ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
NBPHLDOP_00001 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NBPHLDOP_00002 1.02e-260 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NBPHLDOP_00004 4.07e-43 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
NBPHLDOP_00005 9.09e-260 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NBPHLDOP_00006 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NBPHLDOP_00007 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NBPHLDOP_00008 5.22e-163 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NBPHLDOP_00009 5.2e-98 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NBPHLDOP_00010 1.36e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
NBPHLDOP_00011 7.5e-111 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NBPHLDOP_00012 3.26e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NBPHLDOP_00013 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
NBPHLDOP_00015 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome bd terminal oxidase subunit I
NBPHLDOP_00016 8.08e-229 - - - C - - - Cytochrome bd terminal oxidase subunit II
NBPHLDOP_00017 1.21e-48 - - - - - - - -
NBPHLDOP_00018 9.81e-138 - - - S - - - Protein of unknown function (DUF1211)
NBPHLDOP_00021 5.26e-183 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NBPHLDOP_00025 4.92e-201 p40 - - D ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain
NBPHLDOP_00026 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NBPHLDOP_00027 1.76e-165 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NBPHLDOP_00028 4.12e-128 - - - K - - - transcriptional regulator
NBPHLDOP_00029 4.35e-197 - - - G - - - Sucrose-6F-phosphate phosphohydrolase
NBPHLDOP_00030 4.92e-65 - - - - - - - -
NBPHLDOP_00033 0.0 ybfG - - M - - - peptidoglycan-binding domain-containing protein
NBPHLDOP_00034 2.08e-188 - - - S ko:K07090 - ko00000 membrane transporter protein
NBPHLDOP_00035 6.97e-133 - - - S - - - Protein of unknown function (DUF1211)
NBPHLDOP_00036 8.19e-212 - - - P - - - CorA-like Mg2+ transporter protein
NBPHLDOP_00037 3.29e-146 - - - K - - - Bacterial regulatory proteins, tetR family
NBPHLDOP_00039 2.37e-306 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NBPHLDOP_00041 0.0 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NBPHLDOP_00042 1.02e-144 - - - S - - - Membrane
NBPHLDOP_00043 4.98e-68 - - - - - - - -
NBPHLDOP_00045 4.32e-133 - - - - - - - -
NBPHLDOP_00046 2.3e-101 - - - - - - - -
NBPHLDOP_00047 4.97e-70 - - - - - - - -
NBPHLDOP_00048 1.95e-159 azlC - - E - - - branched-chain amino acid
NBPHLDOP_00049 1.83e-66 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
NBPHLDOP_00051 2.44e-40 - - - - - - - -
NBPHLDOP_00052 2.25e-185 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NBPHLDOP_00053 1.19e-150 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
NBPHLDOP_00054 0.0 - - - L - - - Transposase DDE domain
NBPHLDOP_00055 7.74e-163 kdgR - - K - - - FCD domain
NBPHLDOP_00056 3.45e-74 ps105 - - - - - - -
NBPHLDOP_00057 3.38e-210 - - - K - - - Transcriptional activator, Rgg GadR MutR family
NBPHLDOP_00058 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
NBPHLDOP_00059 6.85e-310 - - - EGP - - - Major Facilitator
NBPHLDOP_00061 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
NBPHLDOP_00062 2.34e-140 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
NBPHLDOP_00064 3.93e-142 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NBPHLDOP_00065 3.55e-222 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NBPHLDOP_00066 2.28e-136 opuCB - - E ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NBPHLDOP_00067 8.51e-286 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NBPHLDOP_00068 0.000666 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NBPHLDOP_00070 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
NBPHLDOP_00071 3.61e-46 copZ - - P - - - Heavy-metal-associated domain
NBPHLDOP_00072 3.09e-133 dpsB - - P - - - Belongs to the Dps family
NBPHLDOP_00073 2.13e-150 flp - - K ko:K21562 - ko00000,ko03000 helix_turn_helix, cAMP Regulatory protein
NBPHLDOP_00074 2.39e-183 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NBPHLDOP_00075 1.74e-293 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NBPHLDOP_00076 6.7e-135 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
NBPHLDOP_00077 7.66e-178 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
NBPHLDOP_00078 1.84e-237 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NBPHLDOP_00079 1.02e-298 - - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NBPHLDOP_00080 1.47e-60 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NBPHLDOP_00081 8.8e-103 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBPHLDOP_00082 6.16e-177 - - - S - - - Domain of unknown function (DUF4918)
NBPHLDOP_00083 3.34e-268 - - - - - - - -
NBPHLDOP_00084 0.0 - - - EGP - - - Major Facilitator
NBPHLDOP_00085 1.04e-139 - - - K - - - Bacterial regulatory proteins, tetR family
NBPHLDOP_00087 1.28e-166 - - - - - - - -
NBPHLDOP_00088 2.19e-289 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-type transport system involved in multi-copper enzyme maturation permease component
NBPHLDOP_00089 9.92e-212 - - - - - - - -
NBPHLDOP_00090 1.38e-155 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NBPHLDOP_00091 7.63e-85 - - - S ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
NBPHLDOP_00093 7.65e-61 - - - M - - - Peptidoglycan-binding domain 1 protein
NBPHLDOP_00094 0.0 ybfG - - M - - - peptidoglycan-binding domain-containing protein
NBPHLDOP_00096 5.43e-180 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NBPHLDOP_00097 4.95e-215 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NBPHLDOP_00098 6.4e-282 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NBPHLDOP_00099 4.4e-116 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NBPHLDOP_00100 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NBPHLDOP_00101 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NBPHLDOP_00102 4.38e-242 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NBPHLDOP_00103 1.74e-252 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NBPHLDOP_00104 8.46e-84 - - - - - - - -
NBPHLDOP_00105 1.35e-97 - - - L - - - NUDIX domain
NBPHLDOP_00106 4.62e-193 - - - EG - - - EamA-like transporter family
NBPHLDOP_00107 3.35e-125 - - - S - - - Phospholipase A2
NBPHLDOP_00109 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
NBPHLDOP_00110 1.35e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
NBPHLDOP_00111 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
NBPHLDOP_00112 2.31e-277 - - - - - - - -
NBPHLDOP_00114 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NBPHLDOP_00115 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
NBPHLDOP_00116 4.34e-75 cadC5 - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
NBPHLDOP_00117 0.0 - 3.6.3.6 - P ko:K01535 ko00190,map00190 ko00000,ko00001,ko01000 Cation transporter/ATPase, N-terminus
NBPHLDOP_00118 1.78e-208 lysR5 - - K - - - LysR substrate binding domain
NBPHLDOP_00119 3.32e-263 - - - K - - - Helix-turn-helix XRE-family like proteins
NBPHLDOP_00120 1.91e-46 - - - S - - - Phospholipase_D-nuclease N-terminal
NBPHLDOP_00121 2.26e-215 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NBPHLDOP_00122 3.78e-170 - - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NBPHLDOP_00123 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
NBPHLDOP_00124 1.45e-172 - - - - - - - -
NBPHLDOP_00125 4e-133 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
NBPHLDOP_00126 0.0 - - - - - - - -
NBPHLDOP_00127 4.68e-185 - - - T - - - Calcineurin-like phosphoesterase superfamily domain
NBPHLDOP_00128 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
NBPHLDOP_00129 0.0 - - - L - - - Transposase DDE domain
NBPHLDOP_00131 4.68e-53 - - - - - - - -
NBPHLDOP_00132 2.66e-57 - - - S - - - Protein of unknown function (DUF2089)
NBPHLDOP_00133 1.64e-237 yveB - - I - - - PAP2 superfamily
NBPHLDOP_00134 2.35e-269 mccF - - V - - - LD-carboxypeptidase
NBPHLDOP_00135 6.55e-57 - - - - - - - -
NBPHLDOP_00136 2.61e-261 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
NBPHLDOP_00137 2.47e-117 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
NBPHLDOP_00138 1.17e-245 ldhD3 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NBPHLDOP_00139 1.21e-59 - - - - - - - -
NBPHLDOP_00140 2.74e-112 - - - K - - - Transcriptional regulator
NBPHLDOP_00141 1.07e-239 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 alcohol dehydrogenase
NBPHLDOP_00142 1.61e-72 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
NBPHLDOP_00143 2.42e-72 - - - S - - - Protein of unknown function (DUF1516)
NBPHLDOP_00144 0.0 XK27_07275 - - S ko:K06901 - ko00000,ko02000 permease
NBPHLDOP_00145 5.52e-61 - - - S ko:K09004 - ko00000 DsrE/DsrF-like family
NBPHLDOP_00146 6.51e-247 - - - L ko:K07482 - ko00000 Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NBPHLDOP_00147 1.01e-225 mhqA - - E ko:K15975 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NBPHLDOP_00148 6.64e-39 - - - - - - - -
NBPHLDOP_00149 1.8e-135 yoaA - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NBPHLDOP_00150 0.0 - - - - - - - -
NBPHLDOP_00152 3.46e-168 - - - S - - - WxL domain surface cell wall-binding
NBPHLDOP_00153 5.01e-172 - - - S - - - WxL domain surface cell wall-binding
NBPHLDOP_00154 2.17e-245 ynjC - - S - - - Cell surface protein
NBPHLDOP_00156 0.0 - - - L - - - Mga helix-turn-helix domain
NBPHLDOP_00157 1.45e-232 - - - S - - - Protein of unknown function (DUF805)
NBPHLDOP_00158 1.1e-76 - - - - - - - -
NBPHLDOP_00159 0.0 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
NBPHLDOP_00160 6.45e-284 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NBPHLDOP_00161 2.01e-205 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
NBPHLDOP_00162 8.09e-180 - - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
NBPHLDOP_00163 8.86e-62 - - - S - - - Thiamine-binding protein
NBPHLDOP_00164 0.0 yhgE - - V ko:K01421 - ko00000 domain protein
NBPHLDOP_00165 4.77e-130 yobS - - K - - - Bacterial regulatory proteins, tetR family
NBPHLDOP_00166 0.0 bmr3 - - EGP - - - Major Facilitator
NBPHLDOP_00168 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
NBPHLDOP_00169 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NBPHLDOP_00170 1.15e-25 - - - - - - - -
NBPHLDOP_00172 8.72e-105 - - - S - - - NUDIX domain
NBPHLDOP_00173 1.33e-276 - - - S - - - nuclear-transcribed mRNA catabolic process, no-go decay
NBPHLDOP_00174 0.0 fnq20 - - S - - - FAD-NAD(P)-binding
NBPHLDOP_00175 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
NBPHLDOP_00176 6.18e-150 - - - - - - - -
NBPHLDOP_00177 2.18e-289 - - - S ko:K06872 - ko00000 TPM domain
NBPHLDOP_00178 8.76e-178 yunE - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
NBPHLDOP_00179 6.45e-74 ywjH - - S - - - Protein of unknown function (DUF1634)
NBPHLDOP_00180 1.47e-07 - - - - - - - -
NBPHLDOP_00181 5.12e-117 - - - - - - - -
NBPHLDOP_00182 4.85e-65 - - - - - - - -
NBPHLDOP_00183 1.63e-109 - - - C - - - Flavodoxin
NBPHLDOP_00184 5.54e-50 - - - - - - - -
NBPHLDOP_00185 2.82e-36 - - - - - - - -
NBPHLDOP_00186 2.86e-219 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NBPHLDOP_00187 2.27e-94 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
NBPHLDOP_00188 1.93e-52 - - - S - - - Transglycosylase associated protein
NBPHLDOP_00189 5.77e-113 - - - S - - - Protein conserved in bacteria
NBPHLDOP_00190 4.15e-34 - - - - - - - -
NBPHLDOP_00191 8.12e-90 asp23 - - S - - - Asp23 family, cell envelope-related function
NBPHLDOP_00192 1.97e-92 asp2 - - S - - - Asp23 family, cell envelope-related function
NBPHLDOP_00193 9.28e-148 - - - S - - - Protein of unknown function (DUF969)
NBPHLDOP_00194 1.42e-195 - - - S - - - Protein of unknown function (DUF979)
NBPHLDOP_00195 1.2e-154 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NBPHLDOP_00196 3.05e-139 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
NBPHLDOP_00197 6.67e-165 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
NBPHLDOP_00198 4.01e-87 - - - - - - - -
NBPHLDOP_00199 3.36e-169 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
NBPHLDOP_00200 6.84e-189 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NBPHLDOP_00201 1.49e-177 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
NBPHLDOP_00202 1.11e-201 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NBPHLDOP_00203 3.26e-40 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
NBPHLDOP_00204 9.76e-237 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NBPHLDOP_00205 7.77e-173 - - - S - - - Protein of unknown function (DUF1129)
NBPHLDOP_00206 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NBPHLDOP_00207 1.23e-157 - - - - - - - -
NBPHLDOP_00208 1.68e-156 vanR - - K - - - response regulator
NBPHLDOP_00209 2.81e-278 hpk31 - - T - - - Histidine kinase
NBPHLDOP_00210 4.75e-304 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NBPHLDOP_00211 1.02e-103 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NBPHLDOP_00212 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NBPHLDOP_00213 2.71e-182 racD 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
NBPHLDOP_00214 3.48e-212 yvgN - - C - - - Aldo keto reductase
NBPHLDOP_00215 3.54e-187 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NBPHLDOP_00216 0.0 iolT - - EGP ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NBPHLDOP_00217 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NBPHLDOP_00218 8.47e-201 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NBPHLDOP_00219 6.58e-228 iolC 2.7.1.92 - H ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NBPHLDOP_00220 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NBPHLDOP_00221 9.62e-247 - 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
NBPHLDOP_00222 3.37e-249 iolG2 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
NBPHLDOP_00223 1.27e-223 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NBPHLDOP_00224 1.4e-204 iolJ 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
NBPHLDOP_00225 8.67e-88 yodA - - S - - - Tautomerase enzyme
NBPHLDOP_00226 3.12e-187 gntR - - K - - - rpiR family
NBPHLDOP_00227 1.27e-217 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
NBPHLDOP_00228 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
NBPHLDOP_00229 6.55e-270 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
NBPHLDOP_00230 3.01e-315 - - - S - - - O-antigen ligase like membrane protein
NBPHLDOP_00231 6.41e-196 - - - S - - - Glycosyl transferase family 2
NBPHLDOP_00232 7.56e-165 welB - - S - - - Glycosyltransferase like family 2
NBPHLDOP_00233 4.2e-208 - - - S - - - Glycosyltransferase like family 2
NBPHLDOP_00234 1.99e-192 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
NBPHLDOP_00235 0.0 - - - M - - - Glycosyl hydrolases family 25
NBPHLDOP_00236 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
NBPHLDOP_00237 1.85e-207 - - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
NBPHLDOP_00238 6.33e-254 - - - S - - - Protein conserved in bacteria
NBPHLDOP_00239 3.74e-75 - - - - - - - -
NBPHLDOP_00240 1.01e-167 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NBPHLDOP_00241 5.98e-173 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
NBPHLDOP_00242 3.1e-213 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
NBPHLDOP_00243 2.25e-207 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
NBPHLDOP_00244 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
NBPHLDOP_00245 4.84e-256 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NBPHLDOP_00246 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NBPHLDOP_00247 2.43e-103 - - - T - - - Sh3 type 3 domain protein
NBPHLDOP_00248 7.68e-174 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
NBPHLDOP_00249 2.32e-188 - - - M - - - Glycosyltransferase like family 2
NBPHLDOP_00250 1.32e-175 - - - S - - - Protein of unknown function (DUF975)
NBPHLDOP_00251 2.19e-54 - - - - - - - -
NBPHLDOP_00252 1.26e-139 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NBPHLDOP_00253 6.35e-228 draG - - O - - - ADP-ribosylglycohydrolase
NBPHLDOP_00254 0.0 - - - S - - - ABC transporter
NBPHLDOP_00255 3.54e-176 ypaC - - Q - - - Methyltransferase domain
NBPHLDOP_00256 5.19e-90 - - - S - - - COG NOG38524 non supervised orthologous group
NBPHLDOP_00258 3.02e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NBPHLDOP_00259 2.2e-176 - - - S - - - Putative threonine/serine exporter
NBPHLDOP_00260 2.51e-98 - - - S - - - Threonine/Serine exporter, ThrE
NBPHLDOP_00261 3.96e-274 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
NBPHLDOP_00262 1.04e-191 livH - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
NBPHLDOP_00263 2.87e-11 livM - - E ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
NBPHLDOP_00264 2.9e-153 livM - - E ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
NBPHLDOP_00265 3.01e-180 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
NBPHLDOP_00266 2.35e-159 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
NBPHLDOP_00267 7.59e-214 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NBPHLDOP_00268 6.06e-308 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NBPHLDOP_00269 4.1e-152 - - - G - - - Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NBPHLDOP_00270 1.01e-149 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NBPHLDOP_00271 3.24e-293 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
NBPHLDOP_00272 3.82e-167 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
NBPHLDOP_00273 2.38e-212 p75 - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
NBPHLDOP_00277 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
NBPHLDOP_00278 4.55e-206 - - - - - - - -
NBPHLDOP_00279 3.03e-158 - - - - - - - -
NBPHLDOP_00280 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
NBPHLDOP_00281 1.73e-307 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NBPHLDOP_00282 1.2e-121 - - - - - - - -
NBPHLDOP_00283 0.0 strH 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Gram-positive signal peptide protein, YSIRK family
NBPHLDOP_00284 9.12e-249 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NBPHLDOP_00285 5.43e-167 - - - K ko:K03710 - ko00000,ko03000 UTRA
NBPHLDOP_00286 9.86e-282 agaS - - G ko:K02082 - ko00000,ko01000 SIS domain
NBPHLDOP_00287 2.26e-288 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
NBPHLDOP_00288 0.0 bgaC 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Glycosyl hydrolases family 35
NBPHLDOP_00289 5.61e-108 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NBPHLDOP_00290 4.68e-206 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
NBPHLDOP_00291 3.66e-187 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
NBPHLDOP_00292 2.72e-85 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NBPHLDOP_00293 1.23e-292 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
NBPHLDOP_00294 1.01e-55 - 4.4.1.8 - E ko:K00842,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NBPHLDOP_00295 0.0 - - - L - - - Transposase DDE domain
NBPHLDOP_00296 9.35e-225 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
NBPHLDOP_00297 1.33e-252 - 3.4.11.9 - E ko:K01262 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
NBPHLDOP_00298 0.0 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NBPHLDOP_00299 2.96e-78 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NBPHLDOP_00300 2.04e-68 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
NBPHLDOP_00301 6.02e-242 - - - E - - - M42 glutamyl aminopeptidase
NBPHLDOP_00302 0.0 - - - GKT ko:K03491 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBPHLDOP_00303 4.24e-310 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
NBPHLDOP_00304 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NBPHLDOP_00305 2.16e-156 - - - S ko:K03824 - ko00000,ko01000 Acetyltransferase (GNAT) family
NBPHLDOP_00307 4.57e-123 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
NBPHLDOP_00308 6.91e-314 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NBPHLDOP_00309 2.8e-144 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
NBPHLDOP_00310 1.76e-168 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NBPHLDOP_00311 1.07e-108 thiW - - S - - - Thiamine-precursor transporter protein (ThiW)
NBPHLDOP_00312 6.12e-194 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NBPHLDOP_00313 5.42e-141 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NBPHLDOP_00314 2.31e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NBPHLDOP_00315 0.0 - - - E - - - Amino acid permease
NBPHLDOP_00316 7e-47 - - - - - - - -
NBPHLDOP_00317 2.08e-240 rbsR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
NBPHLDOP_00318 5.41e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NBPHLDOP_00319 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NBPHLDOP_00320 4.84e-198 rbsC - - U ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NBPHLDOP_00321 1.71e-215 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein domain
NBPHLDOP_00322 3.3e-208 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NBPHLDOP_00323 3.09e-56 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
NBPHLDOP_00324 0.0 pbpC - - M ko:K21467 - ko00000,ko01011 NTF2-like N-terminal transpeptidase domain
NBPHLDOP_00325 7.42e-311 - - - EGP - - - Major Facilitator
NBPHLDOP_00326 3.79e-96 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NBPHLDOP_00327 5.47e-134 - - - - - - - -
NBPHLDOP_00328 4.22e-41 - - - - - - - -
NBPHLDOP_00329 1.67e-84 - - - - - - - -
NBPHLDOP_00330 4.54e-91 - - - - - - - -
NBPHLDOP_00331 1.28e-89 - - - S - - - Protein of unknown function (DUF1093)
NBPHLDOP_00332 1.29e-122 - - - - - - - -
NBPHLDOP_00333 1.38e-49 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NBPHLDOP_00334 0.0 - - - L - - - Transposase DDE domain
NBPHLDOP_00335 6.45e-91 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NBPHLDOP_00336 9.65e-163 - - - - - - - -
NBPHLDOP_00337 8.53e-139 - - - - - - - -
NBPHLDOP_00338 1.17e-173 - - - - - - - -
NBPHLDOP_00339 0.0 frdC 1.3.5.1, 1.3.5.4 - C ko:K00239,ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 ko00000,ko00001,ko00002,ko01000 HI0933-like protein
NBPHLDOP_00340 7.29e-267 - - - GKT - - - transcriptional antiterminator
NBPHLDOP_00341 1.7e-224 - - - GKT - - - transcriptional antiterminator
NBPHLDOP_00342 4.1e-67 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NBPHLDOP_00343 6.84e-293 - - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NBPHLDOP_00344 2.22e-93 - - - - - - - -
NBPHLDOP_00345 6.47e-208 - 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
NBPHLDOP_00346 1.4e-152 - - - S - - - Zeta toxin
NBPHLDOP_00347 3.2e-203 - - - K - - - Sugar-specific transcriptional regulator TrmB
NBPHLDOP_00348 9.64e-191 - - - S - - - Sulfite exporter TauE/SafE
NBPHLDOP_00349 5.02e-230 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 Ornithine cyclodeaminase/mu-crystallin family
NBPHLDOP_00350 1.91e-191 - 3.1.1.24 - S ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Alpha/beta hydrolase family
NBPHLDOP_00354 1.72e-242 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
NBPHLDOP_00355 1.36e-15 - - - P - - - Type I phosphodiesterase / nucleotide pyrophosphatase
NBPHLDOP_00356 8.68e-211 pkn1 - - S - - - Sulfatase-modifying factor enzyme 1
NBPHLDOP_00357 2.97e-170 - - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
NBPHLDOP_00358 1.91e-253 ydeM3 - - C ko:K06871 - ko00000 Iron-sulfur cluster-binding domain
NBPHLDOP_00359 4.26e-221 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
NBPHLDOP_00360 7.79e-301 dcuC - - C ko:K03326 - ko00000,ko02000 Tripartite ATP-independent periplasmic transporter, DctM component
NBPHLDOP_00361 2.36e-116 - - - K - - - Acetyltransferase (GNAT) family
NBPHLDOP_00362 2.91e-175 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
NBPHLDOP_00363 2.85e-205 estA - CE1 S ko:K03930 - ko00000,ko01000 Putative esterase
NBPHLDOP_00364 1.23e-193 - - - G ko:K02796,ko:K17467 ko00030,ko00051,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
NBPHLDOP_00365 3.94e-173 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
NBPHLDOP_00366 1.12e-116 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NBPHLDOP_00367 8.5e-91 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NBPHLDOP_00368 0.0 - - - K ko:K19505 - ko00000,ko03000 Sigma-54 interaction domain
NBPHLDOP_00369 1.91e-303 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Sigma-54 factor, core binding domain
NBPHLDOP_00370 0.0 - - - K ko:K02538 - ko00000,ko03000 PRD domain
NBPHLDOP_00371 3.15e-103 ptsN 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 - G ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 phosphoenolpyruvate-dependent sugar phosphotransferase system
NBPHLDOP_00372 4.44e-224 - 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
NBPHLDOP_00373 8.68e-106 - 2.7.1.202 - G ko:K02768 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBPHLDOP_00374 1.08e-63 - 2.7.1.202 - G ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NBPHLDOP_00375 4.97e-220 - - - G ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 Phosphotransferase System
NBPHLDOP_00376 1.29e-233 - - - G - - - Domain of unknown function (DUF4432)
NBPHLDOP_00377 1.4e-173 - 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Pfam:DUF1498
NBPHLDOP_00378 0.0 xylB 2.7.1.17, 2.7.1.53 - G ko:K00854,ko:K00880 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the FGGY kinase family
NBPHLDOP_00379 2.27e-247 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
NBPHLDOP_00380 1.21e-98 - - - G ko:K11201 - ko00000,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBPHLDOP_00381 0.0 pts31BC - - G ko:K11202,ko:K11203 - ko00000,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NBPHLDOP_00382 2.7e-291 malY 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase class I and II
NBPHLDOP_00383 0.0 - - - G - - - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBPHLDOP_00384 0.0 - - - K - - - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBPHLDOP_00385 8.51e-204 - 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
NBPHLDOP_00386 0.0 - 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NBPHLDOP_00387 1.09e-38 - - - - - - - -
NBPHLDOP_00388 6.37e-82 - - - L ko:K07484 - ko00000 IS66 Orf2 like protein
NBPHLDOP_00389 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
NBPHLDOP_00390 2.6e-188 - 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
NBPHLDOP_00391 5.33e-98 - 2.7.1.191, 2.7.1.203 - G ko:K02793,ko:K17464 ko00030,ko00051,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NBPHLDOP_00392 5.98e-111 - 2.7.1.203 - G ko:K17465 ko00030,ko01120,ko02060,map00030,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NBPHLDOP_00393 5.6e-170 - - - G ko:K17466 ko00030,ko01120,ko02060,map00030,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
NBPHLDOP_00394 2.58e-196 - - - G ko:K02796,ko:K17467 ko00030,ko00051,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
