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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HHFOALAE_00001	6.13e-315	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HHFOALAE_00002	1.46e-101	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HHFOALAE_00003	3.96e-254	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HHFOALAE_00004	1.89e-253	XK27_07735	-	-	S	-	-	-	YjbR
HHFOALAE_00005	9.07e-234	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	Catabolite control protein A
HHFOALAE_00006	2.55e-247	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Belongs to the peptidase M24B family
HHFOALAE_00007	1.17e-84	yugI	-	-	J	ko:K07570	-	ko00000	RNA binding protein, contains ribosomal protein S1 domain
HHFOALAE_00008	0.0	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HHFOALAE_00009	1.98e-105	smpB	-	-	O	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HHFOALAE_00010	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HHFOALAE_00011	1.06e-44	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
HHFOALAE_00012	4.18e-281	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	Major Facilitator
HHFOALAE_00013	4.17e-128	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HHFOALAE_00014	1.19e-192	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HHFOALAE_00015	3.34e-212	era	-	-	M	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HHFOALAE_00016	1.72e-85	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HHFOALAE_00017	1.31e-113	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HHFOALAE_00018	1.14e-191	licT	-	-	K	ko:K03488	-	ko00000,ko03000	antiterminator
HHFOALAE_00019	1.85e-136	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HHFOALAE_00020	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein
HHFOALAE_00021	1.61e-188	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HHFOALAE_00022	1.72e-201	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HHFOALAE_00023	6.43e-194	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HHFOALAE_00024	2.42e-12	-	-	-	-	-	-	-	-
HHFOALAE_00025	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HHFOALAE_00026	3.52e-101	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain protein
HHFOALAE_00027	2.57e-168	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
HHFOALAE_00028	2.2e-151	-	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHFOALAE_00029	3.31e-47	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
HHFOALAE_00030	2.5e-232	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HHFOALAE_00031	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HHFOALAE_00032	1.3e-109	XK27_09440	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HHFOALAE_00033	2.23e-65	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
HHFOALAE_00034	1.04e-221	-	-	-	S	-	-	-	oxidoreductase
HHFOALAE_00035	2.47e-291	murN	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	FemAB family
HHFOALAE_00036	2.37e-151	-	-	-	M	-	-	-	Pfam SNARE associated Golgi protein
HHFOALAE_00037	3.56e-138	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3862)
HHFOALAE_00040	9.51e-268	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein S1
HHFOALAE_00043	1.2e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HHFOALAE_00044	7.97e-252	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HHFOALAE_00045	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HHFOALAE_00046	1.08e-160	lyrA	-	-	S	-	-	-	CAAX amino terminal protease family protein
HHFOALAE_00047	3.56e-159	aadK	-	-	H	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
HHFOALAE_00048	1.02e-121	ykkB	-	-	J	-	-	-	GNAT family acetyltransferase
HHFOALAE_00049	1.71e-61	-	-	-	-	-	-	-	-
HHFOALAE_00050	9e-192	-	-	-	-	-	-	-	-
HHFOALAE_00051	5.9e-229	-	-	-	U	-	-	-	Protein of unknown function DUF262
HHFOALAE_00052	1.29e-93	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HHFOALAE_00055	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HHFOALAE_00056	1.81e-139	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HHFOALAE_00057	1.74e-18	-	-	-	L	-	-	-	Helix-hairpin-helix DNA-binding motif class 1
HHFOALAE_00058	3.14e-42	-	-	-	S	-	-	-	Domain of unknown function (DUF1912)
HHFOALAE_00059	8.19e-217	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	Homocysteine
HHFOALAE_00060	0.0	lysP	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HHFOALAE_00061	9.58e-144	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HHFOALAE_00062	8.89e-288	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HHFOALAE_00063	2.97e-30	-	-	-	-	-	-	-	-
HHFOALAE_00064	3.16e-116	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HHFOALAE_00065	4.23e-213	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HHFOALAE_00066	3.79e-272	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	synthase
HHFOALAE_00067	9.56e-286	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HHFOALAE_00068	1.08e-102	-	-	-	K	-	-	-	hmm pf08876
HHFOALAE_00069	3.52e-152	hly-III	-	-	K	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
HHFOALAE_00070	1.64e-39	pspC	-	-	KT	-	-	-	PspC domain protein
HHFOALAE_00071	6.62e-257	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
HHFOALAE_00072	7.23e-208	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HHFOALAE_00073	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HHFOALAE_00075	0.0	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HHFOALAE_00076	2.97e-243	dgs	2.4.1.208	GT4	M	ko:K13677	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HHFOALAE_00077	0.0	-	-	-	M	ko:K02460	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	domain protein
HHFOALAE_00078	1.73e-150	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HHFOALAE_00079	4.4e-43	-	-	-	-	-	-	-	-
HHFOALAE_00080	8.64e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	AdP-ribose pyrophosphatase
HHFOALAE_00081	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HHFOALAE_00082	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
HHFOALAE_00083	5.07e-236	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HHFOALAE_00085	6.14e-215	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HHFOALAE_00086	3.33e-215	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HHFOALAE_00087	4.62e-195	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HHFOALAE_00088	1.42e-315	merA	-	-	C	-	-	-	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HHFOALAE_00089	5.78e-176	-	-	-	E	-	-	-	Alpha beta hydrolase
HHFOALAE_00092	9e-255	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
HHFOALAE_00093	1e-272	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HHFOALAE_00094	1.27e-177	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HHFOALAE_00095	5.36e-148	-	-	-	S	-	-	-	VIT family
HHFOALAE_00097	1.61e-40	XK27_00085	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
HHFOALAE_00098	9.64e-251	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
HHFOALAE_00099	6.98e-155	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HHFOALAE_00100	2.63e-211	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HHFOALAE_00101	9.39e-167	rr02	-	-	KT	-	-	-	response regulator
HHFOALAE_00102	2.89e-291	hk02	-	-	T	-	-	-	signal transduction protein with a C-terminal ATPase domain
HHFOALAE_00103	3.97e-162	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HHFOALAE_00104	4.12e-253	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HHFOALAE_00105	0.0	lmrA	-	-	V	ko:K06147,ko:K18888	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
HHFOALAE_00106	0.0	msbA_1	-	-	V	ko:K18887	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
HHFOALAE_00107	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
HHFOALAE_00108	1.4e-134	-	-	-	K	-	-	-	Transcriptional regulator, AbiEi antitoxin
HHFOALAE_00109	4.43e-37	XK27_00530	-	-	M	-	-	-	CHAP domain protein
HHFOALAE_00110	3.41e-30	-	-	-	S	ko:K19165	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HHFOALAE_00112	6.82e-170	-	-	-	KT	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Response regulator of the LytR AlgR family
HHFOALAE_00113	5.02e-294	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HHFOALAE_00116	6.49e-65	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HHFOALAE_00117	1.7e-101	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HHFOALAE_00118	1.13e-271	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	permease protein
HHFOALAE_00119	3.24e-157	salX	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HHFOALAE_00120	2.96e-247	-	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HHFOALAE_00121	1.5e-157	-	-	-	J	-	-	-	Putative SAM-dependent methyltransferase
HHFOALAE_00122	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	carbamoyl-phosphate synthetase ammonia chain
HHFOALAE_00123	1.31e-268	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	carbamoyl-phosphate synthetase glutamine chain
HHFOALAE_00124	3.93e-220	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HHFOALAE_00125	5.51e-279	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	uracil Permease
HHFOALAE_00126	1.45e-114	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HHFOALAE_00127	2.52e-208	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HHFOALAE_00128	1.34e-98	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HHFOALAE_00129	6.02e-216	lysR	-	-	K	-	-	-	transcriptional regulator (lysR family)
HHFOALAE_00131	2.55e-88	-	-	-	K	-	-	-	Helix-turn-helix
HHFOALAE_00134	3.03e-180	ppiA	5.2.1.8	-	O	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HHFOALAE_00135	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
HHFOALAE_00137	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	permease
HHFOALAE_00138	1.17e-51	ynzC	-	-	S	-	-	-	UPF0291 protein
HHFOALAE_00139	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HHFOALAE_00140	1.23e-226	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HHFOALAE_00141	6.18e-282	-	-	-	S	-	-	-	membrane
HHFOALAE_00142	6.01e-272	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HHFOALAE_00143	0.0	yjbB	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
HHFOALAE_00144	1.54e-161	-	3.4.17.14, 3.5.1.28	-	NU	ko:K01448,ko:K02395,ko:K07260	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036	amidase activity
HHFOALAE_00145	1.59e-104	-	-	-	S	-	-	-	Bacterial inner membrane protein
HHFOALAE_00146	4.95e-186	XK27_04800	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HHFOALAE_00147	3.77e-139	mur1	3.4.17.14, 3.5.1.28	-	NU	ko:K01448,ko:K02395,ko:K07260	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036	amidase activity
HHFOALAE_00148	1.86e-70	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
HHFOALAE_00149	2.03e-290	amt	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium Transporter
HHFOALAE_00150	4.69e-202	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HHFOALAE_00151	2e-73	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HHFOALAE_00152	1.36e-175	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
HHFOALAE_00153	3.06e-204	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	dna polymerase iii
HHFOALAE_00154	9.41e-140	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HHFOALAE_00156	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HHFOALAE_00157	3.13e-173	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HHFOALAE_00158	6.46e-285	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HHFOALAE_00159	3.53e-278	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HHFOALAE_00160	1.24e-89	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HHFOALAE_00161	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HHFOALAE_00162	9.08e-202	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HHFOALAE_00163	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HHFOALAE_00164	8.62e-114	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HHFOALAE_00165	1.78e-102	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HHFOALAE_00166	8.24e-156	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HHFOALAE_00167	5.88e-23	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HHFOALAE_00169	7.5e-36	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HHFOALAE_00171	3.64e-128	-	-	-	L	-	-	-	reverse transcriptase
HHFOALAE_00172	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HHFOALAE_00174	7.39e-124	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HHFOALAE_00175	4.58e-134	-	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HHFOALAE_00176	1.99e-18	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HHFOALAE_00178	2.62e-185	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	Transporter
HHFOALAE_00179	4.82e-194	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HHFOALAE_00180	8.5e-303	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HHFOALAE_00181	1.27e-192	icaB	-	-	G	-	-	-	deacetylase
HHFOALAE_00182	6.94e-262	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
HHFOALAE_00183	9.97e-162	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HHFOALAE_00184	5.48e-281	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HHFOALAE_00185	2.59e-232	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HHFOALAE_00186	6.65e-280	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	mutations do not affect methionine salvage in vivo however
HHFOALAE_00187	3.96e-180	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HHFOALAE_00188	0.0	-	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HHFOALAE_00189	0.0	-	-	-	M	-	-	-	GBS Bsp-like repeat
HHFOALAE_00190	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HHFOALAE_00191	8.95e-110	XK27_03390	-	-	S	-	-	-	LURP-one-related
HHFOALAE_00192	4.58e-237	prsA	3.1.3.16, 5.2.1.8	-	O	ko:K01802,ko:K03769,ko:K07533,ko:K20074	-	ko00000,ko01000,ko01009,ko03110	peptidyl-prolyl cis-trans isomerase activity
HHFOALAE_00193	9.8e-154	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-Methyltransferase
HHFOALAE_00194	3.39e-275	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HHFOALAE_00195	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HHFOALAE_00196	7.45e-210	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HHFOALAE_00197	0.0	-	-	-	S	-	-	-	Glucan-binding protein C
HHFOALAE_00198	2.87e-134	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
HHFOALAE_00199	3.03e-215	-	-	-	K	-	-	-	transcriptional regulator (lysR family)
HHFOALAE_00200	1.35e-202	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HHFOALAE_00201	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HHFOALAE_00205	7.81e-241	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HHFOALAE_00206	1.97e-207	sip	-	-	M	-	-	-	LysM domain protein
HHFOALAE_00207	2.72e-46	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HHFOALAE_00208	2.34e-205	yitL	-	-	S	ko:K00243	-	ko00000	Protein conserved in bacteria
HHFOALAE_00209	7.89e-118	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HHFOALAE_00210	2.78e-168	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HHFOALAE_00211	1.49e-274	sptS	-	-	T	-	-	-	Histidine kinase
HHFOALAE_00212	2.89e-151	dltr	-	-	T	-	-	-	response regulator
HHFOALAE_00213	4.17e-142	-	2.7.6.5	-	S	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
HHFOALAE_00214	4.5e-144	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HHFOALAE_00215	0.0	lmrA2	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
HHFOALAE_00216	0.0	lmrA1	-	-	V	ko:K02021,ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
HHFOALAE_00217	6.75e-96	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HHFOALAE_00218	2.73e-92	def_1	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HHFOALAE_00219	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHFOALAE_00220	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HHFOALAE_00221	7.31e-269	nadR	-	-	H	-	-	-	adenylyltransferase
HHFOALAE_00222	2.09e-167	-	-	-	F	-	-	-	AdP-ribose pyrophosphatase
HHFOALAE_00223	1.56e-30	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HHFOALAE_00224	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	abc transporter atp-binding protein
HHFOALAE_00225	1.23e-274	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HHFOALAE_00226	2.21e-179	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HHFOALAE_00227	3.79e-188	-	-	-	S	-	-	-	EDD domain protein, DegV family
HHFOALAE_00228	2.63e-82	WQ51_03320	-	-	S	-	-	-	cog cog4835
HHFOALAE_00229	2.71e-168	ydaF_2	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HHFOALAE_00230	1.55e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HHFOALAE_00231	1.99e-64	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HHFOALAE_00232	6.12e-123	-	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	acetyltransferase
HHFOALAE_00233	0.0	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HHFOALAE_00234	0.0	gtf1	-	-	M	-	-	-	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HHFOALAE_00235	5.31e-284	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HHFOALAE_00236	1.22e-269	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
HHFOALAE_00237	1.4e-07	-	-	-	-	-	-	-	-
HHFOALAE_00238	1.88e-292	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HHFOALAE_00239	0.0	gor	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HHFOALAE_00240	0.0	fruA	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HHFOALAE_00241	4.55e-212	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HHFOALAE_00242	5.33e-163	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	transcriptional
HHFOALAE_00243	6.36e-290	rny	-	-	D	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HHFOALAE_00244	6.58e-116	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HHFOALAE_00245	4.63e-177	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HHFOALAE_00246	4.89e-204	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HHFOALAE_00247	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HHFOALAE_00248	1.19e-93	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HHFOALAE_00249	1.85e-83	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HHFOALAE_00250	3.69e-297	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HHFOALAE_00251	5.57e-163	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HHFOALAE_00252	2.61e-208	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HHFOALAE_00253	3.77e-220	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	2-Nitropropane dioxygenase
