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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
NADHPLIE_00001	4.88e-150	-	-	-	G	ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
NADHPLIE_00002	3.58e-20	-	-	-	G	ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
NADHPLIE_00003	5.49e-237	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
NADHPLIE_00004	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
NADHPLIE_00006	1.12e-209	-	-	-	S	-	-	-	Glutamine amidotransferase domain
NADHPLIE_00007	2.81e-177	-	-	-	T	ko:K06950	-	ko00000	HD domain
NADHPLIE_00008	5.02e-259	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NADHPLIE_00009	3.31e-315	-	-	-	V	-	-	-	ABC transporter permease
NADHPLIE_00010	0.0	-	-	-	H	-	-	-	Protein of unknown function (DUF4012)
NADHPLIE_00011	9.79e-16	-	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferase family 2
NADHPLIE_00012	1.01e-172	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
NADHPLIE_00013	4.29e-221	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
NADHPLIE_00014	1.93e-211	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NADHPLIE_00015	3.42e-37	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	ThiS family
NADHPLIE_00016	6.84e-97	-	-	-	-	-	-	-	-
NADHPLIE_00017	1.91e-242	-	-	-	-	-	-	-	-
NADHPLIE_00018	7.47e-267	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
NADHPLIE_00019	7.49e-65	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NADHPLIE_00021	5.44e-139	-	-	-	-	-	-	-	-
NADHPLIE_00022	1.64e-256	mutT	3.6.1.55	-	LT	ko:K03574	-	ko00000,ko01000,ko03400	Phosphoglycerate mutase family
NADHPLIE_00023	1.93e-133	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NADHPLIE_00024	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NADHPLIE_00026	8.79e-167	-	-	-	D	-	-	-	bacterial-type flagellum organization
NADHPLIE_00027	1.93e-243	cpaF	-	-	U	ko:K02283	-	ko00000,ko02035,ko02044	Type II IV secretion system protein
NADHPLIE_00028	2.62e-157	-	-	-	U	ko:K12510	-	ko00000,ko02044	Type ii secretion system
NADHPLIE_00030	9.07e-91	-	-	-	NU	-	-	-	Type II secretion system (T2SS), protein F
NADHPLIE_00031	3.96e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF4244)
NADHPLIE_00032	8.29e-61	-	-	-	U	-	-	-	TadE-like protein
NADHPLIE_00033	3.62e-73	-	-	-	S	-	-	-	TIGRFAM helicase secretion neighborhood TadE-like protein
NADHPLIE_00034	1.61e-274	-	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Diacylglycerol kinase catalytic domain protein
NADHPLIE_00035	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III subunit gamma tau
NADHPLIE_00036	1.26e-33	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III subunit gamma tau
NADHPLIE_00037	1.21e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NADHPLIE_00038	2.29e-176	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
NADHPLIE_00039	1.42e-126	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
NADHPLIE_00041	7.91e-271	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NADHPLIE_00042	1.77e-148	-	-	-	-	-	-	-	-
NADHPLIE_00043	0.0	-	2.7.11.1	-	S	ko:K12132	-	ko00000,ko01000,ko01001	PASTA domain
NADHPLIE_00044	1.29e-24	-	2.7.11.1	-	S	ko:K12132	-	ko00000,ko01000,ko01001	PASTA domain
NADHPLIE_00045	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NADHPLIE_00046	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NADHPLIE_00047	0.0	pbp5	-	-	M	-	-	-	Transglycosylase
NADHPLIE_00048	1.27e-295	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
NADHPLIE_00049	6.63e-175	-	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
NADHPLIE_00050	7.33e-144	-	-	-	M	-	-	-	PA domain
NADHPLIE_00051	0.0	-	-	-	M	-	-	-	PA domain
NADHPLIE_00052	2.59e-230	-	-	-	M	-	-	-	PA domain
NADHPLIE_00053	1.87e-250	-	-	-	I	-	-	-	PAP2 superfamily
NADHPLIE_00054	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NADHPLIE_00055	2.08e-158	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NADHPLIE_00056	3.5e-271	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NADHPLIE_00057	8.04e-257	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NADHPLIE_00058	1.47e-50	hpr	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
NADHPLIE_00059	5.64e-71	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NADHPLIE_00060	1.35e-276	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NADHPLIE_00062	2.62e-114	-	-	-	S	-	-	-	Fic/DOC family
NADHPLIE_00063	2.47e-145	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NADHPLIE_00064	4.3e-89	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NADHPLIE_00065	8.33e-31	-	-	-	G	-	-	-	MFS/sugar transport protein
NADHPLIE_00066	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	Iron permease FTR1 family
NADHPLIE_00067	2.38e-150	-	-	-	P	ko:K07230	-	ko00000,ko02000	Fe2+ transport protein
NADHPLIE_00068	2.91e-294	-	-	-	S	-	-	-	Predicted membrane protein (DUF2318)
NADHPLIE_00069	9.25e-289	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
NADHPLIE_00070	1.2e-270	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NADHPLIE_00071	1.1e-190	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NADHPLIE_00072	8.08e-103	-	-	-	S	-	-	-	FMN_bind
NADHPLIE_00073	1.5e-167	-	-	-	K	ko:K03489,ko:K03710	-	ko00000,ko03000	UTRA
NADHPLIE_00074	3.94e-87	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
NADHPLIE_00075	0.0	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NADHPLIE_00076	5.95e-65	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NADHPLIE_00077	1.29e-66	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
NADHPLIE_00078	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
NADHPLIE_00079	9e-142	-	-	-	-	-	-	-	-
NADHPLIE_00080	3.23e-307	-	-	-	S	-	-	-	Putative ABC-transporter type IV
NADHPLIE_00081	1.65e-207	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NADHPLIE_00083	4.25e-229	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
NADHPLIE_00084	0.0	-	-	-	M	ko:K20276	ko02024,map02024	ko00000,ko00001	chlorophyll binding
NADHPLIE_00085	0.0	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
NADHPLIE_00087	2.2e-104	-	-	-	K	-	-	-	Winged helix DNA-binding domain
NADHPLIE_00088	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NADHPLIE_00089	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
NADHPLIE_00090	2.35e-106	-	-	-	-	-	-	-	-
NADHPLIE_00091	5.66e-24	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
NADHPLIE_00093	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
NADHPLIE_00094	0.0	-	-	-	S	-	-	-	Glycosyl hydrolases related to GH101 family, GH129
NADHPLIE_00095	6.85e-255	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyltransferase like family 2
NADHPLIE_00096	1.17e-172	icaR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NADHPLIE_00098	6.41e-192	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NADHPLIE_00099	6.01e-305	amt	-	-	U	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
NADHPLIE_00100	2.56e-72	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Nitrogen regulatory protein P-II
NADHPLIE_00101	0.0	glnD	2.7.7.59	-	O	ko:K00990	ko02020,map02020	ko00000,ko00001,ko01000	Nucleotidyltransferase domain
NADHPLIE_00103	0.0	dinF	-	-	V	-	-	-	MatE
NADHPLIE_00104	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
NADHPLIE_00105	0.0	murE	-	-	M	-	-	-	Domain of unknown function (DUF1727)
NADHPLIE_00106	1.02e-181	cobQ2	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
NADHPLIE_00107	3.15e-44	-	-	-	S	-	-	-	granule-associated protein
NADHPLIE_00108	0.0	-	-	-	S	ko:K03688	-	ko00000	ABC1 family
NADHPLIE_00109	7.54e-158	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
NADHPLIE_00110	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
NADHPLIE_00111	5.65e-57	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
NADHPLIE_00112	2.51e-298	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
NADHPLIE_00113	2.47e-164	pyrE1	-	-	F	-	-	-	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NADHPLIE_00114	5.56e-213	trmH	2.1.1.34	-	J	ko:K00556	-	ko00000,ko01000,ko03016	RNA methyltransferase TrmH family
NADHPLIE_00115	4.41e-80	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NADHPLIE_00116	3.98e-111	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NADHPLIE_00117	3.33e-64	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NADHPLIE_00118	0.0	gatA	6.3.5.6, 6.3.5.7	-	F	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NADHPLIE_00119	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NADHPLIE_00120	1.96e-251	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NADHPLIE_00121	6.51e-69	-	-	-	S	-	-	-	Protein of unknown function (DUF2469)
NADHPLIE_00122	8.95e-173	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
NADHPLIE_00123	1.15e-148	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
NADHPLIE_00124	1.17e-313	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NADHPLIE_00125	2.87e-63	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NADHPLIE_00126	1.13e-218	-	2.6.1.1	-	E	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
NADHPLIE_00127	7.67e-118	lrp_3	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	helix_turn_helix ASNC type
NADHPLIE_00128	1.95e-88	tyrA	5.4.99.5	-	E	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
NADHPLIE_00129	0.0	-	-	-	S	-	-	-	domain protein
NADHPLIE_00130	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NADHPLIE_00131	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
NADHPLIE_00132	4.88e-161	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NADHPLIE_00133	1.71e-169	glnR	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
NADHPLIE_00134	5.6e-170	-	-	-	-	-	-	-	-
NADHPLIE_00135	7.24e-130	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
NADHPLIE_00137	1.13e-118	ppa	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NADHPLIE_00138	0.0	glgE	2.4.99.16	GH13	G	ko:K16147	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
NADHPLIE_00139	1.06e-139	-	-	-	K	-	-	-	RNA polymerase II activating transcription factor binding
NADHPLIE_00140	0.0	-	-	-	K	-	-	-	RNA polymerase II activating transcription factor binding
NADHPLIE_00141	2.63e-48	-	-	-	-	-	-	-	-
NADHPLIE_00143	2.94e-265	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NADHPLIE_00144	3.54e-188	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
NADHPLIE_00146	1.21e-40	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NADHPLIE_00147	1.06e-97	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NADHPLIE_00148	1.62e-191	atpH	-	-	C	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NADHPLIE_00149	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NADHPLIE_00150	6.43e-212	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NADHPLIE_00151	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NADHPLIE_00152	5.65e-66	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
NADHPLIE_00153	3.84e-169	nucS	-	-	L	ko:K07503	-	ko00000,ko01000	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
NADHPLIE_00154	8.27e-187	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
NADHPLIE_00155	0.0	-	-	-	-	-	-	-	-
NADHPLIE_00156	3.74e-193	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
NADHPLIE_00157	1.56e-100	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
NADHPLIE_00158	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase L chain, ATP binding domain protein
NADHPLIE_00159	9.97e-15	pccB	-	-	I	-	-	-	Carboxyl transferase domain
NADHPLIE_00160	3.41e-39	pccB	-	-	I	-	-	-	Carboxyl transferase domain
NADHPLIE_00161	5.37e-293	pccB	-	-	I	-	-	-	Carboxyl transferase domain
NADHPLIE_00162	4.3e-53	fas	-	-	I	ko:K11533	ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931	ko00000,ko00001,ko00002,ko01000,ko01004	Beta-ketoacyl synthase, C-terminal domain
NADHPLIE_00163	0.0	fas	-	-	I	ko:K11533	ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931	ko00000,ko00001,ko00002,ko01000,ko01004	Beta-ketoacyl synthase, C-terminal domain
NADHPLIE_00165	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NADHPLIE_00166	8.76e-124	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NADHPLIE_00167	1.11e-299	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NADHPLIE_00168	1.47e-303	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin kinase
NADHPLIE_00169	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NADHPLIE_00170	4.66e-140	-	-	-	-	-	-	-	-
NADHPLIE_00171	5.18e-07	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
NADHPLIE_00172	1.28e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NADHPLIE_00173	3.57e-260	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NADHPLIE_00174	6.6e-64	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylglucosaminidase
NADHPLIE_00175	0.0	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylglucosaminidase
NADHPLIE_00176	4.04e-129	merA	1.16.1.1	-	C	ko:K00520,ko:K21739	-	ko00000,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NADHPLIE_00177	6.6e-156	merA	1.16.1.1	-	C	ko:K00520,ko:K21739	-	ko00000,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NADHPLIE_00178	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
NADHPLIE_00179	1.72e-90	-	-	-	M	-	-	-	Spy0128-like isopeptide containing domain
NADHPLIE_00180	2.26e-05	-	-	-	O	ko:K18546	-	ko00000,ko01000,ko01002	Peptidase s1 and s6 chymotrypsin hap
NADHPLIE_00183	5.8e-238	ptsG	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system, glucose-specific IIABC component
NADHPLIE_00184	1.2e-76	ptsG	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system, glucose-specific IIABC component
NADHPLIE_00185	5e-123	ptsG	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system, glucose-specific IIABC component
NADHPLIE_00186	5.06e-198	arbG	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
NADHPLIE_00187	3.25e-273	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
NADHPLIE_00188	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
NADHPLIE_00189	9.17e-297	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
NADHPLIE_00190	1.5e-55	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
NADHPLIE_00191	1.27e-302	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NADHPLIE_00193	0.0	-	3.2.1.50	-	G	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
NADHPLIE_00195	3.45e-120	-	-	-	-	-	-	-	-
NADHPLIE_00196	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NADHPLIE_00197	7.54e-240	opcA	-	-	G	-	-	-	Glucose-6-phosphate dehydrogenase subunit
NADHPLIE_00198	1.43e-181	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
NADHPLIE_00200	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NADHPLIE_00201	1.35e-162	tcsR3	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
NADHPLIE_00202	0.0	tcsS3	-	-	KT	-	-	-	PspC domain
NADHPLIE_00203	3.71e-270	pspC	-	-	KT	-	-	-	PspC domain
NADHPLIE_00204	7.07e-95	pspC	-	-	KT	-	-	-	PspC domain
NADHPLIE_00205	9.16e-196	-	-	-	-	-	-	-	-
NADHPLIE_00206	3.07e-142	-	-	-	S	-	-	-	Protein of unknown function (DUF4125)
NADHPLIE_00207	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4037)
NADHPLIE_00208	3.46e-71	-	-	-	EGP	ko:K08156,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
NADHPLIE_00209	4.62e-184	-	-	-	EGP	ko:K08156,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
NADHPLIE_00211	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
NADHPLIE_00212	6.8e-223	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
NADHPLIE_00213	9.96e-189	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NADHPLIE_00215	9.33e-153	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
NADHPLIE_00216	6.51e-288	senX3	2.7.13.3	-	T	ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NADHPLIE_00217	4.6e-53	-	-	-	-	-	-	-	-
NADHPLIE_00218	1.28e-275	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NADHPLIE_00219	4.11e-229	-	-	-	S	-	-	-	CHAP domain
NADHPLIE_00220	3.15e-86	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
NADHPLIE_00221	1.31e-244	-	-	-	T	-	-	-	Universal stress protein family
NADHPLIE_00222	4.35e-94	-	-	-	O	-	-	-	OsmC-like protein
NADHPLIE_00223	4.99e-223	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NADHPLIE_00224	5.46e-165	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dihydrofolate reductase
NADHPLIE_00225	2e-125	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	low molecular weight
NADHPLIE_00226	4.43e-250	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
NADHPLIE_00227	3.74e-58	-	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
NADHPLIE_00228	3.56e-145	vex	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NADHPLIE_00229	1.94e-270	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
NADHPLIE_00230	2.61e-58	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
NADHPLIE_00231	1.12e-211	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
NADHPLIE_00232	2e-09	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
NADHPLIE_00233	4.81e-236	-	-	-	-	-	-	-	-
NADHPLIE_00234	6.72e-140	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NADHPLIE_00235	6.53e-182	-	-	-	V	-	-	-	N-Acetylmuramoyl-L-alanine amidase
NADHPLIE_00236	1.64e-138	-	-	-	-	-	-	-	-
NADHPLIE_00237	5.05e-153	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
NADHPLIE_00238	2.44e-302	-	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NADHPLIE_00239	1.21e-234	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
NADHPLIE_00240	2.56e-31	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
NADHPLIE_00241	2.49e-28	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
NADHPLIE_00242	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
NADHPLIE_00243	0.0	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NADHPLIE_00244	2.25e-47	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NADHPLIE_00245	8.02e-216	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NADHPLIE_00246	1.4e-234	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NADHPLIE_00247	2.51e-56	pacL	3.6.3.8, 3.6.3.9	-	P	ko:K01537,ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	ko00000,ko00001,ko01000,ko04147	ATPase, P-type transporting, HAD superfamily, subfamily IC
NADHPLIE_00248	5.33e-237	-	-	-	T	-	-	-	Histidine kinase
NADHPLIE_00249	2.67e-154	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
NADHPLIE_00250	2e-149	-	-	-	P	ko:K07220	-	ko00000	Protein of unknown function DUF47
NADHPLIE_00251	1.47e-67	pitB	-	-	P	ko:K03306	-	ko00000	Phosphate transporter family
NADHPLIE_00252	3.75e-158	pitB	-	-	P	ko:K03306	-	ko00000	Phosphate transporter family
NADHPLIE_00253	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
NADHPLIE_00254	2.36e-233	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
NADHPLIE_00255	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
NADHPLIE_00257	3.68e-68	-	-	-	-	-	-	-	-
NADHPLIE_00258	1.46e-37	-	-	-	-	-	-	-	-
NADHPLIE_00259	8.37e-145	-	-	-	S	-	-	-	Protein of unknown function (DUF1294)
NADHPLIE_00262	6.9e-158	-	-	-	-	-	-	-	-
NADHPLIE_00263	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF1846)
NADHPLIE_00264	1.55e-240	pta	2.3.1.8	-	C	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphate acetyltransferase
NADHPLIE_00265	7.92e-208	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NADHPLIE_00266	0.0	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NADHPLIE_00267	2.23e-49	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Peptidase family S51
NADHPLIE_00268	7.47e-172	-	-	-	L	-	-	-	Phage integrase family
NADHPLIE_00270	1.39e-278	-	-	-	-	-	-	-	-
NADHPLIE_00271	0.0	glgX	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
NADHPLIE_00272	1.45e-156	-	-	-	L	-	-	-	NUDIX domain
NADHPLIE_00273	4.35e-185	-	-	-	L	-	-	-	NIF3 (NGG1p interacting factor 3)
NADHPLIE_00274	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NADHPLIE_00275	4.78e-74	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NADHPLIE_00276	5.44e-161	pdtaR	-	-	T	ko:K22010	-	ko00000,ko00002,ko02022	Response regulator receiver domain protein
NADHPLIE_00278	8.13e-141	aspA	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
NADHPLIE_00279	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
NADHPLIE_00280	2.78e-228	terC	-	-	P	ko:K05794	-	ko00000	Integral membrane protein, TerC family
NADHPLIE_00281	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NADHPLIE_00282	2.24e-139	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NADHPLIE_00283	1.63e-276	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
NADHPLIE_00284	2.97e-211	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NADHPLIE_00285	1.55e-232	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
NADHPLIE_00286	6.96e-211	-	-	-	P	ko:K02074	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NADHPLIE_00287	2.15e-177	znuB	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
NADHPLIE_00288	2.62e-51	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NADHPLIE_00289	1.99e-131	carD	-	-	K	ko:K07736	-	ko00000,ko03000	CarD-like/TRCF domain
NADHPLIE_00290	1.08e-82	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NADHPLIE_00291	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NADHPLIE_00292	5.39e-163	cseB	-	-	T	-	-	-	Response regulator receiver domain protein
NADHPLIE_00293	2.41e-258	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NADHPLIE_00294	3.2e-93	umuD	-	-	KT	ko:K03503	-	ko00000,ko01000,ko01002,ko03400	Peptidase S24-like
NADHPLIE_00295	9.49e-165	pyrE_1	-	-	S	-	-	-	Phosphoribosyl transferase domain
NADHPLIE_00296	2.33e-200	-	-	-	T	-	-	-	Eukaryotic phosphomannomutase
NADHPLIE_00297	1.05e-85	-	-	-	S	-	-	-	Zincin-like metallopeptidase
NADHPLIE_00298	0.0	-	-	-	-	-	-	-	-
NADHPLIE_00299	0.0	-	-	-	S	-	-	-	Glycosyl transferase, family 2
NADHPLIE_00300	2.82e-72	whiB2	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
NADHPLIE_00301	0.0	lytR2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
NADHPLIE_00302	1.41e-235	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
NADHPLIE_00303	8.78e-133	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
NADHPLIE_00304	6.69e-61	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
NADHPLIE_00305	0.0	pdtaS	2.7.13.3	-	T	ko:K00936	-	ko00000,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NADHPLIE_00306	2.77e-193	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
NADHPLIE_00308	0.0	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NADHPLIE_00309	0.0	degP	-	-	O	ko:K08372	ko02020,map02020	ko00000,ko00001,ko01000,ko01002	Domain present in PSD-95, Dlg, and ZO-1/2.
