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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HLNKLFDN_00001	1.41e-213	-	-	-	K	-	-	-	Periplasmic binding protein domain
HLNKLFDN_00002	7.33e-289	sstT	-	-	E	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HLNKLFDN_00003	1.98e-184	-	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	RNA pseudouridylate synthase
HLNKLFDN_00004	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HLNKLFDN_00005	1.06e-186	tcyC	3.6.3.21	-	E	ko:K02028,ko:K02029	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HLNKLFDN_00006	2.44e-219	yecS	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_00007	5.01e-206	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
HLNKLFDN_00008	1.44e-51	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
HLNKLFDN_00009	1.01e-205	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
HLNKLFDN_00010	5e-106	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HLNKLFDN_00011	1.68e-225	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain protein
HLNKLFDN_00012	7.75e-206	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in cellular division
HLNKLFDN_00013	8.3e-239	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Cell division ATP-binding protein FtsE
HLNKLFDN_00014	2.95e-263	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HLNKLFDN_00015	5e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HLNKLFDN_00016	9.11e-216	dapD	2.3.1.117	-	E	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
HLNKLFDN_00017	0.0	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
HLNKLFDN_00018	5.71e-193	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HLNKLFDN_00019	0.0	pepO	3.4.24.11, 3.4.24.71	-	O	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase family M13
HLNKLFDN_00020	8.85e-129	ssb2	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
HLNKLFDN_00021	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HLNKLFDN_00022	0.0	-	-	-	L	-	-	-	PIF1-like helicase
HLNKLFDN_00023	2.61e-210	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HLNKLFDN_00024	3.86e-156	orn	-	-	L	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HLNKLFDN_00025	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HLNKLFDN_00026	1.27e-253	rfe	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 4
HLNKLFDN_00027	2.44e-147	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
HLNKLFDN_00028	8.3e-160	livF	-	-	E	ko:K01995,ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HLNKLFDN_00029	1.19e-192	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
HLNKLFDN_00030	3.09e-249	-	-	-	U	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HLNKLFDN_00031	8.89e-199	-	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HLNKLFDN_00032	6.78e-279	-	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HLNKLFDN_00033	3.12e-221	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HLNKLFDN_00034	4.95e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HLNKLFDN_00035	2.63e-48	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
HLNKLFDN_00037	7.3e-287	xylR	-	-	GK	-	-	-	ROK family
HLNKLFDN_00038	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
HLNKLFDN_00039	5.75e-143	maa	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Bacterial transferase hexapeptide repeat protein
HLNKLFDN_00041	0.0	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	Glycosyl hydrolase family 2, sugar binding domain protein
HLNKLFDN_00042	0.0	-	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HLNKLFDN_00043	4.06e-212	-	-	-	P	ko:K02026,ko:K10119,ko:K17243	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_00044	8.4e-237	-	-	-	U	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_00045	1.22e-309	-	-	-	G	ko:K02027,ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter periplasmic binding protein YcjN precursor K02027
HLNKLFDN_00046	2.05e-233	-	-	-	K	ko:K02529,ko:K17640	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
HLNKLFDN_00047	0.0	-	3.2.1.37, 3.2.1.55	GH43,GH51	G	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HLNKLFDN_00048	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
HLNKLFDN_00049	0.0	-	2.5.1.49	-	H	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.98
HLNKLFDN_00050	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HLNKLFDN_00051	6.09e-139	-	-	-	S	ko:K07149	-	ko00000	Membrane
HLNKLFDN_00052	1.14e-172	-	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
HLNKLFDN_00053	3.94e-114	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HLNKLFDN_00054	3.1e-288	xylR	-	-	GK	-	-	-	ROK family
HLNKLFDN_00055	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
HLNKLFDN_00056	8.24e-217	-	-	-	F	-	-	-	Inosine-uridine preferring nucleoside hydrolase
HLNKLFDN_00057	1.8e-273	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
HLNKLFDN_00058	8.49e-12	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
HLNKLFDN_00059	0.0	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	Glycosyl hydrolase family 2, sugar binding domain protein
HLNKLFDN_00060	3.37e-293	-	3.2.1.156	GH8	G	ko:K15531	-	ko00000,ko01000	CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
HLNKLFDN_00061	0.0	-	-	-	O	-	-	-	Highly conserved protein containing a thioredoxin domain
HLNKLFDN_00062	0.0	-	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HLNKLFDN_00063	0.0	-	-	-	G	-	-	-	Psort location Cytoplasmic, score 8.87
HLNKLFDN_00064	9.32e-193	-	-	-	G	ko:K17328	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_00065	5.2e-225	-	-	-	U	ko:K17327	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_00066	0.0	-	-	-	G	ko:K17326	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter periplasmic binding protein YcjN precursor K02027
HLNKLFDN_00067	1.36e-136	-	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Cytidine and deoxycytidylate deaminase zinc-binding region
HLNKLFDN_00068	2.59e-97	fms	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HLNKLFDN_00069	7.43e-229	-	-	-	V	-	-	-	Beta-lactamase
HLNKLFDN_00070	0.0	yjjK	-	-	S	-	-	-	ATP-binding cassette protein, ChvD family
HLNKLFDN_00071	6.48e-211	tesB	-	-	I	ko:K10805	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	Thioesterase-like superfamily
HLNKLFDN_00072	3.65e-122	-	-	-	S	-	-	-	Protein of unknown function (DUF3180)
HLNKLFDN_00073	0.0	folK	2.7.6.3, 4.1.2.25	-	H	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HLNKLFDN_00074	1.96e-196	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HLNKLFDN_00075	2.51e-150	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
HLNKLFDN_00076	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HLNKLFDN_00077	1.72e-128	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HLNKLFDN_00078	5.05e-258	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HLNKLFDN_00079	0.0	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-Ala-D-Ala carboxypeptidase 3 (S13) family
HLNKLFDN_00080	1.55e-292	-	-	-	M	-	-	-	Glycosyl transferase family 21
HLNKLFDN_00081	0.0	-	-	-	S	-	-	-	AI-2E family transporter
HLNKLFDN_00082	3.15e-230	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HLNKLFDN_00083	1.73e-270	fucO	1.1.1.77, 1.1.99.37, 1.2.98.1	-	C	ko:K00048,ko:K17067	ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
HLNKLFDN_00084	0.0	-	3.1.4.52	-	T	ko:K14051	ko02024,ko02026,map02024,map02026	ko00000,ko00001,ko01000	Putative diguanylate phosphodiesterase
HLNKLFDN_00085	2.54e-144	-	-	-	S	-	-	-	Domain of unknown function (DUF4956)
HLNKLFDN_00086	2.74e-203	-	-	-	P	-	-	-	VTC domain
HLNKLFDN_00087	0.0	-	-	-	M	ko:K06330	-	ko00000	CotH kinase protein
HLNKLFDN_00088	0.0	-	-	-	S	ko:K21012	ko02025,map02025	ko00000,ko00001	Putative exopolysaccharide Exporter (EPS-E)
HLNKLFDN_00089	0.0	-	-	GT4	M	ko:K21011	ko02025,map02025	ko00000,ko00001,ko01003	Domain of unknown function (DUF3492)
HLNKLFDN_00090	0.0	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2194)
HLNKLFDN_00091	4.92e-212	-	-	-	-	-	-	-	-
HLNKLFDN_00092	0.0	-	5.1.3.2	-	GM	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	ADP-glyceromanno-heptose 6-epimerase activity
HLNKLFDN_00096	3.73e-208	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HLNKLFDN_00097	2.47e-253	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HLNKLFDN_00099	1.79e-111	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	low molecular weight
HLNKLFDN_00100	2.42e-166	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dihydrofolate reductase
HLNKLFDN_00101	6.89e-232	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HLNKLFDN_00102	1.07e-94	-	-	-	O	-	-	-	OsmC-like protein
HLNKLFDN_00103	2.53e-241	-	-	-	T	-	-	-	Universal stress protein family
HLNKLFDN_00104	2.31e-121	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
HLNKLFDN_00105	2.43e-212	-	-	-	S	-	-	-	CHAP domain
HLNKLFDN_00106	5.66e-279	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HLNKLFDN_00107	3.36e-55	-	-	-	-	-	-	-	-
HLNKLFDN_00108	1.83e-274	senX3	2.7.13.3	-	T	ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HLNKLFDN_00109	4.77e-130	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HLNKLFDN_00110	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
HLNKLFDN_00111	9.07e-179	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HLNKLFDN_00112	1.86e-267	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
HLNKLFDN_00113	2.99e-125	-	-	-	S	ko:K06889	-	ko00000	Serine aminopeptidase, S33
HLNKLFDN_00114	0.0	-	-	-	G	ko:K03292	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HLNKLFDN_00115	4.3e-247	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HLNKLFDN_00116	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HLNKLFDN_00118	2.9e-275	-	-	-	EGP	ko:K08156,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
HLNKLFDN_00119	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4037)
HLNKLFDN_00120	3.7e-149	-	-	-	S	-	-	-	Protein of unknown function (DUF4125)
HLNKLFDN_00121	2.24e-120	-	-	-	-	-	-	-	-
HLNKLFDN_00122	4.41e-196	pspC	-	-	KT	-	-	-	PspC domain
HLNKLFDN_00123	0.0	tcsS3	-	-	KT	-	-	-	PspC domain
HLNKLFDN_00124	2.9e-157	tcsR3	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HLNKLFDN_00126	4.35e-312	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HLNKLFDN_00127	9.45e-261	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HLNKLFDN_00128	2.41e-244	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.87
HLNKLFDN_00129	3.19e-49	-	-	-	S	-	-	-	Domain of unknown function (DUF5348)
HLNKLFDN_00130	1.74e-101	-	-	-	S	-	-	-	Protein of unknown function (DUF3801)
HLNKLFDN_00131	6.15e-123	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	Psort location Cytoplasmic, score
HLNKLFDN_00132	0.0	-	-	-	L	-	-	-	Domain of unknown function (DUF4368)
HLNKLFDN_00133	3.9e-143	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HLNKLFDN_00134	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	elongation factor G
HLNKLFDN_00135	1.83e-199	arbG	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HLNKLFDN_00136	0.0	ptsG	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system, glucose-specific IIABC component
HLNKLFDN_00137	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
HLNKLFDN_00138	2.42e-194	-	-	-	T	-	-	-	LytTr DNA-binding domain
HLNKLFDN_00139	0.0	-	-	-	T	-	-	-	GHKL domain
HLNKLFDN_00140	7.64e-279	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HLNKLFDN_00141	3.43e-163	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HLNKLFDN_00142	5.05e-07	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
HLNKLFDN_00143	5.44e-139	-	-	-	-	-	-	-	-
HLNKLFDN_00144	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HLNKLFDN_00145	3.95e-275	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin kinase
HLNKLFDN_00146	3.51e-241	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HLNKLFDN_00147	1.9e-98	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HLNKLFDN_00148	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HLNKLFDN_00149	1.21e-242	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HLNKLFDN_00150	1.36e-166	-	-	-	-	-	-	-	-
HLNKLFDN_00152	4.43e-82	gcs2	-	-	S	ko:K06048	-	ko00000,ko01000	A circularly permuted ATPgrasp
HLNKLFDN_00153	2.19e-76	gcs2	-	-	S	ko:K06048	-	ko00000,ko01000	A circularly permuted ATPgrasp
HLNKLFDN_00154	3.16e-233	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HLNKLFDN_00155	1.21e-87	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HLNKLFDN_00156	6.43e-238	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLNKLFDN_00157	1.48e-85	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HLNKLFDN_00158	6.96e-83	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HLNKLFDN_00159	1.47e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HLNKLFDN_00160	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HLNKLFDN_00161	3e-127	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HLNKLFDN_00162	5.9e-314	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HLNKLFDN_00163	5.12e-96	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HLNKLFDN_00164	1.24e-35	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30p/L7e
HLNKLFDN_00165	5.14e-130	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HLNKLFDN_00166	3.75e-77	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HLNKLFDN_00167	5.66e-124	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HLNKLFDN_00168	3.93e-90	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HLNKLFDN_00169	4.1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HLNKLFDN_00170	1.6e-133	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HLNKLFDN_00171	1.81e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HLNKLFDN_00172	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HLNKLFDN_00173	5.52e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HLNKLFDN_00174	1.37e-50	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HLNKLFDN_00175	3.85e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HLNKLFDN_00176	2.74e-147	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HLNKLFDN_00177	5.42e-75	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HLNKLFDN_00178	3.44e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HLNKLFDN_00179	2.71e-195	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HLNKLFDN_00180	8.86e-62	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HLNKLFDN_00181	3.02e-151	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HLNKLFDN_00182	1.64e-151	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HLNKLFDN_00183	5.42e-67	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HLNKLFDN_00184	0.0	adhE	1.1.1.1, 1.2.1.10, 1.2.1.81	-	C	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HLNKLFDN_00185	1.7e-233	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HLNKLFDN_00186	5.19e-251	-	1.1.1.9	-	C	ko:K05351	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
HLNKLFDN_00187	7.11e-304	csbX	-	-	EGP	-	-	-	Major Facilitator Superfamily
HLNKLFDN_00188	3.34e-274	-	-	-	GK	-	-	-	transcriptional repressor of nag (N-acetylglucosamine) operon K02565
HLNKLFDN_00189	2.55e-100	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLNKLFDN_00190	0.0	glgX	3.2.1.196, 3.2.1.68	CBM48,GH13	G	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
HLNKLFDN_00191	1.21e-99	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HLNKLFDN_00192	2.26e-104	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HLNKLFDN_00193	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
HLNKLFDN_00194	1.05e-158	-	-	-	-	-	-	-	-
HLNKLFDN_00195	1.63e-146	yigZ	-	-	S	-	-	-	Uncharacterized protein family UPF0029
HLNKLFDN_00196	7.8e-237	pdxB	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLNKLFDN_00197	0.0	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
HLNKLFDN_00198	1.07e-283	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HLNKLFDN_00200	0.0	-	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
HLNKLFDN_00201	0.0	-	-	-	G	-	-	-	candidate polyfunctional acetylxylan esterase b-xylosidase A-L-arabinofuranosidase, CBM9 module, glycoside hydrolase family 43 protein and carbohydrate esterase family 6 protein K01238
HLNKLFDN_00202	1.37e-299	-	3.2.1.156	GH8	G	ko:K15531	-	ko00000,ko01000	CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
HLNKLFDN_00203	0.0	-	-	-	G	-	-	-	Psort location Cytoplasmic, score 8.87
HLNKLFDN_00204	0.0	-	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HLNKLFDN_00205	1.82e-195	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLNKLFDN_00206	8.75e-200	-	-	-	EP	ko:K02031,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HLNKLFDN_00207	3.26e-179	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_00208	2.8e-231	-	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_00209	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HLNKLFDN_00211	2.81e-260	dapC	-	-	E	-	-	-	Aminotransferase class I and II
HLNKLFDN_00212	2.61e-78	fdxA	-	-	C	ko:K05524	-	ko00000	4Fe-4S binding domain
HLNKLFDN_00213	0.0	-	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
HLNKLFDN_00214	5.77e-268	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HLNKLFDN_00215	7.79e-35	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
HLNKLFDN_00219	3.49e-63	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HLNKLFDN_00220	1.54e-217	-	-	-	-	-	-	-	-
HLNKLFDN_00221	1.46e-144	rimJ	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HLNKLFDN_00222	6.22e-129	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
HLNKLFDN_00223	2.78e-41	-	-	-	S	-	-	-	Putative regulatory protein
HLNKLFDN_00224	3.71e-117	-	-	-	NO	-	-	-	SAF
HLNKLFDN_00225	1.18e-48	-	-	-	-	-	-	-	-
HLNKLFDN_00226	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
HLNKLFDN_00227	1.87e-232	-	-	-	T	-	-	-	Forkhead associated domain
HLNKLFDN_00228	5.66e-69	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HLNKLFDN_00229	5.91e-114	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HLNKLFDN_00230	9.45e-315	-	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
HLNKLFDN_00231	9.44e-186	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
HLNKLFDN_00232	6.41e-190	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HLNKLFDN_00233	1.92e-218	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
HLNKLFDN_00234	4.3e-208	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HLNKLFDN_00235	1.75e-255	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import