HHFOALAE_00254	2.12e-40	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HHFOALAE_00255	5.78e-219	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HHFOALAE_00256	2.67e-96	XK27_02735	-	-	K	-	-	-	Transcriptional regulator, MarR family
HHFOALAE_00257	2.27e-179	phaB	5.3.3.14, 5.3.3.18	-	I	ko:K15866,ko:K18474	ko00061,ko00360,ko01120,map00061,map00360,map01120	ko00000,ko00001,ko01000,ko01004	Belongs to the enoyl-CoA hydratase isomerase family
HHFOALAE_00258	1.1e-144	yhfA	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
HHFOALAE_00259	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HHFOALAE_00260	1.26e-243	asnA	6.3.1.1	-	E	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HHFOALAE_00261	6.23e-313	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HHFOALAE_00262	1.27e-175	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HHFOALAE_00263	1.99e-132	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HHFOALAE_00264	3.38e-136	-	-	-	S	-	-	-	Domain of unknown function (DUF1803)
HHFOALAE_00265	1.58e-211	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HHFOALAE_00273	6.69e-287	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HHFOALAE_00274	4.62e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L34
HHFOALAE_00275	5.82e-130	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-quinone reductase (modulator of drug activity B)
HHFOALAE_00276	4.26e-132	-	-	-	K	-	-	-	Transcriptional regulator
HHFOALAE_00277	7.06e-229	jag	-	-	S	ko:K06346	-	ko00000	RNA-binding protein
HHFOALAE_00278	4.24e-187	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HHFOALAE_00279	9.69e-72	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HHFOALAE_00280	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Argininosuccinate lyase
HHFOALAE_00281	3.51e-294	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HHFOALAE_00282	9.29e-168	fasA	-	-	KT	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Response regulator of the LytR AlgR family
HHFOALAE_00283	3.07e-285	fasC	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
HHFOALAE_00284	1.65e-260	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
HHFOALAE_00285	2.1e-193	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
HHFOALAE_00286	9.69e-292	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	signal transduction protein with a C-terminal ATPase domain
HHFOALAE_00287	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HHFOALAE_00288	0.0	amiA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HHFOALAE_00289	1.37e-155	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HHFOALAE_00290	1.69e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HHFOALAE_00291	4.66e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
HHFOALAE_00292	1.94e-115	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HHFOALAE_00293	1.02e-163	-	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
HHFOALAE_00294	1.08e-287	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HHFOALAE_00295	4.11e-101	-	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
HHFOALAE_00296	7.02e-103	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HHFOALAE_00297	1.93e-139	XK27_09620	-	-	S	-	-	-	FMN reductase (NADPH) activity
HHFOALAE_00298	3.61e-307	XK27_09615	-	-	C	ko:K19784	-	ko00000	reductase
HHFOALAE_00299	1.49e-181	nirC_1	-	-	P	-	-	-	Formate nitrite transporter
HHFOALAE_00300	1.17e-124	XK27_08585	-	-	S	ko:K16926	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HHFOALAE_00301	2.08e-236	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HHFOALAE_00302	1.31e-216	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HHFOALAE_00303	1.27e-149	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
HHFOALAE_00304	3.43e-123	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HHFOALAE_00305	5.45e-280	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HHFOALAE_00306	2.06e-107	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HHFOALAE_00307	1.29e-180	-	-	-	S	ko:K07025	-	ko00000	HAD hydrolase, family IA, variant
HHFOALAE_00308	1.58e-200	rrmA	2.1.1.187	-	Q	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	methyltransferase
HHFOALAE_00312	2.83e-116	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HHFOALAE_00313	5.2e-85	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HHFOALAE_00314	1.4e-149	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HHFOALAE_00315	1.84e-145	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HHFOALAE_00317	4.94e-73	ytpP	-	-	CO	-	-	-	Thioredoxin
HHFOALAE_00319	2.5e-258	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
HHFOALAE_00320	1.36e-169	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HHFOALAE_00321	7.45e-131	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
HHFOALAE_00323	1.54e-138	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HHFOALAE_00324	1.05e-36	lanR	-	-	K	ko:K07729	-	ko00000,ko03000	sequence-specific DNA binding
HHFOALAE_00325	1.64e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HHFOALAE_00326	3.39e-226	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
HHFOALAE_00327	7.17e-17	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
HHFOALAE_00328	3.23e-93	comGF	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Competence protein ComGF
HHFOALAE_00329	8.23e-20	-	-	-	NU	-	-	-	Type II secretory pathway pseudopilin
HHFOALAE_00330	2.8e-91	cglD	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	Competence protein
HHFOALAE_00331	2.23e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
HHFOALAE_00332	2.05e-178	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HHFOALAE_00333	6.31e-224	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HHFOALAE_00334	1.37e-91	-	-	-	S	-	-	-	cog cog4699
HHFOALAE_00335	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHFOALAE_00336	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHFOALAE_00337	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HHFOALAE_00338	1.65e-304	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HHFOALAE_00339	1.73e-246	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HHFOALAE_00340	8.29e-100	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
HHFOALAE_00341	0.0	ilvB	2.2.1.6	-	EH	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
HHFOALAE_00342	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
HHFOALAE_00343	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
HHFOALAE_00344	1.87e-76	asp	-	-	S	-	-	-	cog cog1302
HHFOALAE_00345	4.04e-285	norN	-	-	V	-	-	-	Mate efflux family protein
HHFOALAE_00346	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HHFOALAE_00347	0.000366	yebC	-	-	M	-	-	-	Membrane
HHFOALAE_00349	0.0	adh	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HHFOALAE_00350	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HHFOALAE_00351	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
HHFOALAE_00352	0.0	treP	2.7.1.201	-	G	ko:K02817,ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
HHFOALAE_00353	4.11e-161	treR	-	-	K	ko:K03486	-	ko00000,ko03000	trehalose operon
HHFOALAE_00354	1.94e-123	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
HHFOALAE_00356	1.65e-209	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	aldolase
HHFOALAE_00358	3.91e-305	-	-	-	H	-	-	-	gamma-glutamylcysteine synthetase
HHFOALAE_00359	3.03e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein l17
HHFOALAE_00360	7.63e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHFOALAE_00361	1.63e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HHFOALAE_00362	4.42e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HHFOALAE_00363	3.26e-22	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HHFOALAE_00364	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HHFOALAE_00365	4.85e-151	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HHFOALAE_00366	8.65e-293	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HHFOALAE_00367	8.47e-85	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HHFOALAE_00368	9.89e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein l30
HHFOALAE_00369	7e-104	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HHFOALAE_00370	7.15e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HHFOALAE_00371	5.88e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HHFOALAE_00372	3.78e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HHFOALAE_00373	2.03e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HHFOALAE_00374	5.86e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HHFOALAE_00375	5.67e-64	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HHFOALAE_00376	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HHFOALAE_00377	3.08e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HHFOALAE_00378	6.2e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HHFOALAE_00379	4.35e-94	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HHFOALAE_00380	9.44e-153	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HHFOALAE_00381	1.21e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HHFOALAE_00382	8.13e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HHFOALAE_00383	1.45e-195	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HHFOALAE_00384	6e-60	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HHFOALAE_00385	2.13e-135	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HHFOALAE_00386	3.17e-142	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HHFOALAE_00387	4.29e-64	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HHFOALAE_00388	7.25e-240	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HHFOALAE_00389	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase
HHFOALAE_00390	1.21e-47	-	-	-	S	-	-	-	MORN repeat protein
HHFOALAE_00391	8.96e-104	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HHFOALAE_00392	1.06e-315	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HHFOALAE_00393	3.89e-119	flaR	-	-	F	-	-	-	topology modulation protein
HHFOALAE_00395	6.76e-251	ltrA	-	-	S	-	-	-	Low temperature requirement protein
HHFOALAE_00396	5.96e-220	-	-	-	S	-	-	-	membrane
HHFOALAE_00397	1.07e-114	-	-	-	K	-	-	-	sequence-specific DNA binding
HHFOALAE_00398	9.71e-209	-	-	-	L	-	-	-	Replication initiation factor
HHFOALAE_00399	1.95e-26	-	-	-	S	-	-	-	Domain of unknown function (DUF3173)
HHFOALAE_00400	1.01e-276	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HHFOALAE_00402	5.94e-300	rarA	-	-	L	ko:K07478	-	ko00000	ATPase related to the helicase subunit of the Holliday junction resolvase
HHFOALAE_00403	1.73e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HHFOALAE_00404	9.75e-59	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HHFOALAE_00405	5.68e-91	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HHFOALAE_00406	1.34e-62	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HHFOALAE_00407	0.0	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
HHFOALAE_00408	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HHFOALAE_00409	4.46e-19	-	-	-	-	-	-	-	-
HHFOALAE_00410	4.23e-115	-	-	-	K	-	-	-	acetyltransferase
HHFOALAE_00411	8.87e-150	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HHFOALAE_00412	2.78e-157	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HHFOALAE_00413	1.46e-213	XK27_01785	-	-	S	-	-	-	cog cog1284
HHFOALAE_00414	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HHFOALAE_00416	2.17e-304	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HHFOALAE_00417	6.32e-224	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
HHFOALAE_00418	2.37e-66	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
HHFOALAE_00419	3.52e-277	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
HHFOALAE_00420	8.74e-36	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HHFOALAE_00421	1.22e-26	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HHFOALAE_00422	3.34e-92	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HHFOALAE_00423	1.1e-155	-	-	-	L	-	-	-	Helix-turn-helix domain
HHFOALAE_00424	9.53e-156	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
HHFOALAE_00425	7.26e-98	-	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
HHFOALAE_00426	9.69e-77	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	transcriptional
HHFOALAE_00427	2.66e-44	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HHFOALAE_00428	1.07e-217	-	-	-	T	-	-	-	Diguanylate cyclase
HHFOALAE_00429	1.15e-05	-	-	-	M	-	-	-	COG0463, glycosyltransferases involved in cell wall biogenesis
HHFOALAE_00430	3.49e-216	-	-	-	M	-	-	-	COG0463, glycosyltransferases involved in cell wall biogenesis
HHFOALAE_00431	0.0	-	2.4.1.12	GT2	M	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
HHFOALAE_00432	0.0	-	-	-	-	-	-	-	-
HHFOALAE_00433	2.23e-33	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HHFOALAE_00437	3.9e-149	XK27_06885	-	-	L	-	-	-	hydrolase
HHFOALAE_00438	1.83e-70	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator, PadR family
HHFOALAE_00439	6.02e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HHFOALAE_00440	3.42e-143	-	-	-	S	-	-	-	Putative adhesin
HHFOALAE_00441	2.66e-262	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
HHFOALAE_00442	1.69e-125	XK27_06935	-	-	K	-	-	-	transcriptional regulator
HHFOALAE_00443	7.66e-71	XK27_04840	-	-	M	ko:K08987	-	ko00000	Membrane
HHFOALAE_00444	5.32e-13	-	-	-	-	-	-	-	-
HHFOALAE_00445	1.25e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HHFOALAE_00446	6.16e-63	WQ51_01655	-	-	S	-	-	-	Biofilm formation stimulator VEG
HHFOALAE_00447	1.35e-314	dnaC	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HHFOALAE_00448	5.07e-98	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HHFOALAE_00449	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HHFOALAE_00450	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HHFOALAE_00451	1.18e-128	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
HHFOALAE_00452	6.6e-279	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HHFOALAE_00453	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HHFOALAE_00454	1.68e-126	isaA	-	-	M	-	-	-	Immunodominant staphylococcal antigen A
HHFOALAE_00455	7.81e-106	lytE	-	-	M	-	-	-	LysM domain protein
HHFOALAE_00456	4.35e-170	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHFOALAE_00457	3.69e-195	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHFOALAE_00458	2.13e-192	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHFOALAE_00459	2.68e-118	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HHFOALAE_00460	7.05e-168	-	-	-	S	ko:K15539	-	ko00000	sequence-specific DNA binding
HHFOALAE_00461	7.84e-302	ymfH	-	-	S	-	-	-	Peptidase M16
HHFOALAE_00462	1.09e-292	albE	-	-	S	-	-	-	Peptidase M16
HHFOALAE_00463	4.18e-75	yaaA	-	-	S	-	-	-	S4 domain protein YaaA
HHFOALAE_00464	4.85e-257	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HHFOALAE_00465	4.53e-107	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HHFOALAE_00466	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HHFOALAE_00467	1.42e-97	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HHFOALAE_00468	0.0	dex	3.2.1.11	GH66	G	ko:K05988	ko00500,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 66
HHFOALAE_00469	3.71e-300	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HHFOALAE_00470	5.97e-145	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HHFOALAE_00471	1.1e-144	-	-	-	K	-	-	-	Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HHFOALAE_00472	5.88e-242	XK27_00055	-	-	P	-	-	-	Major Facilitator
HHFOALAE_00473	3.52e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HHFOALAE_00474	2.61e-126	-	-	-	V	-	-	-	VanZ like family
HHFOALAE_00475	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
HHFOALAE_00476	8.61e-168	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
HHFOALAE_00477	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HHFOALAE_00478	1.75e-195	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HHFOALAE_00480	2.98e-165	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HHFOALAE_00481	3.82e-243	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
HHFOALAE_00482	1.65e-176	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HHFOALAE_00483	3.28e-296	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
HHFOALAE_00484	7.76e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HHFOALAE_00485	4.28e-97	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HHFOALAE_00486	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HHFOALAE_00487	3.52e-34	-	-	-	-	-	-	-	-
HHFOALAE_00488	4.5e-200	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HHFOALAE_00489	2.41e-233	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HHFOALAE_00490	5.86e-91	adcR	-	-	K	-	-	-	transcriptional
HHFOALAE_00491	3.43e-173	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HHFOALAE_00492	7.69e-167	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
HHFOALAE_00493	4.7e-206	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HHFOALAE_00494	0.0	ptsG	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
HHFOALAE_00495	4.99e-203	rgfB	3.1.3.90	-	L	ko:K06896	ko00500,map00500	ko00000,ko00001,ko01000	Endonuclease/Exonuclease/phosphatase family
HHFOALAE_00496	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HHFOALAE_00497	5.63e-195	Z012_04635	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
HHFOALAE_00498	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter
HHFOALAE_00499	2.37e-161	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
HHFOALAE_00500	6.02e-62	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein transport