NBPHLDOP_00395 1.83e-279 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
NBPHLDOP_00396 1.05e-146 dhaL 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 - S ko:K00863,ko:K05879 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak2
NBPHLDOP_00397 1.77e-237 - 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
NBPHLDOP_00398 5.39e-152 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Orotidine 5'-phosphate decarboxylase / HUMPS family
NBPHLDOP_00399 5.82e-130 hxlB 5.3.1.27 - M ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 sugar phosphate isomerase involved in capsule formation
NBPHLDOP_00400 5.41e-171 - - - K ko:K03710 - ko00000,ko03000 UTRA
NBPHLDOP_00401 7.05e-312 - - - E ko:K19956 ko00051,map00051 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
NBPHLDOP_00402 6.55e-224 - - - K - - - sugar-binding domain protein
NBPHLDOP_00403 5.02e-186 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
NBPHLDOP_00404 1.24e-89 - 2.7.1.206 - G ko:K02812 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NBPHLDOP_00405 4.08e-112 - 2.7.1.206 - G ko:K02813 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NBPHLDOP_00406 3.93e-184 - - - U ko:K02746,ko:K02795,ko:K02814 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
NBPHLDOP_00407 4.49e-197 manZ - - G ko:K02796,ko:K02815 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
NBPHLDOP_00408 2.01e-212 kbaY 4.1.2.13, 4.1.2.40 - G ko:K01624,ko:K08302 ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
NBPHLDOP_00409 0.0 sdcS - - P ko:K14445 - ko00000,ko02000 transporter
NBPHLDOP_00410 1.16e-303 - - - C - - - FAD dependent oxidoreductase
NBPHLDOP_00411 2.07e-204 - - - K - - - Transcriptional regulator, LysR family
NBPHLDOP_00412 1.12e-205 XK27_10120 - - K - - - S-adenosyl-l-methionine hydroxide adenosyltransferase
NBPHLDOP_00413 1.05e-127 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
NBPHLDOP_00414 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NBPHLDOP_00415 3.99e-192 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
NBPHLDOP_00416 2.39e-28 - - - K - - - helix_turn_helix, arabinose operon control protein
NBPHLDOP_00417 4.98e-68 - - - - - - - -
NBPHLDOP_00419 0.0 - - - K - - - Sigma-54 interaction domain
NBPHLDOP_00420 1.17e-95 - - - G ko:K02744 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NBPHLDOP_00421 2.66e-117 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NBPHLDOP_00422 6.62e-197 levC - - M ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
NBPHLDOP_00423 7.5e-200 levD - - G ko:K02771 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
NBPHLDOP_00424 4.22e-70 - - - - - - - -
NBPHLDOP_00426 2.94e-162 - - - S - - - Haloacid dehalogenase-like hydrolase
NBPHLDOP_00427 8.29e-174 - - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
NBPHLDOP_00428 5.04e-147 - 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Orotidine 5'-phosphate decarboxylase / HUMPS family
NBPHLDOP_00429 2.35e-125 - 5.3.1.27 - M ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
NBPHLDOP_00430 0.0 - 2.7.1.197 - G ko:K02798,ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBPHLDOP_00431 5.75e-286 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
NBPHLDOP_00432 1.27e-248 - 1.5.1.28 - C ko:K04940 - ko00000,ko01000 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
NBPHLDOP_00433 2.48e-173 yxeO - - E ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NBPHLDOP_00434 5.72e-205 - - - ET ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
NBPHLDOP_00435 6.06e-147 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NBPHLDOP_00436 1.32e-153 - - - P ko:K16958 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NBPHLDOP_00437 1.12e-304 proP - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Sugar (and other) transporter
NBPHLDOP_00439 1.33e-17 - - - S - - - YvrJ protein family
NBPHLDOP_00440 2e-185 - - - M - - - hydrolase, family 25
NBPHLDOP_00441 2.9e-171 ypiA - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NBPHLDOP_00442 1.25e-148 - - - C - - - Flavodoxin
NBPHLDOP_00443 6.23e-113 - - - K - - - Bacterial regulatory proteins, tetR family
NBPHLDOP_00444 5.69e-238 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NBPHLDOP_00445 6.07e-155 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NBPHLDOP_00446 3.74e-53 - - - K - - - Helix-turn-helix XRE-family like proteins
NBPHLDOP_00447 9.99e-86 - - - S - - - Phage derived protein Gp49-like (DUF891)
NBPHLDOP_00448 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
NBPHLDOP_00449 2.62e-194 - - - S - - - hydrolase
NBPHLDOP_00450 6.3e-60 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
NBPHLDOP_00451 1.15e-237 - - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
NBPHLDOP_00452 1.48e-109 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NBPHLDOP_00453 2.18e-177 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
NBPHLDOP_00454 7.9e-196 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
NBPHLDOP_00455 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
NBPHLDOP_00456 1.51e-90 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NBPHLDOP_00457 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NBPHLDOP_00458 1.18e-157 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
NBPHLDOP_00459 1.94e-248 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
NBPHLDOP_00460 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
NBPHLDOP_00462 0.0 pip - - V ko:K01421 - ko00000 domain protein
NBPHLDOP_00463 1.91e-201 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NBPHLDOP_00464 5.84e-253 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
NBPHLDOP_00465 4.99e-105 - - - - - - - -
NBPHLDOP_00466 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
NBPHLDOP_00467 7.24e-23 - - - - - - - -
NBPHLDOP_00468 2.11e-132 - - - K - - - Bacterial regulatory proteins, tetR family
NBPHLDOP_00469 2.1e-78 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
NBPHLDOP_00470 4.95e-134 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
NBPHLDOP_00471 1.03e-242 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
NBPHLDOP_00472 1.05e-101 - - - O - - - OsmC-like protein
NBPHLDOP_00473 0.0 - - - L - - - Exonuclease
NBPHLDOP_00474 5.14e-65 yczG - - K - - - Helix-turn-helix domain
NBPHLDOP_00475 4.02e-262 yceJ - - EGP ko:K08221 - ko00000,ko02000 transporter
NBPHLDOP_00476 2.07e-140 ydfF - - K - - - Transcriptional
NBPHLDOP_00477 6.8e-140 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
NBPHLDOP_00478 2.65e-215 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
NBPHLDOP_00479 0.0 cidC 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NBPHLDOP_00481 1.22e-249 pbpE - - V - - - Beta-lactamase
NBPHLDOP_00482 1.35e-186 - - - H - - - Protein of unknown function (DUF1698)
NBPHLDOP_00483 1.15e-183 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
NBPHLDOP_00484 0.0 - 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 Glutamine synthetase, catalytic domain
NBPHLDOP_00485 6.16e-285 - - - S ko:K07045 - ko00000 Amidohydrolase
NBPHLDOP_00486 0.0 - - - E - - - Amino acid permease
NBPHLDOP_00487 1.68e-98 - - - K - - - helix_turn_helix, mercury resistance
NBPHLDOP_00488 9.58e-211 - - - S - - - reductase
NBPHLDOP_00489 1.5e-256 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NBPHLDOP_00490 4.55e-76 ydeP - - K - - - Transcriptional regulator, HxlR family
NBPHLDOP_00491 1.68e-124 - - - - - - - -
NBPHLDOP_00492 0.0 - 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NBPHLDOP_00493 1.54e-75 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
NBPHLDOP_00494 3.96e-293 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NBPHLDOP_00495 4.8e-66 licB2 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NBPHLDOP_00496 0.0 - - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
NBPHLDOP_00497 7.9e-136 tnpR1 - - L - - - Resolvase, N terminal domain
NBPHLDOP_00498 0.0 yvcC - - M - - - Cna protein B-type domain
NBPHLDOP_00499 8.54e-213 yvcC - - M - - - Cna protein B-type domain
NBPHLDOP_00500 8.63e-164 - - - M - - - domain protein
NBPHLDOP_00501 1.25e-236 - - - M - - - LPXTG cell wall anchor motif
NBPHLDOP_00502 3.16e-258 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
NBPHLDOP_00503 1.05e-167 XK27_12140 - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NBPHLDOP_00504 0.0 - - - S - - - Psort location CytoplasmicMembrane, score
NBPHLDOP_00505 9.4e-165 - - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
NBPHLDOP_00506 3.6e-253 - 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NBPHLDOP_00508 9.72e-182 - - - V - - - ATPases associated with a variety of cellular activities
NBPHLDOP_00509 2.77e-271 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
NBPHLDOP_00510 2.15e-122 - - - - - - - -
NBPHLDOP_00511 0.0 prtP 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NBPHLDOP_00512 0.0 prtP 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NBPHLDOP_00513 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
NBPHLDOP_00514 0.0 ycaM - - E - - - amino acid
NBPHLDOP_00515 5.77e-118 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
NBPHLDOP_00516 8.19e-212 - - - K - - - Transcriptional regulator, LysR family
NBPHLDOP_00517 8.24e-143 - - - G - - - Xylose isomerase-like TIM barrel
NBPHLDOP_00518 2.09e-115 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
NBPHLDOP_00519 2.15e-44 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
NBPHLDOP_00520 1.53e-211 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NBPHLDOP_00521 2.21e-275 - - - EGP - - - Major Facilitator Superfamily
NBPHLDOP_00522 3.63e-216 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NBPHLDOP_00523 1.65e-207 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
NBPHLDOP_00524 2.2e-222 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NBPHLDOP_00525 2.14e-24 - - - - - - - -
NBPHLDOP_00527 5.52e-286 int3 - - L - - - Belongs to the 'phage' integrase family
NBPHLDOP_00532 4.87e-173 - - - - - - - -
NBPHLDOP_00533 2.33e-25 - - - E - - - Zn peptidase
NBPHLDOP_00534 1.51e-80 - - - K - - - Helix-turn-helix XRE-family like proteins
NBPHLDOP_00537 4.03e-202 ps305 - - S - - - Protein of unknown function (Hypoth_ymh)
NBPHLDOP_00538 2.23e-179 - - - S - - - ORF6N domain
NBPHLDOP_00540 1.66e-59 - - - S - - - Domain of unknown function (DUF1883)
NBPHLDOP_00546 7.76e-181 - - - L - - - Helix-turn-helix domain
NBPHLDOP_00547 5.09e-199 pi346 - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
NBPHLDOP_00549 3.84e-94 - - - - - - - -
NBPHLDOP_00550 6.1e-172 - - - - - - - -
NBPHLDOP_00553 4.76e-105 - - - - - - - -
NBPHLDOP_00555 1.21e-242 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
NBPHLDOP_00556 0.000324 - - - S - - - CsbD-like
NBPHLDOP_00557 4.05e-206 - - - - - - - -
NBPHLDOP_00558 8.29e-74 - - - - - - - -
NBPHLDOP_00559 2.11e-69 - - - L ko:K07483 - ko00000 4.5 Transposon and IS
NBPHLDOP_00560 2.5e-174 - - - L - - - Helix-turn-helix domain
NBPHLDOP_00561 2.46e-215 - - - L ko:K07497 - ko00000 hmm pf00665
NBPHLDOP_00562 1.25e-200 - - - L ko:K07497 - ko00000 4.5 Transposon and IS
NBPHLDOP_00567 6.78e-42 - - - - - - - -
NBPHLDOP_00568 1.71e-283 - - - - - - - -
NBPHLDOP_00569 2.95e-311 - - - M - - - Domain of unknown function (DUF5011)
NBPHLDOP_00572 0.0 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
NBPHLDOP_00573 0.0 - - - S - - - domain, Protein
NBPHLDOP_00575 1.77e-137 - - - - - - - -
NBPHLDOP_00576 0.0 - - - S - - - COG0433 Predicted ATPase
NBPHLDOP_00577 2.45e-244 - - - M ko:K21471,ko:K21472 - ko00000,ko01000,ko01002,ko01011 cysteine-type peptidase activity
NBPHLDOP_00582 0.000934 - - - S - - - Ribbon-helix-helix protein, copG family
NBPHLDOP_00584 4.83e-295 - - - S - - - COG0790 FOG TPR repeat, SEL1 subfamily
NBPHLDOP_00586 0.0 - - - L - - - Protein of unknown function (DUF3991)
NBPHLDOP_00588 6.1e-88 - - - - - - - -
NBPHLDOP_00589 4.79e-21 - - - - - - - -
NBPHLDOP_00590 3.24e-64 - - - - - - - -
NBPHLDOP_00591 3.16e-23 - - - - - - - -
NBPHLDOP_00593 1.72e-103 - - - - - - - -
NBPHLDOP_00594 1.15e-200 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
NBPHLDOP_00596 1.56e-154 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
NBPHLDOP_00598 0.0 eriC - - P ko:K03281 - ko00000 chloride
NBPHLDOP_00599 1.69e-107 - - - L - - - Transposase DDE domain
NBPHLDOP_00600 1.51e-77 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
NBPHLDOP_00601 7.52e-87 repA - - S - - - Replication initiator protein A
NBPHLDOP_00602 4.59e-58 - - - - - - - -
NBPHLDOP_00603 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
NBPHLDOP_00604 5.26e-164 tnp1216 - - L ko:K07498 - ko00000 DDE domain
NBPHLDOP_00605 1.16e-248 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NBPHLDOP_00606 1.19e-107 - - - L - - - Transposase DDE domain
NBPHLDOP_00607 1.51e-77 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
NBPHLDOP_00608 1.12e-150 tnp1216 - - L ko:K07498 - ko00000 DDE domain
NBPHLDOP_00609 3.25e-224 - 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NBPHLDOP_00610 5.86e-190 - - - G - - - PTS system mannose/fructose/sorbose family IID component
NBPHLDOP_00611 1.65e-184 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
NBPHLDOP_00612 2.1e-114 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NBPHLDOP_00613 5.68e-91 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NBPHLDOP_00614 2.3e-169 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NBPHLDOP_00615 9.41e-176 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
NBPHLDOP_00617 3.33e-133 tnpR - - L - - - Resolvase, N terminal domain
NBPHLDOP_00618 3.3e-315 xylP - - G - - - MFS/sugar transport protein
NBPHLDOP_00619 7.69e-134 - - - - - - - -
NBPHLDOP_00620 8.93e-47 - - - - - - - -
NBPHLDOP_00621 1.19e-107 - - - L - - - Transposase DDE domain
NBPHLDOP_00622 1.51e-77 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
NBPHLDOP_00623 5.96e-28 - - - S - - - Uncharacterised protein family (UPF0236)
NBPHLDOP_00624 1.04e-187 is18 - - L - - - Integrase core domain
NBPHLDOP_00625 2.78e-25 - - - L ko:K07483 - ko00000 transposase activity
NBPHLDOP_00626 5.16e-210 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NBPHLDOP_00627 2.73e-140 - - - S - - - NADPH-dependent FMN reductase
NBPHLDOP_00628 2.99e-309 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
NBPHLDOP_00629 2.78e-25 - - - L ko:K07483 - ko00000 transposase activity
NBPHLDOP_00630 1.04e-187 is18 - - L - - - Integrase core domain
NBPHLDOP_00631 0.0 dld 1.1.5.12 - C ko:K03777 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 D-lactate dehydrogenase, membrane binding
NBPHLDOP_00632 3.8e-39 - - - - - - - -
NBPHLDOP_00633 6.37e-82 - - - L ko:K07484 - ko00000 IS66 Orf2 like protein
NBPHLDOP_00634 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
NBPHLDOP_00635 7.23e-244 ysdE - - P - - - Citrate transporter
NBPHLDOP_00636 3.35e-84 - - - S - - - Protein of unknown function (DUF1093)
NBPHLDOP_00637 8.39e-21 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
NBPHLDOP_00638 7.48e-197 - - - M - - - Glycosyl hydrolases family 25
NBPHLDOP_00639 4.68e-189 - - - - - - - -
NBPHLDOP_00640 1.38e-274 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NBPHLDOP_00641 6.84e-186 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
NBPHLDOP_00642 8.58e-159 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NBPHLDOP_00643 6.3e-42 - - - - - - - -
NBPHLDOP_00644 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NBPHLDOP_00645 1.14e-151 - - - S - - - WxL domain surface cell wall-binding
NBPHLDOP_00646 2.1e-226 - - - S - - - Cell surface protein
NBPHLDOP_00647 1.78e-58 - - - - - - - -
NBPHLDOP_00648 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
NBPHLDOP_00649 1.66e-154 - - - S - - - WxL domain surface cell wall-binding
NBPHLDOP_00650 4.82e-78 - - - - - - - -
NBPHLDOP_00651 3.82e-142 - - - N - - - WxL domain surface cell wall-binding
NBPHLDOP_00652 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
NBPHLDOP_00653 4.19e-226 yicL - - EG - - - EamA-like transporter family
NBPHLDOP_00654 0.0 - - - - - - - -
NBPHLDOP_00655 3.03e-186 CcmA5 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NBPHLDOP_00656 4.07e-114 - - - S - - - ECF-type riboflavin transporter, S component
NBPHLDOP_00657 1.83e-192 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
NBPHLDOP_00658 7.88e-211 metF 1.5.1.20 - C ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Methylenetetrahydrofolate reductase
NBPHLDOP_00659 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NBPHLDOP_00660 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NBPHLDOP_00661 0.0 - - - V ko:K06147,ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NBPHLDOP_00662 3.34e-286 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
NBPHLDOP_00663 5.43e-167 treR - - K ko:K03486 - ko00000,ko03000 UTRA
NBPHLDOP_00664 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NBPHLDOP_00665 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NBPHLDOP_00666 2.25e-285 sstT - - U ko:K07862 - ko00000,ko02000 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NBPHLDOP_00667 0.0 - - - E ko:K03294 - ko00000 Amino Acid
NBPHLDOP_00668 3.94e-222 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 lactate/malate dehydrogenase, alpha/beta C-terminal domain
NBPHLDOP_00669 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NBPHLDOP_00670 3.08e-43 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
NBPHLDOP_00671 1.54e-91 - - - - - - - -
NBPHLDOP_00672 1.37e-99 - - - O - - - OsmC-like protein
NBPHLDOP_00673 0.0 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
NBPHLDOP_00674 2.73e-147 ylbE - - GM - - - NAD(P)H-binding
NBPHLDOP_00676 4.04e-204 - - - S - - - Aldo/keto reductase family
NBPHLDOP_00677 9.04e-317 yifK - - E ko:K03293 - ko00000 Amino acid permease
NBPHLDOP_00678 0.0 - - - S - - - Protein of unknown function (DUF3800)
NBPHLDOP_00679 0.0 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
NBPHLDOP_00680 2.72e-78 - - - S - - - Protein of unknown function (DUF3021)
NBPHLDOP_00681 2.95e-96 - - - K - - - LytTr DNA-binding domain
NBPHLDOP_00682 3.79e-192 - - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
NBPHLDOP_00683 6.73e-211 - - - V ko:K01990,ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NBPHLDOP_00684 6.41e-190 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NBPHLDOP_00685 3.43e-162 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
NBPHLDOP_00686 1.06e-69 ybjQ - - S - - - Belongs to the UPF0145 family
NBPHLDOP_00687 1.35e-208 - - - C - - - nadph quinone reductase
NBPHLDOP_00688 3.8e-316 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
NBPHLDOP_00689 2.05e-229 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
NBPHLDOP_00690 2.22e-154 yqgG - - S ko:K07507 - ko00000,ko02000 MgtC family
NBPHLDOP_00691 4.52e-160 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
NBPHLDOP_00692 0.000673 - 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Psort location CytoplasmicMembrane, score
NBPHLDOP_00693 1.62e-159 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 proteolysis
NBPHLDOP_00694 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
NBPHLDOP_00695 0.0 - - - L - - - ATPase domain of DNA mismatch repair MUTS family
NBPHLDOP_00696 3.79e-147 ung2 - - L - - - Uracil-DNA glycosylase
NBPHLDOP_00697 1.9e-170 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NBPHLDOP_00698 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
NBPHLDOP_00699 3.83e-86 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
NBPHLDOP_00700 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NBPHLDOP_00701 3.06e-182 - - - M - - - Glycosyltransferase like family 2
NBPHLDOP_00702 7.26e-208 lacT - - K ko:K02531 - ko00000,ko03000 PRD domain
NBPHLDOP_00703 0.0 lacE 2.7.1.207 - G ko:K02787,ko:K02788 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system, EIIC
NBPHLDOP_00704 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NBPHLDOP_00705 2.65e-67 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
NBPHLDOP_00706 2.83e-283 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NBPHLDOP_00707 4.24e-247 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NBPHLDOP_00708 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
NBPHLDOP_00709 1.02e-219 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NBPHLDOP_00710 8.63e-254 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
NBPHLDOP_00713 2.36e-111 - 2.7.1.204 - G ko:K20112 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBPHLDOP_00714 2.68e-67 - 2.7.1.204 - G ko:K20113 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NBPHLDOP_00715 0.0 gatC - - G ko:K20114 ko02060,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NBPHLDOP_00716 9.83e-37 - - - - - - - -
NBPHLDOP_00717 1.98e-163 - - - S - - - Domain of unknown function (DUF4867)
NBPHLDOP_00718 4.29e-226 lacC 2.7.1.144 - H ko:K00917 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
NBPHLDOP_00719 4.19e-239 lacD 4.1.2.40 - G ko:K01635 ko00052,ko01100,ko02024,map00052,map01100,map02024 ko00000,ko00001,ko01000 Belongs to the aldolase LacD family
NBPHLDOP_00720 4.53e-122 lacB 5.3.1.26 - G ko:K01819 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 Ribose/Galactose Isomerase
NBPHLDOP_00721 7.23e-96 lacA 5.3.1.26 - G ko:K01819 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 Ribose/Galactose Isomerase
NBPHLDOP_00722 4.13e-181 - - - K ko:K02530 - ko00000,ko03000 DeoR C terminal sensor domain
NBPHLDOP_00723 3.73e-150 - - - S - - - HAD hydrolase, family IA, variant
NBPHLDOP_00724 3.37e-272 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NBPHLDOP_00725 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
NBPHLDOP_00726 6.8e-21 - - - - - - - -
NBPHLDOP_00727 7.42e-112 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NBPHLDOP_00729 4.59e-272 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
NBPHLDOP_00730 1.91e-192 - - - I - - - alpha/beta hydrolase fold
NBPHLDOP_00731 1.06e-156 yrkL - - S - - - Flavodoxin-like fold
NBPHLDOP_00733 1.83e-113 - - - S - - - Short repeat of unknown function (DUF308)
NBPHLDOP_00734 1.92e-153 - - - S - - - Psort location Cytoplasmic, score
NBPHLDOP_00735 9.5e-199 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NBPHLDOP_00736 3.35e-252 - - - - - - - -
NBPHLDOP_00738 1.39e-149 - - - S ko:K07118 - ko00000 NAD(P)H-binding
NBPHLDOP_00739 0.0 bglB 3.2.1.21, 3.2.1.52 GH3 G ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501 ko00000,ko00001,ko00002,ko01000 hydrolase, family 3
NBPHLDOP_00740 6.45e-215 XK27_00670 - - S ko:K01989,ko:K05832 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
NBPHLDOP_00741 1.77e-214 XK27_00670 - - S ko:K01989,ko:K05832 - ko00000,ko00002,ko02000 ABC transporter
NBPHLDOP_00742 6.83e-208 WQ51_06230 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NBPHLDOP_00743 2.89e-181 - - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NBPHLDOP_00744 3.01e-225 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
NBPHLDOP_00745 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
NBPHLDOP_00746 8.07e-233 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyl transferase family 2
NBPHLDOP_00747 0.0 ykcB - - M - - - Dolichyl-phosphate-mannose-protein mannosyltransferase
NBPHLDOP_00748 1.53e-93 - - - S - - - GtrA-like protein
NBPHLDOP_00749 3.91e-159 ciaR - - K ko:K14983 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 cheY-homologous receiver domain
NBPHLDOP_00750 3.66e-310 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
NBPHLDOP_00751 9.85e-88 - - - S - - - Belongs to the HesB IscA family
NBPHLDOP_00752 0.0 - - - QT - - - PucR C-terminal helix-turn-helix domain
NBPHLDOP_00753 1.12e-208 - - - S - - - KR domain
NBPHLDOP_00754 1.71e-205 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
NBPHLDOP_00755 1.77e-158 ydgI - - C - - - Nitroreductase family
NBPHLDOP_00756 3.19e-263 lldD 1.13.12.4 - C ko:K00467 ko00620,map00620 ko00000,ko00001,ko01000 IMP dehydrogenase / GMP reductase domain
NBPHLDOP_00759 5.8e-248 - - - K - - - DNA-binding helix-turn-helix protein
NBPHLDOP_00760 1.17e-77 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
NBPHLDOP_00761 1.14e-63 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
NBPHLDOP_00762 4.91e-55 - - - - - - - -
NBPHLDOP_00763 2.1e-247 - 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NBPHLDOP_00764 2.78e-73 - - - - - - - -
NBPHLDOP_00765 1.79e-104 - - - - - - - -
NBPHLDOP_00766 5.77e-267 XK27_05220 - - S - - - AI-2E family transporter
NBPHLDOP_00767 1.58e-33 - - - - - - - -
NBPHLDOP_00768 9.86e-146 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NBPHLDOP_00769 4.2e-65 - - - - - - - -
NBPHLDOP_00770 5.96e-214 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
NBPHLDOP_00771 8.76e-82 ywrF - - S - - - Flavin reductase like domain
NBPHLDOP_00772 9.67e-91 - - - - - - - -
NBPHLDOP_00773 6.56e-131 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NBPHLDOP_00774 1.7e-81 yeaO - - S - - - Protein of unknown function, DUF488
NBPHLDOP_00775 2.2e-223 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
NBPHLDOP_00776 3.19e-206 mleR - - K - - - LysR family
NBPHLDOP_00777 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
NBPHLDOP_00778 3.58e-217 mleP - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
NBPHLDOP_00779 8.23e-117 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NBPHLDOP_00780 2.28e-113 - - - C - - - FMN binding
NBPHLDOP_00781 1.32e-223 - - - K ko:K20373,ko:K20374 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix XRE-family like proteins
NBPHLDOP_00782 0.0 - - - V - - - ABC transporter transmembrane region
NBPHLDOP_00783 0.0 pepF - - E - - - Oligopeptidase F
NBPHLDOP_00784 9.47e-79 - - - - - - - -
NBPHLDOP_00785 3.81e-170 - - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NBPHLDOP_00786 4.06e-107 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
NBPHLDOP_00787 0.0 yfgQ - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
NBPHLDOP_00788 6.63e-232 - 3.4.11.5 - I ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 carboxylic ester hydrolase activity
NBPHLDOP_00789 1.69e-58 - - - - - - - -
NBPHLDOP_00790 4.89e-122 - - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NBPHLDOP_00791 1.38e-256 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NBPHLDOP_00792 9.07e-158 XK27_05175 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
NBPHLDOP_00793 2.24e-101 - - - K - - - Transcriptional regulator
NBPHLDOP_00794 2.4e-231 ybcH - - D ko:K06889 - ko00000 Alpha beta
NBPHLDOP_00795 3.28e-110 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
NBPHLDOP_00796 4.36e-200 dkgB - - S - - - reductase
NBPHLDOP_00797 4.98e-203 - - - - - - - -
NBPHLDOP_00798 6.16e-199 - - - S - - - Alpha beta hydrolase
NBPHLDOP_00799 1.29e-150 yviA - - S - - - Protein of unknown function (DUF421)
NBPHLDOP_00800 4.49e-97 - - - S - - - Protein of unknown function (DUF3290)
NBPHLDOP_00801 4.17e-284 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
