190	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NPEPGNMH_02891	3.98e-230	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
NPEPGNMH_02892	3.41e-185	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
NPEPGNMH_02893	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
NPEPGNMH_02894	6.6e-229	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
NPEPGNMH_02895	1.33e-95	yqjT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPEPGNMH_02897	1.08e-289	yqjV	-	-	G	-	-	-	Major Facilitator Superfamily
NPEPGNMH_02899	4.03e-304	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NPEPGNMH_02900	1.87e-65	yqiX	-	-	S	-	-	-	YolD-like protein
NPEPGNMH_02901	5.46e-113	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
NPEPGNMH_02902	5.51e-79	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
NPEPGNMH_02903	2.89e-251	yqkA	-	-	K	-	-	-	GrpB protein
NPEPGNMH_02904	6.17e-73	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
NPEPGNMH_02905	1.12e-53	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
NPEPGNMH_02906	4.29e-227	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
NPEPGNMH_02907	1.78e-29	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
NPEPGNMH_02908	9.26e-218	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
NPEPGNMH_02909	8.21e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
NPEPGNMH_02910	4.07e-120	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
NPEPGNMH_02911	2.73e-96	yqxK	-	-	L	-	-	-	DNA helicase
NPEPGNMH_02912	1.96e-170	yqxK	-	-	L	-	-	-	DNA helicase
NPEPGNMH_02913	3.18e-77	ansR	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_02914	2.38e-81	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
NPEPGNMH_02915	3.97e-146	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
NPEPGNMH_02916	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
NPEPGNMH_02917	0.0	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
NPEPGNMH_02918	3.95e-309	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
NPEPGNMH_02919	3.73e-44	yqkK	-	-	-	-	-	-	-
NPEPGNMH_02920	1.96e-139	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
NPEPGNMH_02921	2.26e-104	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
NPEPGNMH_02922	2.73e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
NPEPGNMH_02923	3.91e-214	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
NPEPGNMH_02924	2.89e-295	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NPEPGNMH_02925	1.6e-55	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NPEPGNMH_02926	1.76e-117	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NPEPGNMH_02927	2.89e-272	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NPEPGNMH_02928	1.98e-76	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
NPEPGNMH_02929	6.78e-100	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
NPEPGNMH_02930	1.18e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPEPGNMH_02931	5.72e-144	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
NPEPGNMH_02932	5.43e-90	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
NPEPGNMH_02933	6.71e-102	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
NPEPGNMH_02934	6.02e-246	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
NPEPGNMH_02935	2.15e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
NPEPGNMH_02936	1.85e-143	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
NPEPGNMH_02937	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
NPEPGNMH_02938	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NPEPGNMH_02939	2.67e-193	ypuA	-	-	S	-	-	-	Secreted protein
NPEPGNMH_02940	1.23e-105	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NPEPGNMH_02942	3.82e-09	-	-	-	S	-	-	-	SNARE associated Golgi protein
NPEPGNMH_02944	1.28e-45	ypzJ	-	-	S	ko:K07069	-	ko00000	nucleic-acid-binding protein containing a Zn-ribbon domain
NPEPGNMH_02945	1.18e-132	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NPEPGNMH_02946	2.96e-72	ypuD	-	-	-	-	-	-	-
NPEPGNMH_02947	1.77e-261	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NPEPGNMH_02948	1.24e-147	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
NPEPGNMH_02949	2.96e-268	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NPEPGNMH_02950	8.41e-107	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NPEPGNMH_02951	1.12e-83	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPEPGNMH_02952	3.34e-93	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
NPEPGNMH_02953	1.33e-167	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NPEPGNMH_02954	2e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NPEPGNMH_02955	6.13e-128	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
NPEPGNMH_02956	4.11e-273	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NPEPGNMH_02957	7.57e-135	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
NPEPGNMH_02958	8.62e-114	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
NPEPGNMH_02959	4.45e-169	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NPEPGNMH_02960	1.5e-128	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
NPEPGNMH_02961	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
NPEPGNMH_02962	4.67e-279	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
NPEPGNMH_02963	3.62e-45	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPEPGNMH_02964	9.45e-111	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPEPGNMH_02965	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NPEPGNMH_02966	1.08e-133	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NPEPGNMH_02967	2.7e-257	rsiX	-	-	-	-	-	-	-
NPEPGNMH_02968	2.89e-175	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NPEPGNMH_02969	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPEPGNMH_02970	6.3e-117	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NPEPGNMH_02971	8.35e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
NPEPGNMH_02972	5.67e-258	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
NPEPGNMH_02973	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
NPEPGNMH_02974	6.13e-129	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
NPEPGNMH_02975	1.48e-22	ypbE	-	-	M	-	-	-	Lysin motif
NPEPGNMH_02976	6.55e-101	ypbE	-	-	M	-	-	-	Lysin motif
NPEPGNMH_02977	1.42e-106	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
NPEPGNMH_02978	4.33e-188	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
NPEPGNMH_02979	5.56e-136	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NPEPGNMH_02980	1.42e-308	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
NPEPGNMH_02981	1.62e-227	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
NPEPGNMH_02982	4.33e-154	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
NPEPGNMH_02983	4.88e-208	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
NPEPGNMH_02984	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
NPEPGNMH_02985	4.63e-144	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
NPEPGNMH_02986	1.74e-32	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
NPEPGNMH_02987	1.73e-147	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
NPEPGNMH_02988	9.5e-263	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
NPEPGNMH_02989	1.02e-192	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NPEPGNMH_02990	1.13e-11	-	-	-	S	-	-	-	YpzI-like protein
NPEPGNMH_02991	2.73e-134	yphA	-	-	-	-	-	-	-
NPEPGNMH_02992	2.19e-34	yphB	-	-	S	ko:K05739	-	ko00000	YIEGIA protein
NPEPGNMH_02993	1.8e-142	yphB	-	-	S	ko:K05739	-	ko00000	YIEGIA protein
NPEPGNMH_02994	8.69e-40	ypzH	-	-	-	-	-	-	-
NPEPGNMH_02995	4.77e-316	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
NPEPGNMH_02996	2.01e-243	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
NPEPGNMH_02997	7.09e-27	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
NPEPGNMH_02998	9.07e-178	yphF	-	-	-	-	-	-	-
NPEPGNMH_02999	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NPEPGNMH_03000	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NPEPGNMH_03001	4.41e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
NPEPGNMH_03002	7.74e-46	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
NPEPGNMH_03003	8.72e-178	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
NPEPGNMH_03004	1.34e-169	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NPEPGNMH_03005	4.09e-249	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NPEPGNMH_03006	2.17e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NPEPGNMH_03007	3.69e-183	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
NPEPGNMH_03008	1.44e-277	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NPEPGNMH_03009	8.48e-265	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NPEPGNMH_03010	9.82e-84	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
NPEPGNMH_03011	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NPEPGNMH_03012	6.08e-230	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NPEPGNMH_03013	4.18e-145	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
NPEPGNMH_03014	2.82e-153	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
NPEPGNMH_03015	9.33e-295	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NPEPGNMH_03016	3.82e-186	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NPEPGNMH_03017	4.5e-259	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NPEPGNMH_03018	1.71e-264	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
NPEPGNMH_03019	9.91e-302	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NPEPGNMH_03020	5.27e-299	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
NPEPGNMH_03021	1.29e-129	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
NPEPGNMH_03022	4.75e-101	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
NPEPGNMH_03023	3.35e-126	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
NPEPGNMH_03024	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
NPEPGNMH_03025	5.71e-191	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
NPEPGNMH_03026	1.63e-125	ypjA	-	-	S	-	-	-	membrane
NPEPGNMH_03027	6.84e-183	ypjB	-	-	S	-	-	-	sporulation protein
NPEPGNMH_03028	6.06e-145	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
NPEPGNMH_03029	2.47e-74	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
NPEPGNMH_03030	8.38e-190	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NPEPGNMH_03031	1.52e-94	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
NPEPGNMH_03032	5.52e-14	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
NPEPGNMH_03033	5.56e-141	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
NPEPGNMH_03034	1.04e-268	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
NPEPGNMH_03035	1.41e-283	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NPEPGNMH_03036	4.87e-234	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NPEPGNMH_03037	4.85e-194	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NPEPGNMH_03038	1.34e-200	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NPEPGNMH_03039	4.16e-85	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NPEPGNMH_03040	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
NPEPGNMH_03041	1.52e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
NPEPGNMH_03042	2.27e-103	ypmB	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_03043	1.07e-285	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
NPEPGNMH_03044	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
NPEPGNMH_03045	6.62e-165	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
NPEPGNMH_03046	3.57e-158	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NPEPGNMH_03047	1.43e-121	ypoC	-	-	-	-	-	-	-
NPEPGNMH_03048	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
NPEPGNMH_03049	3.2e-150	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NPEPGNMH_03050	4.54e-241	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
NPEPGNMH_03053	7.9e-10	yppE	-	-	S	-	-	-	Bacterial domain of unknown function (DUF1798)
NPEPGNMH_03054	9.21e-11	-	-	-	S	-	-	-	YppF-like protein
NPEPGNMH_03055	8.72e-68	yppG	-	-	S	-	-	-	YppG-like protein
NPEPGNMH_03056	9.98e-92	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
NPEPGNMH_03057	1.34e-112	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
NPEPGNMH_03058	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
NPEPGNMH_03059	7.21e-301	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
NPEPGNMH_03060	1.14e-135	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
NPEPGNMH_03061	2.97e-60	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NPEPGNMH_03062	1.22e-81	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
NPEPGNMH_03063	1.71e-179	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
NPEPGNMH_03065	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
NPEPGNMH_03066	2.05e-179	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPEPGNMH_03067	1.25e-204	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NPEPGNMH_03068	1.71e-169	kdgR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
NPEPGNMH_03069	5.07e-44	kdgR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
NPEPGNMH_03070	6.95e-238	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
NPEPGNMH_03071	2.53e-133	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
NPEPGNMH_03072	1e-224	kdgT	-	-	P	ko:K02526	-	ko00000,ko02000	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
NPEPGNMH_03073	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NPEPGNMH_03074	8.16e-129	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NPEPGNMH_03075	3.14e-294	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
NPEPGNMH_03076	4.55e-266	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
NPEPGNMH_03077	3.33e-113	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
NPEPGNMH_03078	0.0	ypbR	-	-	S	-	-	-	Dynamin family
NPEPGNMH_03079	4.07e-52	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
NPEPGNMH_03080	1.08e-11	-	-	-	-	-	-	-	-
NPEPGNMH_03081	2.26e-213	ypcP	-	-	L	-	-	-	5'3' exonuclease
NPEPGNMH_03082	5.23e-05	-	-	-	-	ko:K06429	-	ko00000	-
NPEPGNMH_03083	1.6e-89	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
NPEPGNMH_03084	2.4e-138	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NPEPGNMH_03085	4e-163	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
NPEPGNMH_03086	1.54e-37	ypeQ	-	-	S	-	-	-	Zinc-finger
NPEPGNMH_03087	1.05e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
NPEPGNMH_03088	1.17e-22	degR	-	-	-	-	-	-	-
NPEPGNMH_03089	2.54e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
NPEPGNMH_03090	1.28e-276	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
NPEPGNMH_03091	1.28e-226	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NPEPGNMH_03092	1.89e-115	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
NPEPGNMH_03093	2.52e-142	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
NPEPGNMH_03094	8.52e-206	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
NPEPGNMH_03095	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
NPEPGNMH_03096	9.69e-99	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
NPEPGNMH_03097	6.15e-187	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
NPEPGNMH_03098	3.47e-148	ypjP	-	-	S	-	-	-	YpjP-like protein
NPEPGNMH_03099	8.91e-121	ltrC	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
NPEPGNMH_03100	7.27e-203	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NPEPGNMH_03101	1.21e-124	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NPEPGNMH_03102	1.71e-145	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NPEPGNMH_03103	8.03e-143	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
NPEPGNMH_03104	1.4e-236	yplP	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_03105	3.64e-310	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NPEPGNMH_03106	1.28e-54	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
NPEPGNMH_03107	3.83e-54	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
NPEPGNMH_03108	6.62e-21	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
NPEPGNMH_03109	1.28e-178	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NPEPGNMH_03110	4.27e-65	ypmS	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_03111	4.47e-37	ypmT	-	-	S	-	-	-	Uncharacterized ympT
NPEPGNMH_03112	3.49e-290	mepA	-	-	V	-	-	-	MATE efflux family protein
NPEPGNMH_03113	4.14e-94	ypoP	-	-	K	-	-	-	transcriptional
NPEPGNMH_03114	8.41e-134	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NPEPGNMH_03115	3.52e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
NPEPGNMH_03116	1.76e-124	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
NPEPGNMH_03117	0.0	yokA	-	-	L	-	-	-	Recombinase
NPEPGNMH_03118	4.93e-153	-	-	-	-	-	-	-	-
NPEPGNMH_03119	5.1e-123	-	-	-	-	-	-	-	-
NPEPGNMH_03122	8.79e-199	yokD	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	aminoglycoside
NPEPGNMH_03123	6.83e-109	-	-	-	S	-	-	-	Bacterial PH domain
NPEPGNMH_03124	2.55e-178	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
NPEPGNMH_03125	5.27e-261	-	-	-	-	-	-	-	-
NPEPGNMH_03126	2.64e-119	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
NPEPGNMH_03127	0.0	-	-	-	UW	ko:K21487,ko:K21489,ko:K21491,ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
NPEPGNMH_03128	9.26e-123	-	-	-	S	ko:K21490	-	ko00000,ko02048	SMI1 / KNR4 family (SUKH-1)
NPEPGNMH_03129	5.38e-142	yokK	-	-	S	-	-	-	SMI1 / KNR4 family
NPEPGNMH_03130	5.26e-128	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NPEPGNMH_03134	7.43e-49	-	-	-	-	-	-	-	-
NPEPGNMH_03135	7.69e-73	-	-	-	S	-	-	-	YolD-like protein
NPEPGNMH_03136	2.97e-306	-	-	-	S	-	-	-	damaged DNA binding
NPEPGNMH_03139	2.08e-246	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	Peptidase C39 family
NPEPGNMH_03140	2.53e-198	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	Peptidase C39 family
NPEPGNMH_03141	3.44e-91	-	-	-	CO	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	cell redox homeostasis
NPEPGNMH_03142	6.04e-309	-	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
NPEPGNMH_03143	3.04e-53	-	-	-	S	-	-	-	SPP1 phage holin
NPEPGNMH_03144	1.42e-43	bhlA	-	-	S	-	-	-	BhlA holin family
NPEPGNMH_03145	7.44e-257	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	Ami_2
NPEPGNMH_03147	1.31e-210	-	-	-	-	-	-	-	-
NPEPGNMH_03148	0.0	XK27_08080	-	-	G	-	-	-	Exopolysaccharide biosynthesis protein
NPEPGNMH_03149	9.28e-166	-	-	-	-	-	-	-	-
NPEPGNMH_03150	0.0	-	-	-	S	-	-	-	Pfam Transposase IS66
NPEPGNMH_03151	1.7e-186	-	-	-	S	-	-	-	Phage tail protein
NPEPGNMH_03152	0.0	-	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NPEPGNMH_03153	5.66e-159	-	-	-	-	-	-	-	-
NPEPGNMH_03158	3.06e-237	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NPEPGNMH_03159	4.16e-112	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
NPEPGNMH_03160	1.76e-163	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
NPEPGNMH_03161	1.71e-109	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NPEPGNMH_03162	1.63e-241	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NPEPGNMH_03163	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
NPEPGNMH_03164	1.46e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NPEPGNMH_03165	2.14e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NPEPGNMH_03166	5.48e-31	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NPEPGNMH_03167	5.51e-13	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NPEPGNMH_03168	4.61e-140	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NPEPGNMH_03169	3.2e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
NPEPGNMH_03170	3e-167	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NPEPGNMH_03171	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NPEPGNMH_03172	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NPEPGNMH_03174	6.93e-88	-	-	-	KL	ko:K06919	-	ko00000	Phage plasmid primase P4 family
NPEPGNMH_03175	0.0	dcm	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	DNA (cytosine-5-)-methyltransferase activity
NPEPGNMH_03176	1.43e-297	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
NPEPGNMH_03178	3.67e-254	-	-	-	V	-	-	-	AAA domain (dynein-related subfamily)
NPEPGNMH_03179	0.0	-	-	-	J	-	-	-	LlaJI restriction endonuclease
NPEPGNMH_03180	3.73e-11	ydjC	-	-	S	-	-	-	Abhydrolase domain containing 18
NPEPGNMH_03181	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
NPEPGNMH_03182	1.06e-258	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
NPEPGNMH_03183	0.0	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
NPEPGNMH_03184	5.39e-224	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
NPEPGNMH_03185	5.36e-148	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
NPEPGNMH_03186	1.04e-227	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NPEPGNMH_03187	3.96e-177	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
NPEPGNMH_03188	1.79e-203	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
NPEPGNMH_03189	1.37e-248	-	-	-	S	-	-	-	Ion transport 2 domain protein
NPEPGNMH_03190	0.0	iolT	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NPEPGNMH_03191	3.5e-249	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
NPEPGNMH_03192	1.79e-84	ydjM	-	-	M	-	-	-	Lytic transglycolase
NPEPGNMH_03193	3.76e-213	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
NPEPGNMH_03194	8.2e-48	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
NPEPGNMH_03195	3.21e-205	-	-	-	I	-	-	-	Alpha/beta hydrolase family
NPEPGNMH_03196	1.9e-233	yeaA	-	-	S	-	-	-	Protein of unknown function (DUF4003)
NPEPGNMH_03197	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
NPEPGNMH_03198	0.0	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
NPEPGNMH_03199	6.13e-199	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NPEPGNMH_03200	1.18e-227	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
NPEPGNMH_03201	6.74e-287	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NPEPGNMH_03202	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
NPEPGNMH_03203	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
NPEPGNMH_03204	1.2e-283	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
NPEPGNMH_03205	1.44e-165	yebC	-	-	M	-	-	-	Membrane
NPEPGNMH_03207	2.66e-120	yebE	-	-	S	-	-	-	UPF0316 protein
NPEPGNMH_03208	3.13e-38	yebG	-	-	S	-	-	-	NETI protein
NPEPGNMH_03209	2.28e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NPEPGNMH_03210	9.39e-278	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NPEPGNMH_03211	6.85e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NPEPGNMH_03212	1.06e-170	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
NPEPGNMH_03213	3.79e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPEPGNMH_03214	1.15e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPEPGNMH_03215	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPEPGNMH_03216	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NPEPGNMH_03217	4.2e-241	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
NPEPGNMH_03218	4.4e-138	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NPEPGNMH_03219	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
NPEPGNMH_03220	2.07e-300	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
NPEPGNMH_03221	5.26e-96	-	-	-	K	-	-	-	helix_turn_helix ASNC type
NPEPGNMH_03222	1.91e-297	-	-	-	E	ko:K16263	-	ko00000,ko02000	Amino acid permease
NPEPGNMH_03223	3.45e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
NPEPGNMH_03224	6.38e-22	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
NPEPGNMH_03225	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
NPEPGNMH_03226	7.03e-246	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
NPEPGNMH_03227	7.62e-68	yerC	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_03228	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
NPEPGNMH_03230	1.1e-161	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NPEPGNMH_03231	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
NPEPGNMH_03232	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NPEPGNMH_03233	1.77e-281	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
NPEPGNMH_03234	6.28e-253	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
NPEPGNMH_03235	2.29e-160	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
NPEPGNMH_03236	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NPEPGNMH_03237	7.37e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NPEPGNMH_03238	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NPEPGNMH_03239	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NPEPGNMH_03240	2.93e-201	yerO	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_03241	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NPEPGNMH_03242	1.8e-218	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NPEPGNMH_03243	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NPEPGNMH_03244	3.63e-127	-	-	-	L	-	-	-	Recombinase
NPEPGNMH_03245	5.61e-71	-	-	-	L	-	-	-	Resolvase, N terminal domain
NPEPGNMH_03246	0.0	yeeA	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
NPEPGNMH_03247	0.0	-	-	-	L	-	-	-	DEAD-like helicases superfamily
NPEPGNMH_03248	1.37e-271	yeeC	-	-	P	-	-	-	T5orf172
NPEPGNMH_03249	7.48e-05	-	-	-	-	-	-	-	-
NPEPGNMH_03250	4.15e-42	-	-	-	S	-	-	-	Colicin immunity protein / pyocin immunity protein
NPEPGNMH_03251	2.1e-109	-	-	-	S	-	-	-	Protein of unknown function, DUF600
NPEPGNMH_03252	0.0	-	-	-	L	-	-	-	nucleic acid phosphodiester bond hydrolysis
NPEPGNMH_03253	1.73e-246	-	3.4.24.40	-	CO	ko:K01406	ko01503,map01503	ko00000,ko00001,ko01000,ko01002	amine dehydrogenase activity
NPEPGNMH_03254	1.33e-275	rapH	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
NPEPGNMH_03256	1.09e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
NPEPGNMH_03258	1.86e-134	dhaR3	-	-	K	ko:K16137	-	ko00000,ko03000	Transcriptional regulator
NPEPGNMH_03259	4.95e-107	yesE	-	-	S	ko:K06893	-	ko00000	SnoaL-like domain
NPEPGNMH_03260	8.81e-206	yesF	-	-	GM	-	-	-	NAD(P)H-binding
NPEPGNMH_03261	3.8e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
NPEPGNMH_03262	2.31e-61	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
NPEPGNMH_03263	1.04e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
NPEPGNMH_03264	1.76e-132	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
NPEPGNMH_03266	3.52e-135	yesL	-	-	S	-	-	-	Protein of unknown function, DUF624
NPEPGNMH_03267	0.0	yesM	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NPEPGNMH_03268	5.07e-260	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
NPEPGNMH_03269	8.76e-316	yesO	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NPEPGNMH_03270	2.02e-218	yesP	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NPEPGNMH_03271	1.31e-212	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NPEPGNMH_03272	6.85e-255	-	3.2.1.172	GH105	S	ko:K15532	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
NPEPGNMH_03273	0.0	yesS	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_03274	3.56e-171	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NPEPGNMH_03275	1.41e-169	yesU	-	-	S	-	-	-	Domain of unknown function (DUF1961)
NPEPGNMH_03276	3.44e-146	-	-	-	S	-	-	-	Protein of unknown function, DUF624
NPEPGNMH_03277	0.0	-	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
NPEPGNMH_03278	0.0	yesX	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
NPEPGNMH_03279	9.13e-160	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NPEPGNMH_03280	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
NPEPGNMH_03281	0.0	yetA	-	-	-	-	-	-	-
NPEPGNMH_03282	1.73e-67	yetA	-	-	-	-	-	-	-
NPEPGNMH_03283	0.0	lplA	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NPEPGNMH_03284	1.01e-227	lplB	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
NPEPGNMH_03285	7.85e-209	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NPEPGNMH_03286	0.0	-	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
NPEPGNMH_03287	3.13e-158	yetF	-	-	S	-	-	-	membrane
NPEPGNMH_03288	4.67e-73	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
NPEPGNMH_03289	2.47e-85	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPEPGNMH_03290	9.79e-45	-	-	-	-	-	-	-	-
NPEPGNMH_03291	3.87e-114	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NPEPGNMH_03292	1.97e-54	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NPEPGNMH_03293	3.81e-28	yezD	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
NPEPGNMH_03294	2.55e-135	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
NPEPGNMH_03295	7.35e-203	-	-	-	EG	-	-	-	EamA-like transporter family
NPEPGNMH_03296	6.74e-117	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NPEPGNMH_03297	4.77e-270	yetM	-	-	CH	-	-	-	FAD binding domain
NPEPGNMH_03298	6.1e-255	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
NPEPGNMH_03299	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
NPEPGNMH_03300	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
NPEPGNMH_03301	2.15e-190	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
NPEPGNMH_03302	4.79e-220	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
NPEPGNMH_03303	9.79e-232	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
NPEPGNMH_03304	2.44e-286	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
NPEPGNMH_03305	2.84e-244	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
NPEPGNMH_03306	6.21e-268	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
NPEPGNMH_03307	9.43e-171	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
NPEPGNMH_03308	4.16e-313	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
NPEPGNMH_03309	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NPEPGNMH_03310	5.14e-161	yfmS	-	-	NT	-	-	-	chemotaxis protein
NPEPGNMH_03311	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NPEPGNMH_03312	6.48e-99	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
NPEPGNMH_03313	3.03e-91	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
NPEPGNMH_03314	3.59e-265	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
NPEPGNMH_03315	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NPEPGNMH_03316	1.86e-266	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
NPEPGNMH_03317	1.86e-107	yfmK	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	acetyltransferase
NPEPGNMH_03318	4.21e-242	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
NPEPGNMH_03319	1.06e-263	-	-	-	G	-	-	-	Major Facilitator Superfamily
NPEPGNMH_03320	0.0	pkn1	-	-	S	-	-	-	Sulfatase-modifying factor enzyme 1
NPEPGNMH_03321	1.4e-192	fhuC	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NPEPGNMH_03322	2.1e-223	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPEPGNMH_03323	2.85e-221	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPEPGNMH_03324	2.88e-221	yfmC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
NPEPGNMH_03325	1.06e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
NPEPGNMH_03326	1.71e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
NPEPGNMH_03327	2.45e-307	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
NPEPGNMH_03328	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
NPEPGNMH_03329	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
NPEPGNMH_03330	3.96e-154	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
NPEPGNMH_03331	1.45e-232	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
NPEPGNMH_03333	5.35e-288	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
NPEPGNMH_03334	7.21e-194	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
NPEPGNMH_03335	1.43e-277	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NPEPGNMH_03336	2.54e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
NPEPGNMH_03337	2.51e-159	yflK	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_03338	1.1e-25	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
NPEPGNMH_03339	5.42e-08	yflI	-	-	-	-	-	-	-
NPEPGNMH_03340	3.63e-66	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
NPEPGNMH_03341	1.14e-178	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
NPEPGNMH_03342	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NPEPGNMH_03343	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
NPEPGNMH_03344	1.89e-87	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
NPEPGNMH_03345	0.0	yflA	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
NPEPGNMH_03346	2.19e-249	yfkT	-	-	E	ko:K06309	-	ko00000	Spore germination protein
NPEPGNMH_03348	2.28e-271	yfkR	-	-	S	ko:K06297,ko:K06308	-	ko00000	spore germination
NPEPGNMH_03349	0.0	yfkQ	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
NPEPGNMH_03350	0.0	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NPEPGNMH_03351	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
NPEPGNMH_03352	1.24e-172	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
NPEPGNMH_03353	5.27e-161	frp	-	-	C	-	-	-	nitroreductase
NPEPGNMH_03354	0.0	yfkN	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
NPEPGNMH_03355	0.0	yfkN	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
NPEPGNMH_03356	8.44e-118	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
NPEPGNMH_03357	6.21e-266	ydiN3	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
NPEPGNMH_03358	7.27e-42	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
NPEPGNMH_03359	2.14e-110	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NPEPGNMH_03360	2.53e-67	yfkI	-	-	S	-	-	-	gas vesicle protein
NPEPGNMH_03361	9.64e-184	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
NPEPGNMH_03362	1.64e-12	-	-	-	-	-	-	-	-
NPEPGNMH_03363	1.9e-278	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
NPEPGNMH_03364	1.34e-235	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
NPEPGNMH_03365	3.69e-189	yfkD	-	-	S	-	-	-	YfkD-like protein
NPEPGNMH_03366	4.44e-191	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
NPEPGNMH_03367	1.76e-283	yfkA	-	-	S	-	-	-	YfkB-like domain
NPEPGNMH_03368	3.26e-36	yfjT	-	-	-	-	-	-	-
NPEPGNMH_03369	7.24e-198	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
NPEPGNMH_03370	4.82e-194	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NPEPGNMH_03371	7.8e-237	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
NPEPGNMH_03372	1.94e-214	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NPEPGNMH_03373	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NPEPGNMH_03374	3e-53	-	-	-	S	-	-	-	YfzA-like protein
NPEPGNMH_03375	1.21e-243	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NPEPGNMH_03376	9.55e-111	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
NPEPGNMH_03378	1.36e-244	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NPEPGNMH_03379	2.75e-244	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NPEPGNMH_03380	4.19e-265	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NPEPGNMH_03381	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NPEPGNMH_03382	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
NPEPGNMH_03383	8.16e-36	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
NPEPGNMH_03384	7.42e-75	yfjF	-	-	S	ko:K09771	-	ko00000,ko02000	UPF0060 membrane protein
NPEPGNMH_03385	1.53e-104	-	-	-	S	-	-	-	Family of unknown function (DUF5381)
NPEPGNMH_03386	1.49e-131	yfjD	-	-	S	-	-	-	Family of unknown function (DUF5381)
NPEPGNMH_03387	2.5e-185	yfjC	-	-	-	-	-	-	-
NPEPGNMH_03388	1.94e-270	yfjB	-	-	-	-	-	-	-
NPEPGNMH_03389	5.59e-61	yfjA	-	-	S	-	-	-	Belongs to the WXG100 family
NPEPGNMH_03390	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NPEPGNMH_03391	6.12e-181	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
NPEPGNMH_03392	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NPEPGNMH_03393	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
NPEPGNMH_03394	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
NPEPGNMH_03395	2.01e-84	yfiD3	-	-	S	-	-	-	DoxX
NPEPGNMH_03396	7.28e-209	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
NPEPGNMH_03397	1.28e-228	-	-	-	K	ko:K02099	-	ko00000,ko03000	AraC-like ligand binding domain
NPEPGNMH_03398	0.0	yfiG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NPEPGNMH_03399	5.47e-234	-	-	-	G	-	-	-	Xylose isomerase
NPEPGNMH_03400	5.17e-295	-	-	-	S	-	-	-	Oxidoreductase
NPEPGNMH_03401	7.54e-276	baeS	-	-	T	-	-	-	Histidine kinase
NPEPGNMH_03402	1.05e-146	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
NPEPGNMH_03403	5.22e-209	drrA	-	-	V	ko:K01990,ko:K09695	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPGNMH_03404	3.66e-274	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NPEPGNMH_03405	4.56e-267	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
NPEPGNMH_03406	1.89e-128	padR	-	-	K	-	-	-	transcriptional
NPEPGNMH_03407	7.87e-128	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NPEPGNMH_03408	2.29e-253	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NPEPGNMH_03409	4.18e-141	yfiR	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_03410	4.51e-281	yfiS	-	-	EGP	-	-	-	Major facilitator superfamily
NPEPGNMH_03411	2.41e-129	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
NPEPGNMH_03412	0.0	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
NPEPGNMH_03413	5.39e-106	yfiV	-	-	K	-	-	-	transcriptional
NPEPGNMH_03414	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NPEPGNMH_03415	2.81e-233	yfiY	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
NPEPGNMH_03416	3.95e-216	yfiZ	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPEPGNMH_03417	5.18e-229	yfhA	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPEPGNMH_03418	7.61e-215	yfhB	-	-	S	-	-	-	PhzF family
NPEPGNMH_03419	2.87e-138	yfhC	-	-	C	-	-	-	nitroreductase
NPEPGNMH_03420	8.86e-35	yfhD	-	-	S	-	-	-	YfhD-like protein
NPEPGNMH_03422	1.13e-221	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
NPEPGNMH_03423	3.25e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
NPEPGNMH_03424	4.58e-69	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
NPEPGNMH_03426	2.45e-268	yfhI	-	-	EGP	-	-	-	-transporter
NPEPGNMH_03427	2.25e-27	sspK	-	-	S	ko:K06428	-	ko00000	reproduction
NPEPGNMH_03428	8.95e-60	yfhJ	-	-	S	-	-	-	WVELL protein
NPEPGNMH_03429	3.58e-119	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
NPEPGNMH_03430	5.4e-67	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
NPEPGNMH_03431	3.37e-219	yfhM	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha beta hydrolase
NPEPGNMH_03432	3.43e-236	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
NPEPGNMH_03433	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
NPEPGNMH_03434	7.22e-237	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
NPEPGNMH_03435	8.47e-268	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
NPEPGNMH_03436	1.73e-48	yfhS	-	-	-	-	-	-	-
NPEPGNMH_03437	3.13e-172	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPEPGNMH_03438	2.35e-14	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
NPEPGNMH_03439	1.88e-63	ygaB	-	-	S	-	-	-	YgaB-like protein
NPEPGNMH_03440	8.1e-136	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
NPEPGNMH_03441	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
NPEPGNMH_03442	1.87e-238	ygaE	-	-	S	-	-	-	Membrane
NPEPGNMH_03443	1.19e-314	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
NPEPGNMH_03444	2.92e-113	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
NPEPGNMH_03445	2.37e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
NPEPGNMH_03446	4.67e-75	ygzB	-	-	S	-	-	-	UPF0295 protein
NPEPGNMH_03447	8.23e-215	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
NPEPGNMH_03449	1.73e-247	-	-	-	A	-	-	-	Belongs to the 'phage' integrase family
NPEPGNMH_03450	2e-94	-	-	-	-	-	-	-	-
NPEPGNMH_03451	1.65e-112	-	-	-	-	-	-	-	-
NPEPGNMH_03454	8.1e-197	-	-	-	-	-	-	-	-
NPEPGNMH_03455	1.79e-17	-	-	-	-	-	-	-	-
NPEPGNMH_03456	2.22e-76	-	-	-	-	-	-	-	-
NPEPGNMH_03459	1.58e-145	-	-	-	-	-	-	-	-
NPEPGNMH_03460	2.4e-169	-	-	-	-	-	-	-	-
NPEPGNMH_03461	4.38e-118	-	-	-	-	-	-	-	-
NPEPGNMH_03462	9.48e-157	-	-	-	-	-	-	-	-
NPEPGNMH_03464	8.95e-91	-	-	-	-	-	-	-	-
NPEPGNMH_03465	8.05e-106	-	-	-	-	-	-	-	-
NPEPGNMH_03466	5.93e-237	-	-	-	-	-	-	-	-
NPEPGNMH_03467	1.24e-122	-	-	-	-	-	-	-	-
NPEPGNMH_03468	0.0	-	-	-	-	-	-	-	-
NPEPGNMH_03469	0.0	-	-	-	-	-	-	-	-
NPEPGNMH_03470	0.0	-	-	-	S	-	-	-	Terminase-like family
NPEPGNMH_03471	4.45e-225	-	-	-	-	-	-	-	-
NPEPGNMH_03474	2.29e-293	-	-	-	-	-	-	-	-
NPEPGNMH_03476	7.27e-56	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NPEPGNMH_03477	0.0	-	-	-	-	-	-	-	-
NPEPGNMH_03480	6.64e-73	bldD	-	-	K	ko:K07110,ko:K21572	-	ko00000,ko02000,ko03000	domain, Protein
NPEPGNMH_03483	1.07e-305	-	-	-	-	-	-	-	-
NPEPGNMH_03485	0.0	-	-	-	-	-	-	-	-
NPEPGNMH_03486	7.56e-48	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
NPEPGNMH_03487	0.0	-	-	-	-	-	-	-	-
NPEPGNMH_03493	2.68e-124	-	-	-	S	-	-	-	Super-infection exclusion protein B
NPEPGNMH_03494	8.39e-125	-	-	-	-	-	-	-	-
NPEPGNMH_03496	7.95e-135	-	-	-	-	-	-	-	-
NPEPGNMH_03501	1.61e-175	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NPEPGNMH_03502	2.93e-28	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NPEPGNMH_03503	0.0	-	-	-	S	-	-	-	DNA-sulfur modification-associated
NPEPGNMH_03504	2.89e-226	-	-	-	-	-	-	-	-
NPEPGNMH_03505	4.78e-46	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
NPEPGNMH_03510	0.000573	-	-	-	S	-	-	-	YopX protein
NPEPGNMH_03516	2.12e-175	-	-	-	S	ko:K07741	-	ko00000	Phage regulatory protein Rha (Phage_pRha)
NPEPGNMH_03517	2.65e-15	-	-	-	S	-	-	-	Protein of unknown function (DUF2815)
NPEPGNMH_03519	1.16e-102	yoqH	-	-	M	-	-	-	LysM domain
NPEPGNMH_03521	9.17e-126	-	-	-	S	-	-	-	Protein of unknown function (DUF1273)
NPEPGNMH_03523	3.88e-60	-	-	-	-	-	-	-	-
NPEPGNMH_03530	6.17e-103	-	-	-	-	-	-	-	-
NPEPGNMH_03531	3.73e-199	ligB	6.5.1.1, 6.5.1.6, 6.5.1.7	-	L	ko:K01971,ko:K10747	ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450	ko00000,ko00001,ko01000,ko03032,ko03400	ATP-dependent DNA ligase
NPEPGNMH_03532	2.62e-167	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
NPEPGNMH_03535	1.83e-192	-	-	-	S	-	-	-	Pfam:DUF867
NPEPGNMH_03536	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
NPEPGNMH_03541	2.37e-219	-	-	-	-	-	-	-	-
NPEPGNMH_03542	6.35e-229	-	-	-	L	-	-	-	AAA domain
NPEPGNMH_03543	1.1e-112	-	-	-	-	-	-	-	-
NPEPGNMH_03544	2.38e-277	-	-	-	J	-	-	-	DnaB-like helicase C terminal domain
NPEPGNMH_03545	7.26e-57	-	-	-	J	-	-	-	DnaB-like helicase C terminal domain
NPEPGNMH_03546	3.45e-288	-	-	-	L	-	-	-	DNA primase activity
NPEPGNMH_03547	0.0	-	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
NPEPGNMH_03548	0.0	-	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
NPEPGNMH_03549	9.54e-147	-	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_03554	3.92e-115	tmk	2.1.1.45, 2.7.4.9	-	F	ko:K00560,ko:K00943	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dTDP biosynthetic process
NPEPGNMH_03555	1.71e-126	yorS	-	-	S	-	-	-	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
NPEPGNMH_03557	0.0	ddeI	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	DNA (cytosine-5-)-methyltransferase activity
NPEPGNMH_03574	7.75e-87	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
NPEPGNMH_03575	1.71e-160	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPEPGNMH_03576	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPEPGNMH_03577	1.59e-139	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPEPGNMH_03578	3.73e-126	-	-	-	L	-	-	-	HNH endonuclease
NPEPGNMH_03579	1.12e-87	-	-	-	S	-	-	-	Ribonucleotide reductase, small chain
NPEPGNMH_03580	2.34e-51	-	-	-	O	-	-	-	Glutaredoxin
NPEPGNMH_03581	3.02e-101	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
NPEPGNMH_03582	2.85e-107	-	-	-	L	-	-	-	Bacterial transcription activator, effector binding domain
NPEPGNMH_03587	2.24e-41	-	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
NPEPGNMH_03588	6.52e-216	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NPEPGNMH_03597	1.31e-139	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NPEPGNMH_03599	1.13e-82	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
NPEPGNMH_03600	4.17e-282	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
NPEPGNMH_03601	2.95e-240	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
NPEPGNMH_03602	5.57e-86	cgeA	-	-	-	ko:K06319	-	ko00000	-
NPEPGNMH_03603	3.04e-59	cgeC	-	-	-	ko:K06321	-	ko00000	-
NPEPGNMH_03604	3.37e-296	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
NPEPGNMH_03605	2.06e-186	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
NPEPGNMH_03608	0.0	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NPEPGNMH_03610	9.44e-153	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NPEPGNMH_03611	3.62e-194	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
NPEPGNMH_03612	1.61e-94	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
NPEPGNMH_03613	9.5e-200	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
NPEPGNMH_03614	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
NPEPGNMH_03615	3.44e-63	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
NPEPGNMH_03616	7.3e-50	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
NPEPGNMH_03617	3.84e-161	yodN	-	-	-	-	-	-	-
NPEPGNMH_03619	5.18e-34	yozD	-	-	S	-	-	-	YozD-like protein
NPEPGNMH_03620	4.02e-138	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
NPEPGNMH_03621	1.17e-71	yodL	-	-	S	-	-	-	YodL-like
NPEPGNMH_03622	2.08e-12	-	-	-	-	-	-	-	-
NPEPGNMH_03623	1.19e-163	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
NPEPGNMH_03624	1.62e-190	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
NPEPGNMH_03625	2.93e-42	yodI	-	-	-	-	-	-	-
NPEPGNMH_03626	6.38e-168	yodH	-	-	Q	-	-	-	Methyltransferase
NPEPGNMH_03627	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
NPEPGNMH_03628	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NPEPGNMH_03629	2.36e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
NPEPGNMH_03630	1.18e-223	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
NPEPGNMH_03631	1.31e-146	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
NPEPGNMH_03632	1.92e-140	yodC	-	-	C	-	-	-	nitroreductase
NPEPGNMH_03633	1.37e-76	yodB	-	-	K	-	-	-	transcriptional
NPEPGNMH_03634	7.11e-59	iolK	-	-	S	-	-	-	tautomerase
NPEPGNMH_03635	1.01e-293	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
NPEPGNMH_03636	1.95e-14	-	-	-	-	-	-	-	-
NPEPGNMH_03637	6e-79	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
NPEPGNMH_03638	1.21e-209	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
NPEPGNMH_03639	1.85e-58	-	-	-	-	-	-	-	-
NPEPGNMH_03640	2.32e-79	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
NPEPGNMH_03641	1.84e-161	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
NPEPGNMH_03642	2.49e-194	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NPEPGNMH_03643	5.06e-314	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
NPEPGNMH_03645	3.69e-142	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NPEPGNMH_03646	5.62e-294	yojK	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
NPEPGNMH_03647	1.3e-267	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
NPEPGNMH_03648	2.1e-126	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NPEPGNMH_03649	1.33e-207	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
NPEPGNMH_03650	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
NPEPGNMH_03651	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
NPEPGNMH_03652	3.16e-265	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
NPEPGNMH_03653	3.31e-214	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
NPEPGNMH_03654	4.35e-300	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NPEPGNMH_03655	3.35e-212	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
NPEPGNMH_03656	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
NPEPGNMH_03657	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
NPEPGNMH_03658	1.91e-42	yozC	-	-	-	-	-	-	-
NPEPGNMH_03659	2.17e-74	yozO	-	-	S	-	-	-	Bacterial PH domain
NPEPGNMH_03660	1.83e-49	yocN	-	-	-	-	-	-	-
NPEPGNMH_03661	2.94e-55	yozN	-	-	-	-	-	-	-
NPEPGNMH_03662	6.6e-115	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
NPEPGNMH_03663	6.71e-36	-	-	-	-	-	-	-	-
NPEPGNMH_03664	3.02e-70	yocL	-	-	-	-	-	-	-
NPEPGNMH_03665	1.42e-107	yocK	-	-	T	-	-	-	general stress protein
NPEPGNMH_03666	1.46e-147	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NPEPGNMH_03667	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
NPEPGNMH_03668	2.89e-175	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
NPEPGNMH_03669	4.71e-135	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPEPGNMH_03670	1.22e-252	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NPEPGNMH_03671	3.99e-258	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
NPEPGNMH_03672	1.21e-243	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
NPEPGNMH_03673	1.32e-122	yocC	-	-	-	-	-	-	-
NPEPGNMH_03674	4.49e-186	-	-	-	-	-	-	-	-
NPEPGNMH_03675	1.21e-97	yozB	-	-	S	ko:K08976	-	ko00000	membrane
NPEPGNMH_03676	3.28e-157	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NPEPGNMH_03677	8.12e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
NPEPGNMH_03678	7.69e-123	yobW	-	-	-	-	-	-	-
NPEPGNMH_03679	2.05e-229	yobV	-	-	K	-	-	-	WYL domain
NPEPGNMH_03680	1.55e-114	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
NPEPGNMH_03681	1.34e-169	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
NPEPGNMH_03682	9.22e-129	yobS	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_03683	1.29e-183	-	-	-	J	-	-	-	FR47-like protein
NPEPGNMH_03684	5.23e-175	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
NPEPGNMH_03685	2.21e-72	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
NPEPGNMH_03686	0.0	yobO	-	-	M	-	-	-	Pectate lyase superfamily protein
NPEPGNMH_03687	0.0	iaaM	1.4.3.4	-	E	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	ko00000,ko00001,ko00002,ko01000	COG1231 Monoamine oxidase
NPEPGNMH_03688	4.3e-136	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
NPEPGNMH_03689	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NPEPGNMH_03690	6.69e-112	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
NPEPGNMH_03691	3.58e-202	-	-	-	-	-	-	-	-
NPEPGNMH_03692	0.0	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NPEPGNMH_03693	2.08e-64	-	-	-	-	-	-	-	-
NPEPGNMH_03694	2.05e-51	-	-	-	S	-	-	-	YolD-like protein
NPEPGNMH_03695	1.52e-79	dinB2	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NPEPGNMH_03696	6.17e-158	dinB2	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NPEPGNMH_03698	6.23e-267	-	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
NPEPGNMH_03702	1.36e-08	-	-	-	-	-	-	-	-
NPEPGNMH_03703	6.85e-229	-	-	-	-	-	-	-	-
NPEPGNMH_03704	1.92e-162	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
NPEPGNMH_03705	1.21e-90	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
NPEPGNMH_03707	3.92e-76	-	-	-	K	-	-	-	Helix-turn-helix
NPEPGNMH_03708	6.27e-51	-	-	-	S	-	-	-	TM2 domain
NPEPGNMH_03709	1.3e-157	xlnB	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
NPEPGNMH_03710	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
NPEPGNMH_03714	9.26e-218	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
NPEPGNMH_03715	3.88e-153	lin0465	-	-	S	-	-	-	DJ-1/PfpI family
NPEPGNMH_03716	6.84e-103	yoaW	-	-	-	-	-	-	-
NPEPGNMH_03717	1.11e-202	yoaV	-	-	EG	-	-	-	EamA-like transporter family
NPEPGNMH_03718	6.67e-203	yoaU	-	-	K	-	-	-	LysR substrate binding domain
NPEPGNMH_03719	6.92e-192	yoaT	-	-	S	-	-	-	Protein of unknown function (DUF817)
NPEPGNMH_03720	7.38e-50	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
NPEPGNMH_03721	1.6e-98	yoaS	-	-	S	-	-	-	Protein of unknown function (DUF2975)
NPEPGNMH_03722	3.63e-218	yoaR	-	-	V	-	-	-	vancomycin resistance protein
NPEPGNMH_03723	2.36e-116	-	-	-	-	-	-	-	-
NPEPGNMH_03725	7.38e-88	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
NPEPGNMH_03726	4.7e-188	yoaP	-	-	K	-	-	-	YoaP-like
NPEPGNMH_03728	1.95e-296	oxdD	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
NPEPGNMH_03730	5.08e-171	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
NPEPGNMH_03731	1.5e-254	-	4.2.2.10	-	G	ko:K01732	-	ko00000,ko01000	Amb_all
NPEPGNMH_03732	1.79e-145	yoaK	-	-	S	-	-	-	Membrane
NPEPGNMH_03733	2.61e-171	yoaJ	-	-	G	ko:K20628	-	ko00000	Endoglucanase C-terminal domain subunit and related proteins
NPEPGNMH_03734	0.0	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
NPEPGNMH_03735	0.0	yoaH	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
NPEPGNMH_03736	8.23e-62	-	-	-	S	-	-	-	Protein of unknown function (DUF4025)
NPEPGNMH_03737	1.25e-20	-	-	-	-	-	-	-	-
NPEPGNMH_03739	2.08e-44	yoaF	-	-	-	-	-	-	-
NPEPGNMH_03740	0.0	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NPEPGNMH_03741	3.41e-243	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPEPGNMH_03742	0.0	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
NPEPGNMH_03743	1.11e-300	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
NPEPGNMH_03744	5.91e-125	yoaA	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NPEPGNMH_03745	1.34e-185	yoxB	-	-	-	-	-	-	-
NPEPGNMH_03746	8.39e-57	yoxC	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
NPEPGNMH_03747	1.13e-79	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
NPEPGNMH_03748	2.74e-68	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
NPEPGNMH_03749	5.37e-79	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
NPEPGNMH_03750	2.72e-185	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NPEPGNMH_03751	8.13e-263	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NPEPGNMH_03752	2.61e-205	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
NPEPGNMH_03753	6.63e-69	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
NPEPGNMH_03754	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
NPEPGNMH_03755	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
NPEPGNMH_03756	7.23e-238	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NPEPGNMH_03757	1.3e-202	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
NPEPGNMH_03758	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
NPEPGNMH_03759	3.31e-47	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
NPEPGNMH_03760	1.14e-124	-	-	-	L	-	-	-	Integrase
NPEPGNMH_03762	7.14e-128	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
NPEPGNMH_03763	9.8e-313	yoeA	-	-	V	-	-	-	MATE efflux family protein
NPEPGNMH_03764	2.54e-245	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
NPEPGNMH_03765	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
NPEPGNMH_03766	0.0	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
NPEPGNMH_03768	3.47e-205	ybaS	-	-	S	-	-	-	Na -dependent transporter
NPEPGNMH_03769	4.01e-184	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
NPEPGNMH_03770	3.51e-228	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPEPGNMH_03771	2.88e-226	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPEPGNMH_03772	9.23e-219	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
NPEPGNMH_03773	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
NPEPGNMH_03774	3.6e-306	ybbC	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_03775	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
NPEPGNMH_03776	0.0	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
NPEPGNMH_03777	7.29e-304	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NPEPGNMH_03778	3.82e-194	ybbH	-	-	K	-	-	-	transcriptional
NPEPGNMH_03779	4.04e-211	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NPEPGNMH_03780	1.55e-114	ybbJ	-	-	J	-	-	-	acetyltransferase
NPEPGNMH_03781	4.19e-101	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
NPEPGNMH_03787	1.6e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NPEPGNMH_03788	2.73e-152	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
NPEPGNMH_03789	5.43e-189	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NPEPGNMH_03790	4.16e-292	ybbR	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_03791	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NPEPGNMH_03792	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NPEPGNMH_03793	3.67e-227	alkA	3.2.2.21	-	L	ko:K01247,ko:K13529	ko03410,map03410	ko00000,ko00001,ko01000,ko03000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NPEPGNMH_03794	2.25e-157	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
NPEPGNMH_03795	4.49e-130	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NPEPGNMH_03796	0.0	ndhF	1.6.5.3	-	CP	ko:K05577	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NPEPGNMH_03797	0.0	ybcC	-	-	S	ko:K09822	-	ko00000	Belongs to the UPF0753 family
NPEPGNMH_03798	2.51e-125	ybcF	-	-	P	-	-	-	carbonic anhydrase
NPEPGNMH_03799	5.59e-64	-	-	-	-	-	-	-	-
NPEPGNMH_03800	3.6e-80	ybcI	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
NPEPGNMH_03801	9.45e-67	-	-	-	K	-	-	-	Helix-turn-helix domain
NPEPGNMH_03802	1.14e-258	ybcL	-	-	EGP	ko:K08164	-	ko00000,ko02000	COG2814 Arabinose efflux permease
NPEPGNMH_03804	7.24e-304	-	-	-	J	-	-	-	4Fe-4S single cluster domain
NPEPGNMH_03805	3.37e-76	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
NPEPGNMH_03806	5.07e-233	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
NPEPGNMH_03807	8.07e-174	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NPEPGNMH_03808	3.99e-313	skfF	-	-	S	-	-	-	ABC transporter
NPEPGNMH_03809	3.88e-118	-	-	-	C	-	-	-	HEAT repeats
NPEPGNMH_03810	5.88e-103	-	-	-	CO	-	-	-	Thioredoxin-like domain
NPEPGNMH_03811	8.07e-233	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NPEPGNMH_03812	2.93e-159	-	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulatory protein, C terminal
NPEPGNMH_03813	4.12e-221	-	-	-	T	-	-	-	His Kinase A (phospho-acceptor) domain
NPEPGNMH_03815	2.49e-181	ybdM	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
NPEPGNMH_03816	6.61e-196	ybdN	-	-	-	-	-	-	-
NPEPGNMH_03817	1.19e-278	ybdO	-	-	S	-	-	-	Domain of unknown function (DUF4885)
NPEPGNMH_03818	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
NPEPGNMH_03819	5.46e-51	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
NPEPGNMH_03820	6.92e-41	ybxH	-	-	S	-	-	-	Family of unknown function (DUF5370)
NPEPGNMH_03821	3.86e-195	ybxI	3.5.2.6	-	V	ko:K17838	ko01501,map01501	ko00000,ko00001,ko01000	beta-lactamase
NPEPGNMH_03822	9.97e-317	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
NPEPGNMH_03823	1.11e-54	ybyB	-	-	-	-	-	-	-
NPEPGNMH_03824	0.0	ybeC	-	-	E	-	-	-	amino acid
NPEPGNMH_03825	7.3e-213	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
NPEPGNMH_03826	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
NPEPGNMH_03827	3.57e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
NPEPGNMH_03828	8.93e-220	ybfA	-	-	K	-	-	-	FR47-like protein
NPEPGNMH_03829	2.36e-287	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
NPEPGNMH_03832	0.0	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
NPEPGNMH_03833	5.27e-208	ybfH	-	-	EG	-	-	-	EamA-like transporter family
NPEPGNMH_03834	7.39e-188	ybfI	-	-	K	-	-	-	AraC-like ligand binding domain
NPEPGNMH_03835	5.85e-274	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NPEPGNMH_03836	5.04e-230	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
NPEPGNMH_03838	2.02e-216	-	-	-	S	-	-	-	Alpha/beta hydrolase family
NPEPGNMH_03839	6.9e-124	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NPEPGNMH_03840	7.07e-112	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
NPEPGNMH_03841	4.33e-190	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NPEPGNMH_03842	2.33e-61	ybfN	-	-	-	-	-	-	-
NPEPGNMH_03843	0.0	-	-	-	S	ko:K06880	-	ko00000,ko01000,ko01504	Erythromycin esterase
NPEPGNMH_03844	5.14e-214	ybfP	-	-	K	ko:K13653	-	ko00000,ko03000	Transcriptional regulator
NPEPGNMH_03845	1.16e-244	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
NPEPGNMH_03846	1.58e-228	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NPEPGNMH_03847	1.5e-31	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NPEPGNMH_03848	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NPEPGNMH_03849	7.72e-177	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NPEPGNMH_03850	2.91e-165	-	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
NPEPGNMH_03852	3.74e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
NPEPGNMH_03853	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
NPEPGNMH_03854	2.23e-234	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
NPEPGNMH_03855	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
NPEPGNMH_03856	9.16e-240	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
NPEPGNMH_03857	3.55e-294	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NPEPGNMH_03858	1.72e-217	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
NPEPGNMH_03859	4.1e-222	ycbC	4.2.1.41	-	EM	ko:K01707	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	5-dehydro-4-deoxyglucarate dehydratase activity
NPEPGNMH_03860	0.0	ycbD	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NPEPGNMH_03861	0.0	gudP	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
NPEPGNMH_03862	0.0	gudD	4.2.1.40	-	M	ko:K01706	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
NPEPGNMH_03863	2.3e-161	ycbG	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
NPEPGNMH_03864	0.0	garD	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
NPEPGNMH_03865	4.64e-227	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
NPEPGNMH_03866	8.73e-33	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
NPEPGNMH_03867	1.87e-220	eamA1	-	-	EG	-	-	-	spore germination
NPEPGNMH_03868	6.64e-162	ycbL	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPEPGNMH_03869	1.66e-218	ycbM	-	-	T	-	-	-	Histidine kinase
NPEPGNMH_03870	1.66e-216	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPGNMH_03871	4.25e-150	-	-	-	S	-	-	-	ABC-2 family transporter protein
NPEPGNMH_03872	2.21e-76	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
NPEPGNMH_03873	1.82e-102	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
NPEPGNMH_03874	4.66e-175	ycbR	-	-	T	-	-	-	vWA found in TerF C terminus
NPEPGNMH_03875	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
NPEPGNMH_03876	3.12e-38	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NPEPGNMH_03877	7.6e-160	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NPEPGNMH_03878	2.52e-156	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NPEPGNMH_03879	3.48e-268	ycbU	-	-	E	-	-	-	Selenocysteine lyase
NPEPGNMH_03880	2.87e-308	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
NPEPGNMH_03881	6.54e-132	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
NPEPGNMH_03882	8.74e-260	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NPEPGNMH_03883	4e-147	-	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NPEPGNMH_03884	4.32e-78	-	-	-	S	-	-	-	RDD family
NPEPGNMH_03885	2.49e-255	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
NPEPGNMH_03886	9.56e-217	natK	2.7.13.3	-	T	ko:K11640	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
NPEPGNMH_03887	6.86e-163	natR	-	-	T	ko:K02477,ko:K11641	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
NPEPGNMH_03888	5.41e-171	natA	3.6.3.7	-	CP	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NPEPGNMH_03889	9.75e-258	-	-	-	CP	ko:K09696	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
NPEPGNMH_03890	5.83e-223	yccK	-	-	C	-	-	-	Aldo keto reductase
NPEPGNMH_03891	1.35e-241	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
NPEPGNMH_03892	0.0	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NPEPGNMH_03893	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NPEPGNMH_03894	3.91e-125	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
NPEPGNMH_03895	1.42e-248	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
NPEPGNMH_03896	5.87e-181	-	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
NPEPGNMH_03897	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
NPEPGNMH_03898	1.95e-221	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
NPEPGNMH_03899	1.99e-170	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NPEPGNMH_03900	4.63e-173	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NPEPGNMH_03901	9.18e-242	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPEPGNMH_03902	2.64e-141	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
NPEPGNMH_03903	8.9e-137	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
NPEPGNMH_03904	4.97e-138	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
NPEPGNMH_03905	4.1e-176	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
NPEPGNMH_03906	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
NPEPGNMH_03907	2.96e-245	yceH	-	-	P	-	-	-	Belongs to the TelA family
NPEPGNMH_03908	2.32e-279	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
NPEPGNMH_03909	1.17e-267	-	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
NPEPGNMH_03910	4.82e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
NPEPGNMH_03911	8.99e-293	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
NPEPGNMH_03912	1.75e-150	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
NPEPGNMH_03913	2.01e-210	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
NPEPGNMH_03914	2.5e-279	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
NPEPGNMH_03915	0.0	ycgA	-	-	S	-	-	-	Membrane
NPEPGNMH_03916	1.25e-127	ycgB	-	-	-	-	-	-	-
NPEPGNMH_03917	0.0	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
NPEPGNMH_03918	2.06e-233	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NPEPGNMH_03919	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
NPEPGNMH_03920	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
NPEPGNMH_03921	3.7e-101	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NPEPGNMH_03922	6.42e-147	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
NPEPGNMH_03923	1.85e-195	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
NPEPGNMH_03924	0.0	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
NPEPGNMH_03925	7.6e-145	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
NPEPGNMH_03926	1.83e-191	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NPEPGNMH_03927	1.31e-140	tmrB	-	-	S	-	-	-	AAA domain
NPEPGNMH_03928	1.05e-136	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NPEPGNMH_03929	1.29e-186	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
NPEPGNMH_03930	2.05e-230	ycgK	-	-	K	ko:K04761	ko02026,map02026	ko00000,ko00001,ko03000	LysR substrate binding domain
NPEPGNMH_03931	1.15e-233	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
NPEPGNMH_03932	7.76e-187	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
NPEPGNMH_03933	3.63e-218	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
NPEPGNMH_03934	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
NPEPGNMH_03935	1.15e-207	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NPEPGNMH_03936	1.71e-96	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NPEPGNMH_03937	3.92e-288	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
NPEPGNMH_03938	3.82e-195	ycgQ	-	-	S	ko:K08986	-	ko00000	membrane
NPEPGNMH_03939	3.19e-187	ycgR	-	-	S	ko:K07089	-	ko00000	permeases
NPEPGNMH_03940	4.74e-209	ycgS	-	-	I	-	-	-	alpha/beta hydrolase fold
NPEPGNMH_03941	8.9e-247	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
NPEPGNMH_03942	6.59e-117	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
NPEPGNMH_03943	7.02e-228	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
NPEPGNMH_03944	1.2e-74	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
NPEPGNMH_03945	4.5e-310	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NPEPGNMH_03946	2.65e-245	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NPEPGNMH_03947	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NPEPGNMH_03948	0.0	nasB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Assimilatory nitrate reductase (electron transfer subunit)
NPEPGNMH_03949	5.51e-283	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
NPEPGNMH_03950	1.05e-222	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Converts GTP to 7,8-dihydroneopterin triphosphate
NPEPGNMH_03951	2.56e-141	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
NPEPGNMH_03952	6.78e-291	yciC	-	-	S	-	-	-	GTPases (G3E family)
NPEPGNMH_03953	2.99e-149	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
NPEPGNMH_03954	3.76e-187	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
NPEPGNMH_03957	5.95e-101	yckC	-	-	S	-	-	-	membrane
NPEPGNMH_03958	3.53e-69	yckD	-	-	S	-	-	-	Protein of unknown function (DUF2680)
NPEPGNMH_03959	0.0	yckE	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NPEPGNMH_03960	9.4e-48	nin	-	-	S	-	-	-	Competence protein J (ComJ)
NPEPGNMH_03961	4.78e-101	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
NPEPGNMH_03962	6.52e-269	tlpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
NPEPGNMH_03963	1.38e-127	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
NPEPGNMH_03964	2.39e-138	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
NPEPGNMH_03965	6.05e-86	hxlR	-	-	K	-	-	-	transcriptional
NPEPGNMH_03966	3.42e-286	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPEPGNMH_03967	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
NPEPGNMH_03968	1.63e-179	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
NPEPGNMH_03969	1.38e-291	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NPEPGNMH_03970	1.61e-126	-	-	-	S	-	-	-	YcxB-like protein
NPEPGNMH_03971	1.77e-209	ycxC	-	-	EG	-	-	-	EamA-like transporter family
NPEPGNMH_03972	0.0	ycxD	-	-	K	-	-	-	GntR family transcriptional regulator
NPEPGNMH_03973	1.37e-144	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
NPEPGNMH_03974	3.04e-148	yczE	-	-	S	ko:K07149	-	ko00000	membrane
NPEPGNMH_03975	7.11e-172	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
NPEPGNMH_03976	4.6e-157	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
NPEPGNMH_03977	1.5e-188	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
NPEPGNMH_03978	9.2e-210	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
NPEPGNMH_03979	2.33e-142	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NPEPGNMH_03980	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
NPEPGNMH_03981	9.86e-53	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
NPEPGNMH_03982	3.05e-109	yclD	-	-	-	-	-	-	-
NPEPGNMH_03983	5.12e-207	yclE	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Alpha beta hydrolase
NPEPGNMH_03984	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
NPEPGNMH_03985	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
NPEPGNMH_03987	0.0	gerKA	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
NPEPGNMH_03988	8.35e-297	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
NPEPGNMH_03989	2.29e-254	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
NPEPGNMH_03990	2.05e-156	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NPEPGNMH_03991	5.59e-280	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
NPEPGNMH_03992	2.23e-165	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPEPGNMH_03993	0.0	yclK	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NPEPGNMH_03994	7.71e-98	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
NPEPGNMH_03996	1.58e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
NPEPGNMH_03997	6.5e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
NPEPGNMH_03998	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
NPEPGNMH_03999	5.42e-206	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPEPGNMH_04000	4.69e-211	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPEPGNMH_04001	5.63e-176	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NPEPGNMH_04002	4.98e-223	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
NPEPGNMH_04003	0.0	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
NPEPGNMH_04004	1.76e-199	ycnC	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_04005	2.12e-174	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Oxidoreductase
NPEPGNMH_04006	1.68e-60	ycnE	-	-	S	-	-	-	Monooxygenase
NPEPGNMH_04007	6.51e-69	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
NPEPGNMH_04008	2.77e-70	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NPEPGNMH_04009	5.84e-264	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NPEPGNMH_04010	2.4e-313	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NPEPGNMH_04011	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NPEPGNMH_04012	1.67e-190	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
NPEPGNMH_04013	5.9e-187	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPEPGNMH_04014	1.07e-138	ycnI	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_04015	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
NPEPGNMH_04016	5.18e-139	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
NPEPGNMH_04017	1.34e-74	-	-	-	-	-	-	-	-
NPEPGNMH_04018	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
NPEPGNMH_04019	8.3e-95	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
NPEPGNMH_04020	9.41e-22	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
NPEPGNMH_04021	2.16e-211	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
NPEPGNMH_04022	1.01e-256	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
NPEPGNMH_04024	6.21e-97	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NPEPGNMH_04025	2.64e-147	-	-	-	Q	-	-	-	COG0412 Dienelactone hydrolase and related enzymes
NPEPGNMH_04026	2.29e-88	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
NPEPGNMH_04028	1.9e-177	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
NPEPGNMH_04029	9.39e-182	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
NPEPGNMH_04030	2.78e-273	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
NPEPGNMH_04031	7e-190	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
NPEPGNMH_04032	5.04e-173	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
NPEPGNMH_04033	1.99e-238	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
NPEPGNMH_04034	3.8e-171	kipR	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_04035	4.18e-154	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
NPEPGNMH_04037	7.67e-66	yczJ	-	-	S	-	-	-	biosynthesis
NPEPGNMH_04038	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
NPEPGNMH_04039	3.26e-224	ycsN	-	-	S	-	-	-	Oxidoreductase
NPEPGNMH_04040	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
NPEPGNMH_04041	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
NPEPGNMH_04042	6.05e-129	ydaC	-	-	Q	-	-	-	Methyltransferase domain
NPEPGNMH_04043	3.74e-207	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPEPGNMH_04044	2.36e-126	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
NPEPGNMH_04045	6.6e-134	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NPEPGNMH_04046	5.24e-101	ydaG	-	-	S	-	-	-	general stress protein
NPEPGNMH_04047	1.31e-178	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NPEPGNMH_04048	1.88e-62	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
NPEPGNMH_04049	3.95e-98	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
NPEPGNMH_04050	2.68e-48	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NPEPGNMH_04051	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NPEPGNMH_04052	3.08e-267	ydaJ	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
NPEPGNMH_04053	1.14e-195	ydaK	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
NPEPGNMH_04054	0.0	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
NPEPGNMH_04055	1.93e-304	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
NPEPGNMH_04056	4.03e-196	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
NPEPGNMH_04057	3.76e-212	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
NPEPGNMH_04058	0.0	ydaO	-	-	E	-	-	-	amino acid
NPEPGNMH_04059	3.75e-103	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
NPEPGNMH_04060	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
NPEPGNMH_04061	2.14e-53	-	-	-	-	-	-	-	-
NPEPGNMH_04062	3.9e-286	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
NPEPGNMH_04063	1.67e-42	ydaS	-	-	S	-	-	-	membrane
NPEPGNMH_04064	2.25e-100	ydaT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
NPEPGNMH_04065	1.06e-190	ydbA	-	-	P	-	-	-	EcsC protein family
NPEPGNMH_04066	8.37e-11	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
NPEPGNMH_04067	7.58e-79	ydbB	-	-	G	-	-	-	Cupin domain
NPEPGNMH_04068	5.41e-84	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
NPEPGNMH_04069	1.35e-198	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
NPEPGNMH_04070	3.66e-253	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NPEPGNMH_04071	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
NPEPGNMH_04072	3.39e-155	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
NPEPGNMH_04073	4.43e-290	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NPEPGNMH_04074	3.25e-231	ydbI	-	-	S	-	-	-	AI-2E family transporter
NPEPGNMH_04075	2.28e-219	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPGNMH_04076	7.34e-160	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NPEPGNMH_04077	9.32e-70	ydbL	-	-	-	-	-	-	-
NPEPGNMH_04078	1.83e-280	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
NPEPGNMH_04079	1.49e-26	-	-	-	S	-	-	-	Fur-regulated basic protein B
NPEPGNMH_04081	1.91e-202	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NPEPGNMH_04082	4.19e-75	ydbP	-	-	CO	-	-	-	Thioredoxin
NPEPGNMH_04083	3.07e-258	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
NPEPGNMH_04084	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NPEPGNMH_04085	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NPEPGNMH_04086	2.12e-107	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
NPEPGNMH_04087	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
NPEPGNMH_04088	2.53e-139	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
NPEPGNMH_04089	1.95e-78	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NPEPGNMH_04090	4.66e-234	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
NPEPGNMH_04091	5.29e-284	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NPEPGNMH_04092	9.49e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
NPEPGNMH_04093	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
NPEPGNMH_04094	8.58e-184	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
NPEPGNMH_04095	1.8e-74	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
NPEPGNMH_04096	8.56e-90	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
NPEPGNMH_04097	1.31e-243	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
NPEPGNMH_04098	1.97e-70	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
NPEPGNMH_04099	2.48e-111	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
NPEPGNMH_04100	1.55e-178	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPEPGNMH_04101	1.86e-141	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
NPEPGNMH_04105	1.32e-106	ydcG	-	-	S	-	-	-	EVE domain
NPEPGNMH_04106	1.59e-40	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NPEPGNMH_04107	1.08e-43	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NPEPGNMH_04108	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
NPEPGNMH_04109	1.93e-110	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
NPEPGNMH_04117	4.41e-270	ydcL	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NPEPGNMH_04118	1.41e-119	-	-	-	E	-	-	-	IrrE N-terminal-like domain
NPEPGNMH_04119	1.91e-81	-	-	-	K	-	-	-	Transcriptional
NPEPGNMH_04120	8.96e-24	-	-	-	-	-	-	-	-
NPEPGNMH_04121	9.52e-56	-	-	-	-	-	-	-	-
NPEPGNMH_04123	1.84e-83	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF961)
NPEPGNMH_04124	0.0	ydcQ	-	-	D	ko:K03466	-	ko00000,ko03036	Ftsk spoiiie family protein
NPEPGNMH_04125	2.62e-263	nicK	-	-	L	ko:K07467	-	ko00000	Replication initiation factor
NPEPGNMH_04128	1.38e-43	yddA	-	-	-	-	-	-	-
NPEPGNMH_04129	7.65e-232	yddB	-	-	S	-	-	-	Conjugative transposon protein TcpC
NPEPGNMH_04130	3.41e-54	yddC	-	-	-	-	-	-	-
NPEPGNMH_04131	2.82e-50	yddD	-	-	S	-	-	-	TcpE family
NPEPGNMH_04132	0.0	yddE	-	-	S	-	-	-	AAA-like domain
NPEPGNMH_04133	2.81e-74	-	-	-	S	-	-	-	Domain of unknown function (DUF1874)
NPEPGNMH_04134	0.0	yddG	-	-	S	-	-	-	maturation of SSU-rRNA
NPEPGNMH_04135	4.74e-243	yddH	-	-	M	-	-	-	Lysozyme-like
NPEPGNMH_04136	4.05e-114	yddI	-	-	-	-	-	-	-
NPEPGNMH_04137	6.67e-86	yddJ	-	-	S	-	-	-	Domain of unknown function with cystatin-like fold (DUF4467)
NPEPGNMH_04138	8.08e-192	-	-	-	S	-	-	-	TIR domain
NPEPGNMH_04139	2.55e-38	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
NPEPGNMH_04140	2.19e-53	-	-	-	S	ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
NPEPGNMH_04142	2.93e-212	-	-	-	-	-	-	-	-
NPEPGNMH_04143	2.43e-241	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPEPGNMH_04144	2.23e-54	lrpA	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	transcriptional
NPEPGNMH_04145	2.17e-102	lrpB	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	transcriptional
NPEPGNMH_04146	1.62e-128	yddQ	-	-	Q	-	-	-	Isochorismatase family
NPEPGNMH_04147	1.34e-184	yddR	-	-	S	-	-	-	Zn-dependent hydrolases of the beta-lactamase fold
NPEPGNMH_04148	3.35e-288	ydeG3	-	-	EGP	-	-	-	Major Facilitator Superfamily
NPEPGNMH_04153	7.94e-22	ydhU	-	-	P	ko:K07217	-	ko00000	Manganese containing catalase
NPEPGNMH_04154	1.12e-98	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
NPEPGNMH_04155	3.49e-273	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
NPEPGNMH_04156	1.93e-244	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
NPEPGNMH_04157	9.28e-219	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
NPEPGNMH_04158	1.9e-171	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
NPEPGNMH_04159	0.0	ydhP	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NPEPGNMH_04160	2.27e-305	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPEPGNMH_04161	6.09e-70	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NPEPGNMH_04162	7.97e-65	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NPEPGNMH_04163	6.3e-255	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
NPEPGNMH_04164	4.01e-130	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
NPEPGNMH_04165	1.25e-236	ydhJ	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NPEPGNMH_04166	1.43e-112	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NPEPGNMH_04168	9.93e-91	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
NPEPGNMH_04169	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
NPEPGNMH_04170	8.36e-129	-	-	-	-	-	-	-	-
NPEPGNMH_04171	9.61e-290	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NPEPGNMH_04172	8.92e-310	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
NPEPGNMH_04173	5.24e-158	ydhC	-	-	K	-	-	-	FCD
NPEPGNMH_04174	1.77e-155	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NPEPGNMH_04175	5.97e-267	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
NPEPGNMH_04176	1.15e-90	-	-	-	K	-	-	-	Winged helix DNA-binding domain
NPEPGNMH_04177	3.16e-108	ydgI	-	-	C	-	-	-	nitroreductase
NPEPGNMH_04178	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
NPEPGNMH_04179	2.06e-104	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NPEPGNMH_04180	5.09e-119	-	-	-	S	-	-	-	DinB family
NPEPGNMH_04181	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
NPEPGNMH_04182	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
NPEPGNMH_04183	2.49e-114	yycN	-	-	K	-	-	-	Acetyltransferase
NPEPGNMH_04184	4.21e-72	-	-	-	S	-	-	-	DoxX-like family
NPEPGNMH_04185	7.86e-132	ydgC	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NPEPGNMH_04186	2.19e-56	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
NPEPGNMH_04187	2.74e-50	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
NPEPGNMH_04188	3.13e-99	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
NPEPGNMH_04189	4.44e-160	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
NPEPGNMH_04190	2.52e-145	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
NPEPGNMH_04192	5.33e-39	-	-	-	-	-	-	-	-
NPEPGNMH_04193	2.4e-21	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
NPEPGNMH_04194	9.63e-77	ydfQ	-	-	CO	-	-	-	Thioredoxin
NPEPGNMH_04195	8.02e-84	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
NPEPGNMH_04196	9.49e-239	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
NPEPGNMH_04197	3.45e-145	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
NPEPGNMH_04198	3.15e-200	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NPEPGNMH_04199	1.21e-137	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
NPEPGNMH_04200	2.59e-18	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
NPEPGNMH_04201	6.79e-152	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
NPEPGNMH_04202	9.73e-226	-	-	-	S	-	-	-	Alpha/beta hydrolase family
NPEPGNMH_04203	0.0	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
NPEPGNMH_04204	2.3e-142	ydfI	-	-	K	ko:K11624	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPEPGNMH_04205	4.11e-253	ydfH	2.7.13.3	-	T	ko:K11623	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NPEPGNMH_04207	1.37e-104	-	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NPEPGNMH_04208	5.24e-159	ydfF	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
NPEPGNMH_04209	5.97e-151	ydfE	-	-	S	-	-	-	Flavin reductase like domain
NPEPGNMH_04210	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NPEPGNMH_04211	3.05e-207	-	-	-	EG	-	-	-	EamA-like transporter family
NPEPGNMH_04212	2.61e-181	-	-	-	J	-	-	-	GNAT acetyltransferase
NPEPGNMH_04213	9.07e-297	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NPEPGNMH_04214	2.56e-76	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
NPEPGNMH_04215	3.74e-136	ydeS	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_04216	1.51e-261	ydeR	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
NPEPGNMH_04217	2.44e-142	ywrO	-	-	S	ko:K11748	-	ko00000,ko02000	NADPH-quinone reductase (modulator of drug activity B)
NPEPGNMH_04218	5.03e-91	ydeP	-	-	K	-	-	-	Transcriptional regulator
NPEPGNMH_04219	1.68e-196	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
NPEPGNMH_04220	1.33e-77	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
NPEPGNMH_04221	8.6e-138	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
NPEPGNMH_04222	3.68e-97	ydeM1	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
NPEPGNMH_04223	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NPEPGNMH_04224	4.66e-197	ydeK	-	-	EG	-	-	-	-transporter
NPEPGNMH_04225	6.11e-150	-	-	-	-	-	-	-	-
NPEPGNMH_04226	1.26e-138	ydeI	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
NPEPGNMH_04227	4.76e-72	ydeH	-	-	-	-	-	-	-
NPEPGNMH_04228	1.19e-280	ydeG	-	-	EGP	-	-	-	Major facilitator superfamily
NPEPGNMH_04229	0.0	-	-	-	K	-	-	-	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NPEPGNMH_04230	2.87e-213	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
NPEPGNMH_04231	4.99e-224	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NPEPGNMH_04232	3.23e-215	-	-	-	K	-	-	-	AraC-like ligand binding domain
NPEPGNMH_04233	2.47e-47	ydzE	-	-	EG	-	-	-	spore germination
NPEPGNMH_04234	4.05e-82	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
NPEPGNMH_04235	4.22e-41	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
NPEPGNMH_04236	4.24e-146	ydeA	-	-	S	-	-	-	DJ-1/PfpI family
NPEPGNMH_04238	8.72e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
NPEPGNMH_04239	2.76e-65	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
NPEPGNMH_04240	7.74e-257	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
NPEPGNMH_04241	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
NPEPGNMH_04242	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NPEPGNMH_04243	3.8e-251	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NPEPGNMH_04244	2.57e-252	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
NPEPGNMH_04245	1.82e-162	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NPEPGNMH_04246	6.35e-113	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NPEPGNMH_04247	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NPEPGNMH_04248	1.91e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
NPEPGNMH_04249	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NPEPGNMH_04250	1.13e-37	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NPEPGNMH_04251	4.29e-174	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NPEPGNMH_04252	3.31e-114	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
NPEPGNMH_04253	3.27e-149	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
NPEPGNMH_04254	2.65e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NPEPGNMH_04255	1.37e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
NPEPGNMH_04256	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NPEPGNMH_04257	1.82e-162	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NPEPGNMH_04258	4.03e-104	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NPEPGNMH_04259	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NPEPGNMH_04260	5.1e-140	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
NPEPGNMH_04261	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPEPGNMH_04262	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPEPGNMH_04263	1.99e-44	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
NPEPGNMH_04264	6.67e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NPEPGNMH_04265	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NPEPGNMH_04266	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NPEPGNMH_04267	2.01e-287	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NPEPGNMH_04268	8.78e-238	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
NPEPGNMH_04269	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
NPEPGNMH_04270	7.2e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NPEPGNMH_04271	7.43e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
NPEPGNMH_04272	9.04e-30	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NPEPGNMH_04273	2.72e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NPEPGNMH_04274	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NPEPGNMH_04275	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NPEPGNMH_04276	5.9e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NPEPGNMH_04277	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NPEPGNMH_04278	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
NPEPGNMH_04279	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NPEPGNMH_04280	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NPEPGNMH_04281	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NPEPGNMH_04282	7.72e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NPEPGNMH_04283	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NPEPGNMH_04284	3.11e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NPEPGNMH_04285	4.47e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NPEPGNMH_04286	2.89e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NPEPGNMH_04287	9.16e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NPEPGNMH_04288	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
NPEPGNMH_04289	7.32e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
NPEPGNMH_04290	5.7e-298	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NPEPGNMH_04291	6.17e-158	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NPEPGNMH_04292	2.32e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
NPEPGNMH_04293	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NPEPGNMH_04294	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
NPEPGNMH_04295	1.09e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NPEPGNMH_04296	3.24e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NPEPGNMH_04297	7.01e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPEPGNMH_04298	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
NPEPGNMH_04299	7.5e-200	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPEPGNMH_04300	2.69e-197	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPEPGNMH_04301	1.6e-177	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPEPGNMH_04302	1.51e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NPEPGNMH_04303	1.13e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NPEPGNMH_04304	4.28e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
NPEPGNMH_04305	2.14e-186	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
NPEPGNMH_04306	2.54e-91	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
NPEPGNMH_04307	2.22e-170	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
NPEPGNMH_04308	1.1e-255	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NPEPGNMH_04309	1.04e-122	gerD	-	-	-	ko:K06294	-	ko00000	-
NPEPGNMH_04310	1.1e-132	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
NPEPGNMH_04311	4.31e-181	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
NPEPGNMH_04312	2.21e-42	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
NPEPGNMH_04313	5.76e-98	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
NPEPGNMH_04314	5.05e-260	yaaN	-	-	P	-	-	-	Belongs to the TelA family
NPEPGNMH_04315	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
NPEPGNMH_04316	2.82e-147	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NPEPGNMH_04317	1.02e-72	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_04318	1.26e-95	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
NPEPGNMH_04319	2.42e-236	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NPEPGNMH_04320	1.1e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
NPEPGNMH_04321	1.53e-56	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
NPEPGNMH_04322	4.36e-152	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
NPEPGNMH_04323	4.19e-65	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
NPEPGNMH_04324	7.26e-208	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NPEPGNMH_04325	1.51e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
NPEPGNMH_04326	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NPEPGNMH_04327	5.05e-185	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
NPEPGNMH_04328	1.91e-283	yabE	-	-	T	-	-	-	protein conserved in bacteria
NPEPGNMH_04329	1.05e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NPEPGNMH_04330	1.24e-199	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NPEPGNMH_04331	6.69e-200	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
NPEPGNMH_04332	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
NPEPGNMH_04333	3.96e-37	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
NPEPGNMH_04334	2.34e-207	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NPEPGNMH_04335	4.66e-196	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
NPEPGNMH_04336	3.45e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
NPEPGNMH_04337	2.45e-63	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
NPEPGNMH_04338	9e-310	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NPEPGNMH_04339	1.22e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NPEPGNMH_04340	1.45e-136	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NPEPGNMH_04341	2.03e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NPEPGNMH_04342	6.36e-54	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
NPEPGNMH_04343	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NPEPGNMH_04344	5.88e-121	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
NPEPGNMH_04345	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NPEPGNMH_04346	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
NPEPGNMH_04347	4.22e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NPEPGNMH_04348	1.91e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
NPEPGNMH_04349	2.21e-139	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
NPEPGNMH_04350	4.18e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
NPEPGNMH_04351	2.49e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
NPEPGNMH_04354	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
NPEPGNMH_04355	5.61e-168	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
NPEPGNMH_04356	1.25e-238	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
NPEPGNMH_04357	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NPEPGNMH_04358	4.82e-121	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
NPEPGNMH_04359	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NPEPGNMH_04360	6.92e-189	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NPEPGNMH_04361	9.54e-208	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NPEPGNMH_04362	5.08e-206	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
NPEPGNMH_04363	3.77e-218	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
NPEPGNMH_04364	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NPEPGNMH_04365	1.03e-137	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
NPEPGNMH_04366	2.27e-216	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
NPEPGNMH_04367	3.32e-205	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NPEPGNMH_04368	2.78e-82	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NPEPGNMH_04369	4.56e-115	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NPEPGNMH_04370	1.81e-41	yazB	-	-	K	-	-	-	transcriptional
NPEPGNMH_04371	7.88e-244	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NPEPGNMH_04372	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
NPEPGNMH_04373	4.5e-234	yaaC	-	-	S	-	-	-	YaaC-like Protein
NPEPGNMH_04374	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NPEPGNMH_04375	2.81e-316	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NPEPGNMH_04376	3.7e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NPEPGNMH_04377	1.66e-138	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NPEPGNMH_04378	9.79e-296	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NPEPGNMH_04380	3.72e-159	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
NPEPGNMH_04381	2.43e-150	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
NPEPGNMH_04382	7.7e-278	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
NPEPGNMH_04383	1.44e-127	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
NPEPGNMH_04384	1.55e-110	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NPEPGNMH_04385	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NPEPGNMH_04386	8.75e-55	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NPEPGNMH_04387	6.25e-124	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NPEPGNMH_04388	1.55e-42	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
NPEPGNMH_04389	5.3e-49	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
NPEPGNMH_04390	9.23e-150	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPEPGNMH_04391	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPEPGNMH_04392	0.0	-	-	-	Q	ko:K15665	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPEPGNMH_04393	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPEPGNMH_04394	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPEPGNMH_04395	2.29e-307	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPEPGNMH_04396	4.25e-36	-	-	-	D	-	-	-	Phage tail tape measure protein
NPEPGNMH_04397	2.53e-25	-	-	-	L	-	-	-	Transglycosylase SLT domain
NPEPGNMH_04398	4.73e-18	-	-	-	D	-	-	-	tape measure
NPEPGNMH_04399	5.49e-152	-	-	-	S	-	-	-	Phage tail protein
NPEPGNMH_04400	2.27e-152	-	-	-	S	-	-	-	peptidoglycan catabolic process
NPEPGNMH_04402	1.54e-15	virB5	-	-	U	ko:K03200,ko:K20266	ko02024,ko03070,map02024,map03070	ko00000,ko00001,ko00002,ko02044	conjugation
NPEPGNMH_04403	9.35e-25	-	-	-	L	-	-	-	Phage integrase family
NPEPGNMH_04409	1.23e-52	-	-	-	S	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphoribosyl-ATP pyrophosphohydrolase
NPEPGNMH_04410	3.23e-16	-	-	-	-	-	-	-	-
NPEPGNMH_04412	1.13e-23	-	-	-	S	-	-	-	3D domain
NPEPGNMH_04414	8.19e-31	-	6.5.1.1, 6.5.1.6, 6.5.1.7	-	L	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase OB-like domain
NPEPGNMH_04416	7.45e-64	-	-	-	L	-	-	-	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NPEPGNMH_04417	3.56e-64	-	-	-	L	-	-	-	Domain of unknown function (DUF1738)
NPEPGNMH_04421	3.14e-69	-	-	-	D	-	-	-	Phage tail tape measure protein
NPEPGNMH_04434	7.34e-25	-	-	-	M	-	-	-	Phage tail tape measure protein, TP901 family
NPEPGNMH_04436	1.08e-35	-	-	-	S	-	-	-	Phage tail tube protein
NPEPGNMH_04437	2.27e-63	-	-	-	S	-	-	-	Immunity protein 70
NPEPGNMH_04438	2.42e-123	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
NPEPGNMH_04439	1.95e-34	-	-	-	S	-	-	-	AAA domain
NPEPGNMH_04440	1.58e-164	-	-	-	-	-	-	-	-
NPEPGNMH_04443	1.57e-17	-	-	-	F	-	-	-	Guanylate kinase homologues.
NPEPGNMH_04445	1.5e-145	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
NPEPGNMH_04446	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
NPEPGNMH_04448	4.59e-38	-	-	-	S	-	-	-	DNA gyrase B subunit, carboxyl terminus
NPEPGNMH_04449	3.47e-68	-	-	-	S	-	-	-	Phage portal protein
NPEPGNMH_04450	2.89e-74	-	-	-	S	-	-	-	Ribonucleotide reductase, small chain
NPEPGNMH_04467	4.61e-60	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NPEPGNMH_04468	5.76e-49	-	-	-	S	-	-	-	Bacterial DNA polymerase III alpha subunit
NPEPGNMH_04469	2.21e-29	-	-	-	-	-	-	-	-
NPEPGNMH_04470	1.12e-14	-	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
NPEPGNMH_04472	2.15e-51	-	-	-	S	-	-	-	Phage capsid family
NPEPGNMH_04476	5e-17	-	-	-	S	-	-	-	DNA gyrase B subunit, carboxyl terminus
NPEPGNMH_04479	1.49e-62	-	-	-	-	-	-	-	-
NPEPGNMH_04480	7.2e-32	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
NPEPGNMH_04481	2.27e-22	-	-	-	L	-	-	-	Phage minor structural protein
NPEPGNMH_04482	5.95e-87	-	-	-	S	-	-	-	Phage integrase family
NPEPGNMH_04484	3.22e-10	-	-	-	S	-	-	-	DNA primase activity