HHFOALAE_00501	1.45e-181	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HHFOALAE_00502	1.01e-184	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HHFOALAE_00503	7.72e-295	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HHFOALAE_00504	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HHFOALAE_00505	0.0	XK27_00665	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter
HHFOALAE_00506	1.01e-181	cmpC	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
HHFOALAE_00507	7.72e-57	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HHFOALAE_00508	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HHFOALAE_00510	9.89e-59	-	-	-	-	-	-	-	-
HHFOALAE_00511	5.41e-73	WQ51_06355	-	-	S	-	-	-	TM2 domain
HHFOALAE_00512	1.47e-210	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HHFOALAE_00513	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HHFOALAE_00514	2.73e-28	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HHFOALAE_00515	1.05e-33	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Belongs to the SecE SEC61-gamma family
HHFOALAE_00516	2.8e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HHFOALAE_00517	1.3e-89	-	3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27	-	I	ko:K01096,ko:K19302	ko00550,ko00564,ko01100,map00550,map00564,map01100	ko00000,ko00001,ko01000,ko01011	phosphatidate phosphatase activity
HHFOALAE_00518	9e-186	cof	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HHFOALAE_00519	1.37e-173	-	-	-	K	ko:K22103	-	ko00000,ko03000	transcriptional regulator (DeoR family)
HHFOALAE_00520	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HHFOALAE_00521	1.46e-39	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HHFOALAE_00522	1.32e-192	cylA	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
HHFOALAE_00523	2.2e-171	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
HHFOALAE_00524	2.83e-99	-	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
HHFOALAE_00525	7.25e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HHFOALAE_00526	3.24e-158	mta	-	-	K	ko:K21743	-	ko00000,ko03000	Transcriptional
HHFOALAE_00527	2.58e-155	-	-	-	V	-	-	-	abc transporter atp-binding protein
HHFOALAE_00528	1.44e-273	-	-	-	V	-	-	-	FtsX-like permease family
HHFOALAE_00529	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HHFOALAE_00530	4.15e-193	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HHFOALAE_00531	4.57e-94	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
HHFOALAE_00532	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HHFOALAE_00533	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HHFOALAE_00534	4.93e-141	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HHFOALAE_00535	6.21e-124	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HHFOALAE_00536	1.14e-65	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HHFOALAE_00537	1.45e-281	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HHFOALAE_00538	0.0	mapZ	-	-	D	ko:K20073	-	ko00000	Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
HHFOALAE_00544	7.49e-17	-	-	-	UW	-	-	-	domain, Protein
HHFOALAE_00547	3.46e-287	fliF	2.1.1.72	-	N	ko:K02409,ko:K02410,ko:K03427	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko01000,ko02035,ko02044,ko02048	bacterial-type flagellum-dependent cell motility
HHFOALAE_00548	5.95e-239	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HHFOALAE_00549	3.67e-23	-	-	-	S	-	-	-	Accessory secretory protein Sec, Asp5
HHFOALAE_00550	3.27e-24	-	-	-	S	-	-	-	Accessory secretory protein Sec Asp4
HHFOALAE_00551	1.88e-308	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HHFOALAE_00552	0.0	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HHFOALAE_00553	0.0	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HHFOALAE_00554	2.01e-102	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec system protein Asp3
HHFOALAE_00555	0.0	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system protein Asp2
HHFOALAE_00556	0.0	asp1	-	-	S	ko:K12268	-	ko00000,ko02044	Accessory Sec system protein Asp1
HHFOALAE_00557	2.44e-269	secY2	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the accessory SecA2 SecY2 system specifically required for export of
HHFOALAE_00558	0.0	-	-	-	M	-	-	-	family 8
HHFOALAE_00559	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	ATPase involved in DNA repair
HHFOALAE_00560	1.44e-280	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HHFOALAE_00561	0.0	-	-	-	GM	-	-	-	domain, Protein
HHFOALAE_00562	0.0	-	-	-	M	ko:K08643	-	ko00000,ko01000,ko01002	signal peptide protein, YSIRK family
HHFOALAE_00563	8e-148	-	-	-	L	-	-	-	Transposase
HHFOALAE_00564	2e-179	bipA	-	-	Q	ko:K00666,ko:K03561,ko:K14645	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko01004,ko02000,ko03110	Transposase
HHFOALAE_00565	0.0	-	-	-	M	-	-	-	domain protein
HHFOALAE_00566	4.11e-123	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HHFOALAE_00567	1.65e-111	comFC	-	-	K	ko:K02242	-	ko00000,ko00002,ko02044	competence protein
HHFOALAE_00568	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HHFOALAE_00569	4.32e-140	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HHFOALAE_00570	3.47e-214	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HHFOALAE_00571	1.55e-143	XK27_04065	-	-	S	ko:K04767	-	ko00000	CBS domain
HHFOALAE_00572	4.6e-158	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
HHFOALAE_00573	9.34e-176	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
HHFOALAE_00574	1.64e-184	livM	-	-	E	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HHFOALAE_00575	9.55e-189	livH	-	-	E	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HHFOALAE_00576	7.21e-270	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
HHFOALAE_00577	4.33e-62	ylbG	-	-	S	-	-	-	UPF0298 protein
HHFOALAE_00578	2.52e-92	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
HHFOALAE_00579	3.75e-135	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HHFOALAE_00580	1.06e-145	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HHFOALAE_00581	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	G	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Belongs to the glycosyl hydrolase 68 family
HHFOALAE_00582	0.0	-	3.2.1.26, 3.2.1.65	GH32	G	ko:K01193,ko:K01212	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HHFOALAE_00583	1.14e-277	malY	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HHFOALAE_00584	3.65e-251	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HHFOALAE_00585	0.0	pacL	-	-	P	-	-	-	cation transport ATPase
HHFOALAE_00586	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HHFOALAE_00587	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HHFOALAE_00588	1.67e-129	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HHFOALAE_00589	5.68e-76	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HHFOALAE_00590	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HHFOALAE_00591	2.19e-56	ylxQ	-	-	J	-	-	-	ribosomal protein
HHFOALAE_00592	9.2e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Nucleic-acid-binding protein implicated in transcription termination
HHFOALAE_00593	2.96e-253	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HHFOALAE_00594	1.75e-105	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HHFOALAE_00595	5.98e-247	brpA	-	-	K	-	-	-	Transcriptional
HHFOALAE_00596	2.24e-118	XK27_05885	2.3.1.82	-	M	ko:K18816	-	br01600,ko00000,ko01000,ko01504	phosphinothricin N-acetyltransferase activity
HHFOALAE_00597	1.79e-100	ydiB	-	-	M	ko:K06925	-	ko00000,ko03016	ATPase or kinase
HHFOALAE_00598	7.03e-316	XK27_07275	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HHFOALAE_00599	7.22e-197	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HHFOALAE_00600	4.72e-177	XK27_00940	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Metal-dependent hydrolase
HHFOALAE_00601	2.86e-222	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
HHFOALAE_00602	9.8e-168	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	pts system
HHFOALAE_00603	3.97e-202	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose fructose sorbose family IID component
HHFOALAE_00604	1.62e-87	manO	-	-	S	-	-	-	Protein conserved in bacteria
HHFOALAE_00605	1.39e-231	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
HHFOALAE_00606	2.04e-167	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	pts system
HHFOALAE_00607	1.22e-216	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose fructose sorbose family IID component
HHFOALAE_00608	7.55e-82	manO	-	-	S	-	-	-	protein conserved in bacteria
HHFOALAE_00609	2.33e-305	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HHFOALAE_00610	1.02e-143	-	-	-	-	-	-	-	-
HHFOALAE_00611	5.05e-315	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HHFOALAE_00612	4.21e-211	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HHFOALAE_00613	9.67e-272	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
HHFOALAE_00614	5.84e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HHFOALAE_00615	0.0	covS	-	-	T	-	-	-	Histidine kinase
HHFOALAE_00616	1.62e-159	csrR	-	-	T	-	-	-	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHFOALAE_00617	3.14e-116	ylbN	-	-	K	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
HHFOALAE_00618	5.87e-166	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Ribosomal RNA small subunit methyltransferase G
HHFOALAE_00619	1.07e-295	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	COG0168 Trk-type K transport systems, membrane components
HHFOALAE_00620	2.7e-155	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
HHFOALAE_00621	3.54e-191	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HHFOALAE_00622	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
HHFOALAE_00623	6.32e-122	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HHFOALAE_00624	2.83e-200	ilvH	-	-	S	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
HHFOALAE_00625	4.3e-106	hmpT	-	-	S	-	-	-	cog cog4720
HHFOALAE_00626	6.09e-176	thiD	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	phosphomethylpyrimidine kinase
HHFOALAE_00627	5.24e-179	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HHFOALAE_00628	3.4e-257	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HHFOALAE_00629	2.2e-134	thiJ-2	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HHFOALAE_00630	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HHFOALAE_00631	1.28e-103	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HHFOALAE_00632	1.34e-236	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HHFOALAE_00633	4.75e-132	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Muramidase (Flagellum-specific)
HHFOALAE_00634	8.27e-180	yodJ	3.4.16.4, 3.4.17.14	-	M	ko:K01286,ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HHFOALAE_00635	3.28e-166	gpmB	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase
HHFOALAE_00636	1.27e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HHFOALAE_00637	3.56e-52	XK27_08630	-	-	T	ko:K07166	-	ko00000	UPF0237 protein
HHFOALAE_00638	6.05e-295	capA	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein
HHFOALAE_00639	6.12e-193	srtB	-	-	S	-	-	-	Sortase family
HHFOALAE_00641	6.1e-40	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
HHFOALAE_00643	2.12e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HHFOALAE_00644	7.02e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HHFOALAE_00645	1.21e-40	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
HHFOALAE_00647	1.13e-192	yitS	-	-	S	-	-	-	DegV family
HHFOALAE_00648	2e-120	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
HHFOALAE_00649	1.44e-171	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHFOALAE_00651	1.22e-89	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HHFOALAE_00652	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HHFOALAE_00654	6.37e-144	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	serine acetyltransferase
HHFOALAE_00655	1.96e-178	-	-	-	S	-	-	-	SseB protein N-terminal domain
HHFOALAE_00656	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HHFOALAE_00657	1.41e-287	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HHFOALAE_00658	1.2e-289	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HHFOALAE_00659	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
HHFOALAE_00660	9.49e-98	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HHFOALAE_00661	3.41e-107	-	-	-	S	-	-	-	Putative small multi-drug export protein
HHFOALAE_00662	1.23e-233	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HHFOALAE_00663	2.48e-176	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HHFOALAE_00664	3.49e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	alkyl hydroperoxide reductase
HHFOALAE_00665	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	alkyl hydroperoxide reductase
HHFOALAE_00667	1.81e-121	XK27_03570	-	-	S	ko:K19784	-	ko00000	reductase
HHFOALAE_00668	7.7e-95	-	-	-	K	-	-	-	Transcriptional regulator, marr family
HHFOALAE_00669	4.88e-49	XK27_02060	-	-	S	-	-	-	Transglycosylase associated protein
HHFOALAE_00670	7.21e-301	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
HHFOALAE_00671	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HHFOALAE_00698	2.38e-157	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HHFOALAE_00699	2.05e-110	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HHFOALAE_00700	1.61e-143	pcsB	-	-	S	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain
HHFOALAE_00701	1.36e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HHFOALAE_00702	1.76e-114	-	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
HHFOALAE_00703	3.84e-278	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HHFOALAE_00704	1.14e-180	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HHFOALAE_00705	1.45e-235	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HHFOALAE_00706	6.59e-41	acpP_1	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HHFOALAE_00707	5.24e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HHFOALAE_00708	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HHFOALAE_00709	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HHFOALAE_00710	1.85e-241	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HHFOALAE_00711	2.3e-129	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HHFOALAE_00712	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HHFOALAE_00713	4.31e-199	-	-	-	S	-	-	-	CHAP domain
HHFOALAE_00714	3.58e-300	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HHFOALAE_00715	6.76e-106	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HHFOALAE_00716	9.42e-258	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HHFOALAE_00717	6.28e-221	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Ketopantoate reductase
HHFOALAE_00718	8.94e-46	-	-	-	-	-	-	-	-
HHFOALAE_00719	7.54e-38	-	-	-	S	-	-	-	AAA ATPase domain
HHFOALAE_00721	7.13e-313	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HHFOALAE_00722	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HHFOALAE_00723	1.56e-89	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HHFOALAE_00724	1.49e-72	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
HHFOALAE_00725	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HHFOALAE_00726	1.07e-103	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HHFOALAE_00727	5.36e-92	-	-	-	K	-	-	-	LytTr DNA-binding domain
HHFOALAE_00729	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HHFOALAE_00731	5.97e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HHFOALAE_00732	1.5e-135	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	3-methyladenine DNA glycosylase
HHFOALAE_00733	2.47e-292	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HHFOALAE_00734	5.07e-261	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HHFOALAE_00735	8.92e-87	spxA_2	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
HHFOALAE_00739	5.61e-300	-	-	-	T	-	-	-	Nacht domain
HHFOALAE_00740	0.0	XK27_00500	-	-	L	-	-	-	the current gene model (or a revised gene model) may contain a
HHFOALAE_00743	2.28e-67	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
HHFOALAE_00745	1.73e-47	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HHFOALAE_00747	1.1e-18	-	-	-	-	-	-	-	-
HHFOALAE_00749	1.69e-24	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Cellulose biosynthesis protein BcsQ
HHFOALAE_00752	7.63e-22	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HHFOALAE_00753	3.76e-62	spd	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HHFOALAE_00754	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HHFOALAE_00755	3.15e-126	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
HHFOALAE_00756	3.87e-300	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HHFOALAE_00757	2.73e-300	-	3.5.2.6	-	V	ko:K01467	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01000	Beta-lactamase enzyme family
HHFOALAE_00758	1.36e-05	-	-	-	-	-	-	-	-
HHFOALAE_00759	3.9e-79	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HHFOALAE_00760	1.87e-53	yabO	-	-	J	-	-	-	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HHFOALAE_00761	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HHFOALAE_00762	1.8e-134	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HHFOALAE_00763	7.47e-259	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HHFOALAE_00764	1.4e-40	yyzM	-	-	S	-	-	-	Protein conserved in bacteria
HHFOALAE_00765	3.38e-254	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HHFOALAE_00766	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HHFOALAE_00767	3.94e-173	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HHFOALAE_00768	5e-275	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
HHFOALAE_00769	8.15e-109	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HHFOALAE_00770	9.43e-155	yoaK	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HHFOALAE_00774	0.0	XK27_10405	-	-	S	-	-	-	Bacterial membrane protein YfhO
HHFOALAE_00775	0.0	ykpA	-	-	S	-	-	-	abc transporter atp-binding protein
HHFOALAE_00776	3.8e-193	XK27_10395	-	-	S	-	-	-	membrane
HHFOALAE_00777	5.54e-243	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
HHFOALAE_00778	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HHFOALAE_00779	0.0	snf	-	-	L	-	-	-	Superfamily II DNA RNA helicases, SNF2 family'
HHFOALAE_00780	4.8e-28	XK27_11680	-	-	-	-	-	-	-
HHFOALAE_00781	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HHFOALAE_00782	2.46e-113	-	-	-	K	-	-	-	histone acetyltransferase HPA2 and related acetyltransferases
HHFOALAE_00783	0.0	mltG	-	-	ADL	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HHFOALAE_00784	1.17e-100	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HHFOALAE_00785	9.19e-213	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HHFOALAE_00786	1.35e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HHFOALAE_00787	3.63e-164	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHFOALAE_00788	2.55e-121	XK27_09705	-	-	S	ko:K06950	-	ko00000	HD superfamily hydrolase
HHFOALAE_00789	2.33e-143	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HHFOALAE_00791	5.78e-310	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HHFOALAE_00792	8.96e-117	-	-	-	K	-	-	-	transcriptional regulator
HHFOALAE_00793	2.31e-48	-	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
HHFOALAE_00794	2.92e-192	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HHFOALAE_00795	2.23e-234	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HHFOALAE_00796	1.3e-126	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HHFOALAE_00797	1.81e-113	ykuL	-	-	S	-	-	-	CBS domain
HHFOALAE_00798	3.65e-169	xerD	-	-	L	-	-	-	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
HHFOALAE_00799	8.23e-157	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HHFOALAE_00800	1.35e-122	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HHFOALAE_00801	1.23e-169	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HHFOALAE_00802	1.07e-18	yidD	-	-	M	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HHFOALAE_00803	2.96e-267	sstT	-	-	E	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HHFOALAE_00804	1.04e-151	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
HHFOALAE_00805	3.44e-240	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HHFOALAE_00806	0.0	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
HHFOALAE_00807	9.91e-210	metQ	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
HHFOALAE_00808	1.21e-185	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HHFOALAE_00809	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4173)
HHFOALAE_00810	1.05e-70	yhaI	-	-	L	-	-	-	Membrane
HHFOALAE_00811	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HHFOALAE_00812	2.89e-197	-	-	-	K	ko:K20342,ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
HHFOALAE_00813	1.35e-131	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Membrane-associated phospholipid phosphatase
HHFOALAE_00814	5.63e-117	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HHFOALAE_00815	5.98e-121	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HHFOALAE_00816	2.7e-312	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	Potassium transporter peripheral membrane component
HHFOALAE_00817	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
HHFOALAE_00819	1.52e-129	xerS	-	-	D	ko:K04763	-	ko00000,ko03036	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
HHFOALAE_00820	8.81e-114	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHFOALAE_00822	4.84e-19	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHFOALAE_00823	2.04e-28	-	-	-	L	-	-	-	Adenine-specific methyltransferase EcoRI
HHFOALAE_00827	1.83e-46	-	-	-	-	-	-	-	-
HHFOALAE_00829	2.4e-05	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
HHFOALAE_00830	2.05e-24	-	-	-	K	-	-	-	Peptidase S24-like
HHFOALAE_00831	4.86e-120	-	-	-	H	-	-	-	Methyltransferase
HHFOALAE_00832	7.46e-117	-	-	-	M	-	-	-	domain protein
HHFOALAE_00833	1.1e-34	WQ51_00785	-	-	-	-	-	-	-
HHFOALAE_00834	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HHFOALAE_00835	6.89e-279	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
HHFOALAE_00836	3.38e-150	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HHFOALAE_00837	9.52e-205	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HHFOALAE_00838	2.4e-256	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HHFOALAE_00839	5.25e-279	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HHFOALAE_00840	5.29e-262	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HHFOALAE_00841	1.22e-70	XK26_04240	-	-	S	-	-	-	Belongs to the UPF0342 family
HHFOALAE_00842	1.11e-214	hicD2	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HHFOALAE_00843	1.02e-298	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HHFOALAE_00844	5.37e-112	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HHFOALAE_00845	9.85e-197	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
HHFOALAE_00846	0.0	msrR	-	-	K	-	-	-	Transcriptional regulator
HHFOALAE_00847	7.51e-195	ydiA	-	-	P	ko:K11041	ko05150,map05150	ko00000,ko00001,ko02042	C4-dicarboxylate transporter malic acid transport
HHFOALAE_00848	1.28e-255	-	-	-	I	-	-	-	acyl-CoA dehydrogenase
HHFOALAE_00849	1.28e-126	mip	-	-	S	-	-	-	hydroperoxide reductase activity
HHFOALAE_00850	0.0	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HHFOALAE_00851	7.55e-69	-	-	-	K	-	-	-	TfoX N-terminal domain
HHFOALAE_00852	3.82e-91	-	-	-	E	-	-	-	cog cog0346
HHFOALAE_00853	5.24e-195	-	-	-	K	ko:K13653	-	ko00000,ko03000	Integron-associated effector binding protein
HHFOALAE_00854	1.01e-116	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HHFOALAE_00855	5.56e-124	-	-	-	-	-	-	-	-
HHFOALAE_00856	1.13e-59	-	-	-	-	-	-	-	-
HHFOALAE_00857	1.41e-74	-	-	-	S	-	-	-	ParE toxin of type II toxin-antitoxin system, parDE
HHFOALAE_00858	7.04e-173	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HHFOALAE_00859	1.13e-167	-	-	-	S	-	-	-	Domain of unknown function (DUF4336)
HHFOALAE_00860	2.8e-259	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	transporter
HHFOALAE_00861	7.14e-193	ChZ00x2	-	-	S	-	-	-	EDD domain protein, DegV family
HHFOALAE_00862	1.64e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HHFOALAE_00863	1.6e-126	yagB	-	-	F	ko:K06950	-	ko00000	HD superfamily hydrolase
HHFOALAE_00864	5.04e-164	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family
HHFOALAE_00865	2.81e-142	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HHFOALAE_00867	2.39e-18	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HHFOALAE_00868	0.0	-	-	-	P	-	-	-	Major facilitator superfamily
HHFOALAE_00869	1.23e-123	tetR	-	-	K	-	-	-	transcriptional regulator
HHFOALAE_00870	2.81e-194	-	-	-	S	-	-	-	Domain of unknown function (DUF4300)
HHFOALAE_00871	8.83e-163	-	-	-	V	-	-	-	CAAX protease self-immunity
HHFOALAE_00872	1.75e-218	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHFOALAE_00873	2.77e-171	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HHFOALAE_00874	1.01e-228	fatB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HHFOALAE_00875	1.6e-160	-	-	-	S	-	-	-	Putative esterase
HHFOALAE_00876	1.98e-201	yegS	-	-	I	-	-	-	Diacylglycerol kinase
HHFOALAE_00877	6.76e-217	-	-	-	S	-	-	-	Domain of unknown function (DUF389)
HHFOALAE_00878	1.09e-42	ytgB	-	-	S	-	-	-	Membrane
HHFOALAE_00879	1.09e-30	-	-	-	S	-	-	-	CsbD-like
HHFOALAE_00880	2.44e-216	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HHFOALAE_00881	7.15e-211	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	Acetoin dehydrogenase E1 component subunit alpha
HHFOALAE_00882	2.16e-221	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	dehydrogenase E1 component
HHFOALAE_00883	8.05e-182	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HHFOALAE_00884	1.46e-107	-	-	-	Q	-	-	-	Methyltransferase domain
HHFOALAE_00885	1.78e-95	-	-	-	K	-	-	-	TetR family transcriptional regulator
HHFOALAE_00886	3.13e-62	-	-	-	-	-	-	-	-
HHFOALAE_00887	2.92e-156	-	-	-	V	-	-	-	CAAX protease self-immunity
HHFOALAE_00889	2.04e-28	-	-	-	M	-	-	-	Bacterial lipoprotein
HHFOALAE_00890	4.62e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
HHFOALAE_00891	8.28e-84	yqeB	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
HHFOALAE_00893	3.73e-68	-	-	-	-	-	-	-	-
HHFOALAE_00894	2.35e-121	-	-	-	S	-	-	-	CAAX protease self-immunity
HHFOALAE_00895	7.78e-150	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HHFOALAE_00896	9.8e-135	-	-	-	-	-	-	-	-
HHFOALAE_00897	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	Sulfate permease and related transporters (MFS superfamily)
HHFOALAE_00898	2.4e-191	XK27_03010	-	-	S	ko:K08986	-	ko00000	TIGR03943 family
HHFOALAE_00899	2.79e-200	XK27_03015	-	-	S	ko:K07089	-	ko00000	permease
HHFOALAE_00901	0.0	tex	-	-	K	ko:K06959	-	ko00000	Transcriptional accessory protein
HHFOALAE_00902	1.66e-109	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HHFOALAE_00903	1.02e-55	WQ51_05770	-	-	KT	-	-	-	PspC domain
HHFOALAE_00904	1.12e-215	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HHFOALAE_00905	5.05e-189	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HHFOALAE_00906	9.98e-28	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HHFOALAE_00907	2.64e-88	ytxH	-	-	S	-	-	-	General stress protein
HHFOALAE_00909	5.02e-228	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
HHFOALAE_00910	0.0	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
HHFOALAE_00911	1.8e-111	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	biotin synthase
HHFOALAE_00913	2.97e-45	XK27_12190	-	-	S	-	-	-	protein conserved in bacteria
HHFOALAE_00914	2.68e-294	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HHFOALAE_00915	2.93e-18	-	-	-	-	-	-	-	-
HHFOALAE_00916	3.55e-84	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HHFOALAE_00917	0.0	-	-	-	L	-	-	-	helicase
HHFOALAE_00919	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HHFOALAE_00920	8.46e-206	-	-	-	M	-	-	-	LysM domain
HHFOALAE_00921	1.22e-36	-	-	-	-	-	-	-	-
HHFOALAE_00922	3.26e-224	-	-	-	S	ko:K07025	-	ko00000	hydrolase
HHFOALAE_00924	2.41e-148	pgm	-	-	G	-	-	-	Phosphoglycerate mutase
HHFOALAE_00925	8.68e-106	-	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HHFOALAE_00926	9.55e-192	-	3.5.1.28	-	M	ko:K01447,ko:K07273	-	ko00000,ko01000	Glycosyl hydrolase, family 25
HHFOALAE_00927	1.07e-33	-	-	-	P	-	-	-	Hemerythrin HHE cation binding domain protein
HHFOALAE_00928	3.07e-203	hmpP2	-	-	G	-	-	-	hydrolase
HHFOALAE_00929	4.89e-146	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HHFOALAE_00930	1.85e-264	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
HHFOALAE_00931	1.04e-170	sdh	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HHFOALAE_00933	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HHFOALAE_00934	1.6e-170	-	-	-	-	-	-	-	-
HHFOALAE_00935	0.0	-	-	-	L	-	-	-	helicase
HHFOALAE_00936	1e-176	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HHFOALAE_00937	4.38e-163	-	-	-	S	-	-	-	Protein conserved in bacteria
HHFOALAE_00938	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HHFOALAE_00939	9.31e-178	-	-	-	S	-	-	-	double-stranded DNA endodeoxyribonuclease activity
HHFOALAE_00940	0.0	-	-	-	M	-	-	-	Right handed beta helix region
HHFOALAE_00941	5.29e-238	spd	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HHFOALAE_00942	3.61e-119	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HHFOALAE_00943	8.1e-188	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HHFOALAE_00944	2.8e-144	sirR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HHFOALAE_00945	3.77e-218	psaA	-	-	P	ko:K11704,ko:K19971,ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HHFOALAE_00946	2.89e-171	mtsC	-	-	P	ko:K11705,ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type Mn2 Zn2 transport systems, permease components
HHFOALAE_00947	1.6e-161	sitB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K10830,ko:K11706,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HHFOALAE_00948	1.95e-93	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HHFOALAE_00949	6.55e-84	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
HHFOALAE_00950	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HHFOALAE_00951	4.49e-235	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HHFOALAE_00952	1.59e-143	sodA	1.15.1.1	-	C	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
HHFOALAE_00953	3.15e-208	-	-	-	V	-	-	-	D-alanyl-D-alanine carboxypeptidase
HHFOALAE_00954	4.92e-135	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type II secretory pathway prepilin signal peptidase PulO and related peptidases
HHFOALAE_00955	1.06e-116	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HHFOALAE_00956	8.12e-103	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HHFOALAE_00957	2.18e-36	yqgQ	-	-	S	-	-	-	protein conserved in bacteria
HHFOALAE_00958	1.33e-225	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HHFOALAE_00959	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HHFOALAE_00960	5.19e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3165)
HHFOALAE_00961	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HHFOALAE_00962	2.13e-255	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HHFOALAE_00963	1.72e-184	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HHFOALAE_00964	4.95e-292	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HHFOALAE_00965	4.01e-298	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HHFOALAE_00966	1.1e-156	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HHFOALAE_00967	1.1e-117	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	cell septum assembly
HHFOALAE_00968	1.13e-40	yggT	-	-	D	ko:K02221	-	ko00000,ko02044	integral membrane protein
HHFOALAE_00969	1.49e-183	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
HHFOALAE_00970	2.89e-193	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
HHFOALAE_00971	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HHFOALAE_00972	5.27e-235	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHFOALAE_00973	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHFOALAE_00974	3.36e-46	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HHFOALAE_00975	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HHFOALAE_00976	2.02e-269	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HHFOALAE_00977	1.03e-282	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate dehydrogenase
HHFOALAE_00978	2.72e-51	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein Hpr
HHFOALAE_00979	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HHFOALAE_00980	0.0	gapN	1.2.1.9	-	C	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HHFOALAE_00981	6.48e-207	XK27_05670	-	-	S	ko:K07017	-	ko00000	Putative esterase
HHFOALAE_00982	2.16e-195	XK27_05675	-	-	S	-	-	-	Esterase
HHFOALAE_00983	3.32e-286	XK27_05680	-	-	M	-	-	-	carbamoylphosphate synthase large subunit
HHFOALAE_00984	2.06e-239	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HHFOALAE_00985	5.27e-147	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HHFOALAE_00986	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	abc transporter atp-binding protein
HHFOALAE_00987	7.55e-53	-	-	-	S	-	-	-	yiaA/B two helix domain
HHFOALAE_00988	2.22e-171	-	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Alpha beta hydrolase
HHFOALAE_00989	0.0	mprF	2.3.2.3	-	J	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HHFOALAE_00990	8.42e-192	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HHFOALAE_00991	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain protein
HHFOALAE_00992	3.36e-191	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HHFOALAE_00993	7.46e-211	ybbR	-	-	S	-	-	-	Protein conserved in bacteria
HHFOALAE_00994	9.24e-317	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HHFOALAE_00995	7.45e-86	mesH	-	-	S	-	-	-	GtrA-like protein
HHFOALAE_00996	1.88e-153	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HHFOALAE_00997	1.5e-185	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HHFOALAE_00998	2.97e-183	zupT	-	-	P	ko:K07238	-	ko00000,ko02000	Mediates zinc uptake. May also transport other divalent cations
HHFOALAE_00999	6.3e-251	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	oxidoreductase
HHFOALAE_01000	0.0	-	-	-	S	-	-	-	phospholipase Carboxylesterase
HHFOALAE_01001	7.83e-206	rfbA	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HHFOALAE_01002	4.07e-144	rmlC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HHFOALAE_01003	3.86e-263	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HHFOALAE_01006	3.13e-275	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HHFOALAE_01007	8.74e-182	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HHFOALAE_01008	3.01e-178	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HHFOALAE_01009	1.77e-151	-	-	-	S	-	-	-	tigr01906
HHFOALAE_01010	1.06e-177	hisJ	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphatase and related hydrolases of the PHP family
HHFOALAE_01011	7.6e-197	XK27_08080	-	-	G	-	-	-	Exopolysaccharide biosynthesis protein
HHFOALAE_01012	4.46e-81	XK27_08085	-	-	-	-	-	-	-
HHFOALAE_01013	2.65e-246	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HHFOALAE_01014	2.92e-231	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HHFOALAE_01015	2.81e-149	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HHFOALAE_01016	3.57e-299	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HHFOALAE_01017	2.36e-137	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HHFOALAE_01018	8.15e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HHFOALAE_01019	1.96e-165	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HHFOALAE_01020	3.8e-174	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HHFOALAE_01021	6.01e-80	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HHFOALAE_01022	1.8e-66	hisE	3.5.4.19, 3.6.1.31, 5.3.1.16	-	E	ko:K01523,ko:K01814,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
HHFOALAE_01023	4.77e-105	-	-	-	-	-	-	-	-
HHFOALAE_01024	2.55e-139	-	-	-	S	-	-	-	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HHFOALAE_01026	4.02e-130	XK27_05505	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHFOALAE_01027	3.98e-184	-	-	-	P	-	-	-	molecular chaperone
HHFOALAE_01028	2.16e-146	-	-	-	S	-	-	-	Carbohydrate-binding domain-containing protein Cthe_2159
HHFOALAE_01029	8.29e-229	-	-	-	M	-	-	-	glycosyl transferase family 2
HHFOALAE_01030	0.0	-	2.4.1.5	GH13	M	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	KxYKxGKxW signal domain protein
HHFOALAE_01031	0.0	-	2.4.1.5	GH13	M	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	KxYKxGKxW signal domain protein
HHFOALAE_01032	0.0	-	2.4.1.5	GH13	M	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	KxYKxGKxW signal domain protein
HHFOALAE_01033	1.96e-309	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HHFOALAE_01034	1.51e-313	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HHFOALAE_01035	3.41e-144	XK27_05445	-	-	G	-	-	-	UDPglucose--hexose-1-phosphate uridylyltransferase
HHFOALAE_01036	1.81e-221	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HHFOALAE_01037	1.23e-176	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HHFOALAE_01038	7.4e-164	-	-	-	Q	-	-	-	Methyltransferase domain
HHFOALAE_01039	6e-86	GnaT	2.5.1.16	-	K	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferase
HHFOALAE_01040	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease recj
HHFOALAE_01041	5.29e-121	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HHFOALAE_01042	5.67e-232	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HHFOALAE_01043	3.15e-163	dnaD	-	-	-	ko:K02086	-	ko00000	-
HHFOALAE_01044	1.06e-152	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HHFOALAE_01046	1.03e-295	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HHFOALAE_01047	2.44e-40	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HHFOALAE_01048	1.02e-197	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HHFOALAE_01049	1.05e-187	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HHFOALAE_01050	9.93e-94	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HHFOALAE_01051	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HHFOALAE_01052	1.94e-185	WQ51_01275	-	-	S	-	-	-	DegV family
HHFOALAE_01053	4.53e-206	XK27_03630	-	-	E	-	-	-	COG2755 Lysophospholipase L1 and related esterases
HHFOALAE_01054	9.58e-126	ypmS	-	-	S	-	-	-	Protein conserved in bacteria
HHFOALAE_01055	3.1e-52	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HHFOALAE_01057	1.38e-226	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate
HHFOALAE_01058	2.15e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HHFOALAE_01059	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HHFOALAE_01060	1.36e-241	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HHFOALAE_01061	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HHFOALAE_01062	5.58e-146	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HHFOALAE_01063	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HHFOALAE_01064	1.29e-236	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HHFOALAE_01065	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HHFOALAE_01066	2.96e-123	-	-	-	-	-	-	-	-
HHFOALAE_01067	2.24e-71	-	-	-	V	-	-	-	ABC-2 type transporter
HHFOALAE_01068	2.12e-198	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HHFOALAE_01069	5.73e-240	adhP	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HHFOALAE_01070	1.15e-57	-	-	-	-	-	-	-	-
HHFOALAE_01071	3.55e-67	-	-	-	-	-	-	-	-
HHFOALAE_01072	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HHFOALAE_01073	6.16e-200	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HHFOALAE_01074	8.75e-145	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
HHFOALAE_01075	1.67e-135	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter (Permease
HHFOALAE_01076	7.1e-78	phnA	-	-	P	ko:K06193	ko01120,map01120	ko00000	Alkylphosphonate utilization operon protein PhnA
HHFOALAE_01077	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HHFOALAE_01078	5.13e-213	cpsY	-	-	K	-	-	-	Transcriptional regulator
HHFOALAE_01079	9.17e-21	-	-	-	L	ko:K07483	-	ko00000	Transposase
HHFOALAE_01080	0.0	cpdB	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HHFOALAE_01081	6.54e-168	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HHFOALAE_01082	5.2e-225	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HHFOALAE_01083	8.63e-99	-	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HHFOALAE_01084	6.89e-107	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
HHFOALAE_01085	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HHFOALAE_01086	1.24e-101	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HHFOALAE_01087	1.81e-292	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HHFOALAE_01088	1.67e-178	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HHFOALAE_01089	1.53e-112	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	DNA-templated transcription, initiation
HHFOALAE_01090	8.49e-161	-	-	-	S	-	-	-	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
HHFOALAE_01091	0.0	-	3.5.1.28	-	M	ko:K01448,ko:K13733,ko:K20276	ko01503,ko02024,ko05100,map01503,map02024,map05100	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	domain protein
HHFOALAE_01092	0.0	-	2.4.1.5	GH13	M	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	KxYKxGKxW signal domain protein
HHFOALAE_01095	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HHFOALAE_01096	0.0	-	-	-	M	-	-	-	Pilin isopeptide linkage domain protein
HHFOALAE_01097	3.17e-09	-	-	-	-	-	-	-	-
HHFOALAE_01098	1.44e-197	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HHFOALAE_01099	2.2e-129	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HHFOALAE_01100	3.89e-184	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	Hydrolase, tatd
HHFOALAE_01101	2.12e-97	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
HHFOALAE_01102	3.11e-67	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HHFOALAE_01103	3.16e-184	-	-	-	S	-	-	-	Macro domain protein
HHFOALAE_01104	1.05e-51	isplu5A	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
HHFOALAE_01105	1.9e-79	yneP	-	-	L	ko:K07107	-	ko00000,ko01000	thioesterase
HHFOALAE_01106	4.62e-70	bta	1.8.1.8	-	CO	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko03110	cell redox homeostasis
HHFOALAE_01108	1.05e-177	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
HHFOALAE_01109	8.75e-75	-	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HHFOALAE_01110	8.32e-96	-	-	-	L	-	-	-	Transposase
HHFOALAE_01111	6.23e-182	-	-	-	L	ko:K07497	-	ko00000	Transposase and inactivated derivatives
HHFOALAE_01114	6.88e-239	XK27_10075	-	-	S	-	-	-	abc transporter atp-binding protein
HHFOALAE_01115	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
HHFOALAE_01116	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	abc transporter atp-binding protein
HHFOALAE_01117	0.0	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
HHFOALAE_01119	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
HHFOALAE_01120	6.56e-131	-	-	-	K	-	-	-	Acetyltransferase GNAT Family
HHFOALAE_01121	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HHFOALAE_01122	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HHFOALAE_01123	1.25e-233	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	glucose-1-phosphate adenylyltransferase
HHFOALAE_01124	1.08e-251	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HHFOALAE_01125	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HHFOALAE_01126	0.0	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
HHFOALAE_01127	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HHFOALAE_01128	3.19e-238	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HHFOALAE_01129	1.98e-174	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HHFOALAE_01130	1.85e-121	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HHFOALAE_01133	1.9e-146	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HHFOALAE_01134	1.46e-220	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HHFOALAE_01135	9.97e-151	yvqF	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Membrane
HHFOALAE_01136	2.42e-141	-	-	-	P	ko:K10716	-	ko00000,ko02000	Ion transport protein
HHFOALAE_01137	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HHFOALAE_01138	2.57e-173	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HHFOALAE_01139	1.28e-311	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HHFOALAE_01140	2.36e-218	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HHFOALAE_01141	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HHFOALAE_01142	1.37e-61	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-directed 5'-3' RNA polymerase activity
HHFOALAE_01143	4.34e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HHFOALAE_01144	6.43e-271	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HHFOALAE_01145	4.13e-188	XK27_02985	-	-	S	-	-	-	overlaps another CDS with the same product name
HHFOALAE_01146	1.83e-187	-	-	-	S	-	-	-	overlaps another CDS with the same product name
HHFOALAE_01147	8.13e-82	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional
HHFOALAE_01148	2.9e-159	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
HHFOALAE_01149	3.17e-166	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HHFOALAE_01150	3.35e-217	amiF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HHFOALAE_01151	1.98e-258	amiE	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HHFOALAE_01152	4.52e-210	amiD	-	-	P	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
HHFOALAE_01153	0.0	amiC	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
HHFOALAE_01154	0.0	amiA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HHFOALAE_01155	0.0	amiA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HHFOALAE_01156	7.62e-223	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HHFOALAE_01157	1.05e-219	yjbO	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HHFOALAE_01158	5.67e-196	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HHFOALAE_01159	5.79e-154	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Gtp pyrophosphokinase
HHFOALAE_01160	3.35e-131	yjbK	-	-	S	-	-	-	Adenylate cyclase
HHFOALAE_01161	8.28e-225	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HHFOALAE_01162	9.16e-264	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HHFOALAE_01163	1.52e-79	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HHFOALAE_01164	3.84e-153	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HHFOALAE_01165	4.68e-169	-	-	-	T	ko:K07010	-	ko00000,ko01002	peptidase C26
HHFOALAE_01166	2.2e-152	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
HHFOALAE_01167	0.0	rgpF	-	-	M	ko:K07272	-	ko00000,ko01000,ko01003,ko01005	Rhamnan synthesis protein F
HHFOALAE_01168	1.25e-283	rgpD	3.6.3.40	-	P	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HHFOALAE_01169	2.19e-181	-	-	-	GM	ko:K01992,ko:K09690,ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HHFOALAE_01170	1.01e-224	rgpB	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HHFOALAE_01171	1.35e-287	rgpA	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	Domain of unknown function (DUF1972)
HHFOALAE_01172	7.11e-293	-	-	GT4	M	ko:K00754	-	ko00000,ko01000	transferase activity, transferring glycosyl groups
HHFOALAE_01173	2.84e-280	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
HHFOALAE_01174	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HHFOALAE_01175	1e-122	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHFOALAE_01176	3.06e-192	-	-	-	S	-	-	-	Glycosyltransferase group 2 family protein
HHFOALAE_01177	1.68e-58	-	-	-	S	ko:K09153	-	ko00000	Uncharacterized conserved protein (DUF2304)
HHFOALAE_01178	2.1e-163	arnC	-	-	M	ko:K00786	-	ko00000,ko01000	group 2 family protein
HHFOALAE_01179	1.61e-226	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HHFOALAE_01180	2.46e-201	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HHFOALAE_01181	1.71e-284	-	-	-	S	-	-	-	membrane protein involved in the export of O-antigen and teichoic acid
HHFOALAE_01182	5.74e-205	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HHFOALAE_01183	0.0	-	-	-	S	-	-	-	Glucosyl transferase GtrII
HHFOALAE_01184	2.18e-217	yfdH	-	GT2	M	ko:K12999,ko:K20534	-	ko00000,ko01000,ko01003,ko01005,ko02000	COG0463, glycosyltransferases involved in cell wall biogenesis
HHFOALAE_01185	4.86e-74	yitW	-	-	K	-	-	-	metal-sulfur cluster biosynthetic enzyme
HHFOALAE_01186	2.49e-256	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HHFOALAE_01187	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HHFOALAE_01188	1.21e-65	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HHFOALAE_01189	1.9e-27	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HHFOALAE_01190	1.84e-167	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HHFOALAE_01191	1.66e-270	arcT	-	-	E	-	-	-	Aminotransferase
HHFOALAE_01192	6.55e-179	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HHFOALAE_01193	5.16e-181	XK27_04395	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter
HHFOALAE_01194	2.51e-108	XK27_04400	3.6.1.55	-	F	ko:K03574,ko:K12944	-	ko00000,ko01000,ko03400	Nudix family
HHFOALAE_01196	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HHFOALAE_01198	9.45e-209	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
HHFOALAE_01199	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type amino acid transport signal transduction systems periplasmic component domain
HHFOALAE_01200	2.3e-172	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
HHFOALAE_01201	5.23e-25	XK27_00735	-	-	-	-	-	-	-
HHFOALAE_01202	3.8e-315	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HHFOALAE_01203	9.86e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
HHFOALAE_01204	2.38e-168	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HHFOALAE_01205	6.79e-08	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HHFOALAE_01206	7.79e-80	-	-	-	Q	ko:K02614	ko00360,map00360	ko00000,ko00001,ko01000	protein possibly involved in aromatic compounds catabolism
HHFOALAE_01207	3.5e-81	ycaO	-	-	O	ko:K06889,ko:K07397,ko:K09136	-	ko00000,ko03009	OsmC-like protein
HHFOALAE_01209	1.3e-187	-	-	-	EG	-	-	-	Permeases of the drug metabolite transporter (DMT) superfamily
HHFOALAE_01211	6.59e-143	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	phosphoserine phosphatase
HHFOALAE_01212	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HHFOALAE_01213	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HHFOALAE_01214	5.1e-127	-	-	-	S	-	-	-	IA, variant 1
HHFOALAE_01215	6.23e-149	lrgB	-	-	M	-	-	-	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HHFOALAE_01216	5.9e-74	lrgA	-	-	S	ko:K06518	-	ko00000,ko02000	Effector of murein hydrolase LrgA
HHFOALAE_01218	1.6e-86	ogt	2.1.1.63, 3.2.2.20	-	L	ko:K00567,ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	methylated-DNA-[protein]-cysteine S-methyltransferase activity
HHFOALAE_01219	1.06e-278	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHFOALAE_01220	2.79e-136	-	-	-	M	-	-	-	Acetyltransferase (GNAT) domain
HHFOALAE_01221	5.98e-266	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HHFOALAE_01222	2.13e-203	-	-	-	GK	-	-	-	ROK family
HHFOALAE_01223	2.36e-93	gloA	4.4.1.5	-	E	ko:K01759,ko:K15772	ko00620,ko02010,map00620,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Lactoylglutathione lyase
HHFOALAE_01224	4.79e-196	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	HflC and HflK could regulate a protease
HHFOALAE_01225	3.17e-261	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	spermidine putrescine ABC transporter
HHFOALAE_01226	2.52e-166	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type spermidine putrescine transport system, permease component II
HHFOALAE_01227	2.43e-180	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type spermidine putrescine transport system, permease component I
HHFOALAE_01228	9.28e-271	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HHFOALAE_01229	1.54e-213	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
HHFOALAE_01230	4.62e-106	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HHFOALAE_01231	5.86e-79	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HHFOALAE_01232	0.0	amy	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HHFOALAE_01233	1.23e-186	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HHFOALAE_01234	4.02e-129	folE	3.5.4.16	-	F	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	gtp cyclohydrolase
HHFOALAE_01235	0.0	ydaO	-	-	E	-	-	-	amino acid
HHFOALAE_01236	4.87e-298	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HHFOALAE_01237	3.71e-49	ylqC	-	-	L	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HHFOALAE_01238	1.87e-57	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HHFOALAE_01239	0.000134	yebC	-	-	M	-	-	-	Membrane
HHFOALAE_01240	4.23e-258	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
HHFOALAE_01241	1.65e-160	agrA	-	-	KT	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	phosphorelay signal transduction system
HHFOALAE_01242	1.82e-232	-	-	-	O	-	-	-	protein import
HHFOALAE_01243	3.35e-213	tehB	2.1.1.265	-	PQ	ko:K16868	-	ko00000,ko01000	tellurite resistance protein tehb
HHFOALAE_01244	6.9e-15	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HHFOALAE_01245	2.49e-255	XK27_00915	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HHFOALAE_01247	5.11e-204	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HHFOALAE_01248	2.53e-90	-	-	-	S	-	-	-	QueT transporter
HHFOALAE_01250	4.24e-223	yfjR	-	-	K	-	-	-	regulation of single-species biofilm formation
HHFOALAE_01252	2.05e-232	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HHFOALAE_01253	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HHFOALAE_01254	1.71e-111	ccl	-	-	S	-	-	-	cog cog4708
HHFOALAE_01255	1.1e-208	rbn	-	-	E	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HHFOALAE_01256	2.01e-211	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