NBPHLDOP_00802 1.69e-112 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NBPHLDOP_00803 1.3e-136 yjbF - - S - - - SNARE associated Golgi protein
NBPHLDOP_00804 2.95e-133 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NBPHLDOP_00805 1.59e-241 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NBPHLDOP_00806 1.11e-264 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NBPHLDOP_00807 1.71e-289 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NBPHLDOP_00808 4.49e-88 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
NBPHLDOP_00809 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
NBPHLDOP_00810 2.06e-150 mntR - - K ko:K03709 - ko00000,ko03000 Helix-turn-helix diphteria tox regulatory element
NBPHLDOP_00811 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NBPHLDOP_00812 1.25e-264 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NBPHLDOP_00813 1.13e-307 ytoI - - K - - - DRTGG domain
NBPHLDOP_00814 3.03e-229 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
NBPHLDOP_00815 0.0 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NBPHLDOP_00816 2.29e-225 - - - - - - - -
NBPHLDOP_00817 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NBPHLDOP_00819 4.89e-58 yrzL - - S - - - Belongs to the UPF0297 family
NBPHLDOP_00820 2.67e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NBPHLDOP_00821 1.3e-69 yrzB - - S - - - Belongs to the UPF0473 family
NBPHLDOP_00822 2.84e-48 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NBPHLDOP_00823 1.89e-119 cvpA - - S - - - Colicin V production protein
NBPHLDOP_00824 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NBPHLDOP_00825 3.64e-70 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NBPHLDOP_00826 1.04e-27 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
NBPHLDOP_00827 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NBPHLDOP_00828 9.86e-304 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
NBPHLDOP_00829 6.97e-49 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NBPHLDOP_00830 2.04e-312 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NBPHLDOP_00831 2.02e-112 yslB - - S - - - Protein of unknown function (DUF2507)
NBPHLDOP_00832 0.0 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NBPHLDOP_00833 1.15e-125 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
NBPHLDOP_00834 1.9e-175 gla - - U ko:K02440 - ko00000,ko02000 Major intrinsic protein
NBPHLDOP_00835 6.56e-112 ykuL - - S - - - CBS domain
NBPHLDOP_00836 3.55e-203 - - - S ko:K08974 - ko00000 Domain of unknown function (DUF368)
NBPHLDOP_00837 6.86e-198 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
NBPHLDOP_00838 1.49e-46 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NBPHLDOP_00839 1.69e-114 ytxH - - S - - - YtxH-like protein
NBPHLDOP_00840 7.49e-117 yrxA - - S ko:K07105 - ko00000 3H domain
NBPHLDOP_00841 3.25e-276 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
NBPHLDOP_00842 3.03e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
NBPHLDOP_00843 3.35e-247 - - - L ko:K07482 - ko00000 Helix-turn-helix domain
NBPHLDOP_00844 0.0 pbp1B 2.4.1.129 GT51 M ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin binding protein transpeptidase domain
NBPHLDOP_00845 1.78e-240 pbp1B 2.4.1.129 GT51 M ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Transglycosylase
NBPHLDOP_00846 1.06e-163 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
NBPHLDOP_00847 5.87e-177 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NBPHLDOP_00848 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
NBPHLDOP_00849 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
NBPHLDOP_00850 5.84e-51 - - - - - - - -
NBPHLDOP_00851 1.46e-241 yibE - - S - - - overlaps another CDS with the same product name
NBPHLDOP_00852 5.42e-150 yibF - - S - - - overlaps another CDS with the same product name
NBPHLDOP_00853 2.58e-148 - - - S - - - Calcineurin-like phosphoesterase
NBPHLDOP_00854 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NBPHLDOP_00855 6.42e-154 yutD - - S - - - Protein of unknown function (DUF1027)
NBPHLDOP_00856 1.34e-186 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NBPHLDOP_00857 2.62e-145 - - - S - - - Protein of unknown function (DUF1461)
NBPHLDOP_00858 1.83e-150 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
NBPHLDOP_00859 2.26e-115 pgpA 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Phosphatidylglycerophosphatase A
NBPHLDOP_00860 2.84e-239 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
NBPHLDOP_00861 4.42e-142 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NBPHLDOP_00862 1.17e-82 yugI - - J ko:K07570 - ko00000 general stress protein
NBPHLDOP_00863 5.19e-90 - - - S - - - COG NOG38524 non supervised orthologous group
NBPHLDOP_00890 3.8e-39 - - - - - - - -
NBPHLDOP_00891 6.37e-82 - - - L ko:K07484 - ko00000 IS66 Orf2 like protein
NBPHLDOP_00892 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
NBPHLDOP_00893 8.3e-123 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 DNA-templated transcription, initiation
NBPHLDOP_00894 0.0 ybeC - - E - - - amino acid
NBPHLDOP_00896 1.09e-294 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
NBPHLDOP_00897 1.13e-252 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
NBPHLDOP_00898 1.58e-220 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NBPHLDOP_00900 1.63e-279 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NBPHLDOP_00901 1.52e-57 ykuJ - - S - - - Protein of unknown function (DUF1797)
NBPHLDOP_00902 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NBPHLDOP_00903 1.04e-103 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
NBPHLDOP_00904 5.19e-90 - - - S - - - COG NOG38524 non supervised orthologous group
NBPHLDOP_00909 3.98e-91 - - - - - - - -
NBPHLDOP_00910 7.89e-268 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NBPHLDOP_00911 0.0 mdr - - EGP - - - Major Facilitator
NBPHLDOP_00912 2.92e-108 - - - K - - - MerR HTH family regulatory protein
NBPHLDOP_00913 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
NBPHLDOP_00914 6.46e-156 - - - S - - - Domain of unknown function (DUF4811)
NBPHLDOP_00915 1.89e-157 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
NBPHLDOP_00916 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
NBPHLDOP_00917 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
NBPHLDOP_00918 2.3e-167 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NBPHLDOP_00919 9.15e-45 yhcC - - S ko:K07069 - ko00000 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
NBPHLDOP_00920 3.37e-183 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NBPHLDOP_00921 4.57e-124 - - - F - - - NUDIX domain
NBPHLDOP_00923 6.11e-278 int3 - - L - - - Belongs to the 'phage' integrase family
NBPHLDOP_00924 1.64e-263 - - - V - - - Abi-like protein
NBPHLDOP_00925 1.68e-94 - - - - - - - -
NBPHLDOP_00926 4.14e-15 - - - - - - - -
NBPHLDOP_00927 1.09e-23 - - - - - - - -
NBPHLDOP_00929 0.000185 - - - K - - - sequence-specific DNA binding
NBPHLDOP_00931 1.01e-163 - - - K - - - Transcriptional regulator
NBPHLDOP_00933 3.74e-52 - - - S - - - Domain of unknown function (DUF771)
NBPHLDOP_00936 4.78e-217 yqaJ - - L - - - YqaJ-like viral recombinase domain
NBPHLDOP_00938 1.65e-210 recT - - L ko:K07455 - ko00000,ko03400 RecT family
NBPHLDOP_00939 2.43e-49 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
NBPHLDOP_00940 1.64e-178 - - - L - - - Transcriptional regulator
NBPHLDOP_00941 1.57e-197 pi346 - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
NBPHLDOP_00943 2.14e-58 - - - - - - - -
NBPHLDOP_00945 7.92e-135 - - - S - - - HNH endonuclease
NBPHLDOP_00946 2.31e-97 rusA - - L - - - Endodeoxyribonuclease RusA
NBPHLDOP_00947 2.83e-53 - - - - - - - -
NBPHLDOP_00949 1.93e-105 - - - - - - - -
NBPHLDOP_00950 1.57e-91 - - - V - - - HNH endonuclease
NBPHLDOP_00951 1.23e-81 - - - - - - - -
NBPHLDOP_00952 0.0 - - - S - - - overlaps another CDS with the same product name
NBPHLDOP_00953 1.45e-299 - - - S - - - Phage portal protein
NBPHLDOP_00954 2.39e-164 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
NBPHLDOP_00955 8.24e-289 - - - S - - - Phage capsid family
NBPHLDOP_00957 9.08e-71 - - - - - - - -
NBPHLDOP_00958 3.92e-76 - - - S - - - Phage head-tail joining protein
NBPHLDOP_00959 1.28e-75 - - - - - - - -
NBPHLDOP_00960 3.16e-89 - - - - - - - -
NBPHLDOP_00961 3.43e-154 - - - - - - - -
NBPHLDOP_00962 1.73e-81 - - - - - - - -
NBPHLDOP_00963 0.0 - - - D - - - Phage tail tape measure protein
NBPHLDOP_00964 1.5e-165 - - - S - - - phage tail
NBPHLDOP_00965 0.0 - - - LM - - - gp58-like protein
NBPHLDOP_00966 2.91e-94 - - - - - - - -
NBPHLDOP_00967 2.21e-51 - - - - - - - -
NBPHLDOP_00968 4.88e-59 - - - - - - - -
NBPHLDOP_00969 2.93e-75 hol - - S - - - Bacteriophage holin
NBPHLDOP_00971 3.23e-252 - - - M - - - Bacteriophage peptidoglycan hydrolase
NBPHLDOP_00972 0.0 tagE2 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NBPHLDOP_00973 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NBPHLDOP_00974 9.78e-112 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
NBPHLDOP_00977 7.73e-299 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
NBPHLDOP_00978 2.27e-247 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
NBPHLDOP_00979 0.0 cpdA - - S - - - Calcineurin-like phosphoesterase
NBPHLDOP_00980 5.05e-52 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
NBPHLDOP_00981 1.12e-311 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
NBPHLDOP_00982 4.22e-273 coiA - - S ko:K06198 - ko00000 Competence protein
NBPHLDOP_00983 1.15e-150 yjbH - - Q - - - Thioredoxin
NBPHLDOP_00984 1.79e-138 - - - S - - - CYTH
NBPHLDOP_00985 1.19e-158 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
NBPHLDOP_00986 1.05e-193 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NBPHLDOP_00987 1.22e-219 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NBPHLDOP_00988 4.86e-259 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NBPHLDOP_00989 2.24e-148 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
NBPHLDOP_00990 2.39e-187 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NBPHLDOP_00991 2.39e-256 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
NBPHLDOP_00992 3.87e-80 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
NBPHLDOP_00993 4.12e-56 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NBPHLDOP_00994 2.45e-245 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NBPHLDOP_00995 1.94e-219 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
NBPHLDOP_00996 1.46e-201 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
NBPHLDOP_00997 3.21e-125 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NBPHLDOP_00998 4.04e-94 - - - S - - - Protein of unknown function (DUF1149)
NBPHLDOP_00999 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NBPHLDOP_01000 3.28e-296 ymfF - - S - - - Peptidase M16 inactive domain protein
NBPHLDOP_01001 3.94e-309 ymfH - - S - - - Peptidase M16
NBPHLDOP_01002 3.01e-166 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
NBPHLDOP_01003 1.15e-169 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
NBPHLDOP_01004 3.46e-136 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NBPHLDOP_01005 3.67e-294 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
NBPHLDOP_01006 5.55e-245 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NBPHLDOP_01007 7.95e-317 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
NBPHLDOP_01008 5.06e-152 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
NBPHLDOP_01009 1.47e-304 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
NBPHLDOP_01010 4.32e-104 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
NBPHLDOP_01011 3.24e-126 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NBPHLDOP_01012 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NBPHLDOP_01013 8.69e-239 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NBPHLDOP_01014 1.56e-161 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 ABC transporter
NBPHLDOP_01015 1.9e-200 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NBPHLDOP_01016 7.77e-259 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
NBPHLDOP_01017 1.83e-168 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NBPHLDOP_01018 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NBPHLDOP_01019 4.5e-199 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
NBPHLDOP_01020 4.48e-205 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
NBPHLDOP_01021 5.26e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
NBPHLDOP_01022 1.57e-192 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NBPHLDOP_01023 2.49e-180 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NBPHLDOP_01024 3.82e-156 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
NBPHLDOP_01025 0.0 yvlB - - S - - - Putative adhesin
NBPHLDOP_01026 5.23e-50 - - - - - - - -
NBPHLDOP_01027 3.07e-50 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
NBPHLDOP_01028 8.27e-223 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NBPHLDOP_01029 7.94e-202 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NBPHLDOP_01030 6.29e-250 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
NBPHLDOP_01031 3.41e-230 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NBPHLDOP_01032 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NBPHLDOP_01033 1.51e-148 - - - T - - - Transcriptional regulatory protein, C terminal
NBPHLDOP_01034 4.14e-225 - - - T - - - His Kinase A (phosphoacceptor) domain
NBPHLDOP_01035 8.85e-47 - - - V ko:K02003 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
NBPHLDOP_01036 2.03e-96 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NBPHLDOP_01037 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NBPHLDOP_01038 1.99e-153 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
NBPHLDOP_01039 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NBPHLDOP_01040 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NBPHLDOP_01041 2.56e-111 - - - S - - - Short repeat of unknown function (DUF308)
NBPHLDOP_01042 8.53e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
NBPHLDOP_01043 2.99e-248 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
NBPHLDOP_01044 2.88e-221 whiA - - K ko:K09762 - ko00000 May be required for sporulation
NBPHLDOP_01045 7.84e-106 ohrR - - K ko:K18906 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
NBPHLDOP_01046 5.97e-132 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NBPHLDOP_01048 8.72e-280 int3 - - L - - - Belongs to the 'phage' integrase family
NBPHLDOP_01049 2.5e-184 - - - - - - - -
NBPHLDOP_01050 9.85e-49 - - - - - - - -
NBPHLDOP_01051 5.99e-154 - - - P ko:K10716 - ko00000,ko02000 Ion transport protein
NBPHLDOP_01052 3.75e-98 - - - E - - - Zn peptidase
NBPHLDOP_01053 1.9e-72 - - - K - - - Helix-turn-helix XRE-family like proteins
NBPHLDOP_01055 1.39e-183 - - - K - - - ORF6N domain
NBPHLDOP_01056 4.68e-77 - - - S - - - Domain of unknown function (DUF771)
NBPHLDOP_01062 6.5e-109 - - - S - - - Siphovirus Gp157
NBPHLDOP_01064 0.0 - - - L - - - Helicase C-terminal domain protein
NBPHLDOP_01065 1.89e-171 - - - L - - - AAA domain
NBPHLDOP_01066 4.92e-120 - - - - - - - -
NBPHLDOP_01067 6.41e-193 - - - L - - - Bifunctional DNA primase/polymerase, N-terminal
NBPHLDOP_01068 1.59e-302 - - - S ko:K06919 - ko00000 Virulence-associated protein E
NBPHLDOP_01069 1.66e-71 - - - S - - - VRR_NUC
NBPHLDOP_01070 5.25e-59 - - - - - - - -
NBPHLDOP_01072 7.3e-137 - - - S - - - HNH endonuclease
NBPHLDOP_01074 2.86e-93 - - - S - - - Transcriptional regulator, RinA family
NBPHLDOP_01075 2.61e-92 - - - V - - - HNH endonuclease
NBPHLDOP_01076 1.73e-83 - - - - - - - -
NBPHLDOP_01077 0.0 - - - S - - - overlaps another CDS with the same product name
NBPHLDOP_01078 3.57e-300 - - - S - - - Phage portal protein
NBPHLDOP_01079 1.68e-164 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
NBPHLDOP_01080 1.66e-288 - - - S - - - Phage capsid family
NBPHLDOP_01082 9.08e-71 - - - - - - - -
NBPHLDOP_01083 3.92e-76 - - - S - - - Phage head-tail joining protein
NBPHLDOP_01084 1.28e-75 - - - - - - - -
NBPHLDOP_01085 9.07e-89 - - - - - - - -
NBPHLDOP_01086 2.82e-153 - - - - - - - -
NBPHLDOP_01087 1.73e-81 - - - - - - - -
NBPHLDOP_01088 0.0 - - - D - - - Phage tail tape measure protein
NBPHLDOP_01089 4.31e-165 - - - S - - - phage tail
NBPHLDOP_01090 0.0 - - - LM - - - gp58-like protein
NBPHLDOP_01091 2.91e-94 - - - - - - - -
NBPHLDOP_01092 1.62e-53 - - - - - - - -
NBPHLDOP_01093 5.45e-86 - - - - - - - -
NBPHLDOP_01095 6.86e-92 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
NBPHLDOP_01096 1.51e-261 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NBPHLDOP_01098 5.52e-241 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
NBPHLDOP_01099 2.1e-247 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NBPHLDOP_01100 2.16e-282 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
NBPHLDOP_01101 2.81e-180 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NBPHLDOP_01102 2.11e-315 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NBPHLDOP_01103 6.34e-294 mdt(A) - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
NBPHLDOP_01104 1.33e-63 - - - - - - - -
NBPHLDOP_01105 0.0 eriC - - P ko:K03281 - ko00000 chloride
NBPHLDOP_01106 5.04e-43 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
NBPHLDOP_01107 2.82e-181 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
NBPHLDOP_01108 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NBPHLDOP_01109 4.47e-108 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NBPHLDOP_01110 2.3e-228 yvdE - - K - - - helix_turn _helix lactose operon repressor
NBPHLDOP_01111 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
NBPHLDOP_01112 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NBPHLDOP_01113 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
NBPHLDOP_01114 1.8e-157 - 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NBPHLDOP_01115 2.35e-270 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NBPHLDOP_01116 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
NBPHLDOP_01117 1.96e-292 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NBPHLDOP_01118 0.0 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NBPHLDOP_01119 4.66e-196 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NBPHLDOP_01120 1.34e-22 - - - - - - - -
NBPHLDOP_01121 2.46e-36 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
NBPHLDOP_01122 2.99e-310 YSH1 - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Metallo-beta-lactamase superfamily
NBPHLDOP_01123 4.3e-312 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NBPHLDOP_01124 3.82e-189 malF - - G ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NBPHLDOP_01125 1.42e-212 - - - P ko:K02025 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
NBPHLDOP_01126 3.08e-248 malK - - P ko:K10112,ko:K17240 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
NBPHLDOP_01127 3.63e-136 - - - K ko:K06977 - ko00000 Acetyltransferase (GNAT) domain
NBPHLDOP_01128 7.57e-119 - - - - - - - -
NBPHLDOP_01129 4e-203 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
NBPHLDOP_01130 1.45e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NBPHLDOP_01131 5.22e-229 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
NBPHLDOP_01132 1.35e-107 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
NBPHLDOP_01134 1.6e-214 ysdB - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NBPHLDOP_01135 2.2e-276 ysdA - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NBPHLDOP_01136 1.97e-129 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NBPHLDOP_01137 8.14e-194 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
NBPHLDOP_01138 4.74e-213 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
NBPHLDOP_01139 0.0 yvgP - - P ko:K03316 - ko00000 Sodium proton antiporter
NBPHLDOP_01140 1.97e-124 - - - K - - - Cupin domain
NBPHLDOP_01141 9.1e-263 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NBPHLDOP_01142 2.49e-190 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NBPHLDOP_01143 7.08e-188 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NBPHLDOP_01144 8.49e-267 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NBPHLDOP_01146 0.0 pacL - - P - - - Cation transporter/ATPase, N-terminus
NBPHLDOP_01147 1.82e-144 - - - K - - - Transcriptional regulator
NBPHLDOP_01148 1.69e-243 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NBPHLDOP_01149 1.09e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NBPHLDOP_01150 3.82e-195 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NBPHLDOP_01151 1.36e-217 ybbR - - S - - - YbbR-like protein
NBPHLDOP_01152 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NBPHLDOP_01153 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NBPHLDOP_01155 0.0 pepF2 - - E - - - Oligopeptidase F
NBPHLDOP_01156 3.35e-106 - - - S - - - VanZ like family
NBPHLDOP_01157 5.85e-169 yebC - - K - - - Transcriptional regulatory protein
NBPHLDOP_01158 1.02e-196 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
NBPHLDOP_01159 7.91e-219 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
NBPHLDOP_01160 1e-35 - - - - ko:K02245 - ko00000,ko00002,ko02044 -
NBPHLDOP_01162 8.98e-30 - - - - - - - -
NBPHLDOP_01163 2.01e-24 - - - - ko:K02248 - ko00000,ko00002,ko02044 -
NBPHLDOP_01165 3.73e-239 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
NBPHLDOP_01166 2.1e-81 - - - - - - - -
NBPHLDOP_01167 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
NBPHLDOP_01168 7.51e-191 arbV - - I - - - Phosphate acyltransferases
NBPHLDOP_01169 2.02e-212 arbx - - M - - - Glycosyl transferase family 8
NBPHLDOP_01170 2.41e-235 arbY - - M - - - family 8
NBPHLDOP_01171 9.24e-214 arbZ - - I - - - Phosphate acyltransferases
NBPHLDOP_01172 0.0 rafA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
NBPHLDOP_01175 6.55e-93 - - - S - - - SdpI/YhfL protein family
NBPHLDOP_01176 3.55e-174 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
NBPHLDOP_01177 0.0 yclK - - T - - - Histidine kinase
NBPHLDOP_01178 5.76e-22 - - - S - - - acetyltransferase
NBPHLDOP_01179 2.45e-75 - - - S - - - acetyltransferase
NBPHLDOP_01180 1.16e-19 - - - - - - - -
NBPHLDOP_01181 1.27e-94 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
NBPHLDOP_01182 1.53e-88 - - - - - - - -
NBPHLDOP_01183 8.56e-74 - - - - - - - -
NBPHLDOP_01184 0.0 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
NBPHLDOP_01186 3.92e-270 tcaA - - S ko:K21463 - ko00000 response to antibiotic
NBPHLDOP_01187 1.28e-182 - 3.1.1.5 - E ko:K10804 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 GDSL-like Lipase/Acylhydrolase
NBPHLDOP_01188 5.65e-46 - - - S - - - Bacterial protein of unknown function (DUF898)
NBPHLDOP_01189 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
NBPHLDOP_01190 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NBPHLDOP_01191 3e-271 camS - - S - - - sex pheromone
NBPHLDOP_01192 3.61e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NBPHLDOP_01193 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NBPHLDOP_01194 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NBPHLDOP_01195 4.97e-248 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
NBPHLDOP_01196 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NBPHLDOP_01197 7.92e-282 yttB - - EGP - - - Major Facilitator
NBPHLDOP_01198 6.2e-191 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NBPHLDOP_01199 8.52e-211 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
NBPHLDOP_01200 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
NBPHLDOP_01201 0.0 - - - EGP - - - Major Facilitator
NBPHLDOP_01202 4.37e-107 - - - K - - - Acetyltransferase (GNAT) family
NBPHLDOP_01203 2.87e-213 yitS - - S - - - Uncharacterised protein, DegV family COG1307
NBPHLDOP_01204 3.38e-166 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
NBPHLDOP_01205 4.3e-40 - - - - - - - -
NBPHLDOP_01206 6.15e-181 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
NBPHLDOP_01207 9.39e-80 - - - S - - - Protein of unknown function (DUF1093)
NBPHLDOP_01208 1.9e-79 - - - S - - - Domain of unknown function (DUF4828)
NBPHLDOP_01209 2.69e-227 mocA - - S - - - Oxidoreductase
NBPHLDOP_01210 1.79e-304 yfmL - - L - - - DEAD DEAH box helicase
NBPHLDOP_01211 2.76e-74 chbA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system
NBPHLDOP_01212 4.49e-93 - - - S - - - Domain of unknown function (DUF3284)
NBPHLDOP_01214 6.45e-06 - - - - - - - -
NBPHLDOP_01215 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
NBPHLDOP_01216 3.61e-309 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 Thermophilic metalloprotease (M29)
NBPHLDOP_01217 2.96e-144 - - - K - - - Bacterial regulatory proteins, tetR family
NBPHLDOP_01218 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
NBPHLDOP_01219 9.73e-230 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
NBPHLDOP_01220 1.24e-103 fld - - C ko:K03839 - ko00000 Flavodoxin
NBPHLDOP_01221 4.05e-205 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
NBPHLDOP_01222 3.86e-261 - - - M - - - Glycosyltransferase like family 2
NBPHLDOP_01224 5.92e-20 - - - - - - - -
NBPHLDOP_01225 1.09e-253 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
NBPHLDOP_01226 4.58e-217 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NBPHLDOP_01227 2.46e-215 - - - L ko:K07497 - ko00000 hmm pf00665
NBPHLDOP_01228 2.5e-174 - - - L - - - Helix-turn-helix domain
NBPHLDOP_01231 2.44e-210 - 4.2.1.46 - GM ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Male sterility protein
NBPHLDOP_01232 1.72e-242 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
NBPHLDOP_01233 4.89e-186 - - - S - - - Cell surface protein
NBPHLDOP_01235 0.0 - - - N - - - domain, Protein
NBPHLDOP_01236 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NBPHLDOP_01237 0.0 bglH - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NBPHLDOP_01238 7.44e-193 licT2 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
NBPHLDOP_01239 0.0 - - - S - - - Bacterial membrane protein YfhO
NBPHLDOP_01240 0.0 - - - S - - - Psort location CytoplasmicMembrane, score
NBPHLDOP_01241 1.48e-220 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
NBPHLDOP_01242 3.64e-134 - - - - - - - -
NBPHLDOP_01243 3.61e-218 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
NBPHLDOP_01244 6.22e-43 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
NBPHLDOP_01245 4.8e-109 yvbK - - K - - - GNAT family
NBPHLDOP_01246 1.45e-149 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
NBPHLDOP_01247 2.27e-132 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NBPHLDOP_01248 6.23e-303 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
NBPHLDOP_01249 1.15e-261 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NBPHLDOP_01250 1.16e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NBPHLDOP_01251 3.79e-136 - - - - - - - -
NBPHLDOP_01252 6.04e-137 - - - - - - - -
NBPHLDOP_01253 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NBPHLDOP_01254 7.87e-144 vanZ - - V - - - VanZ like family
NBPHLDOP_01255 4.66e-196 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
NBPHLDOP_01256 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
NBPHLDOP_01257 8.38e-186 - - - S - - - Domain of unknown function DUF1829
NBPHLDOP_01258 2.12e-63 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
NBPHLDOP_01260 1.69e-197 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
NBPHLDOP_01261 2.7e-103 - - - S - - - Pfam Transposase IS66
NBPHLDOP_01262 1.72e-242 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
NBPHLDOP_01263 6.79e-295 - - GT2,GT4 M ko:K20444 - ko00000,ko01000,ko01005,ko02000 Glycosyl transferases group 1
NBPHLDOP_01264 1.09e-220 ysjB - - S ko:K03810 - ko00000 Oxidoreductase family, NAD-binding Rossmann fold
NBPHLDOP_01265 9.82e-111 guaD - - FJ - - - MafB19-like deaminase
NBPHLDOP_01267 5.18e-104 tspO - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 TspO/MBR family
NBPHLDOP_01268 1.53e-19 - - - - - - - -
NBPHLDOP_01269 9.73e-275 yttB - - EGP - - - Major Facilitator
NBPHLDOP_01270 4.36e-136 - - - S - - - Protein of unknown function (DUF1211)
NBPHLDOP_01271 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NBPHLDOP_01274 2.58e-166 pgm7 - - G - - - Phosphoglycerate mutase family
NBPHLDOP_01275 6.41e-155 - - - K - - - Bacterial regulatory proteins, tetR family
NBPHLDOP_01276 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
NBPHLDOP_01277 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
NBPHLDOP_01278 1.29e-181 - - - S - - - NADPH-dependent FMN reductase
NBPHLDOP_01279 8.21e-212 catE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
NBPHLDOP_01280 9.13e-252 ampC - - V - - - Beta-lactamase
NBPHLDOP_01281 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
NBPHLDOP_01282 7.61e-144 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
NBPHLDOP_01283 8.62e-252 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NBPHLDOP_01284 2.32e-196 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NBPHLDOP_01285 1.2e-238 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NBPHLDOP_01286 1.57e-298 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NBPHLDOP_01287 3.05e-145 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NBPHLDOP_01288 1.23e-162 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
NBPHLDOP_01289 2.57e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NBPHLDOP_01290 1.13e-83 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NBPHLDOP_01291 3.37e-117 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NBPHLDOP_01292 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NBPHLDOP_01293 1.92e-211 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NBPHLDOP_01294 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NBPHLDOP_01295 1.88e-91 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
NBPHLDOP_01296 8.38e-42 - - - S - - - Protein of unknown function (DUF1146)
NBPHLDOP_01297 4.12e-228 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
NBPHLDOP_01298 1.37e-26 - - - S - - - DNA-directed RNA polymerase subunit beta
NBPHLDOP_01299 1.14e-72 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
NBPHLDOP_01300 8.37e-42 - - - S - - - Protein of unknown function (DUF2969)
NBPHLDOP_01301 1.41e-285 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
NBPHLDOP_01302 4.19e-65 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
NBPHLDOP_01303 3.19e-284 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
NBPHLDOP_01304 1.88e-186 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NBPHLDOP_01305 8.04e-192 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NBPHLDOP_01306 2.09e-243 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NBPHLDOP_01307 9.25e-150 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NBPHLDOP_01308 4.15e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
NBPHLDOP_01309 4.72e-244 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
NBPHLDOP_01310 6.46e-285 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NBPHLDOP_01311 1.72e-103 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
NBPHLDOP_01312 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
NBPHLDOP_01313 4.73e-31 - - - - - - - -
NBPHLDOP_01314 9.85e-88 - - - S - - - Protein of unknown function (DUF1694)
NBPHLDOP_01315 3.03e-231 - - - S - - - Protein of unknown function (DUF2785)
NBPHLDOP_01316 1.29e-150 yhfA - - S - - - HAD hydrolase, family IA, variant 3
NBPHLDOP_01317 2.7e-200 - - - K - - - Helix-turn-helix XRE-family like proteins
NBPHLDOP_01318 2.86e-108 uspA - - T - - - universal stress protein
NBPHLDOP_01319 9.94e-54 - - - - - - - -
NBPHLDOP_01321 1.66e-306 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
NBPHLDOP_01322 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
NBPHLDOP_01323 1.17e-100 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
NBPHLDOP_01324 5.99e-143 yktB - - S - - - Belongs to the UPF0637 family
NBPHLDOP_01325 1.02e-158 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
NBPHLDOP_01326 1.61e-193 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NBPHLDOP_01327 4.65e-158 - - - G - - - alpha-ribazole phosphatase activity
NBPHLDOP_01328 7.23e-200 mrsA1 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NBPHLDOP_01329 1.81e-222 - - - IQ - - - NAD dependent epimerase/dehydratase family
NBPHLDOP_01330 2.93e-178 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
NBPHLDOP_01331 2.05e-173 - - - F - - - deoxynucleoside kinase
NBPHLDOP_01332 4.04e-203 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphatase and related hydrolases of the PHP family
NBPHLDOP_01333 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NBPHLDOP_01334 1.24e-202 - - - T - - - GHKL domain
NBPHLDOP_01335 2.69e-156 - - - T - - - Transcriptional regulatory protein, C terminal
NBPHLDOP_01336 1.17e-217 bcrA - - V ko:K01990,ko:K19309 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NBPHLDOP_01337 4.43e-143 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NBPHLDOP_01338 1.46e-207 - - - K - - - Transcriptional regulator
NBPHLDOP_01339 9.46e-103 yphH - - S - - - Cupin domain
NBPHLDOP_01340 1.07e-72 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
NBPHLDOP_01341 2.72e-149 - - - GM - - - NAD(P)H-binding
NBPHLDOP_01342 1.94e-54 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NBPHLDOP_01343 4.73e-158 gst 2.5.1.18 - O ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 ko00000,ko00001,ko01000,ko02000 Glutathione S-transferase, C-terminal domain
NBPHLDOP_01344 2.07e-149 - - - K - - - Psort location Cytoplasmic, score
NBPHLDOP_01345 7.95e-219 - - - K - - - Acetyltransferase (GNAT) domain
NBPHLDOP_01346 3.03e-115 - - - K - - - Acetyltransferase (GNAT) domain
NBPHLDOP_01347 5.91e-199 degV - - S - - - Uncharacterised protein, DegV family COG1307
NBPHLDOP_01348 2.07e-135 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
NBPHLDOP_01349 2.43e-264 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NBPHLDOP_01350 1.17e-169 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NBPHLDOP_01351 4.87e-203 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NBPHLDOP_01352 1.07e-281 - - - - - - - -
NBPHLDOP_01353 6.49e-90 - - - K - - - helix_turn_helix, mercury resistance
NBPHLDOP_01354 4.87e-66 - - - S - - - Protein of unknown function (DUF2568)
NBPHLDOP_01355 4.9e-151 - - - S - - - Protein of unknown function C-terminus (DUF2399)
NBPHLDOP_01356 5.07e-157 - - - K - - - Acetyltransferase (GNAT) domain
NBPHLDOP_01357 1.23e-57 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
NBPHLDOP_01358 8.76e-63 - - - S - - - ParE toxin of type II toxin-antitoxin system, parDE
NBPHLDOP_01360 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
NBPHLDOP_01361 4.82e-226 - - - L - - - Transposase and inactivated derivatives, IS30 family
NBPHLDOP_01363 3.6e-42 - - - L ko:K07481 - ko00000 Transposase
NBPHLDOP_01364 1.29e-151 - - - L - - - Transposase
NBPHLDOP_01365 2.47e-125 - - - L - - - Transposase
NBPHLDOP_01366 4.95e-134 - - - S ko:K06915 - ko00000 AAA-like domain
NBPHLDOP_01367 2.47e-251 - - - S ko:K06915 - ko00000 helicase activity
NBPHLDOP_01368 1.1e-227 - - - S - - - SIR2-like domain
NBPHLDOP_01370 0.0 - - - - - - - -
NBPHLDOP_01371 7.29e-06 - - - - - - - -
NBPHLDOP_01372 1.55e-10 - - - L - - - Transposase IS66 family
NBPHLDOP_01373 1.6e-10 - - - L ko:K07484 - ko00000 PFAM transposase IS66
NBPHLDOP_01374 5.31e-143 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NBPHLDOP_01375 1.23e-111 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
NBPHLDOP_01376 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NBPHLDOP_01377 6.1e-272 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
NBPHLDOP_01378 6.03e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NBPHLDOP_01379 1.24e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NBPHLDOP_01380 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NBPHLDOP_01381 3.79e-309 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NBPHLDOP_01382 1.98e-148 - - - S - - - Haloacid dehalogenase-like hydrolase
NBPHLDOP_01383 1.97e-152 radC - - L ko:K03630 - ko00000 DNA repair protein
NBPHLDOP_01384 4.82e-229 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
NBPHLDOP_01385 3.25e-192 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
NBPHLDOP_01386 1.23e-112 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
NBPHLDOP_01387 2.31e-149 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NBPHLDOP_01388 8.63e-182 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
NBPHLDOP_01389 4.79e-142 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
NBPHLDOP_01390 3.29e-146 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter
NBPHLDOP_01391 2.32e-193 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
NBPHLDOP_01392 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NBPHLDOP_01393 7.11e-60 - - - - - - - -
NBPHLDOP_01394 1.61e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
NBPHLDOP_01395 1.66e-219 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NBPHLDOP_01396 1.6e-68 ftsL - - D - - - cell division protein FtsL
NBPHLDOP_01397 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NBPHLDOP_01398 1.33e-230 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NBPHLDOP_01399 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NBPHLDOP_01400 4e-259 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NBPHLDOP_01401 3.57e-201 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NBPHLDOP_01402 1.44e-311 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NBPHLDOP_01403 3.25e-291 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NBPHLDOP_01404 7.24e-102 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NBPHLDOP_01405 5.58e-60 ylmG - - S ko:K02221 - ko00000,ko02044 integral membrane protein
NBPHLDOP_01406 2.14e-188 ylmH - - S - - - S4 domain protein
NBPHLDOP_01407 2.12e-122 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA protein
NBPHLDOP_01408 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NBPHLDOP_01409 4.62e-48 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
NBPHLDOP_01410 5.93e-207 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
NBPHLDOP_01411 0.0 ydiC1 - - EGP - - - Major Facilitator
NBPHLDOP_01412 7.29e-270 yaaN - - P - - - Toxic anion resistance protein (TelA)
NBPHLDOP_01413 2.8e-151 - - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
NBPHLDOP_01414 1.83e-124 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
NBPHLDOP_01415 1.42e-39 - - - - - - - -
NBPHLDOP_01416 1.95e-159 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NBPHLDOP_01417 1.39e-278 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
NBPHLDOP_01418 1.21e-75 XK27_04120 - - S - - - Putative amino acid metabolism
NBPHLDOP_01419 0.0 uvrA2 - - L - - - ABC transporter
NBPHLDOP_01420 0.0 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NBPHLDOP_01422 8.1e-160 pgm6 - - G - - - phosphoglycerate mutase
NBPHLDOP_01423 1.62e-151 - - - S - - - repeat protein
NBPHLDOP_01424 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NBPHLDOP_01425 2.86e-312 - - - S - - - Sterol carrier protein domain
NBPHLDOP_01426 2.55e-46 ytlR - - I - - - Diacylglycerol kinase catalytic domain
NBPHLDOP_01427 3.58e-145 ytlR - - I - - - Diacylglycerol kinase catalytic domain
NBPHLDOP_01428 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NBPHLDOP_01429 2.02e-43 ykzG - - S - - - Belongs to the UPF0356 family
NBPHLDOP_01430 1.11e-95 - - - - - - - -
NBPHLDOP_01431 4.23e-64 - - - - - - - -
NBPHLDOP_01432 4.82e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NBPHLDOP_01433 5.13e-112 - - - S - - - E1-E2 ATPase
NBPHLDOP_01434 1.42e-267 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
NBPHLDOP_01435 1.15e-232 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
NBPHLDOP_01436 0.0 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NBPHLDOP_01437 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
NBPHLDOP_01438 4.32e-202 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 L-malate dehydrogenase activity
NBPHLDOP_01439 6.15e-62 yktA - - S - - - Belongs to the UPF0223 family
NBPHLDOP_01440 3.56e-189 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
NBPHLDOP_01441 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
NBPHLDOP_01442 1.66e-269 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NBPHLDOP_01443 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NBPHLDOP_01444 8.46e-84 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
NBPHLDOP_01445 9.93e-130 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
NBPHLDOP_01446 1.08e-113 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NBPHLDOP_01447 9.02e-234 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
NBPHLDOP_01448 1.09e-151 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
NBPHLDOP_01449 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
NBPHLDOP_01450 5.08e-222 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
NBPHLDOP_01451 1.44e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
NBPHLDOP_01453 5e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NBPHLDOP_01454 3.82e-62 - - - - - - - -
NBPHLDOP_01455 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NBPHLDOP_01456 1.93e-213 - - - S - - - Tetratricopeptide repeat
NBPHLDOP_01457 4.73e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NBPHLDOP_01458 0.0 yknV - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
NBPHLDOP_01459 9.55e-288 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NBPHLDOP_01460 1.19e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NBPHLDOP_01461 2.74e-138 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
NBPHLDOP_01462 2.28e-63 - - - S - - - mazG nucleotide pyrophosphohydrolase
NBPHLDOP_01463 3.33e-28 - - - - - - - -
NBPHLDOP_01464 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
NBPHLDOP_01465 6.58e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NBPHLDOP_01466 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NBPHLDOP_01467 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
NBPHLDOP_01468 2.76e-218 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NBPHLDOP_01469 1.61e-169 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
NBPHLDOP_01470 5.83e-310 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NBPHLDOP_01471 0.0 oatA - - I - - - Acyltransferase
NBPHLDOP_01472 2.71e-233 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NBPHLDOP_01473 1.83e-183 yqjQ - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
NBPHLDOP_01474 2.47e-65 - - - S - - - Lipopolysaccharide assembly protein A domain
NBPHLDOP_01475 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NBPHLDOP_01476 1.35e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
NBPHLDOP_01477 6.3e-123 - - - K - - - Domain of unknown function (DUF1836)
NBPHLDOP_01478 0.0 ycjM 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 5'-nucleotidase, C-terminal domain
NBPHLDOP_01479 1.49e-185 - - - - - - - -
NBPHLDOP_01480 3.31e-35 - - - S - - - Protein of unknown function (DUF2929)
NBPHLDOP_01481 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
NBPHLDOP_01482 2.21e-227 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NBPHLDOP_01483 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
NBPHLDOP_01484 2.6e-96 ytwI - - S - - - Protein of unknown function (DUF441)
NBPHLDOP_01485 1.03e-207 yitL - - S ko:K00243 - ko00000 S1 domain
NBPHLDOP_01486 9.95e-211 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
NBPHLDOP_01488 1.59e-88 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NBPHLDOP_01489 5.33e-160 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NBPHLDOP_01490 8.74e-139 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NBPHLDOP_01491 1.1e-175 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NBPHLDOP_01492 1.52e-123 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NBPHLDOP_01493 1.16e-60 fer - - C ko:K05337 - ko00000 4Fe-4S single cluster domain of Ferredoxin I
NBPHLDOP_01494 2.72e-236 - - - S - - - Helix-turn-helix domain
NBPHLDOP_01495 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
NBPHLDOP_01496 6.76e-111 - - - M - - - Lysin motif
NBPHLDOP_01497 2.04e-149 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
NBPHLDOP_01498 1.72e-303 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
NBPHLDOP_01499 7.41e-312 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
NBPHLDOP_01500 1.2e-54 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NBPHLDOP_01501 1.52e-302 XK27_05225 - - S - - - Tetratricopeptide repeat protein
NBPHLDOP_01502 8.71e-200 ypjC - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NBPHLDOP_01503 5.31e-284 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NBPHLDOP_01504 2.95e-110 - - - - - - - -
NBPHLDOP_01505 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
NBPHLDOP_01506 2.96e-244 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NBPHLDOP_01507 3.64e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NBPHLDOP_01508 1.83e-148 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
NBPHLDOP_01509 4.9e-190 WQ51_01275 - - S - - - EDD domain protein, DegV family
NBPHLDOP_01510 2.93e-197 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
NBPHLDOP_01511 3.18e-147 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
NBPHLDOP_01512 4.47e-113 msrA 1.8.4.11 - C ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NBPHLDOP_01513 1.03e-54 yozE - - S - - - Belongs to the UPF0346 family
NBPHLDOP_01514 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
NBPHLDOP_01515 1.3e-52 XK27_02555 - - - - - - -
NBPHLDOP_01517 7.6e-246 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
NBPHLDOP_01518 2.52e-195 - - - K - - - Helix-turn-helix domain
NBPHLDOP_01520 2.53e-205 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NBPHLDOP_01521 1.4e-179 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NBPHLDOP_01522 3.27e-189 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
NBPHLDOP_01523 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NBPHLDOP_01524 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NBPHLDOP_01525 1.66e-216 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
NBPHLDOP_01526 2.06e-119 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NBPHLDOP_01527 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NBPHLDOP_01528 1.32e-219 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
NBPHLDOP_01529 6.92e-141 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NBPHLDOP_01530 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NBPHLDOP_01531 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NBPHLDOP_01532 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
NBPHLDOP_01533 1.27e-217 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NBPHLDOP_01534 2.6e-232 - - - K - - - LysR substrate binding domain
NBPHLDOP_01535 5.59e-221 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
NBPHLDOP_01536 3.63e-270 xerS - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
NBPHLDOP_01537 7.18e-79 - - - - - - - -
NBPHLDOP_01538 0.0 XK27_05700 - - V ko:K02004,ko:K19084 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 FtsX-like permease family
NBPHLDOP_01539 2.68e-176 XK27_05695 - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NBPHLDOP_01540 1.09e-222 kinG - - T - - - Histidine kinase-like ATPases
NBPHLDOP_01541 1.75e-159 - - - T - - - Transcriptional regulatory protein, C terminal
NBPHLDOP_01542 5.52e-243 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
NBPHLDOP_01543 1.07e-43 - - - K - - - Acetyltransferase (GNAT) domain
NBPHLDOP_01544 6.04e-94 - - - K - - - Acetyltransferase (GNAT) domain
NBPHLDOP_01545 2.92e-144 - - - C - - - Nitroreductase family
NBPHLDOP_01546 2.07e-261 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NBPHLDOP_01547 8.66e-70 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
NBPHLDOP_01548 1.01e-77 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NBPHLDOP_01549 7.36e-172 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NBPHLDOP_01550 1.37e-160 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NBPHLDOP_01551 4.89e-146 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NBPHLDOP_01552 3.22e-135 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
NBPHLDOP_01553 4.33e-297 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NBPHLDOP_01554 2.06e-144 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NBPHLDOP_01555 3.83e-278 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NBPHLDOP_01556 6.2e-264 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NBPHLDOP_01557 9.68e-134 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
NBPHLDOP_01558 6.21e-207 - - - S - - - EDD domain protein, DegV family
NBPHLDOP_01559 0.0 FbpA - - K - - - Fibronectin-binding protein
NBPHLDOP_01560 6.51e-69 - - - S - - - MazG-like family
NBPHLDOP_01561 1.42e-250 pfoS/R - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
NBPHLDOP_01562 2.13e-227 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NBPHLDOP_01563 9.61e-289 bfmBB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
NBPHLDOP_01564 2.14e-234 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, pyrimidine binding domain
NBPHLDOP_01565 9.14e-239 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
NBPHLDOP_01566 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
NBPHLDOP_01567 6.69e-263 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Acetokinase family
NBPHLDOP_01568 1.74e-190 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Phosphate acetyl/butaryl transferase
NBPHLDOP_01569 1.02e-145 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NBPHLDOP_01570 4.62e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NBPHLDOP_01571 5.67e-200 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NBPHLDOP_01572 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
NBPHLDOP_01573 5.32e-267 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NBPHLDOP_01574 5.35e-307 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NBPHLDOP_01575 9.29e-230 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
NBPHLDOP_01576 1.64e-299 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
NBPHLDOP_01577 1.05e-125 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NBPHLDOP_01578 6.3e-223 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NBPHLDOP_01579 2.41e-106 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NBPHLDOP_01580 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
NBPHLDOP_01581 8.5e-61 - - - S - - - Family of unknown function (DUF5322)
NBPHLDOP_01582 2.37e-91 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
NBPHLDOP_01583 5.13e-144 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
NBPHLDOP_01584 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NBPHLDOP_01585 3.85e-63 - - - - - - - -
NBPHLDOP_01586 0.0 - - - S - - - Mga helix-turn-helix domain
NBPHLDOP_01587 8.72e-52 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
NBPHLDOP_01588 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NBPHLDOP_01589 8.83e-242 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NBPHLDOP_01590 2.26e-212 lysR - - K - - - Transcriptional regulator
NBPHLDOP_01591 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
NBPHLDOP_01592 3.5e-249 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
NBPHLDOP_01593 8.85e-47 - - - - - - - -
NBPHLDOP_01594 2.2e-223 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
NBPHLDOP_01595 2.31e-278 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
NBPHLDOP_01596 7.09e-88 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NBPHLDOP_01597 6.54e-138 ypsA - - S - - - Belongs to the UPF0398 family
NBPHLDOP_01598 5.12e-157 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NBPHLDOP_01599 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
NBPHLDOP_01600 5.94e-111 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
NBPHLDOP_01601 7.61e-148 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NBPHLDOP_01602 3.19e-146 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
NBPHLDOP_01603 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
NBPHLDOP_01604 9.84e-281 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NBPHLDOP_01605 3.5e-112 ypmB - - S - - - Protein conserved in bacteria
NBPHLDOP_01607 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
NBPHLDOP_01608 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
NBPHLDOP_01609 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NBPHLDOP_01610 2.64e-215 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
NBPHLDOP_01611 1.62e-232 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
NBPHLDOP_01612 5.56e-245 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NBPHLDOP_01613 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
NBPHLDOP_01614 4.61e-224 - - - - - - - -
NBPHLDOP_01615 5.49e-185 - - - - - - - -
NBPHLDOP_01616 2.32e-79 yitW - - S - - - Iron-sulfur cluster assembly protein
NBPHLDOP_01617 1.48e-37 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
NBPHLDOP_01618 1.4e-191 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NBPHLDOP_01619 1.61e-162 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
NBPHLDOP_01620 9.19e-249 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NBPHLDOP_01621 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NBPHLDOP_01622 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
NBPHLDOP_01623 1.48e-219 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
NBPHLDOP_01624 4.99e-72 - - - - - - - -
NBPHLDOP_01625 7.92e-74 - - - - - - - -
NBPHLDOP_01626 2.11e-183 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
NBPHLDOP_01627 1.17e-217 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NBPHLDOP_01628 1.38e-84 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NBPHLDOP_01629 6.78e-82 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
NBPHLDOP_01630 5.09e-107 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NBPHLDOP_01631 8.02e-230 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
NBPHLDOP_01633 1.81e-88 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
NBPHLDOP_01634 3.98e-29 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
NBPHLDOP_01635 8.44e-199 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NBPHLDOP_01636 1.05e-211 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NBPHLDOP_01637 3.1e-216 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NBPHLDOP_01638 7.56e-108 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
NBPHLDOP_01639 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NBPHLDOP_01640 3.25e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
NBPHLDOP_01642 7.04e-217 - - - C - - - nadph quinone reductase
NBPHLDOP_01643 2.55e-100 - - - - - - - -
NBPHLDOP_01644 5.67e-191 - - - K - - - Helix-turn-helix
NBPHLDOP_01645 0.0 - - - - - - - -
NBPHLDOP_01646 2.41e-201 - - - V - - - ABC transporter
NBPHLDOP_01647 2.36e-109 - - - FG - - - adenosine 5'-monophosphoramidase activity
NBPHLDOP_01648 1.98e-314 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
NBPHLDOP_01649 1.35e-150 - - - J - - - HAD-hyrolase-like
NBPHLDOP_01650 5.55e-100 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NBPHLDOP_01651 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NBPHLDOP_01652 5.49e-58 - - - - - - - -
NBPHLDOP_01653 3.13e-170 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NBPHLDOP_01654 1.74e-222 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
NBPHLDOP_01655 3.49e-113 XK27_03960 - - S - - - Protein of unknown function (DUF3013)
NBPHLDOP_01656 1.54e-144 - 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
NBPHLDOP_01657 2.23e-50 - - - - - - - -
NBPHLDOP_01658 8.05e-88 - - - S - - - Protein of unknown function (DUF1093)
NBPHLDOP_01659 6.1e-27 - - - - - - - -
NBPHLDOP_01660 1.72e-64 - - - - - - - -
NBPHLDOP_01661 9.31e-117 - - - K - - - Acetyltransferase (GNAT) domain
NBPHLDOP_01663 3.1e-143 - - - S - - - Flavodoxin-like fold
NBPHLDOP_01664 1.54e-130 - - - K - - - Bacterial regulatory proteins, tetR family
NBPHLDOP_01665 7.25e-200 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 N-formylglutamate amidohydrolase
NBPHLDOP_01666 1.66e-71 XK27_08430 - - S - - - Staphylococcal protein of unknown function (DUF960)
NBPHLDOP_01667 2.01e-118 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NBPHLDOP_01668 1.7e-123 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NBPHLDOP_01669 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
NBPHLDOP_01670 8.85e-76 - - - - - - - -
NBPHLDOP_01671 2.05e-109 - - - S - - - ASCH
NBPHLDOP_01672 1.32e-33 - - - - - - - -
NBPHLDOP_01673 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NBPHLDOP_01674 9.45e-261 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NBPHLDOP_01675 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
NBPHLDOP_01676 3.18e-127 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NBPHLDOP_01677 5.57e-247 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NBPHLDOP_01678 1.01e-229 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
NBPHLDOP_01679 1.22e-39 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
NBPHLDOP_01680 2.3e-227 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
NBPHLDOP_01681 1.64e-212 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NBPHLDOP_01682 4.46e-183 terC - - P - - - Integral membrane protein TerC family
NBPHLDOP_01683 1.27e-76 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NBPHLDOP_01684 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NBPHLDOP_01685 1.29e-60 ylxQ - - J - - - ribosomal protein
NBPHLDOP_01686 9.63e-61 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
NBPHLDOP_01687 4.13e-277 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
NBPHLDOP_01688 1.33e-110 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
NBPHLDOP_01689 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NBPHLDOP_01690 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NBPHLDOP_01691 3.52e-292 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
NBPHLDOP_01692 7.66e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
NBPHLDOP_01693 6.38e-181 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NBPHLDOP_01694 1.73e-121 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NBPHLDOP_01695 5.86e-167 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
NBPHLDOP_01696 1.63e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NBPHLDOP_01697 1.18e-182 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
NBPHLDOP_01698 1.88e-61 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
NBPHLDOP_01699 2.05e-168 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
NBPHLDOP_01700 8.45e-160 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
NBPHLDOP_01701 1.17e-293 yhdG - - E ko:K03294 - ko00000 Amino Acid
NBPHLDOP_01702 4.28e-181 yejC - - S - - - Protein of unknown function (DUF1003)
NBPHLDOP_01703 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NBPHLDOP_01704 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NBPHLDOP_01705 1.39e-40 yneF - - S ko:K09976 - ko00000 UPF0154 protein
NBPHLDOP_01706 2.96e-48 ynzC - - S - - - UPF0291 protein
NBPHLDOP_01707 9.42e-28 - - - - - - - -
NBPHLDOP_01708 2e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NBPHLDOP_01709 6.15e-186 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
NBPHLDOP_01710 2.16e-120 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NBPHLDOP_01711 1.55e-51 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
NBPHLDOP_01712 2.97e-59 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
NBPHLDOP_01713 2.16e-303 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NBPHLDOP_01714 1.26e-75 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NBPHLDOP_01715 7.91e-70 - - - - - - - -
NBPHLDOP_01716 1.57e-233 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NBPHLDOP_01717 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
NBPHLDOP_01718 6.59e-160 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NBPHLDOP_01719 0.0 oppA1 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NBPHLDOP_01720 1.8e-197 oppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NBPHLDOP_01721 3.2e-216 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NBPHLDOP_01722 5.65e-229 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NBPHLDOP_01723 4.24e-247 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NBPHLDOP_01724 3.21e-49 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NBPHLDOP_01725 1.41e-241 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NBPHLDOP_01726 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NBPHLDOP_01727 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
NBPHLDOP_01728 5.83e-75 yloU - - S - - - Asp23 family, cell envelope-related function
NBPHLDOP_01729 2.29e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
NBPHLDOP_01730 2.62e-166 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
NBPHLDOP_01731 4.16e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
NBPHLDOP_01732 1.38e-221 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NBPHLDOP_01733 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
NBPHLDOP_01734 7.73e-176 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
NBPHLDOP_01735 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NBPHLDOP_01736 9.71e-226 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NBPHLDOP_01737 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NBPHLDOP_01738 3.4e-276 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NBPHLDOP_01739 1.77e-47 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NBPHLDOP_01740 2.52e-148 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
NBPHLDOP_01741 6.35e-46 - - - S ko:K07001 - ko00000 Patatin-like phospholipase
NBPHLDOP_01742 3.99e-56 - - - S ko:K07001 - ko00000 Patatin-like phospholipase
NBPHLDOP_01743 2.32e-67 - - - - - - - -
NBPHLDOP_01745 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
NBPHLDOP_01746 7.24e-97 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NBPHLDOP_01747 8.09e-197 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
NBPHLDOP_01748 1.56e-190 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NBPHLDOP_01749 1.42e-43 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NBPHLDOP_01750 1.56e-295 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NBPHLDOP_01751 4.46e-193 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NBPHLDOP_01752 2.34e-88 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NBPHLDOP_01753 9.44e-99 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
NBPHLDOP_01754 6.06e-132 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NBPHLDOP_01756 2.14e-259 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
NBPHLDOP_01757 1.6e-63 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
NBPHLDOP_01758 1.77e-74 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
NBPHLDOP_01759 5.83e-67 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
NBPHLDOP_01760 4.92e-18 - - - - - - - -
NBPHLDOP_01763 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NBPHLDOP_01764 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
NBPHLDOP_01765 1.32e-80 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
NBPHLDOP_01766 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
NBPHLDOP_01767 1.41e-305 ynbB - - P - - - aluminum resistance
NBPHLDOP_01768 3.25e-224 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NBPHLDOP_01769 3.33e-35 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
NBPHLDOP_01770 1.93e-96 yqhL - - P - - - Rhodanese-like protein
NBPHLDOP_01771 1.13e-228 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
NBPHLDOP_01772 6.79e-55 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
NBPHLDOP_01773 2.3e-158 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
NBPHLDOP_01774 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NBPHLDOP_01775 2.14e-80 - - - M - - - Bacterial membrane protein, YfhO
NBPHLDOP_01776 1.72e-242 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
NBPHLDOP_01777 0.0 - - - S - - - Bacterial membrane protein YfhO
NBPHLDOP_01778 8.3e-70 yneR - - S - - - Belongs to the HesB IscA family
NBPHLDOP_01779 2.04e-149 vraR - - K ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
NBPHLDOP_01780 1.39e-233 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NBPHLDOP_01781 1.9e-165 yvqF - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
NBPHLDOP_01782 1.05e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NBPHLDOP_01783 3.43e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
NBPHLDOP_01784 1.82e-265 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NBPHLDOP_01785 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NBPHLDOP_01786 1.24e-259 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NBPHLDOP_01787 1.2e-87 yodB - - K - - - Transcriptional regulator, HxlR family
NBPHLDOP_01788 3.09e-122 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NBPHLDOP_01789 4.47e-178 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NBPHLDOP_01790 4.17e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
NBPHLDOP_01791 8.99e-229 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NBPHLDOP_01792 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NBPHLDOP_01793 1.01e-157 csrR - - K - - - response regulator
NBPHLDOP_01794 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NBPHLDOP_01795 1.9e-53 - - - S - - - Psort location Cytoplasmic, score
NBPHLDOP_01796 3.82e-128 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
NBPHLDOP_01797 1.67e-270 ylbM - - S - - - Belongs to the UPF0348 family
NBPHLDOP_01798 8.74e-181 yccK - - Q - - - ubiE/COQ5 methyltransferase family
NBPHLDOP_01799 1.18e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NBPHLDOP_01800 1.31e-141 yqeK - - H - - - Hydrolase, HD family
NBPHLDOP_01801 5.06e-168 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NBPHLDOP_01802 3.95e-65 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
NBPHLDOP_01803 3.02e-262 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
NBPHLDOP_01804 6.63e-127 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
NBPHLDOP_01805 4.11e-222 ykcA - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NBPHLDOP_01806 1.93e-243 mhqA_2 - - E ko:K15975 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NBPHLDOP_01807 2.14e-157 mhqD - - S ko:K06999 - ko00000 Dienelactone hydrolase family
NBPHLDOP_01808 4.5e-233 - - - C - - - Alcohol dehydrogenase GroES-like domain
NBPHLDOP_01809 1.01e-130 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
NBPHLDOP_01810 1.02e-74 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NBPHLDOP_01811 1.13e-36 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
NBPHLDOP_01812 7.46e-101 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NBPHLDOP_01813 2.31e-167 - - - S - - - SseB protein N-terminal domain
NBPHLDOP_01814 5.3e-70 - - - - - - - -
NBPHLDOP_01815 4.61e-137 yrgI 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Histidine phosphatase superfamily (branch 1)
NBPHLDOP_01816 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NBPHLDOP_01818 2.02e-219 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
NBPHLDOP_01819 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
NBPHLDOP_01820 2.06e-103 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NBPHLDOP_01821 2.82e-132 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NBPHLDOP_01822 7.86e-207 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NBPHLDOP_01823 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NBPHLDOP_01824 4.41e-156 ybhL - - S ko:K06890 - ko00000 Inhibitor of apoptosis-promoting Bax1
NBPHLDOP_01825 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
NBPHLDOP_01826 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NBPHLDOP_01827 5.48e-150 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NBPHLDOP_01828 5.32e-73 ytpP - - CO - - - Thioredoxin
NBPHLDOP_01830 8.13e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NBPHLDOP_01831 4.51e-189 ytmP - - M - - - Choline/ethanolamine kinase
NBPHLDOP_01832 6.39e-279 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NBPHLDOP_01833 2.4e-172 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NBPHLDOP_01834 1.67e-99 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
NBPHLDOP_01835 2.44e-82 - - - S - - - YtxH-like protein
NBPHLDOP_01836 5.26e-205 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NBPHLDOP_01837 8.42e-232 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
NBPHLDOP_01838 1.03e-72 - - - S - - - Control of competence regulator ComK, YlbF/YmcA
NBPHLDOP_01839 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NBPHLDOP_01840 1.3e-198 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NBPHLDOP_01841 3.31e-98 argR1 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NBPHLDOP_01842 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
NBPHLDOP_01844 1.97e-88 - - - - - - - -
NBPHLDOP_01845 4.04e-32 - - - - - - - -
NBPHLDOP_01846 3.67e-227 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate
NBPHLDOP_01847 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
NBPHLDOP_01848 3.53e-158 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NBPHLDOP_01849 1.13e-89 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NBPHLDOP_01850 3.42e-178 yhfI - - S - - - Metallo-beta-lactamase superfamily
NBPHLDOP_01851 7.88e-121 traP 1.14.99.57, 6.2.1.3 - S ko:K01897,ko:K21481 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 heme oxygenase (decyclizing) activity
NBPHLDOP_01852 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
NBPHLDOP_01853 1.14e-177 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NBPHLDOP_01854 1.57e-159 rrp1 - - K ko:K02483 - ko00000,ko02022 response regulator
NBPHLDOP_01855 1.21e-266 - - - T ko:K19168 - ko00000,ko02048 His Kinase A (phosphoacceptor) domain
NBPHLDOP_01856 1.54e-141 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NBPHLDOP_01857 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5 - P ko:K01533,ko:K01534 - ko00000,ko01000 P-type ATPase
NBPHLDOP_01858 2.87e-101 copR - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
NBPHLDOP_01859 4.69e-301 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
NBPHLDOP_01860 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
NBPHLDOP_01861 2.36e-130 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NBPHLDOP_01862 7.52e-239 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
NBPHLDOP_01863 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NBPHLDOP_01864 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NBPHLDOP_01865 3.05e-168 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NBPHLDOP_01866 7.25e-56 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NBPHLDOP_01867 1.63e-172 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
NBPHLDOP_01868 8.98e-276 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NBPHLDOP_01869 2.66e-102 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NBPHLDOP_01870 6.68e-136 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
NBPHLDOP_01871 0.0 iolT - - EGP ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NBPHLDOP_01872 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NBPHLDOP_01873 1.02e-51 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
NBPHLDOP_01874 9.5e-39 - - - - - - - -
NBPHLDOP_01875 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
NBPHLDOP_01876 1.17e-61 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
NBPHLDOP_01878 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NBPHLDOP_01879 1.44e-311 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
NBPHLDOP_01880 4.17e-262 yueF - - S - - - AI-2E family transporter
NBPHLDOP_01881 1.13e-97 yjcF - - S - - - Acetyltransferase (GNAT) domain
NBPHLDOP_01882 1.92e-123 - - - - - - - -
NBPHLDOP_01883 1.1e-134 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
NBPHLDOP_01884 3.39e-183 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
NBPHLDOP_01885 0.0 frvR - - K ko:K02538,ko:K03483,ko:K09685,ko:K18531 - ko00000,ko03000 transcriptional antiterminator
NBPHLDOP_01886 6.46e-83 - - - - - - - -
NBPHLDOP_01887 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NBPHLDOP_01888 4.13e-104 - - - F - - - Nucleoside 2-deoxyribosyltransferase
NBPHLDOP_01889 2.13e-172 - - - K ko:K03489 - ko00000,ko03000 UTRA
NBPHLDOP_01890 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NBPHLDOP_01891 0.0 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NBPHLDOP_01892 2.36e-111 - - - - - - - -
NBPHLDOP_01893 1.94e-66 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
NBPHLDOP_01894 6.27e-67 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NBPHLDOP_01895 0.0 poxL 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NBPHLDOP_01896 2.6e-279 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
NBPHLDOP_01897 1.63e-267 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
NBPHLDOP_01898 1.41e-265 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
NBPHLDOP_01899 7.23e-66 - - - - - - - -
NBPHLDOP_01900 3.47e-207 - - - G - - - Xylose isomerase domain protein TIM barrel
NBPHLDOP_01901 4.44e-134 - - - V ko:K07448 - ko00000,ko02048 Restriction endonuclease
NBPHLDOP_01902 2.25e-201 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 converts alpha-aldose to the beta-anomer
NBPHLDOP_01903 1.88e-272 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
NBPHLDOP_01904 4.33e-132 - - - S - - - ECF transporter, substrate-specific component
NBPHLDOP_01906 1.4e-105 - - - K - - - Acetyltransferase GNAT Family
NBPHLDOP_01907 1.65e-111 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
NBPHLDOP_01908 2.36e-167 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NBPHLDOP_01909 2.83e-188 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NBPHLDOP_01910 2.53e-48 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
NBPHLDOP_01911 7.4e-165 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
NBPHLDOP_01913 2.88e-96 - - - - - - - -
NBPHLDOP_01914 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
NBPHLDOP_01915 4.84e-278 - - - V - - - Beta-lactamase
NBPHLDOP_01916 2.51e-195 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NBPHLDOP_01917 3.31e-282 - - - V - - - Beta-lactamase
NBPHLDOP_01918 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NBPHLDOP_01919 1.62e-161 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
NBPHLDOP_01920 2.14e-279 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
NBPHLDOP_01921 1.13e-177 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NBPHLDOP_01922 0.0 yuxL 3.4.19.1 - E ko:K01303 - ko00000,ko01000,ko01002 Prolyl oligopeptidase family
NBPHLDOP_01925 2.17e-205 - - - S - - - Calcineurin-like phosphoesterase
NBPHLDOP_01926 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
NBPHLDOP_01927 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NBPHLDOP_01928 1.71e-87 - - - - - - - -
NBPHLDOP_01929 6.13e-100 - - - S - - - function, without similarity to other proteins
NBPHLDOP_01930 0.0 - - - G - - - MFS/sugar transport protein
NBPHLDOP_01931 4.07e-296 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 Alpha-L-fucosidase
NBPHLDOP_01932 8.15e-77 - - - - - - - -
NBPHLDOP_01933 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
NBPHLDOP_01934 6.28e-25 - - - S - - - Virus attachment protein p12 family
NBPHLDOP_01935 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
NBPHLDOP_01936 8.65e-56 feoA - - P ko:K04758 - ko00000,ko02000 FeoA
NBPHLDOP_01937 2.02e-168 - - - E - - - lipolytic protein G-D-S-L family
NBPHLDOP_01940 3.72e-152 - - - S ko:K07118 - ko00000 NAD(P)H-binding
NBPHLDOP_01941 8.14e-79 - - - S - - - MucBP domain
NBPHLDOP_01942 9.73e-109 - - - - - - - -
NBPHLDOP_01946 5.19e-90 - - - S - - - COG NOG38524 non supervised orthologous group
NBPHLDOP_01949 1.33e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NBPHLDOP_01950 0.0 - - - K - - - Mga helix-turn-helix domain
NBPHLDOP_01951 0.0 - - - K - - - Mga helix-turn-helix domain
NBPHLDOP_01952 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
NBPHLDOP_01954 4.15e-170 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
NBPHLDOP_01955 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
NBPHLDOP_01956 8.32e-128 - - - - - - - -
NBPHLDOP_01957 2.94e-128 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NBPHLDOP_01958 3e-249 - - - S - - - Protein of unknown function C-terminal (DUF3324)
NBPHLDOP_01959 8.02e-114 - - - - - - - -
NBPHLDOP_01960 1.43e-25 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NBPHLDOP_01961 3.08e-152 sodA 1.15.1.1 - C ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NBPHLDOP_01962 2.44e-208 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NBPHLDOP_01963 1.25e-201 - - - I - - - alpha/beta hydrolase fold
NBPHLDOP_01964 1.61e-41 - - - - - - - -
NBPHLDOP_01965 7.43e-97 - - - - - - - -
NBPHLDOP_01966 1.99e-199 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NBPHLDOP_01967 4.14e-163 citR - - K - - - FCD
NBPHLDOP_01968 0.0 oadA 4.1.1.3 - C ko:K01571 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000,ko02000 Conserved carboxylase domain
NBPHLDOP_01969 1.18e-122 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
NBPHLDOP_01970 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
NBPHLDOP_01971 7.46e-201 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
NBPHLDOP_01972 3.41e-65 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
NBPHLDOP_01973 4.66e-232 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NBPHLDOP_01974 3.26e-07 - - - - - - - -
NBPHLDOP_01975 5.58e-251 oadB 4.1.1.3 - C ko:K01572 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000,ko02000 Na+-transporting oxaloacetate decarboxylase beta subunit
NBPHLDOP_01976 1.71e-62 oadG - - I - - - Biotin-requiring enzyme
NBPHLDOP_01977 3.17e-71 - - - - - - - -
NBPHLDOP_01978 1.43e-307 citM - - C ko:K03300 - ko00000 Citrate transporter
NBPHLDOP_01979 1.72e-53 - - - - - - - -
NBPHLDOP_01980 2.68e-135 kptA - - J ko:K07559 - ko00000,ko01000,ko03016 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
NBPHLDOP_01981 2.46e-113 - - - K - - - GNAT family
NBPHLDOP_01982 6.93e-140 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
NBPHLDOP_01983 1.13e-75 padR - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
NBPHLDOP_01984 7.71e-192 ORF00048 - - - - - - -
NBPHLDOP_01985 6.35e-177 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
NBPHLDOP_01986 1.42e-216 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NBPHLDOP_01987 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
NBPHLDOP_01988 1.7e-148 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
NBPHLDOP_01989 0.0 - - - EGP - - - Major Facilitator
NBPHLDOP_01990 2.86e-161 - - - S ko:K07090 - ko00000 membrane transporter protein
NBPHLDOP_01991 6.95e-239 - - - K - - - Helix-turn-helix XRE-family like proteins
NBPHLDOP_01992 4.73e-209 - - - S - - - Alpha beta hydrolase
NBPHLDOP_01993 8.13e-82 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
NBPHLDOP_01994 1.23e-163 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NBPHLDOP_01995 4.41e-20 - - - - - - - -
NBPHLDOP_01996 6.6e-134 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NBPHLDOP_01997 1.71e-206 - - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
NBPHLDOP_01998 3.16e-262 - - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
NBPHLDOP_02000 7.11e-228 - - - EP ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NBPHLDOP_02001 2.54e-216 - - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NBPHLDOP_02002 0.0 - - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
NBPHLDOP_02003 1.19e-164 - - - S - - - DJ-1/PfpI family
NBPHLDOP_02004 2.12e-70 - - - K - - - Transcriptional
NBPHLDOP_02005 6.68e-52 - - - - - - - -
NBPHLDOP_02006 0.0 - - - V - - - ABC transporter transmembrane region
NBPHLDOP_02007 0.0 - - - V ko:K06147,ko:K06148,ko:K11085,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter transmembrane region
NBPHLDOP_02009 3.24e-89 - - - S - - - Iron-sulphur cluster biosynthesis
NBPHLDOP_02010 7.96e-20 - 2.7.1.39 - S ko:K02204 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Phosphotransferase enzyme family
NBPHLDOP_02011 0.0 - - - M - - - LysM domain
NBPHLDOP_02012 3.38e-173 zmp3 - - O - - - Zinc-dependent metalloprotease
NBPHLDOP_02013 4.82e-226 - - - L - - - Transposase and inactivated derivatives, IS30 family
NBPHLDOP_02014 1.23e-176 - - - K - - - DeoR C terminal sensor domain
NBPHLDOP_02016 7.74e-68 lciIC - - K - - - Helix-turn-helix domain
NBPHLDOP_02017 9.14e-129 yjdB - - S - - - Domain of unknown function (DUF4767)
NBPHLDOP_02018 1.35e-192 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NBPHLDOP_02019 2.09e-98 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NBPHLDOP_02020 8.4e-150 - - - - - - - -
NBPHLDOP_02022 1.51e-77 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
NBPHLDOP_02023 8.37e-108 - - - L - - - Transposase DDE domain
NBPHLDOP_02024 2.44e-143 - - - L ko:K07482 - ko00000 Transposase and inactivated derivatives, IS30 family
NBPHLDOP_02025 1.5e-107 - - - - - - - -
NBPHLDOP_02026 1.4e-58 - - - L ko:K07483 - ko00000 Homeodomain-like domain
NBPHLDOP_02027 4.17e-189 - - - L - - - COG2801 Transposase and inactivated derivatives
NBPHLDOP_02028 4.68e-71 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
NBPHLDOP_02029 2.96e-212 - - - P - - - CorA-like Mg2+ transporter protein
NBPHLDOP_02030 4.82e-226 - - - L - - - Transposase and inactivated derivatives, IS30 family
NBPHLDOP_02031 3.96e-224 - - - I - - - Alpha/beta hydrolase family
NBPHLDOP_02032 3.74e-204 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
NBPHLDOP_02033 6e-269 pepA - - E - - - M42 glutamyl aminopeptidase
NBPHLDOP_02034 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NBPHLDOP_02035 2.14e-163 tnp1216 - - L ko:K07498 - ko00000 DDE domain
NBPHLDOP_02036 1.4e-09 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
NBPHLDOP_02037 5.78e-32 - - - - - - - -
NBPHLDOP_02038 2.56e-86 - - - - - - - -
NBPHLDOP_02040 1.35e-33 - - - S - - - Domain of unknown function (DUF3173)
NBPHLDOP_02041 3e-294 - - - L - - - Belongs to the 'phage' integrase family
NBPHLDOP_02042 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
NBPHLDOP_02043 8.03e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
NBPHLDOP_02045 3.38e-56 - - - - - - - -
NBPHLDOP_02046 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NBPHLDOP_02047 1.5e-111 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
NBPHLDOP_02048 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NBPHLDOP_02049 2.51e-28 - - - - - - - -
NBPHLDOP_02050 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
NBPHLDOP_02051 1.97e-230 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
NBPHLDOP_02052 1.11e-106 yjhE - - S - - - Phage tail protein
NBPHLDOP_02053 1.09e-307 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NBPHLDOP_02054 4.91e-241 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
NBPHLDOP_02055 4.03e-164 gpm2 - - G - - - Phosphoglycerate mutase family
NBPHLDOP_02056 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NBPHLDOP_02057 2.68e-174 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NBPHLDOP_02058 0.0 - - - E - - - Amino Acid
NBPHLDOP_02059 8.52e-212 - - - I - - - Diacylglycerol kinase catalytic domain
NBPHLDOP_02060 4.57e-304 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NBPHLDOP_02061 4.67e-215 nodB3 - - G - - - Polysaccharide deacetylase
NBPHLDOP_02062 0.0 - - - S - - - Glucosyl transferase GtrII
NBPHLDOP_02063 4.68e-300 - - - - - - - -
NBPHLDOP_02064 3.07e-124 - - - - - - - -
NBPHLDOP_02065 1.19e-234 - - - M - - - Peptidase_C39 like family
NBPHLDOP_02066 1.12e-205 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NBPHLDOP_02067 8.36e-259 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NBPHLDOP_02068 1.55e-140 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NBPHLDOP_02069 7.88e-211 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NBPHLDOP_02071 9.51e-168 - - - - - - - -
NBPHLDOP_02072 0.0 cps2E - - M - - - Bacterial sugar transferase
NBPHLDOP_02073 8e-226 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
NBPHLDOP_02074 2.27e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NBPHLDOP_02075 1.44e-141 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NBPHLDOP_02076 1.23e-190 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NBPHLDOP_02077 6.35e-174 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NBPHLDOP_02078 8.02e-230 - - - - - - - -
NBPHLDOP_02080 3.91e-109 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
NBPHLDOP_02081 9.35e-15 - - - - - - - -
NBPHLDOP_02082 7.28e-144 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
NBPHLDOP_02083 7.28e-92 - - - K - - - Acetyltransferase (GNAT) domain
NBPHLDOP_02084 1.99e-197 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
NBPHLDOP_02085 1.55e-312 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NBPHLDOP_02086 1.32e-221 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NBPHLDOP_02087 5.83e-73 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NBPHLDOP_02088 3.12e-222 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NBPHLDOP_02089 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NBPHLDOP_02090 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NBPHLDOP_02091 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
NBPHLDOP_02092 1.45e-281 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
NBPHLDOP_02093 1.18e-255 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NBPHLDOP_02094 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NBPHLDOP_02095 1.06e-262 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
NBPHLDOP_02096 5.01e-136 - - - M - - - Sortase family
NBPHLDOP_02097 2.29e-187 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NBPHLDOP_02098 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 phosphatase activity
NBPHLDOP_02099 1.94e-86 spx2 - - P ko:K16509 - ko00000 ArsC family
NBPHLDOP_02100 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 associated with various cellular activities
NBPHLDOP_02101 4.87e-187 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
NBPHLDOP_02102 1.11e-205 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NBPHLDOP_02103 3.21e-243 - - - - - - - -
NBPHLDOP_02104 6.93e-169 - - - L - - - Transposase and inactivated derivatives
NBPHLDOP_02105 0.0 - - - L - - - Transposase DDE domain
NBPHLDOP_02106 1.65e-241 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NBPHLDOP_02107 4.21e-206 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NBPHLDOP_02108 7.16e-260 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NBPHLDOP_02109 1.55e-140 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NBPHLDOP_02110 3.21e-210 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NBPHLDOP_02111 4.13e-94 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
NBPHLDOP_02112 7.56e-208 - - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
NBPHLDOP_02113 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
NBPHLDOP_02114 2.93e-133 - - - S - - - Hexapeptide repeat of succinyl-transferase
NBPHLDOP_02115 7.01e-286 - - - S - - - O-antigen ligase like membrane protein
NBPHLDOP_02116 8.31e-234 - - - M - - - Glycosyltransferase like family 2
NBPHLDOP_02117 1.14e-276 - - - M - - - Glycosyl transferases group 1
NBPHLDOP_02118 3.79e-295 rgpAc - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 Domain of unknown function (DUF1972)
NBPHLDOP_02119 3.75e-165 ywqD - - D - - - Capsular exopolysaccharide family
NBPHLDOP_02120 1.43e-186 epsB - - M - - - biosynthesis protein
NBPHLDOP_02121 3.68e-170 - - - E - - - lipolytic protein G-D-S-L family
NBPHLDOP_02122 4.2e-106 ccl - - S - - - QueT transporter
NBPHLDOP_02123 4.62e-163 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
NBPHLDOP_02124 2.1e-49 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
NBPHLDOP_02125 6.56e-64 - - - K - - - sequence-specific DNA binding
NBPHLDOP_02126 1.07e-151 gpm5 - - G - - - Phosphoglycerate mutase family
NBPHLDOP_02127 3.15e-230 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NBPHLDOP_02128 4.99e-251 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NBPHLDOP_02129 3.01e-227 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NBPHLDOP_02130 1.4e-208 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NBPHLDOP_02131 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NBPHLDOP_02132 0.0 - - - EGP - - - Major Facilitator Superfamily
NBPHLDOP_02133 1.72e-242 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
NBPHLDOP_02134 4.1e-130 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NBPHLDOP_02135 1.98e-172 lutC - - S ko:K00782 - ko00000 LUD domain
NBPHLDOP_02136 0.0 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
NBPHLDOP_02137 1.7e-190 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
NBPHLDOP_02138 2.39e-109 - - - - - - - -
NBPHLDOP_02139 1.09e-68 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system cellobiose-specific component IIA
NBPHLDOP_02140 3.77e-270 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
NBPHLDOP_02141 1.62e-90 - - - S - - - Domain of unknown function (DUF3284)
NBPHLDOP_02142 7.79e-11 - - - - - - - -
NBPHLDOP_02143 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NBPHLDOP_02144 0.0 galA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
NBPHLDOP_02145 1.34e-176 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
NBPHLDOP_02146 3.16e-180 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2087)
NBPHLDOP_02147 0.0 - 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Helix-hairpin-helix containing domain
NBPHLDOP_02148 5.16e-17 - 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Helix-hairpin-helix containing domain
NBPHLDOP_02149 1.25e-102 - - - - - - - -
NBPHLDOP_02150 5.33e-76 - - - S - - - WxL domain surface cell wall-binding
NBPHLDOP_02151 4.13e-187 frlD1 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
NBPHLDOP_02152 0.0 hyuA - - EQ - - - Hydantoinase/oxoprolinase N-terminal region
NBPHLDOP_02153 9.15e-264 - - - S ko:K09703 - ko00000 Protein of unknown function (DUF917)
NBPHLDOP_02154 8.79e-283 - - - F ko:K10974 - ko00000,ko02000 Permease for cytosine/purines, uracil, thiamine, allantoin
NBPHLDOP_02155 1.44e-186 - - - - - - - -
NBPHLDOP_02156 0.0 - - - S - - - Protein of unknown function (DUF1524)
NBPHLDOP_02157 1.17e-261 hsdS 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
NBPHLDOP_02158 1.23e-223 - - - L - - - Belongs to the 'phage' integrase family
NBPHLDOP_02159 7.59e-122 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
NBPHLDOP_02160 4.23e-219 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
NBPHLDOP_02161 1.01e-165 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
NBPHLDOP_02162 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
NBPHLDOP_02163 2.47e-136 - - - - - - - -
NBPHLDOP_02164 0.0 - - - - - - - -
NBPHLDOP_02165 3.5e-271 - - - - - - - -
NBPHLDOP_02166 6.8e-95 pts26BCA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NBPHLDOP_02167 0.0 pts26BCA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NBPHLDOP_02168 0.0 malL 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NBPHLDOP_02169 3.69e-233 purR2 - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
NBPHLDOP_02170 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
NBPHLDOP_02171 5.14e-212 - - - GM - - - NmrA-like family
NBPHLDOP_02172 4.81e-298 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
NBPHLDOP_02173 1.19e-184 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
NBPHLDOP_02174 3.05e-194 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NBPHLDOP_02175 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
NBPHLDOP_02176 2.76e-99 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NBPHLDOP_02177 8.8e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NBPHLDOP_02178 6.98e-284 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NBPHLDOP_02179 2.03e-164 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
NBPHLDOP_02180 1.52e-212 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
NBPHLDOP_02181 5.55e-221 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
NBPHLDOP_02182 1.38e-45 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NBPHLDOP_02183 1.96e-226 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NBPHLDOP_02184 2.44e-99 - - - K - - - Winged helix DNA-binding domain
NBPHLDOP_02185 6.79e-95 - 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
NBPHLDOP_02186 7.3e-246 - - - E - - - Alpha/beta hydrolase family
NBPHLDOP_02187 5.57e-290 - - - C - - - Iron-containing alcohol dehydrogenase
NBPHLDOP_02188 1.72e-242 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
NBPHLDOP_02189 4.19e-65 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2316)
NBPHLDOP_02190 1.35e-88 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 MarR family
NBPHLDOP_02191 1.24e-14 tcaA - - S ko:K21463 - ko00000 response to antibiotic
NBPHLDOP_02192 3.72e-218 - - - S - - - Putative esterase
NBPHLDOP_02193 1.83e-256 - - - - - - - -
NBPHLDOP_02194 1.47e-136 - - - K - - - Transcriptional regulator, MarR family
NBPHLDOP_02195 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
NBPHLDOP_02196 4.68e-109 - - - F - - - NUDIX domain
NBPHLDOP_02197 4.68e-168 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NBPHLDOP_02198 9.57e-30 - - - - - - - -
NBPHLDOP_02199 1.09e-209 - - - S - - - zinc-ribbon domain
NBPHLDOP_02200 5.93e-262 pbpX - - V - - - Beta-lactamase
NBPHLDOP_02201 4.01e-240 ydbI - - K - - - AI-2E family transporter
NBPHLDOP_02202 4.31e-166 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
NBPHLDOP_02203 1.41e-85 gtcA2 - - S - - - Teichoic acid glycosylation protein
NBPHLDOP_02204 2.58e-226 - - - I - - - Diacylglycerol kinase catalytic domain
NBPHLDOP_02205 0.0 - 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NBPHLDOP_02206 3.51e-216 gbuC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
NBPHLDOP_02207 2.03e-189 gbuB - - E ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
NBPHLDOP_02208 9.19e-285 gbuA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
NBPHLDOP_02209 1.39e-176 sfsA - - S ko:K06206 - ko00000 Belongs to the SfsA family
NBPHLDOP_02210 2.6e-96 usp1 - - T - - - Universal stress protein family
NBPHLDOP_02211 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
NBPHLDOP_02212 7.73e-196 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NBPHLDOP_02213 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
NBPHLDOP_02214 7.09e-294 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
NBPHLDOP_02215 0.0 - 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NBPHLDOP_02216 2.16e-275 floL - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 SPFH domain / Band 7 family
NBPHLDOP_02217 7.64e-51 - - - - - - - -
NBPHLDOP_02218 2.23e-224 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
NBPHLDOP_02219 3.03e-227 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NBPHLDOP_02220 3.99e-278 aspC 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NBPHLDOP_02221 3.74e-69 - - - - - - - -
NBPHLDOP_02222 9.39e-166 WQ51_05710 - - S - - - Mitochondrial biogenesis AIM24
NBPHLDOP_02223 2.8e-94 - - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
NBPHLDOP_02224 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NBPHLDOP_02226 8.65e-182 mprF 2.3.2.3 - M ko:K07027,ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 lysyltransferase activity
NBPHLDOP_02228 6.9e-262 - - - S - - - Calcineurin-like phosphoesterase
NBPHLDOP_02229 6.42e-208 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
NBPHLDOP_02230 2.21e-220 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NBPHLDOP_02231 1.92e-283 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NBPHLDOP_02232 9.96e-212 ysdB - - S ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
NBPHLDOP_02233 2.61e-280 ysdA - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NBPHLDOP_02234 6.81e-86 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
NBPHLDOP_02235 5.32e-208 CcmA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NBPHLDOP_02236 1.28e-144 - - - I - - - ABC-2 family transporter protein
NBPHLDOP_02237 2.06e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 reductase
NBPHLDOP_02238 1.84e-260 ald1 1.4.1.1 - C ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
NBPHLDOP_02239 3.18e-240 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NBPHLDOP_02240 2.56e-162 - - - S - - - OPT oligopeptide transporter protein
NBPHLDOP_02241 1.06e-262 - - - S - - - OPT oligopeptide transporter protein
NBPHLDOP_02242 8.34e-83 - - - S - - - Coenzyme PQQ synthesis protein D (PqqD)
NBPHLDOP_02243 0.0 pepD3 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NBPHLDOP_02244 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
NBPHLDOP_02245 0.0 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
NBPHLDOP_02246 4.96e-127 - - - K ko:K18939 - ko00000,ko00002,ko03000 Bacterial regulatory proteins, tetR family
NBPHLDOP_02247 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NBPHLDOP_02248 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NBPHLDOP_02249 2.51e-200 bglG4 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
NBPHLDOP_02250 0.0 msbA9 - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
NBPHLDOP_02251 0.0 cydD1 - - CO ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
NBPHLDOP_02252 3.15e-98 - - - S - - - NusG domain II
NBPHLDOP_02253 2.48e-52 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
NBPHLDOP_02254 1.07e-203 - - - L - - - Integrase core domain
NBPHLDOP_02255 1.1e-155 - - - S - - - CRISPR-associated protein (Cas_Csn2)
NBPHLDOP_02256 2.84e-62 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NBPHLDOP_02257 2.98e-216 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NBPHLDOP_02258 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NBPHLDOP_02259 1.68e-183 - - - - - - - -
NBPHLDOP_02260 2.28e-276 - - - S - - - Membrane
NBPHLDOP_02261 6.76e-84 - - - S - - - Protein of unknown function (DUF1093)
NBPHLDOP_02262 6.43e-66 - - - - - - - -
NBPHLDOP_02263 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NBPHLDOP_02264 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NBPHLDOP_02265 2.5e-233 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
NBPHLDOP_02266 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
NBPHLDOP_02268 1.73e-305 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
NBPHLDOP_02269 1.86e-245 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NBPHLDOP_02270 6.98e-53 - - - - - - - -
NBPHLDOP_02271 1.22e-112 - - - - - - - -
NBPHLDOP_02272 6.71e-34 - - - - - - - -
NBPHLDOP_02273 1.72e-213 - - - EG - - - EamA-like transporter family
NBPHLDOP_02274 2.96e-145 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
NBPHLDOP_02275 9.59e-101 usp5 - - T - - - universal stress protein
NBPHLDOP_02276 3.25e-74 - - - K - - - Helix-turn-helix domain
NBPHLDOP_02277 6.37e-187 ptp3 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NBPHLDOP_02278 6.69e-287 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Domain of unknown function (DUF1730)
NBPHLDOP_02279 1.54e-84 - - - - - - - -
NBPHLDOP_02280 2.27e-247 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
NBPHLDOP_02281 7.09e-113 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
NBPHLDOP_02282 5.77e-93 adhR - - K - - - helix_turn_helix, mercury resistance
NBPHLDOP_02283 2.31e-110 - - - C - - - Flavodoxin
NBPHLDOP_02284 1.33e-253 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
NBPHLDOP_02285 2.75e-148 - - - GM - - - NmrA-like family
NBPHLDOP_02287 5.62e-132 - - - Q - - - methyltransferase
NBPHLDOP_02288 7.76e-143 - - - T - - - Sh3 type 3 domain protein
NBPHLDOP_02289 8.17e-153 - - - F - - - glutamine amidotransferase
NBPHLDOP_02290 6.35e-175 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2263)
NBPHLDOP_02291 0.0 yhdP - - S - - - Transporter associated domain
NBPHLDOP_02292 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
NBPHLDOP_02293 8.38e-80 - - - S - - - Domain of unknown function (DUF4811)
NBPHLDOP_02294 2.04e-129 maf - - D ko:K06287 - ko00000 nucleoside-triphosphate diphosphatase activity
NBPHLDOP_02295 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NBPHLDOP_02296 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NBPHLDOP_02297 0.0 ydaO - - E - - - amino acid
NBPHLDOP_02298 1.31e-75 - - - S - - - Domain of unknown function (DUF1827)
NBPHLDOP_02299 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NBPHLDOP_02300 1.7e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NBPHLDOP_02301 2.13e-143 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
NBPHLDOP_02302 1.01e-251 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NBPHLDOP_02303 1.2e-238 - - - - - - - -
NBPHLDOP_02304 5.93e-204 - - - V ko:K01990,ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NBPHLDOP_02305 4.97e-81 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
NBPHLDOP_02306 1.1e-151 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NBPHLDOP_02307 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
NBPHLDOP_02308 3.12e-68 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NBPHLDOP_02309 5.99e-243 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NBPHLDOP_02310 8.44e-130 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
NBPHLDOP_02311 3.82e-168 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
NBPHLDOP_02312 8.43e-96 - - - - - - - -
NBPHLDOP_02313 2.42e-117 - - - T - - - ECF transporter, substrate-specific component
NBPHLDOP_02314 4.68e-232 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
NBPHLDOP_02315 3.86e-185 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
NBPHLDOP_02316 1.49e-192 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NBPHLDOP_02317 7.92e-76 yabA - - L - - - Involved in initiation control of chromosome replication
NBPHLDOP_02318 2.28e-223 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NBPHLDOP_02319 1.14e-69 yaaQ - - S - - - Cyclic-di-AMP receptor
NBPHLDOP_02320 7.2e-151 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NBPHLDOP_02321 2.95e-46 - - - S - - - Protein of unknown function (DUF2508)
NBPHLDOP_02322 1.26e-139 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NBPHLDOP_02323 7e-49 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NBPHLDOP_02324 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NBPHLDOP_02325 4.38e-118 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NBPHLDOP_02326 9.05e-67 - - - - - - - -
NBPHLDOP_02327 8.53e-142 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
NBPHLDOP_02328 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NBPHLDOP_02329 3.3e-59 - - - - - - - -
NBPHLDOP_02330 1.49e-225 ccpB - - K - - - lacI family
NBPHLDOP_02331 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NBPHLDOP_02332 7.22e-207 - 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NBPHLDOP_02333 1.37e-74 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NBPHLDOP_02334 7.23e-108 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NBPHLDOP_02335 8.17e-285 mdtG - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
NBPHLDOP_02336 3.64e-201 - - - K - - - acetyltransferase
NBPHLDOP_02337 3.45e-87 - - - - - - - -
NBPHLDOP_02338 4.33e-280 yceI - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
NBPHLDOP_02339 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NBPHLDOP_02340 1.89e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NBPHLDOP_02341 6.87e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NBPHLDOP_02342 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
NBPHLDOP_02343 0.0 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
NBPHLDOP_02344 4.39e-89 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
NBPHLDOP_02345 7.84e-123 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Cobalamin adenosyltransferase
NBPHLDOP_02346 9.98e-128 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF transporter, substrate-specific component
NBPHLDOP_02347 4.31e-83 - - - S - - - Domain of unknown function (DUF4430)
NBPHLDOP_02348 0.0 rtpR 1.17.4.2 - F ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 ribonucleoside-triphosphate reductase activity
NBPHLDOP_02349 3.77e-102 - - - F - - - Nucleoside 2-deoxyribosyltransferase
NBPHLDOP_02350 1.71e-205 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NBPHLDOP_02351 2.29e-130 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
NBPHLDOP_02352 2.09e-30 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NBPHLDOP_02353 4.4e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NBPHLDOP_02354 1.13e-220 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
NBPHLDOP_02355 2.44e-216 menA 2.5.1.74 - M ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
NBPHLDOP_02356 2.2e-252 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NBPHLDOP_02357 4.15e-188 cad - - S ko:K20379 ko02024,map02024 ko00000,ko00001 FMN_bind
NBPHLDOP_02358 0.0 ndh 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NBPHLDOP_02359 4.76e-105 - - - S - - - NusG domain II
NBPHLDOP_02360 1.03e-127 hepA 2.5.1.30 - S ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase component I
NBPHLDOP_02361 3.28e-232 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NBPHLDOP_02363 2.3e-158 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 Rossmann-like domain
NBPHLDOP_02364 3.12e-250 XK27_00915 - - C - - - Luciferase-like monooxygenase
NBPHLDOP_02366 5.04e-127 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
NBPHLDOP_02367 9.39e-183 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NBPHLDOP_02368 2.39e-98 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NBPHLDOP_02369 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NBPHLDOP_02370 0.0 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
NBPHLDOP_02371 2.65e-139 - - - - - - - -
NBPHLDOP_02373 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NBPHLDOP_02374 3.45e-239 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
NBPHLDOP_02375 3.15e-154 rpiA1 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
NBPHLDOP_02376 1.73e-182 - - - K - - - SIS domain
NBPHLDOP_02377 8.77e-147 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
NBPHLDOP_02378 2.27e-225 - - - S - - - Membrane
NBPHLDOP_02379 9.18e-83 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
NBPHLDOP_02380 3.39e-227 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NBPHLDOP_02381 6.11e-186 natA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NBPHLDOP_02382 1.72e-169 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NBPHLDOP_02383 5.36e-172 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NBPHLDOP_02384 5.17e-290 inlJ - - M - - - MucBP domain
NBPHLDOP_02385 5.79e-172 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NBPHLDOP_02386 6.18e-206 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NBPHLDOP_02387 2.54e-211 - - - K - - - sequence-specific DNA binding
NBPHLDOP_02388 5.49e-261 yacL - - S - - - domain protein
NBPHLDOP_02389 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NBPHLDOP_02390 4.85e-130 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTPase
NBPHLDOP_02391 1.22e-67 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
NBPHLDOP_02392 5.93e-93 - - - S - - - Protein of unknown function (DUF805)
NBPHLDOP_02393 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
NBPHLDOP_02394 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
NBPHLDOP_02395 1.97e-256 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
NBPHLDOP_02396 3.84e-279 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NBPHLDOP_02397 5.79e-214 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NBPHLDOP_02398 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
NBPHLDOP_02399 0.0 ppdK 2.7.9.1 - G ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the PEP-utilizing enzyme family
NBPHLDOP_02400 3.68e-136 ccpN - - K - - - Domain in cystathionine beta-synthase and other proteins.