HLNKLFDN_00236	2.31e-166	regX3	-	-	KT	ko:K07776	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HLNKLFDN_00237	6.84e-279	phoR	2.7.13.3	-	T	ko:K07636,ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HLNKLFDN_00238	5.18e-159	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HLNKLFDN_00239	2.39e-280	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HLNKLFDN_00240	7.32e-269	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HLNKLFDN_00241	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HLNKLFDN_00242	3.35e-148	-	-	-	D	-	-	-	nuclear chromosome segregation
HLNKLFDN_00243	8.36e-162	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HLNKLFDN_00244	7.53e-185	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HLNKLFDN_00245	8.07e-235	yfiH	-	-	Q	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
HLNKLFDN_00246	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32 C-terminal domain
HLNKLFDN_00247	1.53e-217	-	-	-	C	-	-	-	Oxidoreductase, aldo keto reductase family protein
HLNKLFDN_00248	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HLNKLFDN_00249	2.09e-118	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HLNKLFDN_00250	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HLNKLFDN_00251	2.04e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HLNKLFDN_00252	6.58e-152	-	-	-	-	-	-	-	-
HLNKLFDN_00254	0.0	ams	2.4.1.4	GH13	G	ko:K05341	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HLNKLFDN_00255	7.23e-107	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HLNKLFDN_00257	0.0	fas	-	-	I	ko:K11533	ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931	ko00000,ko00001,ko00002,ko01000,ko01004	Beta-ketoacyl synthase, C-terminal domain
HLNKLFDN_00258	0.0	pccB	-	-	I	-	-	-	Carboxyl transferase domain
HLNKLFDN_00259	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase L chain, ATP binding domain protein
HLNKLFDN_00260	9.8e-117	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HLNKLFDN_00261	6.21e-207	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
HLNKLFDN_00262	0.0	-	-	-	-	-	-	-	-
HLNKLFDN_00263	4.85e-185	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HLNKLFDN_00264	1.18e-157	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HLNKLFDN_00265	5.21e-95	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HLNKLFDN_00266	6.24e-175	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HLNKLFDN_00267	3.48e-44	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HLNKLFDN_00269	9.46e-296	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
HLNKLFDN_00270	3.06e-261	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HLNKLFDN_00271	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HLNKLFDN_00272	3.53e-52	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
HLNKLFDN_00273	1.19e-61	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HLNKLFDN_00274	0.0	rne	3.1.26.12	-	J	ko:K08300,ko:K08301	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	Ribonuclease E/G family
HLNKLFDN_00275	1.37e-292	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
HLNKLFDN_00276	3.73e-212	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HLNKLFDN_00277	0.0	-	-	-	V	-	-	-	Efflux ABC transporter, permease protein
HLNKLFDN_00278	1.13e-165	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HLNKLFDN_00279	8.62e-165	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HLNKLFDN_00280	2.22e-148	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HLNKLFDN_00281	2.89e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HLNKLFDN_00282	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HLNKLFDN_00283	4.82e-230	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
HLNKLFDN_00286	5.31e-134	-	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Psort location Cytoplasmic, score 8.87
HLNKLFDN_00287	6.1e-143	-	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Psort location Cytoplasmic, score 8.87
HLNKLFDN_00288	1.31e-303	-	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Psort location Cytoplasmic, score 8.87
HLNKLFDN_00289	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HLNKLFDN_00290	1.18e-178	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HLNKLFDN_00291	2.39e-154	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HLNKLFDN_00292	4.99e-101	-	-	-	K	-	-	-	MerR, DNA binding
HLNKLFDN_00293	6.86e-249	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
HLNKLFDN_00294	1.02e-76	-	-	-	S	-	-	-	Protein of unknown function (DUF3039)
HLNKLFDN_00295	6.03e-114	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HLNKLFDN_00296	8.17e-169	-	-	-	-	-	-	-	-
HLNKLFDN_00297	6.94e-146	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HLNKLFDN_00298	2.33e-35	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HLNKLFDN_00299	2.43e-177	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HLNKLFDN_00300	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
HLNKLFDN_00301	1.54e-118	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
HLNKLFDN_00302	5.66e-313	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HLNKLFDN_00304	1.56e-121	-	-	-	-	-	-	-	-
HLNKLFDN_00305	0.0	yjjK	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter
HLNKLFDN_00306	1.82e-190	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase C26
HLNKLFDN_00307	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HLNKLFDN_00308	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HLNKLFDN_00309	1.18e-230	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
HLNKLFDN_00310	3.81e-74	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HLNKLFDN_00311	5.05e-47	-	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HLNKLFDN_00312	2.18e-138	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HLNKLFDN_00313	3.28e-198	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HLNKLFDN_00314	1.52e-136	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Conserved hypothetical protein 95
HLNKLFDN_00315	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	helicase superfamily c-terminal domain
HLNKLFDN_00316	1.82e-41	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
HLNKLFDN_00317	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HLNKLFDN_00318	2.02e-305	-	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HLNKLFDN_00319	1.01e-165	gntR	-	-	K	-	-	-	FCD
HLNKLFDN_00320	1.56e-105	gntK	2.7.1.12	-	F	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Shikimate kinase
HLNKLFDN_00321	5.57e-290	gnuT	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
HLNKLFDN_00323	1.66e-211	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase, C-terminal domain
HLNKLFDN_00324	6.82e-295	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
HLNKLFDN_00325	7.45e-158	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLNKLFDN_00326	8.89e-289	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HLNKLFDN_00327	7.95e-291	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HLNKLFDN_00328	1.96e-177	-	-	-	M	-	-	-	Mechanosensitive ion channel
HLNKLFDN_00329	1.88e-220	-	-	-	S	-	-	-	CAAX protease self-immunity
HLNKLFDN_00330	4.48e-278	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HLNKLFDN_00331	1.31e-228	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
HLNKLFDN_00332	6.04e-226	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HLNKLFDN_00333	0.0	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HLNKLFDN_00334	6.6e-259	pyr	1.3.98.1	-	F	ko:K00226	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
HLNKLFDN_00335	2.68e-169	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HLNKLFDN_00336	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HLNKLFDN_00337	1.9e-180	ltbR	-	-	K	-	-	-	Transcriptional regulator, IclR family, C-terminal domain protein
HLNKLFDN_00338	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HLNKLFDN_00341	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HLNKLFDN_00342	8.31e-193	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HLNKLFDN_00343	1.86e-242	-	-	-	-	-	-	-	-
HLNKLFDN_00344	1.02e-157	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HLNKLFDN_00345	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HLNKLFDN_00346	4.49e-125	-	-	-	S	-	-	-	GtrA-like protein
HLNKLFDN_00347	2.72e-82	-	-	-	S	-	-	-	Macrophage migration inhibitory factor (MIF)
HLNKLFDN_00348	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate-tetrahydrofolate ligase
HLNKLFDN_00349	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
HLNKLFDN_00350	5.02e-139	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HLNKLFDN_00351	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HLNKLFDN_00352	1.53e-52	hpr	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
HLNKLFDN_00353	6.89e-235	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HLNKLFDN_00354	1.72e-250	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HLNKLFDN_00355	5.09e-132	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HLNKLFDN_00356	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HLNKLFDN_00357	3.21e-254	-	-	-	I	-	-	-	PAP2 superfamily
HLNKLFDN_00358	4.39e-289	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HLNKLFDN_00359	4.28e-274	ino1	5.5.1.4	-	I	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	ko00000,ko00001,ko01000	Myo-inositol-1-phosphate synthase
HLNKLFDN_00360	0.0	pbp5	-	-	M	-	-	-	Transglycosylase
HLNKLFDN_00361	0.0	-	-	-	S	ko:K09955	-	ko00000	Beta-L-arabinofuranosidase, GH127
HLNKLFDN_00362	1.24e-204	-	-	-	U	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_00363	1.46e-214	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_00364	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HLNKLFDN_00365	8.04e-260	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HLNKLFDN_00366	9.31e-251	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HLNKLFDN_00367	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HLNKLFDN_00368	0.0	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	C-terminal of Glycosyl hydrolases family 43
HLNKLFDN_00369	0.0	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	C-terminal of Glycosyl hydrolases family 43
HLNKLFDN_00370	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HLNKLFDN_00371	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HLNKLFDN_00372	8.81e-148	-	-	-	-	-	-	-	-
HLNKLFDN_00374	1.41e-264	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HLNKLFDN_00375	1.17e-125	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
HLNKLFDN_00376	7.1e-175	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HLNKLFDN_00377	7.53e-137	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HLNKLFDN_00378	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III subunit gamma tau
HLNKLFDN_00379	1.57e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLNKLFDN_00380	6.25e-247	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HLNKLFDN_00381	1.59e-269	-	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Diacylglycerol kinase catalytic domain protein
HLNKLFDN_00382	1.6e-71	-	-	-	S	-	-	-	TIGRFAM helicase secretion neighborhood TadE-like protein
HLNKLFDN_00383	2.1e-78	-	-	-	U	-	-	-	TadE-like protein
HLNKLFDN_00384	3.15e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF4244)
HLNKLFDN_00385	1.34e-115	-	-	-	NU	-	-	-	Type II secretion system (T2SS), protein F
HLNKLFDN_00386	1.75e-161	-	-	-	U	ko:K12510	-	ko00000,ko02044	Type ii secretion system
HLNKLFDN_00387	9.44e-234	cpaF	-	-	U	ko:K02283	-	ko00000,ko02035,ko02044	Type II IV secretion system protein
HLNKLFDN_00388	6.13e-182	-	-	-	D	-	-	-	bacterial-type flagellum organization
HLNKLFDN_00389	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HLNKLFDN_00390	1.08e-287	mutT	3.6.1.55	-	LT	ko:K03574	-	ko00000,ko01000,ko03400	Phosphoglycerate mutase family
HLNKLFDN_00391	8.12e-134	-	-	-	-	-	-	-	-
HLNKLFDN_00392	1.64e-151	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HLNKLFDN_00393	9.35e-263	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HLNKLFDN_00394	0.0	-	-	-	G	-	-	-	Bacterial Ig-like domain (group 4)
HLNKLFDN_00395	0.0	-	3.2.1.187	GH121	DG	ko:K18206	-	ko00000,ko01000	Bacterial Ig-like domain (group 4)
HLNKLFDN_00396	0.0	-	3.2.1.185	GH127	S	ko:K09955,ko:K18205	-	ko00000,ko01000	Beta-L-arabinofuranosidase, GH127
HLNKLFDN_00397	3.39e-187	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_00398	5.95e-214	-	-	-	P	ko:K02025,ko:K10189	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_00399	5.38e-316	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HLNKLFDN_00400	1.31e-245	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein domain
HLNKLFDN_00401	0.0	-	-	-	S	ko:K03688	-	ko00000	ABC1 family
HLNKLFDN_00402	4.06e-42	-	-	-	S	-	-	-	granule-associated protein
HLNKLFDN_00403	1.61e-175	cobQ2	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
HLNKLFDN_00404	0.0	murE	-	-	M	-	-	-	Domain of unknown function (DUF1727)
HLNKLFDN_00405	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HLNKLFDN_00406	0.0	glnD	2.7.7.59	-	O	ko:K00990	ko02020,map02020	ko00000,ko00001,ko01000	Nucleotidyltransferase domain
HLNKLFDN_00407	8.92e-73	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Nitrogen regulatory protein P-II
HLNKLFDN_00408	1.45e-302	amt	-	-	U	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
HLNKLFDN_00409	2.03e-251	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HLNKLFDN_00410	3.13e-148	icaR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLNKLFDN_00411	2.28e-248	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyltransferase like family 2
HLNKLFDN_00412	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
HLNKLFDN_00414	7.09e-29	-	-	-	M	-	-	-	cell wall binding repeat
HLNKLFDN_00415	9.71e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HLNKLFDN_00416	1.22e-288	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HLNKLFDN_00417	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HLNKLFDN_00418	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HLNKLFDN_00419	2.62e-118	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
HLNKLFDN_00420	4.79e-103	-	-	-	S	-	-	-	FMN_bind
HLNKLFDN_00421	3.98e-191	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLNKLFDN_00422	1.91e-267	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HLNKLFDN_00424	8.44e-288	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HLNKLFDN_00425	1.42e-287	-	-	-	S	-	-	-	Predicted membrane protein (DUF2318)
HLNKLFDN_00426	9.48e-134	-	-	-	P	ko:K07230	-	ko00000,ko02000	Fe2+ transport protein
HLNKLFDN_00427	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	Iron permease FTR1 family
HLNKLFDN_00428	4.71e-302	-	-	-	G	-	-	-	MFS/sugar transport protein
HLNKLFDN_00429	1.33e-144	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HLNKLFDN_00430	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HLNKLFDN_00431	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HLNKLFDN_00432	3.21e-75	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HLNKLFDN_00433	9.2e-197	-	-	-	C	-	-	-	Aldo/keto reductase family
HLNKLFDN_00434	6.92e-37	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	ThiS family
HLNKLFDN_00435	2.91e-166	thiF	2.7.7.73	-	H	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
HLNKLFDN_00436	1.79e-214	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HLNKLFDN_00437	0.0	-	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HLNKLFDN_00438	7.59e-114	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HLNKLFDN_00439	0.0	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
HLNKLFDN_00440	0.0	-	-	-	M	-	-	-	domain protein
HLNKLFDN_00441	2.61e-234	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HLNKLFDN_00442	1.4e-100	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HLNKLFDN_00443	8.29e-304	-	-	-	P	-	-	-	Sodium/hydrogen exchanger family
HLNKLFDN_00444	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HLNKLFDN_00445	0.0	aroP	-	-	E	ko:K03293,ko:K11732	-	ko00000,ko02000	aromatic amino acid transport protein AroP K03293
HLNKLFDN_00446	4.27e-16	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HLNKLFDN_00447	1.15e-237	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HLNKLFDN_00448	3.36e-46	-	3.2.1.25	-	G	ko:K01192	ko00511,ko04142,map00511,map04142	ko00000,ko00001,ko01000	beta-mannosidase
HLNKLFDN_00449	0.0	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
HLNKLFDN_00450	3.55e-258	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HLNKLFDN_00451	2.65e-259	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HLNKLFDN_00452	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
HLNKLFDN_00453	0.0	scrT	-	-	G	-	-	-	Transporter major facilitator family protein
HLNKLFDN_00454	5.21e-193	-	-	-	P	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_00455	4.35e-210	-	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_00456	7.47e-297	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HLNKLFDN_00457	0.0	-	2.4.1.4, 3.2.1.1, 3.2.1.20, 5.4.99.16	GH13,GH31	G	ko:K01187,ko:K05341,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
HLNKLFDN_00458	9.01e-147	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HLNKLFDN_00459	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Domain of unknown function (DUF1964)
HLNKLFDN_00460	5.83e-251	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HLNKLFDN_00461	9.84e-41	livK	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HLNKLFDN_00462	5.18e-81	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLNKLFDN_00463	1.03e-196	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLNKLFDN_00464	3.05e-136	-	-	-	L	-	-	-	Transposase and inactivated derivatives
HLNKLFDN_00465	9.59e-39	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HLNKLFDN_00466	1.39e-195	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
HLNKLFDN_00467	9.01e-314	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HLNKLFDN_00468	1.75e-261	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HLNKLFDN_00469	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HLNKLFDN_00470	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HLNKLFDN_00471	4.95e-219	-	-	-	EG	-	-	-	EamA-like transporter family
HLNKLFDN_00472	1.33e-237	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HLNKLFDN_00474	2.68e-254	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HLNKLFDN_00475	0.0	fprA	1.18.1.2, 1.19.1.1	-	C	ko:K00528	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase
HLNKLFDN_00476	0.0	-	-	-	E	ko:K11738	-	ko00000,ko02000	aromatic amino acid transport protein AroP K03293
HLNKLFDN_00477	1.58e-240	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HLNKLFDN_00478	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HLNKLFDN_00479	0.0	degP	-	-	O	ko:K08372	ko02020,map02020	ko00000,ko00001,ko01000,ko01002	Domain present in PSD-95, Dlg, and ZO-1/2.
HLNKLFDN_00480	0.0	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HLNKLFDN_00483	3.04e-213	-	-	-	EG	-	-	-	EamA-like transporter family
HLNKLFDN_00484	2.35e-246	pldB	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Serine aminopeptidase, S33
HLNKLFDN_00485	6.6e-147	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HLNKLFDN_00486	1.27e-291	-	-	-	T	-	-	-	Histidine kinase
HLNKLFDN_00487	0.0	pepX	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Dipeptidyl peptidase IV (DPP IV) N-terminal region
HLNKLFDN_00488	2.6e-168	fhaA	-	-	T	-	-	-	Protein of unknown function (DUF2662)
HLNKLFDN_00489	1.57e-108	fhaB	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
HLNKLFDN_00490	0.0	pstP	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
HLNKLFDN_00491	0.0	rodA	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HLNKLFDN_00492	0.0	pbpA	-	-	M	ko:K05364	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
HLNKLFDN_00493	4.29e-227	pknA	2.7.11.1	-	T	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HLNKLFDN_00494	0.0	pknB	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HLNKLFDN_00495	9.45e-154	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	para-aminobenzoate synthase glutamine amidotransferase component II
HLNKLFDN_00496	2.74e-266	srtB	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HLNKLFDN_00497	1.12e-182	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
HLNKLFDN_00498	2.28e-90	crgA	-	-	D	-	-	-	Involved in cell division
HLNKLFDN_00499	7.92e-307	-	-	-	L	-	-	-	ribosomal rna small subunit methyltransferase
HLNKLFDN_00500	5.46e-189	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
HLNKLFDN_00501	1.33e-47	-	-	-	-	-	-	-	-
HLNKLFDN_00502	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HLNKLFDN_00503	6.39e-82	-	-	-	I	-	-	-	Sterol carrier protein
HLNKLFDN_00504	6.07e-64	-	-	-	S	-	-	-	Protein of unknown function (DUF3073)
HLNKLFDN_00505	7.56e-262	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HLNKLFDN_00506	0.0	-	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HLNKLFDN_00507	0.0	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HLNKLFDN_00508	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HLNKLFDN_00509	4.67e-49	-	-	-	-	-	-	-	-
HLNKLFDN_00511	9.64e-153	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HLNKLFDN_00512	3.75e-303	-	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
HLNKLFDN_00513	2.31e-239	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HLNKLFDN_00514	3.41e-142	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
HLNKLFDN_00518	2.21e-97	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HLNKLFDN_00519	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HLNKLFDN_00520	5.13e-106	-	-	-	S	-	-	-	Transmembrane domain of unknown function (DUF3566)
HLNKLFDN_00521	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLNKLFDN_00522	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLNKLFDN_00523	1.01e-115	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
HLNKLFDN_00524	6.39e-298	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HLNKLFDN_00525	8.94e-260	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HLNKLFDN_00526	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HLNKLFDN_00527	2.68e-19	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HLNKLFDN_00528	6.11e-233	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
HLNKLFDN_00529	2.6e-118	jag	-	-	S	ko:K06346	-	ko00000	Putative single-stranded nucleic acids-binding domain
HLNKLFDN_00530	2.69e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HLNKLFDN_00531	3.04e-221	parA	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
HLNKLFDN_00532	1.49e-271	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HLNKLFDN_00533	9.04e-220	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HLNKLFDN_00534	1.6e-19	-	-	-	S	-	-	-	Psort location Extracellular, score 8.82
HLNKLFDN_00536	1.52e-155	-	-	-	S	-	-	-	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
HLNKLFDN_00537	1.75e-15	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HLNKLFDN_00538	0.0	-	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
HLNKLFDN_00539	0.0	mviN	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
HLNKLFDN_00540	0.0	-	-	-	M	-	-	-	Conserved repeat domain
HLNKLFDN_00541	6.34e-156	mutT4	-	-	L	-	-	-	Belongs to the Nudix hydrolase family
HLNKLFDN_00542	0.0	pcnA	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Probable RNA and SrmB- binding site of polymerase A
HLNKLFDN_00543	8.42e-142	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
HLNKLFDN_00544	6.24e-214	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HLNKLFDN_00545	2.46e-219	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HLNKLFDN_00546	9.28e-254	rpfB	-	-	S	ko:K21688	-	ko00000	G5
HLNKLFDN_00548	2.31e-213	-	-	-	O	-	-	-	Thioredoxin
HLNKLFDN_00549	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HLNKLFDN_00550	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
HLNKLFDN_00551	2.99e-144	dcd	3.5.4.13	-	F	ko:K01494	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dCTP deaminase family
HLNKLFDN_00552	1.99e-197	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
HLNKLFDN_00553	0.0	nhaP	-	-	P	ko:K03316	-	ko00000	Sodium/hydrogen exchanger family
HLNKLFDN_00554	2.32e-100	tadA	3.5.4.1, 3.5.4.33	-	FJ	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HLNKLFDN_00555	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
HLNKLFDN_00556	5.18e-295	-	-	-	GK	-	-	-	ROK family
HLNKLFDN_00557	6.1e-313	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HLNKLFDN_00558	2.9e-203	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_00559	1.51e-198	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_00560	0.0	-	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HLNKLFDN_00561	1.76e-296	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HLNKLFDN_00562	1.62e-184	cobB2	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
HLNKLFDN_00563	6e-74	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HLNKLFDN_00564	1.29e-103	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HLNKLFDN_00565	4.16e-93	-	-	-	-	ko:K03646	-	ko00000,ko02000	-
HLNKLFDN_00567	2.67e-88	-	-	-	S	-	-	-	Pfam:CtkA_N
HLNKLFDN_00569	2.16e-128	-	-	-	-	-	-	-	-
HLNKLFDN_00570	3.42e-34	-	-	-	-	-	-	-	-
HLNKLFDN_00574	5.43e-55	-	-	-	-	-	-	-	-
HLNKLFDN_00575	8.54e-263	-	-	-	-	-	-	-	-
HLNKLFDN_00578	0.0	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HLNKLFDN_00579	1.05e-65	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HLNKLFDN_00580	3.56e-133	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HLNKLFDN_00581	0.0	-	-	-	D	-	-	-	Cell surface antigen C-terminus
HLNKLFDN_00582	5.7e-127	-	-	-	M	-	-	-	domain protein
HLNKLFDN_00583	3.83e-13	-	-	-	S	-	-	-	Leucine rich repeats (6 copies)
HLNKLFDN_00584	1.48e-87	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HLNKLFDN_00585	2.27e-24	-	-	-	D	-	-	-	nuclear chromosome segregation
HLNKLFDN_00588	0.0	-	-	-	U	-	-	-	Type IV secretory pathway, VirB4
HLNKLFDN_00589	0.0	-	-	-	U	-	-	-	TraM recognition site of TraD and TraG
HLNKLFDN_00595	2.38e-99	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
HLNKLFDN_00596	0.0	-	-	-	V	-	-	-	N-6 DNA Methylase
HLNKLFDN_00597	2.99e-107	-	-	-	L	-	-	-	Resolvase, N terminal domain
HLNKLFDN_00599	6.16e-77	-	-	-	V	-	-	-	Psort location Cytoplasmic, score
HLNKLFDN_00600	4.28e-49	-	-	-	-	-	-	-	-
HLNKLFDN_00602	1.08e-54	-	-	-	-	-	-	-	-
HLNKLFDN_00604	1.17e-111	-	-	-	-	-	-	-	-
HLNKLFDN_00606	0.0	-	-	-	KL	-	-	-	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HLNKLFDN_00609	3.23e-22	-	-	-	-	-	-	-	-
HLNKLFDN_00611	4.92e-244	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	DNA topoisomerase
HLNKLFDN_00613	5.08e-95	-	-	-	D	-	-	-	nucleotidyltransferase activity
HLNKLFDN_00614	2.52e-48	-	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
HLNKLFDN_00615	3.62e-42	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HLNKLFDN_00616	5.7e-43	-	-	-	-	-	-	-	-
HLNKLFDN_00617	0.0	-	-	-	L	-	-	-	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HLNKLFDN_00619	1.66e-123	-	-	-	-	-	-	-	-
HLNKLFDN_00620	3.25e-38	-	-	-	S	-	-	-	Fic/DOC family
HLNKLFDN_00621	5.2e-71	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	single-stranded DNA binding
HLNKLFDN_00623	1.1e-125	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease, DNA polymerase III, epsilon subunit family
HLNKLFDN_00624	6.52e-122	-	-	-	S	-	-	-	Protein of unknown function (DUF2786)
HLNKLFDN_00626	1.32e-50	-	-	-	DJ	ko:K06218	-	ko00000,ko02048	Addiction module toxin, RelE StbE family
HLNKLFDN_00627	7.2e-35	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HLNKLFDN_00630	2.02e-31	-	-	-	S	-	-	-	Domain of unknown function (DUF3846)
HLNKLFDN_00633	5.16e-29	-	-	-	-	-	-	-	-
HLNKLFDN_00636	4.12e-05	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HLNKLFDN_00637	1.06e-175	-	3.6.4.12	-	F	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RecQ zinc-binding
HLNKLFDN_00639	4.4e-28	-	-	-	-	-	-	-	-
HLNKLFDN_00641	6.21e-100	-	-	-	L	-	-	-	helicase
HLNKLFDN_00643	8.18e-13	-	-	-	-	-	-	-	-
HLNKLFDN_00654	7.44e-26	-	-	-	-	-	-	-	-
HLNKLFDN_00655	8.45e-226	intA	-	-	L	-	-	-	Phage integrase family
HLNKLFDN_00657	5.36e-71	-	-	-	S	-	-	-	Helix-turn-helix domain
HLNKLFDN_00662	9.91e-88	ydhQ	2.7.11.1	-	MU	ko:K12132	-	ko00000,ko01000,ko01001	cell adhesion
HLNKLFDN_00666	2.76e-240	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HLNKLFDN_00667	7.45e-179	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HLNKLFDN_00668	5.54e-131	-	-	-	-	-	-	-	-
HLNKLFDN_00669	9.69e-309	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HLNKLFDN_00670	0.0	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HLNKLFDN_00671	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase N terminus
HLNKLFDN_00672	4.16e-297	-	-	-	EGP	-	-	-	Transporter major facilitator family protein
HLNKLFDN_00673	1.49e-138	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
HLNKLFDN_00674	1.96e-222	-	-	-	G	-	-	-	Fic/DOC family
HLNKLFDN_00675	7.82e-182	-	-	-	-	-	-	-	-
HLNKLFDN_00676	8.18e-208	-	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
HLNKLFDN_00677	3.09e-215	-	-	-	S	-	-	-	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HLNKLFDN_00678	2.33e-98	-	3.4.13.22	-	S	ko:K08641,ko:K11206	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HLNKLFDN_00679	2.31e-122	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Redoxin
HLNKLFDN_00680	5.7e-06	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
HLNKLFDN_00681	1.04e-122	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
HLNKLFDN_00682	0.0	-	-	-	S	-	-	-	Histidine phosphatase superfamily (branch 2)
HLNKLFDN_00683	2.28e-59	-	-	-	L	-	-	-	transposition
HLNKLFDN_00684	2.66e-31	-	-	-	C	-	-	-	Acetamidase/Formamidase family
HLNKLFDN_00685	5.29e-78	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HLNKLFDN_00686	1.13e-220	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HLNKLFDN_00687	1.08e-157	-	-	-	S	-	-	-	ABC-2 family transporter protein
HLNKLFDN_00688	1.24e-158	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HLNKLFDN_00689	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HLNKLFDN_00690	2.71e-228	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HLNKLFDN_00691	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
HLNKLFDN_00692	1.25e-150	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
HLNKLFDN_00693	5.6e-172	tlyA	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HLNKLFDN_00694	1.19e-236	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
HLNKLFDN_00695	2.4e-226	-	-	-	L	-	-	-	Tetratricopeptide repeat
HLNKLFDN_00696	7.41e-312	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HLNKLFDN_00697	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HLNKLFDN_00698	1.6e-178	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HLNKLFDN_00699	2.36e-122	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HLNKLFDN_00700	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HLNKLFDN_00701	4.33e-303	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HLNKLFDN_00702	3.29e-110	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HLNKLFDN_00703	2.32e-235	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HLNKLFDN_00704	5.56e-305	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HLNKLFDN_00705	5.02e-228	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HLNKLFDN_00706	1.19e-260	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HLNKLFDN_00707	6.69e-263	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HLNKLFDN_00708	7.69e-148	-	-	-	-	-	-	-	-
HLNKLFDN_00709	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Phenylalanyl-tRNA synthetase beta
HLNKLFDN_00710	2.61e-260	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HLNKLFDN_00711	5.63e-195	tsnR	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLNKLFDN_00712	1.38e-120	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Possible lysine decarboxylase
HLNKLFDN_00713	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HLNKLFDN_00714	5.03e-183	-	-	-	S	-	-	-	Domain of unknown function (DUF4191)
HLNKLFDN_00715	1.83e-314	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HLNKLFDN_00716	4.09e-127	-	-	-	S	-	-	-	Protein of unknown function (DUF3043)
HLNKLFDN_00717	0.0	argE	-	-	E	-	-	-	Peptidase dimerisation domain
HLNKLFDN_00718	1.27e-186	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HLNKLFDN_00719	0.0	ykoD	-	-	P	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HLNKLFDN_00720	2.28e-110	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HLNKLFDN_00721	4.1e-272	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HLNKLFDN_00722	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HLNKLFDN_00723	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HLNKLFDN_00724	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HLNKLFDN_00725	0.0	-	2.8.2.22	-	S	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
HLNKLFDN_00726	6.33e-186	-	-	-	P	ko:K16784	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HLNKLFDN_00727	2.89e-281	-	-	-	E	-	-	-	Aminotransferase class I and II
HLNKLFDN_00728	3.28e-181	ppgK	2.7.1.2, 2.7.1.63	-	GK	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HLNKLFDN_00729	1.48e-253	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
HLNKLFDN_00731	9.1e-188	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HLNKLFDN_00732	3.73e-63	-	-	-	J	ko:K07574	-	ko00000,ko03009	CRS1_YhbY
HLNKLFDN_00733	0.0	-	-	-	GP	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLNKLFDN_00734	1.56e-122	-	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HLNKLFDN_00735	0.0	-	-	-	KL	-	-	-	Psort location Cytoplasmic, score 8.87
HLNKLFDN_00736	4.94e-149	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
HLNKLFDN_00737	3.41e-232	-	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HLNKLFDN_00738	1.09e-109	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HLNKLFDN_00739	1.79e-159	-	-	-	S	-	-	-	alpha beta
HLNKLFDN_00741	1.86e-38	-	-	-	S	-	-	-	Protein of unknown function DUF262
HLNKLFDN_00742	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
HLNKLFDN_00743	0.0	-	-	-	S	ko:K06915	-	ko00000	AAA-like domain
HLNKLFDN_00744	2.03e-68	-	-	-	S	-	-	-	SIR2-like domain
HLNKLFDN_00745	3.16e-235	-	-	-	V	-	-	-	Type III restriction enzyme res subunit
HLNKLFDN_00746	1.92e-238	-	-	-	L	-	-	-	Eco57I restriction-modification methylase
HLNKLFDN_00747	0.0	-	-	-	KL	-	-	-	Type III restriction enzyme res subunit
HLNKLFDN_00748	1.03e-173	-	-	-	-	-	-	-	-
HLNKLFDN_00749	2.36e-55	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative DNA-binding domain
HLNKLFDN_00750	2.94e-85	-	-	-	S	-	-	-	Putative inner membrane protein (DUF1819)
HLNKLFDN_00751	7.71e-32	-	-	-	-	-	-	-	-
HLNKLFDN_00752	6.71e-92	-	-	-	-	-	-	-	-
HLNKLFDN_00753	7.25e-270	-	-	-	-	-	-	-	-
HLNKLFDN_00754	1.03e-191	-	-	-	S	-	-	-	phosphoesterase or phosphohydrolase
HLNKLFDN_00755	6.26e-53	-	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HLNKLFDN_00756	6.8e-104	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin domain
HLNKLFDN_00757	1.16e-211	-	1.1.1.91	-	C	ko:K05882	-	ko00000,ko01000	Aldo/keto reductase family
HLNKLFDN_00758	1.61e-163	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
HLNKLFDN_00759	4.21e-171	-	-	-	S	-	-	-	DUF218 domain
HLNKLFDN_00760	4.9e-301	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HLNKLFDN_00761	1.7e-299	rnd	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
HLNKLFDN_00762	3.3e-102	-	-	-	S	-	-	-	Protein of unknown function (DUF3000)
HLNKLFDN_00763	1.76e-210	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HLNKLFDN_00764	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HLNKLFDN_00765	1.28e-41	-	-	-	-	-	-	-	-
HLNKLFDN_00766	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HLNKLFDN_00767	1.07e-284	-	-	-	S	-	-	-	Peptidase dimerisation domain
HLNKLFDN_00768	1.35e-199	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HLNKLFDN_00769	9e-192	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
HLNKLFDN_00770	2.91e-188	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HLNKLFDN_00771	1.59e-144	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_00772	1.52e-98	-	-	-	-	-	-	-	-
HLNKLFDN_00773	2.04e-128	-	-	-	V	-	-	-	Abi-like protein
HLNKLFDN_00774	3.72e-42	-	-	-	L	-	-	-	Helix-turn-helix domain
HLNKLFDN_00775	0.0	-	-	-	S	-	-	-	LPXTG-motif cell wall anchor domain protein
HLNKLFDN_00776	4.15e-312	dinF	-	-	V	-	-	-	MatE
HLNKLFDN_00777	7.75e-130	ppiA	5.2.1.8	-	G	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HLNKLFDN_00778	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HLNKLFDN_00779	5.02e-110	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HLNKLFDN_00780	8.5e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4193)
HLNKLFDN_00781	3.91e-228	-	-	-	S	-	-	-	Protein of unknown function (DUF3071)
HLNKLFDN_00782	1.45e-299	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
HLNKLFDN_00783	0.0	gyrA2	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
HLNKLFDN_00784	0.0	lhr	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
HLNKLFDN_00785	6.21e-43	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HLNKLFDN_00786	7.86e-103	-	-	-	S	-	-	-	Protein of unknown function (DUF2975)
HLNKLFDN_00787	7.7e-310	-	-	-	T	-	-	-	Domain of unknown function (DUF4173)
HLNKLFDN_00788	4.22e-287	-	-	-	G	-	-	-	Major Facilitator Superfamily
HLNKLFDN_00789	0.0	gyrB2	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
HLNKLFDN_00790	3.32e-226	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HLNKLFDN_00791	3.03e-70	-	-	-	-	-	-	-	-
HLNKLFDN_00792	1.89e-50	-	-	-	-	-	-	-	-
HLNKLFDN_00793	2.11e-250	idsA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HLNKLFDN_00794	0.0	pknL	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	PASTA
HLNKLFDN_00795	3.04e-171	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HLNKLFDN_00796	4.49e-129	-	-	-	-	-	-	-	-
HLNKLFDN_00797	1.53e-245	trpD	2.4.2.18	-	F	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HLNKLFDN_00798	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HLNKLFDN_00799	5.45e-153	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HLNKLFDN_00800	2.42e-83	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
HLNKLFDN_00801	4.08e-270	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HLNKLFDN_00802	2.37e-59	-	-	-	S	-	-	-	Protein of unknown function (DUF3046)
HLNKLFDN_00803	2.22e-103	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HLNKLFDN_00804	4.76e-125	cinA	3.5.1.42	-	S	ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HLNKLFDN_00805	1.44e-156	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HLNKLFDN_00806	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE family protein
HLNKLFDN_00807	3.76e-245	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HLNKLFDN_00808	0.0	miaB	2.8.4.3	-	H	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HLNKLFDN_00809	4.14e-173	ywaC	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
HLNKLFDN_00810	8.53e-222	-	-	-	EG	-	-	-	EamA-like transporter family
HLNKLFDN_00811	4.11e-170	-	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HLNKLFDN_00812	3.44e-155	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
HLNKLFDN_00813	7.35e-309	-	-	-	T	-	-	-	Histidine kinase
HLNKLFDN_00814	8.7e-166	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HLNKLFDN_00815	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
HLNKLFDN_00816	3.27e-150	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HLNKLFDN_00817	1.05e-310	-	-	-	T	-	-	-	Histidine kinase
HLNKLFDN_00818	6.99e-242	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HLNKLFDN_00819	6.01e-287	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HLNKLFDN_00820	2.39e-293	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HLNKLFDN_00821	9.95e-270	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HLNKLFDN_00822	2.23e-150	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Bacterial transferase hexapeptide repeat protein
HLNKLFDN_00823	0.0	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HLNKLFDN_00824	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HLNKLFDN_00825	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HLNKLFDN_00826	2.14e-98	-	-	-	-	-	-	-	-
HLNKLFDN_00827	5.13e-305	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HLNKLFDN_00828	2.11e-169	-	-	-	S	-	-	-	Protein of unknown function (DUF3159)
HLNKLFDN_00829	2.89e-191	-	-	-	S	-	-	-	Protein of unknown function (DUF3710)
HLNKLFDN_00830	1.87e-216	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
HLNKLFDN_00831	0.0	-	-	-	EP	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HLNKLFDN_00832	1.66e-219	dppC	-	-	EP	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
HLNKLFDN_00833	5.78e-197	dppB	-	-	EP	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_00834	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HLNKLFDN_00835	1.04e-215	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HLNKLFDN_00837	2.28e-35	-	-	-	-	-	-	-	-
HLNKLFDN_00838	1.74e-249	tyrA	1.3.1.12	-	E	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
HLNKLFDN_00839	1.86e-243	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
HLNKLFDN_00840	1.67e-134	-	-	-	-	-	-	-	-
HLNKLFDN_00841	0.0	typA	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
HLNKLFDN_00842	0.0	nanT	-	-	U	ko:K03290,ko:K08178,ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
HLNKLFDN_00843	6.41e-193	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX hydrolase
HLNKLFDN_00844	8.39e-196	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
HLNKLFDN_00845	8.61e-224	xerD	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	recombinase XerD
HLNKLFDN_00846	7.76e-81	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HLNKLFDN_00847	3.31e-35	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
HLNKLFDN_00848	1.86e-139	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HLNKLFDN_00849	9.79e-144	-	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamin pyrophosphokinase, vitamin B1 binding domain
HLNKLFDN_00850	4.82e-254	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HLNKLFDN_00851	8.17e-114	ybaK	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HLNKLFDN_00852	1.33e-219	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HLNKLFDN_00853	6.17e-237	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HLNKLFDN_00854	4.37e-50	-	-	-	-	-	-	-	-
HLNKLFDN_00855	7.83e-127	sigH	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HLNKLFDN_00856	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HLNKLFDN_00857	4.04e-241	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
HLNKLFDN_00858	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
HLNKLFDN_00859	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
HLNKLFDN_00860	1.03e-123	-	-	-	F	-	-	-	NUDIX domain
HLNKLFDN_00861	0.0	-	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HLNKLFDN_00862	1.48e-254	dppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_00863	1.15e-242	dppB	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_00864	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HLNKLFDN_00865	7.42e-276	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HLNKLFDN_00866	8.19e-213	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HLNKLFDN_00867	1.13e-275	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
HLNKLFDN_00869	7.06e-315	-	-	-	G	-	-	-	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
HLNKLFDN_00870	6.85e-182	ftsQ	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
HLNKLFDN_00871	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HLNKLFDN_00872	1.05e-273	murG	2.4.1.227, 6.3.2.8	GT28	M	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HLNKLFDN_00873	4.97e-259	ftsW	2.4.1.227	GT28	D	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	Belongs to the SEDS family
HLNKLFDN_00874	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HLNKLFDN_00875	1.95e-251	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HLNKLFDN_00876	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HLNKLFDN_00877	3.4e-197	-	-	-	M	-	-	-	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HLNKLFDN_00878	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding protein, transpeptidase domain protein
HLNKLFDN_00879	7.27e-82	-	-	-	D	-	-	-	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HLNKLFDN_00880	2.34e-241	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HLNKLFDN_00881	9.51e-119	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HLNKLFDN_00882	0.0	-	-	-	L	-	-	-	DNA helicase
HLNKLFDN_00883	6.86e-276	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HLNKLFDN_00884	2.49e-110	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HLNKLFDN_00885	1.42e-68	-	-	-	M	-	-	-	Lysin motif
HLNKLFDN_00886	6.88e-170	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HLNKLFDN_00887	3.34e-192	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HLNKLFDN_00888	3.25e-225	ldh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HLNKLFDN_00889	0.0	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HLNKLFDN_00890	5.64e-146	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
HLNKLFDN_00891	0.0	hrpA	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Helicase associated domain (HA2) Add an annotation
HLNKLFDN_00892	3.48e-246	-	-	-	-	-	-	-	-
HLNKLFDN_00893	3.65e-199	-	-	-	V	-	-	-	N-Acetylmuramoyl-L-alanine amidase
HLNKLFDN_00894	1.12e-127	-	-	-	-	-	-	-	-
HLNKLFDN_00895	5.66e-72	-	-	-	T	-	-	-	helix_turn_helix, Lux Regulon
HLNKLFDN_00897	6.15e-153	-	-	-	V	ko:K02003,ko:K09810	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HLNKLFDN_00898	2.12e-278	-	-	-	EGP	ko:K18567,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
HLNKLFDN_00899	6.77e-185	-	-	-	M	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HLNKLFDN_00900	6.42e-309	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
HLNKLFDN_00901	0.0	glnA2	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HLNKLFDN_00902	2.38e-167	hisA	5.3.1.16, 5.3.1.24	-	E	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
HLNKLFDN_00903	1.77e-156	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HLNKLFDN_00904	9.4e-163	-	-	-	-	-	-	-	-
HLNKLFDN_00905	4.56e-142	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
HLNKLFDN_00906	1.36e-287	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HLNKLFDN_00907	0.0	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HLNKLFDN_00908	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
HLNKLFDN_00909	3.52e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HLNKLFDN_00910	5.61e-121	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HLNKLFDN_00911	5.08e-64	-	-	-	V	-	-	-	DivIVA protein
HLNKLFDN_00912	9.14e-55	-	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HLNKLFDN_00913	5.84e-105	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HLNKLFDN_00914	4.66e-279	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HLNKLFDN_00915	1.31e-310	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HLNKLFDN_00916	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
HLNKLFDN_00917	1.35e-136	-	-	-	S	ko:K02664	-	ko00000,ko02035,ko02044	Pilus assembly protein, PilO
HLNKLFDN_00918	1.62e-210	-	-	-	NU	-	-	-	PFAM Fimbrial assembly family protein
HLNKLFDN_00919	2.5e-82	pilM	-	-	NU	ko:K02662	-	ko00000,ko02035,ko02044	Type IV pilus assembly protein PilM;
HLNKLFDN_00920	0.0	pilB	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
HLNKLFDN_00921	0.0	pilT	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
HLNKLFDN_00922	4.66e-198	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HLNKLFDN_00923	2.73e-171	thiE	2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17	-	H	ko:K03147,ko:K14153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HLNKLFDN_00924	4.31e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HLNKLFDN_00925	3.37e-79	-	-	-	S	-	-	-	Thiamine-binding protein
HLNKLFDN_00926	1.86e-246	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HLNKLFDN_00927	1.54e-307	lacY	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
HLNKLFDN_00928	0.0	fosC	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HLNKLFDN_00929	1.43e-189	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_00930	1.43e-261	-	-	-	P	-	-	-	NMT1/THI5 like
HLNKLFDN_00931	1.05e-290	-	-	-	F	-	-	-	nucleoside hydrolase
HLNKLFDN_00932	8.46e-197	uppS	2.5.1.31, 2.5.1.86, 2.5.1.88	-	H	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HLNKLFDN_00933	4.14e-173	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HLNKLFDN_00934	0.0	-	-	-	I	-	-	-	acetylesterase activity
HLNKLFDN_00935	1.93e-286	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HLNKLFDN_00936	2.8e-276	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HLNKLFDN_00937	0.0	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
HLNKLFDN_00939	3.68e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3052)
HLNKLFDN_00940	3.48e-197	sdrC	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HLNKLFDN_00941	0.0	-	-	-	S	-	-	-	Zincin-like metallopeptidase
HLNKLFDN_00942	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HLNKLFDN_00943	0.0	mphA	-	-	S	-	-	-	Aminoglycoside phosphotransferase
HLNKLFDN_00944	4.61e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF3107)
HLNKLFDN_00945	8.5e-213	PPA1328	3.1.3.97, 3.1.4.57	-	S	ko:K07053,ko:K20859	ko00440,map00440	ko00000,ko00001,ko01000	DNA polymerase alpha chain like domain
HLNKLFDN_00946	5.01e-150	-	-	-	S	-	-	-	Vitamin K epoxide reductase
HLNKLFDN_00947	4.23e-215	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
HLNKLFDN_00948	6.94e-183	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HLNKLFDN_00949	1.14e-24	-	-	-	S	ko:K07001	-	ko00000	lipid catabolic process
HLNKLFDN_00950	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HLNKLFDN_00951	1.95e-226	iaaA	3.4.19.5	-	E	ko:K13051	-	ko00000,ko01000,ko01002	Asparaginase
HLNKLFDN_00952	3.79e-203	-	-	-	S	-	-	-	Patatin-like phospholipase
HLNKLFDN_00953	5.08e-238	-	-	-	K	-	-	-	LysR substrate binding domain protein
HLNKLFDN_00954	1.4e-308	-	4.4.1.8	-	E	ko:K00842,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
HLNKLFDN_00955	6.31e-156	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
HLNKLFDN_00956	1.36e-108	-	-	-	-	-	-	-	-
HLNKLFDN_00957	2.5e-15	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HLNKLFDN_00958	0.0	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HLNKLFDN_00959	2.28e-117	-	-	-	-	ko:K19133	-	ko00000,ko02048	-
HLNKLFDN_00960	3.83e-256	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase Cas3
HLNKLFDN_00961	5.48e-125	-	-	-	-	ko:K19132	-	ko00000,ko02048	-
HLNKLFDN_00962	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HLNKLFDN_00963	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HLNKLFDN_00964	7.21e-237	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HLNKLFDN_00965	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HLNKLFDN_00966	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HLNKLFDN_00967	1.65e-134	-	-	-	K	-	-	-	MarR family
HLNKLFDN_00968	0.0	bglB	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
HLNKLFDN_00969	1.66e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLNKLFDN_00970	5.59e-245	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HLNKLFDN_00971	4.24e-232	-	-	-	G	-	-	-	Transporter major facilitator family protein
HLNKLFDN_00972	0.0	-	3.2.1.40	-	E	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase C-terminal domain
HLNKLFDN_00973	4.89e-273	-	-	-	U	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
HLNKLFDN_00974	1.45e-145	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein domain
HLNKLFDN_00975	2.87e-17	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HLNKLFDN_00976	5.7e-279	-	-	-	U	ko:K08168,ko:K18926	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
HLNKLFDN_00977	0.0	bgl2	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
HLNKLFDN_00978	6.15e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLNKLFDN_00979	1.73e-307	-	3.2.1.4, 3.2.1.58	GH5,GH9	G	ko:K01179,ko:K01210	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HLNKLFDN_00980	0.0	-	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 43
HLNKLFDN_00981	1.59e-312	-	3.2.1.4, 3.2.1.58	GH5,GH9	G	ko:K01179,ko:K01210	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HLNKLFDN_00983	0.0	-	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
HLNKLFDN_00984	1.06e-284	-	-	-	G	-	-	-	MFS/sugar transport protein
HLNKLFDN_00985	1.28e-172	-	-	-	K	-	-	-	transcriptional regulator
HLNKLFDN_00986	0.0	-	3.2.1.45	GH30	G	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 TIM-barrel domain
HLNKLFDN_00987	6.02e-305	-	-	-	G	-	-	-	Transporter major facilitator family protein
HLNKLFDN_00988	3.55e-139	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLNKLFDN_00989	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Beta-galactosidase trimerisation domain
HLNKLFDN_00990	5.5e-148	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLNKLFDN_00991	0.0	egtA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Glutamate-cysteine ligase family 2(GCS2)
HLNKLFDN_00992	0.0	hgdC	-	-	I	-	-	-	CoA enzyme activase uncharacterised domain (DUF2229)
HLNKLFDN_00993	5.91e-199	-	-	-	I	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
HLNKLFDN_00994	3.18e-179	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HLNKLFDN_00995	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
HLNKLFDN_00996	3.66e-312	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLNKLFDN_00997	8.4e-56	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLNKLFDN_00999	3.24e-250	-	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
HLNKLFDN_01001	9.87e-47	VY92_01845	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HLNKLFDN_01003	6.97e-129	tmp1	-	-	S	-	-	-	Domain of unknown function (DUF4391)
HLNKLFDN_01004	1.11e-214	ppx1	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
HLNKLFDN_01005	1.75e-295	aspB	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
HLNKLFDN_01006	2.71e-92	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HLNKLFDN_01007	1.44e-191	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HLNKLFDN_01008	0.0	-	3.6.4.12	-	L	ko:K03658	-	ko00000,ko01000,ko03400	Psort location Cytoplasmic, score 8.87
HLNKLFDN_01009	3.01e-30	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HLNKLFDN_01010	1.63e-283	-	-	-	L	ko:K07496	-	ko00000	Psort location Cytoplasmic, score 8.87
HLNKLFDN_01011	2.03e-92	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HLNKLFDN_01012	0.0	-	-	-	KL	-	-	-	Domain of unknown function (DUF3427)
HLNKLFDN_01013	2.94e-99	-	-	-	-	-	-	-	-
HLNKLFDN_01014	8.64e-97	-	-	-	S	-	-	-	Bacterial PH domain
HLNKLFDN_01015	7.08e-315	-	-	-	S	-	-	-	zinc finger
HLNKLFDN_01020	1.5e-213	-	-	-	M	-	-	-	Bacteriophage peptidoglycan hydrolase
HLNKLFDN_01021	1.4e-154	-	-	-	-	-	-	-	-
HLNKLFDN_01022	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	long-chain-fatty acid CoA ligase
HLNKLFDN_01023	1.22e-107	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HLNKLFDN_01024	7.33e-183	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HLNKLFDN_01025	6.23e-184	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HLNKLFDN_01027	2.04e-172	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HLNKLFDN_01028	6.26e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HLNKLFDN_01029	5.62e-228	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
HLNKLFDN_01030	4.56e-287	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HLNKLFDN_01031	1.61e-177	hisF	4.1.3.27	-	E	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HLNKLFDN_01032	9.19e-95	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HLNKLFDN_01033	0.0	trpE	4.1.3.27	-	E	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HLNKLFDN_01034	0.0	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HLNKLFDN_01035	3.73e-206	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HLNKLFDN_01036	2.39e-231	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HLNKLFDN_01037	2.25e-137	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3-epimerase
HLNKLFDN_01038	1.2e-54	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-ATP pyrophosphohydrolase
HLNKLFDN_01039	2.06e-198	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
HLNKLFDN_01040	1.2e-133	pgsA2	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HLNKLFDN_01041	4.4e-220	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
HLNKLFDN_01042	2.68e-64	sbp	-	-	S	-	-	-	Protein of unknown function (DUF1290)
HLNKLFDN_01043	2.17e-180	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
HLNKLFDN_01044	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HLNKLFDN_01045	2e-135	pgsA1	2.7.8.11, 2.7.8.5	-	I	ko:K00995,ko:K00999	ko00562,ko00564,ko01100,ko04070,map00562,map00564,map01100,map04070	ko00000,ko00001,ko01000	CDP-alcohol phosphatidyltransferase
HLNKLFDN_01046	2.38e-172	yebC	-	-	K	-	-	-	transcriptional regulatory protein
HLNKLFDN_01047	2.73e-129	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HLNKLFDN_01048	1.34e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HLNKLFDN_01049	2.78e-255	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HLNKLFDN_01050	1.89e-81	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
HLNKLFDN_01051	5.27e-130	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HLNKLFDN_01052	5.48e-281	sucC	6.2.1.5	-	F	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HLNKLFDN_01053	1.1e-205	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HLNKLFDN_01054	0.0	-	-	-	-	-	-	-	-
HLNKLFDN_01055	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HLNKLFDN_01056	1.69e-48	-	-	-	-	-	-	-	-
HLNKLFDN_01057	1.97e-206	-	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HLNKLFDN_01058	9.79e-184	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HLNKLFDN_01059	0.0	der	-	-	F	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HLNKLFDN_01060	8.64e-92	-	-	-	-	-	-	-	-
HLNKLFDN_01062	0.0	ugp	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HLNKLFDN_01063	0.0	-	-	-	K	-	-	-	WYL domain
HLNKLFDN_01064	2.4e-73	-	-	-	-	-	-	-	-
HLNKLFDN_01065	0.0	helY	-	-	L	ko:K03727	-	ko00000,ko01000	DEAD DEAH box helicase
HLNKLFDN_01066	2.24e-81	rbpA	-	-	K	-	-	-	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
HLNKLFDN_01067	5.93e-181	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
HLNKLFDN_01068	1.54e-80	-	-	-	-	-	-	-	-
HLNKLFDN_01069	2.15e-144	merR2	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HLNKLFDN_01070	9.05e-98	garA	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
HLNKLFDN_01071	3.74e-48	-	-	-	-	-	-	-	-
HLNKLFDN_01079	2.29e-199	-	-	-	S	-	-	-	PAC2 family
HLNKLFDN_01080	1.44e-199	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HLNKLFDN_01081	1.58e-201	-	-	-	G	-	-	-	Fructosamine kinase
HLNKLFDN_01082	6.98e-265	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HLNKLFDN_01083	7.99e-251	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HLNKLFDN_01084	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
HLNKLFDN_01085	4.69e-260	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HLNKLFDN_01086	3.88e-55	nadR	-	-	H	-	-	-	ATPase kinase involved in NAD metabolism
HLNKLFDN_01087	2.36e-138	-	-	-	H	ko:K03811	-	ko00000,ko02000	Nicotinamide mononucleotide transporter
HLNKLFDN_01089	0.0	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase, class I II
HLNKLFDN_01090	1.58e-208	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HLNKLFDN_01091	4.98e-44	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
HLNKLFDN_01092	5.69e-191	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HLNKLFDN_01093	3.72e-281	pgk	2.7.2.3, 5.3.1.1	-	F	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
HLNKLFDN_01094	2.1e-219	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HLNKLFDN_01095	4.41e-218	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HLNKLFDN_01096	9.81e-233	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate dehydrogenase substrate binding domain
HLNKLFDN_01097	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HLNKLFDN_01098	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HLNKLFDN_01099	2.91e-280	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HLNKLFDN_01100	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HLNKLFDN_01101	3.25e-179	-	-	-	S	-	-	-	Domain of unknown function (DUF4194)
HLNKLFDN_01102	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HLNKLFDN_01103	1.13e-18	-	-	-	-	-	-	-	-
HLNKLFDN_01105	1.84e-87	ogt	2.1.1.63	-	L	ko:K00567,ko:K07443	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HLNKLFDN_01106	1.85e-142	pncA	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Isochorismatase family
HLNKLFDN_01107	0.0	ybiT	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HLNKLFDN_01109	3.84e-221	-	-	-	S	-	-	-	IMP dehydrogenase activity
HLNKLFDN_01110	0.0	-	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HLNKLFDN_01111	8.69e-183	mazG	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	Psort location Cytoplasmic, score 8.87
HLNKLFDN_01112	1.48e-196	-	-	-	-	-	-	-	-
HLNKLFDN_01113	1.34e-163	-	-	-	-	ko:K03646	-	ko00000,ko02000	-
HLNKLFDN_01116	5.23e-233	-	-	-	P	-	-	-	Cation efflux family
HLNKLFDN_01117	5.77e-100	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HLNKLFDN_01118	7.46e-282	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
HLNKLFDN_01119	1.31e-185	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HLNKLFDN_01120	5.2e-252	adh	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
HLNKLFDN_01121	2.39e-93	-	-	-	K	-	-	-	MerR family regulatory protein
HLNKLFDN_01122	3.51e-154	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HLNKLFDN_01123	4.34e-237	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HLNKLFDN_01124	5.47e-152	yoaP	-	-	E	-	-	-	YoaP-like
HLNKLFDN_01126	5.38e-249	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HLNKLFDN_01127	9.67e-110	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	FR47-like protein
HLNKLFDN_01128	6.89e-190	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Glycoprotease family
HLNKLFDN_01129	7.17e-119	tsaE	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
HLNKLFDN_01130	2.13e-228	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HLNKLFDN_01131	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
HLNKLFDN_01132	1.52e-135	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
HLNKLFDN_01133	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HLNKLFDN_01134	1.84e-180	-	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HLNKLFDN_01135	1.48e-219	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HLNKLFDN_01136	1.72e-210	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
HLNKLFDN_01139	0.0	-	-	-	M	-	-	-	domain protein
HLNKLFDN_01140	4.75e-92	pdxH	-	-	S	ko:K07006	-	ko00000	Pfam:Pyridox_oxidase
HLNKLFDN_01141	1.17e-289	-	-	-	K	-	-	-	Fic/DOC family
HLNKLFDN_01143	1.14e-158	-	-	-	-	-	-	-	-
HLNKLFDN_01144	7.33e-183	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
HLNKLFDN_01145	3.94e-88	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HLNKLFDN_01146	2.71e-316	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HLNKLFDN_01147	1.7e-91	-	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HLNKLFDN_01148	5.78e-139	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease, DNA polymerase III, epsilon subunit family
HLNKLFDN_01149	1.07e-265	guaB3	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase family protein
HLNKLFDN_01150	1.58e-305	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
HLNKLFDN_01151	0.0	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
HLNKLFDN_01152	0.0	fadD1	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HLNKLFDN_01153	8.01e-124	-	-	-	M	-	-	-	Peptidase family M23
HLNKLFDN_01154	1.8e-83	-	-	-	-	-	-	-	-
HLNKLFDN_01157	5.36e-161	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HLNKLFDN_01158	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HLNKLFDN_01159	3.2e-157	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HLNKLFDN_01160	4.13e-180	-	-	-	S	-	-	-	SdpI/YhfL protein family
HLNKLFDN_01161	6.64e-67	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HLNKLFDN_01162	3.66e-157	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HLNKLFDN_01163	1.09e-277	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
HLNKLFDN_01164	4.36e-89	arsC	1.20.4.1, 2.8.4.2	-	T	ko:K03741,ko:K18701	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HLNKLFDN_01165	9.59e-141	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HLNKLFDN_01166	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HLNKLFDN_01167	2.46e-209	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HLNKLFDN_01168	9.36e-160	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HLNKLFDN_01169	8.22e-230	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HLNKLFDN_01170	5.08e-198	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
HLNKLFDN_01171	1.44e-228	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
HLNKLFDN_01172	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HLNKLFDN_01173	1.06e-96	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
HLNKLFDN_01174	8.48e-241	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HLNKLFDN_01175	0.0	glnE	2.7.7.42, 2.7.7.89	-	H	ko:K00982	-	ko00000,ko01000	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
HLNKLFDN_01176	1.42e-202	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
HLNKLFDN_01177	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HLNKLFDN_01178	1.67e-128	sixA	-	-	T	ko:K08296	-	ko00000,ko01000	Phosphoglycerate mutase family
HLNKLFDN_01179	2.79e-253	trmI	2.1.1.219, 2.1.1.220	-	J	ko:K07442	-	ko00000,ko01000,ko03016	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HLNKLFDN_01180	2.73e-203	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HLNKLFDN_01181	9.94e-317	glgA	2.4.1.342	GT4	G	ko:K16148	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Starch synthase catalytic domain
HLNKLFDN_01182	3.85e-98	-	-	-	-	-	-	-	-
HLNKLFDN_01183	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HLNKLFDN_01184	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase NADPH large subunit
HLNKLFDN_01185	2.6e-296	-	-	-	F	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HLNKLFDN_01186	3.03e-277	-	-	-	H	-	-	-	long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase
HLNKLFDN_01187	0.0	-	-	-	C	-	-	-	Acyl-CoA reductase (LuxC)
HLNKLFDN_01188	9.78e-188	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HLNKLFDN_01189	3.02e-296	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HLNKLFDN_01190	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HLNKLFDN_01191	7.89e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HLNKLFDN_01192	8.65e-174	-	-	-	S	-	-	-	UPF0126 domain
HLNKLFDN_01193	8.14e-290	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Amino-transferase class IV
HLNKLFDN_01195	2.46e-65	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HLNKLFDN_01196	1e-76	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLNKLFDN_01197	6.46e-116	-	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLNKLFDN_01198	3.04e-126	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HLNKLFDN_01199	1.08e-249	-	-	-	S	ko:K06889	-	ko00000	alpha beta
HLNKLFDN_01200	9.97e-36	yhjX	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major facilitator Superfamily
HLNKLFDN_01201	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HLNKLFDN_01202	2.96e-242	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLNKLFDN_01204	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLNKLFDN_01205	2.2e-95	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
HLNKLFDN_01206	3.96e-53	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HLNKLFDN_01207	5.26e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLNKLFDN_01208	5.92e-282	-	-	-	G	-	-	-	Transmembrane secretion effector
HLNKLFDN_01210	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HLNKLFDN_01211	0.0	pntB	1.6.1.2	-	C	ko:K00325	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HLNKLFDN_01212	1.02e-57	pntAB	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	4TM region of pyridine nucleotide transhydrogenase, mitoch
HLNKLFDN_01213	3.43e-260	pntA	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	NAD(P) transhydrogenase subunit alpha part 1 K00324
HLNKLFDN_01214	0.0	fadD2	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HLNKLFDN_01215	2.58e-228	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HLNKLFDN_01216	0.0	corC	-	-	S	-	-	-	CBS domain
HLNKLFDN_01217	1.14e-133	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HLNKLFDN_01218	8.19e-267	phoH	-	-	T	ko:K06217	-	ko00000	PhoH-like protein
HLNKLFDN_01219	8.96e-75	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
HLNKLFDN_01220	5.66e-187	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HLNKLFDN_01222	5e-207	spoU2	-	-	J	-	-	-	SpoU rRNA Methylase family
HLNKLFDN_01223	5.57e-310	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HLNKLFDN_01224	1.31e-139	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HLNKLFDN_01225	6.78e-128	iscU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HLNKLFDN_01226	7.25e-302	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HLNKLFDN_01227	1.14e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HLNKLFDN_01228	7.47e-300	sufD	-	-	O	ko:K09015	-	ko00000	FeS assembly protein SufD
HLNKLFDN_01229	0.0	sufB	-	-	O	ko:K09014	-	ko00000	FeS assembly protein SufB
HLNKLFDN_01230	0.0	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HLNKLFDN_01231	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HLNKLFDN_01232	0.0	-	3.2.1.1, 3.2.1.41	CBM48,GH13	M	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	Aamy_C
HLNKLFDN_01233	3.9e-105	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
HLNKLFDN_01234	0.0	aroB	2.7.1.71, 4.2.3.4	-	H	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HLNKLFDN_01235	1.64e-282	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HLNKLFDN_01236	2.43e-84	-	3.4.23.43	-	S	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
HLNKLFDN_01237	2.36e-253	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HLNKLFDN_01238	1.06e-106	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HLNKLFDN_01239	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HLNKLFDN_01240	6.83e-50	-	-	-	-	-	-	-	-
HLNKLFDN_01241	8.09e-79	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
HLNKLFDN_01242	9.46e-167	-	5.4.2.12	-	G	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
HLNKLFDN_01243	1.33e-72	-	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HLNKLFDN_01244	3.17e-142	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HLNKLFDN_01245	3.67e-192	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HLNKLFDN_01246	8.69e-277	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HLNKLFDN_01247	3.23e-80	-	-	-	S	-	-	-	Domain of unknown function (DUF4418)
HLNKLFDN_01248	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HLNKLFDN_01249	2.66e-138	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HLNKLFDN_01250	1.23e-311	pbuX	-	-	F	ko:K03458	-	ko00000	Permease family
HLNKLFDN_01251	0.0	yrhL	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HLNKLFDN_01252	8.03e-296	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HLNKLFDN_01253	0.0	pta	2.3.1.8	-	C	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphate acetyltransferase
HLNKLFDN_01254	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
HLNKLFDN_01255	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HLNKLFDN_01256	3.28e-100	-	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HLNKLFDN_01257	1.86e-92	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HLNKLFDN_01258	0.0	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HLNKLFDN_01260	1.41e-82	-	-	-	S	-	-	-	MvaI/BcnI restriction endonuclease family
HLNKLFDN_01261	2.62e-148	dcm	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	DNA (cytosine-5-)-methyltransferase activity
HLNKLFDN_01263	6.52e-67	-	-	-	-	-	-	-	-
HLNKLFDN_01264	4.25e-45	-	-	-	-	-	-	-	-
HLNKLFDN_01268	3.32e-92	XK26_04895	-	-	-	-	-	-	-
HLNKLFDN_01269	2.77e-10	-	-	-	L	-	-	-	HNH endonuclease
HLNKLFDN_01272	3.76e-268	-	-	-	-	-	-	-	-
HLNKLFDN_01273	0.0	glgX	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
HLNKLFDN_01274	9.82e-156	-	-	-	L	-	-	-	NUDIX domain
HLNKLFDN_01275	1.48e-216	-	-	-	L	-	-	-	NIF3 (NGG1p interacting factor 3)
HLNKLFDN_01276	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HLNKLFDN_01277	8.64e-156	pdtaR	-	-	T	ko:K22010	-	ko00000,ko00002,ko02022	Response regulator receiver domain protein
HLNKLFDN_01278	4.26e-208	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
HLNKLFDN_01281	1.1e-16	-	-	-	-	-	-	-	-
HLNKLFDN_01282	7.94e-78	yccF	-	-	S	-	-	-	Inner membrane component domain
HLNKLFDN_01283	8.2e-152	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLNKLFDN_01284	2.32e-269	-	-	-	G	-	-	-	Transmembrane secretion effector
HLNKLFDN_01285	1.44e-22	-	-	-	K	ko:K21498	-	ko00000,ko02048	addiction module antidote protein HigA
HLNKLFDN_01286	4.93e-306	-	-	-	S	-	-	-	HipA-like C-terminal domain
HLNKLFDN_01287	3.03e-257	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HLNKLFDN_01288	4.74e-175	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HLNKLFDN_01289	0.0	pip	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	alpha/beta hydrolase fold
HLNKLFDN_01290	0.0	-	-	-	T	-	-	-	Histidine kinase
HLNKLFDN_01291	3.36e-166	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HLNKLFDN_01292	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HLNKLFDN_01293	1.28e-182	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLNKLFDN_01294	2.42e-245	asnC	-	-	K	ko:K03718	-	ko00000,ko03000	helix_turn_helix ASNC type
HLNKLFDN_01295	4.49e-192	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HLNKLFDN_01296	0.0	ykoD	-	-	P	ko:K16784,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HLNKLFDN_01297	1.88e-124	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HLNKLFDN_01298	0.0	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Aminotransferase class-V
HLNKLFDN_01299	1.06e-211	pdxY	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HLNKLFDN_01300	1.85e-108	yraN	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
HLNKLFDN_01301	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
HLNKLFDN_01302	0.0	dprA	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
HLNKLFDN_01303	0.0	sdhA	1.3.5.1, 1.3.5.4, 1.4.3.16	-	C	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Succinate dehydrogenase flavoprotein subunit
HLNKLFDN_01304	4.82e-226	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
HLNKLFDN_01305	1.01e-150	safC	-	-	S	-	-	-	O-methyltransferase
HLNKLFDN_01306	2.92e-315	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HLNKLFDN_01309	6.72e-307	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HLNKLFDN_01310	9.35e-161	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HLNKLFDN_01311	1.25e-147	clpP1	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HLNKLFDN_01312	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HLNKLFDN_01313	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HLNKLFDN_01314	7.19e-219	-	-	-	U	ko:K02057,ko:K10440,ko:K17209	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HLNKLFDN_01315	2.87e-231	ytfT	-	-	U	ko:K02057,ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HLNKLFDN_01316	0.0	-	3.6.3.17	-	G	ko:K02056,ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HLNKLFDN_01317	5.1e-218	-	-	-	G	ko:K02058,ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
HLNKLFDN_01318	0.0	lpqB	-	-	S	-	-	-	Lipoprotein LpqB beta-propeller domain
HLNKLFDN_01319	0.0	mtrB	2.7.13.3	-	T	ko:K07636,ko:K07654	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HLNKLFDN_01320	6.21e-171	mtrA	-	-	KT	ko:K07670	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HLNKLFDN_01321	0.0	rarA	-	-	L	ko:K07478	-	ko00000	Recombination factor protein RarA
HLNKLFDN_01322	0.0	-	-	-	L	-	-	-	DEAD DEAH box helicase
HLNKLFDN_01323	4.93e-244	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HLNKLFDN_01324	3.03e-258	gluD	-	-	E	ko:K10007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_01325	1.04e-144	gluC	-	-	E	ko:K10006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_01326	1.69e-195	gluB	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HLNKLFDN_01327	3.16e-176	gluA	-	-	E	ko:K10008	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding protein of ABC transporter for glutamate K02028
HLNKLFDN_01328	5.63e-177	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HLNKLFDN_01329	0.0	glnP	-	-	E	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_01330	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HLNKLFDN_01331	0.0	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
HLNKLFDN_01332	6.87e-300	-	-	-	S	-	-	-	Domain of Unknown Function (DUF349)
HLNKLFDN_01333	1.92e-177	-	3.5.2.10	-	S	ko:K01470	ko00330,map00330	ko00000,ko00001,ko01000	Creatinine amidohydrolase
HLNKLFDN_01334	2.1e-313	proP	-	-	EGP	ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
HLNKLFDN_01335	0.0	-	-	-	QT	-	-	-	Purine catabolism regulatory protein-like family
HLNKLFDN_01336	0.0	codA	3.5.4.1, 3.5.4.21	-	F	ko:K01485,ko:K03365	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
HLNKLFDN_01337	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
HLNKLFDN_01338	6.45e-241	uspA	-	-	T	-	-	-	Belongs to the universal stress protein A family
HLNKLFDN_01339	1.23e-243	-	-	-	S	-	-	-	Protein of unknown function (DUF3027)
HLNKLFDN_01340	6.1e-88	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HLNKLFDN_01341	0.0	phoR	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HLNKLFDN_01342	3.53e-170	phoP	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulator receiver domain protein
HLNKLFDN_01343	2.4e-166	-	-	-	-	-	-	-	-
HLNKLFDN_01344	1.74e-38	-	-	-	S	-	-	-	Proteins of 100 residues with WXG
HLNKLFDN_01345	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HLNKLFDN_01346	1.2e-117	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
HLNKLFDN_01347	9.46e-176	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HLNKLFDN_01348	1.31e-233	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HLNKLFDN_01349	1.22e-223	-	-	-	S	-	-	-	Protein of unknown function DUF58
HLNKLFDN_01350	1.57e-119	-	-	-	-	-	-	-	-
HLNKLFDN_01351	1.78e-242	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
HLNKLFDN_01352	7.17e-234	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
HLNKLFDN_01353	9.53e-102	-	-	-	-	-	-	-	-
HLNKLFDN_01354	0.0	-	-	-	S	-	-	-	PGAP1-like protein
HLNKLFDN_01355	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminal
HLNKLFDN_01356	0.0	-	-	-	S	-	-	-	Lysylphosphatidylglycerol synthase TM region
HLNKLFDN_01357	4.7e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
HLNKLFDN_01358	1.11e-77	-	-	-	-	-	-	-	-
HLNKLFDN_01359	7.66e-181	-	-	-	C	-	-	-	FMN binding
HLNKLFDN_01360	0.0	pafA	6.3.1.19	-	O	ko:K13571	-	ko00000,ko00002,ko01000,ko03051	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HLNKLFDN_01361	5.14e-34	pup	-	-	S	ko:K13570	-	ko00000,ko04121	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
HLNKLFDN_01362	8.18e-206	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
HLNKLFDN_01363	0.0	dop	3.5.1.119	-	S	ko:K20814	-	ko00000,ko01000,ko03051	Pup-ligase protein
HLNKLFDN_01364	0.0	arc	-	-	O	ko:K13527	ko03050,map03050	ko00000,ko00001,ko00002,ko03051	AAA ATPase forming ring-shaped complexes
HLNKLFDN_01365	1.29e-158	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
HLNKLFDN_01366	3.54e-229	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HLNKLFDN_01367	3.02e-173	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HLNKLFDN_01368	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HLNKLFDN_01369	9.67e-284	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HLNKLFDN_01370	5.45e-61	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HLNKLFDN_01371	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
HLNKLFDN_01373	3.1e-138	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HLNKLFDN_01374	1.42e-218	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HLNKLFDN_01375	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HLNKLFDN_01376	5.95e-305	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HLNKLFDN_01377	1.21e-98	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HLNKLFDN_01378	2.2e-134	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HLNKLFDN_01379	2.12e-295	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HLNKLFDN_01380	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HLNKLFDN_01381	9.4e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HLNKLFDN_01382	5.77e-81	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HLNKLFDN_01383	1.51e-240	-	-	-	S	ko:K03453	-	ko00000	SBF-like CPA transporter family (DUF4137)
HLNKLFDN_01385	5.2e-253	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
HLNKLFDN_01386	2.64e-289	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
HLNKLFDN_01387	4.94e-288	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HLNKLFDN_01388	1.97e-175	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HLNKLFDN_01389	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
HLNKLFDN_01390	1.79e-46	-	-	-	-	-	-	-	-
HLNKLFDN_01391	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	DNA-damage repair protein (DNA polymerase IV) K00961
HLNKLFDN_01392	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HLNKLFDN_01393	1.07e-242	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HLNKLFDN_01394	8.42e-299	purD	6.3.3.1, 6.3.4.13	-	F	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HLNKLFDN_01395	5.47e-314	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HLNKLFDN_01396	8.1e-236	rihB	3.2.2.1, 3.2.2.8	-	F	ko:K01239,ko:K01250,ko:K10213	ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HLNKLFDN_01397	4.27e-273	-	-	-	C	ko:K19954	-	ko00000,ko01000	Iron-containing alcohol dehydrogenase
HLNKLFDN_01398	1.06e-165	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	N-(5'phosphoribosyl)anthranilate (PRA) isomerase
HLNKLFDN_01399	1.85e-241	yeiI	2.7.1.15, 2.7.1.45, 2.7.1.83	-	G	ko:K00852,ko:K00874,ko:K16328	ko00030,ko00240,ko01100,ko01120,ko01200,map00030,map00240,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
HLNKLFDN_01400	1.9e-258	-	2.7.1.83	-	G	ko:K16328	ko00240,map00240	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HLNKLFDN_01401	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
HLNKLFDN_01402	1.28e-91	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HLNKLFDN_01403	1.11e-285	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HLNKLFDN_01404	2.09e-110	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HLNKLFDN_01405	3.84e-233	yogA	-	-	C	-	-	-	Zinc-binding dehydrogenase
HLNKLFDN_01406	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HLNKLFDN_01407	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HLNKLFDN_01408	3.77e-205	-	-	-	M	-	-	-	Conserved repeat domain
HLNKLFDN_01409	2.8e-172	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HLNKLFDN_01410	7e-99	-	-	-	-	-	-	-	-
HLNKLFDN_01411	2.8e-19	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HLNKLFDN_01412	1.89e-178	hflK	-	-	O	-	-	-	prohibitin homologues
HLNKLFDN_01413	7.85e-59	-	-	-	O	-	-	-	Glutaredoxin
HLNKLFDN_01414	1.67e-98	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HLNKLFDN_01415	5.27e-281	-	2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83	-	E	ko:K00812,ko:K08969,ko:K10206,ko:K14260,ko:K14261	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HLNKLFDN_01416	3.58e-133	-	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 9.99
HLNKLFDN_01417	3.75e-227	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HLNKLFDN_01418	1.68e-197	metQ	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
HLNKLFDN_01419	4.24e-256	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HLNKLFDN_01420	2.05e-203	glnH	-	-	ET	ko:K02030,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HLNKLFDN_01421	2.39e-192	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATP binding protein of ABC transporter for glutamate aspartate K02028
HLNKLFDN_01422	3.03e-157	glnP	-	-	E	ko:K02029,ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_01423	5.59e-141	glnP2	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_01424	3.74e-148	-	-	-	K	-	-	-	acetyltransferase
HLNKLFDN_01428	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
HLNKLFDN_01430	9.29e-225	-	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
HLNKLFDN_01432	1.13e-273	-	-	-	P	-	-	-	Citrate transporter
HLNKLFDN_01433	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HLNKLFDN_01434	0.0	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HLNKLFDN_01435	0.0	aap1	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
HLNKLFDN_01436	4.58e-131	cysE	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HLNKLFDN_01437	1.29e-117	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HLNKLFDN_01438	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HLNKLFDN_01439	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HLNKLFDN_01440	4.68e-280	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HLNKLFDN_01441	2.45e-244	cbs	2.5.1.47, 4.2.1.22	-	E	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HLNKLFDN_01442	1.46e-177	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HLNKLFDN_01443	3.93e-176	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	oligopeptide transport protein of the ABC superfamily, ATP-binding component
HLNKLFDN_01444	5.4e-201	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_01445	8.06e-213	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_01446	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HLNKLFDN_01447	3.26e-306	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HLNKLFDN_01448	8.08e-185	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HLNKLFDN_01449	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HLNKLFDN_01450	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HLNKLFDN_01451	0.0	abfA1	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	arabinose metabolic process
HLNKLFDN_01452	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HLNKLFDN_01453	3.46e-41	yuxJ	-	-	EGP	-	-	-	Major facilitator Superfamily
HLNKLFDN_01454	2.4e-61	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HLNKLFDN_01455	2.95e-117	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HLNKLFDN_01457	1.08e-76	-	-	-	-	-	-	-	-
HLNKLFDN_01458	0.0	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
HLNKLFDN_01459	2.64e-15	-	-	-	-	-	-	-	-
HLNKLFDN_01460	1.59e-105	-	-	-	-	-	-	-	-
HLNKLFDN_01461	0.0	-	-	-	S	ko:K07133	-	ko00000	AAA domain
HLNKLFDN_01462	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HLNKLFDN_01464	6.64e-222	-	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferase family 2
HLNKLFDN_01465	0.0	-	-	-	-	-	-	-	-
HLNKLFDN_01466	8.13e-276	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HLNKLFDN_01467	3.97e-255	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HLNKLFDN_01468	0.0	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HLNKLFDN_01469	1.76e-267	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HLNKLFDN_01470	1.56e-175	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HLNKLFDN_01471	5.29e-230	-	-	-	GM	-	-	-	GDP-mannose 4,6 dehydratase
HLNKLFDN_01472	3.48e-188	tagG	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HLNKLFDN_01473	8.84e-305	-	-	-	GM	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLNKLFDN_01474	0.0	-	-	-	S	-	-	-	Psort location Extracellular, score
HLNKLFDN_01475	1.42e-263	-	-	-	S	-	-	-	Predicted membrane protein (DUF2142)
HLNKLFDN_01476	7.39e-165	-	-	-	M	-	-	-	Cell wall-binding repeat protein
HLNKLFDN_01477	0.0	glfT	2.4.1.288	GT2	S	ko:K16650	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
HLNKLFDN_01478	7.38e-297	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HLNKLFDN_01479	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
HLNKLFDN_01480	5.94e-41	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HLNKLFDN_01481	2.71e-123	-	-	-	L	ko:K07450	-	ko00000	Resolvase, N terminal domain
HLNKLFDN_01482	1.09e-246	-	-	-	L	ko:K07496	-	ko00000	Helix-turn-helix domain
HLNKLFDN_01483	5.24e-258	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HLNKLFDN_01484	1.22e-31	-	-	-	S	-	-	-	Addiction module toxin, RelE StbE family
HLNKLFDN_01485	7.21e-24	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HLNKLFDN_01486	2.33e-85	-	-	-	-	-	-	-	-
HLNKLFDN_01487	1.43e-251	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HLNKLFDN_01488	4.54e-215	iunH2	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HLNKLFDN_01489	0.0	-	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
HLNKLFDN_01490	1.37e-224	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HLNKLFDN_01491	3.76e-244	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HLNKLFDN_01492	7.12e-62	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HLNKLFDN_01493	3.97e-107	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HLNKLFDN_01494	3.05e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HLNKLFDN_01495	1.16e-92	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HLNKLFDN_01497	2.6e-176	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HLNKLFDN_01499	4.7e-68	-	-	-	M	-	-	-	Protein of unknown function (DUF3152)
HLNKLFDN_01500	4.65e-269	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HLNKLFDN_01501	7.7e-89	-	-	-	-	-	-	-	-
HLNKLFDN_01502	2.91e-189	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HLNKLFDN_01503	1.66e-210	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
HLNKLFDN_01504	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HLNKLFDN_01505	1.3e-186	-	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	Heavy metal translocating P-type atpase
HLNKLFDN_01506	5.93e-263	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
HLNKLFDN_01507	8.52e-135	pyrE1	-	-	F	-	-	-	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HLNKLFDN_01508	7.3e-168	trmH	2.1.1.34	-	J	ko:K00556	-	ko00000,ko01000,ko03016	RNA methyltransferase TrmH family
HLNKLFDN_01509	6.91e-166	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HLNKLFDN_01510	1.35e-62	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLNKLFDN_01511	0.0	gatA	6.3.5.6, 6.3.5.7	-	F	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HLNKLFDN_01512	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLNKLFDN_01513	1.4e-261	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HLNKLFDN_01514	1.43e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF2469)
HLNKLFDN_01515	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
HLNKLFDN_01516	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HLNKLFDN_01517	1.09e-104	lrp_3	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	helix_turn_helix ASNC type
HLNKLFDN_01518	6.95e-91	tyrA	5.4.99.5	-	E	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
HLNKLFDN_01519	0.0	-	-	-	S	-	-	-	domain protein
HLNKLFDN_01520	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HLNKLFDN_01521	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HLNKLFDN_01522	3.89e-157	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HLNKLFDN_01523	1.1e-172	glnR	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
HLNKLFDN_01524	1.55e-173	-	-	-	-	-	-	-	-
HLNKLFDN_01525	1.22e-127	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HLNKLFDN_01526	2.28e-118	ppa	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HLNKLFDN_01527	0.0	glgE	2.4.99.16	GH13	G	ko:K16147	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
HLNKLFDN_01528	1.55e-223	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HLNKLFDN_01529	0.0	oxc	4.1.1.8	-	EH	ko:K01577	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Thiamine pyrophosphate enzyme, central domain
HLNKLFDN_01530	5.79e-248	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HLNKLFDN_01531	0.0	frc	2.8.3.15, 2.8.3.16	-	C	ko:K07544,ko:K07749	ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HLNKLFDN_01535	2.81e-63	-	-	-	-	-	-	-	-
HLNKLFDN_01538	1.15e-80	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	single-stranded DNA-binding protein
HLNKLFDN_01539	1.81e-61	-	-	-	-	-	-	-	-
HLNKLFDN_01541	1.54e-236	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	ParB-like nuclease domain
HLNKLFDN_01543	7.05e-64	-	-	-	V	-	-	-	HNH endonuclease
HLNKLFDN_01544	3.73e-30	-	-	-	A	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HLNKLFDN_01551	1.39e-63	-	-	-	-	-	-	-	-
HLNKLFDN_01553	1.82e-30	-	-	-	K	-	-	-	Helix-turn-helix domain
HLNKLFDN_01558	1.37e-63	-	-	-	L	-	-	-	HNH endonuclease
HLNKLFDN_01560	0.0	-	-	-	S	-	-	-	Terminase
HLNKLFDN_01561	1.14e-313	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HLNKLFDN_01562	7.71e-202	-	-	-	-	-	-	-	-
HLNKLFDN_01564	4.1e-63	-	-	-	-	-	-	-	-
HLNKLFDN_01565	6.17e-197	-	-	-	-	-	-	-	-
HLNKLFDN_01567	1.29e-59	-	-	-	S	-	-	-	Phage protein Gp19/Gp15/Gp42
HLNKLFDN_01571	4.68e-94	-	-	-	-	-	-	-	-
HLNKLFDN_01574	9.15e-141	-	-	-	S	-	-	-	phage tail tape measure protein
HLNKLFDN_01575	1.18e-238	-	-	-	S	-	-	-	Fibronectin type 3 domain
HLNKLFDN_01576	9.68e-129	-	-	-	-	-	-	-	-
HLNKLFDN_01579	7.78e-144	-	-	-	-	-	-	-	-
HLNKLFDN_01580	1.49e-96	-	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	reverse transcriptase
HLNKLFDN_01584	9.46e-248	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HLNKLFDN_01585	4.27e-36	-	-	-	-	-	-	-	-
HLNKLFDN_01586	2.6e-19	-	-	-	-	-	-	-	-
HLNKLFDN_01587	2.68e-120	-	-	-	L	-	-	-	Phage integrase family
HLNKLFDN_01589	1.2e-264	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HLNKLFDN_01590	6.89e-190	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HLNKLFDN_01591	9.64e-42	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HLNKLFDN_01592	6.4e-93	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HLNKLFDN_01593	2.31e-191	atpH	-	-	C	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HLNKLFDN_01594	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HLNKLFDN_01595	5.5e-210	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HLNKLFDN_01596	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HLNKLFDN_01597	2.85e-60	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HLNKLFDN_01598	1.32e-156	nucS	-	-	L	ko:K07503	-	ko00000,ko01000	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HLNKLFDN_01599	2.27e-192	-	5.2.1.8	-	M	ko:K01802	-	ko00000,ko01000	FKBP-type peptidyl-prolyl cis-trans isomerase
HLNKLFDN_01600	1.46e-264	-	-	-	-	-	-	-	-
HLNKLFDN_01601	1.33e-230	-	-	-	-	-	-	-	-
HLNKLFDN_01602	1.07e-215	ybbN	-	-	O	ko:K05838	-	ko00000,ko03110	Tetratricopeptide repeat
HLNKLFDN_01603	5.73e-156	-	-	-	S	-	-	-	CYTH
HLNKLFDN_01605	5.64e-84	psp1	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	Endoribonuclease L-PSP
HLNKLFDN_01606	0.0	-	-	-	E	ko:K16235	-	ko00000,ko02000	amino acid
HLNKLFDN_01607	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HLNKLFDN_01608	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HLNKLFDN_01609	3.73e-306	hom	1.1.1.3, 2.7.2.4	-	E	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HLNKLFDN_01610	1.58e-239	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HLNKLFDN_01611	0.0	maf	-	-	DF	ko:K06287	-	ko00000	Maf-like protein
HLNKLFDN_01612	4.07e-268	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HLNKLFDN_01613	0.0	araB	-	-	G	-	-	-	FGGY family of carbohydrate kinases, C-terminal domain
HLNKLFDN_01614	1.1e-167	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Class II Aldolase and Adducin N-terminal domain
HLNKLFDN_01615	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HLNKLFDN_01616	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HLNKLFDN_01617	0.0	-	-	-	V	ko:K06147,ko:K06148,ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter transmembrane region
HLNKLFDN_01618	6.62e-199	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HLNKLFDN_01619	8.19e-162	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HLNKLFDN_01620	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HLNKLFDN_01621	1.44e-205	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_01622	3.96e-230	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
HLNKLFDN_01623	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HLNKLFDN_01624	9.31e-251	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HLNKLFDN_01625	5.4e-309	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HLNKLFDN_01626	2.98e-212	-	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
HLNKLFDN_01627	2.87e-154	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
HLNKLFDN_01628	5.83e-310	-	-	-	T	-	-	-	Diguanylate cyclase (GGDEF) domain protein
HLNKLFDN_01629	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
HLNKLFDN_01630	2.52e-63	-	-	-	-	-	-	-	-
HLNKLFDN_01631	4.67e-234	staP	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
HLNKLFDN_01632	2.78e-112	etp	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
HLNKLFDN_01633	5.39e-283	-	-	-	S	-	-	-	Protein of unknown function (DUF4012)
HLNKLFDN_01634	4.65e-255	wcoI	-	-	DM	-	-	-	Psort location CytoplasmicMembrane, score
HLNKLFDN_01635	8.96e-27	-	-	-	-	-	-	-	-
HLNKLFDN_01636	1.81e-149	-	-	-	-	-	-	-	-
HLNKLFDN_01637	1.07e-50	-	-	-	V	-	-	-	Abi-like protein
HLNKLFDN_01638	0.0	-	-	-	O	-	-	-	Subtilase family
HLNKLFDN_01639	8.09e-185	-	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
HLNKLFDN_01640	2.16e-16	-	-	-	S	-	-	-	YjzC-like protein
HLNKLFDN_01642	3.36e-170	-	-	-	G	-	-	-	Acyltransferase family
HLNKLFDN_01643	1.9e-279	rfbX	-	-	S	ko:K03328,ko:K18799	-	ko00000,ko01005,ko02000	polysaccharide biosynthetic process
HLNKLFDN_01644	4.92e-242	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.87
HLNKLFDN_01645	7.88e-268	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
HLNKLFDN_01646	9.04e-248	-	2.7.8.12	-	S	ko:K09809	-	ko00000,ko01000	Glycosyltransferase like family 2
HLNKLFDN_01648	1.06e-175	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HLNKLFDN_01649	1.51e-186	-	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.87
HLNKLFDN_01650	5.91e-120	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
HLNKLFDN_01652	4.3e-131	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HLNKLFDN_01653	1.43e-76	cysE_1	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	serine acetyltransferase
HLNKLFDN_01654	5.69e-100	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
HLNKLFDN_01655	1.46e-275	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HLNKLFDN_01656	2.22e-295	-	1.12.98.1	-	C	ko:K00441	ko00680,ko01100,ko01120,map00680,map01100,map01120	ko00000,ko00001,ko01000	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term
HLNKLFDN_01657	1.95e-69	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.87
HLNKLFDN_01658	9.6e-26	-	-	-	I	-	-	-	Acyltransferase family
HLNKLFDN_01660	3.23e-59	-	-	-	-	-	-	-	-
HLNKLFDN_01661	3.01e-56	-	-	-	-	-	-	-	-
HLNKLFDN_01663	1.17e-33	-	-	-	L	-	-	-	transposition
HLNKLFDN_01664	5.46e-45	-	-	-	L	-	-	-	PFAM Integrase catalytic
HLNKLFDN_01665	4.91e-45	-	-	-	L	-	-	-	Transposase
HLNKLFDN_01666	3.2e-86	-	-	-	-	-	-	-	-
HLNKLFDN_01667	2.91e-110	-	-	-	-	-	-	-	-
HLNKLFDN_01668	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HLNKLFDN_01669	2.29e-188	-	-	-	V	-	-	-	Abi-like protein
HLNKLFDN_01670	5.79e-73	yccF	-	-	S	-	-	-	Inner membrane component domain
HLNKLFDN_01671	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
HLNKLFDN_01672	1.49e-185	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_01673	4.31e-207	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HLNKLFDN_01674	6.19e-284	-	-	-	G	ko:K02027,ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HLNKLFDN_01675	9.06e-233	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HLNKLFDN_01676	1.63e-234	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HLNKLFDN_01677	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HLNKLFDN_01678	7.52e-207	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_01679	1.28e-187	-	-	-	P	ko:K02026,ko:K10190	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_01680	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
HLNKLFDN_01681	0.0	-	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HLNKLFDN_01682	1.91e-09	wcoI	-	-	DM	-	-	-	Psort location CytoplasmicMembrane, score
HLNKLFDN_01683	3.03e-10	wcoI	-	-	DM	-	-	-	Psort location CytoplasmicMembrane, score
HLNKLFDN_01684	7.02e-114	-	-	-	-	-	-	-	-
HLNKLFDN_01685	2.76e-223	-	-	-	S	ko:K21688	-	ko00000	G5
HLNKLFDN_01686	4.09e-80	trxA	1.8.1.9	-	O	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	ko00000,ko00001,ko01000,ko03110	Belongs to the thioredoxin family
HLNKLFDN_01687	2.28e-146	-	-	-	F	-	-	-	Domain of unknown function (DUF4916)
HLNKLFDN_01688	1.3e-205	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HLNKLFDN_01689	1.2e-264	nudC	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
HLNKLFDN_01690	1.36e-91	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HLNKLFDN_01691	3.57e-300	-	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2183)
HLNKLFDN_01692	0.0	ptrB	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Peptidase, S9A B C family, catalytic domain protein
HLNKLFDN_01693	3.92e-246	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HLNKLFDN_01694	1.19e-115	-	-	-	J	-	-	-	TM2 domain
HLNKLFDN_01695	6.79e-271	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
HLNKLFDN_01696	7.43e-171	crp	-	-	K	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HLNKLFDN_01697	0.0	pon1	-	-	M	-	-	-	Transglycosylase
HLNKLFDN_01698	1.69e-279	namA	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
HLNKLFDN_01699	1.65e-288	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
HLNKLFDN_01700	1.13e-181	-	-	-	K	-	-	-	DeoR C terminal sensor domain
HLNKLFDN_01701	9.99e-317	galT	2.7.7.12	-	C	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, N-terminal domain
HLNKLFDN_01702	1.45e-297	galK	2.7.1.6, 2.7.7.12	-	G	ko:K00849,ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
HLNKLFDN_01703	7.17e-29	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Drug resistance MFS transporter, drug H antiporter-2 family
HLNKLFDN_01704	1.32e-57	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HLNKLFDN_01705	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HLNKLFDN_01706	1.11e-162	spoU	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HLNKLFDN_01707	1e-229	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	FES
HLNKLFDN_01708	1e-137	-	-	-	-	-	-	-	-
HLNKLFDN_01709	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLNKLFDN_01710	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLNKLFDN_01711	2.12e-128	-	-	-	T	-	-	-	Forkhead associated domain
HLNKLFDN_01712	4.63e-150	-	-	-	B	-	-	-	Belongs to the OprB family
HLNKLFDN_01713	8.17e-209	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
HLNKLFDN_01714	0.0	-	-	-	E	-	-	-	Transglutaminase-like superfamily
HLNKLFDN_01715	1.34e-281	-	-	-	S	-	-	-	Protein of unknown function DUF58
HLNKLFDN_01716	1.28e-300	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HLNKLFDN_01717	0.0	-	-	-	S	-	-	-	Fibronectin type 3 domain
HLNKLFDN_01718	0.0	pknK	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HLNKLFDN_01719	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
HLNKLFDN_01720	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	Belongs to the helicase family. UvrD subfamily
HLNKLFDN_01721	6.64e-313	-	-	-	G	-	-	-	Major Facilitator Superfamily
HLNKLFDN_01722	4.54e-171	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HLNKLFDN_01723	1.6e-50	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
HLNKLFDN_01724	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HLNKLFDN_01725	4.1e-223	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HLNKLFDN_01726	0.0	rnj	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HLNKLFDN_01728	0.0	pepN	3.4.11.2	-	E	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Peptidase family M1 domain
HLNKLFDN_01729	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HLNKLFDN_01730	7.79e-157	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HLNKLFDN_01731	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HLNKLFDN_01732	3.02e-20	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HLNKLFDN_01733	5.77e-180	-	-	-	-	-	-	-	-
HLNKLFDN_01734	1.08e-223	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HLNKLFDN_01735	4.1e-287	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter family protein
HLNKLFDN_01736	1.54e-220	-	-	-	C	ko:K07138	-	ko00000	Domain of unknown function (DUF362)
HLNKLFDN_01737	3.76e-145	-	-	-	F	-	-	-	uridine kinase
HLNKLFDN_01738	5.81e-119	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HLNKLFDN_01739	2.6e-176	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
HLNKLFDN_01740	1.34e-181	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HLNKLFDN_01741	8.16e-203	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HLNKLFDN_01742	4.09e-290	rutG	-	-	F	ko:K02824,ko:K03458	-	ko00000,ko02000	Permease family
HLNKLFDN_01743	3.13e-163	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
HLNKLFDN_01744	0.0	-	-	-	JKL	-	-	-	helicase superfamily c-terminal domain
HLNKLFDN_01745	4.75e-173	-	-	-	V	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HLNKLFDN_01746	1.17e-173	-	-	-	V	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HLNKLFDN_01747	2.22e-311	-	-	-	S	-	-	-	Putative esterase
HLNKLFDN_01748	0.0	lysX	-	-	S	-	-	-	Uncharacterised conserved protein (DUF2156)
HLNKLFDN_01749	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HLNKLFDN_01750	3.15e-299	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
HLNKLFDN_01751	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HLNKLFDN_01752	6.8e-227	opcA	-	-	G	-	-	-	Glucose-6-phosphate dehydrogenase subunit
HLNKLFDN_01753	1.67e-186	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
HLNKLFDN_01754	3.28e-105	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HLNKLFDN_01755	4.96e-134	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HLNKLFDN_01756	5.37e-181	-	-	-	E	-	-	-	AzlC protein
HLNKLFDN_01757	1.96e-71	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
HLNKLFDN_01758	0.0	cstA	-	-	T	ko:K06200	-	ko00000	5TM C-terminal transporter carbon starvation CstA
HLNKLFDN_01759	1.2e-53	-	-	-	S	-	-	-	Selenoprotein, putative
HLNKLFDN_01760	3.73e-228	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
HLNKLFDN_01761	0.0	-	-	-	S	ko:K09118	-	ko00000	Uncharacterised protein family (UPF0182)
HLNKLFDN_01762	1.26e-120	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HLNKLFDN_01763	1.42e-145	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HLNKLFDN_01764	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HLNKLFDN_01765	7.13e-313	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HLNKLFDN_01766	4.86e-97	-	-	-	D	-	-	-	Septum formation initiator
HLNKLFDN_01767	1.37e-133	-	-	-	S	ko:K09009	-	ko00000	Protein of unknown function (DUF501)
HLNKLFDN_01768	3.69e-232	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
HLNKLFDN_01770	1.2e-88	-	-	-	P	-	-	-	Major Facilitator Superfamily
HLNKLFDN_01772	9.11e-120	-	-	-	-	-	-	-	-
HLNKLFDN_01773	0.0	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
HLNKLFDN_01774	1.12e-95	fkbP	5.2.1.8	-	G	ko:K01802	-	ko00000,ko01000	Peptidyl-prolyl cis-trans
HLNKLFDN_01775	2.04e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HLNKLFDN_01776	6.91e-203	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
HLNKLFDN_01777	0.0	pdtaS	2.7.13.3	-	T	ko:K00936	-	ko00000,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HLNKLFDN_01778	3.32e-61	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HLNKLFDN_01779	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
HLNKLFDN_01780	5.33e-216	lytR2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HLNKLFDN_01782	2.38e-299	yvhJ	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HLNKLFDN_01783	5.69e-72	whiB2	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HLNKLFDN_01784	0.0	-	-	-	S	-	-	-	Glycosyl transferase, family 2
HLNKLFDN_01785	1.26e-288	-	-	-	-	-	-	-	-
HLNKLFDN_01786	6.14e-93	-	-	-	S	-	-	-	Zincin-like metallopeptidase
HLNKLFDN_01787	2.56e-196	-	-	-	T	-	-	-	Eukaryotic phosphomannomutase
HLNKLFDN_01788	2.31e-178	pyrE_1	-	-	S	-	-	-	Phosphoribosyl transferase domain
HLNKLFDN_01789	1.99e-238	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HLNKLFDN_01790	1.17e-163	cseB	-	-	T	-	-	-	Response regulator receiver domain protein
HLNKLFDN_01791	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HLNKLFDN_01792	8.46e-133	carD	-	-	K	ko:K07736	-	ko00000,ko03000	CarD-like/TRCF domain
HLNKLFDN_01793	3.22e-114	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HLNKLFDN_01794	3.19e-179	znuB	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
HLNKLFDN_01795	7.98e-205	-	-	-	P	ko:K02074	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HLNKLFDN_01796	1.55e-235	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
HLNKLFDN_01797	9.54e-208	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HLNKLFDN_01798	0.0	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HLNKLFDN_01799	1.09e-149	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HLNKLFDN_01800	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HLNKLFDN_01802	2.25e-202	terC	-	-	P	ko:K05794	-	ko00000	Integral membrane protein, TerC family
HLNKLFDN_01803	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
HLNKLFDN_01805	1.44e-25	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HLNKLFDN_01807	8.69e-249	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HLNKLFDN_01808	3.03e-147	ehuA	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HLNKLFDN_01809	7.84e-159	-	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Bacterial periplasmic substrate-binding proteins
HLNKLFDN_01810	7.45e-131	tcyA/tcyB	-	-	E	ko:K02029,ko:K02030,ko:K02424,ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_01811	1.68e-44	-	-	-	F	-	-	-	DNA helicase
HLNKLFDN_01812	0.0	-	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HLNKLFDN_01813	2.72e-307	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	HsdM N-terminal domain
HLNKLFDN_01814	1.66e-59	-	-	-	-	-	-	-	-
HLNKLFDN_01815	4.57e-102	nfrA	-	-	C	-	-	-	Nitroreductase family
HLNKLFDN_01816	1.74e-50	nfrA	-	-	C	-	-	-	Nitroreductase family
HLNKLFDN_01817	4.34e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF4235)
HLNKLFDN_01818	2.83e-176	gpm2	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
HLNKLFDN_01819	0.0	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HLNKLFDN_01820	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
HLNKLFDN_01821	4.75e-227	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
HLNKLFDN_01822	2.27e-224	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HLNKLFDN_01823	7.45e-197	msmF	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_01824	1.75e-193	-	-	-	G	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLNKLFDN_01825	3.46e-137	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HLNKLFDN_01826	1.16e-140	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Peptidase family S51
HLNKLFDN_01827	3.22e-18	-	-	-	S	-	-	-	Transposon-encoded protein TnpV
HLNKLFDN_01828	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
HLNKLFDN_01829	0.0	apuB	3.2.1.41, 3.2.1.68	CBM48,GH13	G	ko:K01200,ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
HLNKLFDN_01830	8.69e-186	-	-	-	S	ko:K07025	-	ko00000	HAD-hyrolase-like
HLNKLFDN_01831	1.02e-178	traX	-	-	S	-	-	-	TraX protein
HLNKLFDN_01832	3.91e-244	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HLNKLFDN_01833	1.29e-06	-	-	-	K	-	-	-	Transcriptional regulator
HLNKLFDN_01834	5.66e-200	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HLNKLFDN_01835	3.01e-176	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HLNKLFDN_01836	2.89e-151	strK	3.1.3.1, 3.1.3.39	-	P	ko:K01077,ko:K04342	ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
HLNKLFDN_01837	5.66e-187	-	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
HLNKLFDN_01838	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HLNKLFDN_01839	1.29e-92	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HLNKLFDN_01840	1.14e-232	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	DnaJ molecular chaperone homology domain
HLNKLFDN_01841	3.11e-144	hspR	-	-	K	ko:K13640	-	ko00000,ko03000	transcriptional regulator, MerR family
HLNKLFDN_01842	6.08e-63	-	-	-	-	-	-	-	-
HLNKLFDN_01843	1.69e-166	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
HLNKLFDN_01845	1.1e-161	dedA1	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HLNKLFDN_01846	6.95e-22	-	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Glycosyl hydrolase family 26
HLNKLFDN_01847	3.89e-240	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HLNKLFDN_01848	1.32e-137	-	-	-	-	-	-	-	-
HLNKLFDN_01849	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HLNKLFDN_01850	0.0	lacZ3	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HLNKLFDN_01851	5.26e-174	-	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP)
HLNKLFDN_01852	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HLNKLFDN_01853	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HLNKLFDN_01854	2.87e-269	-	-	-	GK	-	-	-	ROK family
HLNKLFDN_01855	1.5e-304	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HLNKLFDN_01856	1.55e-195	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLNKLFDN_01857	1.13e-220	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
HLNKLFDN_01858	5.59e-221	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HLNKLFDN_01859	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
HLNKLFDN_01860	1.29e-190	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HLNKLFDN_01861	2.55e-293	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
HLNKLFDN_01862	9.79e-240	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HLNKLFDN_01863	0.0	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HLNKLFDN_01864	0.0	-	3.2.1.14	GH18	S	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Carbohydrate binding domain
HLNKLFDN_01865	0.0	-	-	-	M	-	-	-	probably involved in cell wall
HLNKLFDN_01866	1.6e-296	-	-	-	M	-	-	-	Protein of unknown function (DUF2961)
HLNKLFDN_01867	7.8e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HLNKLFDN_01869	1.48e-271	-	-	-	I	-	-	-	Hydrolase, alpha beta domain protein
HLNKLFDN_01870	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HLNKLFDN_01871	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HLNKLFDN_01872	6.8e-162	-	-	-	-	-	-	-	-
HLNKLFDN_01873	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HLNKLFDN_01874	2.55e-288	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HLNKLFDN_01875	6.54e-294	-	-	-	G	-	-	-	Alpha galactosidase A
HLNKLFDN_01876	0.0	-	-	-	G	-	-	-	Alpha-L-arabinofuranosidase C-terminus
HLNKLFDN_01877	3.43e-235	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
HLNKLFDN_01878	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HLNKLFDN_01879	1.17e-214	-	-	-	S	-	-	-	Glutamine amidotransferase domain
HLNKLFDN_01880	7.79e-193	-	-	-	T	ko:K06950	-	ko00000	HD domain
HLNKLFDN_01881	2.29e-236	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HLNKLFDN_01882	2.67e-308	-	-	-	V	-	-	-	ABC transporter permease
HLNKLFDN_01883	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HLNKLFDN_01884	1.22e-138	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
HLNKLFDN_01885	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
HLNKLFDN_01886	2.13e-293	-	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
HLNKLFDN_01887	6.69e-55	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HLNKLFDN_01888	3.46e-18	-	-	-	S	-	-	-	Psort location Extracellular, score 8.82
HLNKLFDN_01889	1.03e-159	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HLNKLFDN_01890	3.81e-305	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HLNKLFDN_01891	7.08e-273	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HLNKLFDN_01892	3.56e-145	vex	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLNKLFDN_01893	1e-103	ypeA	2.3.1.1	-	K	ko:K22477	ko00220,ko01210,ko01230,map00220,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
HLNKLFDN_01894	8.25e-155	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Psort location CytoplasmicMembrane, score
HLNKLFDN_01895	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
HLNKLFDN_01896	3.81e-127	-	-	-	S	-	-	-	GtrA-like protein
HLNKLFDN_01897	0.0	-	-	-	S	-	-	-	LPXTG-motif cell wall anchor domain protein
HLNKLFDN_01898	1.64e-227	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HLNKLFDN_01899	1.71e-201	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HLNKLFDN_01900	3.34e-173	-	-	-	-	-	-	-	-
HLNKLFDN_01901	2.72e-63	-	-	-	S	ko:K07133	-	ko00000	Psort location Cytoplasmic, score
HLNKLFDN_01902	1.32e-270	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
HLNKLFDN_01903	2.2e-140	-	-	-	-	-	-	-	-
HLNKLFDN_01904	6.14e-315	-	-	-	T	-	-	-	GHKL domain
HLNKLFDN_01905	4.34e-169	-	-	-	K	-	-	-	LytTr DNA-binding domain
HLNKLFDN_01906	1.26e-268	ugpC	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HLNKLFDN_01907	0.0	-	-	-	KLT	-	-	-	Domain of unknown function (DUF4032)
HLNKLFDN_01908	1.48e-223	rlmB	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLNKLFDN_01909	3.2e-293	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HLNKLFDN_01910	6.49e-19	-	-	-	S	-	-	-	Psort location Extracellular, score 8.82
HLNKLFDN_01911	1.44e-72	-	-	-	DJ	ko:K06218	-	ko00000,ko02048	Addiction module toxin, RelE StbE family
HLNKLFDN_01912	1.94e-66	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HLNKLFDN_01913	4.53e-191	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HLNKLFDN_01914	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HLNKLFDN_01915	0.0	pacL2	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HLNKLFDN_01916	1.99e-109	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain