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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
IOFHDDHG_00001	2.92e-17	-	-	-	-	-	-	-	-
IOFHDDHG_00002	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
IOFHDDHG_00003	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
IOFHDDHG_00004	1.62e-213	-	-	-	O	-	-	-	Thioredoxin
IOFHDDHG_00006	4.09e-254	rpfB	-	-	S	ko:K21688	-	ko00000	G5
IOFHDDHG_00007	8.58e-220	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IOFHDDHG_00008	4.39e-214	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IOFHDDHG_00009	8.42e-142	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
IOFHDDHG_00010	0.0	pcnA	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Probable RNA and SrmB- binding site of polymerase A
IOFHDDHG_00011	6.34e-156	mutT4	-	-	L	-	-	-	Belongs to the Nudix hydrolase family
IOFHDDHG_00012	0.0	-	-	-	M	-	-	-	Conserved repeat domain
IOFHDDHG_00013	0.0	mviN	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
IOFHDDHG_00014	0.0	-	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
IOFHDDHG_00015	6.29e-17	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
IOFHDDHG_00016	7.54e-156	-	-	-	S	-	-	-	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
IOFHDDHG_00018	1.6e-19	-	-	-	S	-	-	-	Psort location Extracellular, score 8.82
IOFHDDHG_00019	3.3e-229	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IOFHDDHG_00020	1.22e-270	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IOFHDDHG_00021	3.04e-221	parA	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
IOFHDDHG_00022	2.69e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
IOFHDDHG_00023	2.6e-118	jag	-	-	S	ko:K06346	-	ko00000	Putative single-stranded nucleic acids-binding domain
IOFHDDHG_00024	2.26e-244	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
IOFHDDHG_00025	2.68e-19	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
IOFHDDHG_00026	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IOFHDDHG_00027	1.09e-260	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IOFHDDHG_00028	1.35e-299	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IOFHDDHG_00029	1.01e-115	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
IOFHDDHG_00030	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IOFHDDHG_00031	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IOFHDDHG_00032	5.13e-106	-	-	-	S	-	-	-	Transmembrane domain of unknown function (DUF3566)
IOFHDDHG_00033	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
IOFHDDHG_00034	2.21e-97	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IOFHDDHG_00038	3.41e-142	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
IOFHDDHG_00039	6.63e-239	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
IOFHDDHG_00040	3.75e-303	-	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
IOFHDDHG_00041	1.67e-153	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
IOFHDDHG_00042	5e-231	-	-	-	-	-	-	-	-
IOFHDDHG_00043	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IOFHDDHG_00044	0.0	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
IOFHDDHG_00045	0.0	-	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IOFHDDHG_00046	7.56e-262	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IOFHDDHG_00047	6.07e-64	-	-	-	S	-	-	-	Protein of unknown function (DUF3073)
IOFHDDHG_00048	6.39e-82	-	-	-	I	-	-	-	Sterol carrier protein
IOFHDDHG_00049	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IOFHDDHG_00050	3.8e-47	-	-	-	-	-	-	-	-
IOFHDDHG_00051	5.02e-185	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
IOFHDDHG_00052	1.25e-303	-	-	-	L	-	-	-	ribosomal rna small subunit methyltransferase
IOFHDDHG_00053	2.28e-90	crgA	-	-	D	-	-	-	Involved in cell division
IOFHDDHG_00054	1.3e-181	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
IOFHDDHG_00055	1.58e-265	srtB	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
IOFHDDHG_00056	3.3e-154	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	para-aminobenzoate synthase glutamine amidotransferase component II
IOFHDDHG_00057	0.0	pknB	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
IOFHDDHG_00058	4.29e-227	pknA	2.7.11.1	-	T	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
IOFHDDHG_00059	0.0	pbpA	-	-	M	ko:K05364	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
IOFHDDHG_00060	0.0	rodA	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
IOFHDDHG_00061	0.0	pstP	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
IOFHDDHG_00062	1.57e-108	fhaB	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
IOFHDDHG_00063	2.6e-168	fhaA	-	-	T	-	-	-	Protein of unknown function (DUF2662)
IOFHDDHG_00064	0.0	pepX	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Dipeptidyl peptidase IV (DPP IV) N-terminal region
IOFHDDHG_00065	1.27e-291	-	-	-	T	-	-	-	Histidine kinase
IOFHDDHG_00066	6.6e-147	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
IOFHDDHG_00067	3.89e-245	pldB	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Serine aminopeptidase, S33
IOFHDDHG_00068	1.84e-214	-	-	-	EG	-	-	-	EamA-like transporter family
IOFHDDHG_00071	0.0	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IOFHDDHG_00072	0.0	degP	-	-	O	ko:K08372	ko02020,map02020	ko00000,ko00001,ko01000,ko01002	Domain present in PSD-95, Dlg, and ZO-1/2.
IOFHDDHG_00073	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
IOFHDDHG_00074	1.07e-238	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
IOFHDDHG_00075	0.0	fprA	1.18.1.2, 1.19.1.1	-	C	ko:K00528	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase
IOFHDDHG_00076	5.3e-209	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
IOFHDDHG_00078	5.39e-237	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IOFHDDHG_00079	1.42e-218	-	-	-	EG	-	-	-	EamA-like transporter family
IOFHDDHG_00080	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
IOFHDDHG_00081	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
IOFHDDHG_00082	2.14e-262	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
IOFHDDHG_00083	9.01e-314	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IOFHDDHG_00084	1.39e-195	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
IOFHDDHG_00085	9.59e-39	-	-	-	L	ko:K07483	-	ko00000	transposase activity
IOFHDDHG_00086	3.05e-136	-	-	-	L	-	-	-	Transposase and inactivated derivatives
IOFHDDHG_00087	8.19e-164	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
IOFHDDHG_00088	1.92e-236	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOFHDDHG_00089	5.18e-81	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOFHDDHG_00090	1.99e-40	livK	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
IOFHDDHG_00091	4.58e-248	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IOFHDDHG_00092	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Domain of unknown function (DUF1964)
IOFHDDHG_00093	1.56e-147	-	-	-	S	-	-	-	Protein of unknown function, DUF624
IOFHDDHG_00094	0.0	-	2.4.1.4, 3.2.1.1, 3.2.1.20, 5.4.99.16	GH13,GH31	G	ko:K01187,ko:K05341,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
IOFHDDHG_00095	6.4e-298	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOFHDDHG_00096	5.08e-209	-	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_00097	7.4e-193	-	-	-	P	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_00098	0.0	scrT	-	-	G	-	-	-	Transporter major facilitator family protein
IOFHDDHG_00099	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
IOFHDDHG_00100	2.65e-259	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IOFHDDHG_00101	3.55e-258	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IOFHDDHG_00102	0.0	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
IOFHDDHG_00103	2.35e-52	-	3.2.1.25	-	G	ko:K01192	ko00511,ko04142,map00511,map04142	ko00000,ko00001,ko01000	beta-mannosidase
IOFHDDHG_00104	3.59e-241	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
IOFHDDHG_00105	4.62e-15	-	-	-	S	-	-	-	Protein of unknown function, DUF624
IOFHDDHG_00106	0.0	aroP	-	-	E	ko:K03293,ko:K11732	-	ko00000,ko02000	aromatic amino acid transport protein AroP K03293
IOFHDDHG_00107	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IOFHDDHG_00108	1.16e-308	-	-	-	P	-	-	-	Sodium/hydrogen exchanger family
IOFHDDHG_00109	1.4e-100	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
IOFHDDHG_00110	3.71e-234	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
IOFHDDHG_00111	0.0	-	-	-	M	-	-	-	domain protein
IOFHDDHG_00112	8.15e-253	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
IOFHDDHG_00113	7.59e-114	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
IOFHDDHG_00114	0.0	-	-	-	E	ko:K03293	-	ko00000	Amino acid permease
IOFHDDHG_00115	1.79e-214	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
IOFHDDHG_00116	2.91e-166	thiF	2.7.7.73	-	H	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
IOFHDDHG_00117	6.92e-37	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	ThiS family
IOFHDDHG_00118	1.07e-195	-	-	-	C	-	-	-	Aldo/keto reductase family
IOFHDDHG_00119	3.21e-75	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IOFHDDHG_00120	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
IOFHDDHG_00121	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
IOFHDDHG_00122	1.35e-147	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IOFHDDHG_00123	3.31e-302	-	-	-	G	-	-	-	MFS/sugar transport protein
IOFHDDHG_00124	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	Iron permease FTR1 family
IOFHDDHG_00125	9.48e-134	-	-	-	P	ko:K07230	-	ko00000,ko02000	Fe2+ transport protein
IOFHDDHG_00126	5.4e-292	-	-	-	S	-	-	-	Predicted membrane protein (DUF2318)
IOFHDDHG_00127	1.4e-286	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
IOFHDDHG_00129	1.29e-265	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IOFHDDHG_00130	3.98e-191	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOFHDDHG_00131	4.79e-103	-	-	-	S	-	-	-	FMN_bind
IOFHDDHG_00132	2.62e-118	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
IOFHDDHG_00133	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
IOFHDDHG_00134	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
IOFHDDHG_00135	8.57e-289	-	-	-	S	-	-	-	Putative ABC-transporter type IV
IOFHDDHG_00136	2.38e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
IOFHDDHG_00137	4.05e-257	-	-	-	M	-	-	-	cell wall binding repeat
IOFHDDHG_00139	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
IOFHDDHG_00140	1.37e-249	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyltransferase like family 2
IOFHDDHG_00141	6.61e-148	icaR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOFHDDHG_00142	1.43e-251	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IOFHDDHG_00143	1.45e-302	amt	-	-	U	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
IOFHDDHG_00144	2.56e-72	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Nitrogen regulatory protein P-II
IOFHDDHG_00145	0.0	glnD	2.7.7.59	-	O	ko:K00990	ko02020,map02020	ko00000,ko00001,ko01000	Nucleotidyltransferase domain
IOFHDDHG_00146	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
IOFHDDHG_00147	0.0	murE	-	-	M	-	-	-	Domain of unknown function (DUF1727)
IOFHDDHG_00148	1.14e-175	cobQ2	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
IOFHDDHG_00149	4.06e-42	-	-	-	S	-	-	-	granule-associated protein
IOFHDDHG_00150	0.0	-	-	-	S	ko:K03688	-	ko00000	ABC1 family
IOFHDDHG_00151	9.24e-246	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein domain
IOFHDDHG_00152	5.38e-316	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOFHDDHG_00154	5.95e-214	-	-	-	P	ko:K02025,ko:K10189	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_00155	3.39e-187	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_00156	0.0	-	3.2.1.185	GH127	S	ko:K09955,ko:K18205	-	ko00000,ko01000	Beta-L-arabinofuranosidase, GH127
IOFHDDHG_00157	0.0	-	3.2.1.187	GH121	DG	ko:K18206	-	ko00000,ko01000	Bacterial Ig-like domain (group 4)
IOFHDDHG_00158	0.0	-	-	-	G	-	-	-	Bacterial Ig-like domain (group 4)
IOFHDDHG_00159	1.33e-262	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
IOFHDDHG_00160	1.64e-151	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IOFHDDHG_00161	8.12e-134	-	-	-	-	-	-	-	-
IOFHDDHG_00162	1.08e-287	mutT	3.6.1.55	-	LT	ko:K03574	-	ko00000,ko01000,ko03400	Phosphoglycerate mutase family
IOFHDDHG_00163	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IOFHDDHG_00165	6.13e-182	-	-	-	D	-	-	-	bacterial-type flagellum organization
IOFHDDHG_00166	1.46e-237	cpaF	-	-	U	ko:K02283	-	ko00000,ko02035,ko02044	Type II IV secretion system protein
IOFHDDHG_00167	1.35e-167	-	-	-	U	ko:K12510	-	ko00000,ko02044	Type ii secretion system
IOFHDDHG_00168	3.41e-116	-	-	-	NU	-	-	-	Type II secretion system (T2SS), protein F
IOFHDDHG_00169	7.15e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF4244)
IOFHDDHG_00170	1.8e-79	-	-	-	U	-	-	-	TadE-like protein
IOFHDDHG_00171	5.58e-72	-	-	-	S	-	-	-	TIGRFAM helicase secretion neighborhood TadE-like protein
IOFHDDHG_00172	3.81e-274	-	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Diacylglycerol kinase catalytic domain protein
IOFHDDHG_00173	1.31e-248	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IOFHDDHG_00174	1.57e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOFHDDHG_00175	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III subunit gamma tau
IOFHDDHG_00176	3.18e-136	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IOFHDDHG_00177	1.18e-173	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
IOFHDDHG_00178	1.17e-125	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
IOFHDDHG_00179	5.73e-264	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IOFHDDHG_00181	8.81e-148	-	-	-	-	-	-	-	-
IOFHDDHG_00182	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IOFHDDHG_00183	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IOFHDDHG_00184	0.0	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	C-terminal of Glycosyl hydrolases family 43
IOFHDDHG_00185	0.0	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	C-terminal of Glycosyl hydrolases family 43
IOFHDDHG_00186	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
IOFHDDHG_00187	5.38e-250	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
IOFHDDHG_00188	1.69e-261	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
IOFHDDHG_00189	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOFHDDHG_00190	2.08e-214	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_00191	1.24e-204	-	-	-	U	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_00192	0.0	-	-	-	S	ko:K09955	-	ko00000	Beta-L-arabinofuranosidase, GH127
IOFHDDHG_00193	0.0	pbp5	-	-	M	-	-	-	Transglycosylase
IOFHDDHG_00194	1.28e-275	ino1	5.5.1.4	-	I	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	ko00000,ko00001,ko01000	Myo-inositol-1-phosphate synthase
IOFHDDHG_00195	2.2e-298	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
IOFHDDHG_00196	1.29e-244	-	-	-	I	-	-	-	PAP2 superfamily
IOFHDDHG_00197	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IOFHDDHG_00198	1.78e-137	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IOFHDDHG_00199	9.51e-248	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IOFHDDHG_00200	6.89e-235	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IOFHDDHG_00201	1.53e-52	hpr	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
IOFHDDHG_00202	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IOFHDDHG_00203	5.02e-139	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
IOFHDDHG_00204	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
IOFHDDHG_00205	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate-tetrahydrofolate ligase
IOFHDDHG_00206	1.58e-81	-	-	-	S	-	-	-	Macrophage migration inhibitory factor (MIF)
IOFHDDHG_00207	1.29e-124	-	-	-	S	-	-	-	GtrA-like protein
IOFHDDHG_00208	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOFHDDHG_00209	1.24e-158	-	-	-	G	-	-	-	Phosphoglycerate mutase family
IOFHDDHG_00210	1.86e-242	-	-	-	-	-	-	-	-
IOFHDDHG_00211	2.05e-188	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
IOFHDDHG_00212	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IOFHDDHG_00215	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IOFHDDHG_00216	1.9e-180	ltbR	-	-	K	-	-	-	Transcriptional regulator, IclR family, C-terminal domain protein
IOFHDDHG_00217	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IOFHDDHG_00218	2.68e-169	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IOFHDDHG_00219	1.33e-258	pyr	1.3.98.1	-	F	ko:K00226	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
IOFHDDHG_00220	0.0	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IOFHDDHG_00221	7.29e-224	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
IOFHDDHG_00222	1.31e-228	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
IOFHDDHG_00223	4.48e-278	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
IOFHDDHG_00224	1.77e-225	-	-	-	S	-	-	-	CAAX protease self-immunity
IOFHDDHG_00225	1.96e-177	-	-	-	M	-	-	-	Mechanosensitive ion channel
IOFHDDHG_00226	5.84e-293	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
IOFHDDHG_00227	2.18e-289	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
IOFHDDHG_00228	1.35e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOFHDDHG_00229	1.13e-293	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
IOFHDDHG_00230	1.66e-211	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase, C-terminal domain
IOFHDDHG_00231	5.57e-290	gnuT	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
IOFHDDHG_00232	2.8e-107	gntK	2.7.1.12	-	F	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Shikimate kinase
IOFHDDHG_00233	1.01e-165	gntR	-	-	K	-	-	-	FCD
IOFHDDHG_00234	2.11e-307	-	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
IOFHDDHG_00235	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
IOFHDDHG_00236	1.82e-41	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
IOFHDDHG_00237	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	helicase superfamily c-terminal domain
IOFHDDHG_00238	1.52e-136	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Conserved hypothetical protein 95
IOFHDDHG_00239	8.97e-192	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
IOFHDDHG_00240	1.81e-138	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IOFHDDHG_00241	5.05e-47	-	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
IOFHDDHG_00242	7.94e-83	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
IOFHDDHG_00243	1.01e-231	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
IOFHDDHG_00244	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IOFHDDHG_00245	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IOFHDDHG_00246	4.66e-193	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase C26
IOFHDDHG_00247	0.0	yjjK	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter
IOFHDDHG_00248	8.37e-126	-	-	-	-	-	-	-	-
IOFHDDHG_00250	1.54e-118	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
IOFHDDHG_00251	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
IOFHDDHG_00252	2.43e-177	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IOFHDDHG_00253	8.1e-36	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
IOFHDDHG_00254	4.89e-146	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
IOFHDDHG_00255	7.01e-170	-	-	-	-	-	-	-	-
IOFHDDHG_00256	6.03e-114	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IOFHDDHG_00257	1.02e-76	-	-	-	S	-	-	-	Protein of unknown function (DUF3039)
IOFHDDHG_00258	6.86e-249	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
IOFHDDHG_00259	2.47e-101	-	-	-	K	-	-	-	MerR, DNA binding
IOFHDDHG_00260	2.49e-156	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IOFHDDHG_00261	1.38e-177	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IOFHDDHG_00262	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IOFHDDHG_00263	1.04e-309	-	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Psort location Cytoplasmic, score 8.87
IOFHDDHG_00264	1.71e-300	-	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Psort location Cytoplasmic, score 8.87
IOFHDDHG_00267	7.15e-232	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
IOFHDDHG_00268	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
IOFHDDHG_00269	3.37e-79	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IOFHDDHG_00270	1.4e-158	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IOFHDDHG_00271	2.21e-176	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IOFHDDHG_00272	3.25e-165	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOFHDDHG_00273	0.0	-	-	-	V	-	-	-	Efflux ABC transporter, permease protein
IOFHDDHG_00274	3.73e-212	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
IOFHDDHG_00275	1.32e-290	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
IOFHDDHG_00276	0.0	rne	3.1.26.12	-	J	ko:K08300,ko:K08301	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	Ribonuclease E/G family
IOFHDDHG_00277	1.19e-61	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
IOFHDDHG_00278	3.53e-52	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
IOFHDDHG_00279	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IOFHDDHG_00280	3.06e-261	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IOFHDDHG_00281	1.06e-292	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
IOFHDDHG_00283	3.48e-44	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IOFHDDHG_00284	2.65e-176	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
IOFHDDHG_00285	5.21e-95	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IOFHDDHG_00286	1.18e-157	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IOFHDDHG_00287	4.85e-185	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
IOFHDDHG_00288	0.0	-	-	-	-	-	-	-	-
IOFHDDHG_00289	6.21e-207	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
IOFHDDHG_00290	9.8e-117	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
IOFHDDHG_00291	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase L chain, ATP binding domain protein
IOFHDDHG_00292	0.0	pccB	-	-	I	-	-	-	Carboxyl transferase domain
IOFHDDHG_00293	0.0	fas	-	-	I	ko:K11533	ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931	ko00000,ko00001,ko00002,ko01000,ko01004	Beta-ketoacyl synthase, C-terminal domain
IOFHDDHG_00295	1.77e-107	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IOFHDDHG_00296	0.0	ams	2.4.1.4	GH13	G	ko:K05341	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
IOFHDDHG_00298	1.89e-151	-	-	-	-	-	-	-	-
IOFHDDHG_00299	2.04e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IOFHDDHG_00300	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IOFHDDHG_00301	2.09e-118	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
IOFHDDHG_00302	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
IOFHDDHG_00303	4.37e-217	-	-	-	C	-	-	-	Oxidoreductase, aldo keto reductase family protein
IOFHDDHG_00304	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32 C-terminal domain
IOFHDDHG_00305	2.31e-234	yfiH	-	-	Q	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
IOFHDDHG_00306	7.53e-185	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
IOFHDDHG_00307	8.36e-162	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IOFHDDHG_00308	7.66e-147	-	-	-	D	-	-	-	nuclear chromosome segregation
IOFHDDHG_00309	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
IOFHDDHG_00310	2.1e-268	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IOFHDDHG_00311	1.44e-281	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IOFHDDHG_00312	1.73e-157	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IOFHDDHG_00313	1.38e-278	phoR	2.7.13.3	-	T	ko:K07636,ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
IOFHDDHG_00314	2.31e-166	regX3	-	-	KT	ko:K07776	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
IOFHDDHG_00315	3.02e-256	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import
IOFHDDHG_00316	1.5e-208	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
IOFHDDHG_00317	1.92e-218	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
IOFHDDHG_00318	6.41e-190	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IOFHDDHG_00319	1.28e-183	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
IOFHDDHG_00320	9.45e-315	-	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
IOFHDDHG_00321	5.91e-114	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IOFHDDHG_00322	5.66e-69	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IOFHDDHG_00323	1.87e-232	-	-	-	T	-	-	-	Forkhead associated domain
IOFHDDHG_00324	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
IOFHDDHG_00325	2.8e-47	-	-	-	-	-	-	-	-
IOFHDDHG_00326	3.71e-117	-	-	-	NO	-	-	-	SAF
IOFHDDHG_00327	1.14e-40	-	-	-	S	-	-	-	Putative regulatory protein
IOFHDDHG_00328	5.99e-129	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
IOFHDDHG_00329	8.74e-96	rimJ	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
IOFHDDHG_00330	2.09e-215	-	-	-	-	-	-	-	-
IOFHDDHG_00331	3.49e-63	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IOFHDDHG_00335	7.79e-35	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
IOFHDDHG_00336	1.48e-270	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
IOFHDDHG_00337	0.0	-	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
IOFHDDHG_00338	2.61e-78	fdxA	-	-	C	ko:K05524	-	ko00000	4Fe-4S binding domain
IOFHDDHG_00339	4.8e-273	dapC	-	-	E	-	-	-	Aminotransferase class I and II
IOFHDDHG_00341	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
IOFHDDHG_00342	2.8e-231	-	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_00343	3.26e-179	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_00344	1.45e-198	-	-	-	EP	ko:K02031,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
IOFHDDHG_00345	1.05e-194	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOFHDDHG_00346	0.0	-	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
IOFHDDHG_00347	0.0	-	-	-	G	-	-	-	Psort location Cytoplasmic, score 8.87
IOFHDDHG_00348	1.37e-299	-	3.2.1.156	GH8	G	ko:K15531	-	ko00000,ko01000	CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
IOFHDDHG_00349	0.0	-	-	-	G	-	-	-	candidate polyfunctional acetylxylan esterase b-xylosidase A-L-arabinofuranosidase, CBM9 module, glycoside hydrolase family 43 protein and carbohydrate esterase family 6 protein K01238
IOFHDDHG_00350	0.0	-	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
IOFHDDHG_00352	3.05e-283	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IOFHDDHG_00353	0.0	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
IOFHDDHG_00354	7.8e-237	pdxB	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOFHDDHG_00355	1.63e-146	yigZ	-	-	S	-	-	-	Uncharacterized protein family UPF0029
IOFHDDHG_00356	4.26e-158	-	-	-	-	-	-	-	-
IOFHDDHG_00357	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
IOFHDDHG_00358	2.26e-104	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IOFHDDHG_00359	1.21e-99	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
IOFHDDHG_00360	0.0	glgX	3.2.1.196, 3.2.1.68	CBM48,GH13	G	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
IOFHDDHG_00361	2.55e-100	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOFHDDHG_00362	3.73e-271	-	-	-	GK	-	-	-	transcriptional repressor of nag (N-acetylglucosamine) operon K02565
IOFHDDHG_00363	7.11e-304	csbX	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOFHDDHG_00364	2.11e-250	-	1.1.1.9	-	C	ko:K05351	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
IOFHDDHG_00365	3.42e-233	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IOFHDDHG_00366	0.0	adhE	1.1.1.1, 1.2.1.10, 1.2.1.81	-	C	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
IOFHDDHG_00367	5.42e-67	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
IOFHDDHG_00368	1.64e-151	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IOFHDDHG_00369	3.02e-151	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
IOFHDDHG_00370	8.86e-62	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IOFHDDHG_00371	2.71e-195	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IOFHDDHG_00372	3.44e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IOFHDDHG_00373	5.42e-75	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IOFHDDHG_00374	2.74e-147	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IOFHDDHG_00375	3.85e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IOFHDDHG_00376	1.37e-50	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
IOFHDDHG_00377	5.52e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IOFHDDHG_00378	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IOFHDDHG_00379	1.81e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IOFHDDHG_00380	1.6e-133	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IOFHDDHG_00381	4.1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IOFHDDHG_00382	8.55e-89	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IOFHDDHG_00383	5.66e-124	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IOFHDDHG_00384	1.86e-77	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IOFHDDHG_00385	5.14e-130	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IOFHDDHG_00386	1.24e-35	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30p/L7e
IOFHDDHG_00387	4.21e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
IOFHDDHG_00388	5.9e-314	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IOFHDDHG_00389	1.05e-127	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IOFHDDHG_00390	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IOFHDDHG_00391	1.47e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
IOFHDDHG_00392	6.96e-83	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IOFHDDHG_00393	1.48e-85	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IOFHDDHG_00394	6.43e-238	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOFHDDHG_00395	1.21e-87	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
IOFHDDHG_00396	1.91e-234	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IOFHDDHG_00398	3.63e-141	-	-	-	-	-	-	-	-
IOFHDDHG_00399	4.21e-243	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
IOFHDDHG_00400	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IOFHDDHG_00401	1.9e-98	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IOFHDDHG_00402	3.51e-241	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IOFHDDHG_00403	1.68e-276	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin kinase
IOFHDDHG_00404	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IOFHDDHG_00405	5.44e-139	-	-	-	-	-	-	-	-
IOFHDDHG_00406	5.05e-07	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
IOFHDDHG_00407	3.43e-163	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IOFHDDHG_00408	1.54e-278	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IOFHDDHG_00409	1.39e-254	-	-	-	T	-	-	-	GHKL domain
IOFHDDHG_00410	5.08e-196	-	-	-	T	-	-	-	LytTr DNA-binding domain
IOFHDDHG_00411	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
IOFHDDHG_00412	0.0	ptsG	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system, glucose-specific IIABC component
IOFHDDHG_00413	4.5e-200	arbG	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
IOFHDDHG_00414	9.45e-261	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
IOFHDDHG_00415	4.35e-312	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IOFHDDHG_00417	1.68e-239	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
IOFHDDHG_00418	1.86e-242	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
IOFHDDHG_00419	0.0	-	-	-	U	ko:K03457	-	ko00000	Permease for cytosine/purines, uracil, thiamine, allantoin
IOFHDDHG_00420	6.83e-133	-	-	-	Q	-	-	-	Isochorismatase family
IOFHDDHG_00421	4.82e-156	tcsR3	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
IOFHDDHG_00422	0.0	tcsS3	-	-	KT	-	-	-	PspC domain
IOFHDDHG_00423	1.17e-198	pspC	-	-	KT	-	-	-	PspC domain
IOFHDDHG_00424	5.5e-121	-	-	-	-	-	-	-	-
IOFHDDHG_00425	2.6e-149	-	-	-	S	-	-	-	Protein of unknown function (DUF4125)
IOFHDDHG_00426	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4037)
IOFHDDHG_00427	1.68e-274	-	-	-	EGP	ko:K08156,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
IOFHDDHG_00429	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
IOFHDDHG_00430	1.03e-264	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
IOFHDDHG_00431	2.86e-178	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IOFHDDHG_00432	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
IOFHDDHG_00433	8.62e-133	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
IOFHDDHG_00434	1.29e-274	senX3	2.7.13.3	-	T	ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
IOFHDDHG_00435	3.36e-55	-	-	-	-	-	-	-	-
IOFHDDHG_00436	5.66e-279	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IOFHDDHG_00437	9.87e-212	-	-	-	S	-	-	-	CHAP domain
IOFHDDHG_00438	2.31e-121	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
IOFHDDHG_00439	1.46e-240	-	-	-	T	-	-	-	Universal stress protein family
IOFHDDHG_00440	1.07e-94	-	-	-	O	-	-	-	OsmC-like protein
IOFHDDHG_00441	2.4e-232	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IOFHDDHG_00442	9.87e-166	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dihydrofolate reductase
IOFHDDHG_00443	1.79e-111	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	low molecular weight
IOFHDDHG_00445	3.01e-254	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
IOFHDDHG_00446	1.54e-216	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IOFHDDHG_00450	0.0	-	5.1.3.2	-	GM	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	ADP-glyceromanno-heptose 6-epimerase activity
IOFHDDHG_00451	1.72e-212	-	-	-	-	-	-	-	-
IOFHDDHG_00452	0.0	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2194)
IOFHDDHG_00453	0.0	-	-	GT4	M	ko:K21011	ko02025,map02025	ko00000,ko00001,ko01003	Domain of unknown function (DUF3492)
IOFHDDHG_00454	0.0	-	-	-	S	ko:K21012	ko02025,map02025	ko00000,ko00001	Putative exopolysaccharide Exporter (EPS-E)
IOFHDDHG_00455	0.0	-	-	-	M	ko:K06330	-	ko00000	CotH kinase protein
IOFHDDHG_00456	1.58e-202	-	-	-	P	-	-	-	VTC domain
IOFHDDHG_00457	2.54e-144	-	-	-	S	-	-	-	Domain of unknown function (DUF4956)
IOFHDDHG_00458	0.0	-	3.1.4.52	-	T	ko:K14051	ko02024,ko02026,map02024,map02026	ko00000,ko00001,ko01000	Putative diguanylate phosphodiesterase
IOFHDDHG_00459	1.73e-270	fucO	1.1.1.77, 1.1.99.37, 1.2.98.1	-	C	ko:K00048,ko:K17067	ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
IOFHDDHG_00460	3.15e-230	-	-	-	M	-	-	-	Glycosyltransferase like family 2
IOFHDDHG_00461	0.0	-	-	-	S	-	-	-	AI-2E family transporter
IOFHDDHG_00462	9.34e-294	-	-	-	M	-	-	-	Glycosyl transferase family 21
IOFHDDHG_00463	1.07e-293	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-Ala-D-Ala carboxypeptidase 3 (S13) family
IOFHDDHG_00464	1.14e-254	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IOFHDDHG_00465	1.72e-128	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
IOFHDDHG_00466	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IOFHDDHG_00467	2.51e-150	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
IOFHDDHG_00468	1.96e-196	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IOFHDDHG_00469	0.0	folK	2.7.6.3, 4.1.2.25	-	H	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IOFHDDHG_00470	5.18e-122	-	-	-	S	-	-	-	Protein of unknown function (DUF3180)
IOFHDDHG_00471	6.48e-211	tesB	-	-	I	ko:K10805	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	Thioesterase-like superfamily
IOFHDDHG_00472	0.0	yjjK	-	-	S	-	-	-	ATP-binding cassette protein, ChvD family
IOFHDDHG_00473	5.61e-56	-	-	-	V	-	-	-	Beta-lactamase
IOFHDDHG_00474	1.82e-97	fms	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
IOFHDDHG_00475	1.12e-132	-	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Cytidine and deoxycytidylate deaminase zinc-binding region
IOFHDDHG_00476	3e-193	-	-	-	L	-	-	-	PFAM Integrase catalytic
IOFHDDHG_00477	0.0	-	-	-	O	-	-	-	Highly conserved protein containing a thioredoxin domain
IOFHDDHG_00478	1.66e-294	-	3.2.1.156	GH8	G	ko:K15531	-	ko00000,ko01000	CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
IOFHDDHG_00479	0.0	-	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolase family 10
IOFHDDHG_00480	8.12e-144	-	-	-	L	-	-	-	Integrase core domain
IOFHDDHG_00482	0.0	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	Glycosyl hydrolase family 2, sugar binding domain protein
IOFHDDHG_00483	1.47e-286	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
IOFHDDHG_00484	2.76e-215	-	-	-	F	-	-	-	Inosine-uridine preferring nucleoside hydrolase
IOFHDDHG_00485	1.98e-161	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
IOFHDDHG_00486	8.16e-22	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
IOFHDDHG_00487	8.59e-177	xylR	-	-	GK	-	-	-	ROK family
IOFHDDHG_00489	1.6e-124	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
IOFHDDHG_00490	9.57e-22	-	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
IOFHDDHG_00491	7.32e-45	-	-	-	S	ko:K07149	-	ko00000	Membrane
IOFHDDHG_00492	3.75e-81	-	-	-	S	ko:K07149	-	ko00000	Membrane
IOFHDDHG_00493	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
IOFHDDHG_00494	0.0	-	2.5.1.49	-	H	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.98
IOFHDDHG_00495	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
IOFHDDHG_00496	0.0	-	3.2.1.37, 3.2.1.55	GH43,GH51	G	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
IOFHDDHG_00497	4.47e-232	-	-	-	K	ko:K02529,ko:K17640	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
IOFHDDHG_00498	3.75e-304	-	-	-	G	ko:K02027,ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter periplasmic binding protein YcjN precursor K02027
IOFHDDHG_00499	1.98e-235	-	-	-	U	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_00500	8.19e-212	-	-	-	P	ko:K02026,ko:K10119,ko:K17243	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_00501	0.0	-	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
IOFHDDHG_00502	0.0	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	Glycosyl hydrolase family 2, sugar binding domain protein
IOFHDDHG_00503	5.75e-143	maa	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Bacterial transferase hexapeptide repeat protein
IOFHDDHG_00504	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
IOFHDDHG_00505	8.51e-286	xylR	-	-	GK	-	-	-	ROK family
IOFHDDHG_00507	2.63e-48	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
IOFHDDHG_00508	4.95e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IOFHDDHG_00509	3.12e-221	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IOFHDDHG_00510	6.78e-279	-	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
IOFHDDHG_00511	8.89e-199	-	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IOFHDDHG_00512	3.09e-249	-	-	-	U	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IOFHDDHG_00513	1.19e-192	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
IOFHDDHG_00514	8.3e-160	livF	-	-	E	ko:K01995,ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOFHDDHG_00515	2.85e-146	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
IOFHDDHG_00516	1.88e-253	rfe	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 4
IOFHDDHG_00517	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IOFHDDHG_00518	2.72e-156	orn	-	-	L	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IOFHDDHG_00519	2.61e-210	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IOFHDDHG_00520	0.0	-	-	-	L	-	-	-	PIF1-like helicase
IOFHDDHG_00521	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IOFHDDHG_00522	8.85e-129	ssb2	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
IOFHDDHG_00523	0.0	pepO	3.4.24.11, 3.4.24.71	-	O	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase family M13
IOFHDDHG_00524	5.71e-193	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
IOFHDDHG_00525	0.0	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
IOFHDDHG_00526	3.71e-215	dapD	2.3.1.117	-	E	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
IOFHDDHG_00527	5e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IOFHDDHG_00528	2.95e-263	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IOFHDDHG_00529	7.14e-240	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Cell division ATP-binding protein FtsE
IOFHDDHG_00530	7.75e-206	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in cellular division
IOFHDDHG_00531	4.68e-227	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain protein
IOFHDDHG_00532	5e-106	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IOFHDDHG_00533	8.68e-207	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
IOFHDDHG_00534	1.44e-51	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
IOFHDDHG_00535	2.9e-205	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
IOFHDDHG_00536	4.41e-206	yecS	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_00537	5.24e-187	tcyC	3.6.3.21	-	E	ko:K02028,ko:K02029	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOFHDDHG_00538	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IOFHDDHG_00539	8.42e-186	-	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	RNA pseudouridylate synthase
IOFHDDHG_00540	7.33e-289	sstT	-	-	E	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IOFHDDHG_00541	1.41e-213	-	-	-	K	-	-	-	Periplasmic binding protein domain
IOFHDDHG_00542	2.99e-144	dcd	3.5.4.13	-	F	ko:K01494	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dCTP deaminase family
IOFHDDHG_00543	6.68e-196	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
IOFHDDHG_00544	0.0	nhaP	-	-	P	ko:K03316	-	ko00000	Sodium/hydrogen exchanger family
IOFHDDHG_00545	2.32e-100	tadA	3.5.4.1, 3.5.4.33	-	FJ	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IOFHDDHG_00546	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
IOFHDDHG_00547	5.18e-295	-	-	-	GK	-	-	-	ROK family
IOFHDDHG_00548	6.1e-313	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOFHDDHG_00549	2.9e-203	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_00550	1.06e-198	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_00551	0.0	-	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
IOFHDDHG_00552	1.76e-296	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
IOFHDDHG_00553	1.11e-186	cobB2	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
IOFHDDHG_00554	6.71e-39	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IOFHDDHG_00555	2.05e-178	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IOFHDDHG_00558	6.16e-28	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
IOFHDDHG_00559	3.57e-35	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
IOFHDDHG_00560	3.11e-49	-	-	-	DJ	ko:K06218	-	ko00000,ko02048	Addiction module toxin, RelE StbE family
IOFHDDHG_00563	2.78e-33	-	-	-	S	-	-	-	Domain of unknown function (DUF3846)
IOFHDDHG_00565	8.91e-12	-	-	-	-	-	-	-	-
IOFHDDHG_00568	1.57e-80	-	-	-	-	-	-	-	-
IOFHDDHG_00569	1.73e-75	-	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
IOFHDDHG_00572	1.92e-66	-	-	-	KLT	-	-	-	Protein tyrosine kinase
IOFHDDHG_00573	0.0	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
IOFHDDHG_00574	2.31e-191	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_00575	8.35e-232	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
IOFHDDHG_00576	2.22e-20	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
IOFHDDHG_00577	5.77e-180	-	-	-	-	-	-	-	-
IOFHDDHG_00578	2.87e-230	-	-	-	S	-	-	-	Conserved hypothetical protein 698
IOFHDDHG_00579	2.03e-287	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter family protein
IOFHDDHG_00580	1.54e-220	-	-	-	C	ko:K07138	-	ko00000	Domain of unknown function (DUF362)
IOFHDDHG_00581	3.76e-145	-	-	-	F	-	-	-	uridine kinase
IOFHDDHG_00582	2.03e-119	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
IOFHDDHG_00583	2.6e-176	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
IOFHDDHG_00584	3.4e-175	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IOFHDDHG_00585	5.52e-201	-	-	-	G	-	-	-	Phosphoglycerate mutase family
IOFHDDHG_00586	4.09e-290	rutG	-	-	F	ko:K02824,ko:K03458	-	ko00000,ko02000	Permease family
IOFHDDHG_00587	3.13e-163	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
IOFHDDHG_00588	0.0	-	-	-	JKL	-	-	-	helicase superfamily c-terminal domain
IOFHDDHG_00589	3.34e-173	-	-	-	V	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
IOFHDDHG_00590	2.01e-182	-	-	-	V	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOFHDDHG_00591	6.77e-306	-	-	-	S	-	-	-	Putative esterase
IOFHDDHG_00592	0.0	lysX	-	-	S	-	-	-	Uncharacterised conserved protein (DUF2156)
IOFHDDHG_00593	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IOFHDDHG_00594	8.38e-189	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
IOFHDDHG_00595	9.43e-278	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
IOFHDDHG_00596	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IOFHDDHG_00597	6.8e-227	opcA	-	-	G	-	-	-	Glucose-6-phosphate dehydrogenase subunit
IOFHDDHG_00598	1.37e-185	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
IOFHDDHG_00599	6.36e-103	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IOFHDDHG_00600	6.06e-135	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
IOFHDDHG_00601	1.87e-181	-	-	-	E	-	-	-	AzlC protein
IOFHDDHG_00602	1.96e-71	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
IOFHDDHG_00603	0.0	cstA	-	-	T	ko:K06200	-	ko00000	5TM C-terminal transporter carbon starvation CstA
IOFHDDHG_00604	1.2e-53	-	-	-	S	-	-	-	Selenoprotein, putative
IOFHDDHG_00605	4.13e-231	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
IOFHDDHG_00606	0.0	-	-	-	S	ko:K09118	-	ko00000	Uncharacterised protein family (UPF0182)
IOFHDDHG_00607	4.83e-129	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
IOFHDDHG_00608	1.42e-145	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IOFHDDHG_00609	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IOFHDDHG_00610	7.13e-313	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IOFHDDHG_00611	4.86e-97	-	-	-	D	-	-	-	Septum formation initiator
IOFHDDHG_00612	1.37e-133	-	-	-	S	ko:K09009	-	ko00000	Protein of unknown function (DUF501)
IOFHDDHG_00613	4.49e-233	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
IOFHDDHG_00615	5.27e-119	-	-	-	-	-	-	-	-
IOFHDDHG_00616	0.0	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
IOFHDDHG_00617	1.12e-95	fkbP	5.2.1.8	-	G	ko:K01802	-	ko00000,ko01000	Peptidyl-prolyl cis-trans
IOFHDDHG_00618	2.04e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IOFHDDHG_00619	6.08e-197	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
IOFHDDHG_00620	0.0	pdtaS	2.7.13.3	-	T	ko:K00936	-	ko00000,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
IOFHDDHG_00621	3.32e-61	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
IOFHDDHG_00622	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
IOFHDDHG_00623	4.21e-218	lytR2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
IOFHDDHG_00625	2.38e-299	yvhJ	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
IOFHDDHG_00626	5.69e-72	whiB2	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
IOFHDDHG_00627	0.0	-	-	-	S	-	-	-	Glycosyl transferase, family 2
IOFHDDHG_00628	1.04e-280	-	-	-	-	-	-	-	-
IOFHDDHG_00629	6.14e-93	-	-	-	S	-	-	-	Zincin-like metallopeptidase
IOFHDDHG_00630	2.56e-196	-	-	-	T	-	-	-	Eukaryotic phosphomannomutase
IOFHDDHG_00631	1.98e-179	pyrE_1	-	-	S	-	-	-	Phosphoribosyl transferase domain
IOFHDDHG_00632	1.99e-238	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
IOFHDDHG_00633	1.74e-165	cseB	-	-	T	-	-	-	Response regulator receiver domain protein
IOFHDDHG_00634	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IOFHDDHG_00635	8.46e-133	carD	-	-	K	ko:K07736	-	ko00000,ko03000	CarD-like/TRCF domain
IOFHDDHG_00636	3.22e-114	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
IOFHDDHG_00637	4.53e-179	znuB	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
IOFHDDHG_00638	7.98e-205	-	-	-	P	ko:K02074	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOFHDDHG_00639	2.46e-232	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
IOFHDDHG_00640	2.73e-207	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IOFHDDHG_00641	0.0	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
IOFHDDHG_00642	1.09e-149	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IOFHDDHG_00643	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IOFHDDHG_00644	2.78e-225	terC	-	-	P	ko:K05794	-	ko00000	Integral membrane protein, TerC family
IOFHDDHG_00645	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
IOFHDDHG_00647	1.02e-25	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
IOFHDDHG_00649	2.27e-244	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
IOFHDDHG_00650	2.48e-146	ehuA	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOFHDDHG_00651	1.58e-158	-	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Bacterial periplasmic substrate-binding proteins
IOFHDDHG_00652	4.5e-132	tcyA/tcyB	-	-	E	ko:K02029,ko:K02030,ko:K02424,ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_00653	1.68e-44	-	-	-	F	-	-	-	DNA helicase
IOFHDDHG_00654	0.0	-	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
IOFHDDHG_00655	1.91e-307	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	HsdM N-terminal domain
IOFHDDHG_00656	4.44e-46	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
IOFHDDHG_00657	6.35e-69	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain protein
IOFHDDHG_00658	1.2e-133	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IOFHDDHG_00660	1.62e-212	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
IOFHDDHG_00661	8.64e-156	pdtaR	-	-	T	ko:K22010	-	ko00000,ko00002,ko02022	Response regulator receiver domain protein
IOFHDDHG_00662	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IOFHDDHG_00663	5.82e-221	-	-	-	L	-	-	-	NIF3 (NGG1p interacting factor 3)
IOFHDDHG_00664	4.34e-159	-	-	-	L	-	-	-	NUDIX domain
IOFHDDHG_00665	0.0	glgX	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
IOFHDDHG_00666	1.18e-271	-	-	-	-	-	-	-	-
IOFHDDHG_00668	0.0	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IOFHDDHG_00669	0.0	-	-	-	-	-	-	-	-
IOFHDDHG_00670	1.39e-149	-	-	-	-	-	-	-	-
IOFHDDHG_00671	1.73e-83	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
IOFHDDHG_00672	8.18e-35	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IOFHDDHG_00673	3.83e-76	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IOFHDDHG_00674	3.54e-35	-	-	-	-	-	-	-	-
IOFHDDHG_00675	3.67e-88	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IOFHDDHG_00676	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
IOFHDDHG_00677	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
IOFHDDHG_00678	0.0	pta	2.3.1.8	-	C	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphate acetyltransferase
IOFHDDHG_00679	8.03e-296	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IOFHDDHG_00680	0.0	yrhL	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
IOFHDDHG_00681	6.08e-312	pbuX	-	-	F	ko:K03458	-	ko00000	Permease family
IOFHDDHG_00682	2.66e-138	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IOFHDDHG_00683	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
IOFHDDHG_00684	3.23e-80	-	-	-	S	-	-	-	Domain of unknown function (DUF4418)
IOFHDDHG_00685	1.68e-274	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IOFHDDHG_00686	1.23e-190	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IOFHDDHG_00687	2.23e-142	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IOFHDDHG_00688	2.8e-74	-	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
IOFHDDHG_00689	9.46e-167	-	5.4.2.12	-	G	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
IOFHDDHG_00690	8.09e-79	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
IOFHDDHG_00691	6.83e-50	-	-	-	-	-	-	-	-
IOFHDDHG_00692	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IOFHDDHG_00693	1.06e-106	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IOFHDDHG_00694	2.36e-253	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IOFHDDHG_00695	3.69e-95	-	3.4.23.43	-	S	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
IOFHDDHG_00696	6.68e-282	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IOFHDDHG_00697	0.0	aroB	2.7.1.71, 4.2.3.4	-	H	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IOFHDDHG_00698	3.9e-105	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
IOFHDDHG_00699	0.0	-	3.2.1.1, 3.2.1.41	CBM48,GH13	M	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	Aamy_C
IOFHDDHG_00700	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IOFHDDHG_00701	0.0	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
IOFHDDHG_00702	0.0	sufB	-	-	O	ko:K09014	-	ko00000	FeS assembly protein SufB
IOFHDDHG_00703	4.32e-299	sufD	-	-	O	ko:K09015	-	ko00000	FeS assembly protein SufD
IOFHDDHG_00704	1.14e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
IOFHDDHG_00705	7.57e-304	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IOFHDDHG_00706	6.78e-128	iscU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
IOFHDDHG_00707	3.77e-139	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
IOFHDDHG_00708	5.57e-310	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IOFHDDHG_00709	5e-207	spoU2	-	-	J	-	-	-	SpoU rRNA Methylase family
IOFHDDHG_00711	9.78e-188	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IOFHDDHG_00712	1.81e-74	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
IOFHDDHG_00713	4.06e-267	phoH	-	-	T	ko:K06217	-	ko00000	PhoH-like protein