NBPHLDOP_02401 1.19e-158 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NBPHLDOP_02402 4.71e-263 - - - S - - - Bacterial low temperature requirement A protein (LtrA)
NBPHLDOP_02403 5.25e-61 - - - - - - - -
NBPHLDOP_02404 2.08e-265 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
NBPHLDOP_02405 1.59e-28 yhjA - - K - - - CsbD-like
NBPHLDOP_02406 2.28e-293 - 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
NBPHLDOP_02407 3.02e-275 - - - EGP ko:K08196 - ko00000,ko02000 Major Facilitator
NBPHLDOP_02408 1.45e-180 udp 2.4.2.3 - F ko:K00757 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Phosphorylase superfamily
NBPHLDOP_02409 6.53e-272 - - - EGP ko:K08196 - ko00000,ko02000 Major Facilitator
NBPHLDOP_02410 9.8e-247 - - - KT ko:K02647 - ko00000,ko03000 Purine catabolism regulatory protein-like family
NBPHLDOP_02412 1.5e-44 - - - - - - - -
NBPHLDOP_02413 6.09e-53 - - - - - - - -
NBPHLDOP_02414 4.23e-287 - - - EGP - - - Transmembrane secretion effector
NBPHLDOP_02415 5.68e-280 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NBPHLDOP_02416 4.65e-192 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NBPHLDOP_02418 2.57e-55 - - - - - - - -
NBPHLDOP_02419 1.38e-295 - - - S - - - Membrane
NBPHLDOP_02420 2.81e-192 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
NBPHLDOP_02421 0.0 - - - M - - - Cna protein B-type domain
NBPHLDOP_02422 5.21e-310 - - - - - - - -
NBPHLDOP_02423 0.0 - - - M - - - domain protein
NBPHLDOP_02424 8.99e-133 - - - - - - - -
NBPHLDOP_02425 9.31e-294 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
NBPHLDOP_02426 1.2e-263 - - - S - - - Protein of unknown function (DUF2974)
NBPHLDOP_02427 3.71e-146 - - - K - - - Helix-turn-helix XRE-family like proteins
NBPHLDOP_02428 8.68e-74 padR - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
NBPHLDOP_02429 1.93e-80 - - - - - - - -
NBPHLDOP_02430 2.2e-178 - - - - - - - -
NBPHLDOP_02431 6.69e-61 - - - S - - - Enterocin A Immunity
NBPHLDOP_02432 2.22e-60 - - - S - - - Enterocin A Immunity
NBPHLDOP_02433 3.61e-61 spiA - - K - - - TRANSCRIPTIONal
NBPHLDOP_02434 0.0 - - - S - - - Putative threonine/serine exporter
NBPHLDOP_02436 5.75e-72 - - - - - - - -
NBPHLDOP_02437 5.05e-313 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
NBPHLDOP_02438 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NBPHLDOP_02439 2.95e-50 - - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 protein secretion by the type I secretion system
NBPHLDOP_02442 1.35e-174 - 2.7.13.3 - T ko:K02476,ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
NBPHLDOP_02443 7.99e-184 plnD - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NBPHLDOP_02445 1.27e-15 - - - - - - - -
NBPHLDOP_02449 1.66e-188 - - - S - - - CAAX protease self-immunity
NBPHLDOP_02451 5.62e-75 - - - - - - - -
NBPHLDOP_02452 1.66e-05 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
NBPHLDOP_02453 1.18e-72 - - - S - - - Enterocin A Immunity
NBPHLDOP_02454 7.86e-138 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
NBPHLDOP_02458 8.37e-231 ydhF - - S - - - Aldo keto reductase
NBPHLDOP_02459 3.51e-166 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NBPHLDOP_02460 1.98e-278 yqiG - - C - - - Oxidoreductase
NBPHLDOP_02461 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NBPHLDOP_02462 1.88e-174 - - - - - - - -
NBPHLDOP_02463 6.42e-28 - - - - - - - -
NBPHLDOP_02464 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NBPHLDOP_02465 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
NBPHLDOP_02466 1.14e-72 - - - - - - - -
NBPHLDOP_02467 4.42e-306 - - - EGP - - - Major Facilitator Superfamily
NBPHLDOP_02468 0.0 sufI - - Q - - - Multicopper oxidase
NBPHLDOP_02469 1.53e-35 - - - - - - - -
NBPHLDOP_02470 2.22e-144 - - - P - - - Cation efflux family
NBPHLDOP_02471 1.23e-69 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
NBPHLDOP_02472 6.58e-226 mntA - - P ko:K19975,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NBPHLDOP_02473 1.07e-187 mtsB - - U ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
NBPHLDOP_02474 3.38e-170 - 3.6.3.35 - P ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NBPHLDOP_02475 0.0 aldA 1.2.1.21, 1.2.1.22 - C ko:K07248 ko00620,ko00630,ko01120,map00620,map00630,map01120 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family
NBPHLDOP_02476 2.9e-56 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NBPHLDOP_02477 4.82e-226 - - - L - - - Transposase and inactivated derivatives, IS30 family
NBPHLDOP_02478 6.75e-215 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NBPHLDOP_02479 3.3e-151 - - - GM - - - NmrA-like family
NBPHLDOP_02480 5.94e-148 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
NBPHLDOP_02481 7.04e-102 - - - - - - - -
NBPHLDOP_02482 0.0 - - - M - - - domain protein
NBPHLDOP_02483 1.26e-212 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NBPHLDOP_02484 2.1e-27 - - - - - - - -
NBPHLDOP_02485 8.26e-104 - - - - - - - -
NBPHLDOP_02487 0.0 - - - L - - - A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NBPHLDOP_02488 6.39e-73 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NBPHLDOP_02489 1.58e-91 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NBPHLDOP_02491 1.72e-49 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 phosphopyruvate hydratase activity
NBPHLDOP_02492 1.99e-212 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
NBPHLDOP_02493 1.49e-178 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NBPHLDOP_02494 2.46e-174 phnB - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NBPHLDOP_02495 1.97e-188 ptxC - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NBPHLDOP_02496 4.82e-226 - - - L - - - Transposase and inactivated derivatives, IS30 family
NBPHLDOP_02497 6.58e-227 ssuA - - P ko:K02051,ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 NMT1-like family
NBPHLDOP_02498 0.0 - 6.2.1.48 - IQ ko:K02182 - ko00000,ko01000 AMP-binding enzyme C-terminal domain
NBPHLDOP_02499 4.88e-302 - - - I - - - Acyltransferase family
NBPHLDOP_02500 1.17e-154 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
NBPHLDOP_02501 1.02e-192 ssuC - - U ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NBPHLDOP_02502 7.94e-175 XK27_06950 - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NBPHLDOP_02503 2.2e-175 XK27_06945 - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NBPHLDOP_02504 2.04e-175 - - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NBPHLDOP_02505 1.17e-123 - - - S - - - Protein of unknown function (DUF2785)
NBPHLDOP_02506 1.28e-12 - - - S - - - Protein of unknown function (DUF2785)
NBPHLDOP_02507 9.26e-146 - - - - - - - -
NBPHLDOP_02508 1.29e-74 - - - - - - - -
NBPHLDOP_02509 8.98e-86 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
NBPHLDOP_02510 2.98e-104 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NBPHLDOP_02511 1.46e-140 - - - K - - - Bacterial regulatory proteins, tetR family
NBPHLDOP_02512 2.61e-238 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NBPHLDOP_02513 3.14e-165 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NBPHLDOP_02514 1.5e-44 - - - - - - - -
NBPHLDOP_02515 3.24e-171 tipA - - K - - - TipAS antibiotic-recognition domain
NBPHLDOP_02516 1.39e-178 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NBPHLDOP_02517 1.13e-181 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NBPHLDOP_02518 4.71e-203 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NBPHLDOP_02519 1.15e-197 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NBPHLDOP_02520 9.02e-154 - - - - - - - -
NBPHLDOP_02521 5.46e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
NBPHLDOP_02522 1.26e-218 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NBPHLDOP_02523 3.82e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NBPHLDOP_02524 5.37e-76 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NBPHLDOP_02525 6.38e-20 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
NBPHLDOP_02526 4.15e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NBPHLDOP_02527 1.11e-156 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NBPHLDOP_02528 4.24e-305 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NBPHLDOP_02529 4.07e-92 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
NBPHLDOP_02530 2.6e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
NBPHLDOP_02531 5.74e-109 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NBPHLDOP_02532 1.62e-76 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NBPHLDOP_02533 2.61e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NBPHLDOP_02534 1.32e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NBPHLDOP_02535 8.67e-124 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NBPHLDOP_02536 4.1e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NBPHLDOP_02537 1.73e-77 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NBPHLDOP_02538 5.93e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NBPHLDOP_02539 3.55e-33 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
NBPHLDOP_02540 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NBPHLDOP_02541 2.8e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NBPHLDOP_02542 4.5e-73 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NBPHLDOP_02543 5.26e-63 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NBPHLDOP_02544 7.23e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NBPHLDOP_02545 1.02e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NBPHLDOP_02546 1.98e-140 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
NBPHLDOP_02547 4.01e-146 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NBPHLDOP_02548 4.46e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
NBPHLDOP_02549 3.63e-90 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
NBPHLDOP_02550 2.38e-138 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 C-terminal domain of 1-Cys peroxiredoxin
NBPHLDOP_02551 3.54e-257 - - - K - - - WYL domain
NBPHLDOP_02552 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NBPHLDOP_02553 2.4e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NBPHLDOP_02554 1.11e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NBPHLDOP_02555 0.0 - - - M - - - domain protein
NBPHLDOP_02556 1.47e-46 - 3.4.23.43 - - ko:K02236 - ko00000,ko00002,ko01000,ko02044 -
NBPHLDOP_02557 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NBPHLDOP_02558 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NBPHLDOP_02559 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NBPHLDOP_02560 4.32e-105 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
NBPHLDOP_02571 5.19e-90 - - - S - - - COG NOG38524 non supervised orthologous group
NBPHLDOP_02574 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
NBPHLDOP_02575 5.32e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NBPHLDOP_02576 5.11e-209 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NBPHLDOP_02577 1.59e-210 - - - S - - - WxL domain surface cell wall-binding
NBPHLDOP_02579 4.22e-244 - - - S - - - Bacterial protein of unknown function (DUF916)
NBPHLDOP_02580 1.18e-250 - - - S - - - Protein of unknown function C-terminal (DUF3324)
NBPHLDOP_02581 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
NBPHLDOP_02582 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NBPHLDOP_02583 1.38e-125 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
NBPHLDOP_02584 2.68e-310 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NBPHLDOP_02585 1.17e-105 yabR - - J ko:K07571 - ko00000 RNA binding
NBPHLDOP_02586 3.35e-87 divIC - - D ko:K05589,ko:K13052 - ko00000,ko03036 cell cycle
NBPHLDOP_02587 1.99e-53 yabO - - J - - - S4 domain protein
NBPHLDOP_02588 0.0 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
NBPHLDOP_02589 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NBPHLDOP_02590 4.28e-131 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NBPHLDOP_02591 5.04e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NBPHLDOP_02592 0.0 - - - S - - - Putative peptidoglycan binding domain
NBPHLDOP_02593 4.14e-126 padR - - K - - - Transcriptional regulator PadR-like family
NBPHLDOP_02594 0.0 - - - S ko:K01421 - ko00000 ABC-2 family transporter protein
NBPHLDOP_02595 2.45e-150 - - - S - - - Flavodoxin-like fold
NBPHLDOP_02596 3.08e-124 - - - S - - - (CBS) domain
NBPHLDOP_02597 1.02e-169 yciB - - M - - - ErfK YbiS YcfS YnhG
NBPHLDOP_02598 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
NBPHLDOP_02599 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 GXGXG motif
NBPHLDOP_02600 1.39e-112 queT - - S - - - QueT transporter
NBPHLDOP_02601 5.68e-83 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
NBPHLDOP_02602 1.9e-43 - - - - - - - -
NBPHLDOP_02603 2.8e-278 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NBPHLDOP_02604 2.63e-82 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NBPHLDOP_02605 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NBPHLDOP_02606 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NBPHLDOP_02607 2.07e-188 - - - - - - - -
NBPHLDOP_02608 3.18e-161 - - - S - - - Tetratricopeptide repeat
NBPHLDOP_02609 2.61e-163 - - - - - - - -
NBPHLDOP_02610 2.29e-87 - - - - - - - -
NBPHLDOP_02611 2.28e-57 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
NBPHLDOP_02612 2.33e-300 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NBPHLDOP_02613 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NBPHLDOP_02614 3.42e-202 ybbB - - S - - - Protein of unknown function (DUF1211)
NBPHLDOP_02615 1.15e-111 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NBPHLDOP_02616 4.23e-104 ywiB - - S - - - Domain of unknown function (DUF1934)
NBPHLDOP_02617 2.07e-202 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
NBPHLDOP_02618 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
NBPHLDOP_02619 3.75e-40 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 - L ko:K01515,ko:K03574,ko:K11991 ko00230,map00230 ko00000,ko00001,ko01000,ko03016,ko03400 nUDIX hydrolase
NBPHLDOP_02620 2.14e-237 - - - S - - - DUF218 domain
NBPHLDOP_02621 1.31e-77 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NBPHLDOP_02622 1.68e-104 - - - E - - - glutamate:sodium symporter activity
NBPHLDOP_02623 1.32e-74 nudA - - S - - - ASCH
NBPHLDOP_02624 1.81e-35 - - - - - - - -
NBPHLDOP_02625 2.2e-225 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NBPHLDOP_02626 3.29e-299 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NBPHLDOP_02627 1.79e-286 ysaA - - V - - - RDD family
NBPHLDOP_02628 1.01e-193 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
NBPHLDOP_02629 2.24e-155 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NBPHLDOP_02630 8.36e-158 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
NBPHLDOP_02631 1.4e-205 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
NBPHLDOP_02632 6.63e-232 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NBPHLDOP_02633 4.13e-51 veg - - S - - - Biofilm formation stimulator VEG
NBPHLDOP_02634 1.75e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NBPHLDOP_02635 6.78e-130 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NBPHLDOP_02636 9.1e-190 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
NBPHLDOP_02637 2.57e-104 manR 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 - G ko:K02538,ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 phosphoenolpyruvate-dependent sugar phosphotransferase system
NBPHLDOP_02638 1.35e-239 lacD 4.1.2.40 - G ko:K01635 ko00052,ko01100,ko02024,map00052,map01100,map02024 ko00000,ko00001,ko01000 Belongs to the aldolase LacD family
NBPHLDOP_02639 1.49e-221 yqhA - - G - - - Aldose 1-epimerase
NBPHLDOP_02640 8.65e-162 - - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NBPHLDOP_02641 5.31e-211 - - - T - - - GHKL domain
NBPHLDOP_02642 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
NBPHLDOP_02643 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
NBPHLDOP_02644 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NBPHLDOP_02645 4.11e-223 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
NBPHLDOP_02646 1.25e-197 yunF - - F - - - Protein of unknown function DUF72
NBPHLDOP_02647 1.09e-118 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
NBPHLDOP_02648 3.11e-218 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
NBPHLDOP_02649 9.14e-139 yiiE - - S - - - Protein of unknown function (DUF1211)
NBPHLDOP_02650 5.67e-165 cobB - - K ko:K12410 - ko00000,ko01000 Sir2 family
NBPHLDOP_02651 6.41e-24 - - - - - - - -
NBPHLDOP_02652 5.59e-220 - - - - - - - -
NBPHLDOP_02654 3.21e-125 yxkA - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
NBPHLDOP_02655 4.7e-50 - - - - - - - -
NBPHLDOP_02656 4.34e-196 ypuA - - S - - - Protein of unknown function (DUF1002)
NBPHLDOP_02657 2.57e-223 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
NBPHLDOP_02658 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NBPHLDOP_02659 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
NBPHLDOP_02660 1.74e-224 ydhF - - S - - - Aldo keto reductase
NBPHLDOP_02662 5.94e-198 - - - Q - - - Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
NBPHLDOP_02663 2.76e-120 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
NBPHLDOP_02664 9.66e-307 dinF - - V - - - MatE
NBPHLDOP_02665 8.78e-158 - - - S ko:K06872 - ko00000 TPM domain
NBPHLDOP_02666 8.42e-135 lemA - - S ko:K03744 - ko00000 LemA family
NBPHLDOP_02667 1.48e-246 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NBPHLDOP_02668 5.94e-262 - - - V - - - efflux transmembrane transporter activity
NBPHLDOP_02669 1.95e-225 - - - V - - - ATPases associated with a variety of cellular activities
NBPHLDOP_02671 0.0 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
NBPHLDOP_02672 6.07e-225 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NBPHLDOP_02673 0.0 choS - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NBPHLDOP_02675 0.0 - - - L - - - DNA helicase
NBPHLDOP_02676 2.93e-195 rlrG - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
NBPHLDOP_02677 1.6e-222 ydiA - - P ko:K11041 ko05150,map05150 ko00000,ko00001,ko02042 Voltage-dependent anion channel
NBPHLDOP_02678 5.68e-148 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NBPHLDOP_02680 3.62e-149 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NBPHLDOP_02681 1.91e-93 - - - K - - - MarR family
NBPHLDOP_02682 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC
NBPHLDOP_02683 7.61e-247 yghZ - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
NBPHLDOP_02684 5.86e-187 - - - S - - - hydrolase
NBPHLDOP_02685 4.04e-79 - - - - - - - -
NBPHLDOP_02686 4.9e-17 - - - - - - - -
NBPHLDOP_02687 3.55e-146 - - - S - - - Protein of unknown function (DUF1275)
NBPHLDOP_02688 1.63e-163 gpmB - - G ko:K15640 - ko00000 Phosphoglycerate mutase family
NBPHLDOP_02689 5.08e-197 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
NBPHLDOP_02690 1.38e-117 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NBPHLDOP_02691 1.08e-213 - - - K - - - LysR substrate binding domain
NBPHLDOP_02692 6.04e-291 - - - EK - - - Aminotransferase, class I
NBPHLDOP_02693 0.0 - - - EGP - - - Major Facilitator
NBPHLDOP_02694 8.61e-143 - - - K - - - Bacterial regulatory proteins, tetR family
NBPHLDOP_02695 2.13e-246 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NBPHLDOP_02696 4.42e-154 ydfK - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
NBPHLDOP_02697 5.24e-116 - - - - - - - -
NBPHLDOP_02698 0.0 fruC 2.7.1.202 - GT ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBPHLDOP_02699 1.88e-223 fruK-1 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
NBPHLDOP_02700 2.36e-167 rpl - - K - - - Helix-turn-helix domain, rpiR family
NBPHLDOP_02701 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NBPHLDOP_02702 5.44e-175 - - - K - - - UTRA domain
NBPHLDOP_02703 0.0 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 Alpha-L-fucosidase
NBPHLDOP_02704 1.72e-216 - 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NBPHLDOP_02705 9.8e-169 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
NBPHLDOP_02706 2.84e-192 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
NBPHLDOP_02707 5.34e-64 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
NBPHLDOP_02708 5.16e-66 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NBPHLDOP_02709 0.0 bgl 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NBPHLDOP_02710 1.77e-203 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
NBPHLDOP_02711 0.0 - - - S ko:K09704 - ko00000 Metal-independent alpha-mannosidase (GH125)
NBPHLDOP_02712 0.0 mngB 3.2.1.170 GH38 G ko:K15524 - ko00000,ko01000 Glycosyl hydrolases family 38 N-terminal domain
NBPHLDOP_02713 1.54e-307 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NBPHLDOP_02714 1.1e-172 - - - K ko:K03492 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
NBPHLDOP_02716 3.7e-176 - 4.1.2.17 - G ko:K01628 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Class II Aldolase and Adducin N-terminal domain
NBPHLDOP_02718 0.0 pts36C - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NBPHLDOP_02719 4.54e-70 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NBPHLDOP_02720 1.89e-110 pts36A 2.7.1.200 - G ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBPHLDOP_02721 1.62e-186 rdrB - - K ko:K02444,ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
NBPHLDOP_02722 4.06e-209 - - - J - - - Methyltransferase domain
NBPHLDOP_02723 0.0 - 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NBPHLDOP_02726 3.65e-46 - - - M - - - Right handed beta helix region
NBPHLDOP_02727 0.0 - - - M - - - Right handed beta helix region
NBPHLDOP_02728 3.76e-96 - - - - - - - -
NBPHLDOP_02729 0.0 - - - M - - - Heparinase II/III N-terminus
NBPHLDOP_02731 5.89e-108 - - - G ko:K02744 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NBPHLDOP_02732 8.63e-185 agaD - - G ko:K02747 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
NBPHLDOP_02733 6.84e-186 - - - G ko:K02746 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
NBPHLDOP_02734 1.72e-114 - - - G ko:K02745 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NBPHLDOP_02735 8.01e-301 ugl 3.2.1.180 GH88 S ko:K18581 - ko00000,ko01000 Glycosyl Hydrolase Family 88
NBPHLDOP_02736 1.65e-205 - - - S - - - Psort location Cytoplasmic, score
NBPHLDOP_02737 1.1e-179 - - - K - - - Bacterial transcriptional regulator
NBPHLDOP_02738 4.76e-212 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NBPHLDOP_02739 6.38e-193 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NBPHLDOP_02740 2.32e-153 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
NBPHLDOP_02741 3.36e-248 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 pfkB family carbohydrate kinase
NBPHLDOP_02742 4.7e-156 alkD - - L - - - DNA alkylation repair enzyme
NBPHLDOP_02743 8.71e-164 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NBPHLDOP_02744 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NBPHLDOP_02745 2.46e-221 ykoT - - M - - - Glycosyl transferase family 2
NBPHLDOP_02746 1.56e-154 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 phosphatase
NBPHLDOP_02747 8.38e-152 - - - S ko:K03975 - ko00000 SNARE-like domain protein
NBPHLDOP_02748 1.8e-316 kinE - - T - - - Histidine kinase
NBPHLDOP_02749 1.97e-162 llrE - - K - - - Transcriptional regulatory protein, C terminal
NBPHLDOP_02750 0.0 - 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
NBPHLDOP_02751 0.0 - 2.7.1.199, 2.7.1.208 - G ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
NBPHLDOP_02752 0.0 hylB 4.2.2.1 PL8 N ko:K01727 - ko00000,ko01000 Polysaccharide lyase family 8, N terminal alpha-helical domain
NBPHLDOP_02753 0.0 - - - - - - - -
NBPHLDOP_02754 1.72e-242 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
NBPHLDOP_02755 4.77e-89 - - - - - - - -
NBPHLDOP_02757 3.3e-144 - - - - - - - -
NBPHLDOP_02758 6.42e-112 - - - - - - - -
NBPHLDOP_02759 2.49e-182 - - - K - - - M protein trans-acting positive regulator
NBPHLDOP_02760 2.5e-174 - - - L - - - Helix-turn-helix domain
NBPHLDOP_02761 2.46e-215 - - - L ko:K07497 - ko00000 hmm pf00665
NBPHLDOP_02762 2.49e-167 mga - - K ko:K02538 - ko00000,ko03000 transcriptional antiterminator
NBPHLDOP_02763 3.39e-156 - - - K - - - Helix-turn-helix domain, rpiR family
NBPHLDOP_02764 2.57e-109 ptbA 2.7.1.208 - G ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NBPHLDOP_02765 3.33e-265 - - - S - - - DUF218 domain
NBPHLDOP_02766 5.63e-177 - 4.1.2.14 - S ko:K17463 ko00030,ko01100,ko01120,map00030,map01100,map01120 ko00000,ko00001,ko00002,ko01000 KDGP aldolase
NBPHLDOP_02767 2.62e-261 selA 2.9.1.1 - H ko:K01042 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko01000 L-seryl-tRNA selenium transferase
NBPHLDOP_02768 3.82e-278 dho 3.5.2.3 - S ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Amidohydrolase family
NBPHLDOP_02769 3.79e-155 - - - S - - - Domain of unknown function (DUF4310)
NBPHLDOP_02770 4.1e-177 - - - S - - - Domain of unknown function (DUF4311)
NBPHLDOP_02771 1.1e-76 - - - S - - - Domain of unknown function (DUF4312)
NBPHLDOP_02772 2.66e-53 - - - S - - - Glycine-rich SFCGS
NBPHLDOP_02773 1.82e-74 - - - S - - - PRD domain
NBPHLDOP_02774 0.0 - - - K - - - Mga helix-turn-helix domain
NBPHLDOP_02775 8.74e-161 - - - H - - - Pfam:Transaldolase
NBPHLDOP_02776 2.24e-84 - 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
NBPHLDOP_02777 3.58e-262 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
NBPHLDOP_02778 5.81e-131 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
NBPHLDOP_02779 2.63e-115 srlM1 - - K - - - Glucitol operon activator protein (GutM)
NBPHLDOP_02780 0.0 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
NBPHLDOP_02781 4.13e-185 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
NBPHLDOP_02782 1.57e-177 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NBPHLDOP_02783 2.51e-194 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NBPHLDOP_02784 1.53e-212 sga 5.1.3.22 - G ko:K03079 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Xylose isomerase-like TIM barrel
NBPHLDOP_02785 8.64e-178 - - - K - - - DeoR C terminal sensor domain
NBPHLDOP_02786 3.17e-149 ulaD 4.1.1.85, 4.1.2.43 - G ko:K03078,ko:K08093 ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Orotidine 5'-phosphate decarboxylase / HUMPS family
NBPHLDOP_02787 3.36e-61 sgaB 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NBPHLDOP_02788 0.0 sgaT - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NBPHLDOP_02789 4.89e-105 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBPHLDOP_02790 4.59e-275 ulaG - - S ko:K03476 ko00053,ko01100,ko01120,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Beta-lactamase superfamily domain
NBPHLDOP_02791 2.92e-162 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NBPHLDOP_02792 1.1e-254 - 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
NBPHLDOP_02793 4.26e-91 - - - G - - - DeoC/LacD family aldolase
NBPHLDOP_02794 3.93e-58 - 4.1.2.13 - G ko:K11645 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 lyase activity
NBPHLDOP_02795 1.15e-154 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
NBPHLDOP_02796 1.29e-201 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
NBPHLDOP_02797 1.95e-172 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
NBPHLDOP_02798 1.62e-106 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NBPHLDOP_02799 1.23e-95 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NBPHLDOP_02800 3.07e-263 - 1.1.1.405 - E ko:K05352 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
NBPHLDOP_02801 1.67e-173 - - - K - - - DeoR C terminal sensor domain
NBPHLDOP_02802 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
NBPHLDOP_02803 5.08e-207 - - - GK - - - ROK family
NBPHLDOP_02804 5.46e-233 asnA2 3.5.1.1 - E ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
NBPHLDOP_02805 0.0 - - - E - - - Peptidase family M20/M25/M40
NBPHLDOP_02806 2.59e-170 - - - K ko:K03710 - ko00000,ko03000 UTRA
NBPHLDOP_02807 0.0 - 4.1.1.12 - E ko:K09758 ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230 ko00000,ko00001,ko01000 Aminotransferase
NBPHLDOP_02808 1.67e-272 - - - EGP - - - Transporter, major facilitator family protein
NBPHLDOP_02809 2.07e-265 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 Alpha-L-fucosidase
NBPHLDOP_02810 1.07e-93 - - - S - - - Domain of unknown function (DUF4428)
NBPHLDOP_02811 0.0 - 2.7.1.17, 2.7.1.53 - G ko:K00854,ko:K00880 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the FGGY kinase family
NBPHLDOP_02812 6.91e-261 - 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
NBPHLDOP_02813 1.34e-199 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
NBPHLDOP_02814 3.52e-176 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
NBPHLDOP_02815 5.64e-107 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NBPHLDOP_02816 1.03e-92 ahaA 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NBPHLDOP_02817 0.0 - - - K ko:K03491 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBPHLDOP_02818 1.72e-242 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
NBPHLDOP_02819 2.4e-20 licR - - G ko:K03491 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBPHLDOP_02820 3.46e-207 - - - G - - - Fructose-bisphosphate aldolase class-II
NBPHLDOP_02821 0.0 - - - G - - - FGGY family of carbohydrate kinases, C-terminal domain
NBPHLDOP_02822 0.0 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NBPHLDOP_02823 9.89e-64 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NBPHLDOP_02824 6.52e-103 - 2.7.1.200 - GT ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBPHLDOP_02825 2.63e-206 - - - G - - - Fructose-bisphosphate aldolase class-II
NBPHLDOP_02826 1.97e-173 farR - - K - - - Helix-turn-helix domain
NBPHLDOP_02827 1.66e-116 - - - M ko:K03828 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NBPHLDOP_02828 2.16e-132 laaE - - K - - - Transcriptional regulator PadR-like family
NBPHLDOP_02829 0.0 chaT1 - - U ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
NBPHLDOP_02830 2.75e-116 - - - K - - - Acetyltransferase (GNAT) domain
NBPHLDOP_02831 3.62e-121 yveA - - Q - - - Isochorismatase family
NBPHLDOP_02832 9.53e-76 ps105 - - - - - - -
NBPHLDOP_02834 5.38e-125 - - - K - - - Helix-turn-helix domain
NBPHLDOP_02835 3.37e-140 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
NBPHLDOP_02836 3.87e-97 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NBPHLDOP_02837 0.0 ugpB - - G ko:K05813 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NBPHLDOP_02838 2.92e-192 ugpE - - G ko:K05815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NBPHLDOP_02839 3.19e-211 - - - P ko:K05814 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type sugar transport systems, permease components
NBPHLDOP_02840 7.33e-271 ugpC 3.6.3.20 - E ko:K05816,ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the ABC transporter superfamily
NBPHLDOP_02841 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NBPHLDOP_02842 1.89e-139 pncA - - Q - - - Isochorismatase family
NBPHLDOP_02843 3.28e-175 - - - F - - - NUDIX domain
NBPHLDOP_02844 1.45e-187 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
NBPHLDOP_02845 9.61e-247 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
NBPHLDOP_02846 1.13e-251 - - - V - - - Beta-lactamase
NBPHLDOP_02847 1.43e-197 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NBPHLDOP_02848 1.58e-211 - - - K - - - Helix-turn-helix domain, rpiR family
NBPHLDOP_02849 1.67e-105 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NBPHLDOP_02850 1.56e-192 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
NBPHLDOP_02851 8.76e-177 XK27_08455 - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
NBPHLDOP_02852 1.06e-259 - - - S - - - endonuclease exonuclease phosphatase family protein
NBPHLDOP_02853 2.28e-220 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
NBPHLDOP_02854 1.18e-134 - - - Q - - - Methyltransferase
NBPHLDOP_02855 2.16e-68 sugE - - U ko:K11741 - ko00000,ko02000 Multidrug resistance protein
NBPHLDOP_02856 2.69e-22 - - - - - - - -
NBPHLDOP_02857 2.45e-59 - - - I - - - carboxylic ester hydrolase activity
NBPHLDOP_02858 3.22e-65 - - - S - - - alpha beta
NBPHLDOP_02859 3.81e-84 - - - S - - - Protein of unknown function (DUF1648)
NBPHLDOP_02860 5.44e-174 - - - S - - - -acetyltransferase
NBPHLDOP_02861 1.17e-121 yfbM - - K - - - FR47-like protein
NBPHLDOP_02862 2.42e-122 - - - E - - - HAD-hyrolase-like
NBPHLDOP_02863 4.93e-244 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
NBPHLDOP_02864 8.05e-180 ptp1 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NBPHLDOP_02865 1.7e-122 - - - K - - - Acetyltransferase (GNAT) domain
NBPHLDOP_02866 5.73e-110 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NBPHLDOP_02867 2.61e-105 - - - K ko:K03830 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NBPHLDOP_02868 8.99e-300 - - - K - - - Putative DNA-binding domain
NBPHLDOP_02869 1.06e-163 tnp1216 - - L ko:K07498 - ko00000 DDE domain
NBPHLDOP_02870 1.74e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NBPHLDOP_02871 3.81e-254 ysdE - - P - - - Citrate transporter
NBPHLDOP_02872 8.69e-91 - - - - - - - -
NBPHLDOP_02873 0.0 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
NBPHLDOP_02874 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NBPHLDOP_02876 2.96e-134 - - - - - - - -
NBPHLDOP_02877 0.0 cadA - - P - - - P-type ATPase
NBPHLDOP_02878 2.19e-100 hsp3 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NBPHLDOP_02879 2.35e-92 - - - S - - - Iron-sulphur cluster biosynthesis
NBPHLDOP_02880 1.7e-284 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
NBPHLDOP_02882 4.32e-196 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
NBPHLDOP_02883 1.05e-182 yycI - - S - - - YycH protein
NBPHLDOP_02884 0.0 yycH - - S - - - YycH protein
NBPHLDOP_02885 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NBPHLDOP_02886 3.03e-168 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NBPHLDOP_02887 1.06e-157 - 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Alpha/beta hydrolase family
NBPHLDOP_02888 0.0 arpJ - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
NBPHLDOP_02889 1.39e-299 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
NBPHLDOP_02890 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
NBPHLDOP_02891 4.78e-273 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
NBPHLDOP_02892 9.09e-97 - - - S - - - Domain of unknown function (DUF3284)
NBPHLDOP_02893 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NBPHLDOP_02894 1.97e-168 gntR - - K ko:K03489 - ko00000,ko03000 UTRA
NBPHLDOP_02895 5.01e-69 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NBPHLDOP_02896 8.36e-72 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
NBPHLDOP_02897 1.82e-140 yokL3 - - J - - - Acetyltransferase (GNAT) domain
NBPHLDOP_02898 1.84e-110 - - - F - - - NUDIX domain
NBPHLDOP_02899 1.35e-119 - - - S - - - AAA domain
NBPHLDOP_02900 3.32e-148 ycaC - - Q - - - Isochorismatase family
NBPHLDOP_02901 0.0 - - - EGP - - - Major Facilitator Superfamily
NBPHLDOP_02902 1.38e-274 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
NBPHLDOP_02903 2.11e-220 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
NBPHLDOP_02904 1.08e-84 manO - - S - - - Domain of unknown function (DUF956)
NBPHLDOP_02905 1.73e-216 manN - - G ko:K02796,ko:K02815 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
NBPHLDOP_02906 1.57e-171 manM - - G ko:K02746,ko:K02795,ko:K02814 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
NBPHLDOP_02907 1.44e-230 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NBPHLDOP_02908 9.77e-279 - - - EGP - - - Major facilitator Superfamily
NBPHLDOP_02909 1.31e-245 - - - K ko:K20373 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix XRE-family like proteins
NBPHLDOP_02910 8.33e-193 - - - K - - - Helix-turn-helix XRE-family like proteins
NBPHLDOP_02911 6.17e-204 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix XRE-family like proteins
NBPHLDOP_02913 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NBPHLDOP_02914 6.58e-173 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NBPHLDOP_02915 4.51e-41 - - - - - - - -
NBPHLDOP_02916 2.97e-305 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NBPHLDOP_02917 1.33e-166 - - - S - - - Protein of unknown function (DUF975)
NBPHLDOP_02918 2.15e-21 - - - S - - - Iron-sulphur cluster biosynthesis
NBPHLDOP_02919 1.4e-69 - - - - - - - -
NBPHLDOP_02920 6.11e-106 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
NBPHLDOP_02921 0.0 ydbT - - S ko:K08981 - ko00000 Bacterial PH domain
NBPHLDOP_02922 7.76e-186 - - - S - - - AAA ATPase domain
NBPHLDOP_02923 5.81e-217 - - - G - - - Phosphotransferase enzyme family
NBPHLDOP_02924 1.09e-170 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NBPHLDOP_02925 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NBPHLDOP_02926 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NBPHLDOP_02927 9.37e-129 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NBPHLDOP_02928 7.75e-138 - - - S ko:K06384 - ko00000 Stage II sporulation protein M
NBPHLDOP_02929 1.51e-90 moxR - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
NBPHLDOP_02930 6.74e-112 moxR - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
NBPHLDOP_02931 5.5e-238 - - - S - - - Protein of unknown function DUF58
NBPHLDOP_02932 1.77e-51 yebA - - E - - - Transglutaminase/protease-like homologues
NBPHLDOP_02933 0.0 yebA - - E - - - Transglutaminase/protease-like homologues
NBPHLDOP_02934 2.11e-273 - - - M - - - Glycosyl transferases group 1
NBPHLDOP_02935 1.34e-126 thgA3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
NBPHLDOP_02936 9.44e-190 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
NBPHLDOP_02937 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
NBPHLDOP_02938 8.59e-149 - - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
NBPHLDOP_02939 2.11e-61 yjdF3 - - S - - - Protein of unknown function (DUF2992)
NBPHLDOP_02940 1.09e-273 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
NBPHLDOP_02941 5.39e-292 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 2-hydroxycarboxylate transporter family
NBPHLDOP_02942 0.0 dpiB 2.7.13.3 - T ko:K02476,ko:K11614 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Single cache domain 3
NBPHLDOP_02943 1.62e-159 malR - - KT ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 cheY-homologous receiver domain
NBPHLDOP_02944 6.61e-196 - - - I - - - NAD binding domain of 6-phosphogluconate dehydrogenase
NBPHLDOP_02945 5.33e-124 M1-431 - - S - - - Protein of unknown function (DUF1706)
NBPHLDOP_02946 1.58e-86 - - - - - - - -
NBPHLDOP_02947 2.35e-286 yagE - - E - - - Amino acid permease
NBPHLDOP_02948 7.05e-219 - - - O - - - protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NBPHLDOP_02949 3.09e-212 sip - - L - - - Belongs to the 'phage' integrase family
NBPHLDOP_02950 2.54e-55 - - - L - - - DNA integration
NBPHLDOP_02951 6.37e-144 - - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
NBPHLDOP_02953 7.41e-45 - - - - - - - -
NBPHLDOP_02954 5.45e-26 - - - - - - - -
NBPHLDOP_02955 3.31e-39 - - - - - - - -
NBPHLDOP_02957 7.72e-35 - - - - - - - -
NBPHLDOP_02958 1.64e-205 - - - L - - - Bifunctional DNA primase/polymerase, N-terminal
NBPHLDOP_02959 0.0 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4
NBPHLDOP_02960 9.69e-72 - - - S - - - Phage head-tail joining protein
NBPHLDOP_02962 1.06e-28 - - - L - - - HNH endonuclease
NBPHLDOP_02963 9.78e-107 terS - - L - - - Phage terminase, small subunit
NBPHLDOP_02964 0.0 terL - - S - - - overlaps another CDS with the same product name
NBPHLDOP_02965 3e-29 - - - - - - - -
NBPHLDOP_02966 5.1e-284 - - - S - - - Phage portal protein
NBPHLDOP_02967 0.0 - - - S ko:K06904 - ko00000 Phage capsid family
NBPHLDOP_02968 8.23e-62 - - - S - - - Phage gp6-like head-tail connector protein
NBPHLDOP_02969 2.3e-23 - - - - - - - -
NBPHLDOP_02970 1.4e-35 ytgB - - S - - - Transglycosylase associated protein
NBPHLDOP_02972 3.23e-218 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NBPHLDOP_02973 2.32e-233 - - - D ko:K06889 - ko00000 Alpha beta
NBPHLDOP_02974 5.29e-239 lipA - - I - - - Carboxylesterase family
NBPHLDOP_02975 1.68e-275 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
NBPHLDOP_02976 9.2e-101 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NBPHLDOP_02977 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
NBPHLDOP_02978 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NBPHLDOP_02979 2.05e-168 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NBPHLDOP_02980 3.86e-192 - - - S - - - haloacid dehalogenase-like hydrolase
NBPHLDOP_02981 8.43e-59 - - - - - - - -
NBPHLDOP_02982 6.72e-19 - - - - - - - -
NBPHLDOP_02983 3.71e-239 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NBPHLDOP_02984 7.13e-161 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NBPHLDOP_02985 2.53e-265 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
NBPHLDOP_02986 1.77e-220 - - - M - - - Leucine rich repeats (6 copies)
NBPHLDOP_02987 0.0 - - - M - - - Leucine rich repeats (6 copies)
NBPHLDOP_02988 3.28e-257 ypjH - - C ko:K08317 - ko00000,ko01000 dehydrogenase
NBPHLDOP_02989 5.35e-289 amd - - E - - - Peptidase family M20/M25/M40
NBPHLDOP_02990 1.48e-104 - - - S - - - Threonine/Serine exporter, ThrE
NBPHLDOP_02991 3.8e-175 labL - - S - - - Putative threonine/serine exporter
NBPHLDOP_02993 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NBPHLDOP_02994 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NBPHLDOP_02996 1.73e-171 jag - - S ko:K06346 - ko00000 R3H domain protein
NBPHLDOP_02997 4.53e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NBPHLDOP_02998 2.99e-77 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NBPHLDOP_02999 3.26e-23 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
NBPHLDOP_03000 5.71e-58 - - - L ko:K07483 - ko00000 Homeodomain-like domain
NBPHLDOP_03002 0.0 - - - M - - - Collagen binding domain
NBPHLDOP_03003 4.83e-50 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
NBPHLDOP_03004 8.52e-84 is18 - - L - - - Integrase core domain
NBPHLDOP_03005 2.62e-49 - - - L - - - Transposase DDE domain
NBPHLDOP_03007 1.14e-148 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
NBPHLDOP_03008 3.83e-61 - - - L - - - BRCA1 C Terminus (BRCT) domain
NBPHLDOP_03009 1.51e-77 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
NBPHLDOP_03010 3.15e-103 - - - L - - - Transposase DDE domain
NBPHLDOP_03011 3.82e-65 - - - M - - - Glycosyltransferase like family 2
NBPHLDOP_03012 2.08e-207 lacT - - K ko:K02531 - ko00000,ko03000 PRD domain
NBPHLDOP_03013 0.0 lacE 2.7.1.207 - G ko:K02787,ko:K02788 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system, EIIC
NBPHLDOP_03014 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NBPHLDOP_03015 2.65e-67 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
NBPHLDOP_03016 8.05e-106 - - - L - - - Transposase DDE domain
NBPHLDOP_03017 3.06e-77 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
NBPHLDOP_03018 2.99e-122 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
NBPHLDOP_03019 2.93e-279 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NBPHLDOP_03020 6.02e-217 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NBPHLDOP_03021 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
NBPHLDOP_03022 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
NBPHLDOP_03023 6.22e-102 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
NBPHLDOP_03024 2.15e-77 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
NBPHLDOP_03025 1.56e-103 - - - L - - - Transposase DDE domain
NBPHLDOP_03027 2.33e-200 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
NBPHLDOP_03028 2.14e-163 tnp1216 - - L ko:K07498 - ko00000 DDE domain
NBPHLDOP_03029 3.03e-192 larE - - S ko:K06864 - ko00000 NAD synthase
NBPHLDOP_03030 1.19e-170 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NBPHLDOP_03031 6.2e-175 larC 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
NBPHLDOP_03032 6.12e-157 larB - - S ko:K06898 - ko00000 AIR carboxylase
NBPHLDOP_03033 2.14e-163 tnp1216 - - L ko:K07498 - ko00000 DDE domain
NBPHLDOP_03034 2.15e-77 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
NBPHLDOP_03035 1.56e-103 - - - L - - - Transposase DDE domain
NBPHLDOP_03037 2.33e-200 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
NBPHLDOP_03038 2.14e-163 tnp1216 - - L ko:K07498 - ko00000 DDE domain
NBPHLDOP_03039 3.03e-192 larE - - S ko:K06864 - ko00000 NAD synthase
NBPHLDOP_03040 1.19e-170 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NBPHLDOP_03041 6.2e-175 larC 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
NBPHLDOP_03042 6.12e-157 larB - - S ko:K06898 - ko00000 AIR carboxylase
NBPHLDOP_03043 2.14e-163 tnp1216 - - L ko:K07498 - ko00000 DDE domain
NBPHLDOP_03048 1.44e-61 - - - M - - - Domain of unknown function (DUF5011)
NBPHLDOP_03049 6.87e-11 - - - S - - - Protein of unknown function (DUF3801)
NBPHLDOP_03050 1.3e-154 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
NBPHLDOP_03051 1.74e-21 - - - - - - - -
NBPHLDOP_03052 1.47e-33 - - - - - - - -
NBPHLDOP_03053 2.54e-21 - - - U - - - PrgI family protein
NBPHLDOP_03054 6.91e-314 - - - U - - - AAA-like domain
NBPHLDOP_03055 8.57e-43 p40 - - D ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain
NBPHLDOP_03059 1.21e-74 - - - L - - - IrrE N-terminal-like domain
NBPHLDOP_03062 1.03e-08 - - - S - - - Bacterial mobilisation protein (MobC)
NBPHLDOP_03063 4e-112 - - - U - - - Relaxase/Mobilisation nuclease domain
NBPHLDOP_03064 2.74e-81 - - - L - - - Protein of unknown function (DUF3991)
NBPHLDOP_03065 2.14e-163 tnp1216 - - L ko:K07498 - ko00000 DDE domain
NBPHLDOP_03074 2.09e-101 repA - - S - - - Replication initiator protein A
NBPHLDOP_03075 5.81e-130 - - - D - - - AAA domain
NBPHLDOP_03077 9.99e-25 - - - - - - - -
NBPHLDOP_03078 2.08e-214 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
NBPHLDOP_03080 2.63e-27 - - - - - - - -

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)