NADHPLIE_00310	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
NADHPLIE_00311	0.0	fprA	1.18.1.2, 1.19.1.1	-	C	ko:K00528	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase
NADHPLIE_00312	4.06e-217	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
NADHPLIE_00315	8.39e-47	-	-	-	S	-	-	-	Protein of unknown function DUF262
NADHPLIE_00316	4.59e-99	-	-	-	S	-	-	-	Protein of unknown function DUF262
NADHPLIE_00317	3.01e-15	int8	-	-	L	-	-	-	Phage integrase family
NADHPLIE_00318	2.42e-246	-	-	-	-	-	-	-	-
NADHPLIE_00319	9.59e-104	-	-	-	S	-	-	-	Nucleotidyltransferase domain
NADHPLIE_00320	1.48e-88	-	-	-	K	-	-	-	FR47-like protein
NADHPLIE_00321	7.22e-54	-	-	-	S	-	-	-	Polyketide cyclase / dehydrase and lipid transport
NADHPLIE_00322	5.68e-106	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
NADHPLIE_00323	4.53e-45	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
NADHPLIE_00325	1.46e-78	-	-	-	-	-	-	-	-
NADHPLIE_00326	1.64e-315	-	3.2.1.8, 3.5.1.104	-	G	ko:K01181,ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
NADHPLIE_00327	1.25e-252	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
NADHPLIE_00328	2.16e-81	-	-	-	D	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
NADHPLIE_00330	9.71e-317	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NADHPLIE_00331	5.91e-209	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NADHPLIE_00332	3.43e-79	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NADHPLIE_00333	1.55e-253	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NADHPLIE_00334	7.39e-98	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Domain of unknown function (DUF1964)
NADHPLIE_00335	0.0	scrT	-	-	G	-	-	-	Transporter major facilitator family protein
NADHPLIE_00336	9.25e-260	-	-	-	EGP	-	-	-	Sugar (and other) transporter
NADHPLIE_00337	1.23e-50	-	-	-	EGP	-	-	-	Sugar (and other) transporter
NADHPLIE_00338	2.9e-145	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NADHPLIE_00339	3.34e-94	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NADHPLIE_00340	7.18e-260	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NADHPLIE_00341	9.44e-234	-	-	-	S	-	-	-	Protein of unknown function (DUF559)
NADHPLIE_00342	0.0	lacZ	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
NADHPLIE_00343	0.0	aroP	-	-	E	ko:K03293,ko:K11732	-	ko00000,ko02000	aromatic amino acid transport protein AroP K03293
NADHPLIE_00344	7.06e-132	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
NADHPLIE_00345	4.31e-166	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NADHPLIE_00346	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NADHPLIE_00347	2.21e-109	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NADHPLIE_00348	1.11e-149	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NADHPLIE_00349	1.09e-51	urtE	-	-	E	ko:K11963	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NADHPLIE_00350	1.95e-127	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Redoxin
NADHPLIE_00351	1.87e-192	-	-	-	S	ko:K07058	-	ko00000	Virulence factor BrkB
NADHPLIE_00352	8.66e-57	-	-	-	O	-	-	-	Glutaredoxin
NADHPLIE_00353	7.38e-138	-	-	-	L	ko:K07485	-	ko00000	Transposase
NADHPLIE_00354	0.0	-	-	-	S	-	-	-	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NADHPLIE_00355	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
NADHPLIE_00356	2.86e-72	-	-	-	L	ko:K07454	-	ko00000	HNH endonuclease
NADHPLIE_00357	5.43e-291	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
NADHPLIE_00358	4.12e-184	-	-	-	-	-	-	-	-
NADHPLIE_00359	5e-170	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NADHPLIE_00360	9.36e-165	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NADHPLIE_00361	1.57e-54	-	-	-	IQ	-	-	-	[acyl-carrier-protein] S-malonyltransferase activity
NADHPLIE_00362	3.51e-58	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
NADHPLIE_00363	3.77e-270	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
NADHPLIE_00364	0.0	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
NADHPLIE_00365	0.0	-	-	-	M	-	-	-	domain protein
NADHPLIE_00366	7.03e-70	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Acylphosphatase
NADHPLIE_00367	4.13e-189	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NADHPLIE_00368	5.54e-234	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NADHPLIE_00369	3.4e-113	-	-	-	M	-	-	-	Protein of unknown function (DUF3152)
NADHPLIE_00370	3.99e-176	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
NADHPLIE_00374	3.96e-89	-	-	-	E	-	-	-	Domain of unknown function (DUF5011)
NADHPLIE_00375	1.42e-37	-	-	-	S	-	-	-	Parallel beta-helix repeats
NADHPLIE_00377	1.35e-91	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
NADHPLIE_00378	1.51e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NADHPLIE_00379	7.91e-111	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
NADHPLIE_00380	6.47e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
NADHPLIE_00381	5.52e-241	-	-	-	T	-	-	-	Pfam Adenylate and Guanylate cyclase catalytic domain
NADHPLIE_00382	6.48e-164	-	-	-	-	-	-	-	-
NADHPLIE_00384	0.0	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NADHPLIE_00385	1.45e-46	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NADHPLIE_00386	3.98e-11	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NADHPLIE_00387	4.18e-152	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NADHPLIE_00388	1.73e-274	-	3.2.1.97	GH101	G	ko:K17624	-	ko00000,ko01000	Glycosyl hydrolase 101 beta sandwich domain
NADHPLIE_00389	0.0	-	3.2.1.97	GH101	G	ko:K17624	-	ko00000,ko01000	Glycosyl hydrolase 101 beta sandwich domain
NADHPLIE_00390	1.23e-252	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
NADHPLIE_00391	2.94e-227	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
NADHPLIE_00392	3.24e-226	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
NADHPLIE_00393	1.8e-221	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
NADHPLIE_00394	2.49e-161	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
NADHPLIE_00395	6.78e-42	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NADHPLIE_00397	1.95e-292	aspC	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
NADHPLIE_00398	2.13e-256	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NADHPLIE_00399	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NADHPLIE_00400	3.08e-226	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NADHPLIE_00401	2.12e-53	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
NADHPLIE_00402	1.44e-62	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
NADHPLIE_00403	0.0	rne	3.1.26.12	-	J	ko:K08300,ko:K08301	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	Ribonuclease E/G family
NADHPLIE_00405	4.92e-305	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
NADHPLIE_00406	1.27e-187	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
NADHPLIE_00407	0.0	-	-	-	V	-	-	-	Efflux ABC transporter, permease protein
NADHPLIE_00408	5.55e-211	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NADHPLIE_00409	2.73e-76	-	-	-	-	-	-	-	-
NADHPLIE_00410	1.4e-87	-	-	-	-	-	-	-	-
NADHPLIE_00411	0.0	maf	-	-	DF	ko:K06287	-	ko00000	Maf-like protein
NADHPLIE_00412	3.19e-238	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NADHPLIE_00413	4.09e-24	hom	1.1.1.3, 2.7.2.4	-	E	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
NADHPLIE_00414	3.66e-229	hom	1.1.1.3, 2.7.2.4	-	E	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
NADHPLIE_00415	1.24e-117	nagE	2.7.1.193	-	G	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
NADHPLIE_00416	6.4e-200	nagE	2.7.1.193	-	G	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
NADHPLIE_00417	5.94e-107	-	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NADHPLIE_00418	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NADHPLIE_00419	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
NADHPLIE_00420	7.92e-230	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
NADHPLIE_00421	2.69e-82	psp1	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	Endoribonuclease L-PSP
NADHPLIE_00422	1.78e-300	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
NADHPLIE_00423	9.44e-187	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NADHPLIE_00424	4.67e-165	-	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
NADHPLIE_00425	5.17e-56	-	-	-	-	-	-	-	-
NADHPLIE_00426	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
NADHPLIE_00427	7.77e-314	-	-	-	-	-	-	-	-
NADHPLIE_00428	4.11e-196	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NADHPLIE_00429	2.85e-285	sucC	6.2.1.5	-	F	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NADHPLIE_00430	3.9e-131	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NADHPLIE_00431	3.73e-72	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
NADHPLIE_00432	6.91e-259	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NADHPLIE_00433	1.83e-135	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NADHPLIE_00434	2.64e-129	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NADHPLIE_00435	2.79e-176	yebC	-	-	K	-	-	-	transcriptional regulatory protein
NADHPLIE_00436	2.81e-274	-	3.2.1.52	GH20	M	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
NADHPLIE_00437	0.0	-	3.2.1.52	GH20	M	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
NADHPLIE_00438	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NADHPLIE_00439	3.53e-106	-	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NADHPLIE_00440	5.62e-207	-	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NADHPLIE_00443	3.27e-274	-	-	-	-	-	-	-	-
NADHPLIE_00447	2.89e-199	-	-	-	S	-	-	-	PAC2 family
NADHPLIE_00448	8.18e-216	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NADHPLIE_00449	8.17e-204	-	-	-	G	-	-	-	Fructosamine kinase
NADHPLIE_00450	6.31e-273	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NADHPLIE_00451	2.42e-281	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NADHPLIE_00452	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
NADHPLIE_00453	4.49e-258	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NADHPLIE_00454	1.88e-183	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
NADHPLIE_00455	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
NADHPLIE_00457	4.27e-308	-	-	-	V	-	-	-	MatE
NADHPLIE_00458	3.47e-208	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NADHPLIE_00459	1.23e-227	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
NADHPLIE_00460	1.2e-45	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
NADHPLIE_00461	3.84e-189	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NADHPLIE_00462	3.43e-206	pgk	2.7.2.3, 5.3.1.1	-	F	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
NADHPLIE_00463	8.54e-34	pgk	2.7.2.3, 5.3.1.1	-	F	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
NADHPLIE_00464	1.39e-79	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
NADHPLIE_00466	1.63e-139	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
NADHPLIE_00467	6.12e-230	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate dehydrogenase substrate binding domain
NADHPLIE_00468	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NADHPLIE_00469	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NADHPLIE_00470	6.79e-119	-	-	-	-	-	-	-	-
NADHPLIE_00471	6.28e-77	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
NADHPLIE_00473	2.13e-151	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
NADHPLIE_00474	6.16e-315	-	2.7.13.3	-	T	ko:K18351	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NADHPLIE_00475	2.4e-180	-	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
NADHPLIE_00476	0.0	ybiT	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
NADHPLIE_00477	7.97e-252	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
NADHPLIE_00478	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
NADHPLIE_00479	1.64e-262	-	2.7.1.162	-	S	ko:K13059	-	ko00000,ko01000	Phosphotransferase enzyme family
NADHPLIE_00480	1.24e-257	-	-	-	GK	-	-	-	ROK family
NADHPLIE_00481	7.38e-203	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
NADHPLIE_00482	1.92e-306	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
NADHPLIE_00483	1.06e-83	-	-	-	E	-	-	-	Rard protein
NADHPLIE_00484	3.98e-228	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NADHPLIE_00485	4.92e-266	trmI	2.1.1.219, 2.1.1.220	-	J	ko:K07442	-	ko00000,ko01000,ko03016	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NADHPLIE_00486	8.29e-129	sixA	-	-	T	ko:K08296	-	ko00000,ko01000	Phosphoglycerate mutase family
NADHPLIE_00487	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NADHPLIE_00488	6.48e-14	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
NADHPLIE_00489	6.64e-154	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
NADHPLIE_00491	0.0	glnE	2.7.7.42, 2.7.7.89	-	H	ko:K00982	-	ko00000,ko01000	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
NADHPLIE_00492	2.71e-234	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
NADHPLIE_00493	1.83e-96	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
NADHPLIE_00494	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NADHPLIE_00495	3.28e-230	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
NADHPLIE_00496	7.23e-200	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
NADHPLIE_00497	7.1e-230	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NADHPLIE_00498	1.41e-103	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NADHPLIE_00499	6.28e-248	adh	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
NADHPLIE_00500	1.39e-27	-	-	-	-	-	-	-	-
NADHPLIE_00501	5.29e-150	-	-	-	-	-	-	-	-
NADHPLIE_00502	9.62e-18	-	-	-	KLT	-	-	-	Protein tyrosine kinase
NADHPLIE_00503	2.32e-16	-	-	-	KLT	-	-	-	Protein tyrosine kinase
NADHPLIE_00504	4.82e-96	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NADHPLIE_00505	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NADHPLIE_00506	3.85e-25	-	-	-	V	-	-	-	MatE
NADHPLIE_00507	1.76e-259	-	-	-	V	-	-	-	MatE
NADHPLIE_00508	4.85e-169	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
NADHPLIE_00509	1.02e-171	-	-	-	L	ko:K07457	-	ko00000	endonuclease III
NADHPLIE_00510	3.05e-121	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
NADHPLIE_00511	1.61e-226	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
NADHPLIE_00512	2.58e-89	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin domain
NADHPLIE_00513	3.85e-282	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	HipA N-terminal domain
NADHPLIE_00514	1.17e-54	-	-	-	K	-	-	-	Helix-turn-helix
NADHPLIE_00515	1.02e-64	tam	2.1.1.144, 2.1.1.197	-	FG	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	trans-aconitate 2-methyltransferase activity
NADHPLIE_00516	6.5e-25	-	-	-	-	-	-	-	-
NADHPLIE_00517	9.18e-92	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NADHPLIE_00518	3.22e-119	-	-	-	T	-	-	-	Domain of unknown function (DUF4234)
NADHPLIE_00519	1.23e-221	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
NADHPLIE_00520	3.89e-157	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
NADHPLIE_00521	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NADHPLIE_00522	7.48e-186	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
NADHPLIE_00523	3.58e-115	dkg	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
NADHPLIE_00525	0.0	ugp	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
NADHPLIE_00526	0.0	-	-	-	K	-	-	-	WYL domain
NADHPLIE_00527	2.14e-69	-	-	-	-	-	-	-	-
NADHPLIE_00528	0.0	helY	-	-	L	ko:K03727	-	ko00000,ko01000	DEAD DEAH box helicase
NADHPLIE_00529	1.11e-81	rbpA	-	-	K	-	-	-	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
NADHPLIE_00530	2.42e-182	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
NADHPLIE_00534	1.23e-116	-	-	-	K	-	-	-	Putative zinc ribbon domain
NADHPLIE_00535	4.36e-162	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
NADHPLIE_00536	8.43e-31	-	-	-	L	-	-	-	DNA integration
NADHPLIE_00538	8.13e-82	-	-	-	-	-	-	-	-
NADHPLIE_00539	2.29e-82	merR2	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NADHPLIE_00540	2.88e-96	garA	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
NADHPLIE_00541	7.92e-182	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
NADHPLIE_00542	2.78e-57	sbp	-	-	S	-	-	-	Protein of unknown function (DUF1290)
NADHPLIE_00543	2.59e-59	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
NADHPLIE_00544	3.49e-147	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
NADHPLIE_00545	2.22e-151	pgsA2	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NADHPLIE_00546	1.07e-200	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
NADHPLIE_00547	6.28e-37	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-ATP pyrophosphohydrolase
NADHPLIE_00549	8.92e-144	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3-epimerase
NADHPLIE_00550	1.23e-84	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NADHPLIE_00551	1.07e-111	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NADHPLIE_00552	1.31e-209	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NADHPLIE_00553	4.15e-274	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NADHPLIE_00554	6.38e-212	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NADHPLIE_00555	0.0	der	-	-	F	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
NADHPLIE_00556	6.29e-77	-	-	-	-	-	-	-	-
NADHPLIE_00557	3.42e-158	-	-	-	-	-	-	-	-
NADHPLIE_00558	9.05e-257	idsA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NADHPLIE_00559	7.16e-209	pknL	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	PASTA
NADHPLIE_00560	1.29e-232	pknL	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	PASTA
NADHPLIE_00561	1.45e-171	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
NADHPLIE_00562	4.56e-142	-	-	-	-	-	-	-	-
NADHPLIE_00563	4.38e-223	trpD	2.4.2.18	-	F	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NADHPLIE_00564	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NADHPLIE_00565	3.68e-152	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NADHPLIE_00567	9.83e-37	-	-	-	K	-	-	-	Winged helix DNA-binding domain
NADHPLIE_00568	5.65e-95	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
NADHPLIE_00569	4.46e-275	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NADHPLIE_00570	3.38e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF3046)
NADHPLIE_00571	2.53e-106	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NADHPLIE_00572	1.14e-124	cinA	3.5.1.42	-	S	ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
NADHPLIE_00573	6.37e-160	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NADHPLIE_00574	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE family protein
NADHPLIE_00575	3e-175	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
NADHPLIE_00576	2.03e-211	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NADHPLIE_00577	0.0	miaB	2.8.4.3	-	H	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NADHPLIE_00578	1.42e-156	ywaC	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
NADHPLIE_00579	1.59e-216	-	-	-	EG	-	-	-	EamA-like transporter family
NADHPLIE_00580	3.03e-27	-	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
NADHPLIE_00581	7.7e-131	-	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
NADHPLIE_00582	2.31e-147	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
NADHPLIE_00583	6.37e-89	-	-	-	T	-	-	-	Histidine kinase
NADHPLIE_00584	5.71e-220	-	-	-	T	-	-	-	Histidine kinase
NADHPLIE_00585	6.09e-152	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
NADHPLIE_00586	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
NADHPLIE_00587	0.0	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
NADHPLIE_00588	1.84e-183	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
NADHPLIE_00589	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
NADHPLIE_00590	1.4e-303	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
NADHPLIE_00591	5.84e-150	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NADHPLIE_00592	3.8e-135	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NADHPLIE_00594	1.56e-206	-	-	-	EGP	-	-	-	Transmembrane secretion effector
NADHPLIE_00595	0.0	-	-	-	S	-	-	-	Esterase-like activity of phytase
NADHPLIE_00596	5.83e-293	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NADHPLIE_00597	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NADHPLIE_00598	9.4e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NADHPLIE_00599	5.77e-81	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NADHPLIE_00601	1.33e-255	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
NADHPLIE_00602	2.1e-289	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
NADHPLIE_00603	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
NADHPLIE_00604	2e-142	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NADHPLIE_00605	1.48e-271	fucO	1.1.1.77, 1.1.99.37, 1.2.98.1	-	C	ko:K00048,ko:K17067	ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
NADHPLIE_00606	2.58e-225	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NADHPLIE_00607	1.54e-182	-	-	-	S	-	-	-	AI-2E family transporter
NADHPLIE_00608	3.29e-138	-	-	-	S	-	-	-	AI-2E family transporter
NADHPLIE_00609	3.97e-295	-	-	-	M	-	-	-	Glycosyl transferase family 21
NADHPLIE_00610	2.26e-215	natA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NADHPLIE_00611	0.0	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
NADHPLIE_00612	0.0	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-Ala-D-Ala carboxypeptidase 3 (S13) family
NADHPLIE_00613	1.42e-50	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NADHPLIE_00614	2.15e-201	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NADHPLIE_00615	2.65e-127	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
NADHPLIE_00616	6.46e-47	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NADHPLIE_00617	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NADHPLIE_00618	2.05e-130	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
NADHPLIE_00619	1.03e-25	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NADHPLIE_00620	1.98e-112	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NADHPLIE_00621	7.44e-289	folK	2.7.6.3, 4.1.2.25	-	H	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NADHPLIE_00622	1.99e-63	folK	2.7.6.3, 4.1.2.25	-	H	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NADHPLIE_00623	3.06e-103	-	-	-	S	-	-	-	Protein of unknown function (DUF3180)
NADHPLIE_00624	7.02e-140	tesB	-	-	I	ko:K10805	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	Thioesterase-like superfamily
NADHPLIE_00626	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	hydrolase family 20, catalytic
NADHPLIE_00627	0.0	yjjK	-	-	S	-	-	-	ATP-binding cassette protein, ChvD family
NADHPLIE_00628	8.64e-24	-	-	-	M	-	-	-	domain, Protein
NADHPLIE_00629	1.37e-56	-	-	-	M	-	-	-	domain, Protein
NADHPLIE_00630	4.33e-162	-	-	-	-	-	-	-	-
NADHPLIE_00632	8.2e-23	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NADHPLIE_00633	1.57e-105	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NADHPLIE_00634	1.74e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
NADHPLIE_00635	3.61e-65	-	-	-	S	-	-	-	DUF218 domain
NADHPLIE_00637	4.04e-149	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
NADHPLIE_00638	1.77e-165	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NADHPLIE_00639	4.9e-76	-	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	Major facilitator Superfamily
NADHPLIE_00640	0.0	-	-	-	S	-	-	-	ATPases associated with a variety of cellular activities
NADHPLIE_00641	3.68e-229	glkA	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
NADHPLIE_00642	8.66e-16	-	-	-	EGP	-	-	-	Major facilitator superfamily
NADHPLIE_00643	4.99e-66	-	-	-	EGP	-	-	-	Major facilitator superfamily
NADHPLIE_00644	5.34e-46	-	-	-	C	-	-	-	Aldo/keto reductase family
NADHPLIE_00645	0.0	-	2.5.1.49	-	H	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.98
NADHPLIE_00646	1.17e-267	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
NADHPLIE_00647	6.46e-37	-	-	-	L	-	-	-	Transposase
NADHPLIE_00649	2.03e-191	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
NADHPLIE_00650	3.7e-189	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NADHPLIE_00651	2.85e-05	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NADHPLIE_00652	1.23e-210	-	-	-	EG	-	-	-	EamA-like transporter family
NADHPLIE_00653	0.0	-	-	-	JKL	-	-	-	helicase superfamily c-terminal domain
NADHPLIE_00654	3.95e-189	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
NADHPLIE_00655	9.63e-63	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
NADHPLIE_00656	5.32e-121	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
NADHPLIE_00657	4.84e-101	-	-	-	-	-	-	-	-
NADHPLIE_00658	0.0	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	Mycolic acid cyclopropane synthetase
NADHPLIE_00659	4.72e-240	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
NADHPLIE_00660	4.54e-208	-	-	-	G	ko:K05340	-	ko00000,ko02000	Sugar transport protein
NADHPLIE_00661	8.53e-32	-	-	-	E	-	-	-	Rard protein
NADHPLIE_00662	5.4e-39	-	-	-	-	-	-	-	-
NADHPLIE_00663	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
NADHPLIE_00664	0.0	-	-	-	S	ko:K06915	-	ko00000	AAA-like domain
NADHPLIE_00665	1.99e-68	-	-	-	S	-	-	-	SIR2-like domain
NADHPLIE_00666	6.12e-233	-	-	-	V	-	-	-	Type III restriction enzyme res subunit
NADHPLIE_00667	1.65e-70	-	-	-	L	-	-	-	Eco57I restriction-modification methylase
NADHPLIE_00668	1.79e-48	-	-	-	L	-	-	-	Eco57I restriction-modification methylase
NADHPLIE_00669	0.0	-	-	-	KL	-	-	-	Type III restriction enzyme res subunit
NADHPLIE_00670	8.33e-30	-	-	-	-	-	-	-	-
NADHPLIE_00671	3.82e-39	-	-	-	-	-	-	-	-
NADHPLIE_00672	1.35e-38	-	-	-	-	ko:K07485	-	ko00000	-
NADHPLIE_00673	1.3e-229	-	-	-	L	ko:K07485	-	ko00000	Transposase
NADHPLIE_00674	1.32e-51	-	-	-	L	-	-	-	Helix-turn-helix domain
NADHPLIE_00675	1.3e-238	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NADHPLIE_00676	4.91e-67	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
NADHPLIE_00677	2.67e-166	-	-	-	S	ko:K11206	-	ko00000,ko01000	Carbon-nitrogen hydrolase
NADHPLIE_00678	3.9e-38	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NADHPLIE_00679	5.67e-121	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NADHPLIE_00680	2.88e-313	glgA	2.4.1.342	GT4	G	ko:K16148	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Starch synthase catalytic domain
NADHPLIE_00681	5.23e-107	-	-	-	-	-	-	-	-
NADHPLIE_00682	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
NADHPLIE_00683	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase NADPH large subunit
NADHPLIE_00684	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
NADHPLIE_00685	0.0	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K10907,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase, class I II
NADHPLIE_00686	3.3e-312	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
NADHPLIE_00687	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NADHPLIE_00688	3.91e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
NADHPLIE_00689	4.63e-175	-	-	-	S	-	-	-	UPF0126 domain
NADHPLIE_00690	3.48e-36	-	-	-	T	-	-	-	RNA ligase
NADHPLIE_00691	1.65e-61	-	-	-	S	-	-	-	phosphoesterase or phosphohydrolase
NADHPLIE_00692	1.58e-287	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Amino-transferase class IV
NADHPLIE_00693	1.66e-128	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NADHPLIE_00694	2.09e-242	-	-	-	S	ko:K06889	-	ko00000	alpha beta
NADHPLIE_00695	1.72e-306	pntB	1.6.1.2	-	C	ko:K00325	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
NADHPLIE_00696	1.08e-58	pntAB	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	4TM region of pyridine nucleotide transhydrogenase, mitoch
NADHPLIE_00697	6.9e-259	pntA	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	NAD(P) transhydrogenase subunit alpha part 1 K00324
NADHPLIE_00698	0.0	fadD2	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
NADHPLIE_00699	8.32e-225	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NADHPLIE_00700	0.0	corC	-	-	S	-	-	-	CBS domain
NADHPLIE_00701	1.82e-130	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NADHPLIE_00702	2.32e-166	phoH	-	-	T	ko:K06217	-	ko00000	PhoH-like protein
NADHPLIE_00703	1.37e-76	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
NADHPLIE_00704	1.53e-106	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NADHPLIE_00706	1.78e-208	spoU2	-	-	J	-	-	-	SpoU rRNA Methylase family
NADHPLIE_00707	1.42e-308	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NADHPLIE_00708	2.56e-141	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
NADHPLIE_00709	4.14e-132	iscU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
NADHPLIE_00710	2.55e-306	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NADHPLIE_00711	2.13e-185	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
NADHPLIE_00712	8.37e-298	sufD	-	-	O	ko:K09015	-	ko00000	FeS assembly protein SufD
NADHPLIE_00713	0.0	sufB	-	-	O	ko:K09014	-	ko00000	FeS assembly protein SufB
NADHPLIE_00714	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NADHPLIE_00715	1.76e-05	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase (surface protein transpeptidase)
NADHPLIE_00716	3.46e-154	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
NADHPLIE_00717	2.14e-21	-	-	-	-	-	-	-	-
NADHPLIE_00718	1.87e-102	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
NADHPLIE_00719	6.14e-233	aroB	2.7.1.71, 4.2.3.4	-	H	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NADHPLIE_00720	1.33e-145	aroB	2.7.1.71, 4.2.3.4	-	H	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NADHPLIE_00721	4.5e-280	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NADHPLIE_00722	5.3e-69	-	3.4.23.43	-	S	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
NADHPLIE_00723	4.48e-247	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NADHPLIE_00724	6.58e-99	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NADHPLIE_00725	1.1e-46	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NADHPLIE_00726	2.83e-151	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NADHPLIE_00727	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NADHPLIE_00728	7.33e-50	-	-	-	-	-	-	-	-
NADHPLIE_00729	4.37e-173	-	5.4.2.12	-	G	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
NADHPLIE_00730	0.0	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
NADHPLIE_00731	1.83e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NADHPLIE_00732	2.83e-174	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NADHPLIE_00733	7.96e-273	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NADHPLIE_00734	2.46e-84	-	-	-	S	-	-	-	Domain of unknown function (DUF4418)
NADHPLIE_00735	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
NADHPLIE_00738	0.0	yrhL	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
NADHPLIE_00739	6.52e-139	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NADHPLIE_00740	7.11e-309	pbuX	-	-	F	ko:K03458	-	ko00000	Permease family
NADHPLIE_00742	8.63e-56	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NADHPLIE_00743	1.22e-50	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NADHPLIE_00745	5.11e-146	pncA	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Isochorismatase family
NADHPLIE_00746	1.13e-53	-	-	-	-	-	-	-	-
NADHPLIE_00747	5.74e-34	-	-	-	S	-	-	-	Adenine-specific methyltransferase EcoRI
NADHPLIE_00748	1.12e-140	-	-	-	-	-	-	-	-
NADHPLIE_00750	1.67e-104	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NADHPLIE_00751	7.02e-94	fkbP	5.2.1.8	-	G	ko:K01802	-	ko00000,ko01000	Peptidyl-prolyl cis-trans
NADHPLIE_00752	0.0	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
NADHPLIE_00753	1.26e-125	-	-	-	-	-	-	-	-
NADHPLIE_00755	1.06e-213	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
NADHPLIE_00756	2.85e-28	-	-	-	S	ko:K09009	-	ko00000	Protein of unknown function (DUF501)
NADHPLIE_00757	6.12e-99	-	-	-	S	ko:K09009	-	ko00000	Protein of unknown function (DUF501)
NADHPLIE_00758	5.95e-131	-	-	-	D	-	-	-	Septum formation initiator
NADHPLIE_00759	7.41e-315	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NADHPLIE_00760	9.33e-16	pabC	2.6.1.42, 2.6.1.85, 4.1.3.38	-	E	ko:K00826,ko:K01665,ko:K02619,ko:K03342	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	branched-chain-amino-acid transaminase activity
NADHPLIE_00761	6.89e-163	pabC	2.6.1.42, 2.6.1.85, 4.1.3.38	-	E	ko:K00826,ko:K01665,ko:K02619,ko:K03342	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	branched-chain-amino-acid transaminase activity
NADHPLIE_00762	0.0	pabB	2.6.1.85, 4.1.3.27, 4.1.3.38	-	EH	ko:K01657,ko:K01665,ko:K03342,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000,ko01007	chorismate binding enzyme
NADHPLIE_00763	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NADHPLIE_00764	1.79e-88	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NADHPLIE_00765	2.98e-40	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NADHPLIE_00766	3.71e-126	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
NADHPLIE_00767	1.97e-186	rfbB2	3.6.3.40	-	GM	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NADHPLIE_00768	1.2e-194	-	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
NADHPLIE_00769	2.01e-251	-	-	-	GM	-	-	-	GDP-mannose 4,6 dehydratase
NADHPLIE_00770	2.12e-164	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NADHPLIE_00773	9.06e-256	-	-	-	I	ko:K13663	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
NADHPLIE_00774	0.0	-	2.7.8.14, 2.7.8.47	-	M	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NADHPLIE_00775	9.7e-262	-	2.7.8.14, 2.7.8.47	-	M	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NADHPLIE_00776	1.03e-165	-	-	-	S	ko:K09118	-	ko00000	Uncharacterised protein family (UPF0182)
NADHPLIE_00777	2.19e-259	-	-	-	S	ko:K09118	-	ko00000	Uncharacterised protein family (UPF0182)
NADHPLIE_00778	3.92e-226	-	-	-	S	ko:K09118	-	ko00000	Uncharacterised protein family (UPF0182)
NADHPLIE_00779	2.22e-294	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
NADHPLIE_00780	2.19e-250	-	-	-	-	-	-	-	-
NADHPLIE_00781	2.49e-187	-	-	-	V	ko:K02003,ko:K09810	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NADHPLIE_00782	2.87e-218	-	-	-	V	-	-	-	N-Acetylmuramoyl-L-alanine amidase
NADHPLIE_00783	2.3e-13	-	-	-	V	-	-	-	N-Acetylmuramoyl-L-alanine amidase
NADHPLIE_00784	8.18e-29	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
NADHPLIE_00785	1.85e-60	argE	-	-	E	-	-	-	Peptidase dimerisation domain
NADHPLIE_00786	3.34e-253	argE	-	-	E	-	-	-	Peptidase dimerisation domain
NADHPLIE_00787	5.94e-134	-	-	-	S	-	-	-	Protein of unknown function (DUF3043)
NADHPLIE_00788	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NADHPLIE_00789	7.09e-181	-	-	-	S	-	-	-	Domain of unknown function (DUF4191)
NADHPLIE_00790	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