HHFOALAE_01257	7.45e-296	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
HHFOALAE_01258	1.44e-127	XK27_07830	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase GNAT Family
HHFOALAE_01259	1.49e-292	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HHFOALAE_01260	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HHFOALAE_01261	7.27e-132	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
HHFOALAE_01262	2.5e-183	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HHFOALAE_01263	3.17e-203	nodB3	-	-	G	-	-	-	deacetylase
HHFOALAE_01264	1.75e-180	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase
HHFOALAE_01265	6.85e-55	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
HHFOALAE_01266	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HHFOALAE_01267	1.1e-202	corA	-	-	P	-	-	-	CorA-like protein
HHFOALAE_01268	1.51e-82	yjqA	-	-	S	-	-	-	Bacterial PH domain
HHFOALAE_01269	5.34e-128	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter
HHFOALAE_01270	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HHFOALAE_01271	1.61e-146	ywaF	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
HHFOALAE_01272	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HHFOALAE_01275	1.1e-198	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HHFOALAE_01276	1.81e-172	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
HHFOALAE_01277	1.6e-148	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter (Permease
HHFOALAE_01278	2.02e-147	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter (Permease
HHFOALAE_01279	7.59e-245	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HHFOALAE_01280	2.72e-42	copZ	-	-	P	-	-	-	Heavy metal-associated domain protein
HHFOALAE_01281	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HHFOALAE_01282	3.52e-96	copY	-	-	K	-	-	-	negative regulation of transcription, DNA-templated
HHFOALAE_01283	2.04e-225	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
HHFOALAE_01285	7.14e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HHFOALAE_01286	1e-290	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HHFOALAE_01287	1.71e-125	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the TrpF family
HHFOALAE_01288	3.23e-172	trpC	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HHFOALAE_01289	5.2e-229	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HHFOALAE_01290	7.09e-136	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	anthranilate
HHFOALAE_01291	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HHFOALAE_01292	3.78e-76	-	-	-	-	-	-	-	-
HHFOALAE_01293	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HHFOALAE_01294	7.27e-58	-	-	-	-	-	-	-	-
HHFOALAE_01295	8.92e-68	-	-	-	-	-	-	-	-
HHFOALAE_01296	5.31e-59	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HHFOALAE_01298	1.59e-160	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
HHFOALAE_01299	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (Permease
HHFOALAE_01300	4.78e-163	-	-	-	K	-	-	-	transcriptional regulator, MerR family
HHFOALAE_01301	1.26e-133	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HHFOALAE_01302	5.18e-76	WQ51_02910	-	-	S	-	-	-	Protein of unknown function, DUF536
HHFOALAE_01303	9.99e-86	XK27_02560	-	-	S	-	-	-	cog cog2151
HHFOALAE_01304	0.0	ilvD	4.2.1.9	-	E	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
HHFOALAE_01305	1.25e-284	ytfP	-	-	S	ko:K07007	-	ko00000	Flavoprotein
HHFOALAE_01307	1.25e-155	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HHFOALAE_01308	2.95e-197	ytmP	-	-	M	-	-	-	Phosphotransferase
HHFOALAE_01309	2.24e-218	XK27_05910	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
HHFOALAE_01310	3.39e-168	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
HHFOALAE_01311	1.24e-94	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HHFOALAE_01315	1.98e-133	-	-	-	-	-	-	-	-
HHFOALAE_01317	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	ATP-dependent Clp protease ATP-binding subunit
HHFOALAE_01318	7.3e-59	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	Addiction module toxin, Txe YoeB family
HHFOALAE_01319	6.54e-53	yefM	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HHFOALAE_01320	2.65e-248	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HHFOALAE_01321	6.13e-177	XK27_06665	-	-	Q	-	-	-	Methyltransferase domain protein
HHFOALAE_01322	5.28e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HHFOALAE_01323	2.53e-107	yveA	-	-	Q	-	-	-	Isochorismatase family
HHFOALAE_01324	9.98e-136	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
HHFOALAE_01325	6.44e-152	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HHFOALAE_01326	4.57e-65	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HHFOALAE_01327	9.31e-274	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HHFOALAE_01328	6.17e-126	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
HHFOALAE_01329	1.85e-180	-	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HHFOALAE_01330	1.15e-82	-	-	-	-	-	-	-	-
HHFOALAE_01331	4.98e-280	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHFOALAE_01332	2.78e-73	-	-	-	-	-	-	-	-
HHFOALAE_01333	4.76e-53	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system cellobiose-specific component IIA
HHFOALAE_01334	0.0	celR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HHFOALAE_01335	4.78e-62	celB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HHFOALAE_01336	1.55e-42	-	-	-	S	ko:K15383	-	ko00000,ko02000	PQ loop repeat
HHFOALAE_01337	0.0	celA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HHFOALAE_01339	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HHFOALAE_01340	2.16e-159	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HHFOALAE_01341	3.65e-222	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HHFOALAE_01342	1.44e-254	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HHFOALAE_01343	6.17e-158	-	-	-	L	-	-	-	DNA alkylation repair enzyme
HHFOALAE_01344	0.0	clsA_1	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHFOALAE_01345	8.14e-115	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	acetyltransferase
HHFOALAE_01346	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHFOALAE_01347	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HHFOALAE_01348	1.29e-166	yfnB	3.8.1.2	-	E	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	hydrolase
HHFOALAE_01349	3.15e-154	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HHFOALAE_01350	5.34e-188	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HHFOALAE_01351	0.0	-	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HHFOALAE_01352	4.33e-207	yjlA	-	-	EG	-	-	-	membrane
HHFOALAE_01353	4.66e-103	-	-	-	S	-	-	-	RDD family
HHFOALAE_01354	2e-180	-	-	-	K	ko:K20342,ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
HHFOALAE_01355	2.32e-197	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HHFOALAE_01356	4.12e-144	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HHFOALAE_01357	7.8e-167	-	-	-	K	ko:K20342,ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
HHFOALAE_01358	6.46e-18	-	-	-	-	-	-	-	-
HHFOALAE_01359	4.61e-43	-	-	-	-	-	-	-	-
HHFOALAE_01360	8.42e-102	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HHFOALAE_01361	2.89e-102	-	-	-	-	-	-	-	-
HHFOALAE_01365	1e-36	yfjR	-	-	K	-	-	-	regulation of single-species biofilm formation
HHFOALAE_01366	1.14e-154	-	-	-	S	-	-	-	Protein of unknown function DUF262
HHFOALAE_01367	3.89e-252	-	-	-	S	-	-	-	Protein of unknown function DUF262
HHFOALAE_01368	4.49e-129	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HHFOALAE_01369	2.8e-237	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HHFOALAE_01370	2.04e-170	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HHFOALAE_01371	1.07e-205	XK27_09825	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	'abc transporter, ATP-binding protein
HHFOALAE_01374	3.06e-212	yocS	-	-	S	ko:K03453	-	ko00000	Transporter
HHFOALAE_01375	1.64e-105	-	-	-	F	-	-	-	cytidine deaminase activity
HHFOALAE_01376	5.42e-150	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transporter
HHFOALAE_01377	1.39e-201	XK27_09825	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
HHFOALAE_01380	1.67e-120	XK27_05000	-	-	S	ko:K06940	-	ko00000	metal cluster binding
HHFOALAE_01381	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
HHFOALAE_01382	1.05e-171	yxdL	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HHFOALAE_01383	2.4e-197	-	-	-	T	-	-	-	Histidine kinase
HHFOALAE_01384	3.69e-159	graR	-	-	KT	ko:K19082	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHFOALAE_01385	1.03e-126	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HHFOALAE_01386	5.96e-284	pbuX	-	-	F	ko:K16169	-	ko00000,ko02000	xanthine permease
HHFOALAE_01387	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	(ABC) transporter
HHFOALAE_01388	2.27e-183	-	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
HHFOALAE_01389	8.07e-314	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
HHFOALAE_01391	1.25e-236	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HHFOALAE_01392	3.02e-294	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HHFOALAE_01393	5.88e-229	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HHFOALAE_01394	1.03e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HHFOALAE_01395	1.68e-138	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HHFOALAE_01396	3.6e-30	-	-	-	S	-	-	-	CsbD-like
HHFOALAE_01397	1.05e-256	-	-	-	S	-	-	-	Carbohydrate-binding domain-containing protein Cthe_2159
HHFOALAE_01398	1.7e-66	-	-	-	S	-	-	-	ASCH
HHFOALAE_01399	3.95e-295	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
HHFOALAE_01400	0.0	-	-	-	S	-	-	-	dextransucrase activity
HHFOALAE_01401	1.03e-61	-	-	-	S	-	-	-	dextransucrase activity
HHFOALAE_01403	3.26e-176	tcyC2	-	-	E	ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
HHFOALAE_01404	2.02e-148	-	-	-	P	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
HHFOALAE_01405	2.25e-146	-	-	-	P	ko:K16958	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
HHFOALAE_01406	1.17e-211	-	-	-	ET	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HHFOALAE_01407	3.59e-219	-	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen decarboxylase (URO-D)
HHFOALAE_01408	1.61e-107	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HHFOALAE_01409	1.39e-56	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HHFOALAE_01410	6.33e-256	-	-	-	P	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HHFOALAE_01411	5.24e-159	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
HHFOALAE_01412	3.25e-126	-	-	-	K	-	-	-	WHG domain
HHFOALAE_01413	8.22e-217	ydhF	-	-	S	-	-	-	Aldo keto reductase
HHFOALAE_01415	1.39e-36	XK27_07105	-	-	K	ko:K07729	-	ko00000,ko03000	transcriptional
HHFOALAE_01416	2.24e-46	-	-	-	-	-	-	-	-
HHFOALAE_01417	3.2e-138	XK27_02070	-	-	S	ko:K07078	-	ko00000	nitroreductase
HHFOALAE_01418	1.29e-195	catE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
HHFOALAE_01419	1.72e-99	ywnA_2	-	-	K	-	-	-	Transcriptional regulator
HHFOALAE_01420	2.81e-198	-	-	-	E	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HHFOALAE_01421	6.86e-294	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHFOALAE_01422	8.7e-141	yodC	-	-	C	-	-	-	nitroreductase
HHFOALAE_01423	1.15e-138	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HHFOALAE_01424	4.44e-51	-	-	-	DJ	ko:K06218	-	ko00000,ko02048	nuclease activity
HHFOALAE_01425	4.94e-40	XK27_10490	-	-	-	-	-	-	-
HHFOALAE_01426	3.3e-198	yvgN	-	-	C	-	-	-	reductase
HHFOALAE_01427	7.02e-268	-	-	-	S	-	-	-	Tetratricopeptide repeat
HHFOALAE_01428	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	-beta-galactosidase
HHFOALAE_01429	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	transporter
HHFOALAE_01430	1.09e-253	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HHFOALAE_01431	1.66e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HHFOALAE_01432	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDPglucose--hexose-1-phosphate uridylyltransferase
HHFOALAE_01433	8.11e-283	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HHFOALAE_01434	9.61e-194	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HHFOALAE_01435	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	COG0366 Glycosidases
HHFOALAE_01436	5.53e-286	vncS	2.7.13.3	-	T	ko:K10819	-	ko00000,ko01000	Histidine kinase
HHFOALAE_01437	5.24e-150	vncR	-	-	K	-	-	-	Response regulator receiver domain protein
HHFOALAE_01438	1.59e-304	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HHFOALAE_01439	2.14e-141	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
HHFOALAE_01440	5.57e-260	vex1	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HHFOALAE_01441	0.0	XK27_07020	-	-	S	-	-	-	Belongs to the UPF0371 family
HHFOALAE_01443	7e-250	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	glycerol dehydrogenase
HHFOALAE_01444	6.1e-229	XK27_10475	-	-	S	-	-	-	oxidoreductase
HHFOALAE_01445	1.65e-76	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	dihydroxyacetone kinase, phosphotransfer subunit
HHFOALAE_01446	1.92e-121	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dihydroxyacetone kinase
HHFOALAE_01447	3.95e-226	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dihydroxyacetone kinase
HHFOALAE_01448	4.06e-286	-	-	-	K	-	-	-	Psort location CytoplasmicMembrane, score
HHFOALAE_01449	0.0	tcdB	-	-	M	ko:K11063	ko02024,map02024	ko00000,ko00001,ko02042	Putative cell wall binding repeat
HHFOALAE_01450	1.01e-173	-	-	-	T	-	-	-	Ser Thr phosphatase family protein
HHFOALAE_01451	1.12e-47	-	-	-	S	-	-	-	Immunity protein 41
HHFOALAE_01452	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HHFOALAE_01453	5.61e-09	-	-	-	S	-	-	-	Enterocin A Immunity
HHFOALAE_01454	5.14e-245	mccF	-	-	V	-	-	-	LD-carboxypeptidase
HHFOALAE_01455	2.25e-15	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HHFOALAE_01456	1.21e-58	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HHFOALAE_01457	2.02e-145	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
HHFOALAE_01458	2.43e-10	-	-	-	S	-	-	-	Enterocin A Immunity
HHFOALAE_01459	0.0	-	2.4.1.5	GH13	M	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	KxYKxGKxW signal domain protein
HHFOALAE_01461	0.0	-	-	-	S	-	-	-	dextransucrase activity
HHFOALAE_01462	0.0	-	2.4.1.5	GH13	M	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	KxYKxGKxW signal domain protein
HHFOALAE_01463	1.3e-119	tcdB	-	-	M	ko:K11063	ko02024,map02024	ko00000,ko00001,ko02042	Putative cell wall binding repeat
HHFOALAE_01464	0.0	-	-	-	S	-	-	-	dextransucrase activity
HHFOALAE_01465	1.03e-293	-	-	-	S	-	-	-	dextransucrase activity
HHFOALAE_01466	0.0	-	-	-	S	-	-	-	dextransucrase activity
HHFOALAE_01467	6.92e-104	tcdB	-	-	M	ko:K11063	ko02024,map02024	ko00000,ko00001,ko02042	Putative cell wall binding repeat
HHFOALAE_01468	0.0	tcdB	-	-	S	ko:K11063	ko02024,map02024	ko00000,ko00001,ko02042	dextransucrase activity
HHFOALAE_01469	0.0	-	-	-	S	-	-	-	dextransucrase activity
HHFOALAE_01470	6.44e-132	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HHFOALAE_01471	1.68e-199	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HHFOALAE_01472	0.0	-	-	-	S	-	-	-	dextransucrase activity
HHFOALAE_01473	0.0	-	-	-	S	-	-	-	dextransucrase activity
HHFOALAE_01474	0.0	-	-	-	S	-	-	-	dextransucrase activity
HHFOALAE_01475	0.0	tcdB	-	-	M	ko:K11063	ko02024,map02024	ko00000,ko00001,ko02042	Putative cell wall binding repeat
HHFOALAE_01476	7.15e-283	-	-	-	S	-	-	-	dextransucrase activity
HHFOALAE_01478	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HHFOALAE_01479	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HHFOALAE_01480	7.49e-64	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HHFOALAE_01481	1.44e-291	gtf1	-	-	M	-	-	-	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HHFOALAE_01482	7.37e-235	-	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HHFOALAE_01483	6.91e-202	-	-	-	H	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
HHFOALAE_01484	6.1e-276	-	-	-	M	-	-	-	lipopolysaccharide 3-alpha-galactosyltransferase activity
HHFOALAE_01485	0.0	ascB	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HHFOALAE_01486	1.18e-127	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	isochorismatase
HHFOALAE_01487	2.12e-180	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HHFOALAE_01488	4.15e-300	aspC	2.6.1.2, 2.6.1.66	-	E	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HHFOALAE_01489	1.25e-97	XK27_03180	-	-	T	-	-	-	universal stress protein
HHFOALAE_01491	6.98e-202	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HHFOALAE_01493	1.36e-302	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	COG1253 Hemolysins and related proteins containing CBS domains
HHFOALAE_01494	2.39e-181	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
HHFOALAE_01496	4.93e-35	-	-	-	-	-	-	-	-
HHFOALAE_01497	0.0	nhaP1	-	-	P	ko:K03316	-	ko00000	NhaP-type Na H and K H antiporters
HHFOALAE_01499	1.74e-124	mraW1	-	-	J	-	-	-	(SAM)-dependent
HHFOALAE_01500	3.57e-235	ytqA	-	-	S	ko:K07139	-	ko00000	radical SAM protein
HHFOALAE_01501	8.75e-240	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HHFOALAE_01502	1.87e-113	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HHFOALAE_01503	1.52e-136	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
HHFOALAE_01504	1.13e-218	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HHFOALAE_01505	7.33e-14	-	-	-	S	-	-	-	Protein of unknown function (DUF4059)
HHFOALAE_01506	3.11e-166	tcyN	3.6.3.21	-	E	ko:K02028,ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
HHFOALAE_01507	3.29e-207	yxeN	-	-	P	ko:K02029,ko:K16959,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
HHFOALAE_01508	9.45e-196	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC-type amino acid transport signal transduction systems, periplasmic component domain
HHFOALAE_01510	3.58e-260	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HHFOALAE_01511	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	formate acetyltransferase'