IOFHDDHG_00714	1.14e-133	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IOFHDDHG_00715	0.0	corC	-	-	S	-	-	-	CBS domain
IOFHDDHG_00716	2.58e-228	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IOFHDDHG_00717	0.0	fadD2	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
IOFHDDHG_00718	1.39e-259	pntA	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	NAD(P) transhydrogenase subunit alpha part 1 K00324
IOFHDDHG_00719	1.02e-57	pntAB	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	4TM region of pyridine nucleotide transhydrogenase, mitoch
IOFHDDHG_00720	0.0	pntB	1.6.1.2	-	C	ko:K00325	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IOFHDDHG_00721	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
IOFHDDHG_00723	7.88e-287	-	-	-	G	-	-	-	Transmembrane secretion effector
IOFHDDHG_00724	5.26e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOFHDDHG_00725	3.96e-53	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
IOFHDDHG_00726	2.67e-96	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
IOFHDDHG_00727	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IOFHDDHG_00729	2.96e-242	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IOFHDDHG_00730	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IOFHDDHG_00731	3.74e-41	-	-	-	EGP	ko:K08177,ko:K19577	-	ko00000,ko02000	Major facilitator Superfamily
IOFHDDHG_00732	1.37e-33	yhjX	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major facilitator Superfamily
IOFHDDHG_00733	1.08e-249	-	-	-	S	ko:K06889	-	ko00000	alpha beta
IOFHDDHG_00734	1.29e-127	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IOFHDDHG_00735	4.21e-121	-	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOFHDDHG_00736	2.02e-76	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOFHDDHG_00737	2.62e-95	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IOFHDDHG_00739	8.14e-290	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Amino-transferase class IV
IOFHDDHG_00740	3.02e-174	-	-	-	S	-	-	-	UPF0126 domain
IOFHDDHG_00741	7.89e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
IOFHDDHG_00742	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IOFHDDHG_00743	1.82e-297	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
IOFHDDHG_00744	1.39e-187	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
IOFHDDHG_00745	0.0	-	-	-	C	-	-	-	Acyl-CoA reductase (LuxC)
IOFHDDHG_00746	7.44e-278	-	-	-	H	-	-	-	long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase
IOFHDDHG_00747	9.48e-299	-	-	-	F	-	-	-	Psort location CytoplasmicMembrane, score 10.00
IOFHDDHG_00748	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase NADPH large subunit
IOFHDDHG_00749	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
IOFHDDHG_00750	3.85e-98	-	-	-	-	-	-	-	-
IOFHDDHG_00751	9.94e-317	glgA	2.4.1.342	GT4	G	ko:K16148	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Starch synthase catalytic domain
IOFHDDHG_00752	2.73e-203	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOFHDDHG_00753	2.79e-253	trmI	2.1.1.219, 2.1.1.220	-	J	ko:K07442	-	ko00000,ko01000,ko03016	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
IOFHDDHG_00754	1.67e-128	sixA	-	-	T	ko:K08296	-	ko00000,ko01000	Phosphoglycerate mutase family
IOFHDDHG_00755	4.72e-307	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
IOFHDDHG_00757	1.51e-27	-	-	-	S	-	-	-	Predicted membrane protein (DUF2335)
IOFHDDHG_00758	1.02e-46	-	-	-	N	-	-	-	HicA toxin of bacterial toxin-antitoxin,
IOFHDDHG_00759	4.84e-71	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0150
IOFHDDHG_00760	4.6e-113	-	-	-	-	-	-	-	-
IOFHDDHG_00761	9.49e-41	-	-	-	-	-	-	-	-
IOFHDDHG_00762	8.61e-132	-	-	-	S	ko:K14623	-	ko00000,ko03400	SOS response
IOFHDDHG_00763	5.14e-82	-	-	-	-	-	-	-	-
IOFHDDHG_00764	2.74e-46	-	-	-	-	-	-	-	-
IOFHDDHG_00767	4.95e-176	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
IOFHDDHG_00769	1.83e-49	-	-	-	-	-	-	-	-
IOFHDDHG_00772	2.44e-05	-	-	-	-	-	-	-	-
IOFHDDHG_00773	3.95e-45	-	-	-	-	-	-	-	-
IOFHDDHG_00775	7.3e-103	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
IOFHDDHG_00776	2.08e-178	-	-	-	K	-	-	-	Transcriptional regulator
IOFHDDHG_00777	1.79e-34	-	-	-	-	-	-	-	-
IOFHDDHG_00778	1.72e-103	-	-	-	V	-	-	-	HNH endonuclease
IOFHDDHG_00779	9.25e-134	-	-	-	A	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IOFHDDHG_00785	3.77e-23	-	-	-	-	-	-	-	-
IOFHDDHG_00786	5.77e-211	-	-	-	J	-	-	-	tRNA 5'-leader removal
IOFHDDHG_00787	1.29e-66	-	-	-	V	-	-	-	HNH nucleases
IOFHDDHG_00788	1.44e-48	-	-	-	-	-	-	-	-
IOFHDDHG_00789	6.1e-289	-	-	-	S	-	-	-	Terminase
IOFHDDHG_00790	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
IOFHDDHG_00791	2.39e-139	-	-	-	-	-	-	-	-
IOFHDDHG_00793	1.14e-98	-	-	-	-	-	-	-	-
IOFHDDHG_00794	1.82e-197	-	-	-	V	-	-	-	Phage capsid family
IOFHDDHG_00796	1e-83	-	-	-	S	-	-	-	Phage protein Gp19/Gp15/Gp42
IOFHDDHG_00797	2.83e-60	-	-	-	-	-	-	-	-
IOFHDDHG_00798	5.04e-43	-	-	-	-	-	-	-	-
IOFHDDHG_00799	2.76e-81	-	-	-	-	-	-	-	-
IOFHDDHG_00800	3.18e-141	-	-	-	-	-	-	-	-
IOFHDDHG_00801	1.57e-84	-	-	-	-	-	-	-	-
IOFHDDHG_00803	0.0	-	-	-	S	-	-	-	phage tail tape measure protein
IOFHDDHG_00804	1.86e-181	-	-	-	-	-	-	-	-
IOFHDDHG_00805	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
IOFHDDHG_00807	2.15e-118	-	-	-	-	-	-	-	-
IOFHDDHG_00808	6.91e-41	-	-	-	-	-	-	-	-
IOFHDDHG_00809	1.01e-41	-	-	-	-	-	-	-	-
IOFHDDHG_00810	5.91e-117	-	-	-	L	-	-	-	DNA integration
IOFHDDHG_00811	1.47e-31	-	-	-	-	-	-	-	-
IOFHDDHG_00812	2.61e-68	-	-	-	MU	-	-	-	outer membrane autotransporter barrel domain protein
IOFHDDHG_00814	9.07e-05	-	-	-	-	-	-	-	-
IOFHDDHG_00816	2.44e-250	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
IOFHDDHG_00817	1.16e-39	-	-	-	S	-	-	-	Putative phage holin Dp-1
IOFHDDHG_00818	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IOFHDDHG_00819	1.42e-202	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
IOFHDDHG_00820	0.0	glnE	2.7.7.42, 2.7.7.89	-	H	ko:K00982	-	ko00000,ko01000	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
IOFHDDHG_00821	8.48e-241	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
IOFHDDHG_00822	1.06e-96	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
IOFHDDHG_00823	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IOFHDDHG_00824	1.44e-228	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
IOFHDDHG_00825	5.08e-198	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
IOFHDDHG_00826	8.22e-230	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IOFHDDHG_00827	9.36e-160	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IOFHDDHG_00828	6.03e-210	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
IOFHDDHG_00829	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IOFHDDHG_00830	9.59e-141	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IOFHDDHG_00831	4.36e-89	arsC	1.20.4.1, 2.8.4.2	-	T	ko:K03741,ko:K18701	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IOFHDDHG_00832	1.56e-277	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
IOFHDDHG_00833	1.43e-154	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
IOFHDDHG_00834	6.64e-67	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
IOFHDDHG_00835	5.87e-180	-	-	-	S	-	-	-	SdpI/YhfL protein family
IOFHDDHG_00836	4.54e-157	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IOFHDDHG_00837	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IOFHDDHG_00838	3.1e-160	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IOFHDDHG_00841	1.81e-81	-	-	-	-	-	-	-	-
IOFHDDHG_00842	9.76e-125	-	-	-	M	-	-	-	Peptidase family M23
IOFHDDHG_00843	0.0	fadD1	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
IOFHDDHG_00844	0.0	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
IOFHDDHG_00845	1.58e-305	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
IOFHDDHG_00846	1.07e-265	guaB3	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase family protein
IOFHDDHG_00847	5.78e-139	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease, DNA polymerase III, epsilon subunit family
IOFHDDHG_00848	3.58e-93	-	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IOFHDDHG_00849	5.69e-315	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IOFHDDHG_00850	3.94e-88	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IOFHDDHG_00851	2.1e-182	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
IOFHDDHG_00852	2.07e-168	-	-	-	-	-	-	-	-
IOFHDDHG_00854	6.91e-298	-	-	-	K	-	-	-	Fic/DOC family
IOFHDDHG_00855	4.75e-92	pdxH	-	-	S	ko:K07006	-	ko00000	Pfam:Pyridox_oxidase
IOFHDDHG_00856	0.0	-	-	-	M	-	-	-	domain protein
IOFHDDHG_00859	1.72e-210	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
IOFHDDHG_00860	1.48e-219	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
IOFHDDHG_00861	1.11e-181	-	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
IOFHDDHG_00862	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
IOFHDDHG_00863	1.6e-137	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
IOFHDDHG_00864	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
IOFHDDHG_00865	2.13e-228	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
IOFHDDHG_00866	7.17e-119	tsaE	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
IOFHDDHG_00867	5.66e-189	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Glycoprotease family
IOFHDDHG_00868	7.04e-133	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	FR47-like protein
IOFHDDHG_00869	3.79e-249	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IOFHDDHG_00871	4.62e-152	yoaP	-	-	E	-	-	-	YoaP-like
IOFHDDHG_00872	7.51e-238	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IOFHDDHG_00873	3.51e-154	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
IOFHDDHG_00874	2.39e-93	-	-	-	K	-	-	-	MerR family regulatory protein
IOFHDDHG_00875	2.21e-253	adh	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
IOFHDDHG_00876	1.31e-185	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
IOFHDDHG_00877	7.46e-282	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
IOFHDDHG_00878	5.77e-100	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IOFHDDHG_00879	5.23e-233	-	-	-	P	-	-	-	Cation efflux family
IOFHDDHG_00882	1.62e-141	-	-	-	-	ko:K03646	-	ko00000,ko02000	-
IOFHDDHG_00883	1.59e-195	-	-	-	-	-	-	-	-
IOFHDDHG_00884	7.76e-186	mazG	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	Psort location Cytoplasmic, score 8.87
IOFHDDHG_00885	0.0	-	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
IOFHDDHG_00886	6.85e-216	-	-	-	S	-	-	-	IMP dehydrogenase activity
IOFHDDHG_00887	0.0	ybiT	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
IOFHDDHG_00888	5.54e-144	pncA	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Isochorismatase family
IOFHDDHG_00889	4.53e-88	ogt	2.1.1.63	-	L	ko:K00567,ko:K07443	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IOFHDDHG_00891	2.77e-19	-	-	-	-	-	-	-	-
IOFHDDHG_00892	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
IOFHDDHG_00893	3.25e-179	-	-	-	S	-	-	-	Domain of unknown function (DUF4194)
IOFHDDHG_00894	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
IOFHDDHG_00895	4.14e-280	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
IOFHDDHG_00896	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IOFHDDHG_00897	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IOFHDDHG_00898	9.81e-233	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate dehydrogenase substrate binding domain
IOFHDDHG_00899	4.41e-218	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
IOFHDDHG_00900	2.1e-219	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
IOFHDDHG_00901	3.72e-281	pgk	2.7.2.3, 5.3.1.1	-	F	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
IOFHDDHG_00902	5.69e-191	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IOFHDDHG_00903	4.98e-44	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
IOFHDDHG_00904	1.58e-208	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IOFHDDHG_00905	0.0	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase, class I II
IOFHDDHG_00907	2.36e-138	-	-	-	H	ko:K03811	-	ko00000,ko02000	Nicotinamide mononucleotide transporter
IOFHDDHG_00908	3.88e-55	nadR	-	-	H	-	-	-	ATPase kinase involved in NAD metabolism
IOFHDDHG_00909	4.69e-260	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IOFHDDHG_00910	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
IOFHDDHG_00911	7.99e-251	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IOFHDDHG_00912	6.98e-265	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IOFHDDHG_00913	6.46e-201	-	-	-	G	-	-	-	Fructosamine kinase
IOFHDDHG_00914	1.44e-199	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IOFHDDHG_00915	2.29e-199	-	-	-	S	-	-	-	PAC2 family
IOFHDDHG_00923	3.74e-48	-	-	-	-	-	-	-	-
IOFHDDHG_00924	2.22e-98	garA	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
IOFHDDHG_00925	2.15e-144	merR2	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IOFHDDHG_00926	1.54e-80	-	-	-	-	-	-	-	-
IOFHDDHG_00927	5.93e-181	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
IOFHDDHG_00928	2.24e-81	rbpA	-	-	K	-	-	-	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
IOFHDDHG_00929	0.0	helY	-	-	L	ko:K03727	-	ko00000,ko01000	DEAD DEAH box helicase
IOFHDDHG_00930	2.4e-73	-	-	-	-	-	-	-	-
IOFHDDHG_00931	0.0	-	-	-	K	-	-	-	WYL domain
IOFHDDHG_00932	0.0	ugp	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
IOFHDDHG_00934	8.64e-92	-	-	-	-	-	-	-	-
IOFHDDHG_00935	0.0	der	-	-	F	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
IOFHDDHG_00936	9.79e-184	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IOFHDDHG_00937	8.38e-208	-	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
IOFHDDHG_00938	1.69e-48	-	-	-	-	-	-	-	-
IOFHDDHG_00939	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
IOFHDDHG_00940	0.0	-	-	-	-	-	-	-	-
IOFHDDHG_00941	1.1e-205	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IOFHDDHG_00942	5.48e-281	sucC	6.2.1.5	-	F	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
IOFHDDHG_00943	5.27e-130	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IOFHDDHG_00944	3.98e-83	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
IOFHDDHG_00945	3.38e-256	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IOFHDDHG_00946	1.34e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IOFHDDHG_00947	2.73e-129	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IOFHDDHG_00948	2.38e-172	yebC	-	-	K	-	-	-	transcriptional regulatory protein
IOFHDDHG_00949	2.88e-144	pgsA1	2.7.8.11, 2.7.8.5	-	I	ko:K00995,ko:K00999	ko00562,ko00564,ko01100,ko04070,map00562,map00564,map01100,map04070	ko00000,ko00001,ko01000	CDP-alcohol phosphatidyltransferase
IOFHDDHG_00950	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IOFHDDHG_00951	3.22e-182	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
IOFHDDHG_00952	2.68e-64	sbp	-	-	S	-	-	-	Protein of unknown function (DUF1290)
IOFHDDHG_00953	3.77e-221	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
IOFHDDHG_00954	8.44e-134	pgsA2	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IOFHDDHG_00955	1.24e-199	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
IOFHDDHG_00956	1.2e-54	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-ATP pyrophosphohydrolase
IOFHDDHG_00957	2.25e-137	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3-epimerase
IOFHDDHG_00958	2.39e-231	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IOFHDDHG_00959	3.89e-208	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IOFHDDHG_00960	0.0	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IOFHDDHG_00961	0.0	trpE	4.1.3.27	-	E	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IOFHDDHG_00962	1.12e-95	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IOFHDDHG_00963	5.63e-178	hisF	4.1.3.27	-	E	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IOFHDDHG_00964	6.47e-287	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IOFHDDHG_00965	5.62e-228	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
IOFHDDHG_00966	4.41e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IOFHDDHG_00967	1.67e-171	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
IOFHDDHG_00969	6.23e-184	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IOFHDDHG_00970	7.95e-183	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
IOFHDDHG_00971	1.22e-107	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IOFHDDHG_00972	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	long-chain-fatty acid CoA ligase
IOFHDDHG_00973	2.07e-156	-	-	-	-	-	-	-	-
IOFHDDHG_00975	2.47e-235	intA	-	-	L	-	-	-	Phage integrase family
IOFHDDHG_00977	9.52e-231	-	-	-	M	-	-	-	Bacteriophage peptidoglycan hydrolase
IOFHDDHG_00980	1.02e-120	-	-	-	-	-	-	-	-
IOFHDDHG_00981	4.12e-265	-	-	-	-	-	-	-	-
IOFHDDHG_00984	6.4e-123	-	-	-	-	-	-	-	-
IOFHDDHG_00985	7.53e-218	-	-	-	S	-	-	-	HipA-like C-terminal domain
IOFHDDHG_00987	1.72e-93	-	-	-	-	ko:K03646	-	ko00000,ko02000	-
IOFHDDHG_00988	0.0	-	-	-	D	-	-	-	Cell surface antigen C-terminus
IOFHDDHG_00991	0.0	-	-	-	U	-	-	-	Type IV secretory pathway, VirB4
IOFHDDHG_00992	0.0	-	-	-	U	-	-	-	TraM recognition site of TraD and TraG
IOFHDDHG_01001	1.3e-242	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	DNA topoisomerase
IOFHDDHG_01004	8.64e-76	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
IOFHDDHG_01005	9.02e-126	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
IOFHDDHG_01006	2.37e-30	-	-	-	-	-	-	-	-
IOFHDDHG_01007	0.0	-	-	-	L	-	-	-	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IOFHDDHG_01014	8.19e-108	-	-	-	L	-	-	-	helicase
IOFHDDHG_01015	4.42e-15	-	-	-	-	-	-	-	-
IOFHDDHG_01018	1.06e-125	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease, DNA polymerase III, epsilon subunit family
IOFHDDHG_01019	1.5e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF2786)
IOFHDDHG_01026	8.16e-30	-	-	-	-	-	-	-	-
IOFHDDHG_01028	1.45e-81	-	-	-	S	-	-	-	Glutamine amidotransferases class-II
IOFHDDHG_01029	1.54e-52	-	-	-	-	-	-	-	-
IOFHDDHG_01030	2.15e-47	-	-	-	K	-	-	-	sequence-specific DNA binding
IOFHDDHG_01032	2.69e-76	-	-	-	L	-	-	-	EcoRII C terminal
IOFHDDHG_01033	2.02e-92	-	-	-	L	-	-	-	Resolvase, N terminal domain
IOFHDDHG_01036	4.97e-166	-	3.6.4.12	-	F	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RecQ zinc-binding
IOFHDDHG_01039	1.25e-78	-	-	-	V	-	-	-	Restriction endonuclease
IOFHDDHG_01042	9.2e-18	-	-	-	-	-	-	-	-
IOFHDDHG_01043	0.0	-	-	-	DZ	-	-	-	Regulator of chromosome condensation (RCC1) repeat
IOFHDDHG_01044	4.31e-100	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
IOFHDDHG_01045	3.59e-123	-	-	-	M	-	-	-	domain protein
IOFHDDHG_01046	1.64e-22	-	-	-	M	-	-	-	Listeria-Bacteroides repeat domain (List_Bact_rpt)
IOFHDDHG_01048	3.07e-51	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
IOFHDDHG_01049	2.3e-54	-	-	-	M	-	-	-	domain protein
IOFHDDHG_01050	1.32e-103	-	-	-	-	-	-	-	-
IOFHDDHG_01051	2.09e-121	-	-	-	S	-	-	-	Fic/DOC family
IOFHDDHG_01052	2.14e-18	-	-	-	-	-	-	-	-
IOFHDDHG_01059	1.32e-31	-	-	-	O	-	-	-	COG0464 ATPases of the AAA class
IOFHDDHG_01063	1.25e-92	ydhQ	2.7.11.1	-	MU	ko:K12132	-	ko00000,ko01000,ko01001	cell adhesion
IOFHDDHG_01067	1.67e-241	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IOFHDDHG_01068	1.1e-180	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IOFHDDHG_01069	1.59e-130	-	-	-	-	-	-	-	-
IOFHDDHG_01070	4.12e-310	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IOFHDDHG_01071	0.0	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IOFHDDHG_01072	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase N terminus
IOFHDDHG_01073	5.66e-295	-	-	-	EGP	-	-	-	Transporter major facilitator family protein
IOFHDDHG_01074	3.37e-135	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
IOFHDDHG_01075	4.61e-221	-	-	-	G	-	-	-	Fic/DOC family
IOFHDDHG_01076	4.19e-185	-	-	-	-	-	-	-	-
IOFHDDHG_01077	9.96e-209	-	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
IOFHDDHG_01078	3.4e-208	-	-	-	S	-	-	-	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IOFHDDHG_01079	1.18e-73	-	3.4.13.22	-	S	ko:K08641,ko:K11206	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IOFHDDHG_01080	1.63e-122	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Redoxin
IOFHDDHG_01081	5.7e-06	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
IOFHDDHG_01082	3.11e-124	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
IOFHDDHG_01084	0.0	-	-	-	S	-	-	-	Histidine phosphatase superfamily (branch 2)
IOFHDDHG_01085	1.13e-59	-	-	-	L	-	-	-	transposition
IOFHDDHG_01086	2.66e-31	-	-	-	C	-	-	-	Acetamidase/Formamidase family
IOFHDDHG_01087	5.29e-78	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
IOFHDDHG_01088	1.95e-221	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOFHDDHG_01089	2.24e-150	-	-	-	S	-	-	-	ABC-2 family transporter protein
IOFHDDHG_01090	3.57e-158	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
IOFHDDHG_01091	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
IOFHDDHG_01092	2.71e-228	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IOFHDDHG_01093	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
IOFHDDHG_01094	1.25e-150	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
IOFHDDHG_01095	4.79e-173	tlyA	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
IOFHDDHG_01096	8.87e-245	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
IOFHDDHG_01097	2.68e-222	-	-	-	L	-	-	-	Tetratricopeptide repeat
IOFHDDHG_01098	1.91e-316	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IOFHDDHG_01099	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
IOFHDDHG_01100	1.01e-181	-	-	-	S	-	-	-	Putative ABC-transporter type IV
IOFHDDHG_01101	4.08e-123	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
IOFHDDHG_01102	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
IOFHDDHG_01103	4.33e-303	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
IOFHDDHG_01104	1.91e-109	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
IOFHDDHG_01105	9.86e-237	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IOFHDDHG_01106	5.56e-305	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
IOFHDDHG_01107	5.02e-228	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
IOFHDDHG_01108	1.33e-273	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IOFHDDHG_01109	1.16e-263	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IOFHDDHG_01110	7.69e-148	-	-	-	-	-	-	-	-
IOFHDDHG_01111	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Phenylalanyl-tRNA synthetase beta
IOFHDDHG_01112	9.1e-261	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IOFHDDHG_01114	5.91e-14	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IOFHDDHG_01115	3.02e-124	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Possible lysine decarboxylase
IOFHDDHG_01116	2.06e-25	-	-	-	-	-	-	-	-
IOFHDDHG_01118	2.76e-15	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	HNH endonuclease
IOFHDDHG_01119	9.27e-146	-	-	-	L	-	-	-	Uracil DNA glycosylase superfamily
IOFHDDHG_01120	1.52e-19	-	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
IOFHDDHG_01121	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
IOFHDDHG_01122	5.03e-183	-	-	-	S	-	-	-	Domain of unknown function (DUF4191)
IOFHDDHG_01123	7.43e-314	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IOFHDDHG_01124	1.66e-126	-	-	-	S	-	-	-	Protein of unknown function (DUF3043)
IOFHDDHG_01125	0.0	argE	-	-	E	-	-	-	Peptidase dimerisation domain
IOFHDDHG_01126	1.27e-186	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
IOFHDDHG_01127	0.0	ykoD	-	-	P	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOFHDDHG_01128	1.53e-108	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
IOFHDDHG_01129	4.1e-272	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
IOFHDDHG_01130	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IOFHDDHG_01131	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
IOFHDDHG_01132	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IOFHDDHG_01133	0.0	-	2.8.2.22	-	S	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
IOFHDDHG_01134	6.33e-186	-	-	-	P	ko:K16784	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOFHDDHG_01135	2.89e-281	-	-	-	E	-	-	-	Aminotransferase class I and II
IOFHDDHG_01136	3.28e-181	ppgK	2.7.1.2, 2.7.1.63	-	GK	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
IOFHDDHG_01137	2.22e-258	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
IOFHDDHG_01138	5.48e-189	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IOFHDDHG_01139	3.73e-63	-	-	-	J	ko:K07574	-	ko00000,ko03009	CRS1_YhbY
IOFHDDHG_01140	0.0	-	-	-	GP	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IOFHDDHG_01141	1.61e-138	-	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IOFHDDHG_01142	0.0	-	-	-	KL	-	-	-	Psort location Cytoplasmic, score 8.87
IOFHDDHG_01143	4.94e-149	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
IOFHDDHG_01144	6.98e-241	-	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
IOFHDDHG_01145	1.81e-108	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IOFHDDHG_01146	1.79e-159	-	-	-	S	-	-	-	alpha beta
IOFHDDHG_01148	1.16e-52	-	-	-	S	-	-	-	Protein of unknown function DUF262
IOFHDDHG_01149	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
IOFHDDHG_01150	0.0	-	-	-	S	ko:K06915	-	ko00000	AAA-like domain
IOFHDDHG_01151	2.03e-68	-	-	-	S	-	-	-	SIR2-like domain
IOFHDDHG_01152	3.16e-235	-	-	-	V	-	-	-	Type III restriction enzyme res subunit
IOFHDDHG_01153	8.16e-70	-	-	-	L	-	-	-	Eco57I restriction-modification methylase
IOFHDDHG_01154	1.76e-137	-	-	-	L	-	-	-	Eco57I restriction-modification methylase
IOFHDDHG_01155	0.0	-	-	-	KL	-	-	-	Type III restriction enzyme res subunit
IOFHDDHG_01156	1.03e-173	-	-	-	-	-	-	-	-
IOFHDDHG_01157	2.36e-55	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative DNA-binding domain
IOFHDDHG_01158	7.66e-83	-	-	-	S	-	-	-	Putative inner membrane protein (DUF1819)
IOFHDDHG_01159	7.71e-32	-	-	-	-	-	-	-	-
IOFHDDHG_01160	3.33e-92	-	-	-	-	-	-	-	-
IOFHDDHG_01161	7.25e-270	-	-	-	-	-	-	-	-
IOFHDDHG_01162	2.85e-203	-	-	-	S	-	-	-	phosphoesterase or phosphohydrolase
IOFHDDHG_01163	6.26e-53	-	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
IOFHDDHG_01164	1.29e-28	-	1.1.1.91	-	C	ko:K05882	-	ko00000,ko01000	Aldo/keto reductase family
IOFHDDHG_01165	7.83e-172	-	2.7.13.3	-	T	ko:K07675	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOFHDDHG_01166	1.14e-156	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
IOFHDDHG_01167	0.0	-	-	-	KLT	-	-	-	Lanthionine synthetase C-like protein
IOFHDDHG_01168	5.12e-194	-	-	-	KLT	-	-	-	serine threonine protein kinase
IOFHDDHG_01169	4.66e-68	-	3.6.3.44	-	V	ko:K06147,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
IOFHDDHG_01170	1.16e-96	-	3.6.3.44	-	V	ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
IOFHDDHG_01171	2.91e-202	-	-	-	O	-	-	-	Thioredoxin
IOFHDDHG_01172	1.23e-167	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
IOFHDDHG_01173	2.84e-169	-	-	-	S	-	-	-	DUF218 domain
IOFHDDHG_01174	6.96e-301	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IOFHDDHG_01175	1.7e-299	rnd	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
IOFHDDHG_01176	3.3e-102	-	-	-	S	-	-	-	Protein of unknown function (DUF3000)
IOFHDDHG_01177	1.02e-209	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IOFHDDHG_01178	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
IOFHDDHG_01179	1.28e-41	-	-	-	-	-	-	-	-
IOFHDDHG_01180	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IOFHDDHG_01181	1.58e-286	-	-	-	S	-	-	-	Peptidase dimerisation domain
IOFHDDHG_01182	6.44e-198	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IOFHDDHG_01183	3.14e-192	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
IOFHDDHG_01184	4.13e-188	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IOFHDDHG_01185	1.59e-144	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_01186	5.59e-58	-	-	-	-	-	-	-	-
IOFHDDHG_01188	5.29e-131	-	-	-	V	-	-	-	Abi-like protein
IOFHDDHG_01189	4.76e-83	-	-	-	L	-	-	-	Helix-turn-helix domain
IOFHDDHG_01191	0.0	-	-	-	S	-	-	-	LPXTG-motif cell wall anchor domain protein
IOFHDDHG_01192	1.5e-162	dinF	-	-	V	-	-	-	MatE
IOFHDDHG_01193	6.43e-133	dinF	-	-	V	-	-	-	MatE
IOFHDDHG_01194	7.75e-130	ppiA	5.2.1.8	-	G	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IOFHDDHG_01195	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IOFHDDHG_01196	4.13e-109	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
IOFHDDHG_01197	8.5e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4193)
IOFHDDHG_01198	9.2e-227	-	-	-	S	-	-	-	Protein of unknown function (DUF3071)
IOFHDDHG_01199	1.45e-299	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
IOFHDDHG_01200	0.0	gyrA2	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
IOFHDDHG_01201	0.0	lhr	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
IOFHDDHG_01202	7.27e-42	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
IOFHDDHG_01203	7.86e-103	-	-	-	S	-	-	-	Protein of unknown function (DUF2975)
IOFHDDHG_01204	2.21e-309	-	-	-	T	-	-	-	Domain of unknown function (DUF4173)
IOFHDDHG_01205	4.22e-287	-	-	-	G	-	-	-	Major Facilitator Superfamily
IOFHDDHG_01206	0.0	gyrB2	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
IOFHDDHG_01207	3.32e-226	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IOFHDDHG_01208	2.58e-152	-	-	-	-	-	-	-	-
IOFHDDHG_01209	3e-250	idsA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IOFHDDHG_01210	0.0	pknL	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	PASTA
IOFHDDHG_01211	3.04e-171	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
IOFHDDHG_01212	4.49e-129	-	-	-	-	-	-	-	-
IOFHDDHG_01213	1.53e-245	trpD	2.4.2.18	-	F	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IOFHDDHG_01214	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IOFHDDHG_01215	5.45e-153	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IOFHDDHG_01216	4.3e-158	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
IOFHDDHG_01217	4.97e-271	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IOFHDDHG_01218	6.62e-61	-	-	-	S	-	-	-	Protein of unknown function (DUF3046)
IOFHDDHG_01219	7.73e-104	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IOFHDDHG_01220	7.04e-127	cinA	3.5.1.42	-	S	ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
IOFHDDHG_01221	1.29e-159	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IOFHDDHG_01222	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE family protein
IOFHDDHG_01223	4.58e-246	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IOFHDDHG_01224	0.0	miaB	2.8.4.3	-	H	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IOFHDDHG_01225	6.96e-201	ywaC	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
IOFHDDHG_01226	9.71e-228	-	-	-	EG	-	-	-	EamA-like transporter family
IOFHDDHG_01227	4.11e-170	-	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
IOFHDDHG_01228	2.71e-145	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
IOFHDDHG_01229	3.12e-310	-	-	-	T	-	-	-	Histidine kinase
IOFHDDHG_01230	8.7e-166	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
IOFHDDHG_01231	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
IOFHDDHG_01232	3.27e-150	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
IOFHDDHG_01233	6.34e-312	-	-	-	T	-	-	-	Histidine kinase
IOFHDDHG_01234	1.72e-242	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOFHDDHG_01235	8.53e-287	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IOFHDDHG_01236	1.74e-62	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IOFHDDHG_01237	2.31e-213	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IOFHDDHG_01238	2.23e-265	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IOFHDDHG_01239	5.47e-151	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Bacterial transferase hexapeptide repeat protein
IOFHDDHG_01240	0.0	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 9.99
IOFHDDHG_01241	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IOFHDDHG_01242	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
IOFHDDHG_01243	2.14e-98	-	-	-	-	-	-	-	-
IOFHDDHG_01244	1.13e-308	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IOFHDDHG_01245	1.09e-171	-	-	-	S	-	-	-	Protein of unknown function (DUF3159)
IOFHDDHG_01246	1.49e-193	-	-	-	S	-	-	-	Protein of unknown function (DUF3710)
IOFHDDHG_01247	1.67e-219	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
IOFHDDHG_01248	0.0	-	-	-	EP	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
IOFHDDHG_01249	1.18e-223	dppC	-	-	EP	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
IOFHDDHG_01250	1.45e-206	dppB	-	-	EP	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_01251	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
IOFHDDHG_01252	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
IOFHDDHG_01253	2.28e-219	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
IOFHDDHG_01255	2.28e-35	-	-	-	-	-	-	-	-
IOFHDDHG_01256	2.11e-250	tyrA	1.3.1.12	-	E	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
IOFHDDHG_01257	1.86e-243	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
IOFHDDHG_01258	3.37e-134	-	-	-	-	-	-	-	-
IOFHDDHG_01259	0.0	typA	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
IOFHDDHG_01260	0.0	nanT	-	-	U	ko:K03290,ko:K08178,ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
IOFHDDHG_01261	6.41e-193	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX hydrolase
IOFHDDHG_01262	8.39e-196	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
IOFHDDHG_01263	2.12e-224	xerD	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	recombinase XerD
IOFHDDHG_01264	7.76e-81	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IOFHDDHG_01265	3.31e-35	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
IOFHDDHG_01266	1.86e-139	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IOFHDDHG_01267	2.3e-142	-	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamin pyrophosphokinase, vitamin B1 binding domain
IOFHDDHG_01268	4.82e-254	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IOFHDDHG_01269	8.17e-114	ybaK	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IOFHDDHG_01270	1.88e-219	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IOFHDDHG_01271	9.14e-239	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
IOFHDDHG_01272	1.25e-49	-	-	-	-	-	-	-	-
IOFHDDHG_01273	6.43e-126	sigH	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IOFHDDHG_01274	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IOFHDDHG_01275	9.52e-240	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
IOFHDDHG_01276	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
IOFHDDHG_01277	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
IOFHDDHG_01278	2.95e-123	-	-	-	F	-	-	-	NUDIX domain
IOFHDDHG_01279	0.0	-	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOFHDDHG_01280	5.18e-255	dppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_01281	2e-243	dppB	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_01282	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
IOFHDDHG_01283	3.68e-276	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
IOFHDDHG_01284	1.16e-212	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
IOFHDDHG_01285	5.88e-278	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
IOFHDDHG_01287	4.11e-314	-	-	-	G	-	-	-	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
IOFHDDHG_01288	5.61e-181	ftsQ	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
IOFHDDHG_01289	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