NADHPLIE_00794	1.5e-15	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
NADHPLIE_00798	1.9e-98	-	-	-	S	-	-	-	GIY-YIG catalytic domain
NADHPLIE_00799	2.5e-39	-	3.1.21.4	-	L	ko:K01155	-	ko00000,ko01000,ko02048	Recognizes the double-stranded sequence CTCGAG and cleaves after C-1
NADHPLIE_00800	2.69e-137	-	-	-	L	-	-	-	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NADHPLIE_00801	7.24e-106	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
NADHPLIE_00802	7.06e-204	-	-	-	S	-	-	-	Protein conserved in bacteria
NADHPLIE_00803	3.21e-266	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NADHPLIE_00804	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NADHPLIE_00805	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
NADHPLIE_00806	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NADHPLIE_00807	1.9e-53	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NADHPLIE_00808	3.99e-44	-	2.8.2.22	-	S	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
NADHPLIE_00809	5.17e-177	-	-	-	P	ko:K16784	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NADHPLIE_00810	3.37e-270	-	-	-	E	-	-	-	Aminotransferase class I and II
NADHPLIE_00811	2.21e-178	ppgK	2.7.1.2, 2.7.1.63	-	GK	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
NADHPLIE_00812	4.85e-136	-	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NADHPLIE_00813	0.0	-	-	-	GP	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NADHPLIE_00814	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NADHPLIE_00816	0.0	rarA	-	-	L	ko:K07478	-	ko00000	Recombination factor protein RarA
NADHPLIE_00817	0.0	-	-	-	L	-	-	-	DEAD DEAH box helicase
NADHPLIE_00818	2.49e-255	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
NADHPLIE_00819	1.56e-245	gluD	-	-	E	ko:K10007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NADHPLIE_00820	2.97e-144	gluC	-	-	E	ko:K10006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NADHPLIE_00821	2.4e-195	gluB	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
NADHPLIE_00822	2.08e-180	gluA	-	-	E	ko:K10008	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding protein of ABC transporter for glutamate K02028
NADHPLIE_00823	3.75e-119	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
NADHPLIE_00824	4.02e-108	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
NADHPLIE_00825	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NADHPLIE_00826	9.41e-239	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
NADHPLIE_00827	5.26e-302	-	-	-	S	-	-	-	Domain of Unknown Function (DUF349)
NADHPLIE_00830	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
NADHPLIE_00831	6.2e-240	uspA	-	-	T	-	-	-	Belongs to the universal stress protein A family
NADHPLIE_00832	1.28e-252	-	-	-	S	-	-	-	Protein of unknown function (DUF3027)
NADHPLIE_00833	1.23e-87	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
NADHPLIE_00834	0.0	phoR	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NADHPLIE_00835	1.23e-171	phoP	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulator receiver domain protein
NADHPLIE_00836	5.35e-236	-	-	-	-	-	-	-	-
NADHPLIE_00837	8.25e-53	-	-	-	S	-	-	-	Proteins of 100 residues with WXG
NADHPLIE_00838	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NADHPLIE_00839	2.97e-41	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
NADHPLIE_00840	1.05e-16	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
NADHPLIE_00841	9.88e-63	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
NADHPLIE_00842	8.58e-185	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NADHPLIE_00843	7.38e-253	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
NADHPLIE_00844	1.19e-230	-	-	-	S	-	-	-	Protein of unknown function DUF58
NADHPLIE_00845	1.07e-122	-	-	-	-	-	-	-	-
NADHPLIE_00846	7.9e-247	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
NADHPLIE_00847	6.68e-197	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
NADHPLIE_00848	2.65e-115	-	-	-	-	-	-	-	-
NADHPLIE_00850	1.4e-168	-	-	-	S	-	-	-	PGAP1-like protein
NADHPLIE_00851	8.84e-140	-	-	-	S	-	-	-	PGAP1-like protein
NADHPLIE_00852	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminal
NADHPLIE_00853	1.73e-86	-	-	-	S	-	-	-	Lysylphosphatidylglycerol synthase TM region
NADHPLIE_00854	0.0	-	-	-	S	-	-	-	Lysylphosphatidylglycerol synthase TM region
NADHPLIE_00855	4.7e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
NADHPLIE_00856	0.0	pafA	6.3.1.19	-	O	ko:K13571	-	ko00000,ko00002,ko01000,ko03051	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NADHPLIE_00857	1.05e-28	pup	-	-	S	ko:K13570	-	ko00000,ko04121	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
NADHPLIE_00858	3.75e-207	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
NADHPLIE_00859	0.0	dop	3.5.1.119	-	S	ko:K20814	-	ko00000,ko01000,ko03051	Pup-ligase protein
NADHPLIE_00860	0.0	arc	-	-	O	ko:K13527	ko03050,map03050	ko00000,ko00001,ko00002,ko03051	AAA ATPase forming ring-shaped complexes
NADHPLIE_00861	2.25e-178	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
NADHPLIE_00862	1.29e-233	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NADHPLIE_00863	3.86e-174	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
NADHPLIE_00864	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NADHPLIE_00865	3.81e-137	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NADHPLIE_00866	7.86e-285	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NADHPLIE_00867	9.87e-70	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NADHPLIE_00868	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
NADHPLIE_00869	2.81e-42	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
NADHPLIE_00870	2.59e-212	-	-	-	S	-	-	-	Protein conserved in bacteria
NADHPLIE_00872	2.26e-64	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NADHPLIE_00873	1.02e-171	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NADHPLIE_00874	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NADHPLIE_00875	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
NADHPLIE_00876	2.27e-10	-	-	-	-	-	-	-	-
NADHPLIE_00877	2.45e-61	-	-	-	-	-	-	-	-
NADHPLIE_00878	2.21e-181	nfrA	-	-	C	-	-	-	Nitroreductase family
NADHPLIE_00879	9.49e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF4235)
NADHPLIE_00880	1.02e-171	gpm2	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
NADHPLIE_00881	6.15e-06	-	-	-	M	-	-	-	cell wall anchor domain protein
NADHPLIE_00883	7.54e-241	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NADHPLIE_00884	0.0	strK	3.1.3.1, 3.1.3.39	-	P	ko:K01077,ko:K04342	ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
NADHPLIE_00885	3.14e-37	strK	3.1.3.1, 3.1.3.39	-	P	ko:K01077,ko:K04342	ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
NADHPLIE_00886	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
NADHPLIE_00887	3.29e-80	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NADHPLIE_00888	2.72e-236	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	DnaJ molecular chaperone homology domain
NADHPLIE_00889	6.42e-112	hspR	-	-	K	ko:K13640	-	ko00000,ko03000	transcriptional regulator, MerR family
NADHPLIE_00890	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR repeat-like domain
NADHPLIE_00891	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR Asp-box repeat
NADHPLIE_00892	0.0	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NADHPLIE_00893	5.83e-178	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
NADHPLIE_00895	2.18e-162	dedA1	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
NADHPLIE_00896	7.65e-220	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NADHPLIE_00897	1.6e-83	-	-	-	-	-	-	-	-
NADHPLIE_00898	5.41e-170	-	-	-	-	-	-	-	-
NADHPLIE_00899	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NADHPLIE_00900	1.72e-110	-	-	-	K	-	-	-	Transcriptional regulator
NADHPLIE_00901	2.11e-09	-	-	-	G	ko:K02027,ko:K10188	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NADHPLIE_00902	2.58e-66	-	-	-	G	ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
NADHPLIE_00903	3.12e-24	-	-	-	G	ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
NADHPLIE_00904	9.6e-18	-	-	-	G	ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
NADHPLIE_00905	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
NADHPLIE_00906	2.36e-222	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
NADHPLIE_00907	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
NADHPLIE_00908	0.0	pepX	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Dipeptidyl peptidase IV (DPP IV) N-terminal region
NADHPLIE_00909	3.69e-167	fhaA	-	-	T	-	-	-	Protein of unknown function (DUF2662)
NADHPLIE_00910	1.44e-122	fhaB	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
NADHPLIE_00911	2.31e-295	pstP	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
NADHPLIE_00912	5.71e-34	pstP	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
NADHPLIE_00913	0.0	rodA	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
NADHPLIE_00914	0.0	pbpA	-	-	M	ko:K05364	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
NADHPLIE_00915	1.2e-196	pknA	2.7.11.1	-	T	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
NADHPLIE_00916	0.0	pknB	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
NADHPLIE_00917	5.06e-131	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	para-aminobenzoate synthase glutamine amidotransferase component II
NADHPLIE_00918	5.65e-296	srtB	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
NADHPLIE_00919	2.39e-182	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
NADHPLIE_00920	8.05e-100	crgA	-	-	D	-	-	-	Involved in cell division
NADHPLIE_00921	0.0	-	-	-	L	-	-	-	ribosomal rna small subunit methyltransferase
NADHPLIE_00922	9.1e-160	-	-	-	L	-	-	-	HTH-like domain
NADHPLIE_00923	2.4e-186	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
NADHPLIE_00924	7.68e-47	-	-	-	-	-	-	-	-
NADHPLIE_00926	2.97e-190	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NADHPLIE_00928	5.53e-96	-	-	-	I	-	-	-	Sterol carrier protein
NADHPLIE_00929	2.33e-99	-	-	-	V	ko:K06147	-	ko00000,ko02000	ATPases associated with a variety of cellular activities
NADHPLIE_00930	1.01e-56	istB	-	-	L	-	-	-	IstB-like ATP binding protein
NADHPLIE_00931	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
NADHPLIE_00932	7.74e-17	-	-	-	-	-	-	-	-
NADHPLIE_00933	2.28e-77	yccF	-	-	S	-	-	-	Inner membrane component domain
NADHPLIE_00934	2.14e-280	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
NADHPLIE_00935	4.71e-57	-	-	-	-	-	-	-	-
NADHPLIE_00936	2.68e-32	-	-	-	-	-	-	-	-
NADHPLIE_00937	2.82e-308	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NADHPLIE_00938	1.87e-172	-	-	-	S	-	-	-	Protein of unknown function (DUF3159)
NADHPLIE_00939	2.66e-196	-	-	-	S	-	-	-	Protein of unknown function (DUF3710)
NADHPLIE_00940	1.66e-214	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
NADHPLIE_00941	0.0	-	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
NADHPLIE_00942	2.49e-276	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
NADHPLIE_00943	4.24e-35	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
NADHPLIE_00944	0.0	oppD	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NADHPLIE_00945	1.06e-101	oppD	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NADHPLIE_00946	5.29e-212	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
NADHPLIE_00947	4.8e-226	oppB1	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NADHPLIE_00948	4.74e-236	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
NADHPLIE_00949	2.67e-56	-	-	-	-	-	-	-	-
NADHPLIE_00950	2.98e-245	tyrA	1.3.1.12	-	E	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
NADHPLIE_00951	2.67e-249	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
NADHPLIE_00952	1.57e-110	-	-	-	-	-	-	-	-
NADHPLIE_00953	0.0	typA	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
NADHPLIE_00954	1.22e-71	typA	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
NADHPLIE_00955	1.52e-299	iscS1	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
NADHPLIE_00956	3.33e-211	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
NADHPLIE_00957	0.0	nadB	1.4.3.16, 2.4.2.19	-	H	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
NADHPLIE_00958	0.0	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NADHPLIE_00959	5.17e-192	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX hydrolase
NADHPLIE_00960	1.74e-144	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NADHPLIE_00961	6.85e-193	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NADHPLIE_00962	1.31e-194	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
NADHPLIE_00963	9.73e-228	xerD	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	recombinase XerD
NADHPLIE_00964	5.46e-81	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NADHPLIE_00965	3.31e-35	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
NADHPLIE_00966	5.1e-146	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NADHPLIE_00967	2.33e-09	-	-	-	S	-	-	-	Spermine/spermidine synthase domain
NADHPLIE_00968	6.42e-11	-	-	-	S	-	-	-	Spermine/spermidine synthase domain
NADHPLIE_00969	3.98e-171	-	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamin pyrophosphokinase, vitamin B1 binding domain
NADHPLIE_00970	3.39e-254	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NADHPLIE_00971	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NADHPLIE_00972	6.24e-228	-	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
NADHPLIE_00973	9.8e-251	-	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
NADHPLIE_00974	2e-71	-	-	-	K	-	-	-	MerR, DNA binding
NADHPLIE_00975	7.76e-69	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
NADHPLIE_00976	5.12e-51	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
NADHPLIE_00977	2.92e-131	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease, DNA polymerase III, epsilon subunit family
NADHPLIE_00978	0.0	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
NADHPLIE_00979	1.25e-191	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
NADHPLIE_00980	5.53e-109	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
NADHPLIE_00981	6.86e-10	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
NADHPLIE_00982	0.0	pepO	3.4.24.11, 3.4.24.71	-	O	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase family M13
NADHPLIE_00983	5.41e-73	ssb2	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
NADHPLIE_00984	2.2e-218	-	-	-	-	-	-	-	-
NADHPLIE_00985	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NADHPLIE_00988	1.7e-73	-	-	-	L	-	-	-	PIF1-like helicase
NADHPLIE_00989	5.69e-251	-	-	-	L	-	-	-	PIF1-like helicase
NADHPLIE_00990	5.74e-205	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NADHPLIE_00991	1.11e-155	orn	-	-	L	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NADHPLIE_00992	1.11e-48	-	-	-	KT	ko:K02483	-	ko00000,ko02022	Transcriptional regulatory protein, C terminal
NADHPLIE_00993	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
NADHPLIE_00994	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NADHPLIE_00995	1.5e-260	rfe	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 4
NADHPLIE_00996	1.15e-54	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
NADHPLIE_00997	7.76e-33	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
NADHPLIE_00998	2.18e-19	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
NADHPLIE_00999	4.51e-79	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Bacterial transferase hexapeptide repeat protein
NADHPLIE_01000	1.91e-31	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NADHPLIE_01001	5.34e-178	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NADHPLIE_01002	1.17e-246	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NADHPLIE_01003	1.85e-48	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
NADHPLIE_01005	4.61e-250	-	-	-	K	ko:K13633	-	ko00000,ko03000	helix_turn_helix, arabinose operon control protein
NADHPLIE_01006	7.25e-240	pdxB	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NADHPLIE_01007	6.12e-197	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
NADHPLIE_01008	4.43e-180	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	oligopeptide transport protein of the ABC superfamily, ATP-binding component
NADHPLIE_01009	4.5e-211	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NADHPLIE_01010	6.98e-218	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NADHPLIE_01011	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
NADHPLIE_01012	2.65e-184	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NADHPLIE_01013	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NADHPLIE_01014	6.83e-76	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	carbohydrate transport
NADHPLIE_01015	2.88e-203	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
NADHPLIE_01016	3.13e-311	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
NADHPLIE_01017	1.68e-132	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
NADHPLIE_01018	4.38e-243	-	-	-	K	-	-	-	Periplasmic binding protein domain
NADHPLIE_01019	9.41e-15	-	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
NADHPLIE_01020	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
NADHPLIE_01022	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NADHPLIE_01023	4.8e-73	-	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