HHFOALAE_01512	4.31e-184	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	carbonic anhydrase
HHFOALAE_01513	8.07e-99	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHFOALAE_01515	6.68e-213	-	-	-	V	-	-	-	COG1680 Beta-lactamase class C and other penicillin binding proteins
HHFOALAE_01516	8.94e-178	cppA	-	-	E	-	-	-	CppA N-terminal
HHFOALAE_01517	3.46e-118	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HHFOALAE_01518	1.24e-201	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HHFOALAE_01519	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HHFOALAE_01520	1.47e-60	spiA	-	-	K	ko:K18831	-	ko00000,ko02048,ko03000	sequence-specific DNA binding
HHFOALAE_01523	5.64e-173	-	-	-	KT	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HHFOALAE_01524	7.25e-287	comD	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	signal transduction protein with a C-terminal ATPase domain
HHFOALAE_01529	4.4e-34	-	-	-	S	-	-	-	Bacteriocin class II with double-glycine leader peptide
HHFOALAE_01530	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
HHFOALAE_01531	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
HHFOALAE_01534	3.55e-116	XK27_09885	-	-	V	-	-	-	Glycopeptide antibiotics resistance protein
HHFOALAE_01535	1.11e-285	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HHFOALAE_01536	2.27e-107	yutD	-	-	J	-	-	-	protein conserved in bacteria
HHFOALAE_01537	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HHFOALAE_01538	4.56e-303	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HHFOALAE_01539	1.99e-236	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HHFOALAE_01540	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein
HHFOALAE_01541	5.32e-60	ftsL	-	-	D	-	-	-	cell division protein FtsL
HHFOALAE_01542	2.67e-222	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HHFOALAE_01543	7.71e-130	-	-	-	-	-	-	-	-
HHFOALAE_01545	2.51e-68	-	-	-	J	-	-	-	Protein of unknown function (DUF805)
HHFOALAE_01546	1.6e-80	-	-	-	J	-	-	-	Protein of unknown function (DUF805)
HHFOALAE_01547	6.77e-72	-	-	-	J	-	-	-	Membrane
HHFOALAE_01548	1.85e-284	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HHFOALAE_01549	8.27e-181	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HHFOALAE_01550	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HHFOALAE_01551	1.23e-170	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
HHFOALAE_01552	1.22e-161	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HHFOALAE_01553	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HHFOALAE_01554	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
HHFOALAE_01555	2.39e-310	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
HHFOALAE_01556	2.69e-294	dcuS	2.7.13.3	-	T	ko:K02476,ko:K07701,ko:K07706,ko:K11614	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
HHFOALAE_01557	1.98e-14	-	-	-	-	-	-	-	-
HHFOALAE_01560	6.89e-186	-	-	-	V	ko:K21397	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
HHFOALAE_01562	0.0	-	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	MreB/Mbl protein
HHFOALAE_01563	1.22e-155	-	-	-	S	-	-	-	membrane
HHFOALAE_01564	3.85e-98	XK27_02470	-	-	K	-	-	-	LytTr DNA-binding domain protein
HHFOALAE_01565	0.0	-	-	-	KT	-	-	-	response to antibiotic
HHFOALAE_01566	2.48e-171	yebC	-	-	M	-	-	-	Membrane
HHFOALAE_01567	0.0	-	-	-	S	-	-	-	hydrolases of the HAD superfamily
HHFOALAE_01568	2.03e-228	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HHFOALAE_01570	4.07e-43	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
HHFOALAE_01574	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HHFOALAE_01575	3.16e-258	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HHFOALAE_01576	4.94e-79	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HHFOALAE_01577	2.59e-249	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HHFOALAE_01578	8.28e-251	aroH	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HHFOALAE_01579	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HHFOALAE_01581	6.66e-236	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HHFOALAE_01582	6.53e-218	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	Fructokinase
HHFOALAE_01583	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
HHFOALAE_01584	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HHFOALAE_01585	1.01e-224	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	Transcriptional regulator
HHFOALAE_01586	1.09e-95	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HHFOALAE_01587	7.41e-80	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	protein conserved in bacteria
HHFOALAE_01588	1.22e-126	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HHFOALAE_01589	3.59e-111	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HHFOALAE_01590	9.75e-255	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Belongs to the peptidase M24B family
HHFOALAE_01591	2.49e-40	blpT	-	-	-	-	-	-	-
HHFOALAE_01595	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HHFOALAE_01596	2.01e-216	corA	-	-	P	ko:K03284	-	ko00000,ko02000	COG0598 Mg2 and Co2 transporters
HHFOALAE_01597	1.39e-157	XK27_01040	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HHFOALAE_01599	4.1e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HHFOALAE_01600	6.66e-115	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HHFOALAE_01601	6.54e-63	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HHFOALAE_01603	5.48e-283	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
HHFOALAE_01605	4.73e-12	-	-	-	-	-	-	-	-
HHFOALAE_01606	4.59e-49	-	-	-	-	-	-	-	-
HHFOALAE_01608	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HHFOALAE_01609	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HHFOALAE_01610	7.99e-120	cvpA	-	-	S	ko:K03558	-	ko00000	toxin biosynthetic process
HHFOALAE_01611	1.18e-20	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HHFOALAE_01612	1.52e-198	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HHFOALAE_01613	5.26e-148	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HHFOALAE_01614	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HHFOALAE_01615	6.6e-62	-	-	-	S	-	-	-	branched-chain amino acid
HHFOALAE_01616	4.01e-145	XK27_12120	-	-	E	-	-	-	AzlC protein
HHFOALAE_01617	2.72e-237	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HHFOALAE_01618	1.73e-93	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HHFOALAE_01619	4.74e-146	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214, inactive homolog of metal-dependent proteases
HHFOALAE_01620	1.3e-44	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HHFOALAE_01621	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HHFOALAE_01622	4.88e-147	sle1	3.5.1.28	CBM50	M	ko:K22409	-	ko00000,ko01000	CHAP domain protein
HHFOALAE_01623	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HHFOALAE_01624	4e-82	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
HHFOALAE_01625	4.38e-113	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
HHFOALAE_01626	3.32e-283	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HHFOALAE_01627	1.43e-160	-	-	-	-	-	-	-	-
HHFOALAE_01628	4.47e-231	gap	1.2.1.12	-	C	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
HHFOALAE_01629	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HHFOALAE_01630	4.66e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HHFOALAE_01631	4.89e-91	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HHFOALAE_01632	7.91e-184	purR	-	-	F	ko:K09685	-	ko00000,ko03000	operon repressor
HHFOALAE_01633	4.14e-229	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	3'-5' exoribonuclease yhaM
HHFOALAE_01634	2.42e-231	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC domain protein
HHFOALAE_01635	4.35e-150	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HHFOALAE_01636	1.15e-154	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HHFOALAE_01637	2.08e-206	rsgA	3.1.3.100	-	G	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HHFOALAE_01639	2.04e-225	dacA1	3.4.16.4	-	M	ko:K01286	-	ko00000,ko01000	Belongs to the peptidase S11 family
HHFOALAE_01640	4.93e-303	dacA1	3.4.16.4	-	M	ko:K01286	-	ko00000,ko01000	Belongs to the peptidase S11 family
HHFOALAE_01641	7.91e-270	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HHFOALAE_01642	3.29e-153	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HHFOALAE_01643	1.15e-297	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HHFOALAE_01644	0.0	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
HHFOALAE_01645	9.21e-287	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
HHFOALAE_01646	4.35e-256	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
HHFOALAE_01647	1.02e-234	acoA	1.2.4.1	-	C	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HHFOALAE_01648	6.61e-231	acoB	1.2.4.1	-	C	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HHFOALAE_01649	7.29e-271	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HHFOALAE_01650	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HHFOALAE_01651	0.0	-	3.5.1.28	-	S	ko:K01448,ko:K02395,ko:K21471	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036	dextransucrase activity
HHFOALAE_01652	0.0	amiA	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-Acetylmuramoyl-L-alanine amidase
HHFOALAE_01653	0.0	pulA2	3.2.1.1, 3.2.1.41	CBM48,GH13	G	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
HHFOALAE_01654	2.29e-194	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
HHFOALAE_01655	3.52e-295	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	peroxidase
HHFOALAE_01656	0.0	ywbL	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
HHFOALAE_01657	1.24e-154	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HHFOALAE_01658	5.62e-33	tatA	-	-	U	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein secretion
HHFOALAE_01659	8.25e-271	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HHFOALAE_01660	2.6e-194	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
HHFOALAE_01661	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
HHFOALAE_01662	5.84e-292	malX	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HHFOALAE_01663	1.33e-199	malR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HHFOALAE_01664	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
HHFOALAE_01665	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HHFOALAE_01667	9.84e-236	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HHFOALAE_01668	8.82e-247	xerS	-	-	D	ko:K04763	-	ko00000,ko03036	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
HHFOALAE_01669	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HHFOALAE_01670	3.82e-148	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HHFOALAE_01671	1.5e-180	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HHFOALAE_01672	7.48e-193	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HHFOALAE_01673	5.16e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	phosphate transport system permease
HHFOALAE_01674	1.33e-200	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HHFOALAE_01675	9.81e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	phosphate
HHFOALAE_01676	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HHFOALAE_01677	2.21e-182	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HHFOALAE_01678	4.17e-60	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HHFOALAE_01679	3.58e-93	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HHFOALAE_01680	1.73e-216	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HHFOALAE_01681	2.4e-193	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HHFOALAE_01682	3.71e-316	XK27_04775	-	-	S	ko:K09155	-	ko00000	hemerythrin HHE cation binding domain
HHFOALAE_01683	7.18e-47	M1-755	-	-	P	ko:K09155	-	ko00000	Hemerythrin HHE cation binding domain protein
HHFOALAE_01684	5.72e-144	hsdS2	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
HHFOALAE_01685	2.02e-112	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HHFOALAE_01686	2.21e-177	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HHFOALAE_01687	5.71e-305	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	o-acetylhomoserine
HHFOALAE_01688	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HHFOALAE_01689	1e-306	agcS	-	-	E	ko:K03310	-	ko00000	(Alanine) symporter
HHFOALAE_01690	4.66e-312	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HHFOALAE_01691	7.78e-225	bglC	-	-	K	-	-	-	Transcriptional regulator
HHFOALAE_01692	0.0	sasH	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HHFOALAE_01693	6.58e-105	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
HHFOALAE_01694	2.29e-190	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HHFOALAE_01695	1.72e-307	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
HHFOALAE_01696	1.02e-143	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HHFOALAE_01697	8.02e-161	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HHFOALAE_01698	6.56e-146	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHFOALAE_01699	1.6e-158	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHFOALAE_01700	9.11e-262	csm5	-	-	L	ko:K19140	-	ko00000,ko02048	CRISPR-associated RAMP protein, Csm5 family
HHFOALAE_01701	5.53e-211	csm4	-	-	L	ko:K19139	-	ko00000,ko02048	CRISPR-associated RAMP protein, Csm4 family
HHFOALAE_01702	3.14e-148	csm3	-	-	L	ko:K09002	-	ko00000,ko02048	RAMP superfamily
HHFOALAE_01703	2.15e-82	-	-	-	L	ko:K19138	-	ko00000,ko02048	Pfam:DUF310
HHFOALAE_01704	0.0	csm1	-	-	S	ko:K07016	-	ko00000,ko02048	CRISPR-associated protein Csm1 family
HHFOALAE_01705	2.13e-171	-	-	-	S	-	-	-	Pfam:DUF2276
HHFOALAE_01706	8.04e-70	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HHFOALAE_01707	3.14e-230	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HHFOALAE_01708	1.38e-225	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HHFOALAE_01709	1.05e-183	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HHFOALAE_01710	3.95e-121	thiJ	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1 family
HHFOALAE_01711	5.08e-170	-	-	-	S	-	-	-	TraX protein
HHFOALAE_01712	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
HHFOALAE_01713	0.0	-	-	-	S	-	-	-	secreted protein
HHFOALAE_01714	0.0	yhaI	-	-	L	-	-	-	Membrane
HHFOALAE_01718	7.37e-201	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HHFOALAE_01719	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHFOALAE_01720	3.94e-292	dinF	-	-	V	-	-	-	Mate efflux family protein
HHFOALAE_01721	1.55e-224	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type enterochelin transport system, periplasmic component
HHFOALAE_01722	0.0	-	-	-	V	-	-	-	Type III restriction enzyme, res subunit
HHFOALAE_01723	6.61e-141	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant 1
HHFOALAE_01724	2.87e-170	-	-	-	F	-	-	-	Phosphorylase superfamily
HHFOALAE_01726	1.07e-238	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
HHFOALAE_01727	5.41e-253	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HHFOALAE_01728	7.76e-205	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HHFOALAE_01729	4.65e-123	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
HHFOALAE_01730	4.08e-90	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
HHFOALAE_01732	1.19e-95	qor	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
HHFOALAE_01733	1.67e-178	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HHFOALAE_01734	8.56e-178	-	-	-	S	-	-	-	Phenazine biosynthesis protein
HHFOALAE_01735	2.07e-142	-	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
HHFOALAE_01736	0.0	proWX	-	-	P	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HHFOALAE_01737	2.58e-167	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
HHFOALAE_01738	6.6e-177	-	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	epimerase
HHFOALAE_01739	1.4e-89	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HHFOALAE_01740	1.9e-172	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
HHFOALAE_01741	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HHFOALAE_01744	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HHFOALAE_01746	2.2e-174	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	Acetoin reductase
HHFOALAE_01747	2.66e-58	-	-	-	P	-	-	-	Rhodanese-like protein
HHFOALAE_01748	3.27e-96	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HHFOALAE_01749	1.51e-282	XK27_05470	-	-	E	-	-	-	Methionine synthase
HHFOALAE_01750	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HHFOALAE_01751	4.29e-289	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HHFOALAE_01752	3.43e-156	yycF1	-	-	T	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHFOALAE_01753	4.82e-188	-	-	-	S	-	-	-	TraX protein
HHFOALAE_01755	2.32e-69	-	-	-	V	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HHFOALAE_01756	1.04e-106	-	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HHFOALAE_01757	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HHFOALAE_01758	5.06e-197	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HHFOALAE_01759	5.5e-210	-	-	-	GK	-	-	-	ROK family
HHFOALAE_01760	4.96e-172	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HHFOALAE_01761	1.4e-201	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HHFOALAE_01762	2.14e-164	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HHFOALAE_01763	9.14e-117	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
HHFOALAE_01764	1.33e-111	-	-	-	-	ko:K16788	-	ko00000,ko02000	-
HHFOALAE_01765	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HHFOALAE_01766	3.35e-73	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HHFOALAE_01767	5.22e-162	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
HHFOALAE_01768	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HHFOALAE_01769	2e-131	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HHFOALAE_01770	8.05e-196	-	-	-	S	-	-	-	Phospholipase, patatin family
HHFOALAE_01771	2.77e-133	-	-	-	E	-	-	-	Lysophospholipase L1 and related esterases
HHFOALAE_01772	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	unusual protein kinase
HHFOALAE_01773	2.35e-52	-	-	-	S	-	-	-	granule-associated protein
HHFOALAE_01774	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HHFOALAE_01775	1.87e-251	XK27_12525	-	-	S	-	-	-	hmm pf01594
HHFOALAE_01776	8.03e-141	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
HHFOALAE_01777	1.07e-137	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
HHFOALAE_01778	4.62e-139	XK27_06100	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
HHFOALAE_01779	2.49e-189	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HHFOALAE_01780	3.88e-264	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HHFOALAE_01781	4.87e-303	-	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HHFOALAE_01782	3.94e-273	-	-	-	-	-	-	-	-
HHFOALAE_01783	8.95e-222	galnac-T15	-	-	S	ko:K07011	-	ko00000	glycosyl transferase family 2
HHFOALAE_01784	1.1e-216	-	-	-	M	-	-	-	Glycosyltransferase
HHFOALAE_01785	1.46e-166	wefC	-	-	M	-	-	-	Stealth protein CR2, conserved region 2
HHFOALAE_01786	8.99e-209	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HHFOALAE_01787	2.71e-152	-	-	-	M	-	-	-	Domain of unknown function (DUF1919)
HHFOALAE_01788	3.2e-265	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
HHFOALAE_01789	2.84e-284	rgpAc	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	group 1 family protein
HHFOALAE_01790	0.0	cpsE	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HHFOALAE_01791	3.77e-146	cpsD	-	-	D	-	-	-	COG0489 ATPases involved in chromosome partitioning
HHFOALAE_01792	2.52e-143	capA	-	-	M	-	-	-	biosynthesis protein
HHFOALAE_01793	2.04e-169	cpsB	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	Capsular polysaccharide biosynthesis protein
HHFOALAE_01794	3.04e-314	cps4A	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HHFOALAE_01795	1.97e-168	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	purine nucleoside phosphorylase
HHFOALAE_01796	6.11e-168	gat	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	glutamine amidotransferase
HHFOALAE_01797	4.38e-224	-	-	-	P	-	-	-	Chloride transporter, ClC family
HHFOALAE_01798	8.49e-67	-	-	-	S	ko:K03744	-	ko00000	LemA family
HHFOALAE_01799	3.01e-184	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HHFOALAE_01800	4.46e-122	-	-	-	S	-	-	-	Protein of unknown function (DUF1697)
HHFOALAE_01801	7.12e-296	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HHFOALAE_01802	5.87e-156	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HHFOALAE_01803	0.0	-	-	-	V	ko:K13732	ko05100,map05100	ko00000,ko00001	Glucan-binding protein C
HHFOALAE_01804	0.0	-	-	-	V	-	-	-	Glucan-binding protein C
HHFOALAE_01805	7.33e-141	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HHFOALAE_01806	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Dipeptidase
HHFOALAE_01807	1.38e-37	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HHFOALAE_01808	2.24e-118	yybC	-	-	-	-	-	-	-
HHFOALAE_01809	2.18e-109	XK27_03610	-	-	K	-	-	-	Gnat family
HHFOALAE_01810	1.82e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HHFOALAE_01811	2.36e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HHFOALAE_01812	1.1e-115	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HHFOALAE_01813	3.39e-155	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HHFOALAE_01814	4.19e-39	XK27_09115	-	-	M	-	-	-	LysM domain
HHFOALAE_01815	4.23e-115	ebsA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HHFOALAE_01816	1.59e-285	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HHFOALAE_01817	0.0	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
HHFOALAE_01818	2.56e-123	sipC	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HHFOALAE_01819	1.25e-283	XK27_05225	-	-	G	-	-	-	COG0457 FOG TPR repeat
HHFOALAE_01820	1.28e-233	XK27_05220	-	-	S	-	-	-	permease
HHFOALAE_01821	5.85e-119	mutX	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NTP pyrophosphohydrolases including oxidative damage repair enzymes
HHFOALAE_01822	1.4e-209	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HHFOALAE_01823	8.67e-160	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
HHFOALAE_01824	1.08e-231	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HHFOALAE_01825	5.54e-266	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HHFOALAE_01826	6.87e-201	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HHFOALAE_01827	2.03e-167	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HHFOALAE_01828	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	cation transport ATPase
HHFOALAE_01829	3.41e-89	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HHFOALAE_01830	2.71e-182	XK27_00115	-	-	K	-	-	-	Acetyltransferase GNAT family
HHFOALAE_01831	7.71e-187	XK27_00835	-	-	S	-	-	-	hydrolases of the HAD superfamily
HHFOALAE_01832	1.37e-289	femX	2.3.2.10, 2.3.2.16	-	V	ko:K05363,ko:K11693	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	protein involved in methicillin resistance
HHFOALAE_01833	4.46e-74	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
HHFOALAE_01834	4.18e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Metal-dependent hydrolases of the beta-lactamase superfamily I
HHFOALAE_01835	8.53e-281	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HHFOALAE_01836	1.44e-165	yycF	-	-	KT	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHFOALAE_01837	3.14e-179	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
HHFOALAE_01838	1.56e-190	peb1A	-	-	ET	ko:K02030,ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type amino acid transport signal transduction systems, periplasmic component domain
HHFOALAE_01839	8.31e-159	XK27_07620	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
HHFOALAE_01840	1.43e-142	-	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HHFOALAE_01841	4.99e-195	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HHFOALAE_01842	2.03e-35	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
HHFOALAE_01843	1.45e-296	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HHFOALAE_01844	1.56e-13	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
HHFOALAE_01845	7.06e-249	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HHFOALAE_01846	3.1e-167	-	-	-	G	-	-	-	Domain of unknown function (DUF4832)
HHFOALAE_01847	6.52e-108	-	-	-	S	-	-	-	membrane
HHFOALAE_01848	9.2e-123	-	-	-	P	-	-	-	VTC domain
HHFOALAE_01849	1.47e-280	-	-	-	M	ko:K06330	-	ko00000	CotH kinase protein
HHFOALAE_01850	6.01e-240	-	-	-	M	ko:K21012	ko02025,map02025	ko00000,ko00001	Putative exopolysaccharide Exporter (EPS-E)
HHFOALAE_01851	0.0	-	2.4.1.52	GT4	M	ko:K00712,ko:K21011	ko02025,map02025	ko00000,ko00001,ko01000,ko01003	Domain of unknown function (DUF3492)
HHFOALAE_01852	0.0	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2194)
HHFOALAE_01853	1.18e-185	-	-	-	-	-	-	-	-
HHFOALAE_01854	0.0	-	5.1.3.2	-	GM	ko:K01784,ko:K21009	ko00052,ko00520,ko01100,ko02025,map00052,map00520,map01100,map02025	ko00000,ko00001,ko00002,ko01000	Psort location CytoplasmicMembrane, score
HHFOALAE_01855	2.1e-269	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HHFOALAE_01856	6.82e-223	birA	6.3.4.15	-	HK	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HHFOALAE_01857	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HHFOALAE_01858	2.16e-114	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HHFOALAE_01859	2.32e-205	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HHFOALAE_01860	9.42e-28	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HHFOALAE_01863	2.33e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HHFOALAE_01864	2.35e-269	eriC	-	-	P	ko:K03281	-	ko00000	Chloride transporter ClC family
HHFOALAE_01865	1.74e-53	pheA	1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5	-	E	ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K14170,ko:K14187	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase
HHFOALAE_01866	0.0	eriC	-	-	P	ko:K03281	-	ko00000	Chloride transporter, ClC family
HHFOALAE_01867	3.48e-98	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HHFOALAE_01868	8.23e-25	XK27_08880	-	-	-	-	-	-	-
HHFOALAE_01869	3.8e-163	XK27_08875	-	-	O	-	-	-	Zinc-dependent metalloprotease
HHFOALAE_01870	7.21e-192	estA	-	CE1	S	ko:K03930	-	ko00000,ko01000	Esterase
HHFOALAE_01871	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HHFOALAE_01872	3.13e-173	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
HHFOALAE_01873	1.37e-190	XK27_08840	-	-	S	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HHFOALAE_01874	6.84e-229	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
HHFOALAE_01876	0.0	crpB	-	-	Q	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
HHFOALAE_01877	8.95e-69	-	-	-	-	-	-	-	-
HHFOALAE_01878	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HHFOALAE_01879	9.23e-169	-	-	-	-	-	-	-	-
HHFOALAE_01883	2.22e-155	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HHFOALAE_01884	8.85e-18	dnaX	2.4.99.16, 2.7.7.7	GH13	D	ko:K02343,ko:K02519,ko:K07114,ko:K16147	ko00230,ko00240,ko00500,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map00500,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko02000,ko03012,ko03029,ko03032,ko03400	cell septum assembly
HHFOALAE_01887	3.39e-105	-	-	-	S	-	-	-	Protein conserved in bacteria
HHFOALAE_01891	1.89e-37	-	-	-	-	-	-	-	-
HHFOALAE_01892	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HHFOALAE_01893	2.26e-112	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HHFOALAE_01894	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system
HHFOALAE_01896	0.0	vpr	3.4.21.96	-	O	ko:K01361,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HHFOALAE_01897	3.19e-41	-	-	-	C	-	-	-	coenzyme F420-1:gamma-L-glutamate ligase activity
HHFOALAE_01900	4.93e-25	-	-	-	S	-	-	-	YcaO cyclodehydratase, ATP-ad Mg2+-binding
HHFOALAE_01902	4.68e-47	-	-	-	-	-	-	-	-
HHFOALAE_01903	1.3e-58	-	-	-	V	-	-	-	ABC transporter transmembrane region
HHFOALAE_01906	1.59e-152	-	-	-	K	-	-	-	transcriptional regulator PlcR
HHFOALAE_01907	7.56e-30	-	-	-	S	-	-	-	Bacteriophage peptidoglycan hydrolase
HHFOALAE_01911	6.8e-135	-	-	-	U	-	-	-	AAA-like domain
HHFOALAE_01914	1e-35	-	-	-	-	-	-	-	-
HHFOALAE_01915	8.96e-126	fic	-	-	D	ko:K04095	-	ko00000,ko03036	nucleotidyltransferase activity
HHFOALAE_01917	3.14e-55	-	-	-	-	-	-	-	-
HHFOALAE_01919	6.82e-156	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
HHFOALAE_01924	4.8e-36	-	-	-	-	-	-	-	-
HHFOALAE_01926	1.06e-07	-	-	-	V	-	-	-	Psort location Cytoplasmic, score
HHFOALAE_01927	2.87e-101	-	-	-	P	-	-	-	Protein conserved in bacteria
HHFOALAE_01928	2.07e-101	-	-	-	F	-	-	-	Belongs to the Nudix hydrolase family
HHFOALAE_01929	1.78e-153	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
HHFOALAE_01930	1.66e-138	-	-	-	K	-	-	-	Transcriptional regulator, AbiEi antitoxin
HHFOALAE_01938	5.22e-39	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
HHFOALAE_01944	1.71e-82	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
HHFOALAE_01945	1.02e-43	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HHFOALAE_01949	1.76e-150	-	-	-	-	-	-	-	-
HHFOALAE_01950	1.35e-108	-	-	-	S	-	-	-	Protein of unknown function (DUF1643)
HHFOALAE_01951	1.24e-50	-	-	-	-	-	-	-	-
HHFOALAE_01958	5.54e-148	-	-	-	U	-	-	-	TraM recognition site of TraD and TraG
HHFOALAE_01960	8.11e-21	-	-	-	S	-	-	-	Ribosomal protein S1-like RNA-binding domain
HHFOALAE_01962	1.43e-62	-	-	-	N	-	-	-	Leucine rich repeats (6 copies)
HHFOALAE_01963	5.63e-164	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	muramidase
HHFOALAE_01964	3.97e-213	yeiH	-	-	S	-	-	-	Membrane
HHFOALAE_01967	0.0	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HHFOALAE_01968	3.66e-187	XK27_10720	-	-	D	-	-	-	peptidase activity
HHFOALAE_01969	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HHFOALAE_01970	4.01e-206	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HHFOALAE_01971	5.25e-233	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HHFOALAE_01972	1.03e-209	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HHFOALAE_01973	1.48e-173	yejC	-	-	S	-	-	-	cyclic nucleotide-binding protein
HHFOALAE_01974	2.7e-307	-	-	-	D	-	-	-	nuclear chromosome segregation
HHFOALAE_01975	5.6e-123	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
HHFOALAE_01976	8.72e-173	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HHFOALAE_01977	2.02e-106	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
HHFOALAE_01978	2.62e-159	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HHFOALAE_01979	3.71e-83	aldR	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	endoribonuclease L-PSP
HHFOALAE_01981	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HHFOALAE_01982	6.82e-273	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HHFOALAE_01983	1.32e-106	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
HHFOALAE_01984	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HHFOALAE_01985	5.3e-156	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
HHFOALAE_01986	4.06e-218	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HHFOALAE_01987	1.53e-243	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HHFOALAE_01988	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HHFOALAE_01989	9.13e-241	-	-	-	S	ko:K07335	-	ko00000	membrane
HHFOALAE_01990	2.46e-84	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HHFOALAE_01991	4.1e-144	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HHFOALAE_01992	4.63e-295	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
HHFOALAE_01993	3.21e-136	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase small domain protein
HHFOALAE_01994	1.55e-219	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HHFOALAE_01995	4.36e-40	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HHFOALAE_01996	5.01e-310	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HHFOALAE_01997	2.39e-154	ciaR	-	-	T	ko:K14983	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHFOALAE_01998	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HHFOALAE_01999	2.97e-145	coaB	6.3.2.5	-	H	ko:K21977	ko00770,map00770	ko00000,ko00001,ko00002,ko01000	Phosphopantothenate-cysteine ligase
HHFOALAE_02000	4.1e-118	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HHFOALAE_02001	4.16e-118	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HHFOALAE_02002	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
HHFOALAE_02003	4.22e-211	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	reductase
HHFOALAE_02004	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HHFOALAE_02006	0.0	pabB	2.6.1.85, 4.1.3.38	-	EH	ko:K01665,ko:K03342,ko:K13950	ko00790,map00790	ko00000,ko00001,ko01000,ko01007	component I
HHFOALAE_02007	0.0	-	3.6.3.2, 3.6.3.6, 3.6.3.8	-	P	ko:K01531,ko:K01535,ko:K01537	ko00190,map00190	ko00000,ko00001,ko01000	cation transport ATPase
HHFOALAE_02008	3.35e-306	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HHFOALAE_02009	7.07e-48	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHFOALAE_02010	8.43e-301	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Membrane protein involved in D-alanine export
HHFOALAE_02011	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHFOALAE_02012	0.0	XK27_10035	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
HHFOALAE_02013	0.0	yfiB1	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	abc transporter atp-binding protein
HHFOALAE_02014	1.25e-127	pvaA	-	-	M	ko:K02395	-	ko00000,ko02035	lytic transglycosylase activity
HHFOALAE_02015	8.65e-228	-	-	-	S	-	-	-	37-kD nucleoid-associated bacterial protein
HHFOALAE_02016	7.69e-293	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HHFOALAE_02017	1.24e-133	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HHFOALAE_02018	2.03e-186	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HHFOALAE_02019	4.58e-247	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HHFOALAE_02020	5.76e-140	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HHFOALAE_02021	1.98e-234	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HHFOALAE_02022	3.06e-194	gst	-	-	O	ko:K11209	-	ko00000,ko01000	Glutathione S-transferase
HHFOALAE_02023	5.01e-226	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	domain protein
HHFOALAE_02024	1.67e-222	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HHFOALAE_02025	3.52e-61	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	50S ribosomal protein L31
HHFOALAE_02026	7.08e-291	mntH_2	-	-	P	-	-	-	Mn2 and Fe2 transporters of the NRAMP family
HHFOALAE_02027	2.21e-208	ypuA	-	-	S	-	-	-	secreted protein
HHFOALAE_02028	3.16e-95	ywkD	-	-	E	ko:K08234	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HHFOALAE_02029	3.1e-169	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase (surface protein transpeptidase)
HHFOALAE_02030	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HHFOALAE_02031	2.92e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HHFOALAE_02032	0.0	noxE	-	-	P	-	-	-	NADH oxidase
HHFOALAE_02033	0.0	yheS_1	-	-	S	-	-	-	abc transporter atp-binding protein
HHFOALAE_02034	1.61e-108	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HHFOALAE_02035	1.62e-196	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Belongs to the pyridoxine kinase family
HHFOALAE_02036	4.9e-111	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HHFOALAE_02038	4.39e-306	ycxD	-	-	K	-	-	-	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HHFOALAE_02039	6.52e-75	nrdD_1	1.1.98.6, 1.17.4.1	-	F	ko:K00525,ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleoside-triphosphate reductase
HHFOALAE_02041	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HHFOALAE_02042	3.58e-119	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHFOALAE_02043	1.13e-250	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HHFOALAE_02044	7.46e-32	WQ51_00220	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
HHFOALAE_02045	5.83e-118	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)