IOFHDDHG_01290	1.05e-273	murG	2.4.1.227, 6.3.2.8	GT28	M	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IOFHDDHG_01291	4.97e-259	ftsW	2.4.1.227	GT28	D	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	Belongs to the SEDS family
IOFHDDHG_01292	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IOFHDDHG_01293	1.38e-251	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IOFHDDHG_01294	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IOFHDDHG_01295	2.91e-198	-	-	-	M	-	-	-	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IOFHDDHG_01296	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding protein, transpeptidase domain protein
IOFHDDHG_01297	2.08e-81	-	-	-	D	-	-	-	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IOFHDDHG_01298	1.41e-242	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IOFHDDHG_01299	9.51e-119	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
IOFHDDHG_01300	0.0	-	-	-	L	-	-	-	DNA helicase
IOFHDDHG_01301	1.19e-276	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
IOFHDDHG_01302	1.01e-109	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IOFHDDHG_01303	3.61e-71	-	-	-	M	-	-	-	Lysin motif
IOFHDDHG_01304	6.88e-170	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IOFHDDHG_01305	3.34e-192	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IOFHDDHG_01306	3.25e-225	ldh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
IOFHDDHG_01307	0.0	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IOFHDDHG_01308	3.96e-144	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
IOFHDDHG_01309	0.0	hrpA	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Helicase associated domain (HA2) Add an annotation
IOFHDDHG_01310	3.33e-244	-	-	-	-	-	-	-	-
IOFHDDHG_01311	5.28e-240	-	-	-	V	-	-	-	N-Acetylmuramoyl-L-alanine amidase
IOFHDDHG_01312	9.69e-130	-	-	-	-	-	-	-	-
IOFHDDHG_01313	5.66e-72	-	-	-	T	-	-	-	helix_turn_helix, Lux Regulon
IOFHDDHG_01315	2.06e-151	-	-	-	V	ko:K02003,ko:K09810	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOFHDDHG_01316	7.41e-279	-	-	-	EGP	ko:K18567,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
IOFHDDHG_01317	1.66e-185	-	-	-	M	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
IOFHDDHG_01318	7.14e-306	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
IOFHDDHG_01319	0.0	glnA2	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
IOFHDDHG_01320	3.39e-167	hisA	5.3.1.16, 5.3.1.24	-	E	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
IOFHDDHG_01321	1.77e-156	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IOFHDDHG_01322	1.15e-163	-	-	-	-	-	-	-	-
IOFHDDHG_01323	4.56e-142	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
IOFHDDHG_01324	1.36e-287	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IOFHDDHG_01325	0.0	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IOFHDDHG_01326	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
IOFHDDHG_01327	3.52e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IOFHDDHG_01328	5.61e-121	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IOFHDDHG_01329	2.23e-65	-	-	-	V	-	-	-	DivIVA protein
IOFHDDHG_01330	9.14e-55	-	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
IOFHDDHG_01331	5.84e-105	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IOFHDDHG_01332	4.66e-279	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IOFHDDHG_01333	7.9e-312	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IOFHDDHG_01334	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
IOFHDDHG_01335	3.3e-137	-	-	-	S	ko:K02664	-	ko00000,ko02035,ko02044	Pilus assembly protein, PilO
IOFHDDHG_01336	1.14e-210	-	-	-	NU	-	-	-	PFAM Fimbrial assembly family protein
IOFHDDHG_01337	1.53e-244	pilM	-	-	NU	ko:K02662	-	ko00000,ko02035,ko02044	Type IV pilus assembly protein PilM;
IOFHDDHG_01338	1.33e-195	pppA	3.4.23.43	-	NOU	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Bacterial Peptidase A24 N-terminal domain
IOFHDDHG_01339	0.0	-	-	-	-	-	-	-	-
IOFHDDHG_01340	1.01e-292	tapC	-	-	U	ko:K02653	-	ko00000,ko02035,ko02044	Type II secretion system (T2SS), protein F
IOFHDDHG_01341	2.3e-51	-	-	-	NU	ko:K02650	ko02020,map02020	ko00000,ko00001,ko02035,ko02044	Prokaryotic N-terminal methylation motif
IOFHDDHG_01342	8.94e-135	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
IOFHDDHG_01343	5.88e-176	-	-	-	NU	ko:K02671	-	ko00000,ko02035,ko02044	Prokaryotic N-terminal methylation motif
IOFHDDHG_01344	0.0	pilB	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
IOFHDDHG_01345	0.0	pilT	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
IOFHDDHG_01346	0.0	-	-	-	-	-	-	-	-
IOFHDDHG_01347	3.83e-197	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IOFHDDHG_01348	1.58e-170	thiE	2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17	-	H	ko:K03147,ko:K14153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IOFHDDHG_01349	8.33e-192	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IOFHDDHG_01350	3.37e-79	-	-	-	S	-	-	-	Thiamine-binding protein
IOFHDDHG_01351	4.38e-245	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IOFHDDHG_01352	1.54e-307	lacY	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
IOFHDDHG_01353	0.0	fosC	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
IOFHDDHG_01354	4.99e-190	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_01355	4.1e-261	-	-	-	P	-	-	-	NMT1/THI5 like
IOFHDDHG_01356	8.03e-295	-	-	-	F	-	-	-	nucleoside hydrolase
IOFHDDHG_01357	8.46e-197	uppS	2.5.1.31, 2.5.1.86, 2.5.1.88	-	H	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IOFHDDHG_01358	4.14e-173	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
IOFHDDHG_01359	0.0	-	-	-	I	-	-	-	acetylesterase activity
IOFHDDHG_01360	5.54e-286	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IOFHDDHG_01361	1.19e-277	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
IOFHDDHG_01362	0.0	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
IOFHDDHG_01364	5.22e-276	-	-	-	L	-	-	-	Phage integrase family
IOFHDDHG_01367	2.26e-39	-	-	-	K	-	-	-	Transcriptional regulator
IOFHDDHG_01368	6.72e-68	-	-	-	-	-	-	-	-
IOFHDDHG_01369	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
IOFHDDHG_01370	0.0	abfA1	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	arabinose metabolic process
IOFHDDHG_01371	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOFHDDHG_01372	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOFHDDHG_01373	2.07e-155	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
IOFHDDHG_01374	6.44e-194	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
IOFHDDHG_01375	3.81e-107	-	-	-	S	-	-	-	SnoaL-like domain
IOFHDDHG_01376	7.76e-185	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IOFHDDHG_01377	9.75e-308	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IOFHDDHG_01378	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
IOFHDDHG_01379	8.06e-213	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_01380	5.4e-201	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_01381	3.93e-176	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	oligopeptide transport protein of the ABC superfamily, ATP-binding component
IOFHDDHG_01382	1.46e-177	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOFHDDHG_01383	2.45e-244	cbs	2.5.1.47, 4.2.1.22	-	E	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
IOFHDDHG_01384	4.68e-280	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
IOFHDDHG_01385	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOFHDDHG_01386	1.51e-232	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
IOFHDDHG_01387	8.45e-177	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
IOFHDDHG_01388	1.29e-117	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IOFHDDHG_01389	4.58e-131	cysE	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IOFHDDHG_01390	0.0	aap1	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
IOFHDDHG_01391	0.0	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IOFHDDHG_01392	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IOFHDDHG_01393	1.13e-273	-	-	-	P	-	-	-	Citrate transporter
IOFHDDHG_01395	3.1e-223	-	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
IOFHDDHG_01397	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
IOFHDDHG_01403	2.6e-131	-	-	-	K	-	-	-	acetyltransferase
IOFHDDHG_01404	2.28e-140	glnP2	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_01405	3.03e-157	glnP	-	-	E	ko:K02029,ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_01406	1.38e-191	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATP binding protein of ABC transporter for glutamate aspartate K02028
IOFHDDHG_01407	2.92e-203	glnH	-	-	ET	ko:K02030,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
IOFHDDHG_01408	3.63e-257	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IOFHDDHG_01409	7.15e-199	metQ	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
IOFHDDHG_01410	4.18e-240	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IOFHDDHG_01411	4.35e-134	-	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 9.99
IOFHDDHG_01412	3.71e-281	-	2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83	-	E	ko:K00812,ko:K08969,ko:K10206,ko:K14260,ko:K14261	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
IOFHDDHG_01413	2.19e-98	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
IOFHDDHG_01414	7.85e-59	-	-	-	O	-	-	-	Glutaredoxin
IOFHDDHG_01415	1.89e-178	hflK	-	-	O	-	-	-	prohibitin homologues
IOFHDDHG_01416	7e-99	-	-	-	-	-	-	-	-
IOFHDDHG_01417	1.97e-172	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOFHDDHG_01418	5.46e-208	-	-	-	M	-	-	-	Conserved repeat domain
IOFHDDHG_01419	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
IOFHDDHG_01420	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IOFHDDHG_01421	3.84e-233	yogA	-	-	C	-	-	-	Zinc-binding dehydrogenase
IOFHDDHG_01422	2.09e-110	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IOFHDDHG_01423	3.33e-287	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IOFHDDHG_01424	7.41e-117	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
IOFHDDHG_01425	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
IOFHDDHG_01426	1.34e-258	-	2.7.1.83	-	G	ko:K16328	ko00240,map00240	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
IOFHDDHG_01427	4.55e-242	yeiI	2.7.1.15, 2.7.1.45, 2.7.1.83	-	G	ko:K00852,ko:K00874,ko:K16328	ko00030,ko00240,ko01100,ko01120,ko01200,map00030,map00240,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
IOFHDDHG_01428	1.06e-165	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	N-(5'phosphoribosyl)anthranilate (PRA) isomerase
IOFHDDHG_01429	2.58e-274	-	-	-	C	ko:K19954	-	ko00000,ko01000	Iron-containing alcohol dehydrogenase
IOFHDDHG_01430	8.1e-236	rihB	3.2.2.1, 3.2.2.8	-	F	ko:K01239,ko:K01250,ko:K10213	ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
IOFHDDHG_01431	5.47e-314	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOFHDDHG_01432	8.42e-299	purD	6.3.3.1, 6.3.4.13	-	F	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
IOFHDDHG_01433	1.07e-242	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
IOFHDDHG_01434	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IOFHDDHG_01435	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	DNA-damage repair protein (DNA polymerase IV) K00961
IOFHDDHG_01436	3.2e-49	-	-	-	-	-	-	-	-
IOFHDDHG_01437	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
IOFHDDHG_01438	1.97e-175	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
IOFHDDHG_01439	3.48e-288	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IOFHDDHG_01440	8.83e-288	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
IOFHDDHG_01441	8.99e-254	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
IOFHDDHG_01443	1.51e-240	-	-	-	S	ko:K03453	-	ko00000	SBF-like CPA transporter family (DUF4137)
IOFHDDHG_01444	5.77e-81	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IOFHDDHG_01445	9.4e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IOFHDDHG_01446	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IOFHDDHG_01447	2.12e-295	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IOFHDDHG_01448	2.2e-134	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IOFHDDHG_01449	1.21e-98	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IOFHDDHG_01450	2.95e-305	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
IOFHDDHG_01451	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
IOFHDDHG_01452	1.42e-218	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
IOFHDDHG_01453	3.1e-138	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
IOFHDDHG_01455	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
IOFHDDHG_01456	5.45e-61	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IOFHDDHG_01457	9.67e-284	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IOFHDDHG_01458	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IOFHDDHG_01459	3.02e-173	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IOFHDDHG_01460	3.54e-229	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IOFHDDHG_01461	1.29e-158	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
IOFHDDHG_01462	0.0	arc	-	-	O	ko:K13527	ko03050,map03050	ko00000,ko00001,ko00002,ko03051	AAA ATPase forming ring-shaped complexes
IOFHDDHG_01463	0.0	dop	3.5.1.119	-	S	ko:K20814	-	ko00000,ko01000,ko03051	Pup-ligase protein
IOFHDDHG_01464	8.18e-206	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
IOFHDDHG_01465	5.14e-34	pup	-	-	S	ko:K13570	-	ko00000,ko04121	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
IOFHDDHG_01466	0.0	pafA	6.3.1.19	-	O	ko:K13571	-	ko00000,ko00002,ko01000,ko03051	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
IOFHDDHG_01467	7.66e-181	-	-	-	C	-	-	-	FMN binding
IOFHDDHG_01468	1.11e-77	-	-	-	-	-	-	-	-
IOFHDDHG_01469	4.7e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
IOFHDDHG_01470	0.0	-	-	-	S	-	-	-	Lysylphosphatidylglycerol synthase TM region
IOFHDDHG_01471	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminal
IOFHDDHG_01472	0.0	-	-	-	S	-	-	-	PGAP1-like protein
IOFHDDHG_01473	7.03e-104	-	-	-	-	-	-	-	-
IOFHDDHG_01474	5.88e-233	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
IOFHDDHG_01475	1.78e-242	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
IOFHDDHG_01476	3.29e-121	-	-	-	-	-	-	-	-
IOFHDDHG_01477	3.01e-224	-	-	-	S	-	-	-	Protein of unknown function DUF58
IOFHDDHG_01478	5.34e-233	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
IOFHDDHG_01479	9.46e-176	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IOFHDDHG_01480	1.2e-117	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
IOFHDDHG_01481	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IOFHDDHG_01482	1.74e-38	-	-	-	S	-	-	-	Proteins of 100 residues with WXG
IOFHDDHG_01483	8.75e-169	-	-	-	-	-	-	-	-
IOFHDDHG_01484	3.53e-170	phoP	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulator receiver domain protein
IOFHDDHG_01485	0.0	phoR	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
IOFHDDHG_01486	6.1e-88	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
IOFHDDHG_01487	1.23e-243	-	-	-	S	-	-	-	Protein of unknown function (DUF3027)
IOFHDDHG_01488	3.89e-242	uspA	-	-	T	-	-	-	Belongs to the universal stress protein A family
IOFHDDHG_01489	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
IOFHDDHG_01490	0.0	codA	3.5.4.1, 3.5.4.21	-	F	ko:K01485,ko:K03365	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
IOFHDDHG_01491	0.0	-	-	-	QT	-	-	-	Purine catabolism regulatory protein-like family
IOFHDDHG_01492	4.42e-315	proP	-	-	EGP	ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
IOFHDDHG_01493	1.71e-180	-	3.5.2.10	-	S	ko:K01470	ko00330,map00330	ko00000,ko00001,ko01000	Creatinine amidohydrolase
IOFHDDHG_01494	1.25e-299	-	-	-	S	-	-	-	Domain of Unknown Function (DUF349)
IOFHDDHG_01495	0.0	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
IOFHDDHG_01496	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IOFHDDHG_01497	0.0	glnP	-	-	E	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_01498	1.01e-179	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOFHDDHG_01499	3.16e-176	gluA	-	-	E	ko:K10008	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding protein of ABC transporter for glutamate K02028
IOFHDDHG_01500	1.19e-195	gluB	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
IOFHDDHG_01501	2.44e-143	gluC	-	-	E	ko:K10006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_01502	7.14e-257	gluD	-	-	E	ko:K10007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_01503	4.93e-244	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
IOFHDDHG_01504	0.0	-	-	-	L	-	-	-	DEAD DEAH box helicase
IOFHDDHG_01505	0.0	rarA	-	-	L	ko:K07478	-	ko00000	Recombination factor protein RarA
IOFHDDHG_01506	5.32e-172	mtrA	-	-	KT	ko:K07670	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
IOFHDDHG_01507	0.0	mtrB	2.7.13.3	-	T	ko:K07636,ko:K07654	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
IOFHDDHG_01508	0.0	lpqB	-	-	S	-	-	-	Lipoprotein LpqB beta-propeller domain
IOFHDDHG_01509	4.37e-219	-	-	-	G	ko:K02058,ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
IOFHDDHG_01510	0.0	-	3.6.3.17	-	G	ko:K02056,ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOFHDDHG_01511	2.87e-231	ytfT	-	-	U	ko:K02057,ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
IOFHDDHG_01512	1.77e-219	-	-	-	U	ko:K02057,ko:K10440,ko:K17209	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
IOFHDDHG_01513	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOFHDDHG_01514	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
IOFHDDHG_01515	1.25e-147	clpP1	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IOFHDDHG_01516	9.35e-161	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IOFHDDHG_01517	5.76e-308	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IOFHDDHG_01520	2.92e-315	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IOFHDDHG_01521	1.44e-150	safC	-	-	S	-	-	-	O-methyltransferase
IOFHDDHG_01522	4.82e-226	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
IOFHDDHG_01523	0.0	sdhA	1.3.5.1, 1.3.5.4, 1.4.3.16	-	C	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Succinate dehydrogenase flavoprotein subunit
IOFHDDHG_01524	0.0	dprA	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
IOFHDDHG_01525	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
IOFHDDHG_01526	1.07e-107	yraN	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
IOFHDDHG_01527	8.71e-211	pdxY	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
IOFHDDHG_01528	0.0	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Aminotransferase class-V
IOFHDDHG_01529	1.88e-124	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
IOFHDDHG_01530	0.0	ykoD	-	-	P	ko:K16784,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IOFHDDHG_01531	4.49e-192	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
IOFHDDHG_01532	9.87e-245	asnC	-	-	K	ko:K03718	-	ko00000,ko03000	helix_turn_helix ASNC type
IOFHDDHG_01533	2.47e-180	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOFHDDHG_01534	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
IOFHDDHG_01535	4.38e-162	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
IOFHDDHG_01536	0.0	-	-	-	T	-	-	-	Histidine kinase
IOFHDDHG_01537	0.0	pip	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	alpha/beta hydrolase fold
IOFHDDHG_01538	4.74e-175	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IOFHDDHG_01539	3.03e-257	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IOFHDDHG_01540	4.93e-306	-	-	-	S	-	-	-	HipA-like C-terminal domain
IOFHDDHG_01541	1.44e-22	-	-	-	K	ko:K21498	-	ko00000,ko02048	addiction module antidote protein HigA
IOFHDDHG_01542	2.32e-269	-	-	-	G	-	-	-	Transmembrane secretion effector
IOFHDDHG_01543	8.2e-152	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOFHDDHG_01544	7.94e-78	yccF	-	-	S	-	-	-	Inner membrane component domain
IOFHDDHG_01545	1.1e-16	-	-	-	-	-	-	-	-
IOFHDDHG_01548	1.78e-142	-	-	-	S	-	-	-	zinc finger
IOFHDDHG_01549	1.98e-133	-	-	-	S	-	-	-	zinc finger
IOFHDDHG_01550	8.64e-97	-	-	-	S	-	-	-	Bacterial PH domain
IOFHDDHG_01551	2.94e-99	-	-	-	-	-	-	-	-
IOFHDDHG_01552	0.0	-	-	-	KL	-	-	-	Domain of unknown function (DUF3427)
IOFHDDHG_01553	5.19e-78	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
IOFHDDHG_01554	0.0	-	3.6.4.12	-	L	ko:K03658	-	ko00000,ko01000,ko03400	Psort location Cytoplasmic, score 8.87
IOFHDDHG_01555	4.54e-241	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
IOFHDDHG_01556	2.71e-92	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
IOFHDDHG_01557	2.12e-296	aspB	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
IOFHDDHG_01558	4.54e-214	ppx1	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
IOFHDDHG_01559	9.9e-129	tmp1	-	-	S	-	-	-	Domain of unknown function (DUF4391)
IOFHDDHG_01562	1.94e-55	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
IOFHDDHG_01564	2.04e-253	-	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
IOFHDDHG_01566	8.4e-56	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IOFHDDHG_01567	2.58e-312	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IOFHDDHG_01568	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
IOFHDDHG_01569	3.18e-179	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IOFHDDHG_01570	1.02e-199	-	-	-	I	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
IOFHDDHG_01571	0.0	hgdC	-	-	I	-	-	-	CoA enzyme activase uncharacterised domain (DUF2229)
IOFHDDHG_01572	0.0	egtA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Glutamate-cysteine ligase family 2(GCS2)
IOFHDDHG_01573	6.2e-154	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOFHDDHG_01574	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Beta-galactosidase trimerisation domain
IOFHDDHG_01575	1.91e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOFHDDHG_01576	3.54e-281	-	-	-	G	-	-	-	Transporter major facilitator family protein
IOFHDDHG_01578	0.0	-	3.2.1.45	GH30	G	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 TIM-barrel domain
IOFHDDHG_01580	2.5e-24	-	-	-	Q	-	-	-	Belongs to the P-Pant transferase superfamily
IOFHDDHG_01581	3.04e-162	-	-	-	U	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
IOFHDDHG_01582	1.41e-266	-	-	-	M	-	-	-	Belongs to the D-alanine--D-alanine ligase family
IOFHDDHG_01583	2.71e-66	-	-	-	Q	-	-	-	Condensation domain
IOFHDDHG_01584	1.15e-253	-	-	-	P	-	-	-	Major Facilitator Superfamily
IOFHDDHG_01585	2.26e-312	-	3.2.1.4, 3.2.1.58	GH5,GH9	G	ko:K01179,ko:K01210	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IOFHDDHG_01586	0.0	-	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 43
IOFHDDHG_01587	1.73e-307	-	3.2.1.4, 3.2.1.58	GH5,GH9	G	ko:K01179,ko:K01210	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IOFHDDHG_01588	1.1e-139	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOFHDDHG_01589	0.0	bgl2	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
IOFHDDHG_01590	5.7e-279	-	-	-	U	ko:K08168,ko:K18926	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
IOFHDDHG_01591	2.17e-147	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein domain
IOFHDDHG_01592	3.45e-273	-	-	-	U	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
IOFHDDHG_01593	0.0	-	3.2.1.40	-	E	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase C-terminal domain
IOFHDDHG_01594	8.54e-232	-	-	-	G	-	-	-	Transporter major facilitator family protein
IOFHDDHG_01595	1.9e-239	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
IOFHDDHG_01596	1.42e-137	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOFHDDHG_01597	0.0	bglB	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
IOFHDDHG_01598	1.35e-133	-	-	-	K	-	-	-	MarR family
IOFHDDHG_01599	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
IOFHDDHG_01600	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
IOFHDDHG_01601	1.34e-232	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
IOFHDDHG_01602	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
IOFHDDHG_01603	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IOFHDDHG_01604	0.0	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	DEAD-like helicases superfamily
IOFHDDHG_01605	2.61e-177	cas5d	-	-	S	ko:K19119	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
IOFHDDHG_01606	0.0	-	-	-	M	ko:K19117	-	ko00000,ko02048	CRISPR-associated protein (Cas_Csd1)
IOFHDDHG_01607	1.69e-196	-	-	-	L	ko:K19118	-	ko00000,ko02048	CRISPR-associated protein Cas7
IOFHDDHG_01608	1.99e-167	cas4	3.1.12.1	-	L	ko:K07464,ko:K15342	-	ko00000,ko01000,ko02048,ko03400	Domain of unknown function DUF83
IOFHDDHG_01609	1.18e-250	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IOFHDDHG_01610	1.88e-62	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IOFHDDHG_01611	2.98e-153	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
IOFHDDHG_01612	2.23e-305	-	4.4.1.8	-	E	ko:K00842,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
IOFHDDHG_01613	1.25e-238	-	-	-	K	-	-	-	LysR substrate binding domain protein
IOFHDDHG_01614	2.29e-204	-	-	-	S	-	-	-	Patatin-like phospholipase
IOFHDDHG_01615	1.05e-226	iaaA	3.4.19.5	-	E	ko:K13051	-	ko00000,ko01000,ko01002	Asparaginase
IOFHDDHG_01616	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
IOFHDDHG_01617	1.5e-29	-	-	-	S	ko:K07001	-	ko00000	lipid catabolic process
IOFHDDHG_01618	1.07e-186	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
IOFHDDHG_01619	1.8e-216	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
IOFHDDHG_01620	6.1e-151	-	-	-	S	-	-	-	Vitamin K epoxide reductase
IOFHDDHG_01621	4.79e-221	PPA1328	3.1.3.97, 3.1.4.57	-	S	ko:K07053,ko:K20859	ko00440,map00440	ko00000,ko00001,ko01000	DNA polymerase alpha chain like domain
IOFHDDHG_01622	4.61e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF3107)
IOFHDDHG_01623	0.0	mphA	-	-	S	-	-	-	Aminoglycoside phosphotransferase
IOFHDDHG_01624	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
IOFHDDHG_01625	0.0	-	-	-	S	-	-	-	Zincin-like metallopeptidase
IOFHDDHG_01626	2.01e-196	sdrC	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
IOFHDDHG_01627	3.68e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3052)
IOFHDDHG_01628	5.2e-113	-	-	-	-	-	-	-	-
IOFHDDHG_01629	1.41e-164	-	-	-	-	-	-	-	-
IOFHDDHG_01630	4.1e-39	-	-	-	-	-	-	-	-
IOFHDDHG_01631	3e-60	-	-	-	-	-	-	-	-
IOFHDDHG_01637	2.22e-34	-	-	-	-	-	-	-	-
IOFHDDHG_01638	3.83e-19	-	-	-	-	-	-	-	-
IOFHDDHG_01644	1.62e-105	-	-	-	L	-	-	-	YqaJ-like viral recombinase domain
IOFHDDHG_01645	1.37e-91	-	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
IOFHDDHG_01646	1.25e-92	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
IOFHDDHG_01648	8.83e-45	-	-	-	-	-	-	-	-
IOFHDDHG_01649	8.94e-14	-	-	-	-	-	-	-	-
IOFHDDHG_01651	8.07e-51	-	-	-	-	-	-	-	-
IOFHDDHG_01655	1.07e-171	-	-	-	-	-	-	-	-
IOFHDDHG_01656	1.88e-40	-	-	-	S	-	-	-	Protein of unknwon function (DUF3310)
IOFHDDHG_01658	1.47e-24	-	-	-	-	-	-	-	-
IOFHDDHG_01659	1.01e-173	-	-	-	-	-	-	-	-
IOFHDDHG_01661	7.1e-83	-	-	-	-	-	-	-	-
IOFHDDHG_01662	0.0	-	-	-	S	-	-	-	Terminase
IOFHDDHG_01663	2.05e-202	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
IOFHDDHG_01664	1.45e-60	-	-	-	-	-	-	-	-
IOFHDDHG_01666	1.58e-151	-	-	-	-	-	-	-	-
IOFHDDHG_01667	0.000149	-	-	-	-	-	-	-	-
IOFHDDHG_01670	4.27e-70	-	-	-	-	-	-	-	-
IOFHDDHG_01671	1.9e-60	-	-	-	-	-	-	-	-
IOFHDDHG_01672	9.83e-87	-	-	-	-	-	-	-	-
IOFHDDHG_01673	2.23e-113	-	-	-	-	-	-	-	-
IOFHDDHG_01674	2.61e-106	-	-	-	-	-	-	-	-
IOFHDDHG_01676	0.0	-	-	-	S	-	-	-	Phage-related minor tail protein
IOFHDDHG_01677	5.39e-190	-	-	-	-	-	-	-	-
IOFHDDHG_01678	1.4e-311	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
IOFHDDHG_01680	9.22e-108	-	-	-	-	-	-	-	-
IOFHDDHG_01683	8.09e-32	-	-	-	-	-	-	-	-
IOFHDDHG_01684	1.56e-47	-	-	-	-	-	-	-	-
IOFHDDHG_01685	5.28e-184	-	-	-	L	-	-	-	DNA integration
IOFHDDHG_01687	7.64e-215	-	-	-	-	-	-	-	-
IOFHDDHG_01688	4.82e-121	-	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	reverse transcriptase
IOFHDDHG_01691	5.85e-28	-	-	-	-	-	-	-	-
IOFHDDHG_01693	1.04e-94	-	-	-	V	-	-	-	Ami_2
IOFHDDHG_01694	4.42e-21	-	-	-	-	-	-	-	-
IOFHDDHG_01695	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
IOFHDDHG_01696	6.67e-158	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IOFHDDHG_01697	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IOFHDDHG_01698	0.0	pepN	3.4.11.2	-	E	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Peptidase family M1 domain
IOFHDDHG_01699	0.0	rnj	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IOFHDDHG_01700	4.1e-223	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IOFHDDHG_01701	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
IOFHDDHG_01702	1.32e-49	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
IOFHDDHG_01703	4.54e-171	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IOFHDDHG_01704	3.41e-275	-	-	-	G	-	-	-	Major Facilitator Superfamily
IOFHDDHG_01705	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	Belongs to the helicase family. UvrD subfamily
IOFHDDHG_01706	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
IOFHDDHG_01707	0.0	pknK	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
IOFHDDHG_01708	0.0	-	-	-	S	-	-	-	Fibronectin type 3 domain
IOFHDDHG_01709	1.28e-300	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
IOFHDDHG_01710	2.7e-281	-	-	-	S	-	-	-	Protein of unknown function DUF58
IOFHDDHG_01711	0.0	-	-	-	E	-	-	-	Transglutaminase-like superfamily
IOFHDDHG_01712	7.29e-107	-	-	-	B	-	-	-	Belongs to the OprB family
IOFHDDHG_01713	4.6e-123	-	-	-	T	-	-	-	Forkhead associated domain
IOFHDDHG_01714	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOFHDDHG_01715	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOFHDDHG_01716	1.98e-137	-	-	-	-	-	-	-	-
IOFHDDHG_01717	4.39e-224	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	FES
IOFHDDHG_01718	4.51e-162	spoU	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IOFHDDHG_01719	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
IOFHDDHG_01720	1.32e-57	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
IOFHDDHG_01721	0.0	-	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
IOFHDDHG_01722	1.99e-227	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IOFHDDHG_01723	2.77e-149	-	-	-	S	-	-	-	Protein of unknown function, DUF624
IOFHDDHG_01724	5.56e-217	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_01725	1.49e-227	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_01726	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOFHDDHG_01727	1.19e-296	galK	2.7.1.6, 2.7.7.12	-	G	ko:K00849,ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
IOFHDDHG_01728	9.99e-317	galT	2.7.7.12	-	C	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, N-terminal domain
IOFHDDHG_01729	1.13e-181	-	-	-	K	-	-	-	DeoR C terminal sensor domain
IOFHDDHG_01730	1.65e-288	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
IOFHDDHG_01731	1.94e-269	namA	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
IOFHDDHG_01732	0.0	pon1	-	-	M	-	-	-	Transglycosylase
IOFHDDHG_01733	3.02e-170	crp	-	-	K	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
IOFHDDHG_01734	6.07e-274	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
IOFHDDHG_01735	1.32e-135	-	-	-	J	-	-	-	TM2 domain
IOFHDDHG_01736	3.92e-246	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IOFHDDHG_01737	0.0	ptrB	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Peptidase, S9A B C family, catalytic domain protein
IOFHDDHG_01738	3.06e-301	-	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2183)
IOFHDDHG_01739	1.36e-91	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
IOFHDDHG_01740	5.11e-266	nudC	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
IOFHDDHG_01741	4.55e-206	-	-	-	I	-	-	-	Alpha/beta hydrolase family
IOFHDDHG_01742	2.77e-147	-	-	-	F	-	-	-	Domain of unknown function (DUF4916)
IOFHDDHG_01743	3.24e-77	trxA	1.8.1.9	-	O	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	ko00000,ko00001,ko01000,ko03110	Belongs to the thioredoxin family
IOFHDDHG_01744	1.25e-219	-	-	-	S	ko:K21688	-	ko00000	G5
IOFHDDHG_01745	4.23e-115	-	-	-	-	-	-	-	-
IOFHDDHG_01746	3.3e-94	-	-	-	-	-	-	-	-
IOFHDDHG_01747	4.77e-38	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
IOFHDDHG_01748	6.84e-97	-	-	-	-	-	-	-	-
IOFHDDHG_01749	3.16e-125	etp	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
IOFHDDHG_01750	0.0	wcoI	-	-	DM	-	-	-	Psort location CytoplasmicMembrane, score
IOFHDDHG_01751	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
IOFHDDHG_01752	5.43e-189	-	-	-	P	ko:K02026,ko:K10190	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_01753	2.74e-209	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_01754	1.01e-284	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOFHDDHG_01755	7.45e-42	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOFHDDHG_01756	1.15e-234	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
IOFHDDHG_01757	1.8e-74	yccF	-	-	S	-	-	-	Inner membrane component domain
IOFHDDHG_01758	1.36e-144	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
IOFHDDHG_01759	3.44e-157	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
IOFHDDHG_01760	3.22e-104	-	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
IOFHDDHG_01761	3.39e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF4065)
IOFHDDHG_01762	4.7e-69	-	-	-	S	-	-	-	Protein of unknown function (DUF4065)
IOFHDDHG_01763	1.17e-82	-	-	-	-	-	-	-	-
IOFHDDHG_01764	2.18e-153	-	-	-	V	-	-	-	Abi-like protein
IOFHDDHG_01765	2.59e-14	-	-	-	L	-	-	-	DNA-dependent DNA replication
IOFHDDHG_01770	2.44e-155	-	-	-	S	-	-	-	polysaccharide biosynthetic process
IOFHDDHG_01771	4.72e-167	-	-	-	GM	ko:K19431	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
IOFHDDHG_01772	3.27e-117	-	2.7.8.12	-	S	ko:K09809	-	ko00000,ko01000	Glycosyltransferase like family 2
IOFHDDHG_01773	9.03e-38	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
IOFHDDHG_01774	3.58e-115	-	-	-	-	-	-	-	-
IOFHDDHG_01776	2.54e-172	-	2.7.8.12	GT2	S	ko:K09809,ko:K19427	-	ko00000,ko01000	Glycosyltransferase like family 2
IOFHDDHG_01777	1.09e-263	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
IOFHDDHG_01778	1.05e-273	-	-	-	M	-	-	-	Domain of unknown function (DUF1972)
IOFHDDHG_01779	3.41e-172	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
IOFHDDHG_01781	2.29e-245	-	2.7.8.12	-	S	ko:K09809	-	ko00000,ko01000	Glycosyltransferase like family 2
IOFHDDHG_01782	2.26e-267	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
IOFHDDHG_01783	4.72e-240	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.87
IOFHDDHG_01784	6.35e-278	rfbX	-	-	S	ko:K03328,ko:K18799	-	ko00000,ko01005,ko02000	polysaccharide biosynthetic process
IOFHDDHG_01785	8.38e-30	-	-	-	G	-	-	-	Acyltransferase family
IOFHDDHG_01786	3.88e-140	-	-	-	G	-	-	-	Acyltransferase family
IOFHDDHG_01787	1.47e-112	-	-	-	L	-	-	-	PFAM Integrase catalytic
IOFHDDHG_01788	2.16e-16	-	-	-	S	-	-	-	YjzC-like protein
IOFHDDHG_01789	4.02e-185	-	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
IOFHDDHG_01790	0.0	-	-	-	O	-	-	-	Subtilase family
IOFHDDHG_01791	1.63e-49	-	-	-	V	-	-	-	Abi-like protein
IOFHDDHG_01792	1.83e-244	-	-	-	-	-	-	-	-
IOFHDDHG_01793	0.0	-	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
IOFHDDHG_01794	0.0	-	-	-	H	-	-	-	Protein of unknown function (DUF4012)
IOFHDDHG_01795	3.2e-241	staP	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
IOFHDDHG_01796	2.52e-63	-	-	-	-	-	-	-	-
IOFHDDHG_01797	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
IOFHDDHG_01798	3.78e-279	-	-	-	T	-	-	-	Diguanylate cyclase (GGDEF) domain protein