NADHPLIE_01024	0.0	aldH	1.2.1.3, 1.2.99.10	-	C	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldehyde dehydrogenase family
NADHPLIE_01025	5.07e-178	hflK	-	-	O	-	-	-	prohibitin homologues
NADHPLIE_01026	6.06e-309	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
NADHPLIE_01027	1.69e-297	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
NADHPLIE_01028	0.0	nox	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
NADHPLIE_01029	3.12e-180	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
NADHPLIE_01031	1.51e-259	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NADHPLIE_01032	2.17e-120	tsnR	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NADHPLIE_01033	3.67e-56	-	-	-	V	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NADHPLIE_01034	3.13e-103	-	-	-	V	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NADHPLIE_01035	2.65e-175	-	-	-	V	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
NADHPLIE_01036	8.71e-61	-	-	-	IQ	-	-	-	oxidoreductase activity
NADHPLIE_01038	5.16e-103	-	-	-	K	-	-	-	AraC-like ligand binding domain
NADHPLIE_01039	1.12e-303	rutG	-	-	F	ko:K02824,ko:K03458	-	ko00000,ko02000	Permease family
NADHPLIE_01040	6.99e-204	-	-	-	G	-	-	-	Phosphoglycerate mutase family
NADHPLIE_01041	4.96e-72	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
NADHPLIE_01042	5.54e-239	-	-	-	S	-	-	-	Conserved hypothetical protein 698
NADHPLIE_01043	6.07e-185	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
NADHPLIE_01044	5.02e-55	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
NADHPLIE_01045	1.08e-72	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
NADHPLIE_01046	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NADHPLIE_01048	0.0	-	2.7.11.1	-	S	ko:K12132	-	ko00000,ko01000,ko01001	PASTA domain
NADHPLIE_01049	2.6e-161	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
NADHPLIE_01050	1.5e-96	fms	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
NADHPLIE_01051	1.59e-48	-	-	-	-	-	-	-	-
NADHPLIE_01052	2.36e-46	-	-	-	S	ko:K07069	-	ko00000	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
NADHPLIE_01053	7.03e-86	-	-	-	S	-	-	-	Zincin-like metallopeptidase
NADHPLIE_01054	1.1e-112	-	-	-	S	-	-	-	Helix-turn-helix
NADHPLIE_01055	1.6e-260	-	-	-	S	-	-	-	Short C-terminal domain
NADHPLIE_01056	3.84e-31	-	-	-	-	-	-	-	-
NADHPLIE_01057	2.07e-233	-	-	-	-	-	-	-	-
NADHPLIE_01059	6.04e-103	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NADHPLIE_01060	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
NADHPLIE_01061	2.2e-103	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
NADHPLIE_01062	1.56e-201	-	-	-	J	-	-	-	Methyltransferase domain
NADHPLIE_01063	5.59e-78	yccF	-	-	S	-	-	-	Inner membrane component domain
NADHPLIE_01064	3.88e-162	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
NADHPLIE_01065	7.23e-124	-	-	-	F	-	-	-	NUDIX domain
NADHPLIE_01066	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
NADHPLIE_01067	0.0	-	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NADHPLIE_01068	2.16e-248	dppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NADHPLIE_01069	5.3e-243	dppB	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NADHPLIE_01070	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
NADHPLIE_01071	2.49e-58	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
NADHPLIE_01072	3.73e-59	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
NADHPLIE_01074	5.93e-196	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NADHPLIE_01075	5.86e-276	-	-	-	GK	-	-	-	ROK family
NADHPLIE_01076	1.39e-168	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
NADHPLIE_01077	5.33e-286	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
NADHPLIE_01078	2.87e-217	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
NADHPLIE_01079	5.3e-301	-	-	-	G	-	-	-	Major Facilitator Superfamily
NADHPLIE_01080	7.59e-109	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NADHPLIE_01083	4.13e-232	ftsQ	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
NADHPLIE_01084	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
NADHPLIE_01085	2.58e-275	murG	2.4.1.227, 6.3.2.8	GT28	M	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NADHPLIE_01086	3.69e-296	ftsW	2.4.1.227	GT28	D	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	Belongs to the SEDS family
NADHPLIE_01087	2.23e-182	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NADHPLIE_01089	8.76e-261	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NADHPLIE_01090	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NADHPLIE_01091	2.89e-230	-	-	-	M	-	-	-	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NADHPLIE_01092	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding protein, transpeptidase domain protein
NADHPLIE_01093	2.38e-41	-	-	-	D	-	-	-	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NADHPLIE_01094	3.57e-87	yogA	-	-	C	-	-	-	Zinc-binding dehydrogenase
NADHPLIE_01095	5.14e-111	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NADHPLIE_01096	1.72e-289	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NADHPLIE_01097	1.95e-94	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
NADHPLIE_01098	1.27e-59	-	-	-	-	-	-	-	-
NADHPLIE_01099	6.18e-196	-	-	-	S	-	-	-	TIGRFAM TIGR03943 family protein
NADHPLIE_01100	1.61e-254	-	-	-	S	ko:K07089	-	ko00000	Predicted permease
NADHPLIE_01101	1.07e-32	-	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal L32p protein family
NADHPLIE_01102	1.03e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L36
NADHPLIE_01103	4.38e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
NADHPLIE_01104	4.85e-65	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NADHPLIE_01105	4.39e-62	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
NADHPLIE_01106	1.07e-41	-	-	-	S	-	-	-	cobalamin synthesis protein
NADHPLIE_01107	1.02e-96	-	-	-	S	-	-	-	cobalamin synthesis protein
NADHPLIE_01108	2.61e-206	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
NADHPLIE_01110	0.0	lysX	-	-	S	-	-	-	Uncharacterised conserved protein (DUF2156)
NADHPLIE_01111	0.0	-	-	-	S	-	-	-	Putative esterase
NADHPLIE_01112	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
NADHPLIE_01113	1.41e-157	purD	6.3.3.1, 6.3.4.13	-	F	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
NADHPLIE_01114	1.14e-130	purD	6.3.3.1, 6.3.4.13	-	F	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
NADHPLIE_01115	1.21e-244	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
NADHPLIE_01116	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NADHPLIE_01117	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	DNA-damage repair protein (DNA polymerase IV) K00961
NADHPLIE_01118	2.24e-41	-	-	-	-	-	-	-	-
NADHPLIE_01119	8.12e-91	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NADHPLIE_01120	5.05e-22	-	-	-	K	-	-	-	DNA-binding transcription factor activity
NADHPLIE_01121	3.62e-149	nnrE	-	-	L	-	-	-	Uracil DNA glycosylase superfamily
NADHPLIE_01122	2.46e-137	-	-	-	S	-	-	-	Protein of unknown function (DUF4230)
NADHPLIE_01123	1.5e-138	-	-	-	-	-	-	-	-
NADHPLIE_01124	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
NADHPLIE_01125	7.47e-119	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
NADHPLIE_01126	8e-177	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
NADHPLIE_01127	2.23e-145	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NADHPLIE_01128	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NADHPLIE_01129	7.85e-290	-	-	-	L	-	-	-	Transposase and inactivated derivatives
NADHPLIE_01130	6.48e-179	ltbR	-	-	K	-	-	-	Transcriptional regulator, IclR family, C-terminal domain protein
NADHPLIE_01131	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NADHPLIE_01132	9.49e-171	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NADHPLIE_01133	0.0	-	-	-	KL	-	-	-	Psort location Cytoplasmic, score 8.87
NADHPLIE_01135	7.89e-248	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NADHPLIE_01136	5.26e-281	pyr	1.3.98.1	-	F	ko:K00226	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
NADHPLIE_01137	0.0	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NADHPLIE_01138	1.66e-289	-	-	-	G	-	-	-	Transmembrane secretion effector
NADHPLIE_01139	1.39e-168	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NADHPLIE_01140	1.36e-180	-	-	-	-	-	-	-	-
NADHPLIE_01141	1.43e-95	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NADHPLIE_01142	1.23e-159	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NADHPLIE_01143	5.14e-222	-	5.2.1.8	-	M	ko:K01802	-	ko00000,ko01000	FKBP-type peptidyl-prolyl cis-trans isomerase
NADHPLIE_01144	2.08e-242	-	-	-	-	-	-	-	-
NADHPLIE_01145	4.83e-231	-	-	-	-	-	-	-	-
NADHPLIE_01146	2.07e-213	ybbN	-	-	O	ko:K05838	-	ko00000,ko03110	Tetratricopeptide repeat
NADHPLIE_01147	4.54e-151	-	-	-	S	-	-	-	CYTH
NADHPLIE_01150	1.98e-235	-	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
NADHPLIE_01151	1.3e-71	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
NADHPLIE_01152	2.85e-207	-	1.1.1.100, 1.1.1.413	-	IQ	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
NADHPLIE_01156	3.19e-214	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
NADHPLIE_01157	4.28e-86	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NADHPLIE_01159	1.5e-311	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NADHPLIE_01160	0.0	trpE	4.1.3.27	-	E	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NADHPLIE_01161	3.8e-96	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NADHPLIE_01162	1.82e-179	hisF	4.1.3.27	-	E	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NADHPLIE_01163	3.97e-103	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NADHPLIE_01164	9.53e-162	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NADHPLIE_01165	1.27e-226	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
NADHPLIE_01166	7.62e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NADHPLIE_01167	2.44e-146	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
NADHPLIE_01168	3.84e-165	-	-	-	S	-	-	-	alpha beta
NADHPLIE_01169	4.78e-188	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NADHPLIE_01170	3.07e-188	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
NADHPLIE_01171	4.26e-113	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NADHPLIE_01172	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	long-chain-fatty acid CoA ligase
NADHPLIE_01173	3.59e-118	-	-	-	-	-	-	-	-
NADHPLIE_01174	1.59e-255	guaB3	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase family protein
NADHPLIE_01175	5.51e-306	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
NADHPLIE_01176	0.0	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
NADHPLIE_01177	0.0	fadD1	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
NADHPLIE_01178	1.18e-161	-	-	-	M	-	-	-	Peptidase family M23
NADHPLIE_01180	1.61e-250	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NADHPLIE_01181	4.95e-134	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	FR47-like protein
NADHPLIE_01182	2.92e-128	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Glycoprotease family
NADHPLIE_01183	7.81e-44	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Glycoprotease family
NADHPLIE_01184	9.66e-142	tsaE	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
NADHPLIE_01185	4.22e-228	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
NADHPLIE_01186	1.57e-179	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
NADHPLIE_01187	4.17e-186	cobB2	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
NADHPLIE_01188	4.42e-295	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
NADHPLIE_01189	1.12e-109	tadA	3.5.4.1, 3.5.4.33	-	FJ	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NADHPLIE_01190	3.83e-184	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
NADHPLIE_01191	0.0	nhaP	-	-	P	ko:K03316	-	ko00000	Sodium/hydrogen exchanger family
NADHPLIE_01192	6.04e-144	dcd	3.5.4.13	-	F	ko:K01494	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dCTP deaminase family
NADHPLIE_01193	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
NADHPLIE_01194	0.0	pacL2	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
NADHPLIE_01196	2.98e-221	rlmB	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NADHPLIE_01197	0.0	-	-	-	KLT	-	-	-	Domain of unknown function (DUF4032)
NADHPLIE_01198	6.12e-197	-	-	-	-	-	-	-	-
NADHPLIE_01199	3.19e-137	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
NADHPLIE_01200	2.68e-287	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
NADHPLIE_01201	0.0	-	-	-	S	-	-	-	LPXTG-motif cell wall anchor domain protein
NADHPLIE_01202	1.89e-133	-	-	-	L	-	-	-	Helix-turn-helix domain
NADHPLIE_01203	8.07e-253	ugpC	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NADHPLIE_01204	1.54e-220	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NADHPLIE_01205	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
NADHPLIE_01206	1.5e-200	-	-	-	O	-	-	-	Thioredoxin
NADHPLIE_01208	9.75e-280	rpfB	-	-	S	ko:K21688	-	ko00000	G5
NADHPLIE_01209	8.92e-218	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NADHPLIE_01210	4.91e-143	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NADHPLIE_01211	6.94e-146	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
NADHPLIE_01212	0.0	pcnA	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Probable RNA and SrmB- binding site of polymerase A
NADHPLIE_01213	3.18e-160	mutT4	-	-	L	-	-	-	Belongs to the Nudix hydrolase family
NADHPLIE_01214	0.0	-	-	-	M	-	-	-	Conserved repeat domain
NADHPLIE_01215	0.0	mviN	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
NADHPLIE_01216	1.72e-234	mviN	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
NADHPLIE_01217	3.87e-231	mviN	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
NADHPLIE_01218	4.58e-257	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NADHPLIE_01219	5.19e-308	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NADHPLIE_01220	1.01e-227	parA	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
NADHPLIE_01221	1.5e-161	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
NADHPLIE_01222	4.15e-120	jag	-	-	S	ko:K06346	-	ko00000	Putative single-stranded nucleic acids-binding domain
NADHPLIE_01223	1e-225	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
NADHPLIE_01224	3.88e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
NADHPLIE_01225	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NADHPLIE_01226	1.15e-259	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NADHPLIE_01227	4.66e-296	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NADHPLIE_01228	1.36e-125	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
NADHPLIE_01229	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NADHPLIE_01230	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NADHPLIE_01231	2.04e-104	-	-	-	S	-	-	-	Transmembrane domain of unknown function (DUF3566)
NADHPLIE_01234	1.24e-239	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
NADHPLIE_01235	7.64e-239	-	-	-	K	-	-	-	Periplasmic binding protein domain
NADHPLIE_01236	1.02e-247	-	-	-	I	-	-	-	Serine aminopeptidase, S33
NADHPLIE_01237	9.05e-12	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NADHPLIE_01238	2.87e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF2442)
NADHPLIE_01239	2.73e-19	-	-	-	S	-	-	-	Domain of unknown function (DUF4160)
NADHPLIE_01240	3.02e-20	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NADHPLIE_01242	9.2e-08	-	-	-	M	-	-	-	PA domain
NADHPLIE_01243	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
NADHPLIE_01244	6.61e-124	gntR	-	-	K	-	-	-	FCD
NADHPLIE_01245	9.15e-79	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NADHPLIE_01246	2.27e-254	-	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	arabinose metabolic process
NADHPLIE_01247	0.0	-	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	arabinose metabolic process
NADHPLIE_01251	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
NADHPLIE_01253	3.61e-244	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NADHPLIE_01254	2.54e-101	ulaC	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NADHPLIE_01255	1.49e-54	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NADHPLIE_01256	0.0	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
NADHPLIE_01257	8.13e-173	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
NADHPLIE_01258	2.68e-110	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
NADHPLIE_01259	4.01e-240	-	-	-	EG	-	-	-	EamA-like transporter family
NADHPLIE_01260	3.36e-306	-	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
NADHPLIE_01261	1.2e-113	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NADHPLIE_01262	2.03e-152	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
NADHPLIE_01263	1.01e-137	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
NADHPLIE_01264	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
NADHPLIE_01265	3.18e-95	-	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
NADHPLIE_01266	2.34e-194	-	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
NADHPLIE_01267	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NADHPLIE_01268	0.0	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
NADHPLIE_01269	2.19e-227	-	-	-	S	-	-	-	Amidohydrolase family
NADHPLIE_01270	1.01e-73	-	-	-	S	-	-	-	Protein conserved in bacteria
NADHPLIE_01271	5.3e-153	-	-	-	S	-	-	-	Protein conserved in bacteria
NADHPLIE_01272	3.44e-261	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NADHPLIE_01273	5.42e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF3073)
NADHPLIE_01274	1.48e-74	-	-	-	K	-	-	-	LytTr DNA-binding domain
NADHPLIE_01275	5.95e-97	-	-	-	T	-	-	-	protein histidine kinase activity
NADHPLIE_01276	1.24e-260	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NADHPLIE_01277	1.92e-37	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
NADHPLIE_01278	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
NADHPLIE_01279	1.67e-220	-	-	-	M	-	-	-	Glycosyl transferase family 2
NADHPLIE_01280	0.0	-	-	-	-	-	-	-	-
NADHPLIE_01281	3.19e-127	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NADHPLIE_01282	0.0	rfbD	1.1.1.133, 5.1.3.13	-	M	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NADHPLIE_01283	6.72e-209	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NADHPLIE_01284	2e-88	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NADHPLIE_01285	9.39e-135	tagG	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
NADHPLIE_01286	1.85e-204	-	-	-	GM	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NADHPLIE_01287	0.0	-	-	-	M	ko:K07272	-	ko00000,ko01000,ko01003,ko01005	Rhamnan synthesis protein F
NADHPLIE_01288	4.4e-246	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NADHPLIE_01289	1.11e-268	ugd	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP binding domain
NADHPLIE_01290	6.68e-21	-	-	-	L	-	-	-	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NADHPLIE_01291	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
NADHPLIE_01292	8.26e-199	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NADHPLIE_01293	4.7e-143	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NADHPLIE_01296	6.91e-220	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
NADHPLIE_01297	2.44e-130	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
NADHPLIE_01298	4.4e-256	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
NADHPLIE_01299	5.8e-16	-	-	-	E	-	-	-	Domain of unknown function (DUF5011)
NADHPLIE_01300	5.17e-218	-	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
NADHPLIE_01301	4.2e-149	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
NADHPLIE_01302	1.45e-297	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
NADHPLIE_01303	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
NADHPLIE_01304	2.78e-177	rfbP	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
NADHPLIE_01305	2.14e-119	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NADHPLIE_01306	2.6e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF4127)
NADHPLIE_01307	1.65e-72	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
NADHPLIE_01308	3.23e-108	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NADHPLIE_01311	1.29e-108	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	DNA topoisomerase
NADHPLIE_01312	1.71e-116	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	DNA topoisomerase
NADHPLIE_01315	6.03e-86	-	-	-	-	-	-	-	-
NADHPLIE_01316	1.74e-75	-	-	-	S	-	-	-	pathogenesis
NADHPLIE_01317	2.86e-48	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
NADHPLIE_01318	5.6e-205	-	-	-	L	ko:K07493	-	ko00000	PFAM Transposase, Mutator family
NADHPLIE_01319	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NADHPLIE_01320	1.45e-125	-	-	-	S	-	-	-	GtrA-like protein
NADHPLIE_01321	9.48e-83	-	-	-	S	-	-	-	Macrophage migration inhibitory factor (MIF)
NADHPLIE_01322	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate-tetrahydrofolate ligase
NADHPLIE_01323	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
NADHPLIE_01324	3.03e-139	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
NADHPLIE_01325	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
NADHPLIE_01327	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
NADHPLIE_01328	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NADHPLIE_01329	7.47e-123	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NADHPLIE_01330	6.3e-244	-	-	-	C	-	-	-	Aldo/keto reductase family
NADHPLIE_01331	0.000314	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 30 family
NADHPLIE_01332	3.03e-69	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 30 family
NADHPLIE_01333	9.64e-31	-	-	-	-	-	-	-	-
NADHPLIE_01335	2.79e-118	-	-	-	Q	-	-	-	4'-phosphopantetheinyl transferase superfamily
NADHPLIE_01336	1.11e-148	-	-	-	K	-	-	-	WHG domain
NADHPLIE_01337	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NADHPLIE_01339	9.88e-58	-	-	-	S	ko:K06990	-	ko00000,ko04812	Memo-like protein
NADHPLIE_01340	1.04e-289	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
NADHPLIE_01341	1.84e-204	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
NADHPLIE_01342	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NADHPLIE_01343	3.14e-313	dgt	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
NADHPLIE_01344	0.0	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NADHPLIE_01345	0.0	aap1	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
NADHPLIE_01346	3.86e-129	cysE	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NADHPLIE_01347	6.54e-38	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NADHPLIE_01348	1.27e-118	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NADHPLIE_01349	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
NADHPLIE_01350	2.83e-282	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
NADHPLIE_01351	7.14e-242	cbs	2.5.1.47, 4.2.1.22	-	E	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
NADHPLIE_01352	1.03e-141	-	-	-	-	-	-	-	-
NADHPLIE_01353	1.83e-128	ybaK	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NADHPLIE_01354	1.13e-231	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NADHPLIE_01355	7.58e-248	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
NADHPLIE_01356	3.35e-84	-	-	-	-	-	-	-	-
NADHPLIE_01357	6.49e-164	sigH	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NADHPLIE_01358	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NADHPLIE_01359	2.97e-243	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
NADHPLIE_01360	1.55e-226	-	2.6.1.33	-	M	ko:K20429	-	ko00000,ko01000	DegT/DnrJ/EryC1/StrS aminotransferase family
NADHPLIE_01361	9.94e-42	-	2.6.1.33	-	M	ko:K20429	-	ko00000,ko01000	DegT/DnrJ/EryC1/StrS aminotransferase family
NADHPLIE_01362	4.4e-310	-	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp
NADHPLIE_01363	1.18e-128	-	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
NADHPLIE_01364	5.29e-18	-	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
NADHPLIE_01365	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
NADHPLIE_01366	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
NADHPLIE_01369	2.6e-37	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 28 family
NADHPLIE_01370	1.28e-156	-	-	-	-	-	-	-	-
NADHPLIE_01371	2.9e-296	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
NADHPLIE_01372	1.17e-307	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
NADHPLIE_01373	8.74e-153	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NADHPLIE_01374	6.99e-168	-	-	-	M	-	-	-	Mechanosensitive ion channel
NADHPLIE_01375	2.27e-93	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NADHPLIE_01376	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NADHPLIE_01377	1.2e-200	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
NADHPLIE_01378	2.92e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF4854)
NADHPLIE_01380	2.72e-111	-	-	-	Q	-	-	-	Acetyltransferase (GNAT) domain
NADHPLIE_01381	3.87e-200	-	-	-	I	-	-	-	Serine aminopeptidase, S33
NADHPLIE_01382	3.02e-70	-	-	-	S	-	-	-	Putative heavy-metal-binding
NADHPLIE_01384	1.23e-56	-	-	-	D	-	-	-	DivIVA domain protein
NADHPLIE_01385	1.3e-116	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
NADHPLIE_01386	0.0	-	-	-	KL	-	-	-	Domain of unknown function (DUF3427)
NADHPLIE_01387	6.71e-150	-	-	-	KL	-	-	-	Domain of unknown function (DUF3427)
NADHPLIE_01389	4.98e-252	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NADHPLIE_01391	1.35e-146	-	-	-	-	-	-	-	-
NADHPLIE_01392	7.96e-217	-	-	-	EG	-	-	-	EamA-like transporter family
NADHPLIE_01393	2.14e-261	pldB	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Serine aminopeptidase, S33
NADHPLIE_01394	0.0	lacZ6	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
NADHPLIE_01395	2.36e-91	lacZ6	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
NADHPLIE_01396	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
NADHPLIE_01397	7.77e-24	-	-	-	S	ko:K18955	-	ko00000,ko03000	Transcription factor WhiB
NADHPLIE_01399	3.95e-222	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NADHPLIE_01400	4.62e-254	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
NADHPLIE_01401	4.71e-102	-	-	-	S	-	-	-	Domain of unknown function (DUF4190)
NADHPLIE_01406	1.31e-107	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
NADHPLIE_01407	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NADHPLIE_01409	3.19e-155	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
NADHPLIE_01410	8.37e-257	-	-	-	P	-	-	-	NMT1/THI5 like
NADHPLIE_01411	4.1e-178	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
NADHPLIE_01412	1e-80	-	-	-	-	-	-	-	-
NADHPLIE_01413	2.97e-83	-	-	-	-	-	-	-	-
NADHPLIE_01414	0.0	-	-	-	-	-	-	-	-
NADHPLIE_01416	2.09e-61	-	-	-	K	-	-	-	cell envelope-related transcriptional attenuator
NADHPLIE_01417	1.43e-53	-	-	-	K	-	-	-	cell envelope-related transcriptional attenuator
NADHPLIE_01418	6.65e-18	-	-	-	L	-	-	-	Transposase
NADHPLIE_01419	1.98e-64	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
NADHPLIE_01420	2.26e-314	-	-	-	L	-	-	-	Transposase
NADHPLIE_01421	9.32e-176	-	-	-	L	-	-	-	IstB-like ATP binding protein
NADHPLIE_01423	5.87e-256	-	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
NADHPLIE_01424	1.47e-56	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NADHPLIE_01425	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NADHPLIE_01426	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
NADHPLIE_01427	5.91e-179	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NADHPLIE_01429	0.0	hgdC	-	-	I	-	-	-	CoA enzyme activase uncharacterised domain (DUF2229)
NADHPLIE_01430	0.0	hgdC	-	-	I	-	-	-	CoA enzyme activase uncharacterised domain (DUF2229)
NADHPLIE_01431	3.9e-213	-	-	-	-	-	-	-	-
NADHPLIE_01432	3.34e-82	egtA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Glutamate-cysteine ligase family 2(GCS2)
NADHPLIE_01433	9.81e-24	egtA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Glutamate-cysteine ligase family 2(GCS2)
NADHPLIE_01434	2.79e-178	egtA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Glutamate-cysteine ligase family 2(GCS2)
NADHPLIE_01435	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
NADHPLIE_01436	1.67e-113	-	-	-	K	-	-	-	MarR family
NADHPLIE_01437	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NADHPLIE_01438	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
NADHPLIE_01439	7.07e-180	-	-	-	S	-	-	-	Patatin-like phospholipase
NADHPLIE_01440	1.84e-194	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
NADHPLIE_01441	3.81e-201	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
NADHPLIE_01442	4.82e-147	-	-	-	S	-	-	-	Vitamin K epoxide reductase
NADHPLIE_01443	1.04e-212	PPA1328	3.1.3.97, 3.1.4.57	-	S	ko:K07053,ko:K20859	ko00440,map00440	ko00000,ko00001,ko01000	DNA polymerase alpha chain like domain
NADHPLIE_01444	9.31e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF3107)
NADHPLIE_01445	0.0	mphA	-	-	S	-	-	-	Aminoglycoside phosphotransferase
NADHPLIE_01446	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
NADHPLIE_01447	0.0	-	-	-	S	-	-	-	Zincin-like metallopeptidase
NADHPLIE_01448	8.84e-168	sdrC	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
NADHPLIE_01449	2.24e-86	-	-	-	S	-	-	-	Protein of unknown function (DUF3052)
NADHPLIE_01450	1.96e-248	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NADHPLIE_01451	1.52e-81	-	-	-	S	-	-	-	Thiamine-binding protein
NADHPLIE_01452	2.08e-210	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NADHPLIE_01453	3.43e-291	-	-	-	O	ko:K13525	ko04141,ko05134,map04141,map05134	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	AAA domain (Cdc48 subfamily)
NADHPLIE_01454	3.18e-72	-	-	-	-	-	-	-	-
NADHPLIE_01455	1.73e-26	-	-	-	-	-	-	-	-
NADHPLIE_01456	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NADHPLIE_01457	6.29e-85	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NADHPLIE_01458	4.31e-44	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NADHPLIE_01459	2.8e-42	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NADHPLIE_01460	5.55e-149	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NADHPLIE_01461	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Domain of unknown function (DUF4982)
NADHPLIE_01462	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Domain of unknown function (DUF4982)
NADHPLIE_01463	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
NADHPLIE_01464	2.77e-314	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NADHPLIE_01465	7.36e-194	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NADHPLIE_01466	2.6e-59	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NADHPLIE_01467	9.4e-105	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NADHPLIE_01468	1.35e-56	-	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
NADHPLIE_01469	9.24e-66	-	-	-	V	-	-	-	DivIVA protein
NADHPLIE_01470	5.06e-91	-	-	-	V	-	-	-	DivIVA protein
NADHPLIE_01471	4.6e-148	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NADHPLIE_01472	2.3e-226	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NADHPLIE_01474	1.25e-82	-	-	-	-	-	-	-	-
NADHPLIE_01475	2.62e-220	dapD	2.3.1.117	-	E	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
NADHPLIE_01476	2.07e-18	-	-	-	-	-	-	-	-
NADHPLIE_01477	5.51e-263	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NADHPLIE_01478	1.56e-150	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Cell division ATP-binding protein FtsE
NADHPLIE_01479	1.75e-202	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in cellular division
NADHPLIE_01480	1.68e-281	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain protein
NADHPLIE_01481	1.38e-103	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NADHPLIE_01482	2.2e-183	-	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	RNA pseudouridylate synthase
NADHPLIE_01484	2.17e-115	-	-	-	-	-	-	-	-
NADHPLIE_01485	9.38e-13	-	-	-	-	-	-	-	-
NADHPLIE_01486	3.79e-16	-	-	-	L	-	-	-	PFAM Integrase catalytic
NADHPLIE_01488	6.06e-308	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
NADHPLIE_01489	8.41e-280	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NADHPLIE_01490	4.85e-299	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NADHPLIE_01491	0.0	-	-	-	I	-	-	-	acetylesterase activity
NADHPLIE_01492	2.05e-182	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
NADHPLIE_01493	1.03e-197	uppS	2.5.1.31, 2.5.1.86, 2.5.1.88	-	H	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NADHPLIE_01494	3.9e-244	-	-	-	S	-	-	-	Domain of unknown function (DUF1963)
NADHPLIE_01495	1.09e-22	fosC	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
NADHPLIE_01496	1.58e-51	cscA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
NADHPLIE_01497	2.38e-86	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
NADHPLIE_01498	3.56e-247	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
NADHPLIE_01499	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
NADHPLIE_01500	4.68e-109	-	-	-	S	-	-	-	zinc-ribbon domain
NADHPLIE_01501	1.9e-62	-	-	-	J	ko:K07574	-	ko00000,ko03009	CRS1_YhbY
NADHPLIE_01502	1.77e-99	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
NADHPLIE_01503	7.95e-270	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
NADHPLIE_01504	5e-05	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NADHPLIE_01506	2.5e-258	-	-	-	K	-	-	-	WYL domain
NADHPLIE_01507	1.35e-199	-	-	-	S	-	-	-	Aldo/keto reductase family
NADHPLIE_01508	7.17e-221	dkgV	-	-	C	-	-	-	Aldo/keto reductase family
NADHPLIE_01509	3.42e-97	-	-	-	S	-	-	-	Domain of unknown function (DUF4186)
NADHPLIE_01511	8.01e-234	-	-	-	S	-	-	-	Protein conserved in bacteria
NADHPLIE_01512	0.0	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NADHPLIE_01513	1.46e-282	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NADHPLIE_01514	1.08e-145	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
NADHPLIE_01515	5.26e-102	-	-	-	-	-	-	-	-
NADHPLIE_01516	4.12e-36	-	-	-	-	-	-	-	-
NADHPLIE_01517	8.32e-168	hisA	5.3.1.16, 5.3.1.24	-	E	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
NADHPLIE_01518	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2252)
NADHPLIE_01519	0.0	glnA2	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
NADHPLIE_01520	5.82e-225	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
NADHPLIE_01521	1.22e-38	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
NADHPLIE_01522	3.31e-74	-	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major facilitator Superfamily
NADHPLIE_01523	1.64e-239	-	-	-	M	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
NADHPLIE_01524	0.0	hrpA	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Helicase associated domain (HA2) Add an annotation
NADHPLIE_01525	0.0	hrpA	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Helicase associated domain (HA2) Add an annotation
NADHPLIE_01526	2.51e-157	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
NADHPLIE_01527	5.78e-216	-	-	-	-	-	-	-	-
NADHPLIE_01528	5.11e-226	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NADHPLIE_01529	1.96e-226	ldh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NADHPLIE_01530	8.43e-91	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NADHPLIE_01531	4.62e-104	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NADHPLIE_01532	3.03e-166	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NADHPLIE_01533	2.4e-65	-	-	-	M	-	-	-	Lysin motif
NADHPLIE_01534	1.79e-107	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NADHPLIE_01535	3.93e-291	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
NADHPLIE_01536	0.0	-	-	-	L	-	-	-	DNA helicase
NADHPLIE_01537	8.85e-118	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
NADHPLIE_01538	1.22e-231	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NADHPLIE_01540	6.24e-125	-	-	-	-	-	-	-	-
NADHPLIE_01541	7.23e-85	-	-	-	D	-	-	-	MobA/MobL family
NADHPLIE_01542	3.33e-203	-	2.7.1.95	-	F	ko:K00897	-	ko00000,ko01000,ko01504	Phosphotransferase enzyme family
NADHPLIE_01545	8.04e-60	-	-	-	-	-	-	-	-
NADHPLIE_01547	1.49e-62	-	-	-	L	ko:K07483	-	ko00000	Transposase
NADHPLIE_01548	1.11e-161	-	-	-	G	-	-	-	Phosphoglycerate mutase family
NADHPLIE_01549	1.16e-241	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
NADHPLIE_01550	1.09e-225	-	-	-	-	-	-	-	-
NADHPLIE_01551	4.63e-34	tnp3503b	-	-	L	-	-	-	Transposase and inactivated derivatives
NADHPLIE_01552	2.31e-35	-	-	-	-	-	-	-	-
NADHPLIE_01554	9.14e-198	-	-	-	E	-	-	-	Transglutaminase/protease-like homologues
NADHPLIE_01555	0.0	gcs2	-	-	S	ko:K06048	-	ko00000,ko01000	A circularly permuted ATPgrasp
NADHPLIE_01556	1.86e-154	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NADHPLIE_01557	2.24e-41	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NADHPLIE_01558	1.26e-290	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	hydrolase family 20, catalytic
NADHPLIE_01559	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	hydrolase family 20, catalytic
NADHPLIE_01560	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	hydrolase family 20, catalytic
NADHPLIE_01561	2.74e-89	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
NADHPLIE_01562	1.4e-236	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NADHPLIE_01563	7.34e-86	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NADHPLIE_01564	6.96e-83	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NADHPLIE_01565	1.03e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
NADHPLIE_01566	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NADHPLIE_01567	4.79e-129	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NADHPLIE_01568	0.0	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NADHPLIE_01569	8.75e-94	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
NADHPLIE_01570	1.46e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30p/L7e
NADHPLIE_01571	2.04e-149	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NADHPLIE_01572	1.53e-76	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NADHPLIE_01573	2.69e-122	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NADHPLIE_01574	9.65e-91	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NADHPLIE_01575	7.06e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NADHPLIE_01576	1.6e-133	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NADHPLIE_01577	9.32e-70	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NADHPLIE_01578	8.58e-38	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NADHPLIE_01579	9.4e-57	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NADHPLIE_01580	6.77e-51	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
NADHPLIE_01581	2.71e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NADHPLIE_01582	4e-159	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NADHPLIE_01583	1.4e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NADHPLIE_01584	1.15e-196	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NADHPLIE_01585	2.54e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NADHPLIE_01586	1.34e-154	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
NADHPLIE_01587	6.65e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NADHPLIE_01588	5.42e-67	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
NADHPLIE_01589	3.91e-121	-	-	-	S	-	-	-	YwiC-like protein
NADHPLIE_01590	1.62e-205	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
NADHPLIE_01591	0.0	adhE	1.1.1.1, 1.2.1.10, 1.2.1.81	-	C	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
NADHPLIE_01592	3.5e-97	adhE	1.1.1.1, 1.2.1.10, 1.2.1.81	-	C	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
NADHPLIE_01593	1.99e-221	-	-	-	GK	-	-	-	transcriptional repressor of nag (N-acetylglucosamine) operon K02565
NADHPLIE_01594	0.0	glgX	3.2.1.196, 3.2.1.68	CBM48,GH13	G	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
NADHPLIE_01595	6.59e-77	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
NADHPLIE_01596	2.64e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NADHPLIE_01597	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
NADHPLIE_01598	1.7e-154	-	-	-	-	-	-	-	-
NADHPLIE_01599	5.69e-147	yigZ	-	-	S	-	-	-	Uncharacterized protein family UPF0029
NADHPLIE_01600	0.0	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
NADHPLIE_01602	1.81e-304	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NADHPLIE_01603	2.41e-131	dapC	-	-	E	-	-	-	Aminotransferase class I and II
NADHPLIE_01604	1.72e-140	dapC	-	-	E	-	-	-	Aminotransferase class I and II
NADHPLIE_01605	3.55e-81	fdxA	-	-	C	ko:K05524	-	ko00000	4Fe-4S binding domain
NADHPLIE_01606	4.5e-279	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
NADHPLIE_01607	2.71e-35	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
NADHPLIE_01611	7.73e-37	-	-	-	KLT	-	-	-	Associated with various cellular activities
NADHPLIE_01612	3.75e-165	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
NADHPLIE_01613	3.49e-63	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NADHPLIE_01614	1.01e-78	-	-	-	-	-	-	-	-
NADHPLIE_01615	2.17e-158	-	-	-	-	-	-	-	-
NADHPLIE_01616	1.2e-191	rimJ	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
NADHPLIE_01617	2.82e-154	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
NADHPLIE_01618	1.88e-51	-	-	-	S	-	-	-	Putative regulatory protein
NADHPLIE_01619	3.49e-140	-	-	-	NO	-	-	-	SAF
NADHPLIE_01620	2.87e-56	-	-	-	-	-	-	-	-
NADHPLIE_01621	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
NADHPLIE_01622	0.0	-	-	-	T	-	-	-	Forkhead associated domain
NADHPLIE_01624	5.13e-61	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NADHPLIE_01625	5.06e-115	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NADHPLIE_01626	9.85e-233	xynB2	1.1.1.169	-	E	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	lipolytic protein G-D-S-L family
NADHPLIE_01627	0.0	-	-	-	G	-	-	-	BNR repeat-like domain
NADHPLIE_01628	3.53e-169	-	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
NADHPLIE_01629	1.98e-101	-	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
NADHPLIE_01630	3.81e-184	-	-	-	S	-	-	-	Protein conserved in bacteria
NADHPLIE_01631	5.31e-159	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NADHPLIE_01632	2.21e-232	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
NADHPLIE_01633	8.51e-219	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
NADHPLIE_01634	4.49e-258	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import
NADHPLIE_01635	7.72e-165	regX3	-	-	KT	ko:K07776	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
NADHPLIE_01636	3.37e-307	phoR	2.7.13.3	-	T	ko:K07636,ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
NADHPLIE_01637	6.31e-160	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NADHPLIE_01638	3.6e-305	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NADHPLIE_01639	9.49e-136	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
NADHPLIE_01640	3.01e-54	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NADHPLIE_01641	8.41e-237	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NADHPLIE_01642	1.14e-276	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NADHPLIE_01643	1.27e-72	-	-	-	L	-	-	-	Excalibur calcium-binding domain
NADHPLIE_01645	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	elongation factor G
NADHPLIE_01646	1.33e-139	-	-	-	L	-	-	-	Excalibur calcium-binding domain
NADHPLIE_01647	1e-115	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
NADHPLIE_01648	1.88e-151	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
NADHPLIE_01649	1.15e-115	-	-	-	D	-	-	-	nuclear chromosome segregation
NADHPLIE_01650	3.17e-164	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NADHPLIE_01651	1.06e-184	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NADHPLIE_01652	5.52e-241	yfiH	-	-	Q	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
NADHPLIE_01653	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32 C-terminal domain
NADHPLIE_01654	2.45e-122	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
NADHPLIE_01655	2.86e-101	-	-	-	C	-	-	-	Oxidoreductase, aldo keto reductase family protein
NADHPLIE_01656	1.41e-75	-	-	-	C	-	-	-	Oxidoreductase, aldo keto reductase family protein
NADHPLIE_01657	1.26e-55	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
NADHPLIE_01658	2.53e-95	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
NADHPLIE_01659	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NADHPLIE_01660	7.28e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NADHPLIE_01661	6.87e-92	megL	4.4.1.11	-	E	ko:K01761	ko00270,ko00450,map00270,map00450	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
NADHPLIE_01662	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
NADHPLIE_01663	8.8e-120	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
NADHPLIE_01664	3.32e-145	xylR	-	-	K	ko:K02529	-	ko00000,ko03000	purine nucleotide biosynthetic process
NADHPLIE_01665	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NADHPLIE_01666	8.32e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NADHPLIE_01667	3.14e-155	-	-	-	-	-	-	-	-
NADHPLIE_01668	0.0	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylglucosaminidase
NADHPLIE_01670	1.64e-204	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
NADHPLIE_01671	5.34e-82	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NADHPLIE_01672	6.95e-35	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NADHPLIE_01673	0.0	fas	-	-	I	ko:K11533	ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931	ko00000,ko00001,ko00002,ko01000,ko01004	Beta-ketoacyl synthase, C-terminal domain
NADHPLIE_01674	1.8e-50	fas	-	-	I	ko:K11533	ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931	ko00000,ko00001,ko00002,ko01000,ko01004	Beta-ketoacyl synthase, C-terminal domain
NADHPLIE_01675	4.3e-61	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
NADHPLIE_01679	8.1e-11	-	-	-	-	-	-	-	-
NADHPLIE_01680	5.77e-76	-	-	-	S	-	-	-	competence protein
NADHPLIE_01681	9.07e-151	-	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
NADHPLIE_01682	1.27e-10	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
NADHPLIE_01683	1.9e-39	-	-	-	-	-	-	-	-
NADHPLIE_01686	4.77e-247	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
NADHPLIE_01687	2.23e-257	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NADHPLIE_01688	8.58e-291	-	2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83	-	E	ko:K00812,ko:K08969,ko:K10206,ko:K10907,ko:K14260,ko:K14261	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
NADHPLIE_01689	2.02e-57	-	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NADHPLIE_01690	3.86e-261	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NADHPLIE_01691	9.75e-231	acoB	1.2.4.1, 1.2.4.4	-	C	ko:K00162,ko:K11381,ko:K21417	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
NADHPLIE_01692	4.89e-160	acoA	1.2.4.1	-	C	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
NADHPLIE_01694	3.56e-163	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
NADHPLIE_01695	4.02e-211	iaaA	3.4.19.5	-	E	ko:K13051	-	ko00000,ko01000,ko01002	Asparaginase
NADHPLIE_01696	4.99e-182	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NADHPLIE_01697	0.0	pip	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	alpha/beta hydrolase fold
NADHPLIE_01698	2.52e-77	-	-	-	T	-	-	-	Histidine kinase
NADHPLIE_01699	0.0	-	-	-	T	-	-	-	Histidine kinase
NADHPLIE_01700	2.92e-171	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
NADHPLIE_01701	0.0	-	-	-	I	-	-	-	PAP2 superfamily
NADHPLIE_01702	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
NADHPLIE_01703	3.3e-212	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NADHPLIE_01704	0.0	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Aminotransferase class-V
NADHPLIE_01705	8.11e-201	-	-	-	S	-	-	-	Putative ABC-transporter type IV
NADHPLIE_01706	1.51e-120	pdxY	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
NADHPLIE_01707	8.35e-74	pdxY	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
NADHPLIE_01708	0.0	sdhA	1.3.5.1, 1.3.5.4, 1.4.3.16	-	C	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Succinate dehydrogenase flavoprotein subunit
NADHPLIE_01709	0.0	dprA	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
NADHPLIE_01710	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
NADHPLIE_01711	2.23e-93	yraN	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
NADHPLIE_01712	2.51e-235	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
NADHPLIE_01713	3.52e-151	safC	-	-	S	-	-	-	O-methyltransferase
NADHPLIE_01714	4.26e-222	fmt2	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
NADHPLIE_01715	8.28e-291	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NADHPLIE_01716	1.09e-165	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
NADHPLIE_01717	2.52e-112	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
NADHPLIE_01720	8.67e-312	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NADHPLIE_01721	1.55e-162	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NADHPLIE_01722	4.05e-147	clpP1	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NADHPLIE_01723	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
NADHPLIE_01724	6.56e-283	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NADHPLIE_01725	2.49e-100	rnd	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
NADHPLIE_01726	1.42e-169	rnd	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
NADHPLIE_01727	1.26e-145	-	-	-	S	-	-	-	Protein of unknown function (DUF3000)
NADHPLIE_01728	1.56e-189	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NADHPLIE_01729	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
NADHPLIE_01730	3.63e-54	-	-	-	-	-	-	-	-
NADHPLIE_01731	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NADHPLIE_01732	3.31e-122	-	-	-	S	-	-	-	Peptidase dimerisation domain
NADHPLIE_01733	5.28e-147	-	-	-	S	-	-	-	Peptidase dimerisation domain
NADHPLIE_01734	1.49e-121	-	-	-	P	-	-	-	ABC-type metal ion transport system permease component
NADHPLIE_01735	2.76e-212	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NADHPLIE_01736	3.42e-134	ppiA	5.2.1.8	-	G	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NADHPLIE_01737	9.55e-66	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
NADHPLIE_01738	8.11e-52	-	-	-	T	-	-	-	Toxic component of a toxin-antitoxin (TA) module
NADHPLIE_01739	2.96e-265	-	-	-	E	-	-	-	Belongs to the peptidase S1B family
NADHPLIE_01740	6.15e-46	-	-	-	-	-	-	-	-
NADHPLIE_01741	5.58e-257	-	-	-	S	-	-	-	HipA-like C-terminal domain
NADHPLIE_01742	1.75e-285	hsdM	2.1.1.72, 3.1.21.3	-	V	ko:K01153,ko:K01154,ko:K03427	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
NADHPLIE_01743	9.63e-93	-	-	-	S	-	-	-	EcsC protein family
NADHPLIE_01745	2.27e-36	-	-	-	L	-	-	-	DNA integration
NADHPLIE_01746	1.3e-36	-	-	-	-	-	-	-	-
NADHPLIE_01747	6.11e-179	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
NADHPLIE_01748	2.27e-296	intA	-	-	L	-	-	-	Phage integrase family
NADHPLIE_01750	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NADHPLIE_01751	1.42e-110	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
NADHPLIE_01752	2.45e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4193)
NADHPLIE_01753	1.16e-241	-	-	-	S	-	-	-	Protein of unknown function (DUF3071)
NADHPLIE_01754	2.82e-301	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
NADHPLIE_01755	0.0	gyrA2	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
NADHPLIE_01756	1.01e-220	gyrA2	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
NADHPLIE_01757	0.0	lhr	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
NADHPLIE_01758	4.59e-215	lhr	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
NADHPLIE_01759	0.0	lhr	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
NADHPLIE_01760	1.12e-49	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
NADHPLIE_01761	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
NADHPLIE_01762	0.0	gyrB2	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
NADHPLIE_01763	1.7e-24	-	-	-	S	ko:K21688	-	ko00000	G5
NADHPLIE_01764	5.16e-180	-	-	-	S	ko:K21688	-	ko00000	G5
NADHPLIE_01765	1.05e-77	trxA	1.8.1.9	-	O	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	ko00000,ko00001,ko01000,ko03110	Belongs to the thioredoxin family
NADHPLIE_01766	3.88e-152	-	-	-	F	-	-	-	Domain of unknown function (DUF4916)
NADHPLIE_01767	2.38e-200	-	-	-	I	-	-	-	Alpha/beta hydrolase family
NADHPLIE_01769	0.0	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
NADHPLIE_01770	2.17e-93	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
NADHPLIE_01771	0.0	-	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2183)
NADHPLIE_01772	0.0	ptrB	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Peptidase, S9A B C family, catalytic domain protein
NADHPLIE_01773	3.62e-245	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NADHPLIE_01774	1.51e-298	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
NADHPLIE_01775	4.67e-173	crp	-	-	K	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
NADHPLIE_01776	0.0	pon1	-	-	M	-	-	-	Transglycosylase
NADHPLIE_01777	5.01e-276	namA	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
NADHPLIE_01778	4.9e-288	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
NADHPLIE_01779	1.2e-179	-	-	-	K	-	-	-	DeoR C terminal sensor domain
NADHPLIE_01780	0.0	galT	2.7.7.12	-	C	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, N-terminal domain
NADHPLIE_01781	2.4e-296	galK	2.7.1.6, 2.7.7.12	-	G	ko:K00849,ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
NADHPLIE_01782	7.11e-194	-	-	-	EGP	-	-	-	Sugar (and other) transporter
NADHPLIE_01783	1.86e-58	-	-	-	EGP	-	-	-	Sugar (and other) transporter
NADHPLIE_01784	3.23e-58	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
NADHPLIE_01785	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
NADHPLIE_01786	2.18e-139	-	-	-	-	-	-	-	-
NADHPLIE_01789	9.1e-157	spoU	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NADHPLIE_01790	7.7e-77	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	Putative cell wall binding repeat
NADHPLIE_01791	3.53e-38	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	Putative cell wall binding repeat
NADHPLIE_01792	6.1e-234	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	FES
NADHPLIE_01793	3.75e-142	-	-	-	-	-	-	-	-
NADHPLIE_01794	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NADHPLIE_01795	3.38e-98	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NADHPLIE_01796	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NADHPLIE_01797	2.57e-81	-	-	-	T	-	-	-	Forkhead associated domain
NADHPLIE_01798	5.65e-101	-	-	-	B	-	-	-	Belongs to the OprB family
NADHPLIE_01799	8.19e-212	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
NADHPLIE_01800	0.0	-	-	-	E	-	-	-	Transglutaminase-like superfamily
NADHPLIE_01801	1.29e-298	-	-	-	S	-	-	-	Protein of unknown function DUF58
NADHPLIE_01802	6.06e-232	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
NADHPLIE_01803	3.91e-84	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
NADHPLIE_01804	0.0	-	-	-	S	-	-	-	Fibronectin type 3 domain
NADHPLIE_01805	1.88e-81	-	-	-	S	-	-	-	Fibronectin type 3 domain
NADHPLIE_01806	1.51e-295	-	-	-	S	-	-	-	Fibronectin type 3 domain
NADHPLIE_01807	0.0	pknK	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
NADHPLIE_01809	9.73e-258	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
NADHPLIE_01810	6.44e-161	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
NADHPLIE_01811	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
NADHPLIE_01812	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	Belongs to the helicase family. UvrD subfamily
NADHPLIE_01813	1.61e-193	-	-	-	K	-	-	-	-acetyltransferase
NADHPLIE_01814	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
NADHPLIE_01815	1.76e-86	gsiA	-	-	P	ko:K02031,ko:K02032,ko:K12371,ko:K13892	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NADHPLIE_01816	2.84e-53	-	-	-	L	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
NADHPLIE_01817	3.77e-32	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
NADHPLIE_01818	3.06e-79	-	-	-	L	-	-	-	Transposase
NADHPLIE_01819	3.83e-125	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NADHPLIE_01820	3.31e-26	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NADHPLIE_01821	1.15e-206	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NADHPLIE_01822	0.0	rnj	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NADHPLIE_01823	0.0	pepN	3.4.11.2	-	E	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Peptidase family M1 domain
NADHPLIE_01824	0.0	vpr	-	-	O	-	-	-	Subtilase family
NADHPLIE_01825	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NADHPLIE_01826	6.43e-160	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NADHPLIE_01827	0.0	-	-	-	S	-	-	-	zinc finger
NADHPLIE_01828	1.05e-144	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
NADHPLIE_01829	7.65e-293	aspB	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class-V
NADHPLIE_01830	5.54e-202	ppx1	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
NADHPLIE_01831	6.27e-167	tmp1	-	-	S	-	-	-	Domain of unknown function (DUF4391)
NADHPLIE_01832	3.96e-46	thiF	2.7.7.73, 2.7.7.80, 2.8.1.11	-	H	ko:K03148,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
NADHPLIE_01833	3.32e-132	thiF	2.7.7.73, 2.7.7.80, 2.8.1.11	-	H	ko:K03148,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
NADHPLIE_01834	0.0	-	-	-	OP	-	-	-	Sulfurtransferase TusA
NADHPLIE_01835	9.29e-142	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
NADHPLIE_01836	8.66e-60	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
NADHPLIE_01837	1.04e-59	-	-	-	K	-	-	-	Transcriptional regulator
NADHPLIE_01838	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
NADHPLIE_01839	0.00013	-	-	-	TV	ko:K05792	-	ko00000	HNH endonuclease
NADHPLIE_01844	5.22e-45	-	-	-	K	-	-	-	Helix-turn-helix domain
NADHPLIE_01845	5.22e-263	-	-	-	S	ko:K06919	-	ko00000	Poxvirus D5 protein-like
NADHPLIE_01847	2.25e-42	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
NADHPLIE_01848	6.33e-215	-	-	-	S	-	-	-	Relaxase/Mobilisation nuclease domain
NADHPLIE_01849	3.08e-43	-	-	-	S	-	-	-	acid phosphatase activity
NADHPLIE_01850	1.27e-123	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Involved in chromosome partitioning
NADHPLIE_01851	8.2e-39	-	-	-	-	-	-	-	-
NADHPLIE_01852	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
NADHPLIE_01853	0.0	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	modification (methylase) protein of type I restriction-modification system K03427
NADHPLIE_01854	5.34e-186	-	-	-	-	-	-	-	-
NADHPLIE_01855	1.57e-129	-	3.1.21.3	-	L	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
NADHPLIE_01856	0.0	-	-	-	L	-	-	-	Recombinase
NADHPLIE_01857	1.22e-15	tam	2.1.1.144	-	S	ko:K00598	-	ko00000,ko01000	Methyltransferase domain
NADHPLIE_01858	2.07e-301	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NADHPLIE_01860	1.77e-72	-	-	-	L	-	-	-	RelB antitoxin
NADHPLIE_01862	8.3e-171	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NADHPLIE_01863	1.82e-310	-	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
NADHPLIE_01865	1.68e-240	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
NADHPLIE_01866	7.42e-41	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
NADHPLIE_01867	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	helicase superfamily c-terminal domain
NADHPLIE_01868	4.99e-278	steT	-	-	E	ko:K03294	-	ko00000	amino acid
NADHPLIE_01871	0.0	-	-	-	-	-	-	-	-
NADHPLIE_01872	0.0	-	-	-	U	ko:K06956	-	ko00000	Sodium:dicarboxylate symporter family
NADHPLIE_01873	3.25e-72	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Conserved hypothetical protein 95
NADHPLIE_01874	8.5e-54	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Conserved hypothetical protein 95
NADHPLIE_01875	1.65e-140	-	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
NADHPLIE_01876	1.25e-106	-	-	-	O	-	-	-	Hsp20/alpha crystallin family
NADHPLIE_01877	3.2e-81	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
NADHPLIE_01878	2.07e-33	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
NADHPLIE_01879	9.23e-139	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NADHPLIE_01880	3.56e-47	-	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
NADHPLIE_01881	2.4e-80	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
NADHPLIE_01882	1.13e-260	-	-	-	EK	ko:K05825,ko:K18907	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko00002,ko01000,ko01504,ko03000	Alanine-glyoxylate amino-transferase
NADHPLIE_01883	2.42e-84	-	-	-	EK	ko:K05825,ko:K18907	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko00002,ko01000,ko01504,ko03000	Alanine-glyoxylate amino-transferase
NADHPLIE_01884	5.53e-131	-	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
NADHPLIE_01885	1.84e-280	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
NADHPLIE_01886	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NADHPLIE_01887	4.14e-212	-	-	-	P	-	-	-	Cation efflux family
NADHPLIE_01888	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NADHPLIE_01889	8.06e-175	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase C26
NADHPLIE_01890	0.0	yjjK	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter
NADHPLIE_01891	1.04e-76	-	-	-	S	-	-	-	Protein of unknown function (DUF3039)
NADHPLIE_01892	3.67e-105	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NADHPLIE_01893	1.07e-66	-	-	-	-	-	-	-	-
NADHPLIE_01894	3.34e-103	-	-	-	-	-	-	-	-
NADHPLIE_01895	2.17e-147	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
NADHPLIE_01896	2.72e-34	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
NADHPLIE_01897	1.56e-179	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NADHPLIE_01898	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
NADHPLIE_01899	1.26e-118	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
NADHPLIE_01901	3.4e-315	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NADHPLIE_01902	6.69e-173	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NADHPLIE_01903	9.76e-153	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NADHPLIE_01904	4.61e-227	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
NADHPLIE_01907	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
NADHPLIE_01908	8.73e-32	-	-	-	L	-	-	-	Transposase
NADHPLIE_01909	0.0	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NADHPLIE_01910	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NADHPLIE_01912	1.22e-221	-	-	-	K	-	-	-	Putative sugar-binding domain
NADHPLIE_01913	1.45e-283	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
NADHPLIE_01914	0.0	-	2.7.1.53	-	G	ko:K00880	ko00040,ko00053,map00040,map00053	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
NADHPLIE_01915	3.12e-220	-	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
NADHPLIE_01916	8.39e-167	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Class II Aldolase and Adducin N-terminal domain
NADHPLIE_01917	4.2e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NADHPLIE_01918	1.03e-201	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NADHPLIE_01919	6.64e-170	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NADHPLIE_01920	1.56e-111	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
NADHPLIE_01921	8.84e-134	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
NADHPLIE_01923	1.75e-154	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
NADHPLIE_01924	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
NADHPLIE_01925	1.53e-213	-	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
NADHPLIE_01926	2.45e-218	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
NADHPLIE_01927	3.33e-206	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
NADHPLIE_01928	1.35e-68	-	-	-	E	-	-	-	Serine carboxypeptidase
NADHPLIE_01929	5.53e-299	-	-	-	E	-	-	-	Serine carboxypeptidase
NADHPLIE_01930	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
NADHPLIE_01932	3.07e-183	-	-	-	S	-	-	-	Domain of unknown function (DUF4194)
NADHPLIE_01933	4.23e-192	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
NADHPLIE_01934	2.09e-207	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NADHPLIE_01935	1.94e-83	-	-	-	K	-	-	-	Protein of unknown function, DUF488
NADHPLIE_01936	7.09e-153	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NADHPLIE_01937	1.55e-116	-	-	-	K	-	-	-	FR47-like protein
NADHPLIE_01938	1.08e-73	-	-	-	K	-	-	-	Transcriptional regulator
NADHPLIE_01939	9.65e-50	-	-	-	F	-	-	-	Hydrolase of X-linked nucleoside diphosphate N terminal
NADHPLIE_01941	4.46e-46	-	-	-	S	-	-	-	Carbon-nitrogen hydrolase
NADHPLIE_01943	1.7e-236	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
NADHPLIE_01944	1.01e-98	qseC	2.7.13.3	-	T	ko:K02484,ko:K07637,ko:K07643,ko:K07645,ko:K07649,ko:K07653,ko:K18351	ko01502,ko01503,ko02020,ko02024,map01502,map01503,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	Histidine kinase
NADHPLIE_01945	2.32e-169	-	-	-	S	-	-	-	SOS response associated peptidase (SRAP)
NADHPLIE_01947	4.41e-102	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NADHPLIE_01948	5.39e-224	-	-	-	M	-	-	-	heme binding
NADHPLIE_01949	1.3e-37	-	-	-	EGP	ko:K03446,ko:K03466,ko:K03762,ko:K08217	-	br01600,ko00000,ko00002,ko01504,ko02000,ko03036	Major facilitator Superfamily
NADHPLIE_01950	6.7e-128	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
NADHPLIE_01952	1.65e-92	-	-	-	-	-	-	-	-
NADHPLIE_01953	1.4e-90	-	-	-	-	-	-	-	-
NADHPLIE_01954	2.58e-15	-	-	-	CE	ko:K03294	-	ko00000	Amino acid permease
NADHPLIE_01955	3e-121	-	-	-	S	-	-	-	Putative ABC-transporter type IV
NADHPLIE_01956	1.02e-80	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
NADHPLIE_01957	1.62e-35	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
NADHPLIE_01958	2.06e-53	-	-	-	V	-	-	-	VanZ like family
NADHPLIE_01959	1.78e-138	-	-	-	V	-	-	-	VanZ like family
NADHPLIE_01960	3.14e-188	-	-	-	KT	-	-	-	RESPONSE REGULATOR receiver
NADHPLIE_01961	3.34e-92	pdxH	-	-	S	ko:K07006	-	ko00000	Pfam:Pyridox_oxidase
NADHPLIE_01962	2.32e-186	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
NADHPLIE_01963	1.99e-170	-	-	-	C	-	-	-	Putative TM nitroreductase
NADHPLIE_01964	2.68e-63	-	-	-	-	-	-	-	-
NADHPLIE_01965	8.42e-65	-	-	-	-	-	-	-	-
NADHPLIE_01967	0.0	treS_1	-	-	G	-	-	-	Alpha amylase, catalytic domain
NADHPLIE_01968	1.08e-101	-	-	-	S	-	-	-	Bacterial PH domain
NADHPLIE_01969	1.65e-177	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
NADHPLIE_01970	1.01e-87	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NADHPLIE_01971	9.27e-309	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NADHPLIE_01973	6.24e-244	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NADHPLIE_01974	5.93e-187	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NADHPLIE_01975	1.17e-78	-	-	-	-	-	-	-	-
NADHPLIE_01976	1.99e-299	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NADHPLIE_01977	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase N terminus
NADHPLIE_01978	1.58e-149	-	-	-	S	-	-	-	ABC-2 family transporter protein
NADHPLIE_01979	2.76e-144	-	-	-	S	-	-	-	ABC-2 family transporter protein
NADHPLIE_01980	7.39e-226	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NADHPLIE_01981	6.98e-78	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
NADHPLIE_01982	3.05e-159	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
NADHPLIE_01983	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
NADHPLIE_01984	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
NADHPLIE_01985	5.24e-150	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
NADHPLIE_01986	1.31e-142	-	-	-	-	-	-	-	-
NADHPLIE_01987	1.88e-174	tlyA	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
NADHPLIE_01989	3.59e-241	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
NADHPLIE_01990	6.76e-268	-	-	-	L	-	-	-	Tetratricopeptide repeat
NADHPLIE_01991	0.0	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NADHPLIE_01992	1.02e-184	-	-	-	S	-	-	-	Putative ABC-transporter type IV
NADHPLIE_01993	9.62e-142	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NADHPLIE_01994	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
NADHPLIE_01995	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
NADHPLIE_01996	2.09e-158	-	-	-	K	-	-	-	Putative DNA-binding domain
NADHPLIE_01997	5.4e-131	-	-	-	K	-	-	-	Putative DNA-binding domain
NADHPLIE_01998	3.05e-83	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
NADHPLIE_01999	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	modification (methylase) protein of type I restriction-modification system K03427
NADHPLIE_02000	2.12e-197	-	-	-	S	-	-	-	Domain of unknown function (DUF4357)
NADHPLIE_02001	3.91e-81	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
NADHPLIE_02002	2.49e-228	-	-	-	L	-	-	-	Phage integrase family
NADHPLIE_02003	5.96e-304	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
NADHPLIE_02004	1.29e-112	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NADHPLIE_02005	2.51e-234	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NADHPLIE_02006	1.75e-189	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
NADHPLIE_02007	1.34e-66	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
NADHPLIE_02008	4.12e-227	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
NADHPLIE_02009	2.57e-45	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NADHPLIE_02010	1.38e-165	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NADHPLIE_02011	1.84e-260	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NADHPLIE_02012	3.4e-84	-	-	-	-	-	-	-	-
NADHPLIE_02013	7.5e-53	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Phenylalanyl-tRNA synthetase beta