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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
APHAPHFK_00001	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
APHAPHFK_00002	6.18e-262	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
APHAPHFK_00003	1.21e-44	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
APHAPHFK_00004	8.07e-259	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
APHAPHFK_00005	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
APHAPHFK_00006	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
APHAPHFK_00007	6.04e-12	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
APHAPHFK_00011	5.66e-08	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
APHAPHFK_00012	8.99e-99	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
APHAPHFK_00013	2.26e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
APHAPHFK_00014	1.41e-130	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
APHAPHFK_00015	3.26e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
APHAPHFK_00016	5.33e-119	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
APHAPHFK_00017	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit I
APHAPHFK_00018	1.35e-238	-	-	-	C	-	-	-	Cytochrome bd terminal oxidase subunit II
APHAPHFK_00019	1.76e-39	-	-	-	-	-	-	-	-
APHAPHFK_00020	1.48e-246	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
APHAPHFK_00021	9.94e-143	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
APHAPHFK_00023	0.0	-	-	-	L	-	-	-	Transposase DDE domain
APHAPHFK_00024	1.88e-100	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
APHAPHFK_00025	0.0	-	-	-	L	-	-	-	Transposase DDE domain
APHAPHFK_00026	0.000402	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
APHAPHFK_00027	1.47e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
APHAPHFK_00028	2.48e-252	-	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
APHAPHFK_00029	3.65e-274	-	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
APHAPHFK_00030	1.6e-204	p40	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain
APHAPHFK_00031	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
APHAPHFK_00032	3.54e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APHAPHFK_00033	3.25e-125	-	-	-	K	-	-	-	transcriptional regulator
APHAPHFK_00034	8.78e-197	-	-	-	G	-	-	-	Sucrose-6F-phosphate phosphohydrolase
APHAPHFK_00035	1.7e-62	-	-	-	-	-	-	-	-
APHAPHFK_00036	1.58e-164	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
APHAPHFK_00037	8.48e-134	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
APHAPHFK_00038	9.22e-147	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
APHAPHFK_00039	1.54e-73	-	-	-	-	-	-	-	-
APHAPHFK_00040	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
APHAPHFK_00041	1.45e-143	-	-	-	S	-	-	-	Membrane
APHAPHFK_00042	5.63e-114	-	-	-	-	-	-	-	-
APHAPHFK_00043	4.41e-67	-	-	-	-	-	-	-	-
APHAPHFK_00045	2.7e-232	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
APHAPHFK_00046	5.05e-66	-	-	-	-	-	-	-	-
APHAPHFK_00047	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
APHAPHFK_00048	1.13e-158	azlC	-	-	E	-	-	-	branched-chain amino acid
APHAPHFK_00049	1.29e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
APHAPHFK_00050	0.0	-	3.2.1.31	-	G	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 2 family
APHAPHFK_00051	0.0	-	-	-	M	-	-	-	Glycosyl hydrolase family 59
APHAPHFK_00053	5.06e-152	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
APHAPHFK_00054	3.83e-230	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
APHAPHFK_00055	7.4e-215	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
APHAPHFK_00056	3.71e-137	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
APHAPHFK_00057	6.06e-278	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
APHAPHFK_00058	0.0	uxuB	1.1.1.57	-	G	ko:K00040	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Mannitol dehydrogenase C-terminal domain
APHAPHFK_00059	2.3e-293	-	-	-	G	-	-	-	Major Facilitator
APHAPHFK_00060	1.34e-163	kdgR	-	-	K	-	-	-	FCD domain
APHAPHFK_00061	1.44e-245	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
APHAPHFK_00062	0.0	-	-	-	M	-	-	-	Glycosyl hydrolase family 59
APHAPHFK_00063	3.4e-78	ps105	-	-	-	-	-	-	-
APHAPHFK_00064	1.31e-85	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
APHAPHFK_00065	1.98e-313	-	-	-	EGP	-	-	-	Major Facilitator
APHAPHFK_00066	6.91e-280	-	3.1.1.83	-	I	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	ko00000,ko00001,ko01000	Alpha beta hydrolase
APHAPHFK_00067	3.96e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
APHAPHFK_00069	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
APHAPHFK_00070	4.54e-138	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
APHAPHFK_00071	5.55e-157	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
APHAPHFK_00072	0.0	-	3.5.4.28, 3.5.4.31	-	F	ko:K12960	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
APHAPHFK_00073	4.53e-90	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
APHAPHFK_00074	5.87e-192	-	-	-	S	-	-	-	Protein of unknown function (DUF3100)
APHAPHFK_00076	1.37e-142	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
APHAPHFK_00077	3.39e-226	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
APHAPHFK_00078	2.13e-136	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
APHAPHFK_00079	7.45e-279	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
APHAPHFK_00080	5.26e-70	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
APHAPHFK_00081	3.6e-92	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
APHAPHFK_00083	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
APHAPHFK_00084	7.29e-46	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
APHAPHFK_00085	2.65e-133	dpsB	-	-	P	-	-	-	Belongs to the Dps family
APHAPHFK_00086	4.48e-152	flp	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
APHAPHFK_00087	5.03e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
APHAPHFK_00088	4.02e-116	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
APHAPHFK_00090	5.29e-206	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
APHAPHFK_00091	6.93e-261	-	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02770,ko:K02794,ko:K02795	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
APHAPHFK_00092	3.45e-64	-	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02770,ko:K02794,ko:K02795	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
APHAPHFK_00093	2.07e-106	frvA	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APHAPHFK_00094	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
APHAPHFK_00095	1.05e-181	-	-	-	K	-	-	-	SIS domain
APHAPHFK_00096	0.0	-	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
APHAPHFK_00097	3.33e-208	bglK_1	-	-	GK	-	-	-	ROK family
APHAPHFK_00099	3.66e-185	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
APHAPHFK_00100	1.67e-291	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
APHAPHFK_00101	2.53e-139	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
APHAPHFK_00102	1.37e-175	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
APHAPHFK_00103	4.15e-234	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
APHAPHFK_00104	0.0	-	-	-	EGP	-	-	-	Major Facilitator
APHAPHFK_00105	9.98e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
APHAPHFK_00106	1.67e-159	-	-	-	-	-	-	-	-
APHAPHFK_00108	1.93e-137	-	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	dTDP-4-dehydrorhamnose 3,5-epimerase
APHAPHFK_00109	3.28e-181	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
APHAPHFK_00110	8.2e-214	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
APHAPHFK_00111	2.73e-285	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
APHAPHFK_00112	1.79e-115	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
APHAPHFK_00113	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
APHAPHFK_00114	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
APHAPHFK_00115	3.6e-241	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
APHAPHFK_00116	3.52e-252	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
APHAPHFK_00117	8.46e-84	-	-	-	-	-	-	-	-
APHAPHFK_00118	8.49e-66	-	-	-	K	-	-	-	sequence-specific DNA binding
APHAPHFK_00119	1.64e-98	-	-	-	L	-	-	-	NUDIX domain
APHAPHFK_00120	1.38e-196	-	-	-	EG	-	-	-	EamA-like transporter family
APHAPHFK_00122	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
APHAPHFK_00123	4.7e-98	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
APHAPHFK_00124	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
APHAPHFK_00125	3.05e-282	-	-	-	-	-	-	-	-
APHAPHFK_00126	0.0	pts32BC	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
APHAPHFK_00127	1.3e-210	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
APHAPHFK_00128	4.64e-255	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
APHAPHFK_00129	4.34e-203	yleF	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
APHAPHFK_00130	1.71e-138	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
APHAPHFK_00131	1.9e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APHAPHFK_00132	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
APHAPHFK_00133	2.16e-266	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
APHAPHFK_00134	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
APHAPHFK_00135	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
APHAPHFK_00136	1.78e-73	cadC5	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
APHAPHFK_00137	7.78e-264	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
APHAPHFK_00138	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
APHAPHFK_00139	3.29e-169	-	-	-	-	-	-	-	-
APHAPHFK_00140	9.52e-37	-	-	-	-	-	-	-	-
APHAPHFK_00143	7.4e-196	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
APHAPHFK_00145	0.0	-	-	-	L	-	-	-	Uncharacterised protein family (UPF0236)
APHAPHFK_00146	3.94e-222	-	-	-	L	-	-	-	Transposase
APHAPHFK_00147	2.83e-238	yveB	-	-	I	-	-	-	PAP2 superfamily
APHAPHFK_00148	1.48e-272	mccF	-	-	V	-	-	-	LD-carboxypeptidase
APHAPHFK_00149	4.61e-57	-	-	-	-	-	-	-	-
APHAPHFK_00150	1.99e-262	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
APHAPHFK_00151	1.56e-55	-	-	-	-	-	-	-	-
APHAPHFK_00152	7.43e-144	-	-	-	-	-	-	-	-
APHAPHFK_00153	4.41e-293	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
APHAPHFK_00154	1.51e-77	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
APHAPHFK_00155	1.69e-107	-	-	-	L	-	-	-	Transposase DDE domain
APHAPHFK_00156	1.11e-111	-	-	-	-	-	-	-	-
APHAPHFK_00157	5.89e-257	yclK	-	-	T	-	-	-	Histidine kinase
APHAPHFK_00158	4.14e-155	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
APHAPHFK_00159	2.11e-118	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
APHAPHFK_00160	1.17e-245	ldhD3	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APHAPHFK_00161	2.99e-65	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
APHAPHFK_00162	4.89e-70	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
APHAPHFK_00163	1.66e-111	-	-	-	-	-	-	-	-
APHAPHFK_00164	0.0	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APHAPHFK_00165	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
APHAPHFK_00166	5.01e-171	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
APHAPHFK_00167	1.66e-57	-	-	-	-	-	-	-	-
APHAPHFK_00168	1e-76	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
APHAPHFK_00169	9.85e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
APHAPHFK_00170	0.0	XK27_07275	-	-	S	ko:K06901	-	ko00000,ko02000	permease
APHAPHFK_00171	1.06e-73	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
APHAPHFK_00174	4.16e-178	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
APHAPHFK_00175	1.06e-234	-	-	-	P	ko:K15551	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	NMT1-like family
APHAPHFK_00176	8.04e-184	-	-	-	P	ko:K02050,ko:K15552	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
APHAPHFK_00177	0.0	-	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
APHAPHFK_00178	0.0	-	-	-	S	ko:K07112	-	ko00000	Sulphur transport
APHAPHFK_00179	8.52e-211	-	-	-	K	-	-	-	LysR substrate binding domain
APHAPHFK_00180	3.61e-245	mhqA	-	-	E	ko:K15975	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APHAPHFK_00181	8.2e-58	-	-	-	-	-	-	-	-
APHAPHFK_00182	9.29e-138	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
APHAPHFK_00183	0.0	-	-	-	-	-	-	-	-
APHAPHFK_00185	6.03e-179	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
APHAPHFK_00186	2.83e-241	ynjC	-	-	S	-	-	-	Cell surface protein
APHAPHFK_00188	0.0	-	-	-	L	-	-	-	Mga helix-turn-helix domain
APHAPHFK_00189	1.81e-226	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
APHAPHFK_00190	7.16e-77	-	-	-	-	-	-	-	-
APHAPHFK_00191	0.0	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
APHAPHFK_00192	1.02e-280	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
APHAPHFK_00193	8.96e-172	-	-	-	K	-	-	-	DeoR C terminal sensor domain
APHAPHFK_00194	0.0	-	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
APHAPHFK_00195	9.14e-205	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
APHAPHFK_00196	2.21e-309	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
APHAPHFK_00197	1.16e-204	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
APHAPHFK_00198	7.19e-177	-	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
APHAPHFK_00199	0.0	bmr3	-	-	EGP	-	-	-	Major Facilitator
APHAPHFK_00200	3.05e-29	-	-	-	-	-	-	-	-
APHAPHFK_00202	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
APHAPHFK_00203	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
APHAPHFK_00204	2.26e-118	-	-	-	-	-	-	-	-
APHAPHFK_00205	1.41e-151	-	-	-	-	-	-	-	-
APHAPHFK_00206	2.88e-165	-	-	-	-	-	-	-	-
APHAPHFK_00207	6.87e-153	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
APHAPHFK_00208	8.68e-104	-	-	-	-	-	-	-	-
APHAPHFK_00209	1.1e-107	-	-	-	S	-	-	-	NUDIX domain
APHAPHFK_00210	7.96e-273	-	-	-	S	-	-	-	nuclear-transcribed mRNA catabolic process, no-go decay
APHAPHFK_00211	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
APHAPHFK_00212	2.16e-209	-	-	-	K	ko:K20373,ko:K20374,ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional activator, Rgg GadR MutR family
APHAPHFK_00213	0.0	fnq20	-	-	S	-	-	-	FAD-NAD(P)-binding
APHAPHFK_00214	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
APHAPHFK_00215	6.18e-150	-	-	-	-	-	-	-	-
APHAPHFK_00216	2.57e-308	-	-	-	S	ko:K06872	-	ko00000	TPM domain
APHAPHFK_00217	1.42e-183	yunE	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
APHAPHFK_00218	1.58e-74	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
APHAPHFK_00219	1.47e-07	-	-	-	-	-	-	-	-
APHAPHFK_00220	8.87e-85	-	-	-	-	-	-	-	-
APHAPHFK_00221	2.59e-69	-	-	-	-	-	-	-	-
APHAPHFK_00222	1.63e-109	-	-	-	C	-	-	-	Flavodoxin
APHAPHFK_00223	4.57e-49	-	-	-	-	-	-	-	-
APHAPHFK_00224	4.87e-37	-	-	-	-	-	-	-	-
APHAPHFK_00225	7.34e-222	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APHAPHFK_00226	1.87e-93	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
APHAPHFK_00227	1.55e-51	-	-	-	S	-	-	-	Transglycosylase associated protein
APHAPHFK_00228	2.04e-117	-	-	-	S	-	-	-	Protein conserved in bacteria
APHAPHFK_00229	9.32e-40	-	-	-	-	-	-	-	-
APHAPHFK_00230	1.62e-80	asp23	-	-	S	-	-	-	Asp23 family, cell envelope-related function
APHAPHFK_00231	3.02e-87	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
APHAPHFK_00232	2.34e-167	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
APHAPHFK_00233	4.96e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
APHAPHFK_00234	9.44e-159	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
APHAPHFK_00235	4.87e-50	-	-	-	L	-	-	-	Transposase
APHAPHFK_00236	6.51e-114	-	-	-	L	-	-	-	Transposase
APHAPHFK_00237	8.43e-155	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
APHAPHFK_00238	2.06e-137	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
APHAPHFK_00240	3.57e-165	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
APHAPHFK_00241	8.1e-87	-	-	-	-	-	-	-	-
APHAPHFK_00242	9.03e-173	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
APHAPHFK_00243	5.2e-188	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
APHAPHFK_00244	1.28e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
APHAPHFK_00245	1.11e-201	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
APHAPHFK_00246	8.4e-42	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
APHAPHFK_00247	5.66e-257	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
APHAPHFK_00248	2.39e-182	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
APHAPHFK_00249	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
APHAPHFK_00250	1.19e-161	-	-	-	-	-	-	-	-
APHAPHFK_00251	1.68e-156	vanR	-	-	K	-	-	-	response regulator
APHAPHFK_00252	1.45e-280	hpk31	-	-	T	-	-	-	Histidine kinase
APHAPHFK_00253	8.22e-305	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
APHAPHFK_00254	2.55e-111	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
APHAPHFK_00255	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
APHAPHFK_00256	3.16e-181	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
APHAPHFK_00257	9.98e-212	yvgN	-	-	C	-	-	-	Aldo keto reductase
APHAPHFK_00258	9.72e-183	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	DeoR C terminal sensor domain
APHAPHFK_00259	0.0	iolT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
APHAPHFK_00260	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
APHAPHFK_00261	1.78e-202	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
APHAPHFK_00262	2.79e-228	iolC	2.7.1.92	-	H	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
APHAPHFK_00263	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
APHAPHFK_00264	1.94e-246	iolG	1.1.1.18, 1.1.1.369	-	C	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
APHAPHFK_00265	1.01e-250	iolG2	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
APHAPHFK_00266	1.54e-224	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
APHAPHFK_00267	4.19e-206	iolJ	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
APHAPHFK_00268	1.75e-87	yodA	-	-	S	-	-	-	Tautomerase enzyme
APHAPHFK_00269	7.85e-209	-	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
APHAPHFK_00270	1.54e-217	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
APHAPHFK_00271	9.72e-191	gntR	-	-	K	-	-	-	rpiR family
APHAPHFK_00272	2.98e-217	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
APHAPHFK_00273	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
APHAPHFK_00274	7.99e-271	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
APHAPHFK_00275	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
APHAPHFK_00276	7.49e-196	-	-	-	S	-	-	-	Glycosyl transferase family 2
APHAPHFK_00277	4.14e-163	welB	-	-	S	-	-	-	Glycosyltransferase like family 2
APHAPHFK_00278	5.12e-243	-	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 2
APHAPHFK_00279	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
APHAPHFK_00280	3.37e-250	-	-	-	S	-	-	-	Protein conserved in bacteria
APHAPHFK_00281	3.2e-76	-	-	-	-	-	-	-	-
APHAPHFK_00282	8.68e-169	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
APHAPHFK_00283	2.96e-173	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
APHAPHFK_00284	1.13e-215	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
APHAPHFK_00285	1.04e-209	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
APHAPHFK_00286	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
APHAPHFK_00287	6.87e-256	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
APHAPHFK_00288	7.52e-315	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
APHAPHFK_00289	2e-101	-	-	-	T	-	-	-	Sh3 type 3 domain protein
APHAPHFK_00290	2.29e-175	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
APHAPHFK_00291	3.43e-190	-	-	-	M	-	-	-	Glycosyltransferase like family 2
APHAPHFK_00292	2.7e-173	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
APHAPHFK_00293	5.1e-71	-	-	-	-	-	-	-	-
APHAPHFK_00294	4.32e-138	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
APHAPHFK_00295	3.52e-225	-	3.2.2.24	-	O	ko:K05521	-	ko00000,ko01000	ADP-ribosylglycohydrolase
APHAPHFK_00296	0.0	-	-	-	S	-	-	-	ABC transporter
APHAPHFK_00297	2.23e-180	ksgA	2.1.1.182, 2.1.1.197, 2.5.1.134	-	J	ko:K02169,ko:K02528,ko:K17216,ko:K17462	ko00270,ko00780,ko01100,ko01230,map00270,map00780,map01100,map01230	ko00000,ko00001,ko00002,ko01000,ko03009	rRNA (adenine-N6,N6-)-dimethyltransferase activity
APHAPHFK_00298	1.45e-46	-	-	-	-	-	-	-	-
APHAPHFK_00299	1.13e-93	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
APHAPHFK_00301	1.46e-57	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
APHAPHFK_00302	8.41e-172	-	-	-	S	-	-	-	Putative threonine/serine exporter
APHAPHFK_00303	5.92e-97	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
APHAPHFK_00304	5.62e-274	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
APHAPHFK_00305	5.16e-192	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
APHAPHFK_00306	8.13e-185	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
APHAPHFK_00307	1.74e-179	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
APHAPHFK_00308	4.25e-160	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
APHAPHFK_00309	5.08e-72	-	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
APHAPHFK_00310	5.34e-214	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
APHAPHFK_00311	1.66e-305	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APHAPHFK_00312	1.99e-148	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
APHAPHFK_00313	6.82e-295	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
APHAPHFK_00314	5.43e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
APHAPHFK_00315	1.09e-217	p75	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
APHAPHFK_00316	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
APHAPHFK_00317	1.16e-208	-	-	-	-	-	-	-	-
APHAPHFK_00318	1.38e-154	-	-	-	-	-	-	-	-
APHAPHFK_00319	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
APHAPHFK_00320	3.35e-305	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
APHAPHFK_00321	1.1e-114	-	-	-	-	-	-	-	-
APHAPHFK_00322	1.66e-249	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
APHAPHFK_00323	1.33e-167	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
APHAPHFK_00324	2.82e-281	agaS	-	-	G	ko:K02082	-	ko00000,ko01000	SIS domain
APHAPHFK_00325	1.12e-288	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
APHAPHFK_00326	0.0	bgaC	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
APHAPHFK_00327	3.25e-107	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
APHAPHFK_00328	3.11e-166	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
APHAPHFK_00329	2.21e-188	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
APHAPHFK_00330	1.91e-85	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
APHAPHFK_00331	4.29e-226	lacC	2.7.1.144	-	F	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
APHAPHFK_00332	1.69e-189	srlD	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	KR domain
APHAPHFK_00333	1.74e-308	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
APHAPHFK_00334	0.0	-	-	-	L	-	-	-	Transposase DDE domain
APHAPHFK_00335	1.7e-112	-	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APHAPHFK_00336	8.14e-63	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
APHAPHFK_00337	1.12e-208	-	-	-	-	-	-	-	-
APHAPHFK_00338	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
APHAPHFK_00339	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
APHAPHFK_00340	2.3e-293	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
APHAPHFK_00341	5.02e-298	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
APHAPHFK_00342	3.42e-258	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
APHAPHFK_00343	0.0	-	-	-	U	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APHAPHFK_00344	2.02e-78	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
APHAPHFK_00345	2.26e-65	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
APHAPHFK_00346	5.19e-251	-	-	-	E	-	-	-	M42 glutamyl aminopeptidase
APHAPHFK_00347	0.0	-	-	-	GKT	ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APHAPHFK_00348	4.93e-303	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
APHAPHFK_00349	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
APHAPHFK_00350	6.96e-158	-	-	-	S	ko:K03824	-	ko00000,ko01000	Acetyltransferase (GNAT) family
APHAPHFK_00352	0.0	nisT	-	-	V	ko:K06147,ko:K20485	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	ABC transporter
APHAPHFK_00353	1.12e-123	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
APHAPHFK_00354	2.41e-314	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
APHAPHFK_00355	5.88e-146	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
APHAPHFK_00356	5.67e-165	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
APHAPHFK_00357	2.96e-106	thiW	-	-	S	-	-	-	Thiamine-precursor transporter protein (ThiW)
APHAPHFK_00358	3.99e-194	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
APHAPHFK_00359	1.43e-134	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
APHAPHFK_00360	1.98e-196	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
APHAPHFK_00361	0.0	-	-	-	E	-	-	-	Amino acid permease
APHAPHFK_00362	5.98e-242	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
APHAPHFK_00363	1.39e-07	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
APHAPHFK_00364	2.08e-213	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APHAPHFK_00365	2.42e-60	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
APHAPHFK_00366	4.98e-49	-	-	-	-	-	-	-	-
APHAPHFK_00367	0.0	-	-	-	L	-	-	-	Transposase DDE domain
APHAPHFK_00373	5.72e-199	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
APHAPHFK_00374	1.67e-66	-	-	-	-	-	-	-	-
APHAPHFK_00375	0.0	pbpC	-	-	M	ko:K21467	-	ko00000,ko01011	NTF2-like N-terminal transpeptidase domain
APHAPHFK_00376	0.0	-	-	-	L	-	-	-	Transposase DDE domain
APHAPHFK_00378	1.06e-08	-	-	-	K	-	-	-	Helix-turn-helix domain
APHAPHFK_00379	3.38e-308	-	-	-	EGP	-	-	-	Major Facilitator
APHAPHFK_00380	1.27e-94	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
APHAPHFK_00381	6.08e-136	-	-	-	-	-	-	-	-
APHAPHFK_00382	8.52e-41	-	-	-	-	-	-	-	-
APHAPHFK_00383	1.71e-53	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
APHAPHFK_00384	1.11e-74	-	-	-	-	-	-	-	-
APHAPHFK_00385	3.86e-107	-	-	-	-	-	-	-	-
APHAPHFK_00386	0.0	-	-	-	K	ko:K02538	-	ko00000,ko03000	PRD domain
APHAPHFK_00387	2.48e-91	-	-	-	G	ko:K02806	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APHAPHFK_00388	8.5e-100	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APHAPHFK_00389	5.34e-64	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
APHAPHFK_00390	3.36e-202	-	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
APHAPHFK_00391	7.16e-155	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
APHAPHFK_00392	2.23e-166	alsE	-	-	G	ko:K17195	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Ribulose-phosphate 3 epimerase family
APHAPHFK_00393	8.85e-102	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APHAPHFK_00394	1.2e-59	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system galactitol-specific IIB component
APHAPHFK_00395	3.87e-88	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
APHAPHFK_00396	1.48e-246	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
APHAPHFK_00397	9.48e-241	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
APHAPHFK_00398	8.16e-206	tktN	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, thiamine diphosphate binding domain
APHAPHFK_00399	9.56e-243	tktC	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase
APHAPHFK_00400	8.9e-214	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
APHAPHFK_00401	5.18e-172	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
APHAPHFK_00402	6.85e-103	-	2.7.1.202	-	GT	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APHAPHFK_00403	2.31e-69	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
APHAPHFK_00404	7.64e-223	-	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
APHAPHFK_00405	1.48e-246	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
APHAPHFK_00406	1.86e-188	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
APHAPHFK_00407	2.66e-217	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
APHAPHFK_00408	4.83e-108	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
APHAPHFK_00409	2.58e-93	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
APHAPHFK_00410	0.0	-	-	-	G	-	-	-	PTS system sorbose-specific iic component
APHAPHFK_00411	1.74e-162	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
APHAPHFK_00412	3.05e-237	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
APHAPHFK_00413	1.37e-218	-	-	-	P	-	-	-	YhfZ C-terminal domain
APHAPHFK_00415	1.01e-75	-	-	-	S	-	-	-	Protein of unknown function DUF2620
APHAPHFK_00416	5.79e-275	-	-	-	S	-	-	-	Protein of unknown function
APHAPHFK_00417	7.89e-213	php	-	-	S	ko:K07048	-	ko00000	Phosphotriesterase family
APHAPHFK_00418	2.17e-264	-	-	-	E	-	-	-	Cys/Met metabolism PLP-dependent enzyme
APHAPHFK_00419	6.68e-283	-	-	-	E	-	-	-	Alanine racemase, N-terminal domain
APHAPHFK_00420	2.84e-305	-	-	-	G	-	-	-	Metalloenzyme superfamily
APHAPHFK_00421	4.54e-204	XK27_10120	-	-	K	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
APHAPHFK_00422	1.43e-125	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
APHAPHFK_00423	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding cassette cobalt transporter
APHAPHFK_00424	8.04e-192	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
APHAPHFK_00426	3.38e-274	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
APHAPHFK_00427	0.0	nagZ	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
APHAPHFK_00428	1.82e-227	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
APHAPHFK_00430	1.14e-148	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
APHAPHFK_00431	3.83e-61	-	-	-	L	-	-	-	BRCA1 C Terminus (BRCT) domain
APHAPHFK_00432	6.86e-114	-	-	-	-	-	-	-	-
APHAPHFK_00433	7.64e-88	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
APHAPHFK_00434	3.57e-260	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
APHAPHFK_00435	5.29e-238	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
APHAPHFK_00436	5.62e-166	-	-	-	M	-	-	-	domain protein
APHAPHFK_00437	0.0	yvcC	-	-	M	-	-	-	Cna protein B-type domain
APHAPHFK_00438	1.48e-246	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
APHAPHFK_00439	7.69e-134	-	-	-	-	-	-	-	-
APHAPHFK_00440	8.95e-140	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
APHAPHFK_00441	1.07e-61	holB	2.7.7.7	-	L	ko:K02341,ko:K02343,ko:K09384	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	replication factor c
APHAPHFK_00442	0.0	-	-	-	L	-	-	-	UvrD/REP helicase N-terminal domain
APHAPHFK_00443	0.0	-	-	-	L	ko:K07459	-	ko00000	AAA ATPase domain
APHAPHFK_00444	0.0	-	-	-	L	-	-	-	Transposase DDE domain
APHAPHFK_00445	1.75e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
APHAPHFK_00446	5.27e-191	is18	-	-	L	-	-	-	Integrase core domain
APHAPHFK_00447	1.16e-208	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
APHAPHFK_00448	1.77e-56	-	-	-	-	-	-	-	-
APHAPHFK_00449	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
APHAPHFK_00451	2.15e-77	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
APHAPHFK_00452	2.06e-108	-	-	-	L	-	-	-	Transposase DDE domain
APHAPHFK_00453	1.16e-248	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
APHAPHFK_00454	2.06e-108	-	-	-	L	-	-	-	Transposase DDE domain
APHAPHFK_00455	1.51e-77	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
APHAPHFK_00456	1.4e-162	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
APHAPHFK_00457	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
APHAPHFK_00458	2.8e-228	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
APHAPHFK_00459	2.97e-286	-	-	-	G	-	-	-	Major Facilitator Superfamily
APHAPHFK_00460	0.0	-	-	-	L	-	-	-	Transposase DDE domain
APHAPHFK_00461	1.4e-314	-	-	-	E	-	-	-	Peptidase family M20/M25/M40
APHAPHFK_00462	8.55e-99	-	-	-	K	-	-	-	DNA-binding transcription factor activity
APHAPHFK_00463	2.11e-54	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
APHAPHFK_00464	0.0	ebgA	3.2.1.23	-	G	ko:K01190,ko:K12111	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
APHAPHFK_00465	0.0	-	-	-	E	-	-	-	Amino Acid
APHAPHFK_00466	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
APHAPHFK_00467	3.34e-209	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
APHAPHFK_00468	0.0	-	-	-	GK	-	-	-	helix_turn_helix, arabinose operon control protein
APHAPHFK_00469	7.02e-269	-	-	-	G	-	-	-	Major Facilitator Superfamily
APHAPHFK_00470	0.0	-	-	-	S	ko:K12941	-	ko00000,ko01002	Peptidase dimerisation domain
APHAPHFK_00471	2.39e-255	-	1.5.1.28	-	C	ko:K04940	-	ko00000,ko01000	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
APHAPHFK_00472	5.87e-172	yxeO	-	-	E	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
APHAPHFK_00473	1.07e-209	-	-	-	ET	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
APHAPHFK_00474	5.19e-148	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
APHAPHFK_00475	9.72e-156	-	-	-	P	ko:K16958	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
APHAPHFK_00476	3.15e-174	-	-	-	-	-	-	-	-
APHAPHFK_00479	4.39e-25	-	-	-	S	-	-	-	YvrJ protein family
APHAPHFK_00480	1.02e-188	-	-	-	M	-	-	-	hydrolase, family 25
APHAPHFK_00481	1.17e-35	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
APHAPHFK_00482	6.48e-115	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
APHAPHFK_00483	3.29e-237	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
APHAPHFK_00484	2.12e-155	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APHAPHFK_00485	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
APHAPHFK_00486	1.58e-195	-	-	-	S	-	-	-	hydrolase
APHAPHFK_00487	8.23e-61	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
APHAPHFK_00488	9.06e-183	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
APHAPHFK_00496	0.0	-	-	-	L	-	-	-	Transposase DDE domain
APHAPHFK_00497	4.66e-196	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
APHAPHFK_00498	9.68e-252	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
APHAPHFK_00499	1.01e-224	-	-	-	-	-	-	-	-
APHAPHFK_00500	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
APHAPHFK_00501	1.61e-24	-	-	-	-	-	-	-	-
APHAPHFK_00502	1.18e-134	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
APHAPHFK_00503	1.22e-77	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
APHAPHFK_00504	1.72e-134	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
APHAPHFK_00505	1.47e-242	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
APHAPHFK_00506	2.13e-101	-	-	-	O	-	-	-	OsmC-like protein
APHAPHFK_00507	1.28e-155	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
APHAPHFK_00508	4.74e-267	-	-	-	-	-	-	-	-
APHAPHFK_00509	0.0	-	-	-	L	-	-	-	Transposase DDE domain
APHAPHFK_00512	1.96e-189	-	-	-	K	-	-	-	Helix-turn-helix domain
APHAPHFK_00513	0.0	-	-	-	L	-	-	-	Transposase DDE domain
APHAPHFK_00514	0.0	-	-	-	L	-	-	-	Exonuclease
APHAPHFK_00515	1.6e-58	-	-	-	L	-	-	-	RelB antitoxin
APHAPHFK_00516	1.04e-64	yczG	-	-	K	-	-	-	Helix-turn-helix domain
APHAPHFK_00517	4.89e-263	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
APHAPHFK_00518	2.37e-140	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
APHAPHFK_00519	3.42e-45	-	-	-	-	-	-	-	-
APHAPHFK_00520	7.61e-215	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
APHAPHFK_00521	0.0	cidC	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
APHAPHFK_00522	1.01e-61	-	-	-	-	-	-	-	-
APHAPHFK_00523	8.69e-92	pbpX	-	-	V	-	-	-	Beta-lactamase
APHAPHFK_00524	6.29e-135	pbpE	-	-	V	-	-	-	Beta-lactamase
APHAPHFK_00525	1e-248	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
APHAPHFK_00526	1.46e-183	-	-	-	H	-	-	-	Protein of unknown function (DUF1698)
APHAPHFK_00528	4.01e-184	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
APHAPHFK_00530	0.0	-	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamine synthetase N-terminal domain
APHAPHFK_00531	6.98e-289	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
APHAPHFK_00532	0.0	-	-	-	E	-	-	-	Amino acid permease
APHAPHFK_00534	7.73e-99	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
APHAPHFK_00535	2.26e-209	-	-	-	S	-	-	-	reductase
APHAPHFK_00536	3.95e-252	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
APHAPHFK_00537	9.54e-78	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
APHAPHFK_00538	3.91e-166	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
APHAPHFK_00539	7.2e-261	-	-	-	-	-	-	-	-
APHAPHFK_00540	1.49e-167	XK27_12140	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
APHAPHFK_00541	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APHAPHFK_00542	4.87e-164	-	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
APHAPHFK_00543	1.15e-259	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
APHAPHFK_00544	9.17e-210	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
APHAPHFK_00545	2.5e-259	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
APHAPHFK_00546	2.22e-138	-	-	-	-	-	-	-	-
APHAPHFK_00547	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
APHAPHFK_00548	0.0	ycaM	-	-	E	-	-	-	amino acid
APHAPHFK_00549	3.85e-314	xylP	-	-	G	-	-	-	MFS/sugar transport protein
APHAPHFK_00550	1.66e-121	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
APHAPHFK_00551	2.45e-213	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
APHAPHFK_00552	1.04e-214	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
APHAPHFK_00553	4.69e-199	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
APHAPHFK_00554	3.88e-206	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
APHAPHFK_00556	4.17e-280	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
APHAPHFK_00557	9.58e-214	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
APHAPHFK_00558	2.35e-209	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
APHAPHFK_00559	4.43e-222	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
APHAPHFK_00561	4.85e-184	-	-	-	-	-	-	-	-
APHAPHFK_00563	3.66e-274	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
APHAPHFK_00564	2.39e-186	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
APHAPHFK_00565	1.66e-156	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
APHAPHFK_00566	1.8e-181	-	-	-	-	-	-	-	-
APHAPHFK_00567	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
APHAPHFK_00568	7.7e-149	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
APHAPHFK_00569	1.82e-232	-	-	-	S	-	-	-	Cell surface protein
APHAPHFK_00570	8.36e-74	-	-	-	-	-	-	-	-
APHAPHFK_00571	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
APHAPHFK_00572	4.87e-50	-	-	-	L	-	-	-	Transposase
APHAPHFK_00573	6.51e-114	-	-	-	L	-	-	-	Transposase
APHAPHFK_00574	1.74e-163	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
APHAPHFK_00575	1.58e-83	-	-	-	-	-	-	-	-
APHAPHFK_00576	2.69e-158	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
APHAPHFK_00577	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
APHAPHFK_00578	1.87e-215	yicL	-	-	EG	-	-	-	EamA-like transporter family
APHAPHFK_00579	0.0	-	-	-	L	-	-	-	Uncharacterised protein family (UPF0236)
APHAPHFK_00580	0.0	-	-	-	-	-	-	-	-
APHAPHFK_00581	6.61e-186	CcmA5	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
APHAPHFK_00582	4.22e-92	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
APHAPHFK_00583	0.0	-	-	-	L	-	-	-	Transposase DDE domain
APHAPHFK_00584	5.24e-192	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
APHAPHFK_00585	3.21e-210	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
APHAPHFK_00586	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
APHAPHFK_00588	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
APHAPHFK_00589	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
APHAPHFK_00590	8.8e-283	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
APHAPHFK_00591	1.56e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
APHAPHFK_00592	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
APHAPHFK_00593	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
APHAPHFK_00594	1.6e-275	sstT	-	-	U	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
APHAPHFK_00595	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
APHAPHFK_00597	1.61e-221	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
APHAPHFK_00598	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
APHAPHFK_00599	3.08e-43	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
APHAPHFK_00600	1.55e-94	-	-	-	-	-	-	-	-
APHAPHFK_00601	1.95e-99	-	-	-	O	-	-	-	OsmC-like protein
APHAPHFK_00602	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
APHAPHFK_00603	2.84e-149	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
APHAPHFK_00604	1.41e-204	-	-	-	S	-	-	-	Aldo/keto reductase family
APHAPHFK_00605	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
APHAPHFK_00606	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF3800)
APHAPHFK_00607	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
APHAPHFK_00608	4.03e-80	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
APHAPHFK_00609	1.2e-95	-	-	-	K	-	-	-	LytTr DNA-binding domain
APHAPHFK_00610	1.14e-193	-	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
APHAPHFK_00611	4.35e-207	-	-	-	V	ko:K01990,ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
APHAPHFK_00612	8.08e-189	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
APHAPHFK_00613	6.19e-152	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
APHAPHFK_00614	1.06e-69	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
APHAPHFK_00615	7.57e-124	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NUDIX domain
APHAPHFK_00616	1.27e-154	-	-	-	K	-	-	-	response regulator
APHAPHFK_00617	1.59e-212	ycbM	-	-	T	-	-	-	Histidine kinase
APHAPHFK_00618	2.75e-214	-	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
APHAPHFK_00619	5.78e-148	-	-	-	S	-	-	-	ABC-2 family transporter protein
APHAPHFK_00620	8.8e-210	-	-	-	C	-	-	-	nadph quinone reductase
APHAPHFK_00621	5.66e-313	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
APHAPHFK_00622	1.97e-227	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
APHAPHFK_00623	2.7e-154	yqgG	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
APHAPHFK_00624	1.51e-195	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
APHAPHFK_00626	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
APHAPHFK_00627	2.39e-185	-	-	-	L	-	-	-	ATPase domain of DNA mismatch repair MUTS family
APHAPHFK_00628	4.42e-202	-	-	-	L	-	-	-	ATPase domain of DNA mismatch repair MUTS family
APHAPHFK_00629	2.67e-147	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
APHAPHFK_00630	2.82e-172	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
APHAPHFK_00631	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
APHAPHFK_00632	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
APHAPHFK_00633	4.68e-179	epsG	-	-	M	-	-	-	Glycosyltransferase like family 2
APHAPHFK_00635	2.12e-09	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	PRD domain
APHAPHFK_00636	3.54e-180	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	PRD domain
APHAPHFK_00637	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
APHAPHFK_00638	8.11e-174	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
APHAPHFK_00639	2.93e-174	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
APHAPHFK_00640	8.62e-66	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
APHAPHFK_00641	1.71e-284	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
APHAPHFK_00642	2.55e-248	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
APHAPHFK_00643	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
APHAPHFK_00644	5.88e-213	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
APHAPHFK_00645	2.37e-251	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
APHAPHFK_00646	8.23e-290	gatC	-	-	G	ko:K20114	ko02060,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
APHAPHFK_00648	2.82e-40	-	-	-	-	-	-	-	-
APHAPHFK_00649	2.09e-243	-	-	-	V	-	-	-	Beta-lactamase
APHAPHFK_00650	9.82e-164	-	-	-	S	-	-	-	Domain of unknown function (DUF4867)
APHAPHFK_00651	2.12e-226	lacC	2.7.1.144	-	H	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
APHAPHFK_00652	8.82e-241	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
APHAPHFK_00653	1.85e-121	lacB	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
APHAPHFK_00654	6.59e-96	lacA	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
APHAPHFK_00655	2.49e-182	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
APHAPHFK_00656	7.84e-152	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
APHAPHFK_00657	8.58e-271	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
APHAPHFK_00658	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
APHAPHFK_00659	2.78e-20	-	-	-	-	-	-	-	-
APHAPHFK_00660	5.22e-112	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
APHAPHFK_00661	6.38e-271	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
APHAPHFK_00662	4.7e-194	-	-	-	I	-	-	-	alpha/beta hydrolase fold
APHAPHFK_00663	3.65e-157	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
APHAPHFK_00665	1.34e-115	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
APHAPHFK_00666	3.31e-197	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
APHAPHFK_00667	3.97e-254	-	-	-	-	-	-	-	-
APHAPHFK_00669	1.34e-152	-	-	-	S	ko:K07118	-	ko00000	NmrA-like family
APHAPHFK_00670	0.0	bglB	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
APHAPHFK_00672	7.85e-216	XK27_00670	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
APHAPHFK_00674	2.52e-216	XK27_00670	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter
APHAPHFK_00675	1.68e-208	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
APHAPHFK_00676	4.1e-181	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APHAPHFK_00677	3.51e-224	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
APHAPHFK_00678	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
APHAPHFK_00679	8.07e-233	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferase family 2
APHAPHFK_00680	0.0	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
APHAPHFK_00681	2.64e-94	-	-	-	S	-	-	-	GtrA-like protein
APHAPHFK_00682	2.19e-15	-	-	-	-	-	-	-	-
APHAPHFK_00683	4.31e-165	ciaR	-	-	K	ko:K14983	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
APHAPHFK_00684	3.94e-309	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
APHAPHFK_00685	8.06e-87	-	-	-	S	-	-	-	Belongs to the HesB IscA family
APHAPHFK_00686	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
APHAPHFK_00687	5.32e-207	-	-	-	S	-	-	-	KR domain
APHAPHFK_00688	6.7e-203	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
APHAPHFK_00689	1.77e-158	ydgI	-	-	C	-	-	-	Nitroreductase family
APHAPHFK_00690	3.88e-264	lldD	1.13.12.4	-	C	ko:K00467	ko00620,map00620	ko00000,ko00001,ko01000	IMP dehydrogenase / GMP reductase domain
APHAPHFK_00693	3.31e-237	-	-	-	K	-	-	-	sequence-specific DNA binding
APHAPHFK_00694	5.58e-76	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
APHAPHFK_00695	2.05e-66	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
APHAPHFK_00696	1.46e-65	-	-	-	-	-	-	-	-
APHAPHFK_00697	2.09e-243	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
APHAPHFK_00698	5.83e-75	-	-	-	-	-	-	-	-
APHAPHFK_00699	6.82e-104	-	-	-	-	-	-	-	-
APHAPHFK_00700	5.52e-265	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
APHAPHFK_00701	1.99e-36	-	-	-	-	-	-	-	-
APHAPHFK_00702	2.46e-130	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
APHAPHFK_00703	5.63e-102	-	-	-	-	-	-	-	-
APHAPHFK_00704	3.6e-215	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
APHAPHFK_00705	2.82e-139	-	-	-	S	-	-	-	Flavin reductase like domain
APHAPHFK_00706	1.77e-185	-	-	-	-	-	-	-	-
APHAPHFK_00707	1e-136	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
APHAPHFK_00708	5.06e-83	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
APHAPHFK_00709	1.05e-221	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
APHAPHFK_00710	5.11e-208	mleR	-	-	K	-	-	-	LysR family
APHAPHFK_00711	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
APHAPHFK_00712	8.81e-218	mleP	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
APHAPHFK_00713	5.79e-117	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
APHAPHFK_00714	7.23e-124	-	-	-	-	-	-	-	-
APHAPHFK_00715	1.38e-228	-	-	-	K	-	-	-	sequence-specific DNA binding
APHAPHFK_00716	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
APHAPHFK_00717	0.0	pepF	-	-	E	-	-	-	Oligopeptidase F
APHAPHFK_00718	2.01e-102	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
APHAPHFK_00719	2.32e-79	-	-	-	-	-	-	-	-
APHAPHFK_00720	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
APHAPHFK_00721	2.31e-232	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
APHAPHFK_00722	1.03e-77	-	-	-	-	-	-	-	-
APHAPHFK_00723	1.09e-120	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
APHAPHFK_00724	2.39e-257	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
APHAPHFK_00725	6.4e-156	XK27_05175	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
APHAPHFK_00726	6.42e-101	-	-	-	K	-	-	-	Transcriptional regulator
APHAPHFK_00727	6.89e-231	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
APHAPHFK_00728	2.14e-110	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
APHAPHFK_00729	3.19e-202	dkgB	-	-	S	-	-	-	reductase
APHAPHFK_00730	1.84e-161	-	-	-	-	-	-	-	-
APHAPHFK_00731	2.64e-209	-	-	-	S	-	-	-	Alpha beta hydrolase
APHAPHFK_00732	1.57e-150	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
APHAPHFK_00733	5.25e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
APHAPHFK_00734	5.92e-284	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
APHAPHFK_00735	1.19e-112	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
APHAPHFK_00736	8.81e-135	yjbF	-	-	S	-	-	-	SNARE associated Golgi protein
APHAPHFK_00737	2.42e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
APHAPHFK_00738	4.98e-250	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
APHAPHFK_00739	2.16e-264	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
APHAPHFK_00740	1.71e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
APHAPHFK_00741	4.29e-87	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
APHAPHFK_00742	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
APHAPHFK_00743	1.45e-150	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
APHAPHFK_00744	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
APHAPHFK_00745	7.56e-266	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
APHAPHFK_00746	1.54e-305	ytoI	-	-	K	-	-	-	DRTGG domain
APHAPHFK_00747	6.11e-229	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
APHAPHFK_00748	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
APHAPHFK_00749	2.11e-221	-	-	-	-	-	-	-	-
APHAPHFK_00750	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
APHAPHFK_00751	9.98e-267	-	-	-	-	-	-	-	-
APHAPHFK_00752	4.89e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
APHAPHFK_00753	1.32e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
APHAPHFK_00754	1.85e-69	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
APHAPHFK_00755	3.45e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
APHAPHFK_00756	7.74e-121	cvpA	-	-	S	-	-	-	Colicin V production protein
APHAPHFK_00757	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
APHAPHFK_00758	3.64e-70	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
APHAPHFK_00759	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APHAPHFK_00760	1.46e-305	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
APHAPHFK_00761	1.2e-49	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APHAPHFK_00762	1.28e-315	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
APHAPHFK_00763	1.18e-109	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
APHAPHFK_00764	0.0	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
APHAPHFK_00765	9.48e-125	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
APHAPHFK_00766	2.59e-172	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Major intrinsic protein
APHAPHFK_00767	4.62e-112	ykuL	-	-	S	-	-	-	CBS domain
APHAPHFK_00768	1.76e-203	-	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
APHAPHFK_00769	5.26e-202	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
APHAPHFK_00771	7.19e-40	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
APHAPHFK_00772	4.56e-110	ytxH	-	-	S	-	-	-	YtxH-like protein
APHAPHFK_00773	4.48e-120	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
APHAPHFK_00774	5.39e-275	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
APHAPHFK_00775	6.12e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
APHAPHFK_00776	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin binding protein transpeptidase domain
APHAPHFK_00777	1.51e-163	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
APHAPHFK_00778	2.05e-174	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
APHAPHFK_00779	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
APHAPHFK_00780	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
APHAPHFK_00781	3.48e-73	-	-	-	-	-	-	-	-
APHAPHFK_00782	6.93e-240	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
APHAPHFK_00783	2.41e-153	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
APHAPHFK_00784	1.94e-148	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
APHAPHFK_00785	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
APHAPHFK_00786	5.33e-147	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
APHAPHFK_00787	4.68e-187	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
APHAPHFK_00788	6.18e-150	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
APHAPHFK_00789	4.31e-149	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
APHAPHFK_00790	6.48e-115	pgpA	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phosphatidylglycerophosphatase A
APHAPHFK_00791	6.69e-238	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
APHAPHFK_00792	3.11e-142	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
APHAPHFK_00793	2.02e-83	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
APHAPHFK_00794	1.45e-46	-	-	-	-	-	-	-	-
APHAPHFK_00795	1.13e-93	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
APHAPHFK_00822	2.21e-121	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
APHAPHFK_00823	0.0	ybeC	-	-	E	-	-	-	amino acid
APHAPHFK_00824	1.55e-294	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
APHAPHFK_00825	7.66e-251	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
APHAPHFK_00826	1.12e-224	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
APHAPHFK_00827	9.1e-281	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
APHAPHFK_00828	1.4e-58	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
APHAPHFK_00829	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
APHAPHFK_00830	1.8e-104	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
APHAPHFK_00831	1.45e-46	-	-	-	-	-	-	-	-
APHAPHFK_00832	1.13e-93	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
APHAPHFK_00837	1.48e-140	-	-	-	-	-	-	-	-
APHAPHFK_00838	1.66e-269	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
APHAPHFK_00839	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
APHAPHFK_00840	3.41e-107	-	-	-	K	-	-	-	MerR HTH family regulatory protein
APHAPHFK_00841	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
APHAPHFK_00842	1.3e-155	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
APHAPHFK_00843	3.69e-159	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
APHAPHFK_00844	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
APHAPHFK_00845	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
APHAPHFK_00846	1.97e-168	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
APHAPHFK_00847	8.09e-48	yhcC	-	-	S	ko:K07069	-	ko00000	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
APHAPHFK_00848	9.98e-182	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
APHAPHFK_00849	1.18e-122	-	-	-	F	-	-	-	NUDIX domain
APHAPHFK_00851	3.41e-112	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
APHAPHFK_00852	1.56e-289	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
APHAPHFK_00853	7.52e-239	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
APHAPHFK_00854	1.66e-84	-	-	-	S	-	-	-	acid phosphatase activity
APHAPHFK_00855	2.93e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
APHAPHFK_00856	4.86e-314	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
APHAPHFK_00857	3.78e-276	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
APHAPHFK_00858	8.12e-151	yjbH	-	-	Q	-	-	-	Thioredoxin
APHAPHFK_00859	3.46e-136	-	-	-	S	-	-	-	CYTH
APHAPHFK_00860	2.92e-160	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
APHAPHFK_00861	3.86e-194	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
APHAPHFK_00862	4.44e-222	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
APHAPHFK_00863	9.8e-259	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
APHAPHFK_00864	5.27e-147	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
APHAPHFK_00865	4.82e-187	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
APHAPHFK_00866	2.3e-254	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
APHAPHFK_00867	9.18e-83	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
APHAPHFK_00868	4.12e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
APHAPHFK_00869	1.72e-245	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
APHAPHFK_00870	9.63e-220	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
APHAPHFK_00871	4.88e-200	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
APHAPHFK_00872	6.48e-125	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
APHAPHFK_00873	8.84e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
APHAPHFK_00874	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
APHAPHFK_00875	4.47e-294	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
APHAPHFK_00876	7.12e-312	ymfH	-	-	S	-	-	-	Peptidase M16
APHAPHFK_00877	3.01e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
APHAPHFK_00878	1.8e-167	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
APHAPHFK_00879	7.57e-135	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
APHAPHFK_00880	1.18e-290	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
APHAPHFK_00881	1.41e-241	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
APHAPHFK_00882	2.63e-44	-	-	-	-	-	-	-	-
APHAPHFK_00883	0.0	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
APHAPHFK_00884	8.08e-154	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
APHAPHFK_00885	4.51e-299	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
APHAPHFK_00886	1.8e-117	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
APHAPHFK_00887	7.96e-127	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
APHAPHFK_00889	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
APHAPHFK_00890	1.11e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
APHAPHFK_00891	2.59e-160	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	ABC transporter
APHAPHFK_00892	4.17e-204	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
APHAPHFK_00893	2.13e-255	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
APHAPHFK_00894	9.79e-168	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
APHAPHFK_00895	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
APHAPHFK_00896	4.5e-200	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
APHAPHFK_00897	1.56e-205	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
APHAPHFK_00898	3.55e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
APHAPHFK_00899	6.38e-192	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
APHAPHFK_00900	1.75e-180	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
APHAPHFK_00901	1.33e-156	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
APHAPHFK_00902	2.79e-177	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
APHAPHFK_00903	5.65e-171	-	-	-	L	-	-	-	Helix-turn-helix domain
APHAPHFK_00904	0.0	yvlB	-	-	S	-	-	-	Putative adhesin
APHAPHFK_00905	7.01e-49	-	-	-	-	-	-	-	-
APHAPHFK_00906	2.28e-61	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
APHAPHFK_00907	5.82e-223	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
APHAPHFK_00908	1.2e-202	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
APHAPHFK_00909	5.39e-251	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
APHAPHFK_00910	8.36e-230	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
APHAPHFK_00911	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
APHAPHFK_00912	2.82e-153	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
APHAPHFK_00913	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
APHAPHFK_00914	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
APHAPHFK_00915	1.04e-110	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
APHAPHFK_00916	1.47e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
APHAPHFK_00917	3.49e-247	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
APHAPHFK_00918	1.66e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
APHAPHFK_00919	6.45e-105	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
APHAPHFK_00920	1.71e-131	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
APHAPHFK_00922	2.73e-241	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
APHAPHFK_00923	2.99e-247	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
APHAPHFK_00924	1.52e-282	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
APHAPHFK_00925	8.05e-180	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
APHAPHFK_00926	5.04e-314	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
APHAPHFK_00927	5.53e-84	-	-	-	-	-	-	-	-
APHAPHFK_00928	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
APHAPHFK_00929	1.48e-78	-	-	-	-	-	-	-	-
APHAPHFK_00930	2.92e-42	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
APHAPHFK_00931	2.23e-178	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
APHAPHFK_00932	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
APHAPHFK_00933	1.28e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
APHAPHFK_00934	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
APHAPHFK_00935	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
APHAPHFK_00936	1.05e-152	-	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
APHAPHFK_00937	7.78e-66	-	-	-	-	-	-	-	-
APHAPHFK_00938	9.23e-309	YSH1	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Metallo-beta-lactamase superfamily
APHAPHFK_00939	0.0	-	-	-	L	-	-	-	Uncharacterised protein family (UPF0236)
APHAPHFK_00940	9.05e-314	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
APHAPHFK_00941	1.1e-188	malF	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
APHAPHFK_00942	1.21e-213	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
APHAPHFK_00943	2.11e-249	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
APHAPHFK_00944	7.94e-134	-	-	-	K	ko:K06977	-	ko00000	Acetyltransferase (GNAT) domain
APHAPHFK_00945	5.33e-119	-	-	-	-	-	-	-	-
APHAPHFK_00946	5.93e-205	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
APHAPHFK_00947	4.68e-168	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
APHAPHFK_00948	4.47e-230	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
APHAPHFK_00949	5.07e-108	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
APHAPHFK_00950	6.5e-214	-	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APHAPHFK_00951	5.04e-279	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
APHAPHFK_00952	3.99e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
APHAPHFK_00953	2.84e-192	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
APHAPHFK_00954	0.0	-	-	-	L	-	-	-	Uncharacterised protein family (UPF0236)
APHAPHFK_00955	4.74e-212	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
APHAPHFK_00956	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
APHAPHFK_00957	4.84e-125	-	-	-	K	-	-	-	Cupin domain
APHAPHFK_00958	9.49e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
APHAPHFK_00959	2.13e-191	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
APHAPHFK_00960	7.08e-187	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
APHAPHFK_00961	2.08e-267	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
APHAPHFK_00962	1.2e-119	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
APHAPHFK_00963	2.37e-79	-	-	-	-	-	-	-	-
APHAPHFK_00965	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
APHAPHFK_00966	1.96e-154	-	-	-	K	-	-	-	Transcriptional regulator
APHAPHFK_00967	3.35e-250	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
APHAPHFK_00968	1.81e-168	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
APHAPHFK_00969	2.69e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
APHAPHFK_00970	1.04e-237	ybbR	-	-	S	-	-	-	YbbR-like protein
APHAPHFK_00971	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
APHAPHFK_00972	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
APHAPHFK_00973	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
APHAPHFK_00974	1.8e-119	-	-	-	S	-	-	-	VanZ like family
APHAPHFK_00975	1.75e-170	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
APHAPHFK_00976	1.71e-184	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
APHAPHFK_00977	1.26e-216	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
APHAPHFK_00978	4.92e-65	-	-	-	-	ko:K02245	-	ko00000,ko00002,ko02044	-
APHAPHFK_00980	7.97e-71	-	-	-	-	-	-	-	-
APHAPHFK_00981	2.14e-105	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
APHAPHFK_00982	1.84e-65	-	-	-	-	-	-	-	-
APHAPHFK_00983	4.7e-238	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
APHAPHFK_00984	1.35e-97	-	-	-	-	-	-	-	-
APHAPHFK_00985	1.83e-316	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
APHAPHFK_00986	1.07e-190	arbV	-	-	I	-	-	-	Phosphate acyltransferases
APHAPHFK_00987	2.87e-212	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
APHAPHFK_00988	1.98e-234	arbY	-	-	M	-	-	-	family 8
APHAPHFK_00989	6.04e-217	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
APHAPHFK_00990	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
APHAPHFK_00992	3.79e-92	-	-	-	S	-	-	-	SdpI/YhfL protein family
APHAPHFK_00993	2.22e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
APHAPHFK_00994	0.0	yclK	-	-	T	-	-	-	Histidine kinase
APHAPHFK_00995	1.15e-122	-	-	-	S	-	-	-	acetyltransferase
APHAPHFK_00996	2.21e-42	-	-	-	-	-	-	-	-
APHAPHFK_00997	1.49e-93	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
APHAPHFK_00998	2.24e-106	-	-	-	-	-	-	-	-
APHAPHFK_00999	1.41e-77	-	-	-	-	-	-	-	-
APHAPHFK_01000	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
APHAPHFK_01002	1.14e-260	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
APHAPHFK_01003	3.23e-175	-	3.1.1.5	-	E	ko:K10804	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	GDSL-like Lipase/Acylhydrolase
APHAPHFK_01004	1.92e-53	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
APHAPHFK_01005	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
APHAPHFK_01006	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
APHAPHFK_01007	2.76e-259	camS	-	-	S	-	-	-	sex pheromone
APHAPHFK_01008	1.26e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
APHAPHFK_01009	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
APHAPHFK_01010	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
APHAPHFK_01011	1.22e-248	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
APHAPHFK_01012	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
APHAPHFK_01013	2.92e-279	mod	2.1.1.72	-	L	ko:K00571,ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
APHAPHFK_01014	0.0	res	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
APHAPHFK_01015	0.0	-	-	-	L	-	-	-	Transposase DDE domain
APHAPHFK_01016	7.81e-282	yttB	-	-	EGP	-	-	-	Major Facilitator
APHAPHFK_01017	1.69e-191	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
APHAPHFK_01018	7.92e-216	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
APHAPHFK_01019	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
APHAPHFK_01020	3.32e-107	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
APHAPHFK_01021	5.78e-213	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
APHAPHFK_01022	4.79e-167	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
APHAPHFK_01023	1.82e-41	-	-	-	-	-	-	-	-
APHAPHFK_01024	3.07e-176	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
APHAPHFK_01025	3.83e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
APHAPHFK_01026	3.98e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
APHAPHFK_01027	2.8e-229	mocA	-	-	S	-	-	-	Oxidoreductase
APHAPHFK_01028	4.77e-306	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
APHAPHFK_01029	2.05e-63	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
APHAPHFK_01030	5.45e-94	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
APHAPHFK_01032	3.06e-07	-	-	-	-	-	-	-	-
APHAPHFK_01033	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
APHAPHFK_01034	6.99e-307	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
APHAPHFK_01035	3.46e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
APHAPHFK_01036	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
APHAPHFK_01037	3.14e-230	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
APHAPHFK_01038	3.71e-105	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
APHAPHFK_01039	2.34e-204	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
APHAPHFK_01040	2.38e-252	-	-	-	M	-	-	-	Glycosyltransferase like family 2
APHAPHFK_01042	2.12e-40	-	-	-	-	-	-	-	-
APHAPHFK_01043	6.6e-255	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
APHAPHFK_01044	1.37e-219	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
APHAPHFK_01045	2.37e-127	-	-	-	N	-	-	-	domain, Protein
APHAPHFK_01046	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
APHAPHFK_01047	0.0	bglH	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
APHAPHFK_01048	0.0	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
APHAPHFK_01049	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APHAPHFK_01050	3.64e-221	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
APHAPHFK_01051	5.01e-142	-	-	-	-	-	-	-	-
APHAPHFK_01052	2.43e-216	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
APHAPHFK_01053	6.22e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
APHAPHFK_01054	2.69e-27	-	-	-	T	-	-	-	PFAM SpoVT AbrB
APHAPHFK_01055	8.38e-107	yvbK	-	-	K	-	-	-	GNAT family
APHAPHFK_01056	7.8e-149	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
APHAPHFK_01057	6.51e-132	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
APHAPHFK_01058	1.87e-304	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
APHAPHFK_01059	4.2e-264	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
APHAPHFK_01060	1.93e-316	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
APHAPHFK_01062	1.8e-134	-	-	-	-	-	-	-	-
APHAPHFK_01063	5.8e-167	-	-	-	-	-	-	-	-
APHAPHFK_01064	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
APHAPHFK_01065	1.31e-142	vanZ	-	-	V	-	-	-	VanZ like family
APHAPHFK_01066	6.61e-196	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
APHAPHFK_01067	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
APHAPHFK_01068	6.26e-290	-	-	-	L	-	-	-	Pfam:Integrase_AP2
APHAPHFK_01070	1.18e-229	-	-	-	-	-	-	-	-
APHAPHFK_01071	1.58e-41	-	-	-	-	-	-	-	-
APHAPHFK_01072	5.03e-95	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
APHAPHFK_01076	1.59e-152	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3862)
APHAPHFK_01077	1.02e-100	-	-	-	E	-	-	-	Zn peptidase
APHAPHFK_01078	2.45e-72	-	-	-	K	-	-	-	Helix-turn-helix domain
APHAPHFK_01079	5.54e-50	-	-	-	K	-	-	-	Helix-turn-helix domain
APHAPHFK_01083	3.27e-129	-	-	-	-	-	-	-	-
APHAPHFK_01085	1.03e-22	-	-	-	-	-	-	-	-
APHAPHFK_01088	1.02e-202	-	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
APHAPHFK_01089	5.2e-172	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
APHAPHFK_01090	3.13e-206	-	-	-	L	-	-	-	Replication initiation and membrane attachment
APHAPHFK_01091	9.26e-103	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
APHAPHFK_01092	6.14e-09	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
APHAPHFK_01093	5.44e-05	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
APHAPHFK_01094	6.72e-97	-	-	-	-	-	-	-	-
APHAPHFK_01095	4.6e-53	-	-	-	-	-	-	-	-
APHAPHFK_01096	1.72e-75	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
APHAPHFK_01097	8.94e-49	-	-	-	-	-	-	-	-
APHAPHFK_01098	1.18e-38	-	-	-	-	-	-	-	-
APHAPHFK_01099	1.65e-122	-	-	-	S	-	-	-	Protein of unknown function (DUF1642)
APHAPHFK_01103	5.83e-84	-	-	-	-	-	-	-	-
APHAPHFK_01106	1.55e-101	-	-	-	-	-	-	-	-
APHAPHFK_01107	3.19e-286	-	-	-	S	-	-	-	GcrA cell cycle regulator
APHAPHFK_01108	5.9e-140	-	-	-	L	-	-	-	NUMOD4 motif
APHAPHFK_01109	2.95e-75	-	-	-	-	-	-	-	-
APHAPHFK_01110	3.96e-114	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
APHAPHFK_01111	0.0	-	-	-	S	ko:K06909	-	ko00000	Terminase RNAseH like domain
APHAPHFK_01112	0.0	-	-	-	S	-	-	-	Phage portal protein
APHAPHFK_01113	9.51e-239	-	-	-	S	-	-	-	head morphogenesis protein, SPP1 gp7 family
APHAPHFK_01114	3.77e-139	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
APHAPHFK_01115	3.31e-238	gpG	-	-	-	-	-	-	-
APHAPHFK_01116	2.25e-83	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
APHAPHFK_01117	1.98e-68	-	-	-	-	-	-	-	-
APHAPHFK_01118	2.12e-67	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
APHAPHFK_01119	6.75e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF3168)
APHAPHFK_01120	9.54e-140	-	-	-	S	-	-	-	Phage tail tube protein
APHAPHFK_01121	3.39e-67	-	-	-	S	-	-	-	Phage tail assembly chaperone protein, TAC
APHAPHFK_01122	2.71e-74	-	-	-	-	-	-	-	-
APHAPHFK_01123	0.0	-	-	-	S	-	-	-	phage tail tape measure protein
APHAPHFK_01124	0.0	-	-	-	S	-	-	-	Phage tail protein
APHAPHFK_01125	0.0	-	-	-	S	-	-	-	cellulase activity
APHAPHFK_01126	1.4e-69	-	-	-	-	-	-	-	-
APHAPHFK_01128	2.09e-63	-	-	-	-	-	-	-	-
APHAPHFK_01129	2.07e-83	hol	-	-	S	-	-	-	Bacteriophage holin
APHAPHFK_01130	9.54e-302	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
APHAPHFK_01131	3.01e-63	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
APHAPHFK_01132	4.38e-184	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
APHAPHFK_01133	1.88e-107	-	-	-	S	-	-	-	Pfam Transposase IS66
APHAPHFK_01134	2.76e-294	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferases group 1
APHAPHFK_01135	1.88e-221	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
APHAPHFK_01136	4e-110	guaD	-	-	FJ	-	-	-	MafB19-like deaminase
APHAPHFK_01140	2.13e-274	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
APHAPHFK_01142	1.56e-25	-	-	-	-	-	-	-	-
APHAPHFK_01143	1.53e-126	yttB	-	-	EGP	-	-	-	Major Facilitator
APHAPHFK_01144	3.71e-140	-	-	-	E	-	-	-	Major Facilitator Superfamily
APHAPHFK_01145	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
APHAPHFK_01148	6.59e-171	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
APHAPHFK_01149	1.29e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
APHAPHFK_01150	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
APHAPHFK_01151	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
APHAPHFK_01152	1.29e-181	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
APHAPHFK_01153	5.78e-212	catE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
APHAPHFK_01154	8.62e-253	ampC	-	-	V	-	-	-	Beta-lactamase
APHAPHFK_01155	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
APHAPHFK_01156	2.02e-144	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
APHAPHFK_01157	2.13e-10	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
APHAPHFK_01158	3.51e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
APHAPHFK_01159	1.85e-202	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
APHAPHFK_01160	7.33e-248	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
APHAPHFK_01161	1.29e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
APHAPHFK_01162	1.51e-145	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
APHAPHFK_01163	7.1e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
APHAPHFK_01164	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
APHAPHFK_01165	3.52e-87	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
APHAPHFK_01166	1.67e-117	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
APHAPHFK_01167	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
APHAPHFK_01168	1.78e-211	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
APHAPHFK_01169	3.68e-15	-	-	-	-	-	-	-	-
APHAPHFK_01170	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
APHAPHFK_01171	6.51e-83	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
APHAPHFK_01172	3.55e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
APHAPHFK_01173	2.13e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
APHAPHFK_01174	5.48e-35	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
APHAPHFK_01175	1.96e-73	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
APHAPHFK_01176	2.92e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
APHAPHFK_01177	1.92e-283	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
APHAPHFK_01178	1.2e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
APHAPHFK_01179	8.95e-273	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
APHAPHFK_01180	3.82e-190	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
APHAPHFK_01181	2.13e-192	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
APHAPHFK_01182	1.78e-238	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
APHAPHFK_01183	5.58e-151	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
APHAPHFK_01184	4.15e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
APHAPHFK_01185	3.62e-245	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
APHAPHFK_01186	3.32e-289	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
APHAPHFK_01187	1.42e-102	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
APHAPHFK_01188	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
APHAPHFK_01189	2.14e-36	-	-	-	-	-	-	-	-
APHAPHFK_01190	4.01e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
APHAPHFK_01191	1.5e-231	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
APHAPHFK_01192	2.16e-206	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
APHAPHFK_01193	6.47e-110	uspA	-	-	T	-	-	-	universal stress protein
APHAPHFK_01194	1.41e-53	-	-	-	-	-	-	-	-
APHAPHFK_01195	9.18e-305	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
APHAPHFK_01196	0.0	-	6.3.2.2	-	M	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain protein
APHAPHFK_01197	1.19e-97	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
APHAPHFK_01198	2.54e-145	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
APHAPHFK_01199	1.24e-159	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
APHAPHFK_01200	1.49e-194	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
APHAPHFK_01201	1.82e-161	-	-	-	G	-	-	-	Phosphoglycerate mutase family
APHAPHFK_01202	1.46e-200	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
APHAPHFK_01203	9.61e-218	-	-	-	IQ	-	-	-	NAD dependent epimerase/dehydratase family
APHAPHFK_01204	1.02e-178	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
APHAPHFK_01205	6.87e-172	-	-	-	F	-	-	-	deoxynucleoside kinase
APHAPHFK_01206	3.46e-204	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphatase and related hydrolases of the PHP family
APHAPHFK_01207	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
APHAPHFK_01208	1.2e-206	-	-	-	T	-	-	-	GHKL domain
APHAPHFK_01209	1.24e-156	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
APHAPHFK_01210	3.91e-216	bcrA	-	-	V	ko:K01990,ko:K19309	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
APHAPHFK_01211	1.12e-168	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
APHAPHFK_01212	1.26e-209	-	-	-	K	-	-	-	Transcriptional regulator
APHAPHFK_01213	1.98e-104	yphH	-	-	S	-	-	-	Cupin domain
APHAPHFK_01214	2.24e-72	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
APHAPHFK_01215	1.35e-142	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
APHAPHFK_01216	4.58e-213	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
APHAPHFK_01217	2.4e-112	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
APHAPHFK_01218	3.57e-200	degV	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
APHAPHFK_01219	4.08e-149	-	-	-	-	-	-	-	-
APHAPHFK_01220	1.77e-134	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
APHAPHFK_01221	2.25e-263	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
APHAPHFK_01222	1.94e-168	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
APHAPHFK_01223	1.15e-205	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
APHAPHFK_01224	0.0	-	-	-	-	-	-	-	-
APHAPHFK_01225	5.73e-240	-	-	-	-	-	-	-	-
APHAPHFK_01226	0.0	-	-	-	D	-	-	-	Putative exonuclease SbcCD, C subunit
APHAPHFK_01227	6.43e-146	-	-	-	D	-	-	-	Putative exonuclease SbcCD, C subunit
APHAPHFK_01228	1.77e-197	-	-	-	S	-	-	-	Protein of unknown function C-terminus (DUF2399)
APHAPHFK_01230	1.57e-233	-	-	-	-	-	-	-	-
APHAPHFK_01231	0.0	-	-	-	L	-	-	-	Transposase DDE domain
APHAPHFK_01232	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
APHAPHFK_01233	1.6e-107	-	-	-	-	-	-	-	-
APHAPHFK_01234	4.16e-181	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
APHAPHFK_01235	1.67e-291	-	-	-	E	-	-	-	Amino acid permease
APHAPHFK_01236	1.45e-120	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
APHAPHFK_01237	0.0	-	-	-	L	-	-	-	AAA domain
APHAPHFK_01238	5.31e-143	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
APHAPHFK_01239	4.28e-112	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
APHAPHFK_01240	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
APHAPHFK_01241	3.27e-276	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
APHAPHFK_01242	1.04e-289	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
APHAPHFK_01243	2.05e-151	-	-	-	K	ko:K01926	-	ko00000,ko03000	CoA binding domain
APHAPHFK_01245	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
APHAPHFK_01246	1.43e-310	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
APHAPHFK_01247	1.45e-150	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
APHAPHFK_01248	8.02e-152	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
APHAPHFK_01249	6.84e-229	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
APHAPHFK_01250	5.62e-193	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
APHAPHFK_01251	2.13e-113	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
APHAPHFK_01252	3.14e-147	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
APHAPHFK_01253	6.07e-182	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
APHAPHFK_01254	2.77e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
APHAPHFK_01255	1.34e-145	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
APHAPHFK_01256	1.99e-194	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
APHAPHFK_01257	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APHAPHFK_01258	4.32e-14	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
APHAPHFK_01259	1.49e-70	-	-	-	-	-	-	-	-
APHAPHFK_01260	1.61e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
APHAPHFK_01261	2.76e-218	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
APHAPHFK_01262	8.26e-80	ftsL	-	-	D	-	-	-	cell division protein FtsL
APHAPHFK_01263	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
APHAPHFK_01264	4.46e-228	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
APHAPHFK_01265	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
APHAPHFK_01266	1.34e-257	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
APHAPHFK_01267	4.67e-196	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
APHAPHFK_01268	5.19e-308	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
APHAPHFK_01269	1.09e-290	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
APHAPHFK_01270	5.1e-102	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
APHAPHFK_01271	8.33e-61	yggT	-	-	D	ko:K02221	-	ko00000,ko02044	integral membrane protein
APHAPHFK_01272	2.83e-187	ylmH	-	-	S	-	-	-	S4 domain protein
APHAPHFK_01273	6e-116	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA protein
APHAPHFK_01274	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
APHAPHFK_01275	2.98e-49	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
APHAPHFK_01276	6.09e-200	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
APHAPHFK_01277	0.0	ydiC1	-	-	EGP	-	-	-	Major Facilitator
APHAPHFK_01278	6e-268	yaaN	-	-	P	-	-	-	Toxic anion resistance protein (TelA)
APHAPHFK_01279	1.39e-151	-	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
APHAPHFK_01280	7.71e-128	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
APHAPHFK_01281	3.34e-47	-	-	-	-	-	-	-	-
APHAPHFK_01282	2.38e-160	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
APHAPHFK_01283	5.06e-281	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
APHAPHFK_01284	3.61e-77	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
APHAPHFK_01285	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
APHAPHFK_01286	7.18e-279	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
APHAPHFK_01288	9.46e-159	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
APHAPHFK_01289	1.82e-153	-	-	-	S	-	-	-	repeat protein
APHAPHFK_01290	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
APHAPHFK_01291	2.35e-311	-	-	-	S	-	-	-	Sterol carrier protein domain
APHAPHFK_01292	7.21e-236	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
APHAPHFK_01293	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
APHAPHFK_01294	4.07e-43	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
APHAPHFK_01296	1.78e-97	-	-	-	-	-	-	-	-
APHAPHFK_01297	1.96e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
APHAPHFK_01298	1.4e-174	-	-	-	S	-	-	-	E1-E2 ATPase
APHAPHFK_01299	1.65e-266	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
APHAPHFK_01300	4.67e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
APHAPHFK_01301	7.46e-283	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
APHAPHFK_01302	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
APHAPHFK_01303	7.16e-201	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
APHAPHFK_01304	8.74e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
APHAPHFK_01305	2.22e-188	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
APHAPHFK_01306	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
APHAPHFK_01307	1.31e-268	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
APHAPHFK_01308	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
APHAPHFK_01309	2.84e-75	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
APHAPHFK_01310	2.48e-130	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
APHAPHFK_01311	2.96e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
APHAPHFK_01312	2.13e-249	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
APHAPHFK_01313	4.3e-151	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
APHAPHFK_01314	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
APHAPHFK_01315	7.05e-248	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
APHAPHFK_01316	1.01e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
APHAPHFK_01317	2.48e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
APHAPHFK_01318	1.24e-163	-	-	-	-	-	-	-	-
APHAPHFK_01319	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
APHAPHFK_01320	8.8e-209	-	-	-	S	-	-	-	Tetratricopeptide repeat
APHAPHFK_01321	4.73e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
APHAPHFK_01322	1.27e-65	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
APHAPHFK_01323	1.55e-68	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
APHAPHFK_01324	1.64e-177	-	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
APHAPHFK_01325	1.12e-83	pcaC	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
APHAPHFK_01326	1.02e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
APHAPHFK_01327	0.0	yknV	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
APHAPHFK_01328	8.34e-271	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
APHAPHFK_01329	5.9e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
APHAPHFK_01330	5.12e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
APHAPHFK_01331	2.28e-63	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
APHAPHFK_01332	2.34e-28	-	-	-	-	-	-	-	-
APHAPHFK_01333	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
APHAPHFK_01334	1.33e-172	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
APHAPHFK_01335	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
APHAPHFK_01336	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
APHAPHFK_01337	2.27e-217	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
APHAPHFK_01338	5.84e-172	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
APHAPHFK_01339	3.04e-296	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
APHAPHFK_01340	0.0	oatA	-	-	I	-	-	-	Acyltransferase
APHAPHFK_01341	3.56e-233	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
APHAPHFK_01342	1.89e-183	yqjQ	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
APHAPHFK_01343	5.47e-63	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
APHAPHFK_01344	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
APHAPHFK_01345	1.35e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
APHAPHFK_01346	3.37e-123	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
APHAPHFK_01347	0.0	ycjM	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
APHAPHFK_01348	4.53e-189	-	-	-	-	-	-	-	-
APHAPHFK_01349	2.06e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
APHAPHFK_01350	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
APHAPHFK_01351	9e-227	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
APHAPHFK_01352	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
APHAPHFK_01353	6.13e-95	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
APHAPHFK_01354	1.08e-210	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
APHAPHFK_01355	2.09e-212	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
APHAPHFK_01356	2.81e-88	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APHAPHFK_01357	8.93e-163	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
APHAPHFK_01358	3.83e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
APHAPHFK_01359	3.03e-178	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
APHAPHFK_01360	4.54e-125	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
APHAPHFK_01361	4.03e-61	fer	-	-	C	ko:K05337	-	ko00000	4Fe-4S single cluster domain of Ferredoxin I
APHAPHFK_01362	5.09e-238	-	-	-	S	-	-	-	Helix-turn-helix domain
APHAPHFK_01363	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
APHAPHFK_01364	9.84e-91	-	-	-	M	-	-	-	Lysin motif
APHAPHFK_01365	1.89e-150	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
APHAPHFK_01366	6.19e-300	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
APHAPHFK_01367	3.67e-312	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
APHAPHFK_01368	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
APHAPHFK_01369	1.71e-303	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
APHAPHFK_01370	2.95e-207	ypjC	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
APHAPHFK_01371	2.74e-286	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
APHAPHFK_01372	2.08e-110	-	-	-	-	-	-	-	-
APHAPHFK_01373	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
APHAPHFK_01374	2.17e-246	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
APHAPHFK_01375	1.54e-120	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
APHAPHFK_01376	4.5e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
APHAPHFK_01377	1.18e-191	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
APHAPHFK_01378	3.87e-202	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
APHAPHFK_01379	4.32e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
APHAPHFK_01380	3.45e-126	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
APHAPHFK_01381	2.52e-55	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
APHAPHFK_01382	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
APHAPHFK_01383	2.3e-78	XK27_02555	-	-	-	-	-	-	-
APHAPHFK_01385	2.92e-170	-	-	-	S	-	-	-	Domain of unknown function (DUF4918)
APHAPHFK_01386	1.35e-204	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
APHAPHFK_01387	2.13e-180	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
APHAPHFK_01388	2.8e-190	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
APHAPHFK_01389	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
APHAPHFK_01390	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
APHAPHFK_01391	1.21e-216	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
APHAPHFK_01392	2.06e-119	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
APHAPHFK_01393	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
APHAPHFK_01394	2.78e-221	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
APHAPHFK_01395	5.07e-143	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
APHAPHFK_01396	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
APHAPHFK_01397	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
APHAPHFK_01398	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
APHAPHFK_01399	3.64e-217	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
APHAPHFK_01400	1.15e-235	-	-	-	K	-	-	-	LysR substrate binding domain
APHAPHFK_01401	3.94e-221	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
APHAPHFK_01402	7.32e-270	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
APHAPHFK_01403	0.0	XK27_05700	-	-	V	ko:K02004,ko:K19084	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	FtsX-like permease family
APHAPHFK_01404	5.4e-176	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
APHAPHFK_01405	1.43e-223	-	-	-	T	-	-	-	Histidine kinase-like ATPases
APHAPHFK_01406	2.14e-165	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
APHAPHFK_01407	4.2e-284	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
APHAPHFK_01408	5.19e-90	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
APHAPHFK_01409	3.63e-95	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
APHAPHFK_01410	4.33e-146	-	-	-	C	-	-	-	Nitroreductase family
APHAPHFK_01411	8.74e-193	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
APHAPHFK_01412	2.01e-266	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
APHAPHFK_01413	5.01e-69	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
APHAPHFK_01414	3.38e-76	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
APHAPHFK_01415	4.44e-173	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
APHAPHFK_01416	1.05e-174	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
APHAPHFK_01417	3.44e-146	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
APHAPHFK_01418	2.09e-136	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
APHAPHFK_01419	1.44e-293	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
APHAPHFK_01420	3.99e-141	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
APHAPHFK_01421	3.83e-278	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
APHAPHFK_01422	1.3e-265	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Cys/Met metabolism PLP-dependent enzyme
APHAPHFK_01423	3.8e-130	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
APHAPHFK_01424	3.08e-207	-	-	-	S	-	-	-	EDD domain protein, DegV family
APHAPHFK_01426	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
APHAPHFK_01427	1.43e-67	-	-	-	S	-	-	-	MazG-like family
APHAPHFK_01428	3.31e-246	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
APHAPHFK_01429	1.9e-145	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
APHAPHFK_01430	9.32e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
APHAPHFK_01431	1.02e-197	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
APHAPHFK_01432	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
APHAPHFK_01433	5.32e-267	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
APHAPHFK_01434	4.76e-307	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
APHAPHFK_01435	5.04e-230	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
APHAPHFK_01436	1.15e-299	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
APHAPHFK_01437	7.77e-118	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
APHAPHFK_01439	4.27e-223	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
APHAPHFK_01440	1.4e-106	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
APHAPHFK_01441	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
APHAPHFK_01442	3.47e-85	-	-	-	S	-	-	-	Family of unknown function (DUF5322)
APHAPHFK_01443	5.59e-90	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
APHAPHFK_01444	1.72e-142	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
APHAPHFK_01445	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APHAPHFK_01446	9.43e-73	-	-	-	-	-	-	-	-
APHAPHFK_01447	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
APHAPHFK_01448	1.76e-51	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
APHAPHFK_01449	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APHAPHFK_01450	1.46e-240	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APHAPHFK_01451	9.22e-213	lysR	-	-	K	-	-	-	Transcriptional regulator
APHAPHFK_01452	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
APHAPHFK_01453	1e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
APHAPHFK_01454	5.13e-46	-	-	-	-	-	-	-	-
APHAPHFK_01455	9.34e-225	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
APHAPHFK_01456	8.68e-278	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
APHAPHFK_01458	5.37e-88	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
APHAPHFK_01459	2.28e-138	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
APHAPHFK_01460	1.03e-156	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
APHAPHFK_01461	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
APHAPHFK_01462	1.34e-112	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
APHAPHFK_01463	2.81e-149	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
APHAPHFK_01464	5.96e-146	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
APHAPHFK_01465	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
APHAPHFK_01466	3.43e-281	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
APHAPHFK_01467	2.66e-112	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
APHAPHFK_01468	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
APHAPHFK_01469	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
APHAPHFK_01470	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
APHAPHFK_01471	7.57e-215	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
APHAPHFK_01472	1.62e-232	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
APHAPHFK_01473	1.81e-250	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
APHAPHFK_01474	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
APHAPHFK_01475	3.25e-224	-	-	-	-	-	-	-	-
APHAPHFK_01476	6.15e-182	-	-	-	-	-	-	-	-
APHAPHFK_01477	4.01e-80	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
APHAPHFK_01478	1.8e-36	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
APHAPHFK_01479	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	(ABC) transporter
APHAPHFK_01480	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
APHAPHFK_01481	1.63e-190	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
APHAPHFK_01482	1.1e-165	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
APHAPHFK_01483	1.21e-257	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
APHAPHFK_01484	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
APHAPHFK_01485	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
APHAPHFK_01486	1.96e-224	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
APHAPHFK_01487	8.18e-288	sip	-	-	L	-	-	-	Phage integrase family
APHAPHFK_01489	8.69e-92	-	-	-	-	-	-	-	-
APHAPHFK_01490	8.79e-285	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
APHAPHFK_01491	2.21e-63	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
APHAPHFK_01492	8.63e-42	-	-	-	-	-	-	-	-
APHAPHFK_01494	1.99e-69	-	-	-	-	-	-	-	-
APHAPHFK_01495	0.0	-	-	-	S	-	-	-	cellulase activity
APHAPHFK_01496	0.0	-	-	-	-	-	-	-	-
APHAPHFK_01497	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
APHAPHFK_01498	5.92e-50	-	-	-	-	-	-	-	-
APHAPHFK_01499	5.08e-74	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
APHAPHFK_01500	2.61e-147	-	-	-	S	-	-	-	Phage tail tube protein
APHAPHFK_01501	1.91e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
APHAPHFK_01502	1.45e-93	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
APHAPHFK_01503	7.27e-73	-	-	-	S	-	-	-	Phage head-tail joining protein
APHAPHFK_01504	9.87e-44	-	-	-	-	-	-	-	-
APHAPHFK_01505	0.0	-	-	-	S	ko:K06904	-	ko00000	Phage capsid family
APHAPHFK_01506	3.05e-260	-	-	-	S	-	-	-	Phage portal protein
APHAPHFK_01508	0.0	-	-	-	S	-	-	-	Phage Terminase
APHAPHFK_01509	2.32e-104	-	-	-	L	-	-	-	Phage terminase, small subunit
APHAPHFK_01510	3e-127	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
APHAPHFK_01512	3.02e-174	icaA	2.4.1.212	GT2	M	ko:K00752,ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyltransferases, probably involved in cell wall biogenesis
APHAPHFK_01513	0.0	-	-	-	L	-	-	-	Transposase DDE domain
APHAPHFK_01516	4.33e-105	-	-	-	V	-	-	-	HNH nucleases
APHAPHFK_01517	1.08e-88	-	-	-	L	-	-	-	Single-strand binding protein family
APHAPHFK_01518	6.53e-172	-	-	-	-	-	-	-	-
APHAPHFK_01519	7.26e-11	-	-	-	S	-	-	-	HNH endonuclease
APHAPHFK_01522	1.45e-124	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
APHAPHFK_01524	1.61e-163	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
APHAPHFK_01525	9.27e-73	-	-	-	-	-	-	-	-
APHAPHFK_01526	2.67e-192	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
APHAPHFK_01527	2.36e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
APHAPHFK_01528	8.35e-84	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
APHAPHFK_01529	4.25e-85	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
APHAPHFK_01530	2.52e-107	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
APHAPHFK_01531	1.14e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
APHAPHFK_01532	1.47e-90	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
APHAPHFK_01533	5.66e-29	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
APHAPHFK_01534	4.18e-199	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
APHAPHFK_01535	4.59e-217	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
APHAPHFK_01536	7.61e-217	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
APHAPHFK_01537	4.4e-106	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
APHAPHFK_01538	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
APHAPHFK_01539	4.43e-309	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
APHAPHFK_01540	0.0	-	-	-	-	-	-	-	-
APHAPHFK_01541	2.51e-203	-	-	-	V	-	-	-	ABC transporter
APHAPHFK_01542	2.26e-108	-	-	-	FG	-	-	-	adenosine 5'-monophosphoramidase activity
APHAPHFK_01543	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
APHAPHFK_01544	2.63e-150	-	-	-	J	-	-	-	HAD-hyrolase-like
APHAPHFK_01545	9.21e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
APHAPHFK_01546	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
APHAPHFK_01547	1.46e-71	-	-	-	-	-	-	-	-
APHAPHFK_01548	2.69e-169	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
APHAPHFK_01549	4.61e-222	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
APHAPHFK_01550	2.1e-114	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
APHAPHFK_01551	2.26e-143	-	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
APHAPHFK_01552	1.1e-50	-	-	-	-	-	-	-	-
APHAPHFK_01553	6.37e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
APHAPHFK_01554	3.45e-37	-	-	-	-	-	-	-	-
APHAPHFK_01555	3.54e-82	-	-	-	-	-	-	-	-
APHAPHFK_01557	1.6e-145	-	-	-	S	-	-	-	Flavodoxin-like fold
APHAPHFK_01558	1.27e-123	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
APHAPHFK_01559	0.0	-	-	-	L	-	-	-	Transposase DDE domain
APHAPHFK_01560	7.3e-245	mocA	-	-	S	-	-	-	Oxidoreductase
APHAPHFK_01561	1.51e-77	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
APHAPHFK_01562	8.37e-108	-	-	-	L	-	-	-	Transposase DDE domain
APHAPHFK_01563	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
APHAPHFK_01564	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
APHAPHFK_01566	0.0	-	2.4.1.9, 3.4.24.40	GH68	M	ko:K01406,ko:K20811	ko00500,ko01503,map00500,map01503	ko00000,ko00001,ko01000,ko01002	domain protein
APHAPHFK_01568	0.0	-	-	-	-	-	-	-	-
APHAPHFK_01569	0.0	-	-	-	-	-	-	-	-
APHAPHFK_01570	3.62e-246	-	-	-	-	-	-	-	-
APHAPHFK_01571	4.53e-197	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	N-formylglutamate amidohydrolase
APHAPHFK_01572	8.85e-72	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
APHAPHFK_01573	2.18e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
APHAPHFK_01574	1.2e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
APHAPHFK_01575	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
APHAPHFK_01576	2.01e-81	-	-	-	-	-	-	-	-
APHAPHFK_01577	7.13e-110	-	-	-	S	-	-	-	ASCH
APHAPHFK_01578	6.91e-45	-	-	-	-	-	-	-	-
APHAPHFK_01579	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
APHAPHFK_01580	6.01e-268	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
APHAPHFK_01581	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
APHAPHFK_01582	5.93e-128	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
APHAPHFK_01583	2.27e-246	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
APHAPHFK_01585	8.81e-288	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
APHAPHFK_01586	1.89e-226	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
APHAPHFK_01587	1.65e-213	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
APHAPHFK_01588	1.91e-152	yceF	-	-	P	ko:K05794	-	ko00000	membrane
APHAPHFK_01589	1.27e-76	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
APHAPHFK_01590	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
APHAPHFK_01591	1.85e-59	ylxQ	-	-	J	-	-	-	ribosomal protein
APHAPHFK_01592	2.02e-62	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
APHAPHFK_01593	4.49e-278	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
APHAPHFK_01594	3.81e-110	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
APHAPHFK_01595	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
APHAPHFK_01596	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
APHAPHFK_01597	3.52e-292	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
APHAPHFK_01598	4.82e-182	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
APHAPHFK_01599	3.69e-180	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
APHAPHFK_01600	5.98e-114	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
APHAPHFK_01601	1.56e-195	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
APHAPHFK_01602	4.96e-121	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
APHAPHFK_01603	9.72e-166	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
APHAPHFK_01604	3.28e-200	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
APHAPHFK_01605	9.72e-182	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
APHAPHFK_01606	1.29e-63	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
APHAPHFK_01607	1.5e-173	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
APHAPHFK_01608	8.45e-160	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
APHAPHFK_01609	1.03e-303	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
APHAPHFK_01610	7.66e-178	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
APHAPHFK_01611	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
APHAPHFK_01612	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
APHAPHFK_01613	1.39e-40	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
APHAPHFK_01614	3.45e-49	ynzC	-	-	S	-	-	-	UPF0291 protein
APHAPHFK_01615	1.08e-35	-	-	-	-	-	-	-	-
APHAPHFK_01616	2.64e-05	-	-	-	-	-	-	-	-
APHAPHFK_01617	1.16e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
APHAPHFK_01618	2.61e-190	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
APHAPHFK_01619	9.14e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
APHAPHFK_01620	2.2e-51	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
APHAPHFK_01621	2.97e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
APHAPHFK_01622	8.77e-303	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
APHAPHFK_01623	2.45e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
APHAPHFK_01624	3.74e-36	-	-	-	-	-	-	-	-
APHAPHFK_01625	1.12e-69	-	-	-	-	-	-	-	-
APHAPHFK_01626	7.76e-234	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
APHAPHFK_01627	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
APHAPHFK_01628	1.97e-161	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
APHAPHFK_01629	0.0	oppA1	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
APHAPHFK_01630	6.51e-196	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
APHAPHFK_01631	8.93e-223	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
APHAPHFK_01632	1.39e-229	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
APHAPHFK_01633	2.99e-247	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
APHAPHFK_01634	9.22e-49	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
APHAPHFK_01635	1.72e-242	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
APHAPHFK_01636	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
APHAPHFK_01637	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
APHAPHFK_01638	5.83e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
APHAPHFK_01639	3.26e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
APHAPHFK_01640	5.08e-164	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
APHAPHFK_01641	2.81e-149	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
APHAPHFK_01642	1.8e-217	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
APHAPHFK_01643	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
APHAPHFK_01644	3.15e-175	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
APHAPHFK_01645	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
APHAPHFK_01646	1.68e-226	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
APHAPHFK_01647	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
APHAPHFK_01648	6.86e-276	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
APHAPHFK_01649	4.4e-47	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
APHAPHFK_01650	5.09e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
APHAPHFK_01651	2.8e-159	-	-	-	S	ko:K07001	-	ko00000	Patatin-like phospholipase
APHAPHFK_01652	8.07e-68	-	-	-	-	-	-	-	-
APHAPHFK_01653	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
APHAPHFK_01654	3.59e-97	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
APHAPHFK_01655	3.3e-196	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
APHAPHFK_01656	1.23e-190	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
APHAPHFK_01657	2.87e-43	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
APHAPHFK_01658	1.15e-313	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
APHAPHFK_01659	9.8e-197	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
APHAPHFK_01660	9.08e-88	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
APHAPHFK_01661	7.46e-101	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
APHAPHFK_01662	4.27e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
APHAPHFK_01663	6.4e-261	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
APHAPHFK_01664	1.6e-63	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
APHAPHFK_01665	7.21e-74	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
APHAPHFK_01666	1.18e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
APHAPHFK_01667	1.88e-43	-	-	-	-	-	-	-	-
APHAPHFK_01668	1.77e-20	-	-	-	-	-	-	-	-
APHAPHFK_01669	2.31e-298	-	-	-	S	-	-	-	Membrane
APHAPHFK_01671	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
APHAPHFK_01672	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
APHAPHFK_01673	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
APHAPHFK_01674	5.4e-80	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
APHAPHFK_01675	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
APHAPHFK_01676	1.21e-307	ynbB	-	-	P	-	-	-	aluminum resistance
APHAPHFK_01677	1.76e-233	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
APHAPHFK_01678	9.56e-35	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
APHAPHFK_01679	6.47e-95	yqhL	-	-	P	-	-	-	Rhodanese-like protein
APHAPHFK_01680	1.44e-228	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
APHAPHFK_01681	1.37e-54	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
APHAPHFK_01682	3.82e-158	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
APHAPHFK_01683	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
APHAPHFK_01684	0.0	-	-	-	L	-	-	-	Uncharacterised protein family (UPF0236)
APHAPHFK_01685	0.0	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
APHAPHFK_01686	1.91e-70	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
APHAPHFK_01687	8.32e-149	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
APHAPHFK_01688	4.83e-235	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
APHAPHFK_01689	3.99e-167	yvqF	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
APHAPHFK_01690	6.1e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
APHAPHFK_01691	1.45e-149	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
APHAPHFK_01692	1.17e-268	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
APHAPHFK_01693	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
APHAPHFK_01694	4.32e-260	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
APHAPHFK_01695	1.44e-90	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
APHAPHFK_01696	3.09e-122	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
APHAPHFK_01697	7.41e-177	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
APHAPHFK_01698	4.33e-62	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
APHAPHFK_01699	9.37e-230	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
APHAPHFK_01700	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
APHAPHFK_01701	1.01e-157	csrR	-	-	K	-	-	-	response regulator
APHAPHFK_01702	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
APHAPHFK_01703	2.42e-178	-	-	-	M	-	-	-	Peptidase family M23
APHAPHFK_01704	2.82e-302	-	-	-	L	-	-	-	Probable transposase
APHAPHFK_01705	4.98e-24	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
APHAPHFK_01707	8.69e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
APHAPHFK_01708	2.37e-270	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
APHAPHFK_01709	1.24e-180	yqeM	-	-	Q	-	-	-	Methyltransferase
APHAPHFK_01710	1.68e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
APHAPHFK_01711	9.21e-142	yqeK	-	-	H	-	-	-	Hydrolase, HD family
APHAPHFK_01712	1.19e-150	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
APHAPHFK_01713	1.61e-64	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
APHAPHFK_01714	1.96e-276	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
APHAPHFK_01715	4.16e-125	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
APHAPHFK_01716	2.58e-225	ykcA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APHAPHFK_01717	2.35e-244	mhqA_2	-	-	E	ko:K15975	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APHAPHFK_01718	2.16e-156	mhqD	-	-	S	ko:K06999	-	ko00000	Dienelactone hydrolase family
APHAPHFK_01719	7.45e-232	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
APHAPHFK_01720	2.88e-130	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
APHAPHFK_01721	1.44e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
APHAPHFK_01722	1.13e-36	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
APHAPHFK_01723	2.6e-101	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
APHAPHFK_01724	1.37e-94	-	-	-	K	-	-	-	Transcriptional regulator
APHAPHFK_01725	0.0	-	-	-	L	-	-	-	Transposase DDE domain
APHAPHFK_01726	3.74e-299	norB	-	-	EGP	ko:K08170	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
APHAPHFK_01727	7.19e-177	-	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
APHAPHFK_01728	2.23e-165	-	-	-	S	-	-	-	SseB protein N-terminal domain
APHAPHFK_01729	7.13e-87	-	-	-	-	-	-	-	-
APHAPHFK_01730	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
APHAPHFK_01731	1.59e-290	-	-	-	V	ko:K07454	-	ko00000	regulation of methylation-dependent chromatin silencing
APHAPHFK_01732	3.91e-217	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
APHAPHFK_01733	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
APHAPHFK_01734	3.55e-104	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
APHAPHFK_01735	2.42e-133	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
APHAPHFK_01736	5.53e-207	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
APHAPHFK_01737	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
APHAPHFK_01738	1.21e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Inhibitor of apoptosis-promoting Bax1
APHAPHFK_01740	7.99e-253	-	-	-	S	-	-	-	Cell surface protein
APHAPHFK_01742	1.14e-180	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
APHAPHFK_01743	0.0	-	-	-	N	-	-	-	domain, Protein
APHAPHFK_01744	0.0	XK27_00195	-	-	K	-	-	-	Mga helix-turn-helix domain
APHAPHFK_01745	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
APHAPHFK_01746	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
APHAPHFK_01748	8.42e-149	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
APHAPHFK_01749	4.38e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
APHAPHFK_01751	1.11e-154	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
APHAPHFK_01752	3.86e-190	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
APHAPHFK_01753	7.59e-287	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
APHAPHFK_01754	1.5e-171	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APHAPHFK_01755	2.39e-98	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
APHAPHFK_01756	2.79e-77	-	-	-	S	-	-	-	YtxH-like protein
APHAPHFK_01757	2.5e-203	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
APHAPHFK_01758	1.25e-233	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
APHAPHFK_01759	3.88e-73	-	-	-	S	-	-	-	Control of competence regulator ComK, YlbF/YmcA
APHAPHFK_01760	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
APHAPHFK_01761	2.16e-202	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
APHAPHFK_01762	3.31e-98	argR1	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
APHAPHFK_01763	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
APHAPHFK_01765	1.97e-88	-	-	-	-	-	-	-	-
APHAPHFK_01766	4.73e-31	-	-	-	-	-	-	-	-
APHAPHFK_01767	3.26e-226	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate
APHAPHFK_01768	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
APHAPHFK_01769	9.38e-158	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
APHAPHFK_01770	1.03e-105	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
APHAPHFK_01771	7.19e-180	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
APHAPHFK_01772	2.45e-119	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
APHAPHFK_01773	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
APHAPHFK_01774	5.63e-178	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
APHAPHFK_01775	5.84e-157	rrp1	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
APHAPHFK_01776	1.07e-265	-	-	-	T	ko:K19168	-	ko00000,ko02048	His Kinase A (phosphoacceptor) domain
APHAPHFK_01777	1.32e-140	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
APHAPHFK_01778	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5	-	P	ko:K01533,ko:K01534	-	ko00000,ko01000	P-type ATPase
APHAPHFK_01779	9.97e-103	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
APHAPHFK_01780	2.11e-289	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
APHAPHFK_01781	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
APHAPHFK_01782	2.36e-130	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
APHAPHFK_01783	3.89e-241	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
APHAPHFK_01784	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
APHAPHFK_01785	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APHAPHFK_01786	3.56e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APHAPHFK_01787	9.52e-56	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APHAPHFK_01788	6.63e-172	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
APHAPHFK_01789	4.27e-274	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
APHAPHFK_01790	1.04e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
APHAPHFK_01791	2.72e-135	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
APHAPHFK_01793	0.0	iolT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
APHAPHFK_01794	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
APHAPHFK_01795	1.02e-51	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
APHAPHFK_01796	6.69e-39	-	-	-	-	-	-	-	-
APHAPHFK_01797	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
APHAPHFK_01798	2.87e-62	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
APHAPHFK_01799	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
APHAPHFK_01800	1.13e-308	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
APHAPHFK_01801	3.07e-264	yueF	-	-	S	-	-	-	AI-2E family transporter
APHAPHFK_01802	1.96e-98	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
APHAPHFK_01803	1.41e-125	-	-	-	-	-	-	-	-
APHAPHFK_01804	4.26e-135	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
APHAPHFK_01805	2.12e-182	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
APHAPHFK_01806	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
APHAPHFK_01807	2.24e-84	-	-	-	-	-	-	-	-
APHAPHFK_01808	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
APHAPHFK_01809	2.89e-105	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
APHAPHFK_01810	0.0	poxL	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
APHAPHFK_01811	2.23e-281	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
APHAPHFK_01812	1.24e-279	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
APHAPHFK_01813	1.08e-269	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
APHAPHFK_01814	5.09e-66	-	-	-	-	-	-	-	-
APHAPHFK_01815	3.47e-207	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
APHAPHFK_01816	4.44e-134	-	-	-	V	ko:K07448	-	ko00000,ko02048	Restriction endonuclease
APHAPHFK_01817	2.64e-207	-	-	-	G	-	-	-	Aldose 1-epimerase
APHAPHFK_01818	2.37e-271	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
APHAPHFK_01819	8.38e-130	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
APHAPHFK_01821	1.4e-105	-	-	-	K	-	-	-	FR47-like protein
APHAPHFK_01822	7.56e-108	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
APHAPHFK_01823	5.8e-168	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APHAPHFK_01824	4.35e-176	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
APHAPHFK_01825	1.61e-226	XK27_08835	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
APHAPHFK_01826	7.07e-97	-	-	-	-	-	-	-	-
APHAPHFK_01827	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
APHAPHFK_01828	3.03e-277	-	-	-	V	-	-	-	Beta-lactamase
APHAPHFK_01829	7.18e-195	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
APHAPHFK_01830	1.93e-286	-	-	-	V	-	-	-	Beta-lactamase
APHAPHFK_01831	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
APHAPHFK_01832	2.79e-162	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
APHAPHFK_01833	2.49e-278	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
APHAPHFK_01834	1.18e-179	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
APHAPHFK_01835	0.0	yuxL	3.4.19.1	-	E	ko:K01303	-	ko00000,ko01000,ko01002	Prolyl oligopeptidase family
APHAPHFK_01836	0.0	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
APHAPHFK_01837	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
APHAPHFK_01839	1.71e-203	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
APHAPHFK_01840	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
APHAPHFK_01841	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APHAPHFK_01842	2.43e-87	-	-	-	-	-	-	-	-
APHAPHFK_01843	2.4e-97	-	-	-	S	-	-	-	function, without similarity to other proteins
APHAPHFK_01844	0.0	-	-	-	G	-	-	-	MFS/sugar transport protein
APHAPHFK_01845	1.26e-299	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
APHAPHFK_01846	3.89e-75	-	-	-	-	-	-	-	-
APHAPHFK_01847	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
APHAPHFK_01848	3.18e-34	-	-	-	S	-	-	-	Virus attachment protein p12 family
APHAPHFK_01849	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
APHAPHFK_01850	1.12e-131	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA
APHAPHFK_01851	1.88e-174	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
APHAPHFK_01852	1.12e-115	-	-	-	E	-	-	-	AAA domain
APHAPHFK_01855	2.62e-152	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
APHAPHFK_01856	1.95e-118	-	-	-	S	-	-	-	MucBP domain
APHAPHFK_01857	5.24e-113	-	-	-	-	-	-	-	-
APHAPHFK_01860	1.13e-93	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
APHAPHFK_01863	1.45e-46	-	-	-	-	-	-	-	-
APHAPHFK_01864	8.24e-289	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
APHAPHFK_01865	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
APHAPHFK_01866	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
APHAPHFK_01867	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
APHAPHFK_01869	8.38e-170	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
APHAPHFK_01870	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
APHAPHFK_01871	1.96e-126	-	-	-	-	-	-	-	-
APHAPHFK_01872	9.45e-131	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
APHAPHFK_01873	3.49e-244	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
APHAPHFK_01874	8.57e-134	-	-	-	-	-	-	-	-
APHAPHFK_01875	1.43e-25	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
APHAPHFK_01876	6.89e-314	-	-	-	S	-	-	-	Fic/DOC family
APHAPHFK_01877	1.26e-209	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
APHAPHFK_01878	3.59e-201	-	-	-	I	-	-	-	alpha/beta hydrolase fold
APHAPHFK_01879	5.53e-90	-	-	-	-	-	-	-	-
APHAPHFK_01880	8.26e-92	-	-	-	-	-	-	-	-
APHAPHFK_01881	4.37e-206	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
APHAPHFK_01882	6.87e-162	citR	-	-	K	-	-	-	FCD
APHAPHFK_01883	0.0	oadA	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Conserved carboxylase domain
APHAPHFK_01884	4.83e-131	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
APHAPHFK_01885	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
APHAPHFK_01886	1.51e-200	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
APHAPHFK_01887	4.85e-65	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
APHAPHFK_01888	2.93e-235	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
APHAPHFK_01889	4.63e-07	-	-	-	-	-	-	-	-
APHAPHFK_01890	1.6e-250	oadB	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Na+-transporting oxaloacetate decarboxylase beta subunit
APHAPHFK_01891	7.15e-58	oadG	-	-	I	-	-	-	Biotin-requiring enzyme
APHAPHFK_01892	9.87e-70	-	-	-	-	-	-	-	-
APHAPHFK_01893	2.47e-308	citM	-	-	C	ko:K03300	-	ko00000	Citrate transporter
APHAPHFK_01894	4.38e-56	-	-	-	-	-	-	-	-
APHAPHFK_01895	8.4e-132	kptA	-	-	J	ko:K07559	-	ko00000,ko01000,ko03016	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
APHAPHFK_01896	8.5e-116	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
APHAPHFK_01897	2.52e-142	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
APHAPHFK_01898	4.99e-75	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
APHAPHFK_01899	1.46e-133	ORF00048	-	-	-	-	-	-	-
APHAPHFK_01900	4.47e-177	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
APHAPHFK_01901	2.87e-216	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
APHAPHFK_01902	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
APHAPHFK_01903	1.25e-149	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
APHAPHFK_01904	0.0	ypiB	-	-	EGP	-	-	-	Major Facilitator
APHAPHFK_01905	2.1e-163	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
APHAPHFK_01906	2.73e-240	-	-	-	K	-	-	-	Helix-turn-helix domain
APHAPHFK_01907	2.44e-209	-	-	-	S	-	-	-	Alpha beta hydrolase
APHAPHFK_01908	5.73e-82	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
APHAPHFK_01909	6.34e-166	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
APHAPHFK_01910	1.83e-16	-	-	-	-	-	-	-	-
APHAPHFK_01911	1.47e-209	-	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
APHAPHFK_01912	5.22e-255	-	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
APHAPHFK_01913	6.34e-66	-	-	-	-	-	-	-	-
APHAPHFK_01914	3.48e-219	-	-	-	P	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
APHAPHFK_01915	5.52e-215	-	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
APHAPHFK_01916	0.0	-	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
APHAPHFK_01917	4.7e-52	-	-	-	-	-	-	-	-
APHAPHFK_01918	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
APHAPHFK_01919	0.0	-	-	-	V	ko:K06147,ko:K06148,ko:K11085,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter transmembrane region
APHAPHFK_01920	3.93e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
APHAPHFK_01921	0.0	XK27_08510	-	-	L	-	-	-	Type III restriction protein res subunit
APHAPHFK_01922	3.21e-208	-	2.7.1.39	-	S	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Phosphotransferase enzyme family
APHAPHFK_01923	8.09e-160	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
APHAPHFK_01924	0.0	-	-	-	M	-	-	-	LysM domain
APHAPHFK_01926	1.7e-66	lciIC	-	-	K	-	-	-	Helix-turn-helix domain
APHAPHFK_01928	0.0	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
APHAPHFK_01929	0.0	-	-	-	L	-	-	-	Transposase DDE domain
APHAPHFK_01930	2.17e-45	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
APHAPHFK_01931	3.82e-149	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
APHAPHFK_01933	1.29e-58	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
APHAPHFK_01934	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
APHAPHFK_01936	2.34e-240	-	-	-	-	-	-	-	-
APHAPHFK_01937	0.0	-	-	-	L	-	-	-	Transposase DDE domain
APHAPHFK_01940	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
APHAPHFK_01941	3.82e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
APHAPHFK_01942	1.99e-71	-	-	-	-	-	-	-	-
APHAPHFK_01943	3.82e-57	-	-	-	-	-	-	-	-
APHAPHFK_01944	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
APHAPHFK_01945	1.44e-109	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
APHAPHFK_01946	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
APHAPHFK_01947	1.82e-37	-	-	-	-	-	-	-	-
APHAPHFK_01948	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
APHAPHFK_01949	3.98e-230	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
APHAPHFK_01950	3.31e-108	yjhE	-	-	S	-	-	-	Phage tail protein
APHAPHFK_01951	6.51e-305	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
APHAPHFK_01952	3.19e-238	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
APHAPHFK_01953	4.02e-165	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
APHAPHFK_01954	1.76e-220	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
APHAPHFK_01955	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
APHAPHFK_01956	3.26e-175	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APHAPHFK_01957	0.0	-	-	-	E	-	-	-	Amino Acid
APHAPHFK_01958	7.89e-213	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
APHAPHFK_01959	1.12e-304	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
APHAPHFK_01960	2.84e-201	nodB3	-	-	G	-	-	-	Polysaccharide deacetylase
APHAPHFK_01961	1.44e-127	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
APHAPHFK_01962	2.08e-144	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
APHAPHFK_01963	3.45e-315	-	-	-	-	-	-	-	-
APHAPHFK_01964	4.9e-315	-	-	-	-	-	-	-	-
APHAPHFK_01965	1.16e-119	-	-	-	-	-	-	-	-
APHAPHFK_01966	1.93e-206	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
APHAPHFK_01967	3.55e-260	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
APHAPHFK_01968	1.55e-140	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
APHAPHFK_01969	2.26e-210	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
APHAPHFK_01970	5.33e-103	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
APHAPHFK_01971	4.93e-283	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
APHAPHFK_01973	0.0	-	-	-	L	-	-	-	Transposase DDE domain
APHAPHFK_01974	0.0	cps2E	-	-	M	-	-	-	Bacterial sugar transferase
APHAPHFK_01975	1.61e-225	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
APHAPHFK_01976	7.92e-142	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
APHAPHFK_01977	1.18e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
APHAPHFK_01978	6.12e-191	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
APHAPHFK_01979	1.05e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
APHAPHFK_01980	6.79e-222	-	-	-	-	-	-	-	-
APHAPHFK_01982	1.93e-110	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
APHAPHFK_01983	7.71e-14	-	-	-	-	-	-	-	-
APHAPHFK_01984	8.86e-145	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
APHAPHFK_01985	2.96e-91	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
APHAPHFK_01986	1.05e-203	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
APHAPHFK_01987	5.84e-312	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
APHAPHFK_01988	2.89e-19	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
APHAPHFK_01989	4.82e-180	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
APHAPHFK_01990	3.38e-72	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
APHAPHFK_01991	2.2e-222	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
APHAPHFK_01992	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
APHAPHFK_01993	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
APHAPHFK_01994	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
APHAPHFK_01995	1.29e-259	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
APHAPHFK_01996	1.51e-254	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
APHAPHFK_01997	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
APHAPHFK_01998	1.06e-262	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
APHAPHFK_01999	1.8e-180	-	-	-	M	-	-	-	Sortase family
APHAPHFK_02000	3.72e-186	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
APHAPHFK_02001	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
APHAPHFK_02002	0.0	-	-	-	L	-	-	-	Transposase DDE domain
APHAPHFK_02003	3.92e-86	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
APHAPHFK_02004	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
APHAPHFK_02005	5.46e-184	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
APHAPHFK_02006	1.03e-205	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
APHAPHFK_02007	2.92e-259	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
APHAPHFK_02008	2.2e-140	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
APHAPHFK_02009	1.54e-135	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
APHAPHFK_02010	0.0	-	-	-	L	-	-	-	Transposase DDE domain
APHAPHFK_02011	5.71e-48	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
APHAPHFK_02012	1.34e-161	rfbP	-	-	M	-	-	-	Bacterial sugar transferase
APHAPHFK_02013	3.51e-273	-	-	-	M	-	-	-	PFAM Glycosyl transferases group 1
APHAPHFK_02014	4.11e-239	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
APHAPHFK_02015	1.94e-217	-	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 2
APHAPHFK_02016	1e-271	-	-	-	M	-	-	-	Glycosyl transferases group 1
APHAPHFK_02017	1.46e-198	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
APHAPHFK_02018	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
APHAPHFK_02019	1.5e-279	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
APHAPHFK_02020	6.92e-280	-	-	-	-	-	-	-	-
APHAPHFK_02021	1.04e-164	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
APHAPHFK_02022	4.33e-207	epsB	-	-	M	-	-	-	biosynthesis protein
APHAPHFK_02023	2.59e-171	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
APHAPHFK_02024	2.39e-226	-	-	-	K	-	-	-	Protein of unknown function (DUF4065)
APHAPHFK_02025	1.02e-66	-	-	-	S	-	-	-	Motility quorum-sensing regulator, toxin of MqsA
APHAPHFK_02026	5.97e-106	ccl	-	-	S	-	-	-	QueT transporter
APHAPHFK_02027	4.82e-165	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
APHAPHFK_02028	2.98e-49	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
APHAPHFK_02029	3.39e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
APHAPHFK_02030	5.28e-152	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
APHAPHFK_02031	7.74e-232	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
APHAPHFK_02032	2.89e-250	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
APHAPHFK_02033	1.17e-224	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
APHAPHFK_02034	1.99e-208	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
APHAPHFK_02035	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
APHAPHFK_02036	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
APHAPHFK_02037	7.08e-131	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
APHAPHFK_02038	1.4e-172	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
APHAPHFK_02039	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
APHAPHFK_02040	2.94e-191	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
APHAPHFK_02041	7.96e-133	-	-	-	-	-	-	-	-
APHAPHFK_02042	6.5e-71	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
APHAPHFK_02043	5.58e-272	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
APHAPHFK_02044	1.92e-92	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
APHAPHFK_02045	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APHAPHFK_02046	0.0	galA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
APHAPHFK_02047	4.85e-179	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
APHAPHFK_02048	1.9e-176	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
APHAPHFK_02049	0.0	-	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Helix-hairpin-helix containing domain
APHAPHFK_02050	1.79e-144	-	-	-	-	-	-	-	-
APHAPHFK_02051	9.73e-131	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
APHAPHFK_02052	2.91e-187	frlD1	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
APHAPHFK_02053	0.0	-	-	-	G	-	-	-	Phosphodiester glycosidase
APHAPHFK_02055	0.0	hyuA	-	-	EQ	-	-	-	Hydantoinase/oxoprolinase N-terminal region
APHAPHFK_02056	2.43e-264	-	-	-	S	ko:K09703	-	ko00000	Protein of unknown function (DUF917)
APHAPHFK_02057	3.59e-285	-	-	-	F	ko:K10974	-	ko00000,ko02000	Permease for cytosine/purines, uracil, thiamine, allantoin
APHAPHFK_02058	8.04e-168	-	-	-	-	-	-	-	-
APHAPHFK_02059	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF1524)
APHAPHFK_02060	0.0	-	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	Putative ATP-dependent Lon protease
APHAPHFK_02061	0.0	-	-	-	S	-	-	-	PglZ domain
APHAPHFK_02062	0.0	-	-	-	V	-	-	-	Eco57I restriction-modification methylase
APHAPHFK_02063	8.7e-257	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APHAPHFK_02064	0.0	-	-	-	V	-	-	-	Eco57I restriction-modification methylase
APHAPHFK_02065	0.0	-	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
APHAPHFK_02066	8.22e-138	-	-	-	S	-	-	-	Domain of unknown function (DUF1788)
APHAPHFK_02067	1.16e-135	-	-	-	S	-	-	-	Putative inner membrane protein (DUF1819)
APHAPHFK_02068	1.42e-270	-	-	-	-	-	-	-	-
APHAPHFK_02069	0.0	pip	-	-	V	ko:K01421	-	ko00000	domain protein
APHAPHFK_02070	8.03e-133	pip	-	-	V	ko:K01421	-	ko00000	domain protein
APHAPHFK_02071	6.19e-314	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
APHAPHFK_02072	1.2e-132	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
APHAPHFK_02073	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
APHAPHFK_02074	2.14e-232	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
APHAPHFK_02075	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
APHAPHFK_02077	1.41e-208	-	-	-	GM	-	-	-	NmrA-like family
APHAPHFK_02078	8.32e-299	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
APHAPHFK_02079	2.5e-186	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
APHAPHFK_02080	2.72e-197	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
APHAPHFK_02081	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
APHAPHFK_02082	4.77e-100	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
APHAPHFK_02083	9.15e-90	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
APHAPHFK_02084	2.96e-285	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
APHAPHFK_02085	2.03e-164	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
APHAPHFK_02086	1.25e-211	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
APHAPHFK_02087	3.91e-220	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
APHAPHFK_02088	5.61e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
APHAPHFK_02089	3.01e-225	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
APHAPHFK_02090	4.21e-100	-	-	-	K	-	-	-	Winged helix DNA-binding domain
APHAPHFK_02091	7.93e-94	-	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
APHAPHFK_02092	7.3e-246	-	-	-	I	-	-	-	carboxylic ester hydrolase activity
APHAPHFK_02093	7.34e-291	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
APHAPHFK_02094	1.88e-83	-	-	-	P	-	-	-	Rhodanese-like domain
APHAPHFK_02095	2.45e-109	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
APHAPHFK_02096	9.17e-37	-	-	-	-	-	-	-	-
APHAPHFK_02097	8.12e-90	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	MarR family
APHAPHFK_02098	3.25e-13	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
APHAPHFK_02099	8.41e-236	-	-	-	S	-	-	-	Putative esterase
APHAPHFK_02100	9.23e-241	-	-	-	-	-	-	-	-
APHAPHFK_02101	5.56e-136	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
APHAPHFK_02102	7.19e-113	-	-	-	F	-	-	-	NUDIX domain
APHAPHFK_02103	1.15e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
APHAPHFK_02104	1.39e-40	-	-	-	-	-	-	-	-
APHAPHFK_02105	4.05e-201	-	-	-	S	-	-	-	zinc-ribbon domain
APHAPHFK_02106	5.46e-258	pbpX	-	-	V	-	-	-	Beta-lactamase
APHAPHFK_02107	1.77e-239	ydbI	-	-	K	-	-	-	AI-2E family transporter
APHAPHFK_02108	2.05e-164	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
APHAPHFK_02109	3.45e-86	gtcA2	-	-	S	-	-	-	Teichoic acid glycosylation protein
APHAPHFK_02110	0.0	-	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
APHAPHFK_02111	3.5e-219	gbuC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
APHAPHFK_02112	1.23e-190	gbuB	-	-	E	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
APHAPHFK_02113	1.85e-284	gbuA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
APHAPHFK_02114	9.41e-175	sfsA	-	-	S	ko:K06206	-	ko00000	Belongs to the SfsA family
APHAPHFK_02115	1.5e-95	usp1	-	-	T	-	-	-	Universal stress protein family
APHAPHFK_02116	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
APHAPHFK_02117	8.12e-205	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
APHAPHFK_02118	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
APHAPHFK_02119	5.83e-293	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
APHAPHFK_02120	0.0	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
APHAPHFK_02121	4.25e-287	floL	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	SPFH domain / Band 7 family
APHAPHFK_02122	1.15e-89	-	-	-	-	-	-	-	-
APHAPHFK_02123	7.76e-130	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
APHAPHFK_02124	6.51e-114	-	-	-	L	-	-	-	Transposase
APHAPHFK_02125	4.87e-50	-	-	-	L	-	-	-	Transposase
APHAPHFK_02126	5.61e-83	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
APHAPHFK_02127	5.89e-231	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APHAPHFK_02128	9.79e-279	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
APHAPHFK_02129	4.87e-50	-	-	-	L	-	-	-	Transposase
APHAPHFK_02130	6.51e-114	-	-	-	L	-	-	-	Transposase
APHAPHFK_02131	2.42e-164	WQ51_05710	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
APHAPHFK_02132	5.29e-195	-	-	-	S	-	-	-	Alpha/beta hydrolase family
APHAPHFK_02133	5.33e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
APHAPHFK_02134	4.31e-239	-	-	-	V	ko:K01421	-	ko00000	domain protein
APHAPHFK_02135	0.0	-	-	-	L	-	-	-	Transposase DDE domain
APHAPHFK_02136	5.37e-221	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
APHAPHFK_02137	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
APHAPHFK_02138	1.91e-178	ydeA	-	-	S	-	-	-	DJ-1/PfpI family
APHAPHFK_02139	4.32e-104	yosT	-	-	L	-	-	-	Bacterial transcription activator, effector binding domain
APHAPHFK_02140	2.25e-265	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
APHAPHFK_02141	4.33e-206	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
APHAPHFK_02142	2.29e-226	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
APHAPHFK_02143	1.35e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
APHAPHFK_02144	1.04e-213	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
APHAPHFK_02145	1.52e-282	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
APHAPHFK_02146	3.94e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
APHAPHFK_02147	5.32e-208	CcmA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
APHAPHFK_02148	1.19e-149	-	-	-	I	-	-	-	ABC-2 family transporter protein
APHAPHFK_02149	1.76e-188	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	reductase
APHAPHFK_02150	5.07e-238	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
APHAPHFK_02151	1.75e-119	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
APHAPHFK_02152	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
APHAPHFK_02153	9.88e-205	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
APHAPHFK_02154	0.0	msbA9	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
APHAPHFK_02155	0.0	cydD1	-	-	CO	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
APHAPHFK_02156	2.22e-98	-	-	-	S	-	-	-	NusG domain II
APHAPHFK_02157	5.79e-233	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
APHAPHFK_02158	1.02e-33	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
APHAPHFK_02160	1.14e-153	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
APHAPHFK_02161	2.05e-66	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
APHAPHFK_02162	1.8e-218	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
APHAPHFK_02163	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
APHAPHFK_02164	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
APHAPHFK_02165	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
APHAPHFK_02166	6.13e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
APHAPHFK_02167	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
APHAPHFK_02168	2.1e-306	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
APHAPHFK_02169	2.92e-233	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
APHAPHFK_02170	1.18e-50	-	-	-	-	-	-	-	-
APHAPHFK_02171	5.18e-114	-	-	-	-	-	-	-	-
APHAPHFK_02172	1.57e-34	-	-	-	-	-	-	-	-
APHAPHFK_02173	1.2e-208	-	-	-	EG	-	-	-	EamA-like transporter family
APHAPHFK_02174	2.08e-145	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
APHAPHFK_02175	2.35e-101	usp5	-	-	T	-	-	-	universal stress protein
APHAPHFK_02176	8.34e-86	-	-	-	K	-	-	-	Helix-turn-helix domain
APHAPHFK_02177	3.36e-185	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
APHAPHFK_02178	5.06e-282	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Domain of unknown function (DUF1730)
APHAPHFK_02179	1.8e-83	-	-	-	-	-	-	-	-
APHAPHFK_02180	3e-115	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
APHAPHFK_02182	1.28e-132	-	-	-	Q	-	-	-	methyltransferase
APHAPHFK_02183	2.96e-146	-	-	-	T	-	-	-	Sh3 type 3 domain protein
APHAPHFK_02184	1.07e-148	-	-	-	F	-	-	-	glutamine amidotransferase
APHAPHFK_02185	4.85e-180	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
APHAPHFK_02186	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
APHAPHFK_02187	2.69e-185	-	-	-	S	-	-	-	Alpha beta hydrolase
APHAPHFK_02188	9.69e-254	-	-	-	I	-	-	-	Acyltransferase
APHAPHFK_02189	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
APHAPHFK_02190	2.27e-109	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
APHAPHFK_02191	1.05e-125	maf	-	-	D	ko:K06287	-	ko00000	nucleoside-triphosphate diphosphatase activity
APHAPHFK_02192	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
APHAPHFK_02193	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
APHAPHFK_02194	0.0	ydaO	-	-	E	-	-	-	amino acid
APHAPHFK_02195	7.56e-75	-	-	-	S	-	-	-	Domain of unknown function (DUF1827)
APHAPHFK_02196	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
APHAPHFK_02197	1.7e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
APHAPHFK_02198	4.3e-143	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
APHAPHFK_02199	1.43e-251	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
APHAPHFK_02200	3.24e-250	-	-	-	-	-	-	-	-
APHAPHFK_02201	4.35e-206	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
APHAPHFK_02202	7.06e-81	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
APHAPHFK_02203	7.76e-152	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
APHAPHFK_02204	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
APHAPHFK_02205	6.92e-66	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
APHAPHFK_02206	4.36e-240	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
APHAPHFK_02207	1.29e-128	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
APHAPHFK_02208	1.33e-168	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
APHAPHFK_02209	1.23e-160	-	-	-	-	-	-	-	-
APHAPHFK_02210	1.32e-16	-	-	-	-	-	-	-	-
APHAPHFK_02211	4.02e-116	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
APHAPHFK_02212	3.04e-232	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
APHAPHFK_02213	9.48e-186	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
APHAPHFK_02214	5.67e-197	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
APHAPHFK_02215	2.27e-75	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
APHAPHFK_02216	2.04e-226	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
APHAPHFK_02217	2.31e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
APHAPHFK_02218	3.17e-150	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
APHAPHFK_02219	1.35e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
APHAPHFK_02220	2.17e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
APHAPHFK_02221	2.29e-50	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
APHAPHFK_02222	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
APHAPHFK_02223	6.49e-116	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
APHAPHFK_02224	2.82e-65	-	-	-	-	-	-	-	-
APHAPHFK_02225	5.76e-140	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
APHAPHFK_02226	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
APHAPHFK_02227	9.88e-91	-	-	-	-	-	-	-	-
APHAPHFK_02228	2.2e-223	ccpB	-	-	K	-	-	-	lacI family
APHAPHFK_02229	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
APHAPHFK_02230	4.14e-202	-	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
APHAPHFK_02231	3.91e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
APHAPHFK_02232	6.19e-109	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
APHAPHFK_02233	1.04e-287	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
APHAPHFK_02234	1.2e-201	-	-	-	K	-	-	-	acetyltransferase
APHAPHFK_02235	8.38e-118	-	-	-	-	-	-	-	-
APHAPHFK_02236	1.07e-283	yceI	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
APHAPHFK_02237	8.7e-317	-	-	-	-	-	-	-	-
APHAPHFK_02238	6.93e-64	-	-	-	-	-	-	-	-
APHAPHFK_02239	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
APHAPHFK_02240	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
APHAPHFK_02241	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
APHAPHFK_02242	6.11e-129	yqaB	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
APHAPHFK_02243	1.33e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
APHAPHFK_02244	1.97e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
APHAPHFK_02245	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
APHAPHFK_02246	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
APHAPHFK_02247	2.14e-123	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobalamin adenosyltransferase
APHAPHFK_02248	2.2e-117	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
APHAPHFK_02249	2.89e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
APHAPHFK_02250	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
APHAPHFK_02251	6.51e-103	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	nucleoside 2-deoxyribosyltransferase
APHAPHFK_02252	5.74e-204	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
APHAPHFK_02253	8e-131	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
APHAPHFK_02254	2.53e-31	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
APHAPHFK_02255	3.75e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
APHAPHFK_02256	4.78e-222	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
APHAPHFK_02257	3.19e-212	menA	2.5.1.74	-	M	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
APHAPHFK_02258	2.9e-252	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
APHAPHFK_02259	2.67e-295	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
APHAPHFK_02260	7.5e-190	cad	-	-	S	ko:K20379	ko02024,map02024	ko00000,ko00001	FMN_bind
APHAPHFK_02261	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
APHAPHFK_02262	2.87e-106	-	-	-	S	-	-	-	NusG domain II
APHAPHFK_02263	7.23e-128	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
APHAPHFK_02264	9.42e-232	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
APHAPHFK_02265	1.21e-109	-	-	-	-	-	-	-	-
APHAPHFK_02266	1.2e-196	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
APHAPHFK_02267	1.18e-124	-	-	-	-	-	-	-	-
APHAPHFK_02268	3.21e-212	-	-	-	-	-	-	-	-
APHAPHFK_02269	5.07e-203	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
APHAPHFK_02270	7.53e-285	-	-	-	-	-	-	-	-
APHAPHFK_02271	3.25e-253	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
APHAPHFK_02272	5.66e-159	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	Rossmann-like domain
APHAPHFK_02273	7.66e-251	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
APHAPHFK_02274	1.45e-126	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
APHAPHFK_02275	5.24e-185	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
APHAPHFK_02276	2.79e-97	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
APHAPHFK_02277	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
APHAPHFK_02278	1.16e-208	-	-	-	K	-	-	-	sequence-specific DNA binding
APHAPHFK_02279	4.53e-133	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
APHAPHFK_02280	5.9e-192	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
APHAPHFK_02281	1.05e-135	-	-	-	-	-	-	-	-
APHAPHFK_02283	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
APHAPHFK_02284	4.13e-190	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
APHAPHFK_02285	2.37e-227	-	-	-	S	-	-	-	Membrane
APHAPHFK_02286	3.03e-83	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
APHAPHFK_02287	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
APHAPHFK_02288	7.55e-302	inlJ	-	-	M	-	-	-	MucBP domain
APHAPHFK_02289	2.83e-151	-	-	-	K	-	-	-	sequence-specific DNA binding
APHAPHFK_02290	1.06e-258	yacL	-	-	S	-	-	-	domain protein
APHAPHFK_02291	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
APHAPHFK_02292	4.49e-130	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTPase
APHAPHFK_02293	5.8e-66	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
APHAPHFK_02294	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
APHAPHFK_02295	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
APHAPHFK_02296	4.64e-255	-	-	-	-	-	-	-	-
APHAPHFK_02297	3.39e-275	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
APHAPHFK_02298	1.79e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
APHAPHFK_02299	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
APHAPHFK_02300	0.0	ppdK	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the PEP-utilizing enzyme family
APHAPHFK_02301	2.02e-120	ccpN	-	-	K	-	-	-	Domain in cystathionine beta-synthase and other proteins.
APHAPHFK_02302	9.8e-158	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
APHAPHFK_02303	1.4e-259	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
APHAPHFK_02304	5.45e-61	-	-	-	-	-	-	-	-
APHAPHFK_02305	3.6e-266	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
APHAPHFK_02306	9.49e-26	-	-	-	S	-	-	-	CsbD-like
APHAPHFK_02310	2.13e-44	-	-	-	-	-	-	-	-
APHAPHFK_02311	7.81e-46	-	-	-	-	-	-	-	-
APHAPHFK_02312	4.93e-286	-	-	-	EGP	-	-	-	Transmembrane secretion effector
APHAPHFK_02313	4.09e-289	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
APHAPHFK_02314	7.14e-192	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
APHAPHFK_02316	2.13e-124	-	-	-	-	-	-	-	-
APHAPHFK_02317	2.19e-184	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
APHAPHFK_02318	0.0	-	-	-	M	-	-	-	Cna protein B-type domain
APHAPHFK_02319	0.0	-	-	-	M	-	-	-	domain protein
APHAPHFK_02320	0.0	-	-	-	M	-	-	-	domain protein
APHAPHFK_02321	4.45e-133	-	-	-	-	-	-	-	-
APHAPHFK_02322	2.68e-295	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
APHAPHFK_02323	2.52e-265	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
APHAPHFK_02324	2.91e-146	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
APHAPHFK_02325	5.62e-75	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
APHAPHFK_02326	4.99e-179	-	-	-	-	-	-	-	-
APHAPHFK_02327	3.12e-176	-	-	-	-	-	-	-	-
APHAPHFK_02328	3.12e-61	-	-	-	S	-	-	-	Enterocin A Immunity
APHAPHFK_02329	1.12e-239	tas	-	-	C	-	-	-	Aldo/keto reductase family
APHAPHFK_02330	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
APHAPHFK_02331	5.9e-78	-	-	-	-	-	-	-	-
APHAPHFK_02332	6.29e-307	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
APHAPHFK_02333	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
APHAPHFK_02335	6.26e-289	comD	2.7.13.3	-	T	ko:K07706,ko:K12294	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APHAPHFK_02336	3.25e-180	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
APHAPHFK_02339	1.16e-62	-	-	-	S	-	-	-	Enterocin A Immunity
APHAPHFK_02340	1.93e-31	-	-	-	-	-	-	-	-
APHAPHFK_02344	2.86e-177	-	-	-	S	-	-	-	CAAX protease self-immunity
APHAPHFK_02345	6.02e-94	-	-	-	K	-	-	-	Transcriptional regulator
APHAPHFK_02346	0.0	norB	-	-	EGP	ko:K08170	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
APHAPHFK_02347	6.33e-72	-	-	-	-	-	-	-	-
APHAPHFK_02348	1.36e-72	-	-	-	S	-	-	-	Enterocin A Immunity
APHAPHFK_02349	7.17e-232	ydhF	-	-	S	-	-	-	Aldo keto reductase
APHAPHFK_02350	1.28e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
APHAPHFK_02351	1.18e-276	yqiG	-	-	C	-	-	-	Oxidoreductase
APHAPHFK_02352	1.98e-34	-	-	-	S	-	-	-	Short C-terminal domain
APHAPHFK_02353	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
APHAPHFK_02354	5.67e-175	-	-	-	-	-	-	-	-
APHAPHFK_02355	4.49e-26	-	-	-	-	-	-	-	-
APHAPHFK_02356	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
APHAPHFK_02357	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
APHAPHFK_02358	4.42e-84	-	-	-	-	-	-	-	-
APHAPHFK_02359	1.17e-305	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
APHAPHFK_02360	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
APHAPHFK_02361	2.5e-34	-	-	-	-	-	-	-	-
APHAPHFK_02362	2.06e-145	-	-	-	P	-	-	-	Cation efflux family
APHAPHFK_02363	1.68e-67	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
APHAPHFK_02364	3.81e-225	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
APHAPHFK_02365	9.44e-186	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
APHAPHFK_02366	4.8e-170	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
APHAPHFK_02367	8.32e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
APHAPHFK_02368	1.17e-215	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
APHAPHFK_02369	1.4e-152	-	-	-	GM	-	-	-	NmrA-like family
APHAPHFK_02370	2.63e-113	-	-	-	-	-	-	-	-
APHAPHFK_02371	5.12e-212	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
APHAPHFK_02372	7.32e-28	-	-	-	-	-	-	-	-
APHAPHFK_02374	9.85e-72	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
APHAPHFK_02375	9.16e-91	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
APHAPHFK_02376	0.0	-	-	-	G	ko:K03292,ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
APHAPHFK_02377	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase concanavalin-like domain
APHAPHFK_02378	6.75e-220	ssuA	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	NMT1-like family
APHAPHFK_02379	0.0	-	6.2.1.48	-	IQ	ko:K02182	-	ko00000,ko01000	AMP-binding enzyme C-terminal domain
APHAPHFK_02380	1.25e-301	-	-	-	I	-	-	-	Acyltransferase family
APHAPHFK_02381	4.26e-157	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
APHAPHFK_02382	5.24e-191	ssuC	-	-	U	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
APHAPHFK_02383	7.77e-159	-	-	-	S	-	-	-	B3/4 domain
APHAPHFK_02384	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
APHAPHFK_02385	0.0	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
APHAPHFK_02386	3.91e-268	-	-	-	EGP	-	-	-	Transmembrane secretion effector
APHAPHFK_02387	2.69e-196	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
APHAPHFK_02388	2.96e-114	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
APHAPHFK_02389	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
APHAPHFK_02390	4.23e-104	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
APHAPHFK_02391	4.31e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
APHAPHFK_02392	1.06e-237	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
APHAPHFK_02393	9.39e-167	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
APHAPHFK_02394	1.28e-45	-	-	-	-	-	-	-	-
APHAPHFK_02395	6.34e-178	tipA	-	-	K	-	-	-	TipAS antibiotic-recognition domain
APHAPHFK_02396	6.9e-179	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
APHAPHFK_02397	5.43e-185	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APHAPHFK_02398	4.3e-203	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APHAPHFK_02399	3.44e-199	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APHAPHFK_02400	5.68e-156	-	-	-	-	-	-	-	-
APHAPHFK_02401	2.94e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
APHAPHFK_02402	1.8e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APHAPHFK_02403	3.82e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
APHAPHFK_02404	2.66e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
APHAPHFK_02405	6.38e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
APHAPHFK_02406	4.15e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
APHAPHFK_02407	3.86e-157	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
APHAPHFK_02408	1.15e-297	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
APHAPHFK_02409	1.42e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
APHAPHFK_02410	1.83e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
APHAPHFK_02411	8.15e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
APHAPHFK_02412	5.63e-77	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
APHAPHFK_02413	3.7e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
APHAPHFK_02414	1.32e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
APHAPHFK_02415	1.23e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
APHAPHFK_02416	1.67e-66	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
APHAPHFK_02417	1.73e-77	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
APHAPHFK_02418	1.7e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
APHAPHFK_02419	4.53e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
APHAPHFK_02420	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
APHAPHFK_02421	2.92e-153	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
APHAPHFK_02422	4.5e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
APHAPHFK_02423	5.26e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
APHAPHFK_02424	2.07e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
APHAPHFK_02425	5.07e-62	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
APHAPHFK_02426	1.7e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
APHAPHFK_02427	1.4e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
APHAPHFK_02428	1.09e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
APHAPHFK_02429	1.26e-90	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
APHAPHFK_02430	5.85e-139	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
APHAPHFK_02431	7.4e-254	-	-	-	K	-	-	-	WYL domain
APHAPHFK_02432	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
APHAPHFK_02433	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
APHAPHFK_02434	3.18e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
APHAPHFK_02435	1.21e-110	-	3.4.23.43	-	-	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	-
APHAPHFK_02436	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APHAPHFK_02437	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APHAPHFK_02438	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
APHAPHFK_02439	7.17e-104	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
APHAPHFK_02449	1.13e-93	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
APHAPHFK_02452	1.45e-46	-	-	-	-	-	-	-	-
APHAPHFK_02453	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
APHAPHFK_02454	1.12e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
APHAPHFK_02455	5.97e-208	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
APHAPHFK_02456	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
APHAPHFK_02457	2.04e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
APHAPHFK_02458	5.45e-314	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
APHAPHFK_02459	6.08e-107	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
APHAPHFK_02460	1.87e-84	divIC	-	-	D	ko:K05589,ko:K13052	-	ko00000,ko03036	cell cycle
APHAPHFK_02461	2.33e-52	yabO	-	-	J	-	-	-	S4 domain protein
APHAPHFK_02462	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
APHAPHFK_02463	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
APHAPHFK_02464	1.05e-131	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
APHAPHFK_02465	1.02e-231	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
APHAPHFK_02466	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
APHAPHFK_02467	6.37e-125	padR	-	-	K	-	-	-	Transcriptional regulator PadR-like family
APHAPHFK_02468	0.0	-	-	-	S	ko:K01421	-	ko00000	ABC-2 family transporter protein
APHAPHFK_02469	4.08e-149	-	-	-	S	-	-	-	Flavodoxin-like fold
APHAPHFK_02470	1.9e-154	-	-	-	S	-	-	-	(CBS) domain
APHAPHFK_02471	2.06e-168	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
APHAPHFK_02472	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
APHAPHFK_02473	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
APHAPHFK_02474	5.65e-113	queT	-	-	S	-	-	-	QueT transporter
APHAPHFK_02476	2.32e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
APHAPHFK_02477	5.46e-51	-	-	-	-	-	-	-	-
APHAPHFK_02478	1.5e-278	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
APHAPHFK_02479	2.25e-83	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
APHAPHFK_02480	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
APHAPHFK_02481	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
APHAPHFK_02482	1.07e-190	-	-	-	-	-	-	-	-
APHAPHFK_02483	2.34e-160	-	-	-	S	-	-	-	Tetratricopeptide repeat
APHAPHFK_02484	1.9e-160	-	-	-	-	-	-	-	-
APHAPHFK_02485	1.62e-96	-	-	-	-	-	-	-	-
APHAPHFK_02486	3.24e-57	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
APHAPHFK_02487	3.31e-300	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
APHAPHFK_02488	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
APHAPHFK_02489	4.02e-282	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
APHAPHFK_02492	1.28e-196	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
APHAPHFK_02493	2.69e-103	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
APHAPHFK_02494	1.21e-103	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
APHAPHFK_02496	2.07e-202	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
APHAPHFK_02497	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
APHAPHFK_02498	1.53e-107	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
APHAPHFK_02499	7.8e-240	-	-	-	S	-	-	-	DUF218 domain
APHAPHFK_02500	1.4e-78	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
APHAPHFK_02501	1.66e-100	-	-	-	-	-	-	-	-
APHAPHFK_02502	1.39e-70	nudA	-	-	S	-	-	-	ASCH
APHAPHFK_02503	2.2e-225	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
APHAPHFK_02504	2.22e-297	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
APHAPHFK_02505	2.34e-284	ysaA	-	-	V	-	-	-	RDD family
APHAPHFK_02506	1.01e-193	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
APHAPHFK_02507	1.84e-154	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APHAPHFK_02508	2.5e-159	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
APHAPHFK_02509	6.67e-204	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
APHAPHFK_02510	4.56e-211	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
APHAPHFK_02511	4.13e-51	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
APHAPHFK_02512	1.06e-201	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
APHAPHFK_02513	2.76e-129	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
APHAPHFK_02514	6.41e-190	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
APHAPHFK_02515	9.15e-105	manR	2.7.1.194, 2.7.1.200, 2.7.1.202	-	G	ko:K02538,ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491	ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	phosphoenolpyruvate-dependent sugar phosphotransferase system
APHAPHFK_02516	7.82e-239	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
APHAPHFK_02517	5.19e-222	yqhA	-	-	G	-	-	-	Aldose 1-epimerase
APHAPHFK_02518	1.05e-162	-	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
APHAPHFK_02519	1.22e-216	-	-	-	T	-	-	-	GHKL domain
APHAPHFK_02520	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
APHAPHFK_02521	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
APHAPHFK_02522	9.64e-42	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
APHAPHFK_02523	2.62e-89	-	-	-	-	-	-	-	-
APHAPHFK_02524	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
APHAPHFK_02525	1.15e-222	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
APHAPHFK_02527	2.52e-197	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
APHAPHFK_02528	1.09e-118	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
APHAPHFK_02529	1.8e-217	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
APHAPHFK_02530	5.76e-140	yiiE	-	-	S	-	-	-	Protein of unknown function (DUF1211)
APHAPHFK_02531	1.19e-166	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
APHAPHFK_02532	7.77e-25	-	-	-	-	-	-	-	-
APHAPHFK_02533	1.37e-220	-	-	-	-	-	-	-	-
APHAPHFK_02534	6.73e-127	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
APHAPHFK_02535	9.28e-52	-	-	-	-	-	-	-	-
APHAPHFK_02536	3.46e-219	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
APHAPHFK_02537	1e-220	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
APHAPHFK_02538	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
APHAPHFK_02539	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
APHAPHFK_02540	1.01e-223	ydhF	-	-	S	-	-	-	Aldo keto reductase
APHAPHFK_02541	5.3e-201	-	-	-	Q	-	-	-	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
APHAPHFK_02542	6.79e-120	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
APHAPHFK_02543	5.55e-304	dinF	-	-	V	-	-	-	MatE
APHAPHFK_02545	1.36e-142	-	-	-	S	ko:K06872	-	ko00000	TPM domain
APHAPHFK_02546	5.07e-134	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
APHAPHFK_02547	6.02e-246	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
APHAPHFK_02548	1.19e-104	-	-	-	-	-	-	-	-
APHAPHFK_02549	7.3e-32	-	-	-	-	-	-	-	-
APHAPHFK_02551	6.36e-153	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
APHAPHFK_02553	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
APHAPHFK_02554	1.09e-227	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
APHAPHFK_02555	0.0	choS	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
APHAPHFK_02557	0.0	-	-	-	L	-	-	-	DNA helicase
APHAPHFK_02558	2.51e-195	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
APHAPHFK_02559	4.47e-229	ydiA	-	-	P	ko:K11041	ko05150,map05150	ko00000,ko00001,ko02042	Voltage-dependent anion channel
APHAPHFK_02560	8e-177	yadH	-	-	V	ko:K01992,ko:K09694	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
APHAPHFK_02561	2.2e-173	cylA	-	-	V	ko:K01990,ko:K09695,ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
APHAPHFK_02562	1.19e-167	ydfF	-	-	K	-	-	-	Transcriptional
APHAPHFK_02563	3.81e-142	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
APHAPHFK_02565	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
APHAPHFK_02566	1.82e-144	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
APHAPHFK_02567	4.69e-94	-	-	-	K	-	-	-	MarR family
APHAPHFK_02568	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
APHAPHFK_02569	1.12e-246	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
APHAPHFK_02570	9.32e-184	-	-	-	S	-	-	-	hydrolase
APHAPHFK_02571	3.33e-78	-	-	-	-	-	-	-	-
APHAPHFK_02572	1.71e-17	-	-	-	-	-	-	-	-
APHAPHFK_02573	8.99e-157	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
APHAPHFK_02574	3.55e-163	gpmB	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
APHAPHFK_02575	2.42e-195	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
APHAPHFK_02576	1.38e-117	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
APHAPHFK_02577	2.17e-213	-	-	-	K	-	-	-	LysR substrate binding domain
APHAPHFK_02578	7.67e-294	-	-	-	EK	-	-	-	Aminotransferase, class I
APHAPHFK_02580	1.34e-62	-	-	-	-	-	-	-	-
APHAPHFK_02581	5.18e-75	-	-	-	-	-	-	-	-
APHAPHFK_02582	3.1e-254	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
APHAPHFK_02583	4.38e-150	ydfK	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
APHAPHFK_02584	6.36e-117	-	-	-	-	-	-	-	-
APHAPHFK_02588	0.0	fruC	2.7.1.202	-	GT	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APHAPHFK_02589	6.04e-220	fruK-1	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
APHAPHFK_02590	1e-168	rpl	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
APHAPHFK_02591	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
APHAPHFK_02592	2.81e-177	-	-	-	K	-	-	-	UTRA domain
APHAPHFK_02593	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
APHAPHFK_02594	1.58e-208	-	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
APHAPHFK_02595	2.19e-181	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
APHAPHFK_02596	6.12e-191	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
APHAPHFK_02597	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
APHAPHFK_02598	1.32e-132	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
APHAPHFK_02599	4.17e-314	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
APHAPHFK_02600	2.07e-206	-	-	-	K	-	-	-	LysR substrate binding domain
APHAPHFK_02601	3.13e-99	-	-	-	-	-	-	-	-
APHAPHFK_02602	2.37e-95	-	-	-	K	-	-	-	Transcriptional regulator
APHAPHFK_02603	7.23e-316	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
APHAPHFK_02604	1.77e-130	-	-	-	-	-	-	-	-
APHAPHFK_02605	2.53e-287	dgoD	4.2.1.6, 4.2.1.8	-	M	ko:K01684,ko:K08323	ko00040,ko00052,ko01100,ko01120,map00040,map00052,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Mandelate racemase muconate lactonizing enzyme
APHAPHFK_02606	2.82e-314	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
APHAPHFK_02607	1.18e-60	sgcB	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
APHAPHFK_02608	5.47e-103	-	2.7.1.200	-	GT	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APHAPHFK_02609	2.83e-145	-	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
APHAPHFK_02610	0.0	-	-	-	G	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APHAPHFK_02612	1.84e-65	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
APHAPHFK_02613	3.22e-65	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
APHAPHFK_02614	0.0	bgl	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
APHAPHFK_02615	5.29e-206	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
APHAPHFK_02616	0.0	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
APHAPHFK_02617	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	hydrolase, family 38
APHAPHFK_02618	0.0	-	-	-	L	-	-	-	Transposase DDE domain
APHAPHFK_02619	7.79e-189	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
APHAPHFK_02620	0.0	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APHAPHFK_02621	5.68e-175	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
APHAPHFK_02622	5e-174	yulB	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
APHAPHFK_02623	1.1e-186	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
APHAPHFK_02624	2.28e-102	fucU	5.1.3.29	-	G	ko:K02431	-	ko00000,ko01000	RbsD / FucU transport protein family
APHAPHFK_02625	5.31e-301	xylT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
APHAPHFK_02626	0.0	rhaB	2.7.1.5	-	G	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, N-terminal domain
APHAPHFK_02627	0.0	fucI	5.3.1.25, 5.3.1.3	-	G	ko:K01818	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Converts the aldose L-fucose into the corresponding ketose L-fuculose
APHAPHFK_02628	6.49e-213	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
APHAPHFK_02629	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	L-rhamnose isomerase (RhaA)
APHAPHFK_02630	1.04e-74	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
APHAPHFK_02631	0.0	rhaB	2.7.1.5	-	F	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
APHAPHFK_02632	0.0	iolF	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
APHAPHFK_02633	8.93e-249	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
APHAPHFK_02634	5.2e-276	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
APHAPHFK_02635	4.88e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
APHAPHFK_02636	6.29e-162	-	-	-	-	-	-	-	-
APHAPHFK_02637	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
APHAPHFK_02638	2.69e-196	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
APHAPHFK_02639	5.98e-114	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
APHAPHFK_02640	5.89e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
APHAPHFK_02641	4.19e-65	-	-	-	-	-	-	-	-
APHAPHFK_02642	0.0	-	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
APHAPHFK_02643	0.0	-	2.7.1.199, 2.7.1.208	-	G	ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
APHAPHFK_02645	1.5e-168	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
APHAPHFK_02646	3e-108	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
APHAPHFK_02648	4.82e-178	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
APHAPHFK_02649	1.3e-261	selA	2.9.1.1	-	H	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	L-seryl-tRNA selenium transferase
APHAPHFK_02650	1.28e-276	dho	3.5.2.3	-	S	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase family
APHAPHFK_02651	3.36e-153	-	-	-	S	-	-	-	Domain of unknown function (DUF4310)
APHAPHFK_02652	2.89e-177	-	-	-	S	-	-	-	Domain of unknown function (DUF4311)
APHAPHFK_02653	1.66e-75	-	-	-	S	-	-	-	Domain of unknown function (DUF4312)
APHAPHFK_02654	1.23e-80	-	-	-	S	-	-	-	Glycine-rich SFCGS
APHAPHFK_02655	1.39e-72	-	-	-	S	-	-	-	PRD domain
APHAPHFK_02656	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
APHAPHFK_02657	2.06e-159	-	-	-	H	-	-	-	Pfam:Transaldolase
APHAPHFK_02658	8.61e-85	-	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
APHAPHFK_02659	3.4e-255	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
APHAPHFK_02660	1.43e-131	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
APHAPHFK_02661	1.52e-114	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
APHAPHFK_02662	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
APHAPHFK_02663	2.05e-185	srlD	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
APHAPHFK_02664	1.83e-176	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
APHAPHFK_02665	1.76e-194	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
APHAPHFK_02666	3.1e-215	sga	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
APHAPHFK_02667	3.66e-177	-	-	-	K	-	-	-	DeoR C terminal sensor domain
APHAPHFK_02668	3.7e-148	ulaD	4.1.1.85, 4.1.2.43	-	G	ko:K03078,ko:K08093	ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
APHAPHFK_02669	6.78e-61	sgaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
APHAPHFK_02670	0.0	sgaT	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
APHAPHFK_02671	4.19e-106	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APHAPHFK_02672	3.1e-273	ulaG	-	-	S	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Beta-lactamase superfamily domain
APHAPHFK_02673	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
APHAPHFK_02674	9.75e-59	-	-	-	-	-	-	-	-
APHAPHFK_02675	3.17e-205	-	-	-	GK	-	-	-	ROK family
APHAPHFK_02676	1.57e-232	asnA2	3.5.1.1	-	E	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
APHAPHFK_02677	0.0	-	-	-	E	-	-	-	Peptidase family M20/M25/M40
APHAPHFK_02678	1.5e-169	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
APHAPHFK_02679	4.11e-273	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
APHAPHFK_02680	2.07e-265	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
APHAPHFK_02681	3.55e-127	-	-	-	S	-	-	-	Domain of unknown function (DUF4428)
APHAPHFK_02682	0.0	-	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
APHAPHFK_02683	5.92e-262	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
APHAPHFK_02684	1.71e-199	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
APHAPHFK_02685	4.28e-177	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
APHAPHFK_02686	1.97e-107	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
APHAPHFK_02687	1.25e-93	ahaA	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
APHAPHFK_02688	1.17e-64	-	-	-	K	ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APHAPHFK_02689	0.0	-	-	-	L	-	-	-	Transposase DDE domain
APHAPHFK_02690	2.66e-210	-	-	-	K	ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APHAPHFK_02691	3.09e-208	-	-	-	G	-	-	-	Fructose-bisphosphate aldolase class-II
APHAPHFK_02692	0.0	-	-	-	G	-	-	-	FGGY family of carbohydrate kinases, C-terminal domain
APHAPHFK_02693	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
APHAPHFK_02694	5.95e-65	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
APHAPHFK_02695	6.52e-103	-	2.7.1.200	-	GT	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APHAPHFK_02696	5.31e-206	-	-	-	G	-	-	-	Fructose-bisphosphate aldolase class-II
APHAPHFK_02697	5.64e-173	farR	-	-	K	-	-	-	Helix-turn-helix domain
APHAPHFK_02698	6.5e-119	-	-	-	K	ko:K03828	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
APHAPHFK_02699	1.3e-146	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
APHAPHFK_02701	1.12e-128	-	-	-	K	-	-	-	Helix-turn-helix domain
APHAPHFK_02702	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
APHAPHFK_02703	1.24e-171	-	-	-	F	-	-	-	NUDIX domain
APHAPHFK_02704	9.35e-140	pncA	-	-	Q	-	-	-	Isochorismatase family
APHAPHFK_02705	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
APHAPHFK_02706	3.71e-171	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
APHAPHFK_02707	5.05e-93	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
APHAPHFK_02708	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
APHAPHFK_02709	6.89e-191	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
APHAPHFK_02710	9.13e-211	-	-	-	P	ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type sugar transport systems, permease components
APHAPHFK_02711	3.22e-269	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
APHAPHFK_02712	9.63e-289	-	-	-	EGP	-	-	-	Transmembrane secretion effector
APHAPHFK_02713	9.1e-191	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
APHAPHFK_02714	7.7e-255	-	-	-	V	-	-	-	Beta-lactamase
APHAPHFK_02715	2.38e-191	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
APHAPHFK_02716	2.83e-212	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
APHAPHFK_02717	6.79e-105	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
APHAPHFK_02718	8.69e-193	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
APHAPHFK_02719	2.1e-183	XK27_08455	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
APHAPHFK_02721	3.7e-260	-	-	-	S	-	-	-	endonuclease exonuclease phosphatase family protein
APHAPHFK_02722	3.94e-221	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
APHAPHFK_02723	1.11e-203	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
APHAPHFK_02724	5.2e-98	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
APHAPHFK_02725	3.57e-186	-	-	-	Q	-	-	-	Methyltransferase
APHAPHFK_02726	1.43e-222	draG	-	-	O	-	-	-	ADP-ribosylglycohydrolase
APHAPHFK_02727	1.25e-67	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
APHAPHFK_02728	1.24e-07	-	-	-	S	-	-	-	SpoVT / AbrB like domain
APHAPHFK_02730	2.38e-80	-	-	-	-	-	-	-	-
APHAPHFK_02731	1.78e-49	-	-	-	-	-	-	-	-
APHAPHFK_02732	2.51e-143	-	-	-	S	-	-	-	alpha beta
APHAPHFK_02733	1.32e-117	yfbM	-	-	K	-	-	-	FR47-like protein
APHAPHFK_02734	1.05e-174	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
APHAPHFK_02735	4.82e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
APHAPHFK_02736	5.06e-160	-	-	-	-	-	-	-	-
APHAPHFK_02737	2.5e-91	-	-	-	S	-	-	-	ASCH
APHAPHFK_02738	1.74e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
APHAPHFK_02739	4.64e-255	ysdE	-	-	P	-	-	-	Citrate transporter
APHAPHFK_02740	1.58e-141	-	-	-	-	-	-	-	-
APHAPHFK_02741	0.0	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
APHAPHFK_02742	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
APHAPHFK_02744	1.34e-219	-	-	-	-	-	-	-	-
APHAPHFK_02745	0.0	cadA	-	-	P	-	-	-	P-type ATPase
APHAPHFK_02746	1.22e-100	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Hsp20/alpha crystallin family
APHAPHFK_02747	2.35e-92	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
APHAPHFK_02748	1.99e-284	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
APHAPHFK_02749	1.15e-15	-	-	-	-	-	-	-	-
APHAPHFK_02750	2.72e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
APHAPHFK_02751	4.46e-184	yycI	-	-	S	-	-	-	YycH protein
APHAPHFK_02752	0.0	yycH	-	-	S	-	-	-	YycH protein
APHAPHFK_02753	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
APHAPHFK_02754	5.24e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
APHAPHFK_02755	6.64e-161	-	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Alpha/beta hydrolase family
APHAPHFK_02756	0.0	arpJ	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
APHAPHFK_02757	1.19e-300	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
APHAPHFK_02758	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
APHAPHFK_02759	3.37e-273	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
APHAPHFK_02760	3.7e-96	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
APHAPHFK_02761	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APHAPHFK_02762	8.04e-168	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
APHAPHFK_02763	9.41e-69	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
APHAPHFK_02764	2.91e-72	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
APHAPHFK_02765	9.03e-141	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
APHAPHFK_02766	1.33e-108	-	-	-	F	-	-	-	NUDIX domain
APHAPHFK_02767	1.7e-117	-	-	-	S	-	-	-	AAA domain
APHAPHFK_02768	2.24e-146	ycaC	-	-	Q	-	-	-	Isochorismatase family
APHAPHFK_02769	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
APHAPHFK_02770	7.39e-274	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
APHAPHFK_02771	6.3e-222	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
APHAPHFK_02772	1.54e-84	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
APHAPHFK_02773	7.33e-218	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
APHAPHFK_02774	6.18e-173	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
APHAPHFK_02775	7.73e-231	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
APHAPHFK_02776	8.76e-282	-	-	-	EGP	-	-	-	Major facilitator Superfamily
APHAPHFK_02777	5.34e-245	-	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
APHAPHFK_02778	4.13e-193	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
APHAPHFK_02779	3.19e-206	-	-	-	K	-	-	-	sequence-specific DNA binding
APHAPHFK_02784	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
APHAPHFK_02785	1.92e-89	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
APHAPHFK_02787	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
APHAPHFK_02788	1.89e-172	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
APHAPHFK_02789	6.51e-54	-	-	-	-	-	-	-	-
APHAPHFK_02790	4.23e-306	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
APHAPHFK_02791	1.39e-169	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
APHAPHFK_02792	7.92e-76	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
APHAPHFK_02793	9.87e-70	-	-	-	-	-	-	-	-
APHAPHFK_02794	4.66e-105	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
APHAPHFK_02795	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
APHAPHFK_02796	9.44e-187	-	-	-	S	-	-	-	AAA ATPase domain
APHAPHFK_02797	3.78e-217	-	-	-	G	-	-	-	Phosphotransferase enzyme family
APHAPHFK_02798	7.69e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
APHAPHFK_02799	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
APHAPHFK_02800	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
APHAPHFK_02801	2.39e-131	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
APHAPHFK_02802	1.06e-135	-	-	-	S	ko:K06384	-	ko00000	Stage II sporulation protein M
APHAPHFK_02803	2.98e-217	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
APHAPHFK_02804	1.26e-210	-	-	-	S	-	-	-	Protein of unknown function DUF58
APHAPHFK_02805	0.0	yebA	-	-	E	-	-	-	Transglutaminase/protease-like homologues
APHAPHFK_02806	3e-273	-	-	-	M	-	-	-	Glycosyl transferases group 1
APHAPHFK_02807	5.98e-114	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
APHAPHFK_02808	2.69e-196	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
APHAPHFK_02809	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
APHAPHFK_02810	3.12e-146	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
APHAPHFK_02811	6.38e-88	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
APHAPHFK_02814	3.26e-162	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
APHAPHFK_02815	9.18e-86	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
APHAPHFK_02816	5.39e-292	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	2-hydroxycarboxylate transporter family
APHAPHFK_02817	0.0	dpiB	2.7.13.3	-	T	ko:K02476,ko:K11614	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Single cache domain 3
APHAPHFK_02818	5.2e-156	malR	-	-	KT	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
APHAPHFK_02819	2.8e-130	-	-	-	-	-	-	-	-
APHAPHFK_02821	3.03e-196	-	-	-	I	-	-	-	NAD binding domain of 6-phosphogluconate dehydrogenase
APHAPHFK_02822	3.93e-90	-	-	-	-	-	-	-	-
APHAPHFK_02823	1.11e-169	-	-	-	F	-	-	-	Glutamine amidotransferase class-I
APHAPHFK_02824	3.35e-217	-	-	-	O	-	-	-	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
APHAPHFK_02825	3.32e-285	sip	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APHAPHFK_02826	8.45e-140	-	-	-	K	ko:K07726	-	ko00000,ko03000	sequence-specific DNA binding
APHAPHFK_02827	1.75e-14	-	-	-	K	ko:K07729	-	ko00000,ko03000	TRANSCRIPTIONal
APHAPHFK_02828	4.94e-58	-	-	-	-	-	-	-	-
APHAPHFK_02829	3.54e-43	-	-	-	-	-	-	-	-
APHAPHFK_02830	3.46e-25	-	-	-	-	-	-	-	-
APHAPHFK_02831	2.82e-40	-	-	-	-	-	-	-	-
APHAPHFK_02832	6.03e-56	-	-	-	-	-	-	-	-
APHAPHFK_02833	1.43e-35	-	-	-	-	-	-	-	-
APHAPHFK_02834	1.07e-205	-	-	-	L	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
APHAPHFK_02835	0.0	-	-	-	S	-	-	-	Virulence-associated protein E
APHAPHFK_02836	3.84e-103	-	-	-	-	-	-	-	-
APHAPHFK_02837	3.53e-99	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	Phage-associated protein
APHAPHFK_02838	8.05e-106	terS	-	-	L	-	-	-	Phage terminase, small subunit
APHAPHFK_02839	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
APHAPHFK_02840	6.27e-31	-	-	-	-	-	-	-	-
APHAPHFK_02841	4.72e-285	-	-	-	S	-	-	-	Phage portal protein
APHAPHFK_02842	0.0	-	-	-	S	ko:K06904	-	ko00000	Phage capsid family
APHAPHFK_02843	2.28e-63	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
APHAPHFK_02844	6.83e-18	-	-	-	S	-	-	-	Phage head-tail joining protein
APHAPHFK_02845	2.3e-23	-	-	-	-	-	-	-	-
APHAPHFK_02846	1.4e-35	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
APHAPHFK_02848	3.77e-217	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
APHAPHFK_02849	2.32e-233	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
APHAPHFK_02850	9.48e-237	lipA	-	-	I	-	-	-	Carboxylesterase family
APHAPHFK_02851	4.29e-276	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
APHAPHFK_02852	5.35e-102	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APHAPHFK_02853	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
APHAPHFK_02854	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
APHAPHFK_02855	1.02e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
APHAPHFK_02856	1.35e-192	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
APHAPHFK_02857	7.2e-60	-	-	-	-	-	-	-	-
APHAPHFK_02858	1.1e-26	-	-	-	-	-	-	-	-
APHAPHFK_02859	9.01e-180	-	-	-	-	-	-	-	-
APHAPHFK_02860	3.21e-287	-	-	-	K	-	-	-	IrrE N-terminal-like domain
APHAPHFK_02861	1.6e-197	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APHAPHFK_02862	2.05e-162	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
APHAPHFK_02863	2.73e-265	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
APHAPHFK_02864	5.68e-242	-	-	-	-	-	-	-	-
APHAPHFK_02865	0.0	-	-	-	M	-	-	-	Leucine rich repeats (6 copies)
APHAPHFK_02866	8.18e-288	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
APHAPHFK_02867	1.34e-187	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
APHAPHFK_02868	5.43e-192	-	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
APHAPHFK_02871	7.4e-254	ypjH	-	-	C	ko:K08317	-	ko00000,ko01000	dehydrogenase
APHAPHFK_02874	2.27e-290	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
APHAPHFK_02875	1.8e-105	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
APHAPHFK_02876	2.57e-173	-	-	-	S	-	-	-	Putative threonine/serine exporter
APHAPHFK_02878	6.86e-43	-	-	-	-	-	-	-	-
APHAPHFK_02879	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
APHAPHFK_02880	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
APHAPHFK_02881	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
APHAPHFK_02882	5.21e-178	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
APHAPHFK_02883	8.28e-182	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
APHAPHFK_02884	1.56e-78	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
APHAPHFK_02886	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
APHAPHFK_02887	0.0	-	-	-	L	-	-	-	PFAM Integrase core domain