IOFHDDHG_01799	2.41e-169	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
IOFHDDHG_01800	3.62e-213	-	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
IOFHDDHG_01801	5.4e-309	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
IOFHDDHG_01802	8.33e-254	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
IOFHDDHG_01803	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
IOFHDDHG_01804	3.46e-41	yuxJ	-	-	EGP	-	-	-	Major facilitator Superfamily
IOFHDDHG_01805	2.4e-61	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOFHDDHG_01806	1.4e-135	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOFHDDHG_01808	1.08e-76	-	-	-	-	-	-	-	-
IOFHDDHG_01809	0.0	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
IOFHDDHG_01811	2.94e-104	-	-	-	-	-	-	-	-
IOFHDDHG_01812	0.0	-	-	-	S	ko:K07133	-	ko00000	AAA domain
IOFHDDHG_01813	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
IOFHDDHG_01814	2.4e-206	-	-	-	M	-	-	-	Glycosyl transferase family 2
IOFHDDHG_01815	4.31e-23	-	-	-	E	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
IOFHDDHG_01816	1.55e-211	-	-	-	S	-	-	-	Acyltransferase family
IOFHDDHG_01817	0.0	-	-	-	-	-	-	-	-
IOFHDDHG_01818	0.0	-	-	-	M	-	-	-	Glycosyl transferase family 8
IOFHDDHG_01819	1.1e-174	-	-	-	M	-	-	-	Glycosyl transferase, family 2
IOFHDDHG_01820	2.29e-63	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
IOFHDDHG_01821	1.53e-212	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
IOFHDDHG_01822	0.0	-	-	-	M	-	-	-	Glycosyl transferase family 8
IOFHDDHG_01823	2.5e-162	tagG	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
IOFHDDHG_01824	1.09e-276	-	-	-	GM	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOFHDDHG_01825	6.17e-178	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 43 family
IOFHDDHG_01826	6.26e-259	ugd	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP binding domain
IOFHDDHG_01827	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
IOFHDDHG_01828	1.97e-257	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IOFHDDHG_01829	2.72e-84	-	-	-	-	-	-	-	-
IOFHDDHG_01830	3.02e-253	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IOFHDDHG_01831	2.25e-215	iunH2	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
IOFHDDHG_01832	0.0	-	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
IOFHDDHG_01833	3.94e-224	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IOFHDDHG_01834	5.12e-242	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IOFHDDHG_01835	7.12e-62	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
IOFHDDHG_01836	3.6e-103	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
IOFHDDHG_01837	3.05e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IOFHDDHG_01838	1.16e-92	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
IOFHDDHG_01840	1.51e-175	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
IOFHDDHG_01841	1.28e-113	-	-	-	M	-	-	-	Protein of unknown function (DUF3152)
IOFHDDHG_01842	2.21e-267	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IOFHDDHG_01843	1.34e-103	-	-	-	-	-	-	-	-
IOFHDDHG_01844	2.91e-189	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IOFHDDHG_01845	2.75e-209	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
IOFHDDHG_01846	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IOFHDDHG_01847	5.05e-184	-	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	Heavy metal translocating P-type atpase
IOFHDDHG_01848	2.8e-261	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
IOFHDDHG_01849	8.52e-135	pyrE1	-	-	F	-	-	-	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IOFHDDHG_01850	7.3e-168	trmH	2.1.1.34	-	J	ko:K00556	-	ko00000,ko01000,ko03016	RNA methyltransferase TrmH family
IOFHDDHG_01851	1.46e-167	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
IOFHDDHG_01852	7.81e-62	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IOFHDDHG_01853	0.0	gatA	6.3.5.6, 6.3.5.7	-	F	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IOFHDDHG_01854	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IOFHDDHG_01855	1.4e-261	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IOFHDDHG_01856	1.43e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF2469)
IOFHDDHG_01857	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
IOFHDDHG_01858	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IOFHDDHG_01859	1.09e-104	lrp_3	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	helix_turn_helix ASNC type
IOFHDDHG_01860	6.95e-91	tyrA	5.4.99.5	-	E	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
IOFHDDHG_01861	0.0	-	-	-	S	-	-	-	domain protein
IOFHDDHG_01862	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IOFHDDHG_01863	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
IOFHDDHG_01864	9.55e-158	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IOFHDDHG_01865	6.39e-172	glnR	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
IOFHDDHG_01866	1.09e-173	-	-	-	-	-	-	-	-
IOFHDDHG_01867	1.22e-127	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
IOFHDDHG_01868	6.53e-118	ppa	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IOFHDDHG_01869	0.0	glgE	2.4.99.16	GH13	G	ko:K16147	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
IOFHDDHG_01870	1.05e-221	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
IOFHDDHG_01871	0.0	oxc	4.1.1.8	-	EH	ko:K01577	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Thiamine pyrophosphate enzyme, central domain
IOFHDDHG_01872	4.96e-249	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
IOFHDDHG_01873	0.0	frc	2.8.3.15, 2.8.3.16	-	C	ko:K07544,ko:K07749	ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
IOFHDDHG_01874	1.51e-113	-	-	-	L	-	-	-	Phage integrase family
IOFHDDHG_01875	1.5e-13	xhlB	-	-	S	-	-	-	SPP1 phage holin
IOFHDDHG_01876	1.6e-94	-	-	-	V	-	-	-	N-acetylmuramoyl-L-alanine amidase
IOFHDDHG_01877	2.82e-24	-	-	-	-	-	-	-	-
IOFHDDHG_01880	3.12e-257	-	-	-	NT	-	-	-	phage tail tape measure protein
IOFHDDHG_01881	9.33e-49	-	-	-	-	-	-	-	-
IOFHDDHG_01882	3.49e-72	-	-	-	-	-	-	-	-
IOFHDDHG_01883	1.5e-76	-	-	-	-	-	-	-	-
IOFHDDHG_01884	1.13e-47	-	-	-	-	-	-	-	-
IOFHDDHG_01885	2.21e-56	-	-	-	-	-	-	-	-
IOFHDDHG_01886	1.25e-267	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
IOFHDDHG_01887	5.22e-203	-	-	-	S	-	-	-	Phage portal protein
IOFHDDHG_01888	5.59e-298	-	-	-	S	-	-	-	Terminase
IOFHDDHG_01889	4.39e-53	-	-	-	-	-	-	-	-
IOFHDDHG_01890	4.81e-121	-	-	-	L	-	-	-	HNH endonuclease
IOFHDDHG_01893	7.55e-19	-	-	-	-	-	-	-	-
IOFHDDHG_01894	2.65e-34	-	-	-	-	-	-	-	-
IOFHDDHG_01899	1.21e-13	-	-	-	K	-	-	-	BetR domain
IOFHDDHG_01901	1.2e-264	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IOFHDDHG_01902	1.14e-188	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
IOFHDDHG_01903	9.64e-42	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IOFHDDHG_01904	6.4e-93	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IOFHDDHG_01905	2.31e-191	atpH	-	-	C	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IOFHDDHG_01906	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IOFHDDHG_01907	5.5e-210	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IOFHDDHG_01908	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IOFHDDHG_01909	2.85e-60	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
IOFHDDHG_01910	1.32e-156	nucS	-	-	L	ko:K07503	-	ko00000,ko01000	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
IOFHDDHG_01911	2.27e-192	-	5.2.1.8	-	M	ko:K01802	-	ko00000,ko01000	FKBP-type peptidyl-prolyl cis-trans isomerase
IOFHDDHG_01912	5.08e-265	-	-	-	-	-	-	-	-
IOFHDDHG_01913	1.98e-232	-	-	-	-	-	-	-	-
IOFHDDHG_01914	3.07e-215	ybbN	-	-	O	ko:K05838	-	ko00000,ko03110	Tetratricopeptide repeat
IOFHDDHG_01915	1.41e-156	-	-	-	S	-	-	-	CYTH
IOFHDDHG_01917	1.62e-83	psp1	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	Endoribonuclease L-PSP
IOFHDDHG_01918	0.0	-	-	-	E	ko:K16235	-	ko00000,ko02000	amino acid
IOFHDDHG_01919	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
IOFHDDHG_01920	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IOFHDDHG_01921	1.13e-305	hom	1.1.1.3, 2.7.2.4	-	E	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
IOFHDDHG_01922	5.07e-236	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IOFHDDHG_01923	0.0	maf	-	-	DF	ko:K06287	-	ko00000	Maf-like protein
IOFHDDHG_01924	6.03e-270	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
IOFHDDHG_01925	0.0	araB	-	-	G	-	-	-	FGGY family of carbohydrate kinases, C-terminal domain
IOFHDDHG_01926	1.1e-167	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Class II Aldolase and Adducin N-terminal domain
IOFHDDHG_01927	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
IOFHDDHG_01928	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
IOFHDDHG_01929	0.0	-	-	-	V	ko:K06147,ko:K06148,ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter transmembrane region
IOFHDDHG_01930	6.62e-199	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IOFHDDHG_01931	8.19e-162	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IOFHDDHG_01932	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOFHDDHG_01933	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
IOFHDDHG_01934	9.33e-309	-	-	-	V	-	-	-	ABC transporter permease
IOFHDDHG_01935	2.29e-236	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IOFHDDHG_01936	7.79e-193	-	-	-	T	ko:K06950	-	ko00000	HD domain
IOFHDDHG_01937	1.17e-214	-	-	-	S	-	-	-	Glutamine amidotransferase domain
IOFHDDHG_01938	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
IOFHDDHG_01939	3.43e-235	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
IOFHDDHG_01940	0.0	-	-	-	G	-	-	-	Alpha-L-arabinofuranosidase C-terminus
IOFHDDHG_01941	1.08e-292	-	-	-	G	-	-	-	Alpha galactosidase A
IOFHDDHG_01942	6.55e-291	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
IOFHDDHG_01943	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
IOFHDDHG_01944	6.8e-162	-	-	-	-	-	-	-	-
IOFHDDHG_01945	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IOFHDDHG_01946	5.7e-233	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IOFHDDHG_01947	0.0	fusA2	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IOFHDDHG_01948	1.19e-174	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IOFHDDHG_01949	2.82e-260	-	-	-	I	-	-	-	Hydrolase, alpha beta domain protein
IOFHDDHG_01950	2.46e-190	-	-	-	S	-	-	-	AAA domain
IOFHDDHG_01951	2.76e-182	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IOFHDDHG_01952	4.59e-298	-	-	-	M	-	-	-	Protein of unknown function (DUF2961)
IOFHDDHG_01953	0.0	-	-	-	M	-	-	-	probably involved in cell wall
IOFHDDHG_01954	0.0	-	3.2.1.14	GH18	S	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Carbohydrate binding domain
IOFHDDHG_01955	0.0	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
IOFHDDHG_01956	3.99e-239	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
IOFHDDHG_01957	3.36e-295	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
IOFHDDHG_01958	9.06e-191	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IOFHDDHG_01959	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
IOFHDDHG_01960	1.37e-221	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
IOFHDDHG_01961	1.13e-220	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
IOFHDDHG_01962	7.7e-196	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_01963	2.49e-303	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOFHDDHG_01964	6.75e-268	-	-	-	GK	-	-	-	ROK family
IOFHDDHG_01965	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
IOFHDDHG_01966	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
IOFHDDHG_01967	1.99e-175	-	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP)
IOFHDDHG_01969	0.0	lacZ3	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
IOFHDDHG_01970	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IOFHDDHG_01971	3.24e-138	-	-	-	-	-	-	-	-
IOFHDDHG_01972	1.04e-245	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IOFHDDHG_01973	1.37e-22	-	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Glycosyl hydrolase family 26
IOFHDDHG_01974	1.1e-161	dedA1	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
IOFHDDHG_01976	1.69e-166	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
IOFHDDHG_01977	6.08e-63	-	-	-	-	-	-	-	-
IOFHDDHG_01978	1.32e-145	hspR	-	-	K	ko:K13640	-	ko00000,ko03000	transcriptional regulator, MerR family
IOFHDDHG_01979	1.14e-232	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	DnaJ molecular chaperone homology domain
IOFHDDHG_01980	4.05e-107	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IOFHDDHG_01981	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
IOFHDDHG_01982	5.66e-187	-	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
IOFHDDHG_01983	2.48e-152	strK	3.1.3.1, 3.1.3.39	-	P	ko:K01077,ko:K04342	ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
IOFHDDHG_01984	7.41e-177	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IOFHDDHG_01985	4.02e-115	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
IOFHDDHG_01986	2.17e-46	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
IOFHDDHG_01987	3.91e-244	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
IOFHDDHG_01988	7.21e-179	traX	-	-	S	-	-	-	TraX protein
IOFHDDHG_01989	8.69e-186	-	-	-	S	ko:K07025	-	ko00000	HAD-hyrolase-like
IOFHDDHG_01990	0.0	apuB	3.2.1.41, 3.2.1.68	CBM48,GH13	G	ko:K01200,ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
IOFHDDHG_01991	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
IOFHDDHG_01992	3.22e-18	-	-	-	S	-	-	-	Transposon-encoded protein TnpV
IOFHDDHG_01993	1.16e-140	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Peptidase family S51
IOFHDDHG_01994	1.21e-137	-	-	-	S	-	-	-	Protein of unknown function, DUF624
IOFHDDHG_01995	8.69e-194	-	-	-	G	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IOFHDDHG_01996	2.23e-198	msmF	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_01997	1.39e-234	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
IOFHDDHG_01998	1.2e-238	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
IOFHDDHG_01999	0.0	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOFHDDHG_02000	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
IOFHDDHG_02001	0.0	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOFHDDHG_02002	1.4e-176	gpm2	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
IOFHDDHG_02003	4.34e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF4235)
IOFHDDHG_02004	1.1e-181	nfrA	-	-	C	-	-	-	Nitroreductase family
IOFHDDHG_02005	3.31e-108	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
IOFHDDHG_02006	0.0	pacL2	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
IOFHDDHG_02007	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
IOFHDDHG_02008	7.84e-192	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
IOFHDDHG_02009	1.7e-41	-	-	-	K	ko:K02538,ko:K03483,ko:K03491	-	ko00000,ko03000	PRD domain
IOFHDDHG_02010	6.49e-19	-	-	-	S	-	-	-	Psort location Extracellular, score 8.82
IOFHDDHG_02011	4.75e-295	-	-	-	EGP	-	-	-	Transmembrane secretion effector
IOFHDDHG_02012	1.48e-223	rlmB	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IOFHDDHG_02013	0.0	-	-	-	KLT	-	-	-	Domain of unknown function (DUF4032)
IOFHDDHG_02014	1.26e-268	ugpC	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOFHDDHG_02015	4.34e-169	-	-	-	K	-	-	-	LytTr DNA-binding domain
IOFHDDHG_02016	2.79e-316	-	-	-	T	-	-	-	GHKL domain
IOFHDDHG_02017	4.14e-137	-	-	-	-	-	-	-	-
IOFHDDHG_02018	2.29e-271	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
IOFHDDHG_02019	2.72e-63	-	-	-	S	ko:K07133	-	ko00000	Psort location Cytoplasmic, score
IOFHDDHG_02020	7.66e-179	-	-	-	-	-	-	-	-
IOFHDDHG_02021	9.13e-190	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
IOFHDDHG_02022	2.05e-299	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
IOFHDDHG_02023	0.0	-	-	-	S	-	-	-	LPXTG-motif cell wall anchor domain protein
IOFHDDHG_02025	7.9e-130	-	-	-	S	-	-	-	GtrA-like protein
IOFHDDHG_02026	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
IOFHDDHG_02028	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
IOFHDDHG_02029	0.0	-	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
IOFHDDHG_02030	1.34e-100	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
IOFHDDHG_02031	1.4e-109	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOFHDDHG_02032	1.87e-105	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOFHDDHG_02033	8.28e-162	msmF	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFHDDHG_02034	2.41e-151	-	-	-	G	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IOFHDDHG_02035	5.85e-33	-	-	-	S	-	-	-	Protein of unknown function, DUF624
IOFHDDHG_02036	3.57e-113	-	-	-	L	-	-	-	transposase activity
IOFHDDHG_02037	4.81e-146	-	-	-	L	-	-	-	PFAM Integrase catalytic
IOFHDDHG_02038	1.59e-152	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Psort location CytoplasmicMembrane, score
IOFHDDHG_02039	1e-103	ypeA	2.3.1.1	-	K	ko:K22477	ko00220,ko01210,ko01230,map00220,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
IOFHDDHG_02041	6.15e-146	vex	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOFHDDHG_02042	1.66e-271	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
IOFHDDHG_02043	1.27e-303	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
IOFHDDHG_02044	2.1e-101	-	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
IOFHDDHG_02045	6.03e-52	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
IOFHDDHG_02046	3.46e-18	-	-	-	S	-	-	-	Psort location Extracellular, score 8.82
IOFHDDHG_02047	6.69e-55	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
IOFHDDHG_02048	2.22e-295	-	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
IOFHDDHG_02049	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
IOFHDDHG_02050	1.22e-138	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin