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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MIEGLDIO_00001	9.65e-313	-	-	-	S	-	-	-	zinc finger
MIEGLDIO_00002	8.64e-97	-	-	-	S	-	-	-	Bacterial PH domain
MIEGLDIO_00003	2.94e-99	-	-	-	-	-	-	-	-
MIEGLDIO_00004	1.03e-255	-	-	-	V	-	-	-	Domain of unknown function (DUF3427)
MIEGLDIO_00005	0.0	-	3.6.4.12	-	L	ko:K03658	-	ko00000,ko01000,ko03400	Psort location Cytoplasmic, score 8.87
MIEGLDIO_00006	3.97e-234	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MIEGLDIO_00007	1.1e-91	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
MIEGLDIO_00008	2.12e-296	aspB	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
MIEGLDIO_00009	1.11e-214	ppx1	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
MIEGLDIO_00010	6.97e-129	tmp1	-	-	S	-	-	-	Domain of unknown function (DUF4391)
MIEGLDIO_00011	2.04e-253	-	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
MIEGLDIO_00013	8.4e-56	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MIEGLDIO_00014	1.05e-311	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MIEGLDIO_00015	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
MIEGLDIO_00016	3.18e-179	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MIEGLDIO_00017	1.02e-199	-	-	-	I	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
MIEGLDIO_00018	0.0	hgdC	-	-	I	-	-	-	CoA enzyme activase uncharacterised domain (DUF2229)
MIEGLDIO_00019	0.0	egtA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Glutamate-cysteine ligase family 2(GCS2)
MIEGLDIO_00020	5.5e-148	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MIEGLDIO_00021	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Beta-galactosidase trimerisation domain
MIEGLDIO_00022	1.99e-145	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MIEGLDIO_00023	5.39e-308	-	-	-	G	-	-	-	Transporter major facilitator family protein
MIEGLDIO_00024	0.0	-	3.2.1.45	GH30	G	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 TIM-barrel domain
MIEGLDIO_00025	4.55e-124	-	-	-	K	-	-	-	transcriptional regulator
MIEGLDIO_00026	6.41e-286	-	-	-	G	-	-	-	MFS/sugar transport protein
MIEGLDIO_00027	0.0	-	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
MIEGLDIO_00028	0.0	-	3.2.1.4, 3.2.1.58	GH5,GH9	G	ko:K01179,ko:K01210	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 5 (cellulase A) family
MIEGLDIO_00029	0.0	-	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 43
MIEGLDIO_00030	1.73e-307	-	3.2.1.4, 3.2.1.58	GH5,GH9	G	ko:K01179,ko:K01210	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 5 (cellulase A) family
MIEGLDIO_00031	1.1e-139	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MIEGLDIO_00032	0.0	bgl2	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
MIEGLDIO_00033	8.09e-279	-	-	-	U	ko:K08168,ko:K18926	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
MIEGLDIO_00034	3.41e-22	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MIEGLDIO_00035	4.38e-147	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein domain
MIEGLDIO_00036	4.89e-273	-	-	-	U	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
MIEGLDIO_00037	0.0	-	3.2.1.40	-	E	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase C-terminal domain
MIEGLDIO_00038	5.72e-230	-	-	-	G	-	-	-	Transporter major facilitator family protein
MIEGLDIO_00039	1.99e-264	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
MIEGLDIO_00040	8.86e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MIEGLDIO_00041	0.0	bglB	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
MIEGLDIO_00042	1.65e-134	-	-	-	K	-	-	-	MarR family
MIEGLDIO_00043	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MIEGLDIO_00044	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
MIEGLDIO_00045	1.7e-235	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
MIEGLDIO_00046	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
MIEGLDIO_00047	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MIEGLDIO_00048	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MIEGLDIO_00049	7.57e-211	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MIEGLDIO_00050	3.14e-25	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MIEGLDIO_00051	1.09e-148	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
MIEGLDIO_00052	1.01e-54	-	-	-	L	-	-	-	transposase activity
MIEGLDIO_00053	6.03e-162	-	-	-	L	-	-	-	PFAM Integrase catalytic
MIEGLDIO_00054	3.41e-41	-	-	-	-	-	-	-	-
MIEGLDIO_00057	1.87e-156	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
MIEGLDIO_00058	1.57e-305	-	4.4.1.8	-	E	ko:K00842,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
MIEGLDIO_00059	1.52e-239	-	-	-	K	-	-	-	LysR substrate binding domain protein
MIEGLDIO_00060	9.13e-198	-	-	-	S	-	-	-	Patatin-like phospholipase
MIEGLDIO_00061	1.95e-226	iaaA	3.4.19.5	-	E	ko:K13051	-	ko00000,ko01000,ko01002	Asparaginase
MIEGLDIO_00062	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
MIEGLDIO_00063	1.82e-30	-	-	-	S	ko:K07001	-	ko00000	lipid catabolic process
MIEGLDIO_00064	1.07e-186	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MIEGLDIO_00065	1.04e-215	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
MIEGLDIO_00066	6.1e-151	-	-	-	S	-	-	-	Vitamin K epoxide reductase
MIEGLDIO_00067	1.37e-220	PPA1328	3.1.3.97, 3.1.4.57	-	S	ko:K07053,ko:K20859	ko00440,map00440	ko00000,ko00001,ko01000	DNA polymerase alpha chain like domain
MIEGLDIO_00068	4.61e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF3107)
MIEGLDIO_00069	0.0	mphA	-	-	S	-	-	-	Aminoglycoside phosphotransferase
MIEGLDIO_00070	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MIEGLDIO_00071	0.0	-	-	-	S	-	-	-	Zincin-like metallopeptidase
MIEGLDIO_00072	9.98e-197	sdrC	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MIEGLDIO_00073	3.68e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3052)
MIEGLDIO_00075	0.0	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
MIEGLDIO_00076	1.19e-277	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MIEGLDIO_00077	5.54e-286	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MIEGLDIO_00078	0.0	-	-	-	I	-	-	-	acetylesterase activity
MIEGLDIO_00079	4.14e-173	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MIEGLDIO_00080	8.46e-197	uppS	2.5.1.31, 2.5.1.86, 2.5.1.88	-	H	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MIEGLDIO_00081	1.62e-294	-	-	-	F	-	-	-	nucleoside hydrolase
MIEGLDIO_00082	3.79e-238	-	-	-	P	-	-	-	NMT1/THI5 like
MIEGLDIO_00083	1.43e-189	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_00084	0.0	fosC	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
MIEGLDIO_00085	1.54e-307	lacY	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
MIEGLDIO_00086	7.57e-246	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MIEGLDIO_00087	3.37e-79	-	-	-	S	-	-	-	Thiamine-binding protein
MIEGLDIO_00088	4.31e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MIEGLDIO_00089	1.92e-171	thiE	2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17	-	H	ko:K03147,ko:K14153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MIEGLDIO_00090	4.66e-198	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MIEGLDIO_00091	0.0	-	-	-	-	-	-	-	-
MIEGLDIO_00092	0.0	pilT	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
MIEGLDIO_00093	0.0	pilB	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
MIEGLDIO_00094	1.38e-174	-	-	-	NU	ko:K02671	-	ko00000,ko02035,ko02044	Prokaryotic N-terminal methylation motif
MIEGLDIO_00095	1.04e-133	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
MIEGLDIO_00096	1.75e-58	-	-	-	NU	ko:K02650	ko02020,map02020	ko00000,ko00001,ko02035,ko02044	Prokaryotic N-terminal methylation motif
MIEGLDIO_00097	9.6e-293	tapC	-	-	U	ko:K02653	-	ko00000,ko02035,ko02044	Type II secretion system (T2SS), protein F
MIEGLDIO_00098	0.0	-	-	-	-	-	-	-	-
MIEGLDIO_00099	1.56e-194	pppA	3.4.23.43	-	NOU	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Bacterial Peptidase A24 N-terminal domain
MIEGLDIO_00100	4.39e-244	pilM	-	-	NU	ko:K02662	-	ko00000,ko02035,ko02044	Type IV pilus assembly protein PilM;
MIEGLDIO_00101	6.91e-212	-	-	-	NU	-	-	-	PFAM Fimbrial assembly family protein
MIEGLDIO_00102	3.3e-137	-	-	-	S	ko:K02664	-	ko00000,ko02035,ko02044	Pilus assembly protein, PilO
MIEGLDIO_00103	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
MIEGLDIO_00104	7.9e-312	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MIEGLDIO_00105	4.66e-279	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MIEGLDIO_00106	5.84e-105	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MIEGLDIO_00107	9.14e-55	-	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
MIEGLDIO_00108	2.23e-65	-	-	-	V	-	-	-	DivIVA protein
MIEGLDIO_00109	5.61e-121	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MIEGLDIO_00110	3.52e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MIEGLDIO_00111	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
MIEGLDIO_00112	0.0	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MIEGLDIO_00113	1.36e-287	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MIEGLDIO_00114	4.56e-142	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
MIEGLDIO_00115	1.15e-163	-	-	-	-	-	-	-	-
MIEGLDIO_00116	1.77e-156	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MIEGLDIO_00117	3.39e-167	hisA	5.3.1.16, 5.3.1.24	-	E	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
MIEGLDIO_00118	0.0	glnA2	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MIEGLDIO_00119	6.42e-309	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
MIEGLDIO_00120	1.66e-185	-	-	-	M	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
MIEGLDIO_00121	3.15e-280	-	-	-	EGP	ko:K18567,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
MIEGLDIO_00122	4.33e-153	-	-	-	V	ko:K02003,ko:K09810	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MIEGLDIO_00123	2.04e-152	-	-	-	-	-	-	-	-
MIEGLDIO_00124	3.26e-234	-	-	-	V	-	-	-	N-Acetylmuramoyl-L-alanine amidase
MIEGLDIO_00125	4.73e-244	-	-	-	-	-	-	-	-
MIEGLDIO_00126	0.0	hrpA	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Helicase associated domain (HA2) Add an annotation
MIEGLDIO_00127	1.62e-145	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
MIEGLDIO_00128	0.0	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MIEGLDIO_00129	3.25e-225	ldh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MIEGLDIO_00130	3.34e-192	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MIEGLDIO_00131	6.88e-170	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MIEGLDIO_00132	8.85e-72	-	-	-	M	-	-	-	Lysin motif
MIEGLDIO_00133	2.49e-110	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MIEGLDIO_00134	1.19e-276	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
MIEGLDIO_00135	0.0	-	-	-	L	-	-	-	DNA helicase
MIEGLDIO_00136	9.51e-119	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MIEGLDIO_00137	1.41e-242	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MIEGLDIO_00138	7.27e-82	-	-	-	D	-	-	-	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MIEGLDIO_00139	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding protein, transpeptidase domain protein
MIEGLDIO_00140	2.91e-198	-	-	-	M	-	-	-	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MIEGLDIO_00141	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MIEGLDIO_00142	9.69e-252	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MIEGLDIO_00143	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MIEGLDIO_00144	4.97e-259	ftsW	2.4.1.227	GT28	D	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	Belongs to the SEDS family
MIEGLDIO_00145	1.05e-273	murG	2.4.1.227, 6.3.2.8	GT28	M	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MIEGLDIO_00146	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MIEGLDIO_00147	1.69e-182	ftsQ	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
MIEGLDIO_00148	4.11e-314	-	-	-	G	-	-	-	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
MIEGLDIO_00150	2.39e-277	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
MIEGLDIO_00151	4.74e-212	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
MIEGLDIO_00152	3.68e-276	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MIEGLDIO_00153	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
MIEGLDIO_00154	1.15e-242	dppB	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_00155	5.18e-255	dppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_00156	0.0	-	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MIEGLDIO_00157	5.09e-124	-	-	-	F	-	-	-	NUDIX domain
MIEGLDIO_00158	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
MIEGLDIO_00159	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
MIEGLDIO_00160	1.11e-238	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
MIEGLDIO_00161	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MIEGLDIO_00162	6.43e-126	sigH	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MIEGLDIO_00163	1.25e-49	-	-	-	-	-	-	-	-
MIEGLDIO_00164	9.14e-239	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MIEGLDIO_00165	1.88e-219	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MIEGLDIO_00166	8.17e-114	ybaK	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MIEGLDIO_00167	4.82e-254	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MIEGLDIO_00168	3.27e-142	-	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamin pyrophosphokinase, vitamin B1 binding domain
MIEGLDIO_00169	1.86e-139	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MIEGLDIO_00170	3.31e-35	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
MIEGLDIO_00171	7.76e-81	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MIEGLDIO_00172	2.12e-224	xerD	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	recombinase XerD
MIEGLDIO_00173	8.39e-196	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
MIEGLDIO_00174	6.41e-193	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX hydrolase
MIEGLDIO_00175	0.0	nanT	-	-	U	ko:K03290,ko:K08178,ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
MIEGLDIO_00176	0.0	typA	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
MIEGLDIO_00177	1.01e-135	-	-	-	-	-	-	-	-
MIEGLDIO_00178	1.59e-244	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
MIEGLDIO_00179	6.05e-250	tyrA	1.3.1.12	-	E	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
MIEGLDIO_00180	2.28e-35	-	-	-	-	-	-	-	-
MIEGLDIO_00182	2.28e-219	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
MIEGLDIO_00183	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
MIEGLDIO_00184	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
MIEGLDIO_00185	1.45e-206	dppB	-	-	EP	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_00186	1.18e-223	dppC	-	-	EP	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
MIEGLDIO_00187	0.0	-	-	-	EP	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
MIEGLDIO_00188	3.37e-219	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
MIEGLDIO_00189	3.66e-194	-	-	-	S	-	-	-	Protein of unknown function (DUF3710)
MIEGLDIO_00190	1.09e-171	-	-	-	S	-	-	-	Protein of unknown function (DUF3159)
MIEGLDIO_00191	5.58e-309	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MIEGLDIO_00192	7.16e-97	-	-	-	-	-	-	-	-
MIEGLDIO_00193	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
MIEGLDIO_00194	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MIEGLDIO_00195	0.0	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 9.99
MIEGLDIO_00196	5.47e-151	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Bacterial transferase hexapeptide repeat protein
MIEGLDIO_00197	2.44e-270	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MIEGLDIO_00198	3.96e-292	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MIEGLDIO_00199	2.44e-286	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MIEGLDIO_00200	1.72e-242	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MIEGLDIO_00201	5.2e-311	-	-	-	T	-	-	-	Histidine kinase
MIEGLDIO_00202	1.89e-149	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MIEGLDIO_00203	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
MIEGLDIO_00204	1.02e-164	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MIEGLDIO_00205	1.04e-308	-	-	-	T	-	-	-	Histidine kinase
MIEGLDIO_00206	7.38e-129	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
MIEGLDIO_00207	4.11e-170	-	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MIEGLDIO_00208	9.71e-228	-	-	-	EG	-	-	-	EamA-like transporter family
MIEGLDIO_00209	6.96e-201	ywaC	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
MIEGLDIO_00210	0.0	miaB	2.8.4.3	-	H	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MIEGLDIO_00211	1.6e-246	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MIEGLDIO_00213	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE family protein
MIEGLDIO_00214	1.23e-157	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MIEGLDIO_00215	9.6e-125	cinA	3.5.1.42	-	S	ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
MIEGLDIO_00216	3.83e-104	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MIEGLDIO_00217	7.07e-61	-	-	-	S	-	-	-	Protein of unknown function (DUF3046)
MIEGLDIO_00218	4.97e-271	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MIEGLDIO_00219	2.59e-159	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
MIEGLDIO_00220	5.45e-153	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MIEGLDIO_00221	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MIEGLDIO_00222	3.23e-247	trpD	2.4.2.18	-	F	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MIEGLDIO_00223	4.49e-129	-	-	-	-	-	-	-	-
MIEGLDIO_00224	4.33e-171	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
MIEGLDIO_00225	0.0	pknL	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	PASTA
MIEGLDIO_00226	1.55e-252	idsA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MIEGLDIO_00227	1.05e-151	-	-	-	-	-	-	-	-
MIEGLDIO_00228	3.32e-226	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MIEGLDIO_00229	0.0	gyrB2	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
MIEGLDIO_00230	4.22e-287	-	-	-	G	-	-	-	Major Facilitator Superfamily
MIEGLDIO_00231	7.7e-310	-	-	-	T	-	-	-	Domain of unknown function (DUF4173)
MIEGLDIO_00232	7.86e-103	-	-	-	S	-	-	-	Protein of unknown function (DUF2975)
MIEGLDIO_00233	6.21e-43	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
MIEGLDIO_00234	0.0	lhr	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
MIEGLDIO_00235	0.0	gyrA2	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
MIEGLDIO_00236	2.41e-298	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
MIEGLDIO_00237	3.91e-228	-	-	-	S	-	-	-	Protein of unknown function (DUF3071)
MIEGLDIO_00238	8.5e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4193)
MIEGLDIO_00239	5.02e-110	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
MIEGLDIO_00240	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MIEGLDIO_00241	4.64e-254	ppiA	5.2.1.8	-	G	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MIEGLDIO_00243	6.48e-91	-	-	-	-	-	-	-	-
MIEGLDIO_00245	1.26e-34	-	-	-	-	-	-	-	-
MIEGLDIO_00246	2.32e-280	-	-	-	S	-	-	-	Helix-turn-helix domain
MIEGLDIO_00247	8.54e-58	-	-	-	-	-	-	-	-
MIEGLDIO_00248	3.78e-122	-	-	-	S	-	-	-	Transcription factor WhiB
MIEGLDIO_00249	1.39e-157	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	AAA domain
MIEGLDIO_00250	5.76e-52	-	-	-	-	-	-	-	-
MIEGLDIO_00251	1.35e-177	-	-	-	-	ko:K03646	-	ko00000,ko02000	-
MIEGLDIO_00252	0.0	-	-	-	D	-	-	-	Cell surface antigen C-terminus
MIEGLDIO_00253	0.0	-	-	-	O	-	-	-	Subtilase family
MIEGLDIO_00254	1.17e-268	-	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
MIEGLDIO_00255	2.21e-197	-	-	-	D	-	-	-	Cell surface antigen C-terminus
MIEGLDIO_00256	1.43e-188	-	-	-	-	-	-	-	-
MIEGLDIO_00257	3.7e-85	-	-	-	S	-	-	-	PrgI family protein
MIEGLDIO_00258	0.0	-	-	-	U	-	-	-	type IV secretory pathway VirB4
MIEGLDIO_00259	0.0	-	-	-	M	-	-	-	CHAP domain
MIEGLDIO_00260	4.31e-128	-	-	-	-	-	-	-	-
MIEGLDIO_00261	2.86e-270	-	-	-	-	ko:K03646	-	ko00000,ko02000	-
MIEGLDIO_00262	0.0	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	Type IV secretory system Conjugative DNA transfer
MIEGLDIO_00263	1.52e-68	-	-	-	-	-	-	-	-
MIEGLDIO_00264	1.33e-71	-	-	-	-	-	-	-	-
MIEGLDIO_00265	8.31e-223	-	-	-	-	-	-	-	-
MIEGLDIO_00266	0.0	-	-	-	-	-	-	-	-
MIEGLDIO_00267	2.74e-185	-	-	-	S	-	-	-	Protein of unknown function (DUF3801)
MIEGLDIO_00268	0.0	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
MIEGLDIO_00269	6.14e-73	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
MIEGLDIO_00270	1.03e-28	-	-	-	-	-	-	-	-
MIEGLDIO_00271	3.96e-61	-	-	-	-	-	-	-	-
MIEGLDIO_00272	0.0	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	DNA topoisomerase
MIEGLDIO_00273	3.7e-108	-	-	-	-	-	-	-	-
MIEGLDIO_00274	8.35e-14	-	-	-	-	-	-	-	-
MIEGLDIO_00275	4.78e-180	-	-	-	S	-	-	-	Fic/DOC family
MIEGLDIO_00278	1.62e-74	-	-	-	K	-	-	-	acetyltransferase
MIEGLDIO_00279	3.29e-54	-	-	-	S	-	-	-	ASCH
MIEGLDIO_00281	2.99e-15	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
MIEGLDIO_00283	6.5e-35	-	-	-	-	-	-	-	-
MIEGLDIO_00284	4.33e-186	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
MIEGLDIO_00285	0.0	intA	-	-	L	-	-	-	Phage integrase family
MIEGLDIO_00286	6.87e-311	dinF	-	-	V	-	-	-	MatE
MIEGLDIO_00287	0.0	-	-	-	S	-	-	-	LPXTG-motif cell wall anchor domain protein
MIEGLDIO_00289	4.26e-86	-	-	-	L	-	-	-	Helix-turn-helix domain
MIEGLDIO_00290	2.15e-130	-	-	-	V	-	-	-	Abi-like protein
MIEGLDIO_00292	1.52e-98	-	-	-	-	-	-	-	-
MIEGLDIO_00293	1.59e-144	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_00294	4.13e-188	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MIEGLDIO_00295	3.14e-192	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
MIEGLDIO_00296	1.35e-199	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MIEGLDIO_00297	1.58e-286	-	-	-	S	-	-	-	Peptidase dimerisation domain
MIEGLDIO_00298	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MIEGLDIO_00299	1.28e-41	-	-	-	-	-	-	-	-
MIEGLDIO_00300	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
MIEGLDIO_00301	1.76e-210	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MIEGLDIO_00302	3.3e-102	-	-	-	S	-	-	-	Protein of unknown function (DUF3000)
MIEGLDIO_00303	1.7e-299	rnd	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
MIEGLDIO_00304	3.45e-301	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MIEGLDIO_00305	5.37e-168	-	-	-	S	-	-	-	DUF218 domain
MIEGLDIO_00306	5.63e-164	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
MIEGLDIO_00307	1.75e-211	-	1.1.1.91	-	C	ko:K05882	-	ko00000,ko01000	Aldo/keto reductase family
MIEGLDIO_00308	4.1e-105	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin domain
MIEGLDIO_00309	1.46e-191	-	-	-	S	-	-	-	phosphoesterase or phosphohydrolase
MIEGLDIO_00311	1.28e-30	-	-	-	-	-	-	-	-
MIEGLDIO_00312	1.73e-144	-	-	-	S	-	-	-	Putative inner membrane protein (DUF1819)
MIEGLDIO_00313	2.02e-56	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative DNA-binding domain
MIEGLDIO_00314	6.17e-73	-	-	-	S	-	-	-	MazG-like family
MIEGLDIO_00315	0.0	-	-	-	L	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
MIEGLDIO_00316	3.25e-40	-	-	-	-	-	-	-	-
MIEGLDIO_00317	6.51e-162	-	-	-	S	-	-	-	alpha beta
MIEGLDIO_00318	4.45e-109	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MIEGLDIO_00319	5.06e-234	-	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MIEGLDIO_00320	4.94e-149	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
MIEGLDIO_00321	6.53e-53	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	homocysteine catabolic process
MIEGLDIO_00322	0.0	-	-	-	KL	-	-	-	Psort location Cytoplasmic, score 8.87
MIEGLDIO_00323	1.3e-133	-	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MIEGLDIO_00324	0.0	-	-	-	GP	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MIEGLDIO_00325	3.73e-63	-	-	-	J	ko:K07574	-	ko00000,ko03009	CRS1_YhbY
MIEGLDIO_00326	2.23e-188	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MIEGLDIO_00327	9.03e-258	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
MIEGLDIO_00328	3.28e-181	ppgK	2.7.1.2, 2.7.1.63	-	GK	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MIEGLDIO_00329	2.89e-281	-	-	-	E	-	-	-	Aminotransferase class I and II
MIEGLDIO_00330	6.33e-186	-	-	-	P	ko:K16784	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MIEGLDIO_00331	0.0	-	2.8.2.22	-	S	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
MIEGLDIO_00332	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MIEGLDIO_00333	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
MIEGLDIO_00334	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MIEGLDIO_00335	1.12e-258	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MIEGLDIO_00336	3.77e-109	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MIEGLDIO_00337	0.0	ykoD	-	-	P	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MIEGLDIO_00338	1.27e-186	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MIEGLDIO_00339	0.0	argE	-	-	E	-	-	-	Peptidase dimerisation domain
MIEGLDIO_00340	4.31e-127	-	-	-	S	-	-	-	Protein of unknown function (DUF3043)
MIEGLDIO_00341	7.43e-314	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MIEGLDIO_00342	5.03e-183	-	-	-	S	-	-	-	Domain of unknown function (DUF4191)
MIEGLDIO_00343	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MIEGLDIO_00344	1.52e-19	-	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
MIEGLDIO_00345	9.27e-146	-	-	-	L	-	-	-	Uracil DNA glycosylase superfamily
MIEGLDIO_00346	2.76e-15	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	HNH endonuclease
MIEGLDIO_00348	2.41e-24	-	-	-	-	-	-	-	-
MIEGLDIO_00350	2.39e-121	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Possible lysine decarboxylase
MIEGLDIO_00352	8.72e-259	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MIEGLDIO_00353	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Phenylalanyl-tRNA synthetase beta
MIEGLDIO_00354	7.69e-148	-	-	-	-	-	-	-	-
MIEGLDIO_00355	5.5e-262	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MIEGLDIO_00356	7.86e-266	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MIEGLDIO_00357	5.02e-228	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
MIEGLDIO_00358	3.91e-305	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
MIEGLDIO_00359	2.32e-235	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MIEGLDIO_00360	1.91e-109	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
MIEGLDIO_00361	4.33e-303	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
MIEGLDIO_00362	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
MIEGLDIO_00363	4.08e-123	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MIEGLDIO_00364	1.01e-181	-	-	-	S	-	-	-	Putative ABC-transporter type IV
MIEGLDIO_00365	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
MIEGLDIO_00366	6.35e-313	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MIEGLDIO_00367	1.95e-225	-	-	-	L	-	-	-	Tetratricopeptide repeat
MIEGLDIO_00368	7.18e-238	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
MIEGLDIO_00369	1.58e-162	tlyA	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
MIEGLDIO_00370	1.16e-78	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MIEGLDIO_00371	8.09e-83	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
MIEGLDIO_00372	5.31e-90	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma factor, sigma-70 family
MIEGLDIO_00373	1.06e-149	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
MIEGLDIO_00374	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
MIEGLDIO_00375	7.95e-222	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MIEGLDIO_00376	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MIEGLDIO_00377	1.34e-153	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MIEGLDIO_00378	8.16e-153	-	-	-	S	-	-	-	ABC-2 family transporter protein
MIEGLDIO_00379	1.6e-220	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MIEGLDIO_00380	5.08e-76	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
MIEGLDIO_00381	0.0	-	-	-	S	-	-	-	Histidine phosphatase superfamily (branch 2)
MIEGLDIO_00382	1.04e-122	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
MIEGLDIO_00383	1.73e-30	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MIEGLDIO_00384	1.75e-117	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Redoxin
MIEGLDIO_00386	8.74e-17	-	2.7.1.53	-	G	ko:K00880	ko00040,ko00053,map00040,map00053	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
MIEGLDIO_00387	2e-206	-	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
MIEGLDIO_00388	7.82e-182	-	-	-	-	-	-	-	-
MIEGLDIO_00389	4.61e-221	-	-	-	G	-	-	-	Fic/DOC family
MIEGLDIO_00390	1.49e-138	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
MIEGLDIO_00391	1.69e-296	-	-	-	EGP	-	-	-	Transporter major facilitator family protein
MIEGLDIO_00392	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase N terminus
MIEGLDIO_00393	0.0	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MIEGLDIO_00394	5.01e-311	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MIEGLDIO_00395	5.54e-131	-	-	-	-	-	-	-	-
MIEGLDIO_00396	1.1e-180	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MIEGLDIO_00397	1.67e-241	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MIEGLDIO_00399	5.07e-157	-	-	-	-	-	-	-	-
MIEGLDIO_00400	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	long-chain-fatty acid CoA ligase
MIEGLDIO_00401	1.22e-107	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MIEGLDIO_00402	7.95e-183	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MIEGLDIO_00403	6.23e-184	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MIEGLDIO_00405	2.04e-172	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MIEGLDIO_00406	6.26e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MIEGLDIO_00407	5.62e-228	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
MIEGLDIO_00408	1.12e-287	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MIEGLDIO_00409	1.61e-177	hisF	4.1.3.27	-	E	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MIEGLDIO_00410	1.12e-95	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MIEGLDIO_00411	0.0	trpE	4.1.3.27	-	E	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MIEGLDIO_00412	0.0	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MIEGLDIO_00413	2.25e-207	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MIEGLDIO_00414	2.79e-230	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MIEGLDIO_00415	2.25e-137	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3-epimerase
MIEGLDIO_00416	1.2e-54	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-ATP pyrophosphohydrolase
MIEGLDIO_00417	1.24e-199	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
MIEGLDIO_00418	8.44e-134	pgsA2	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MIEGLDIO_00419	3.77e-221	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
MIEGLDIO_00420	2.68e-64	sbp	-	-	S	-	-	-	Protein of unknown function (DUF1290)
MIEGLDIO_00421	3.22e-182	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
MIEGLDIO_00422	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MIEGLDIO_00423	2.88e-144	pgsA1	2.7.8.11, 2.7.8.5	-	I	ko:K00995,ko:K00999	ko00562,ko00564,ko01100,ko04070,map00562,map00564,map01100,map04070	ko00000,ko00001,ko01000	CDP-alcohol phosphatidyltransferase
MIEGLDIO_00424	2.38e-172	yebC	-	-	K	-	-	-	transcriptional regulatory protein
MIEGLDIO_00425	2.73e-129	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MIEGLDIO_00426	1.34e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MIEGLDIO_00427	5.61e-255	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MIEGLDIO_00428	1.05e-80	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
MIEGLDIO_00429	5.27e-130	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MIEGLDIO_00430	1.11e-280	sucC	6.2.1.5	-	F	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MIEGLDIO_00431	1.1e-205	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MIEGLDIO_00432	0.0	-	-	-	-	-	-	-	-
MIEGLDIO_00433	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
MIEGLDIO_00434	1.69e-48	-	-	-	-	-	-	-	-
MIEGLDIO_00435	1.97e-206	-	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MIEGLDIO_00436	9.79e-184	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MIEGLDIO_00437	0.0	der	-	-	F	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MIEGLDIO_00438	8.64e-92	-	-	-	-	-	-	-	-
MIEGLDIO_00440	0.0	ugp	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MIEGLDIO_00441	0.0	-	-	-	K	-	-	-	WYL domain
MIEGLDIO_00442	2.4e-73	-	-	-	-	-	-	-	-
MIEGLDIO_00443	0.0	helY	-	-	L	ko:K03727	-	ko00000,ko01000	DEAD DEAH box helicase
MIEGLDIO_00444	2.24e-81	rbpA	-	-	K	-	-	-	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
MIEGLDIO_00445	5.93e-181	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
MIEGLDIO_00446	1.54e-80	-	-	-	-	-	-	-	-
MIEGLDIO_00447	8.77e-144	merR2	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MIEGLDIO_00448	9.05e-98	garA	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
MIEGLDIO_00449	3.74e-48	-	-	-	-	-	-	-	-
MIEGLDIO_00457	2.29e-199	-	-	-	S	-	-	-	PAC2 family
MIEGLDIO_00458	1.44e-199	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MIEGLDIO_00459	6.46e-201	-	-	-	G	-	-	-	Fructosamine kinase
MIEGLDIO_00460	6.98e-265	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MIEGLDIO_00461	7.99e-251	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MIEGLDIO_00462	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
MIEGLDIO_00463	5.47e-259	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MIEGLDIO_00464	6.46e-54	nadR	-	-	H	-	-	-	ATPase kinase involved in NAD metabolism
MIEGLDIO_00465	7.86e-137	-	-	-	H	ko:K03811	-	ko00000,ko02000	Nicotinamide mononucleotide transporter
MIEGLDIO_00467	0.0	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase, class I II
MIEGLDIO_00468	1.58e-208	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MIEGLDIO_00469	2.47e-44	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
MIEGLDIO_00470	4.01e-191	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MIEGLDIO_00471	3.72e-281	pgk	2.7.2.3, 5.3.1.1	-	F	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
MIEGLDIO_00472	2.1e-219	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MIEGLDIO_00473	4.41e-218	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MIEGLDIO_00474	1.7e-233	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate dehydrogenase substrate binding domain
MIEGLDIO_00475	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MIEGLDIO_00476	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MIEGLDIO_00477	2.14e-282	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MIEGLDIO_00478	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MIEGLDIO_00479	3.96e-180	-	-	-	S	-	-	-	Domain of unknown function (DUF4194)
MIEGLDIO_00480	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MIEGLDIO_00481	2.77e-19	-	-	-	-	-	-	-	-
MIEGLDIO_00483	4.53e-88	ogt	2.1.1.63	-	L	ko:K00567,ko:K07443	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MIEGLDIO_00484	5.54e-144	pncA	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Isochorismatase family
MIEGLDIO_00485	0.0	ybiT	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
MIEGLDIO_00486	6.85e-216	-	-	-	S	-	-	-	IMP dehydrogenase activity
MIEGLDIO_00487	0.0	-	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MIEGLDIO_00488	7.76e-186	mazG	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	Psort location Cytoplasmic, score 8.87
MIEGLDIO_00489	1.59e-195	-	-	-	-	-	-	-	-
MIEGLDIO_00490	1.62e-141	-	-	-	-	ko:K03646	-	ko00000,ko02000	-
MIEGLDIO_00493	5.23e-233	-	-	-	P	-	-	-	Cation efflux family
MIEGLDIO_00494	1.18e-92	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
MIEGLDIO_00495	1.06e-281	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
MIEGLDIO_00496	3.77e-185	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
MIEGLDIO_00497	4.33e-220	adh	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
MIEGLDIO_00498	2.39e-93	-	-	-	K	-	-	-	MerR family regulatory protein
MIEGLDIO_00499	3.51e-154	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MIEGLDIO_00500	4.34e-237	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MIEGLDIO_00501	4.62e-152	yoaP	-	-	E	-	-	-	YoaP-like
MIEGLDIO_00503	1.13e-250	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MIEGLDIO_00504	1.73e-133	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	FR47-like protein
MIEGLDIO_00505	6.89e-190	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Glycoprotease family
MIEGLDIO_00506	7.17e-119	tsaE	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
MIEGLDIO_00507	3.52e-227	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MIEGLDIO_00508	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
MIEGLDIO_00509	4.58e-137	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
MIEGLDIO_00510	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MIEGLDIO_00511	1.93e-182	-	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MIEGLDIO_00512	1.48e-219	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MIEGLDIO_00513	1.72e-210	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
MIEGLDIO_00516	0.0	-	-	-	M	-	-	-	domain protein
MIEGLDIO_00517	4.75e-92	pdxH	-	-	S	ko:K07006	-	ko00000	Pfam:Pyridox_oxidase
MIEGLDIO_00518	1.2e-298	-	-	-	K	-	-	-	Fic/DOC family
MIEGLDIO_00520	1.08e-156	-	-	-	-	-	-	-	-
MIEGLDIO_00521	7.33e-183	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
MIEGLDIO_00522	3.94e-88	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MIEGLDIO_00523	2.71e-316	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MIEGLDIO_00524	1.7e-91	-	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MIEGLDIO_00525	5.78e-139	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease, DNA polymerase III, epsilon subunit family
MIEGLDIO_00526	1.07e-265	guaB3	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase family protein
MIEGLDIO_00527	1.58e-305	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
MIEGLDIO_00528	0.0	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
MIEGLDIO_00529	0.0	fadD1	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
MIEGLDIO_00530	8.01e-124	-	-	-	M	-	-	-	Peptidase family M23
MIEGLDIO_00531	1.81e-81	-	-	-	-	-	-	-	-
MIEGLDIO_00534	5.36e-161	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MIEGLDIO_00535	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MIEGLDIO_00536	3.2e-157	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MIEGLDIO_00537	4.13e-180	-	-	-	S	-	-	-	SdpI/YhfL protein family
MIEGLDIO_00538	6.64e-67	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MIEGLDIO_00539	8.63e-156	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
MIEGLDIO_00540	1.09e-277	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
MIEGLDIO_00541	4.36e-89	arsC	1.20.4.1, 2.8.4.2	-	T	ko:K03741,ko:K18701	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MIEGLDIO_00542	9.59e-141	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MIEGLDIO_00543	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MIEGLDIO_00544	3.49e-209	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
MIEGLDIO_00545	9.36e-160	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MIEGLDIO_00546	8.22e-230	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MIEGLDIO_00547	5.08e-198	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
MIEGLDIO_00548	1.44e-228	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
MIEGLDIO_00549	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MIEGLDIO_00550	1.06e-96	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
MIEGLDIO_00551	2.43e-240	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MIEGLDIO_00552	0.0	glnE	2.7.7.42, 2.7.7.89	-	H	ko:K00982	-	ko00000,ko01000	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
MIEGLDIO_00553	6.46e-28	-	-	-	-	-	-	-	-
MIEGLDIO_00554	6.52e-236	-	-	-	U	ko:K10547	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
MIEGLDIO_00555	0.0	araG	3.6.3.17	-	G	ko:K10548	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MIEGLDIO_00556	1.74e-239	-	-	-	G	ko:K10546	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
MIEGLDIO_00557	2.95e-226	-	-	-	GK	-	-	-	ROK family
MIEGLDIO_00558	6.39e-159	-	3.6.3.17	-	G	ko:K02056,ko:K10545	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MIEGLDIO_00559	3.48e-38	-	-	-	-	-	-	-	-
MIEGLDIO_00560	6.36e-51	glnE	2.7.7.42, 2.7.7.89	-	H	ko:K00982	-	ko00000,ko01000	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
MIEGLDIO_00561	4.74e-201	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
MIEGLDIO_00562	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MIEGLDIO_00563	1.16e-39	-	-	-	S	-	-	-	Putative phage holin Dp-1
MIEGLDIO_00564	1.19e-246	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
MIEGLDIO_00565	4.62e-23	-	-	-	-	-	-	-	-
MIEGLDIO_00566	6.02e-190	-	-	-	L	-	-	-	DNA integration
MIEGLDIO_00568	8.42e-25	-	-	-	-	-	-	-	-
MIEGLDIO_00570	9.03e-94	-	-	-	-	-	-	-	-
MIEGLDIO_00574	6.81e-142	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
MIEGLDIO_00575	1.65e-152	-	-	-	-	-	-	-	-
MIEGLDIO_00576	0.0	-	-	-	S	-	-	-	phage tail tape measure protein
MIEGLDIO_00578	1.57e-84	-	-	-	-	-	-	-	-
MIEGLDIO_00579	1.25e-134	-	-	-	-	-	-	-	-
MIEGLDIO_00580	2.76e-81	-	-	-	-	-	-	-	-
MIEGLDIO_00581	6.12e-44	-	-	-	-	-	-	-	-
MIEGLDIO_00582	1.2e-61	-	-	-	-	-	-	-	-
MIEGLDIO_00583	8.24e-83	-	-	-	S	-	-	-	Phage protein Gp19/Gp15/Gp42
MIEGLDIO_00585	1.1e-198	-	-	-	V	-	-	-	Phage capsid family
MIEGLDIO_00586	6.89e-100	-	-	-	-	-	-	-	-
MIEGLDIO_00588	2.39e-139	-	-	-	-	-	-	-	-
MIEGLDIO_00589	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
MIEGLDIO_00590	1.75e-288	-	-	-	S	-	-	-	Terminase
MIEGLDIO_00591	1.44e-48	-	-	-	-	-	-	-	-
MIEGLDIO_00592	4.66e-69	-	-	-	V	-	-	-	HNH nucleases
MIEGLDIO_00593	1.94e-161	-	-	-	J	-	-	-	tRNA 5'-leader removal
MIEGLDIO_00594	3.77e-23	-	-	-	-	-	-	-	-
MIEGLDIO_00598	2.1e-60	-	-	-	A	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MIEGLDIO_00599	2.35e-101	-	-	-	V	-	-	-	HNH endonuclease
MIEGLDIO_00600	1.79e-34	-	-	-	-	-	-	-	-
MIEGLDIO_00601	3.01e-101	-	-	-	K	-	-	-	Transcriptional regulator
MIEGLDIO_00602	6.26e-104	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
MIEGLDIO_00604	1.61e-44	-	-	-	-	-	-	-	-
MIEGLDIO_00605	2.44e-05	-	-	-	-	-	-	-	-
MIEGLDIO_00608	1.83e-49	-	-	-	-	-	-	-	-
MIEGLDIO_00610	2.95e-154	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
MIEGLDIO_00614	9.17e-26	-	-	-	-	-	-	-	-
MIEGLDIO_00615	1.35e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF3800)
MIEGLDIO_00616	1.96e-18	-	-	-	-	-	-	-	-
MIEGLDIO_00617	1.53e-80	-	-	-	-	-	-	-	-
MIEGLDIO_00618	7.41e-45	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	site-specific DNA-methyltransferase (adenine-specific) activity
MIEGLDIO_00619	8.08e-172	-	-	-	-	-	-	-	-
MIEGLDIO_00620	3.72e-86	-	-	-	-	-	-	-	-
MIEGLDIO_00621	2.24e-305	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
MIEGLDIO_00622	1.67e-128	sixA	-	-	T	ko:K08296	-	ko00000,ko01000	Phosphoglycerate mutase family
MIEGLDIO_00623	9.73e-254	trmI	2.1.1.219, 2.1.1.220	-	J	ko:K07442	-	ko00000,ko01000,ko03016	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MIEGLDIO_00624	2.73e-203	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MIEGLDIO_00625	0.0	glgA	2.4.1.342	GT4	G	ko:K16148	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Starch synthase catalytic domain
MIEGLDIO_00626	1.83e-96	-	-	-	-	-	-	-	-
MIEGLDIO_00627	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MIEGLDIO_00628	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase NADPH large subunit
MIEGLDIO_00629	7.78e-298	-	-	-	F	-	-	-	Psort location CytoplasmicMembrane, score 10.00
MIEGLDIO_00630	7.44e-278	-	-	-	H	-	-	-	long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase
MIEGLDIO_00631	0.0	-	-	-	C	-	-	-	Acyl-CoA reductase (LuxC)
MIEGLDIO_00632	9.78e-188	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
MIEGLDIO_00633	1.28e-297	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
MIEGLDIO_00634	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MIEGLDIO_00635	7.89e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MIEGLDIO_00636	3.02e-174	-	-	-	S	-	-	-	UPF0126 domain
MIEGLDIO_00637	8.14e-290	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Amino-transferase class IV
MIEGLDIO_00639	4.42e-76	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MIEGLDIO_00640	1e-76	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MIEGLDIO_00641	4.92e-120	-	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MIEGLDIO_00642	1.29e-127	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MIEGLDIO_00643	1.08e-249	-	-	-	S	ko:K06889	-	ko00000	alpha beta
MIEGLDIO_00644	9.97e-36	yhjX	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major facilitator Superfamily
MIEGLDIO_00645	3.74e-41	-	-	-	EGP	ko:K08177,ko:K19577	-	ko00000,ko02000	Major facilitator Superfamily
MIEGLDIO_00646	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MIEGLDIO_00647	2.96e-242	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MIEGLDIO_00649	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MIEGLDIO_00650	2.67e-96	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
MIEGLDIO_00651	3.96e-53	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
MIEGLDIO_00653	5.26e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MIEGLDIO_00654	1.59e-286	-	-	-	G	-	-	-	Transmembrane secretion effector
MIEGLDIO_00656	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MIEGLDIO_00657	0.0	pntB	1.6.1.2	-	C	ko:K00325	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MIEGLDIO_00658	1.02e-57	pntAB	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	4TM region of pyridine nucleotide transhydrogenase, mitoch
MIEGLDIO_00659	3.43e-260	pntA	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	NAD(P) transhydrogenase subunit alpha part 1 K00324
MIEGLDIO_00660	0.0	fadD2	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
MIEGLDIO_00661	2.58e-228	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MIEGLDIO_00662	0.0	corC	-	-	S	-	-	-	CBS domain
MIEGLDIO_00663	3.28e-133	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MIEGLDIO_00664	2.86e-267	phoH	-	-	T	ko:K06217	-	ko00000	PhoH-like protein
MIEGLDIO_00665	8.96e-75	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
MIEGLDIO_00666	9.78e-188	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MIEGLDIO_00668	3.08e-207	spoU2	-	-	J	-	-	-	SpoU rRNA Methylase family
MIEGLDIO_00669	5.57e-310	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MIEGLDIO_00670	1.6e-140	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MIEGLDIO_00671	9.63e-128	iscU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
MIEGLDIO_00672	1.86e-304	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MIEGLDIO_00673	1.14e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
MIEGLDIO_00674	2.61e-300	sufD	-	-	O	ko:K09015	-	ko00000	FeS assembly protein SufD
MIEGLDIO_00675	0.0	sufB	-	-	O	ko:K09014	-	ko00000	FeS assembly protein SufB
MIEGLDIO_00676	0.0	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
MIEGLDIO_00677	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MIEGLDIO_00678	0.0	-	3.2.1.1, 3.2.1.41	CBM48,GH13	M	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	Aamy_C
MIEGLDIO_00679	3.9e-105	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
MIEGLDIO_00680	0.0	aroB	2.7.1.71, 4.2.3.4	-	H	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MIEGLDIO_00681	1.64e-282	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MIEGLDIO_00682	1.06e-94	-	3.4.23.43	-	S	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
MIEGLDIO_00683	9.58e-253	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MIEGLDIO_00684	1.06e-106	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MIEGLDIO_00685	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MIEGLDIO_00686	6.83e-50	-	-	-	-	-	-	-	-
MIEGLDIO_00687	8.09e-79	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
MIEGLDIO_00688	9.46e-167	-	5.4.2.12	-	G	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
MIEGLDIO_00689	1.97e-74	-	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
MIEGLDIO_00690	3.17e-142	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MIEGLDIO_00691	7.41e-192	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MIEGLDIO_00692	7.13e-276	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MIEGLDIO_00693	3.23e-80	-	-	-	S	-	-	-	Domain of unknown function (DUF4418)
MIEGLDIO_00694	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MIEGLDIO_00695	2.66e-138	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MIEGLDIO_00696	6.08e-312	pbuX	-	-	F	ko:K03458	-	ko00000	Permease family
MIEGLDIO_00697	0.0	yrhL	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
MIEGLDIO_00698	1.33e-294	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MIEGLDIO_00699	0.0	pta	2.3.1.8	-	C	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphate acetyltransferase
MIEGLDIO_00700	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
MIEGLDIO_00701	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MIEGLDIO_00702	8.04e-101	-	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MIEGLDIO_00703	2.64e-92	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MIEGLDIO_00704	0.0	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MIEGLDIO_00706	9.65e-271	-	-	-	-	-	-	-	-
MIEGLDIO_00707	0.0	glgX	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
MIEGLDIO_00708	5.68e-155	-	-	-	L	-	-	-	NUDIX domain
MIEGLDIO_00709	3.48e-215	-	-	-	L	-	-	-	NIF3 (NGG1p interacting factor 3)
MIEGLDIO_00710	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MIEGLDIO_00711	2.47e-155	pdtaR	-	-	T	ko:K22010	-	ko00000,ko00002,ko02022	Response regulator receiver domain protein
MIEGLDIO_00712	2.57e-209	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
MIEGLDIO_00713	3.56e-133	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MIEGLDIO_00714	3.95e-85	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type i restriction
MIEGLDIO_00715	7.08e-73	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
MIEGLDIO_00716	5.22e-305	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	HsdM N-terminal domain
MIEGLDIO_00717	0.0	-	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
MIEGLDIO_00718	1.68e-44	-	-	-	F	-	-	-	DNA helicase
MIEGLDIO_00719	4.5e-132	tcyA/tcyB	-	-	E	ko:K02029,ko:K02030,ko:K02424,ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_00720	7.84e-159	-	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Bacterial periplasmic substrate-binding proteins
MIEGLDIO_00721	3.03e-147	ehuA	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MIEGLDIO_00722	6.12e-249	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
MIEGLDIO_00724	1.44e-25	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MIEGLDIO_00726	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
MIEGLDIO_00727	2.78e-225	terC	-	-	P	ko:K05794	-	ko00000	Integral membrane protein, TerC family
MIEGLDIO_00728	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MIEGLDIO_00729	1.09e-149	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MIEGLDIO_00730	0.0	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MIEGLDIO_00731	9.54e-208	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MIEGLDIO_00732	2.02e-231	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
MIEGLDIO_00733	3.48e-199	-	-	-	P	ko:K02074	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MIEGLDIO_00734	3.19e-179	znuB	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
MIEGLDIO_00735	8.88e-112	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MIEGLDIO_00736	8.46e-133	carD	-	-	K	ko:K07736	-	ko00000,ko03000	CarD-like/TRCF domain
MIEGLDIO_00737	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MIEGLDIO_00738	1.17e-163	cseB	-	-	T	-	-	-	Response regulator receiver domain protein
MIEGLDIO_00739	1.99e-238	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
MIEGLDIO_00740	3.28e-178	pyrE_1	-	-	S	-	-	-	Phosphoribosyl transferase domain
MIEGLDIO_00741	1.04e-195	-	-	-	T	-	-	-	Eukaryotic phosphomannomutase
MIEGLDIO_00742	6.14e-93	-	-	-	S	-	-	-	Zincin-like metallopeptidase
MIEGLDIO_00743	1.26e-288	-	-	-	-	-	-	-	-
MIEGLDIO_00744	0.0	-	-	-	S	-	-	-	Glycosyl transferase, family 2
MIEGLDIO_00745	5.69e-72	whiB2	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
MIEGLDIO_00746	2.38e-299	yvhJ	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
MIEGLDIO_00748	7.9e-218	lytR2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
MIEGLDIO_00749	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
MIEGLDIO_00750	3.32e-61	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
MIEGLDIO_00751	0.0	pdtaS	2.7.13.3	-	T	ko:K00936	-	ko00000,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
MIEGLDIO_00752	1.49e-197	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
MIEGLDIO_00753	2.04e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MIEGLDIO_00754	1.12e-95	fkbP	5.2.1.8	-	G	ko:K01802	-	ko00000,ko01000	Peptidyl-prolyl cis-trans
MIEGLDIO_00755	0.0	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
MIEGLDIO_00756	2.5e-117	-	-	-	-	-	-	-	-
MIEGLDIO_00757	1.51e-89	-	-	-	P	-	-	-	Major Facilitator Superfamily
MIEGLDIO_00759	7.44e-232	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
MIEGLDIO_00760	9.37e-133	-	-	-	S	ko:K09009	-	ko00000	Protein of unknown function (DUF501)
MIEGLDIO_00761	4.86e-97	-	-	-	D	-	-	-	Septum formation initiator
MIEGLDIO_00762	7.13e-313	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MIEGLDIO_00763	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MIEGLDIO_00764	1.42e-145	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MIEGLDIO_00765	1.08e-121	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
MIEGLDIO_00766	0.0	-	-	-	S	ko:K09118	-	ko00000	Uncharacterised protein family (UPF0182)
MIEGLDIO_00767	1.68e-230	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
MIEGLDIO_00768	1.2e-53	-	-	-	S	-	-	-	Selenoprotein, putative
MIEGLDIO_00769	0.0	cstA	-	-	T	ko:K06200	-	ko00000	5TM C-terminal transporter carbon starvation CstA
MIEGLDIO_00770	1.96e-71	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
MIEGLDIO_00771	3.78e-181	-	-	-	E	-	-	-	AzlC protein
MIEGLDIO_00772	4.96e-134	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
MIEGLDIO_00773	3.28e-105	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MIEGLDIO_00774	1.37e-185	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
MIEGLDIO_00775	6.8e-227	opcA	-	-	G	-	-	-	Glucose-6-phosphate dehydrogenase subunit
MIEGLDIO_00776	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MIEGLDIO_00777	1.56e-276	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
MIEGLDIO_00778	2.8e-187	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MIEGLDIO_00779	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MIEGLDIO_00780	0.0	lysX	-	-	S	-	-	-	Uncharacterised conserved protein (DUF2156)
MIEGLDIO_00781	3.74e-303	-	-	-	S	-	-	-	Putative esterase
MIEGLDIO_00782	4.94e-183	-	-	-	V	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MIEGLDIO_00783	2.75e-172	-	-	-	V	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
MIEGLDIO_00784	0.0	-	-	-	JKL	-	-	-	helicase superfamily c-terminal domain
MIEGLDIO_00785	5.4e-164	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
MIEGLDIO_00786	2.42e-298	rutG	-	-	F	ko:K02824,ko:K03458	-	ko00000,ko02000	Permease family
MIEGLDIO_00787	3.19e-200	-	-	-	G	-	-	-	Phosphoglycerate mutase family
MIEGLDIO_00788	1.34e-181	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MIEGLDIO_00789	2.6e-176	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
MIEGLDIO_00790	7.07e-120	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
MIEGLDIO_00791	3.76e-145	-	-	-	F	-	-	-	uridine kinase
MIEGLDIO_00792	1.54e-220	-	-	-	C	ko:K07138	-	ko00000	Domain of unknown function (DUF362)
MIEGLDIO_00793	2.03e-287	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter family protein
MIEGLDIO_00794	6.23e-223	-	-	-	S	-	-	-	Conserved hypothetical protein 698
MIEGLDIO_00795	1.89e-169	-	-	-	-	-	-	-	-
MIEGLDIO_00796	2.83e-20	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
MIEGLDIO_00799	2.7e-17	-	-	-	-	-	-	-	-
MIEGLDIO_00800	9.65e-79	yccF	-	-	S	-	-	-	Inner membrane component domain
MIEGLDIO_00801	3.84e-258	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MIEGLDIO_00802	6.74e-175	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MIEGLDIO_00803	0.0	pip	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	alpha/beta hydrolase fold
MIEGLDIO_00804	0.0	-	-	-	T	-	-	-	Histidine kinase
MIEGLDIO_00805	2.47e-168	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MIEGLDIO_00806	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
MIEGLDIO_00807	1.28e-182	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MIEGLDIO_00808	2.42e-245	asnC	-	-	K	ko:K03718	-	ko00000,ko03000	helix_turn_helix ASNC type
MIEGLDIO_00809	1.1e-192	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MIEGLDIO_00810	0.0	ykoD	-	-	P	ko:K16784,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MIEGLDIO_00811	1.88e-124	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
MIEGLDIO_00812	0.0	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Aminotransferase class-V
MIEGLDIO_00813	2.14e-211	pdxY	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
MIEGLDIO_00814	1.85e-108	yraN	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
MIEGLDIO_00815	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
MIEGLDIO_00816	0.0	dprA	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
MIEGLDIO_00817	0.0	sdhA	1.3.5.1, 1.3.5.4, 1.4.3.16	-	C	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Succinate dehydrogenase flavoprotein subunit
MIEGLDIO_00818	4.82e-226	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
MIEGLDIO_00819	1.23e-151	safC	-	-	S	-	-	-	O-methyltransferase
MIEGLDIO_00820	2.92e-315	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MIEGLDIO_00823	5.76e-308	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MIEGLDIO_00824	9.35e-161	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MIEGLDIO_00825	1.25e-147	clpP1	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MIEGLDIO_00826	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
MIEGLDIO_00827	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MIEGLDIO_00828	0.0	rarA	-	-	L	ko:K07478	-	ko00000	Recombination factor protein RarA
MIEGLDIO_00829	0.0	-	-	-	L	-	-	-	DEAD DEAH box helicase
MIEGLDIO_00830	4.93e-244	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
MIEGLDIO_00831	4.31e-258	gluD	-	-	E	ko:K10007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_00832	1.04e-144	gluC	-	-	E	ko:K10006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_00833	1.25e-196	gluB	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MIEGLDIO_00834	4.49e-176	gluA	-	-	E	ko:K10008	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding protein of ABC transporter for glutamate K02028
MIEGLDIO_00835	1.01e-179	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MIEGLDIO_00836	0.0	glnP	-	-	E	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_00837	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MIEGLDIO_00838	0.0	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
MIEGLDIO_00839	1.25e-299	-	-	-	S	-	-	-	Domain of Unknown Function (DUF349)
MIEGLDIO_00840	5.73e-179	-	3.5.2.10	-	S	ko:K01470	ko00330,map00330	ko00000,ko00001,ko01000	Creatinine amidohydrolase
MIEGLDIO_00841	7.96e-316	proP	-	-	EGP	ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
MIEGLDIO_00842	0.0	-	-	-	QT	-	-	-	Purine catabolism regulatory protein-like family
MIEGLDIO_00843	0.0	codA	3.5.4.1, 3.5.4.21	-	F	ko:K01485,ko:K03365	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
MIEGLDIO_00844	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
MIEGLDIO_00845	1.36e-242	uspA	-	-	T	-	-	-	Belongs to the universal stress protein A family
MIEGLDIO_00846	1.23e-243	-	-	-	S	-	-	-	Protein of unknown function (DUF3027)
MIEGLDIO_00847	6.1e-88	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
MIEGLDIO_00848	0.0	phoR	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
MIEGLDIO_00849	2.04e-169	phoP	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulator receiver domain protein
MIEGLDIO_00850	8.75e-169	-	-	-	-	-	-	-	-
MIEGLDIO_00851	1.74e-38	-	-	-	S	-	-	-	Proteins of 100 residues with WXG
MIEGLDIO_00852	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MIEGLDIO_00853	1.2e-117	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
MIEGLDIO_00854	9.46e-176	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MIEGLDIO_00855	1.31e-233	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
MIEGLDIO_00856	1.49e-224	-	-	-	S	-	-	-	Protein of unknown function DUF58
MIEGLDIO_00857	1.91e-120	-	-	-	-	-	-	-	-
MIEGLDIO_00858	1.4e-239	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
MIEGLDIO_00859	7.17e-234	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
MIEGLDIO_00860	7.03e-104	-	-	-	-	-	-	-	-
MIEGLDIO_00861	0.0	-	-	-	S	-	-	-	PGAP1-like protein
MIEGLDIO_00862	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminal
MIEGLDIO_00863	0.0	-	-	-	S	-	-	-	Lysylphosphatidylglycerol synthase TM region
MIEGLDIO_00864	4.7e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
MIEGLDIO_00865	1.11e-77	-	-	-	-	-	-	-	-
MIEGLDIO_00866	7.66e-181	-	-	-	C	-	-	-	FMN binding
MIEGLDIO_00867	0.0	pafA	6.3.1.19	-	O	ko:K13571	-	ko00000,ko00002,ko01000,ko03051	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MIEGLDIO_00868	5.14e-34	pup	-	-	S	ko:K13570	-	ko00000,ko04121	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
MIEGLDIO_00869	8.18e-206	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
MIEGLDIO_00870	0.0	dop	3.5.1.119	-	S	ko:K20814	-	ko00000,ko01000,ko03051	Pup-ligase protein
MIEGLDIO_00871	0.0	arc	-	-	O	ko:K13527	ko03050,map03050	ko00000,ko00001,ko00002,ko03051	AAA ATPase forming ring-shaped complexes
MIEGLDIO_00872	1.29e-158	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
MIEGLDIO_00873	3.54e-229	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MIEGLDIO_00874	1.23e-172	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MIEGLDIO_00875	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MIEGLDIO_00876	2.13e-290	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MIEGLDIO_00877	5.45e-61	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MIEGLDIO_00878	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
MIEGLDIO_00880	8.88e-138	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MIEGLDIO_00881	1.42e-218	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MIEGLDIO_00882	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
MIEGLDIO_00883	2.95e-305	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
MIEGLDIO_00884	1.21e-98	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MIEGLDIO_00885	2.2e-134	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MIEGLDIO_00886	2.12e-295	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MIEGLDIO_00887	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MIEGLDIO_00888	9.4e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MIEGLDIO_00889	5.77e-81	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MIEGLDIO_00890	1.75e-179	-	-	-	S	ko:K03453	-	ko00000	SBF-like CPA transporter family (DUF4137)
MIEGLDIO_00891	2.86e-36	-	-	-	S	ko:K03453	-	ko00000	SBF-like CPA transporter family (DUF4137)
MIEGLDIO_00893	5.2e-253	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
MIEGLDIO_00894	1.53e-288	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
MIEGLDIO_00895	4.94e-288	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MIEGLDIO_00896	1.97e-175	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
MIEGLDIO_00897	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
MIEGLDIO_00898	1.79e-46	-	-	-	-	-	-	-	-
MIEGLDIO_00899	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	DNA-damage repair protein (DNA polymerase IV) K00961
MIEGLDIO_00900	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MIEGLDIO_00901	1.07e-242	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
MIEGLDIO_00902	4.17e-299	purD	6.3.3.1, 6.3.4.13	-	F	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
MIEGLDIO_00903	4.43e-150	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MIEGLDIO_00904	6.23e-128	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MIEGLDIO_00905	7.77e-234	rihB	3.2.2.1, 3.2.2.8	-	F	ko:K01239,ko:K01250,ko:K10213	ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
MIEGLDIO_00906	1.49e-273	-	-	-	C	ko:K19954	-	ko00000,ko01000	Iron-containing alcohol dehydrogenase
MIEGLDIO_00907	3.04e-165	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	N-(5'phosphoribosyl)anthranilate (PRA) isomerase
MIEGLDIO_00908	4.55e-242	yeiI	2.7.1.15, 2.7.1.45, 2.7.1.83	-	G	ko:K00852,ko:K00874,ko:K16328	ko00030,ko00240,ko01100,ko01120,ko01200,map00030,map00240,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
MIEGLDIO_00909	1.9e-258	-	2.7.1.83	-	G	ko:K16328	ko00240,map00240	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
MIEGLDIO_00910	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
MIEGLDIO_00911	1.28e-91	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
MIEGLDIO_00912	3.91e-285	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MIEGLDIO_00913	2.09e-110	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MIEGLDIO_00914	2.22e-232	yogA	-	-	C	-	-	-	Zinc-binding dehydrogenase
MIEGLDIO_00915	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MIEGLDIO_00916	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
MIEGLDIO_00917	3.77e-205	-	-	-	M	-	-	-	Conserved repeat domain
MIEGLDIO_00918	2.8e-172	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MIEGLDIO_00919	2.01e-98	-	-	-	-	-	-	-	-
MIEGLDIO_00920	2.8e-19	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
MIEGLDIO_00921	1.09e-177	hflK	-	-	O	-	-	-	prohibitin homologues
MIEGLDIO_00922	7.85e-59	-	-	-	O	-	-	-	Glutaredoxin
MIEGLDIO_00923	1.26e-41	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
MIEGLDIO_00924	4.33e-280	-	2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83	-	E	ko:K00812,ko:K08969,ko:K10206,ko:K14260,ko:K14261	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
MIEGLDIO_00925	3.58e-133	-	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 9.99
MIEGLDIO_00926	5.32e-243	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MIEGLDIO_00927	3.13e-197	metQ	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
MIEGLDIO_00928	2.98e-256	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MIEGLDIO_00929	4.83e-202	glnH	-	-	ET	ko:K02030,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MIEGLDIO_00930	4.1e-192	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATP binding protein of ABC transporter for glutamate aspartate K02028
MIEGLDIO_00931	3.03e-157	glnP	-	-	E	ko:K02029,ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_00932	4.59e-140	glnP2	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_00933	1.53e-147	-	-	-	K	-	-	-	acetyltransferase
MIEGLDIO_00937	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
MIEGLDIO_00939	3.78e-224	-	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
MIEGLDIO_00941	1.13e-273	-	-	-	P	-	-	-	Citrate transporter
MIEGLDIO_00942	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MIEGLDIO_00943	0.0	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MIEGLDIO_00944	0.0	aap1	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
MIEGLDIO_00945	9.24e-131	cysE	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MIEGLDIO_00946	1.29e-117	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MIEGLDIO_00947	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
MIEGLDIO_00948	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MIEGLDIO_00949	4.68e-280	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
MIEGLDIO_00950	2.45e-244	cbs	2.5.1.47, 4.2.1.22	-	E	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
MIEGLDIO_00951	1.46e-177	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
MIEGLDIO_00952	3.93e-176	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	oligopeptide transport protein of the ABC superfamily, ATP-binding component
MIEGLDIO_00953	5.4e-201	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_00954	8.06e-213	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_00955	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
MIEGLDIO_00956	3.97e-307	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MIEGLDIO_00957	8.08e-185	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MIEGLDIO_00958	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MIEGLDIO_00959	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
MIEGLDIO_00960	7.33e-289	sstT	-	-	E	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MIEGLDIO_00961	1.7e-185	-	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	RNA pseudouridylate synthase
MIEGLDIO_00962	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MIEGLDIO_00963	5.24e-187	tcyC	3.6.3.21	-	E	ko:K02028,ko:K02029	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MIEGLDIO_00964	3.25e-208	yecS	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_00965	1.87e-201	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
MIEGLDIO_00966	2.26e-53	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
MIEGLDIO_00967	2.49e-206	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
MIEGLDIO_00968	5e-106	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MIEGLDIO_00969	1.02e-226	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain protein
MIEGLDIO_00970	7.75e-206	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in cellular division
MIEGLDIO_00971	4.32e-241	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Cell division ATP-binding protein FtsE
MIEGLDIO_00972	2.95e-263	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MIEGLDIO_00973	5e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MIEGLDIO_00974	3.71e-215	dapD	2.3.1.117	-	E	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
MIEGLDIO_00975	0.0	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
MIEGLDIO_00976	5.71e-193	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
MIEGLDIO_00977	0.0	pepO	3.4.24.11, 3.4.24.71	-	O	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase family M13
MIEGLDIO_00978	3.6e-128	ssb2	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
MIEGLDIO_00979	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MIEGLDIO_00980	0.0	-	-	-	L	-	-	-	PIF1-like helicase
MIEGLDIO_00981	2.61e-210	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MIEGLDIO_00982	2.72e-156	orn	-	-	L	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MIEGLDIO_00983	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MIEGLDIO_00984	1.55e-254	rfe	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 4
MIEGLDIO_00985	2.44e-147	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
MIEGLDIO_00986	8.3e-160	livF	-	-	E	ko:K01995,ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
MIEGLDIO_00987	1.19e-192	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
MIEGLDIO_00988	3.76e-250	-	-	-	U	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MIEGLDIO_00989	8.89e-199	-	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MIEGLDIO_00990	6.78e-279	-	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
MIEGLDIO_00991	4.43e-221	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MIEGLDIO_00992	4.95e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MIEGLDIO_00993	2.63e-48	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
MIEGLDIO_00995	1.26e-287	xylR	-	-	GK	-	-	-	ROK family
MIEGLDIO_00996	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
MIEGLDIO_00997	2.08e-143	maa	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Bacterial transferase hexapeptide repeat protein
MIEGLDIO_00998	3.07e-11	-	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
MIEGLDIO_00999	0.0	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	Glycosyl hydrolase family 2, sugar binding domain protein
MIEGLDIO_01000	0.0	-	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
MIEGLDIO_01001	8.19e-212	-	-	-	P	ko:K02026,ko:K10119,ko:K17243	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_01002	1.98e-235	-	-	-	U	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_01003	3.75e-304	-	-	-	G	ko:K02027,ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter periplasmic binding protein YcjN precursor K02027
MIEGLDIO_01004	7.73e-233	-	-	-	K	ko:K02529,ko:K17640	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
MIEGLDIO_01005	0.0	-	3.2.1.37, 3.2.1.55	GH43,GH51	G	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
MIEGLDIO_01006	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
MIEGLDIO_01007	0.0	-	2.5.1.49	-	H	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.98
MIEGLDIO_01008	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
MIEGLDIO_01009	3.75e-81	-	-	-	S	ko:K07149	-	ko00000	Membrane
MIEGLDIO_01010	7.32e-45	-	-	-	S	ko:K07149	-	ko00000	Membrane
MIEGLDIO_01011	9.57e-22	-	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
MIEGLDIO_01012	1.6e-124	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MIEGLDIO_01014	1.49e-177	xylR	-	-	GK	-	-	-	ROK family
MIEGLDIO_01015	8.16e-22	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
MIEGLDIO_01016	1.98e-161	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
MIEGLDIO_01017	2.76e-215	-	-	-	F	-	-	-	Inosine-uridine preferring nucleoside hydrolase
MIEGLDIO_01018	1.47e-286	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
MIEGLDIO_01019	0.0	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	Glycosyl hydrolase family 2, sugar binding domain protein
MIEGLDIO_01021	8.12e-144	-	-	-	L	-	-	-	Integrase core domain
MIEGLDIO_01022	0.0	-	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolase family 10
MIEGLDIO_01023	1.66e-294	-	3.2.1.156	GH8	G	ko:K15531	-	ko00000,ko01000	CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
MIEGLDIO_01024	0.0	-	-	-	O	-	-	-	Highly conserved protein containing a thioredoxin domain
MIEGLDIO_01025	3e-193	-	-	-	L	-	-	-	PFAM Integrase catalytic
MIEGLDIO_01026	1.12e-132	-	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Cytidine and deoxycytidylate deaminase zinc-binding region
MIEGLDIO_01027	1.82e-97	fms	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
MIEGLDIO_01028	1.9e-231	-	-	-	V	-	-	-	Beta-lactamase
MIEGLDIO_01029	0.0	yjjK	-	-	S	-	-	-	ATP-binding cassette protein, ChvD family
MIEGLDIO_01030	3.77e-216	tesB	-	-	I	ko:K10805	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	Thioesterase-like superfamily
MIEGLDIO_01031	4.44e-123	-	-	-	S	-	-	-	Protein of unknown function (DUF3180)
MIEGLDIO_01032	0.0	folK	2.7.6.3, 4.1.2.25	-	H	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MIEGLDIO_01033	1.96e-196	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MIEGLDIO_01034	2.94e-149	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
MIEGLDIO_01035	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MIEGLDIO_01036	1.72e-128	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
MIEGLDIO_01037	1.14e-254	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MIEGLDIO_01038	1.85e-294	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-Ala-D-Ala carboxypeptidase 3 (S13) family
MIEGLDIO_01039	9.34e-294	-	-	-	M	-	-	-	Glycosyl transferase family 21
MIEGLDIO_01040	0.0	-	-	-	S	-	-	-	AI-2E family transporter
MIEGLDIO_01041	3.15e-230	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MIEGLDIO_01042	1.73e-270	fucO	1.1.1.77, 1.1.99.37, 1.2.98.1	-	C	ko:K00048,ko:K17067	ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
MIEGLDIO_01043	0.0	-	3.1.4.52	-	T	ko:K14051	ko02024,ko02026,map02024,map02026	ko00000,ko00001,ko01000	Putative diguanylate phosphodiesterase
MIEGLDIO_01044	4.21e-143	-	-	-	S	-	-	-	Domain of unknown function (DUF4956)
MIEGLDIO_01045	7.53e-201	-	-	-	P	-	-	-	VTC domain
MIEGLDIO_01046	0.0	-	-	-	M	ko:K06330	-	ko00000	CotH kinase protein
MIEGLDIO_01047	0.0	-	-	-	S	ko:K21012	ko02025,map02025	ko00000,ko00001	Putative exopolysaccharide Exporter (EPS-E)
MIEGLDIO_01048	0.0	-	-	GT4	M	ko:K21011	ko02025,map02025	ko00000,ko00001,ko01003	Domain of unknown function (DUF3492)
MIEGLDIO_01049	0.0	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2194)
MIEGLDIO_01050	2.15e-206	-	-	-	-	-	-	-	-
MIEGLDIO_01051	0.0	-	5.1.3.2	-	GM	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	ADP-glyceromanno-heptose 6-epimerase activity
MIEGLDIO_01055	6.26e-216	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MIEGLDIO_01056	3.01e-254	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MIEGLDIO_01058	1.79e-111	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	low molecular weight
MIEGLDIO_01059	2.33e-164	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dihydrofolate reductase
MIEGLDIO_01060	6.89e-232	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MIEGLDIO_01061	1.07e-94	-	-	-	O	-	-	-	OsmC-like protein
MIEGLDIO_01062	1.53e-242	-	-	-	T	-	-	-	Universal stress protein family
MIEGLDIO_01063	2.31e-121	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
MIEGLDIO_01064	6.95e-212	-	-	-	S	-	-	-	CHAP domain
MIEGLDIO_01065	5.66e-279	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MIEGLDIO_01066	3.36e-55	-	-	-	-	-	-	-	-
MIEGLDIO_01067	1.83e-274	senX3	2.7.13.3	-	T	ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
MIEGLDIO_01068	4.77e-130	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
MIEGLDIO_01069	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
MIEGLDIO_01070	2.86e-178	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MIEGLDIO_01071	1.76e-269	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
MIEGLDIO_01072	2.11e-125	-	-	-	S	ko:K06889	-	ko00000	Serine aminopeptidase, S33
MIEGLDIO_01073	0.0	-	-	-	G	ko:K03292	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
MIEGLDIO_01074	1.18e-244	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MIEGLDIO_01075	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
MIEGLDIO_01077	2.9e-275	-	-	-	EGP	ko:K08156,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
MIEGLDIO_01078	2.94e-207	-	-	-	S	-	-	-	Domain of unknown function (DUF4037)
MIEGLDIO_01079	3.95e-252	-	-	-	S	-	-	-	Domain of unknown function (DUF4037)
MIEGLDIO_01080	3.7e-149	-	-	-	S	-	-	-	Protein of unknown function (DUF4125)
MIEGLDIO_01081	6.69e-122	-	-	-	-	-	-	-	-
MIEGLDIO_01082	3.59e-195	pspC	-	-	KT	-	-	-	PspC domain
MIEGLDIO_01083	0.0	tcsS3	-	-	KT	-	-	-	PspC domain
MIEGLDIO_01084	1.68e-156	tcsR3	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MIEGLDIO_01085	1.96e-132	-	-	-	Q	-	-	-	Isochorismatase family
MIEGLDIO_01086	0.0	-	-	-	U	ko:K03457	-	ko00000	Permease for cytosine/purines, uracil, thiamine, allantoin
MIEGLDIO_01087	1.86e-242	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
MIEGLDIO_01088	1.68e-239	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
MIEGLDIO_01090	4.35e-312	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MIEGLDIO_01091	9.45e-261	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
MIEGLDIO_01092	3.7e-199	arbG	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
MIEGLDIO_01093	0.0	ptsG	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system, glucose-specific IIABC component
MIEGLDIO_01094	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
MIEGLDIO_01095	9.84e-194	-	-	-	T	-	-	-	LytTr DNA-binding domain
MIEGLDIO_01096	0.0	-	-	-	T	-	-	-	GHKL domain
MIEGLDIO_01097	6.27e-278	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MIEGLDIO_01098	3.43e-163	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MIEGLDIO_01099	5.05e-07	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
MIEGLDIO_01100	2.31e-140	-	-	-	-	-	-	-	-
MIEGLDIO_01101	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MIEGLDIO_01102	1.68e-276	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin kinase
MIEGLDIO_01103	2.03e-240	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MIEGLDIO_01104	1.9e-98	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MIEGLDIO_01105	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MIEGLDIO_01106	4.21e-243	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MIEGLDIO_01107	1.15e-113	-	-	-	-	-	-	-	-
MIEGLDIO_01109	2.62e-214	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MIEGLDIO_01110	1.21e-87	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MIEGLDIO_01111	6.43e-238	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MIEGLDIO_01112	1.48e-85	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MIEGLDIO_01113	6.96e-83	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MIEGLDIO_01114	1.47e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MIEGLDIO_01115	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MIEGLDIO_01116	1.05e-127	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MIEGLDIO_01117	5.9e-314	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MIEGLDIO_01118	7.28e-96	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
MIEGLDIO_01119	1.24e-35	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30p/L7e
MIEGLDIO_01120	5.14e-130	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MIEGLDIO_01121	1.86e-77	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MIEGLDIO_01122	5.66e-124	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MIEGLDIO_01123	3.93e-90	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MIEGLDIO_01124	4.1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MIEGLDIO_01125	1.6e-133	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MIEGLDIO_01126	1.81e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MIEGLDIO_01127	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MIEGLDIO_01128	5.52e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MIEGLDIO_01129	1.37e-50	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MIEGLDIO_01130	3.85e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MIEGLDIO_01131	2.74e-147	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MIEGLDIO_01132	5.42e-75	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MIEGLDIO_01133	3.44e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MIEGLDIO_01134	2.71e-195	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MIEGLDIO_01135	8.86e-62	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MIEGLDIO_01136	3.02e-151	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MIEGLDIO_01137	1.64e-151	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MIEGLDIO_01138	5.42e-67	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MIEGLDIO_01139	0.0	adhE	1.1.1.1, 1.2.1.10, 1.2.1.81	-	C	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
MIEGLDIO_01140	1.63e-231	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MIEGLDIO_01141	1.81e-251	-	1.1.1.9	-	C	ko:K05351	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
MIEGLDIO_01142	2.13e-305	csbX	-	-	EGP	-	-	-	Major Facilitator Superfamily
MIEGLDIO_01143	2.01e-275	-	-	-	GK	-	-	-	transcriptional repressor of nag (N-acetylglucosamine) operon K02565
MIEGLDIO_01144	2.55e-100	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MIEGLDIO_01145	0.0	glgX	3.2.1.196, 3.2.1.68	CBM48,GH13	G	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
MIEGLDIO_01146	1.21e-99	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MIEGLDIO_01147	4.42e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MIEGLDIO_01148	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
MIEGLDIO_01149	7.57e-152	-	-	-	-	-	-	-	-
MIEGLDIO_01150	1.63e-146	yigZ	-	-	S	-	-	-	Uncharacterized protein family UPF0029
MIEGLDIO_01151	1.35e-237	pdxB	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIEGLDIO_01152	0.0	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
MIEGLDIO_01153	1.07e-283	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MIEGLDIO_01155	0.0	-	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
MIEGLDIO_01156	0.0	-	-	-	G	-	-	-	candidate polyfunctional acetylxylan esterase b-xylosidase A-L-arabinofuranosidase, CBM9 module, glycoside hydrolase family 43 protein and carbohydrate esterase family 6 protein K01238
MIEGLDIO_01157	1.37e-299	-	3.2.1.156	GH8	G	ko:K15531	-	ko00000,ko01000	CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
MIEGLDIO_01158	0.0	-	-	-	G	-	-	-	Psort location Cytoplasmic, score 8.87
MIEGLDIO_01159	0.0	-	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
MIEGLDIO_01160	1.82e-195	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
MIEGLDIO_01161	8.75e-200	-	-	-	EP	ko:K02031,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
MIEGLDIO_01162	2.3e-179	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_01163	5.66e-231	-	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_01164	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
MIEGLDIO_01165	1.04e-267	dapC	-	-	E	-	-	-	Aminotransferase class I and II
MIEGLDIO_01166	2.61e-78	fdxA	-	-	C	ko:K05524	-	ko00000	4Fe-4S binding domain
MIEGLDIO_01167	0.0	-	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
MIEGLDIO_01168	5.4e-273	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
MIEGLDIO_01169	7.79e-35	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
MIEGLDIO_01173	3.49e-63	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MIEGLDIO_01174	1.2e-214	-	-	-	-	-	-	-	-
MIEGLDIO_01175	2.69e-156	rimJ	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MIEGLDIO_01176	4.12e-128	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
MIEGLDIO_01177	2.78e-41	-	-	-	S	-	-	-	Putative regulatory protein
MIEGLDIO_01178	3.71e-117	-	-	-	NO	-	-	-	SAF
MIEGLDIO_01179	2.9e-49	-	-	-	-	-	-	-	-
MIEGLDIO_01180	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
MIEGLDIO_01181	1.87e-232	-	-	-	T	-	-	-	Forkhead associated domain
MIEGLDIO_01182	5.66e-69	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MIEGLDIO_01183	5.91e-114	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MIEGLDIO_01184	9.45e-315	-	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
MIEGLDIO_01185	1.05e-182	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
MIEGLDIO_01186	6.41e-190	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MIEGLDIO_01187	1.11e-217	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
MIEGLDIO_01188	1.5e-208	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MIEGLDIO_01189	1.75e-255	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import
MIEGLDIO_01190	4.65e-166	regX3	-	-	KT	ko:K07776	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
MIEGLDIO_01191	3.39e-279	phoR	2.7.13.3	-	T	ko:K07636,ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
MIEGLDIO_01192	7.36e-159	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MIEGLDIO_01193	1.44e-281	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MIEGLDIO_01194	2.1e-268	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MIEGLDIO_01195	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MIEGLDIO_01196	7.66e-147	-	-	-	D	-	-	-	nuclear chromosome segregation
MIEGLDIO_01197	8.36e-162	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MIEGLDIO_01198	7.53e-185	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MIEGLDIO_01199	2.31e-234	yfiH	-	-	Q	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
MIEGLDIO_01200	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32 C-terminal domain
MIEGLDIO_01201	1.53e-217	-	-	-	C	-	-	-	Oxidoreductase, aldo keto reductase family protein
MIEGLDIO_01202	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
MIEGLDIO_01203	2.09e-118	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
MIEGLDIO_01204	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MIEGLDIO_01205	2.04e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MIEGLDIO_01206	1.33e-151	-	-	-	-	-	-	-	-
MIEGLDIO_01208	0.0	ams	2.4.1.4	GH13	G	ko:K05341	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
MIEGLDIO_01209	1.77e-107	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MIEGLDIO_01211	0.0	fas	-	-	I	ko:K11533	ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931	ko00000,ko00001,ko00002,ko01000,ko01004	Beta-ketoacyl synthase, C-terminal domain
MIEGLDIO_01212	0.0	pccB	-	-	I	-	-	-	Carboxyl transferase domain
MIEGLDIO_01213	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase L chain, ATP binding domain protein
MIEGLDIO_01214	4.65e-115	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
MIEGLDIO_01215	6.21e-207	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
MIEGLDIO_01216	0.0	-	-	-	-	-	-	-	-
MIEGLDIO_01217	1.14e-183	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
MIEGLDIO_01218	1.18e-157	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MIEGLDIO_01219	5.21e-95	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MIEGLDIO_01220	3.77e-176	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MIEGLDIO_01221	3.48e-44	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MIEGLDIO_01223	2.71e-295	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
MIEGLDIO_01224	3.06e-261	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MIEGLDIO_01225	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MIEGLDIO_01226	3.53e-52	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
MIEGLDIO_01227	1.19e-61	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MIEGLDIO_01228	0.0	rne	3.1.26.12	-	J	ko:K08300,ko:K08301	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	Ribonuclease E/G family
MIEGLDIO_01229	5.84e-294	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
MIEGLDIO_01230	3.73e-212	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
MIEGLDIO_01231	0.0	-	-	-	V	-	-	-	Efflux ABC transporter, permease protein
MIEGLDIO_01232	1.13e-165	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MIEGLDIO_01233	8.62e-165	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MIEGLDIO_01234	5.67e-151	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MIEGLDIO_01235	3.37e-79	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MIEGLDIO_01236	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MIEGLDIO_01237	7.15e-232	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
MIEGLDIO_01240	4.55e-226	-	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Psort location Cytoplasmic, score 8.87
MIEGLDIO_01241	1.74e-44	-	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Psort location Cytoplasmic, score 8.87
MIEGLDIO_01242	1.31e-303	-	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Psort location Cytoplasmic, score 8.87
MIEGLDIO_01243	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MIEGLDIO_01244	2.31e-180	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MIEGLDIO_01245	2.49e-156	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MIEGLDIO_01246	6.07e-102	-	-	-	K	-	-	-	MerR, DNA binding
MIEGLDIO_01247	6.86e-249	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
MIEGLDIO_01248	1.19e-75	-	-	-	S	-	-	-	Protein of unknown function (DUF3039)
MIEGLDIO_01249	6.03e-114	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MIEGLDIO_01250	1.72e-170	-	-	-	-	-	-	-	-
MIEGLDIO_01251	1.52e-149	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
MIEGLDIO_01252	8.1e-36	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MIEGLDIO_01253	8.48e-178	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MIEGLDIO_01254	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
MIEGLDIO_01255	1.54e-118	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
MIEGLDIO_01257	1.56e-121	-	-	-	-	-	-	-	-
MIEGLDIO_01258	0.0	yjjK	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter
MIEGLDIO_01259	2.81e-194	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase C26
MIEGLDIO_01260	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MIEGLDIO_01261	1.63e-122	-	-	-	-	-	-	-	-
MIEGLDIO_01263	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MIEGLDIO_01264	1.01e-231	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
MIEGLDIO_01265	7.94e-83	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MIEGLDIO_01266	5.05e-47	-	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
MIEGLDIO_01267	2.18e-138	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MIEGLDIO_01268	8.97e-192	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MIEGLDIO_01269	1.52e-136	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Conserved hypothetical protein 95
MIEGLDIO_01270	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	helicase superfamily c-terminal domain
MIEGLDIO_01271	1.82e-41	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
MIEGLDIO_01272	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MIEGLDIO_01273	2.11e-307	-	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
MIEGLDIO_01274	1.01e-165	gntR	-	-	K	-	-	-	FCD
MIEGLDIO_01275	2.8e-107	gntK	2.7.1.12	-	F	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Shikimate kinase
MIEGLDIO_01276	4.6e-293	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
MIEGLDIO_01277	1.35e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MIEGLDIO_01278	2.18e-289	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MIEGLDIO_01279	5.84e-293	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MIEGLDIO_01280	1.96e-177	-	-	-	M	-	-	-	Mechanosensitive ion channel
MIEGLDIO_01281	1.77e-225	-	-	-	S	-	-	-	CAAX protease self-immunity
MIEGLDIO_01282	1.28e-277	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MIEGLDIO_01283	1.31e-228	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
MIEGLDIO_01284	1.73e-225	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
MIEGLDIO_01285	0.0	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MIEGLDIO_01286	6.6e-259	pyr	1.3.98.1	-	F	ko:K00226	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
MIEGLDIO_01287	2.68e-169	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MIEGLDIO_01288	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MIEGLDIO_01289	1.9e-180	ltbR	-	-	K	-	-	-	Transcriptional regulator, IclR family, C-terminal domain protein
MIEGLDIO_01290	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MIEGLDIO_01293	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MIEGLDIO_01294	3.28e-189	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
MIEGLDIO_01295	1.07e-241	-	-	-	-	-	-	-	-
MIEGLDIO_01296	1.24e-158	-	-	-	G	-	-	-	Phosphoglycerate mutase family
MIEGLDIO_01297	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MIEGLDIO_01298	4.49e-125	-	-	-	S	-	-	-	GtrA-like protein
MIEGLDIO_01299	1.58e-81	-	-	-	S	-	-	-	Macrophage migration inhibitory factor (MIF)
MIEGLDIO_01300	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate-tetrahydrofolate ligase
MIEGLDIO_01301	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
MIEGLDIO_01302	5.02e-139	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
MIEGLDIO_01303	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MIEGLDIO_01304	1.53e-52	hpr	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
MIEGLDIO_01305	2.8e-234	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MIEGLDIO_01306	3.87e-247	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MIEGLDIO_01307	1.78e-137	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MIEGLDIO_01308	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MIEGLDIO_01309	5.96e-243	-	-	-	I	-	-	-	PAP2 superfamily
MIEGLDIO_01310	2.2e-298	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
MIEGLDIO_01311	1.28e-275	ino1	5.5.1.4	-	I	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	ko00000,ko00001,ko01000	Myo-inositol-1-phosphate synthase
MIEGLDIO_01312	0.0	pbp5	-	-	M	-	-	-	Transglycosylase
MIEGLDIO_01313	0.0	-	-	-	S	ko:K09955	-	ko00000	Beta-L-arabinofuranosidase, GH127
MIEGLDIO_01314	1.73e-195	-	-	-	U	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_01315	1.46e-214	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_01316	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MIEGLDIO_01317	8.04e-260	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
MIEGLDIO_01318	9.31e-251	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
MIEGLDIO_01319	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
MIEGLDIO_01320	0.0	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	C-terminal of Glycosyl hydrolases family 43
MIEGLDIO_01321	0.0	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	C-terminal of Glycosyl hydrolases family 43
MIEGLDIO_01322	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MIEGLDIO_01323	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MIEGLDIO_01324	8.81e-148	-	-	-	-	-	-	-	-
MIEGLDIO_01325	5.88e-15	-	-	-	T	-	-	-	Histidine kinase
MIEGLDIO_01326	1.61e-55	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MIEGLDIO_01327	9.7e-40	-	-	-	-	-	-	-	-
MIEGLDIO_01328	3.43e-88	-	-	-	-	-	-	-	-
MIEGLDIO_01329	1.41e-264	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MIEGLDIO_01330	1.17e-125	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
MIEGLDIO_01331	7.1e-175	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
MIEGLDIO_01332	1.84e-135	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MIEGLDIO_01333	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III subunit gamma tau
MIEGLDIO_01334	1.57e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MIEGLDIO_01335	6.51e-249	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
MIEGLDIO_01336	9.99e-273	-	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Diacylglycerol kinase catalytic domain protein
MIEGLDIO_01337	5.58e-72	-	-	-	S	-	-	-	TIGRFAM helicase secretion neighborhood TadE-like protein
MIEGLDIO_01338	2.1e-78	-	-	-	U	-	-	-	TadE-like protein
MIEGLDIO_01339	3.03e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF4244)
MIEGLDIO_01340	3.41e-116	-	-	-	NU	-	-	-	Type II secretion system (T2SS), protein F
MIEGLDIO_01341	5.96e-171	-	-	-	U	ko:K12510	-	ko00000,ko02044	Type ii secretion system
MIEGLDIO_01342	7.23e-238	cpaF	-	-	U	ko:K02283	-	ko00000,ko02035,ko02044	Type II IV secretion system protein
MIEGLDIO_01343	5.04e-181	-	-	-	D	-	-	-	bacterial-type flagellum organization
MIEGLDIO_01344	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MIEGLDIO_01345	1.08e-287	mutT	3.6.1.55	-	LT	ko:K03574	-	ko00000,ko01000,ko03400	Phosphoglycerate mutase family
MIEGLDIO_01346	3.33e-143	-	-	-	-	-	-	-	-
MIEGLDIO_01347	1.64e-151	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MIEGLDIO_01348	3.65e-260	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
MIEGLDIO_01349	0.0	-	-	-	G	-	-	-	Bacterial Ig-like domain (group 4)
MIEGLDIO_01350	0.0	-	3.2.1.187	GH121	DG	ko:K18206	-	ko00000,ko01000	Bacterial Ig-like domain (group 4)
MIEGLDIO_01351	0.0	-	3.2.1.185	GH127	S	ko:K09955,ko:K18205	-	ko00000,ko01000	Beta-L-arabinofuranosidase, GH127
MIEGLDIO_01352	3.39e-187	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_01353	5.95e-214	-	-	-	P	ko:K02025,ko:K10189	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_01355	5.38e-316	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MIEGLDIO_01356	2.65e-245	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein domain
MIEGLDIO_01357	0.0	-	-	-	S	ko:K03688	-	ko00000	ABC1 family
MIEGLDIO_01358	4.06e-42	-	-	-	S	-	-	-	granule-associated protein
MIEGLDIO_01359	1.33e-174	cobQ2	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
MIEGLDIO_01360	0.0	murE	-	-	M	-	-	-	Domain of unknown function (DUF1727)
MIEGLDIO_01361	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MIEGLDIO_01362	0.0	glnD	2.7.7.59	-	O	ko:K00990	ko02020,map02020	ko00000,ko00001,ko01000	Nucleotidyltransferase domain
MIEGLDIO_01363	8.92e-73	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Nitrogen regulatory protein P-II
MIEGLDIO_01364	2.92e-302	amt	-	-	U	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
MIEGLDIO_01365	5e-252	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MIEGLDIO_01366	2.69e-149	icaR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MIEGLDIO_01368	1.67e-250	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyltransferase like family 2
MIEGLDIO_01369	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
MIEGLDIO_01372	2.38e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
MIEGLDIO_01373	2.46e-288	-	-	-	S	-	-	-	Putative ABC-transporter type IV
MIEGLDIO_01374	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
MIEGLDIO_01375	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
MIEGLDIO_01376	1.06e-116	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
MIEGLDIO_01377	4.79e-103	-	-	-	S	-	-	-	FMN_bind
MIEGLDIO_01378	3.98e-191	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MIEGLDIO_01379	1.91e-267	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MIEGLDIO_01381	5.68e-286	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MIEGLDIO_01382	5.4e-292	-	-	-	S	-	-	-	Predicted membrane protein (DUF2318)
MIEGLDIO_01383	1.91e-133	-	-	-	P	ko:K07230	-	ko00000,ko02000	Fe2+ transport protein
MIEGLDIO_01384	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	Iron permease FTR1 family
MIEGLDIO_01385	3.31e-302	-	-	-	G	-	-	-	MFS/sugar transport protein
MIEGLDIO_01386	8.55e-148	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MIEGLDIO_01387	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
MIEGLDIO_01388	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MIEGLDIO_01389	3.21e-75	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MIEGLDIO_01390	4.56e-197	-	-	-	C	-	-	-	Aldo/keto reductase family
MIEGLDIO_01391	6.92e-37	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	ThiS family
MIEGLDIO_01392	5.02e-167	thiF	2.7.7.73	-	H	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
MIEGLDIO_01393	1.79e-214	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MIEGLDIO_01394	0.0	-	-	-	E	ko:K03293	-	ko00000	Amino acid permease
MIEGLDIO_01395	6.5e-115	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MIEGLDIO_01396	4.16e-263	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
MIEGLDIO_01397	0.0	-	-	-	M	-	-	-	domain protein
MIEGLDIO_01398	7.49e-234	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MIEGLDIO_01399	1.4e-100	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MIEGLDIO_01400	3.48e-310	-	-	-	P	-	-	-	Sodium/hydrogen exchanger family
MIEGLDIO_01401	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MIEGLDIO_01402	0.0	aroP	-	-	E	ko:K03293,ko:K11732	-	ko00000,ko02000	aromatic amino acid transport protein AroP K03293
MIEGLDIO_01403	4.27e-16	-	-	-	S	-	-	-	Protein of unknown function, DUF624
MIEGLDIO_01404	2.42e-239	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
MIEGLDIO_01405	2.65e-43	-	3.2.1.25	-	G	ko:K01192	ko00511,ko04142,map00511,map04142	ko00000,ko00001,ko01000	beta-mannosidase
MIEGLDIO_01406	0.0	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
MIEGLDIO_01407	5.04e-258	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MIEGLDIO_01408	2.65e-259	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MIEGLDIO_01409	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
MIEGLDIO_01410	0.0	scrT	-	-	G	-	-	-	Transporter major facilitator family protein
MIEGLDIO_01411	2.58e-193	-	-	-	P	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_01412	4.35e-210	-	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_01413	6.13e-296	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MIEGLDIO_01414	0.0	-	2.4.1.4, 3.2.1.1, 3.2.1.20, 5.4.99.16	GH13,GH31	G	ko:K01187,ko:K05341,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
MIEGLDIO_01415	7.71e-148	-	-	-	S	-	-	-	Protein of unknown function, DUF624
MIEGLDIO_01416	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Domain of unknown function (DUF1964)
MIEGLDIO_01417	5.58e-249	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MIEGLDIO_01418	2.41e-41	livK	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
MIEGLDIO_01419	5.18e-81	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MIEGLDIO_01420	2.89e-233	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MIEGLDIO_01421	8.19e-164	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
MIEGLDIO_01422	3.05e-136	-	-	-	L	-	-	-	Transposase and inactivated derivatives
MIEGLDIO_01423	9.59e-39	-	-	-	L	ko:K07483	-	ko00000	transposase activity
MIEGLDIO_01424	1.39e-195	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
MIEGLDIO_01425	9.01e-314	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MIEGLDIO_01426	2.85e-276	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
MIEGLDIO_01427	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
MIEGLDIO_01428	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
MIEGLDIO_01429	4.74e-217	-	-	-	EG	-	-	-	EamA-like transporter family
MIEGLDIO_01430	2.17e-88	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MIEGLDIO_01432	1.12e-210	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MIEGLDIO_01433	0.0	fprA	1.18.1.2, 1.19.1.1	-	C	ko:K00528	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase
MIEGLDIO_01434	5.52e-241	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
MIEGLDIO_01435	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
MIEGLDIO_01436	0.0	degP	-	-	O	ko:K08372	ko02020,map02020	ko00000,ko00001,ko01000,ko01002	Domain present in PSD-95, Dlg, and ZO-1/2.
MIEGLDIO_01437	0.0	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MIEGLDIO_01438	9.83e-29	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MIEGLDIO_01443	2.86e-09	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
MIEGLDIO_01444	1.84e-214	-	-	-	EG	-	-	-	EamA-like transporter family
MIEGLDIO_01445	3.44e-245	pldB	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Serine aminopeptidase, S33
MIEGLDIO_01446	6.6e-147	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MIEGLDIO_01447	1e-288	-	-	-	T	-	-	-	Histidine kinase
MIEGLDIO_01448	0.0	pepX	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Dipeptidyl peptidase IV (DPP IV) N-terminal region
MIEGLDIO_01449	2.6e-168	fhaA	-	-	T	-	-	-	Protein of unknown function (DUF2662)
MIEGLDIO_01450	1.57e-108	fhaB	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
MIEGLDIO_01451	0.0	pstP	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
MIEGLDIO_01452	0.0	rodA	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MIEGLDIO_01453	0.0	pbpA	-	-	M	ko:K05364	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
MIEGLDIO_01454	4.29e-227	pknA	2.7.11.1	-	T	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
MIEGLDIO_01455	0.0	pknB	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
MIEGLDIO_01456	3.3e-154	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	para-aminobenzoate synthase glutamine amidotransferase component II
MIEGLDIO_01457	1.36e-266	srtB	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MIEGLDIO_01458	1.12e-182	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
MIEGLDIO_01459	2.28e-90	crgA	-	-	D	-	-	-	Involved in cell division
MIEGLDIO_01460	2.83e-307	-	-	-	L	-	-	-	ribosomal rna small subunit methyltransferase
MIEGLDIO_01461	4.68e-190	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
MIEGLDIO_01462	3.8e-47	-	-	-	-	-	-	-	-
MIEGLDIO_01463	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MIEGLDIO_01464	6.39e-82	-	-	-	I	-	-	-	Sterol carrier protein
MIEGLDIO_01465	1.49e-64	-	-	-	S	-	-	-	Protein of unknown function (DUF3073)
MIEGLDIO_01466	2.64e-262	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MIEGLDIO_01467	0.0	-	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIEGLDIO_01468	0.0	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
MIEGLDIO_01469	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MIEGLDIO_01470	1.05e-47	-	-	-	-	-	-	-	-
MIEGLDIO_01471	1.67e-153	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
MIEGLDIO_01472	3.22e-304	-	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
MIEGLDIO_01473	2.82e-240	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
MIEGLDIO_01474	3.26e-103	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
MIEGLDIO_01478	2.21e-97	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MIEGLDIO_01479	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MIEGLDIO_01480	5.13e-106	-	-	-	S	-	-	-	Transmembrane domain of unknown function (DUF3566)
MIEGLDIO_01481	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MIEGLDIO_01482	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MIEGLDIO_01483	1.01e-115	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
MIEGLDIO_01484	1.35e-299	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MIEGLDIO_01485	1.09e-260	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MIEGLDIO_01486	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MIEGLDIO_01487	2.68e-19	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
MIEGLDIO_01488	2.26e-244	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
MIEGLDIO_01489	2.6e-118	jag	-	-	S	ko:K06346	-	ko00000	Putative single-stranded nucleic acids-binding domain
MIEGLDIO_01490	4.65e-168	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
MIEGLDIO_01491	3.04e-221	parA	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
MIEGLDIO_01492	1.49e-271	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MIEGLDIO_01493	6.95e-231	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MIEGLDIO_01494	1.6e-19	-	-	-	S	-	-	-	Psort location Extracellular, score 8.82
MIEGLDIO_01496	1.52e-155	-	-	-	S	-	-	-	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
MIEGLDIO_01497	6.29e-17	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
MIEGLDIO_01498	0.0	-	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
MIEGLDIO_01499	0.0	mviN	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
MIEGLDIO_01500	0.0	-	-	-	M	-	-	-	Conserved repeat domain
MIEGLDIO_01501	6.34e-156	mutT4	-	-	L	-	-	-	Belongs to the Nudix hydrolase family
MIEGLDIO_01502	0.0	pcnA	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Probable RNA and SrmB- binding site of polymerase A
MIEGLDIO_01503	8.42e-142	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
MIEGLDIO_01504	7.59e-215	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MIEGLDIO_01505	7.35e-221	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MIEGLDIO_01506	3.49e-253	rpfB	-	-	S	ko:K21688	-	ko00000	G5
MIEGLDIO_01508	1.33e-212	-	-	-	O	-	-	-	Thioredoxin
MIEGLDIO_01509	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
MIEGLDIO_01510	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
MIEGLDIO_01511	4.21e-42	yuxJ	-	-	EGP	-	-	-	Major facilitator Superfamily
MIEGLDIO_01512	6.82e-61	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MIEGLDIO_01513	1.7e-116	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MIEGLDIO_01515	1.08e-76	-	-	-	-	-	-	-	-
MIEGLDIO_01516	0.0	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
MIEGLDIO_01518	4.48e-106	-	-	-	-	-	-	-	-
MIEGLDIO_01519	0.0	-	-	-	S	ko:K07133	-	ko00000	AAA domain
MIEGLDIO_01520	1.43e-277	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
MIEGLDIO_01521	7.73e-298	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
MIEGLDIO_01522	1.67e-25	-	-	-	-	-	-	-	-
MIEGLDIO_01523	4.6e-101	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
MIEGLDIO_01524	7.12e-255	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MIEGLDIO_01525	0.0	rfbD	1.1.1.133, 5.1.3.13	-	M	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MIEGLDIO_01526	6.05e-196	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MIEGLDIO_01527	3.91e-32	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LICD family
MIEGLDIO_01528	1.7e-212	-	-	-	GM	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MIEGLDIO_01529	4.54e-143	tagG	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
MIEGLDIO_01530	5.75e-19	-	-	-	S	-	-	-	PFAM Glycosyl transferase family 2
MIEGLDIO_01531	4.6e-132	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	transferase activity, transferring glycosyl groups
MIEGLDIO_01532	5.61e-92	-	-	GT2	S	ko:K12992	ko02025,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyltransferase like family 2
MIEGLDIO_01533	7.72e-142	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MIEGLDIO_01534	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
MIEGLDIO_01535	2.33e-258	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MIEGLDIO_01536	3.86e-84	-	-	-	-	-	-	-	-
MIEGLDIO_01537	3.02e-253	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MIEGLDIO_01538	1.58e-215	iunH2	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
MIEGLDIO_01539	0.0	-	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
MIEGLDIO_01540	2.28e-223	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MIEGLDIO_01541	4.38e-243	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MIEGLDIO_01542	7.12e-62	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MIEGLDIO_01543	3.97e-107	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
MIEGLDIO_01544	3.05e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MIEGLDIO_01545	1.16e-92	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MIEGLDIO_01547	6.39e-177	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MIEGLDIO_01548	2.58e-113	-	-	-	M	-	-	-	Protein of unknown function (DUF3152)
MIEGLDIO_01549	5.43e-268	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MIEGLDIO_01550	2.82e-105	-	-	-	-	-	-	-	-
MIEGLDIO_01551	7.14e-190	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MIEGLDIO_01552	1.66e-210	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
MIEGLDIO_01553	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MIEGLDIO_01554	5.05e-184	-	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	Heavy metal translocating P-type atpase
MIEGLDIO_01555	2.8e-261	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
MIEGLDIO_01556	8.52e-135	pyrE1	-	-	F	-	-	-	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MIEGLDIO_01557	7.3e-168	trmH	2.1.1.34	-	J	ko:K00556	-	ko00000,ko01000,ko03016	RNA methyltransferase TrmH family
MIEGLDIO_01558	8.44e-167	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MIEGLDIO_01559	7.81e-62	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MIEGLDIO_01560	0.0	gatA	6.3.5.6, 6.3.5.7	-	F	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MIEGLDIO_01561	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MIEGLDIO_01562	1.4e-261	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MIEGLDIO_01563	1.43e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF2469)
MIEGLDIO_01564	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
MIEGLDIO_01565	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MIEGLDIO_01566	1.09e-104	lrp_3	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	helix_turn_helix ASNC type
MIEGLDIO_01567	6.95e-91	tyrA	5.4.99.5	-	E	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
MIEGLDIO_01568	0.0	-	-	-	S	-	-	-	domain protein
MIEGLDIO_01569	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MIEGLDIO_01570	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
MIEGLDIO_01571	9.55e-158	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MIEGLDIO_01572	1.1e-172	glnR	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
MIEGLDIO_01573	1.55e-173	-	-	-	-	-	-	-	-
MIEGLDIO_01574	1.22e-127	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MIEGLDIO_01575	2.28e-118	ppa	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MIEGLDIO_01576	0.0	glgE	2.4.99.16	GH13	G	ko:K16147	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
MIEGLDIO_01577	1.55e-223	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MIEGLDIO_01578	0.0	oxc	4.1.1.8	-	EH	ko:K01577	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Thiamine pyrophosphate enzyme, central domain
MIEGLDIO_01579	1.17e-247	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MIEGLDIO_01580	0.0	frc	2.8.3.15, 2.8.3.16	-	C	ko:K07544,ko:K07749	ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MIEGLDIO_01582	4.01e-263	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MIEGLDIO_01583	6.89e-190	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MIEGLDIO_01584	9.64e-42	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MIEGLDIO_01585	6.4e-93	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MIEGLDIO_01586	2.31e-191	atpH	-	-	C	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MIEGLDIO_01587	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MIEGLDIO_01588	5.5e-210	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MIEGLDIO_01589	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MIEGLDIO_01590	2.85e-60	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MIEGLDIO_01591	1.32e-156	nucS	-	-	L	ko:K07503	-	ko00000,ko01000	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
MIEGLDIO_01592	2.27e-192	-	5.2.1.8	-	M	ko:K01802	-	ko00000,ko01000	FKBP-type peptidyl-prolyl cis-trans isomerase
MIEGLDIO_01593	2.94e-264	-	-	-	-	-	-	-	-
MIEGLDIO_01594	1.98e-232	-	-	-	-	-	-	-	-
MIEGLDIO_01595	2.25e-217	ybbN	-	-	O	ko:K05838	-	ko00000,ko03110	Tetratricopeptide repeat
MIEGLDIO_01596	1.41e-156	-	-	-	S	-	-	-	CYTH
MIEGLDIO_01598	1.62e-83	psp1	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	Endoribonuclease L-PSP
MIEGLDIO_01599	0.0	-	-	-	E	ko:K16235	-	ko00000,ko02000	amino acid
MIEGLDIO_01600	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MIEGLDIO_01601	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MIEGLDIO_01602	3.73e-306	hom	1.1.1.3, 2.7.2.4	-	E	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
MIEGLDIO_01603	3.88e-240	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MIEGLDIO_01604	0.0	maf	-	-	DF	ko:K06287	-	ko00000	Maf-like protein
MIEGLDIO_01605	5.78e-268	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
MIEGLDIO_01606	0.0	araB	-	-	G	-	-	-	FGGY family of carbohydrate kinases, C-terminal domain
MIEGLDIO_01607	1.1e-167	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Class II Aldolase and Adducin N-terminal domain
MIEGLDIO_01608	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
MIEGLDIO_01609	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
MIEGLDIO_01610	0.0	-	-	-	V	ko:K06147,ko:K06148,ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter transmembrane region
MIEGLDIO_01611	6.62e-199	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MIEGLDIO_01612	8.19e-162	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MIEGLDIO_01613	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MIEGLDIO_01614	6.86e-204	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_01615	8.27e-213	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
MIEGLDIO_01616	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
MIEGLDIO_01617	2.39e-253	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
MIEGLDIO_01618	6.3e-308	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
MIEGLDIO_01619	1.21e-211	-	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
MIEGLDIO_01620	2.87e-154	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
MIEGLDIO_01621	4.82e-285	-	-	-	T	-	-	-	Diguanylate cyclase (GGDEF) domain protein
MIEGLDIO_01622	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
MIEGLDIO_01623	7.23e-63	-	-	-	-	-	-	-	-
MIEGLDIO_01624	2.22e-193	staP	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
MIEGLDIO_01625	1.08e-109	etp	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
MIEGLDIO_01626	1.89e-283	-	-	-	S	-	-	-	Protein of unknown function (DUF4012)
MIEGLDIO_01627	7.75e-256	wcoI	-	-	DM	-	-	-	Psort location CytoplasmicMembrane, score
MIEGLDIO_01628	3.16e-35	-	-	-	-	-	-	-	-
MIEGLDIO_01629	3.92e-141	-	-	-	-	-	-	-	-
MIEGLDIO_01630	1.2e-147	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
MIEGLDIO_01631	1.01e-47	etp	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
MIEGLDIO_01632	2.53e-66	etp	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
MIEGLDIO_01633	7.51e-139	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
MIEGLDIO_01635	1.67e-210	-	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	Domain of unknown function (DUF1972)
MIEGLDIO_01636	9.23e-216	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
MIEGLDIO_01637	4.94e-65	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
MIEGLDIO_01638	1.24e-34	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
MIEGLDIO_01639	2.24e-10	-	-	-	M	-	-	-	O-antigen ligase
MIEGLDIO_01640	2.16e-171	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
MIEGLDIO_01641	6.27e-147	-	-	-	C	-	-	-	Polysaccharide pyruvyl transferase
MIEGLDIO_01642	1.29e-55	-	-	-	S	-	-	-	Core-2/I-Branching enzyme
MIEGLDIO_01644	6.55e-251	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MIEGLDIO_01645	0.0	rfbD	1.1.1.133, 5.1.3.13	-	M	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MIEGLDIO_01646	7.03e-215	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MIEGLDIO_01647	0.0	-	-	-	-	-	-	-	-
MIEGLDIO_01650	7.39e-63	-	-	-	-	-	-	-	-
MIEGLDIO_01651	4.86e-89	-	-	-	S	-	-	-	KAP family P-loop domain
MIEGLDIO_01654	7.05e-109	-	-	-	K	-	-	-	SIR2-like domain
MIEGLDIO_01655	2.8e-15	-	-	-	-	-	-	-	-
MIEGLDIO_01656	3.03e-133	istB	-	-	L	-	-	-	IstB-like ATP binding protein
MIEGLDIO_01657	5.6e-195	-	-	-	L	-	-	-	PFAM Integrase catalytic
MIEGLDIO_01658	3.27e-13	-	-	-	L	-	-	-	Transposase, Mutator family
MIEGLDIO_01659	1.33e-37	tnp3503b	-	-	L	-	-	-	Transposase and inactivated derivatives
MIEGLDIO_01660	1.85e-85	-	-	-	-	-	-	-	-
MIEGLDIO_01661	1.44e-110	-	-	-	-	-	-	-	-
MIEGLDIO_01662	2.45e-44	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
MIEGLDIO_01663	6.07e-74	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
MIEGLDIO_01664	5.17e-74	yccF	-	-	S	-	-	-	Inner membrane component domain
MIEGLDIO_01665	1.15e-234	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MIEGLDIO_01666	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MIEGLDIO_01667	1.11e-208	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_01668	5.43e-189	-	-	-	P	ko:K02026,ko:K10190	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_01669	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
MIEGLDIO_01670	0.0	-	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
MIEGLDIO_01671	4.89e-09	wcoI	-	-	DM	-	-	-	Psort location CytoplasmicMembrane, score
MIEGLDIO_01672	4.23e-115	-	-	-	-	-	-	-	-
MIEGLDIO_01673	2.64e-221	-	-	-	S	ko:K21688	-	ko00000	G5
MIEGLDIO_01674	3.24e-77	trxA	1.8.1.9	-	O	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	ko00000,ko00001,ko01000,ko03110	Belongs to the thioredoxin family
MIEGLDIO_01675	2.77e-147	-	-	-	F	-	-	-	Domain of unknown function (DUF4916)
MIEGLDIO_01676	5.7e-200	-	-	-	I	-	-	-	Alpha/beta hydrolase family
MIEGLDIO_01677	4.2e-265	nudC	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
MIEGLDIO_01678	1.36e-91	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
MIEGLDIO_01679	1.07e-301	-	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2183)
MIEGLDIO_01680	0.0	ptrB	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Peptidase, S9A B C family, catalytic domain protein
MIEGLDIO_01681	7.9e-246	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MIEGLDIO_01682	1.32e-135	-	-	-	J	-	-	-	TM2 domain
MIEGLDIO_01683	5.21e-275	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
MIEGLDIO_01684	3.02e-170	crp	-	-	K	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
MIEGLDIO_01685	0.0	pon1	-	-	M	-	-	-	Transglycosylase
MIEGLDIO_01686	4.15e-280	namA	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
MIEGLDIO_01687	1.41e-289	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
MIEGLDIO_01688	1.13e-181	-	-	-	K	-	-	-	DeoR C terminal sensor domain
MIEGLDIO_01689	0.0	galT	2.7.7.12	-	C	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, N-terminal domain
MIEGLDIO_01690	1.19e-296	galK	2.7.1.6, 2.7.7.12	-	G	ko:K00849,ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
MIEGLDIO_01691	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MIEGLDIO_01692	3.67e-228	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_01693	5.56e-217	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_01694	1.01e-151	-	-	-	S	-	-	-	Protein of unknown function, DUF624
MIEGLDIO_01695	3.23e-249	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MIEGLDIO_01696	0.0	-	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
MIEGLDIO_01697	1.32e-57	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
MIEGLDIO_01698	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
MIEGLDIO_01699	6.41e-162	spoU	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MIEGLDIO_01700	1.21e-221	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	FES
MIEGLDIO_01701	3.56e-138	-	-	-	-	-	-	-	-
MIEGLDIO_01702	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MIEGLDIO_01703	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MIEGLDIO_01704	1.5e-111	-	-	-	T	-	-	-	Forkhead associated domain
MIEGLDIO_01705	2.07e-105	-	-	-	B	-	-	-	Belongs to the OprB family
MIEGLDIO_01706	0.0	-	-	-	E	-	-	-	Transglutaminase-like superfamily
MIEGLDIO_01707	2.31e-282	-	-	-	S	-	-	-	Protein of unknown function DUF58
MIEGLDIO_01708	2.69e-302	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
MIEGLDIO_01709	0.0	-	-	-	S	-	-	-	Fibronectin type 3 domain
MIEGLDIO_01710	0.0	pknK	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
MIEGLDIO_01711	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
MIEGLDIO_01712	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	Belongs to the helicase family. UvrD subfamily
MIEGLDIO_01713	1.15e-313	-	-	-	G	-	-	-	Major Facilitator Superfamily
MIEGLDIO_01714	4.54e-171	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MIEGLDIO_01715	6.79e-52	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
MIEGLDIO_01716	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
MIEGLDIO_01717	4.1e-223	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MIEGLDIO_01718	0.0	rnj	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MIEGLDIO_01719	0.0	pepN	3.4.11.2	-	E	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Peptidase family M1 domain
MIEGLDIO_01720	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MIEGLDIO_01721	3.3e-158	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MIEGLDIO_01722	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MIEGLDIO_01723	2.44e-05	-	-	-	-	-	-	-	-
MIEGLDIO_01724	7.45e-18	-	-	-	-	-	-	-	-
MIEGLDIO_01725	3.53e-57	-	-	-	-	-	-	-	-
MIEGLDIO_01726	2.69e-182	nfrA	-	-	C	-	-	-	Nitroreductase family
MIEGLDIO_01727	1.24e-81	-	-	-	S	-	-	-	Protein of unknown function (DUF4235)
MIEGLDIO_01728	8.44e-178	gpm2	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
MIEGLDIO_01729	0.0	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MIEGLDIO_01730	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
MIEGLDIO_01731	0.0	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MIEGLDIO_01732	3.58e-240	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
MIEGLDIO_01733	1.39e-234	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MIEGLDIO_01734	2.23e-198	msmF	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_01735	2.6e-195	-	-	-	G	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MIEGLDIO_01736	4.04e-136	-	-	-	S	-	-	-	Protein of unknown function, DUF624
MIEGLDIO_01737	3.22e-18	-	-	-	S	-	-	-	Transposon-encoded protein TnpV
MIEGLDIO_01738	1.16e-140	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Peptidase family S51
MIEGLDIO_01739	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
MIEGLDIO_01740	0.0	malL	2.4.1.4, 3.2.1.1, 3.2.1.20, 5.4.99.16	GH13,GH31	G	ko:K01187,ko:K05341,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
MIEGLDIO_01741	4.44e-291	malE	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MIEGLDIO_01743	0.0	malC	-	-	G	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_01744	7.53e-209	malG	-	-	G	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_01745	0.0	apuB	3.2.1.41, 3.2.1.68	CBM48,GH13	G	ko:K01200,ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
MIEGLDIO_01746	6.12e-186	-	-	-	S	ko:K07025	-	ko00000	HAD-hyrolase-like
MIEGLDIO_01747	3.02e-181	traX	-	-	S	-	-	-	TraX protein
MIEGLDIO_01748	4.07e-246	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MIEGLDIO_01750	0.0	-	-	-	M	-	-	-	cell wall anchor domain protein
MIEGLDIO_01751	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MIEGLDIO_01752	2.29e-246	-	-	-	M	-	-	-	Cna protein B-type domain
MIEGLDIO_01753	5.66e-200	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MIEGLDIO_01754	4.92e-182	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MIEGLDIO_01755	1.74e-152	strK	3.1.3.1, 3.1.3.39	-	P	ko:K01077,ko:K04342	ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
MIEGLDIO_01756	5.66e-187	-	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
MIEGLDIO_01757	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MIEGLDIO_01758	5.1e-100	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MIEGLDIO_01759	1.14e-232	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	DnaJ molecular chaperone homology domain
MIEGLDIO_01760	1.61e-146	hspR	-	-	K	ko:K13640	-	ko00000,ko03000	transcriptional regulator, MerR family
MIEGLDIO_01761	6.08e-63	-	-	-	-	-	-	-	-
MIEGLDIO_01762	1.69e-166	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
MIEGLDIO_01764	1.1e-161	dedA1	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
MIEGLDIO_01765	1.37e-22	-	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Glycosyl hydrolase family 26
MIEGLDIO_01766	1.04e-245	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MIEGLDIO_01767	7.95e-139	-	-	-	-	-	-	-	-
MIEGLDIO_01768	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MIEGLDIO_01769	0.0	lacZ3	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
MIEGLDIO_01771	1.99e-175	-	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP)
MIEGLDIO_01772	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
MIEGLDIO_01773	1.21e-314	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
MIEGLDIO_01774	2.71e-53	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
MIEGLDIO_01775	3.49e-270	-	-	-	GK	-	-	-	ROK family
MIEGLDIO_01776	6.67e-308	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MIEGLDIO_01777	1.55e-195	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_01778	1.13e-220	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
MIEGLDIO_01779	3.94e-221	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MIEGLDIO_01780	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
MIEGLDIO_01781	9.06e-191	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MIEGLDIO_01782	2.16e-292	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
MIEGLDIO_01783	1.98e-239	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
MIEGLDIO_01784	0.0	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
MIEGLDIO_01785	0.0	-	3.2.1.14	GH18	S	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Carbohydrate binding domain
MIEGLDIO_01786	0.0	-	-	-	M	-	-	-	probably involved in cell wall
MIEGLDIO_01787	6.84e-243	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
MIEGLDIO_01788	0.0	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MIEGLDIO_01789	4.05e-215	-	-	-	G	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_01790	7.99e-196	-	-	-	P	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_01791	4.62e-291	-	-	-	M	-	-	-	Protein of unknown function (DUF2961)
MIEGLDIO_01792	1.92e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MIEGLDIO_01794	7.33e-272	-	-	-	I	-	-	-	Hydrolase, alpha beta domain protein
MIEGLDIO_01795	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MIEGLDIO_01796	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MIEGLDIO_01797	2.77e-161	-	-	-	-	-	-	-	-
MIEGLDIO_01798	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
MIEGLDIO_01799	6.55e-291	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
MIEGLDIO_01800	6.54e-294	-	-	-	G	-	-	-	Alpha galactosidase A
MIEGLDIO_01801	0.0	-	-	-	G	-	-	-	Alpha-L-arabinofuranosidase C-terminus
MIEGLDIO_01802	1.98e-234	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
MIEGLDIO_01803	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
MIEGLDIO_01804	5.56e-213	-	-	-	S	-	-	-	Glutamine amidotransferase domain
MIEGLDIO_01805	6.41e-192	-	-	-	T	ko:K06950	-	ko00000	HD domain
MIEGLDIO_01806	3.11e-234	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MIEGLDIO_01807	4.62e-309	-	-	-	V	-	-	-	ABC transporter permease
MIEGLDIO_01808	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
MIEGLDIO_01809	1.22e-138	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
MIEGLDIO_01810	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
MIEGLDIO_01811	6.39e-295	-	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
MIEGLDIO_01812	5.79e-56	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
MIEGLDIO_01813	2.01e-17	-	-	-	S	-	-	-	Psort location Extracellular, score 8.82
MIEGLDIO_01814	1.57e-175	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
MIEGLDIO_01815	3.12e-304	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MIEGLDIO_01816	3.36e-271	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
MIEGLDIO_01817	3.56e-145	vex	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MIEGLDIO_01818	1e-103	ypeA	2.3.1.1	-	K	ko:K22477	ko00220,ko01210,ko01230,map00220,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
MIEGLDIO_01819	1.78e-149	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Psort location CytoplasmicMembrane, score
MIEGLDIO_01820	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
MIEGLDIO_01821	5.41e-127	-	-	-	S	-	-	-	GtrA-like protein
MIEGLDIO_01823	0.0	-	-	-	S	-	-	-	LPXTG-motif cell wall anchor domain protein
MIEGLDIO_01824	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MIEGLDIO_01825	1.24e-212	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MIEGLDIO_01826	7.87e-172	-	-	-	-	-	-	-	-
MIEGLDIO_01827	2.72e-63	-	-	-	S	ko:K07133	-	ko00000	Psort location Cytoplasmic, score
MIEGLDIO_01828	3.07e-276	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
MIEGLDIO_01829	4.28e-142	-	-	-	-	-	-	-	-
MIEGLDIO_01830	5.21e-315	-	-	-	T	-	-	-	GHKL domain
MIEGLDIO_01831	4.34e-169	-	-	-	K	-	-	-	LytTr DNA-binding domain
MIEGLDIO_01832	1.26e-268	ugpC	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MIEGLDIO_01833	0.0	-	-	-	KLT	-	-	-	Domain of unknown function (DUF4032)
MIEGLDIO_01834	1.48e-223	rlmB	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MIEGLDIO_01835	3.9e-294	-	-	-	EGP	-	-	-	Transmembrane secretion effector
MIEGLDIO_01836	6.49e-19	-	-	-	S	-	-	-	Psort location Extracellular, score 8.82
MIEGLDIO_01837	1.44e-72	-	-	-	DJ	ko:K06218	-	ko00000,ko02048	Addiction module toxin, RelE StbE family
MIEGLDIO_01838	1.31e-64	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
MIEGLDIO_01839	1.58e-191	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
MIEGLDIO_01840	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
MIEGLDIO_01841	0.0	pacL2	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
MIEGLDIO_01842	1.99e-109	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
MIEGLDIO_01843	3.49e-215	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MIEGLDIO_01844	1.62e-184	cobB2	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
MIEGLDIO_01845	1.76e-296	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
MIEGLDIO_01846	0.0	-	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
MIEGLDIO_01847	1.51e-198	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_01848	3.02e-205	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIEGLDIO_01849	8.66e-313	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MIEGLDIO_01850	5.18e-295	-	-	-	GK	-	-	-	ROK family
MIEGLDIO_01851	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
MIEGLDIO_01852	2.32e-100	tadA	3.5.4.1, 3.5.4.33	-	FJ	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MIEGLDIO_01853	0.0	nhaP	-	-	P	ko:K03316	-	ko00000	Sodium/hydrogen exchanger family
MIEGLDIO_01854	4.9e-198	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
MIEGLDIO_01855	2.99e-144	dcd	3.5.4.13	-	F	ko:K01494	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dCTP deaminase family
MIEGLDIO_01856	0.0	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
MIEGLDIO_01857	1.05e-65	-	-	-	KLT	-	-	-	Protein tyrosine kinase