ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HGBEPDGP_00001 5.55e-301 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HGBEPDGP_00002 9.88e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HGBEPDGP_00003 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
HGBEPDGP_00004 1.85e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HGBEPDGP_00005 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
HGBEPDGP_00006 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HGBEPDGP_00007 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HGBEPDGP_00008 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HGBEPDGP_00011 2.14e-232 yaaC - - S - - - YaaC-like Protein
HGBEPDGP_00012 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HGBEPDGP_00013 1.03e-315 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HGBEPDGP_00014 1.06e-201 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HGBEPDGP_00015 1.66e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HGBEPDGP_00016 2.3e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HGBEPDGP_00018 3.72e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
HGBEPDGP_00019 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
HGBEPDGP_00020 2.57e-276 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
HGBEPDGP_00021 5.64e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
HGBEPDGP_00022 1.05e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HGBEPDGP_00023 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HGBEPDGP_00024 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HGBEPDGP_00025 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HGBEPDGP_00026 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
HGBEPDGP_00027 6.2e-48 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
HGBEPDGP_00028 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HGBEPDGP_00031 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
HGBEPDGP_00032 3.28e-133 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HGBEPDGP_00033 8.37e-259 yaaN - - P - - - Belongs to the TelA family
HGBEPDGP_00034 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
HGBEPDGP_00035 1.63e-146 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HGBEPDGP_00036 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
HGBEPDGP_00037 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
HGBEPDGP_00038 2.42e-236 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HGBEPDGP_00039 1.1e-189 yaaT - - S - - - stage 0 sporulation protein
HGBEPDGP_00040 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
HGBEPDGP_00041 2.81e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
HGBEPDGP_00042 4.19e-65 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
HGBEPDGP_00043 2.95e-207 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HGBEPDGP_00044 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
HGBEPDGP_00045 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HGBEPDGP_00046 4.85e-183 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
HGBEPDGP_00047 1.18e-277 yabE - - T - - - protein conserved in bacteria
HGBEPDGP_00048 1.43e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HGBEPDGP_00049 5.04e-199 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HGBEPDGP_00050 1.84e-197 yabG - - S ko:K06436 - ko00000 peptidase
HGBEPDGP_00051 5.32e-53 veg - - S - - - protein conserved in bacteria
HGBEPDGP_00052 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
HGBEPDGP_00053 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HGBEPDGP_00054 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
HGBEPDGP_00055 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
HGBEPDGP_00056 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HGBEPDGP_00057 2.58e-309 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HGBEPDGP_00058 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HGBEPDGP_00059 9.8e-135 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HGBEPDGP_00060 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HGBEPDGP_00061 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
HGBEPDGP_00062 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HGBEPDGP_00063 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
HGBEPDGP_00064 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HGBEPDGP_00065 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HGBEPDGP_00066 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HGBEPDGP_00067 1.91e-66 yabP - - S - - - Sporulation protein YabP
HGBEPDGP_00068 2.21e-139 yabQ - - S - - - spore cortex biosynthesis protein
HGBEPDGP_00069 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
HGBEPDGP_00070 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
HGBEPDGP_00073 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
HGBEPDGP_00074 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
HGBEPDGP_00075 1.63e-234 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
HGBEPDGP_00076 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HGBEPDGP_00077 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
HGBEPDGP_00078 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HGBEPDGP_00079 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HGBEPDGP_00080 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HGBEPDGP_00081 2.72e-195 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
HGBEPDGP_00082 1.26e-216 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HGBEPDGP_00083 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HGBEPDGP_00084 1.72e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
HGBEPDGP_00085 1.54e-214 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
HGBEPDGP_00086 1.11e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HGBEPDGP_00087 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HGBEPDGP_00088 9.21e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HGBEPDGP_00089 1.81e-41 yazB - - K - - - transcriptional
HGBEPDGP_00090 1.59e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HGBEPDGP_00091 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HGBEPDGP_00092 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HGBEPDGP_00102 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HGBEPDGP_00103 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
HGBEPDGP_00104 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
HGBEPDGP_00105 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HGBEPDGP_00106 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
HGBEPDGP_00107 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HGBEPDGP_00108 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HGBEPDGP_00109 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
HGBEPDGP_00110 4.29e-161 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HGBEPDGP_00111 2.59e-112 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HGBEPDGP_00112 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HGBEPDGP_00113 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
HGBEPDGP_00114 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HGBEPDGP_00115 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HGBEPDGP_00116 3.52e-173 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HGBEPDGP_00117 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
HGBEPDGP_00118 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
HGBEPDGP_00119 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HGBEPDGP_00120 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HGBEPDGP_00121 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HGBEPDGP_00122 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HGBEPDGP_00123 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HGBEPDGP_00124 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HGBEPDGP_00125 5.1e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
HGBEPDGP_00126 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGBEPDGP_00127 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGBEPDGP_00128 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
HGBEPDGP_00129 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HGBEPDGP_00130 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HGBEPDGP_00131 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HGBEPDGP_00132 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HGBEPDGP_00133 8.68e-229 ybaC - - S - - - Alpha/beta hydrolase family
HGBEPDGP_00134 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HGBEPDGP_00135 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HGBEPDGP_00136 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HGBEPDGP_00137 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HGBEPDGP_00138 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HGBEPDGP_00139 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HGBEPDGP_00140 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HGBEPDGP_00141 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HGBEPDGP_00142 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HGBEPDGP_00143 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HGBEPDGP_00144 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HGBEPDGP_00145 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HGBEPDGP_00146 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HGBEPDGP_00147 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HGBEPDGP_00148 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HGBEPDGP_00149 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HGBEPDGP_00150 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HGBEPDGP_00151 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HGBEPDGP_00152 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HGBEPDGP_00153 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
HGBEPDGP_00154 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
HGBEPDGP_00155 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HGBEPDGP_00156 1.46e-156 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HGBEPDGP_00157 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
HGBEPDGP_00158 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HGBEPDGP_00159 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
HGBEPDGP_00160 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HGBEPDGP_00161 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HGBEPDGP_00162 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGBEPDGP_00163 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HGBEPDGP_00164 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HGBEPDGP_00165 1.28e-195 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HGBEPDGP_00166 1.6e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HGBEPDGP_00167 1.51e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HGBEPDGP_00168 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HGBEPDGP_00169 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HGBEPDGP_00170 2.14e-186 ybaJ - - Q - - - Methyltransferase domain
HGBEPDGP_00171 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
HGBEPDGP_00172 2.22e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
HGBEPDGP_00173 4.47e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HGBEPDGP_00174 1.04e-122 gerD - - - ko:K06294 - ko00000 -
HGBEPDGP_00175 2.42e-132 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
HGBEPDGP_00176 2.49e-180 pdaB - - G - - - Polysaccharide deacetylase
HGBEPDGP_00177 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HGBEPDGP_00184 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HGBEPDGP_00185 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HGBEPDGP_00186 2.61e-316 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
HGBEPDGP_00188 1.26e-201 ybaS - - S - - - Na -dependent transporter
HGBEPDGP_00189 5.87e-177 ybbA - - S ko:K07017 - ko00000 Putative esterase
HGBEPDGP_00190 2.37e-226 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGBEPDGP_00191 1.17e-225 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGBEPDGP_00192 1.26e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
HGBEPDGP_00193 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
HGBEPDGP_00194 8.14e-303 ybbC - - S - - - protein conserved in bacteria
HGBEPDGP_00195 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
HGBEPDGP_00196 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
HGBEPDGP_00197 1.04e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HGBEPDGP_00198 3.01e-191 ybbH - - K - - - transcriptional
HGBEPDGP_00199 1.11e-208 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HGBEPDGP_00200 1.81e-113 ybbJ - - J - - - acetyltransferase
HGBEPDGP_00201 4.19e-101 ybbK - - S - - - Protein of unknown function (DUF523)
HGBEPDGP_00207 9.27e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HGBEPDGP_00208 3.19e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HGBEPDGP_00209 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HGBEPDGP_00210 3.41e-291 ybbR - - S - - - protein conserved in bacteria
HGBEPDGP_00211 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HGBEPDGP_00212 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HGBEPDGP_00213 5.38e-220 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HGBEPDGP_00214 1.03e-153 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
HGBEPDGP_00215 1.06e-128 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HGBEPDGP_00216 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HGBEPDGP_00217 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
HGBEPDGP_00218 1.99e-120 ybcF - - P - - - carbonic anhydrase
HGBEPDGP_00219 3.12e-61 - - - - - - - -
HGBEPDGP_00220 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
HGBEPDGP_00221 9.45e-67 - - - K - - - Helix-turn-helix domain
HGBEPDGP_00222 1.81e-255 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
HGBEPDGP_00224 1.21e-21 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HGBEPDGP_00225 7.04e-139 bsaB - - S ko:K20483 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lantibiotic dehydratase, C terminus
HGBEPDGP_00226 6.48e-50 spaC1 - - V ko:K20484 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lanthionine synthetase C family protein
HGBEPDGP_00228 6.47e-176 abcA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
HGBEPDGP_00229 2.31e-232 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HGBEPDGP_00230 1.39e-157 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
HGBEPDGP_00231 4.22e-214 - - - T - - - His Kinase A (phospho-acceptor) domain
HGBEPDGP_00233 8.34e-180 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
HGBEPDGP_00234 7.4e-193 ybdN - - - - - - -
HGBEPDGP_00235 1.22e-271 ybdO - - S - - - Domain of unknown function (DUF4885)
HGBEPDGP_00236 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HGBEPDGP_00237 5.46e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
HGBEPDGP_00238 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
HGBEPDGP_00239 1.06e-192 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
HGBEPDGP_00240 8.23e-309 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
HGBEPDGP_00241 1.11e-54 ybyB - - - - - - -
HGBEPDGP_00242 0.0 ybeC - - E - - - amino acid
HGBEPDGP_00243 7.3e-213 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
HGBEPDGP_00244 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
HGBEPDGP_00245 3.57e-47 - - - S - - - Protein of unknown function (DUF2651)
HGBEPDGP_00246 2.1e-218 ybfA - - K - - - FR47-like protein
HGBEPDGP_00247 2.75e-286 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
HGBEPDGP_00249 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
HGBEPDGP_00250 5.27e-208 ybfH - - EG - - - EamA-like transporter family
HGBEPDGP_00251 7.39e-188 ybfI - - K - - - AraC-like ligand binding domain
HGBEPDGP_00252 2.78e-272 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HGBEPDGP_00253 1.97e-227 mpr - - M - - - Belongs to the peptidase S1B family
HGBEPDGP_00255 4.38e-211 - - - S - - - Alpha/beta hydrolase family
HGBEPDGP_00256 6.9e-124 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HGBEPDGP_00257 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
HGBEPDGP_00258 1.45e-188 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HGBEPDGP_00259 1.58e-59 ybfN - - - - - - -
HGBEPDGP_00260 2.35e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
HGBEPDGP_00261 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HGBEPDGP_00262 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HGBEPDGP_00263 1.23e-173 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HGBEPDGP_00264 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
HGBEPDGP_00266 8.08e-260 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HGBEPDGP_00267 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HGBEPDGP_00268 9.76e-229 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
HGBEPDGP_00269 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
HGBEPDGP_00270 9.16e-240 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HGBEPDGP_00271 3.55e-294 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HGBEPDGP_00272 1.72e-217 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
HGBEPDGP_00273 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
HGBEPDGP_00274 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HGBEPDGP_00275 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HGBEPDGP_00276 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
HGBEPDGP_00277 4.63e-161 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
HGBEPDGP_00278 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
HGBEPDGP_00279 2.47e-222 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
HGBEPDGP_00280 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
HGBEPDGP_00281 7.31e-218 eamA1 - - EG - - - spore germination
HGBEPDGP_00282 3.71e-160 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGBEPDGP_00283 6.21e-214 ycbM - - T - - - Histidine kinase
HGBEPDGP_00284 1.66e-216 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HGBEPDGP_00285 2.87e-148 - - - S - - - ABC-2 family transporter protein
HGBEPDGP_00286 1.82e-75 ycbP - - S - - - Protein of unknown function (DUF2512)
HGBEPDGP_00287 1.82e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
HGBEPDGP_00288 5.44e-174 ycbR - - T - - - vWA found in TerF C terminus
HGBEPDGP_00289 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
HGBEPDGP_00290 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HGBEPDGP_00291 3.09e-159 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HGBEPDGP_00292 9.85e-154 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HGBEPDGP_00293 4.86e-259 ycbU - - E - - - Selenocysteine lyase
HGBEPDGP_00294 2.51e-302 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
HGBEPDGP_00295 1.88e-131 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
HGBEPDGP_00296 1.97e-256 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HGBEPDGP_00297 1.63e-146 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
HGBEPDGP_00298 4.32e-78 - - - S - - - RDD family
HGBEPDGP_00299 1.01e-254 yccF - - K ko:K07039 - ko00000 SEC-C motif
HGBEPDGP_00300 1.77e-212 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HGBEPDGP_00301 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HGBEPDGP_00302 2.2e-170 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HGBEPDGP_00303 5.64e-257 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HGBEPDGP_00304 6.81e-222 yccK - - C - - - Aldo keto reductase
HGBEPDGP_00305 1.35e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
HGBEPDGP_00306 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HGBEPDGP_00307 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HGBEPDGP_00308 2.65e-123 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
HGBEPDGP_00309 2.86e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
HGBEPDGP_00310 1.96e-179 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
HGBEPDGP_00311 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
HGBEPDGP_00312 1.95e-221 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HGBEPDGP_00313 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HGBEPDGP_00314 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HGBEPDGP_00315 4.01e-236 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGBEPDGP_00316 1.78e-139 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
HGBEPDGP_00317 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
HGBEPDGP_00318 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
HGBEPDGP_00319 1.18e-175 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
HGBEPDGP_00320 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
HGBEPDGP_00321 2.96e-245 yceH - - P - - - Belongs to the TelA family
HGBEPDGP_00322 2.32e-279 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
HGBEPDGP_00323 2.25e-265 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
HGBEPDGP_00324 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HGBEPDGP_00325 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
HGBEPDGP_00326 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
HGBEPDGP_00327 2.01e-210 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
HGBEPDGP_00328 1.97e-276 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
HGBEPDGP_00329 0.0 ycgA - - S - - - Membrane
HGBEPDGP_00330 2.72e-105 ycgB - - - - - - -
HGBEPDGP_00331 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
HGBEPDGP_00332 2.06e-233 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HGBEPDGP_00333 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HGBEPDGP_00334 0.0 mdr - - EGP - - - the major facilitator superfamily
HGBEPDGP_00335 3.7e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
HGBEPDGP_00336 6.42e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
HGBEPDGP_00337 2.07e-192 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
HGBEPDGP_00338 0.0 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HGBEPDGP_00339 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
HGBEPDGP_00340 1.83e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HGBEPDGP_00341 3.09e-139 tmrB - - S - - - AAA domain
HGBEPDGP_00343 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HGBEPDGP_00344 7.18e-184 - - - Q - - - ubiE/COQ5 methyltransferase family
HGBEPDGP_00345 1.88e-226 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
HGBEPDGP_00346 1.1e-231 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
HGBEPDGP_00347 3.69e-185 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
HGBEPDGP_00348 2.1e-217 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
HGBEPDGP_00349 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
HGBEPDGP_00350 1.05e-315 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HGBEPDGP_00351 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
HGBEPDGP_00352 1.28e-193 ycgQ - - S ko:K08986 - ko00000 membrane
HGBEPDGP_00353 2.41e-184 ycgR - - S ko:K07089 - ko00000 permeases
HGBEPDGP_00354 3.44e-202 ycgS - - I - - - alpha/beta hydrolase fold
HGBEPDGP_00355 8.53e-245 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
HGBEPDGP_00356 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
HGBEPDGP_00357 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
HGBEPDGP_00358 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HGBEPDGP_00359 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HGBEPDGP_00360 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
HGBEPDGP_00361 6.43e-282 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
HGBEPDGP_00362 1.22e-221 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
HGBEPDGP_00363 1.73e-139 - - - M - - - ErfK YbiS YcfS YnhG
HGBEPDGP_00364 6.78e-291 yciC - - S - - - GTPases (G3E family)
HGBEPDGP_00365 2.99e-149 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HGBEPDGP_00366 3.76e-187 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HGBEPDGP_00368 5.95e-101 yckC - - S - - - membrane
HGBEPDGP_00369 3.53e-69 yckD - - S - - - Protein of unknown function (DUF2680)
HGBEPDGP_00370 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HGBEPDGP_00371 4.78e-91 nin - - S - - - Competence protein J (ComJ)
HGBEPDGP_00372 3.23e-99 nucA - - M - - - Deoxyribonuclease NucA/NucB
HGBEPDGP_00373 1.86e-268 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HGBEPDGP_00374 1.13e-126 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
HGBEPDGP_00375 5.63e-137 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
HGBEPDGP_00376 6.05e-86 hxlR - - K - - - transcriptional
HGBEPDGP_00377 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGBEPDGP_00378 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGBEPDGP_00379 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
HGBEPDGP_00380 2.71e-178 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
HGBEPDGP_00381 6.53e-290 - - - EGP - - - Major Facilitator Superfamily
HGBEPDGP_00382 2.87e-120 - - - S - - - YcxB-like protein
HGBEPDGP_00383 7.69e-204 ycxC - - EG - - - EamA-like transporter family
HGBEPDGP_00384 2.69e-201 ycxD - - K - - - GntR family transcriptional regulator
HGBEPDGP_00385 1.33e-100 ycxD - - K - - - GntR family transcriptional regulator
HGBEPDGP_00386 2.02e-146 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
HGBEPDGP_00387 8.71e-148 yczE - - S ko:K07149 - ko00000 membrane
HGBEPDGP_00388 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HGBEPDGP_00389 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HGBEPDGP_00390 1.23e-187 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HGBEPDGP_00391 5.32e-209 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
HGBEPDGP_00392 2.24e-140 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HGBEPDGP_00393 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HGBEPDGP_00394 9.86e-53 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
HGBEPDGP_00395 2.82e-105 yclD - - - - - - -
HGBEPDGP_00396 2.15e-199 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
HGBEPDGP_00397 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
HGBEPDGP_00398 0.0 yclG - - M - - - Pectate lyase superfamily protein
HGBEPDGP_00400 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
HGBEPDGP_00401 8.35e-297 gerKC - - S ko:K06297 - ko00000 spore germination
HGBEPDGP_00402 2.29e-254 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
HGBEPDGP_00403 2.39e-155 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HGBEPDGP_00404 2.59e-274 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
HGBEPDGP_00405 1.51e-163 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGBEPDGP_00406 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HGBEPDGP_00407 2.18e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HGBEPDGP_00410 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HGBEPDGP_00411 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGBEPDGP_00412 7.77e-210 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGBEPDGP_00413 1.61e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HGBEPDGP_00414 3.09e-217 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
HGBEPDGP_00415 0.0 ycnB - - EGP - - - the major facilitator superfamily
HGBEPDGP_00416 5.87e-198 ycnC - - K - - - Transcriptional regulator
HGBEPDGP_00417 2.12e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
HGBEPDGP_00418 1.68e-60 ycnE - - S - - - Monooxygenase
HGBEPDGP_00419 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HGBEPDGP_00420 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HGBEPDGP_00421 4.64e-311 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HGBEPDGP_00422 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HGBEPDGP_00423 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
HGBEPDGP_00424 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGBEPDGP_00425 3.99e-134 ycnI - - S - - - protein conserved in bacteria
HGBEPDGP_00426 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
HGBEPDGP_00427 1.22e-137 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HGBEPDGP_00428 1.34e-74 - - - - - - - -
HGBEPDGP_00429 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
HGBEPDGP_00430 8.3e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HGBEPDGP_00431 2.97e-266 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
HGBEPDGP_00432 1.68e-255 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
HGBEPDGP_00434 1.78e-96 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HGBEPDGP_00435 1.71e-143 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
HGBEPDGP_00436 1.89e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
HGBEPDGP_00438 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
HGBEPDGP_00439 3.82e-181 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
HGBEPDGP_00440 1.87e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
HGBEPDGP_00441 7e-190 ycsI - - S - - - Belongs to the D-glutamate cyclase family
HGBEPDGP_00442 9.77e-171 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
HGBEPDGP_00443 1.99e-238 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
HGBEPDGP_00444 1.55e-170 kipR - - K - - - Transcriptional regulator
HGBEPDGP_00445 5.94e-154 ycsK - - E - - - anatomical structure formation involved in morphogenesis
HGBEPDGP_00447 8.97e-65 yczJ - - S - - - biosynthesis
HGBEPDGP_00448 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
HGBEPDGP_00449 2.54e-58 ycsN - - S - - - Oxidoreductase
HGBEPDGP_00450 7.37e-129 ycsN - - S - - - Oxidoreductase
HGBEPDGP_00451 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
HGBEPDGP_00452 0.0 ydaB - - IQ - - - acyl-CoA ligase
HGBEPDGP_00453 1e-127 ydaC - - Q - - - Methyltransferase domain
HGBEPDGP_00454 1.07e-206 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGBEPDGP_00455 2.75e-125 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
HGBEPDGP_00456 2.69e-133 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HGBEPDGP_00457 5.24e-101 ydaG - - S - - - general stress protein
HGBEPDGP_00458 5.35e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HGBEPDGP_00459 3.12e-61 ydzA - - EGP - - - Domain of unknown function (DUF3817)
HGBEPDGP_00460 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
HGBEPDGP_00461 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HGBEPDGP_00462 1.11e-260 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
HGBEPDGP_00463 5.21e-192 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
HGBEPDGP_00464 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
HGBEPDGP_00465 7.86e-304 ydaM - - M - - - Glycosyl transferase family group 2
HGBEPDGP_00466 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
HGBEPDGP_00467 0.0 ydaO - - E - - - amino acid
HGBEPDGP_00468 3.08e-102 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
HGBEPDGP_00469 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HGBEPDGP_00470 2.14e-53 - - - - - - - -
HGBEPDGP_00471 7.87e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HGBEPDGP_00472 1.67e-42 ydaS - - S - - - membrane
HGBEPDGP_00473 2.25e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
HGBEPDGP_00474 1.75e-189 ydbA - - P - - - EcsC protein family
HGBEPDGP_00475 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
HGBEPDGP_00476 7.58e-79 ydbB - - G - - - Cupin domain
HGBEPDGP_00477 4.45e-83 ydbC - - S - - - Domain of unknown function (DUF4937
HGBEPDGP_00478 1.06e-195 ydbD - - P ko:K07217 - ko00000 Catalase
HGBEPDGP_00479 1.43e-250 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HGBEPDGP_00480 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HGBEPDGP_00481 1.38e-154 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
HGBEPDGP_00482 8.93e-290 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HGBEPDGP_00483 1.32e-230 ydbI - - S - - - AI-2E family transporter
HGBEPDGP_00484 3.23e-219 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HGBEPDGP_00485 2.99e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HGBEPDGP_00486 7.67e-69 ydbL - - - - - - -
HGBEPDGP_00487 7.45e-280 ydbM - - I - - - acyl-CoA dehydrogenase
HGBEPDGP_00488 1.49e-26 - - - S - - - Fur-regulated basic protein B
HGBEPDGP_00490 1.35e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HGBEPDGP_00491 4.19e-75 ydbP - - CO - - - Thioredoxin
HGBEPDGP_00492 3.58e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HGBEPDGP_00493 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HGBEPDGP_00494 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HGBEPDGP_00495 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
HGBEPDGP_00496 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
HGBEPDGP_00497 2.53e-139 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
HGBEPDGP_00498 1.6e-77 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HGBEPDGP_00499 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
HGBEPDGP_00500 5.29e-284 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HGBEPDGP_00501 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HGBEPDGP_00502 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HGBEPDGP_00503 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
HGBEPDGP_00504 7.34e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
HGBEPDGP_00505 8.56e-90 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HGBEPDGP_00506 1.31e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
HGBEPDGP_00507 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
HGBEPDGP_00508 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HGBEPDGP_00509 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGBEPDGP_00510 1.86e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
HGBEPDGP_00514 1.32e-106 ydcG - - S - - - EVE domain
HGBEPDGP_00515 1.54e-101 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HGBEPDGP_00516 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
HGBEPDGP_00517 1.53e-107 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
HGBEPDGP_00525 7.32e-92 - - - J - - - Acetyltransferase (GNAT) domain
HGBEPDGP_00526 2.85e-58 - - - - - - - -
HGBEPDGP_00527 3.85e-24 - - - S ko:K21493 - ko00000,ko01000,ko02048 LXG domain of WXG superfamily
HGBEPDGP_00528 8.43e-29 - - - L ko:K07451,ko:K07452 - ko00000,ko01000,ko02048 HNH endonuclease
HGBEPDGP_00529 9.05e-56 - - - L - - - HNH nucleases
HGBEPDGP_00532 7.24e-08 - - - S - - - Putative amidase domain
HGBEPDGP_00535 1.8e-45 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
HGBEPDGP_00536 1.72e-52 - - - - - - - -
HGBEPDGP_00540 4.24e-146 ydeA - - S - - - DJ-1/PfpI family
HGBEPDGP_00541 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
HGBEPDGP_00542 5.92e-102 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
HGBEPDGP_00543 3.56e-184 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HGBEPDGP_00544 2.18e-213 - - - K - - - AraC-like ligand binding domain
HGBEPDGP_00545 2.37e-222 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HGBEPDGP_00546 4.06e-209 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
HGBEPDGP_00547 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HGBEPDGP_00548 5.15e-275 ydeG - - EGP - - - Major facilitator superfamily
HGBEPDGP_00549 9.2e-70 ydeH - - - - - - -
HGBEPDGP_00550 6.99e-136 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
HGBEPDGP_00551 2.46e-140 - - - - - - - -
HGBEPDGP_00552 2.79e-100 - - - I - - - Ribosomal RNA adenine dimethylase
HGBEPDGP_00553 5.54e-146 - - - T - - - Transcriptional regulator
HGBEPDGP_00554 2.65e-176 - - - T - - - COG0642 Signal transduction histidine kinase
HGBEPDGP_00555 4.01e-92 - - - S - - - SNARE associated Golgi protein
HGBEPDGP_00556 3.3e-19 ptsH - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
HGBEPDGP_00557 1.72e-110 - - - K - - - Transcriptional regulator C-terminal region
HGBEPDGP_00559 6.08e-193 ydeK - - EG - - - -transporter
HGBEPDGP_00560 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HGBEPDGP_00561 2.49e-95 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
HGBEPDGP_00562 2.31e-133 - - - S ko:K07002 - ko00000 Serine hydrolase
HGBEPDGP_00563 8.68e-74 - - - K - - - HxlR-like helix-turn-helix
HGBEPDGP_00564 1.32e-193 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HGBEPDGP_00565 2.92e-90 ydeP - - K - - - Transcriptional regulator
HGBEPDGP_00566 2.36e-143 ywrO - - S ko:K11748 - ko00000,ko02000 NADPH-quinone reductase (modulator of drug activity B)
HGBEPDGP_00567 1.13e-256 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
HGBEPDGP_00568 4.73e-133 ydeS - - K - - - Transcriptional regulator
HGBEPDGP_00569 1.05e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
HGBEPDGP_00570 3.53e-294 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HGBEPDGP_00571 8.77e-145 - - - J - - - GNAT acetyltransferase
HGBEPDGP_00572 9.56e-195 - - - EG - - - EamA-like transporter family
HGBEPDGP_00573 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HGBEPDGP_00574 2.34e-148 ydfE - - S - - - Flavin reductase like domain
HGBEPDGP_00575 5.24e-159 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HGBEPDGP_00576 1.12e-103 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HGBEPDGP_00578 7.24e-247 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HGBEPDGP_00579 2.3e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGBEPDGP_00580 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
HGBEPDGP_00581 7.67e-223 - - - S - - - Alpha/beta hydrolase family
HGBEPDGP_00582 7.6e-149 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HGBEPDGP_00583 1.23e-188 - - - K - - - Bacterial transcription activator, effector binding domain
HGBEPDGP_00584 2.12e-198 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HGBEPDGP_00585 7.8e-142 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
HGBEPDGP_00586 1.51e-235 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HGBEPDGP_00587 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
HGBEPDGP_00588 7.63e-74 ydfQ - - CO - - - Thioredoxin
HGBEPDGP_00589 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
HGBEPDGP_00590 5.33e-39 - - - - - - - -
HGBEPDGP_00592 6.08e-153 ydfR - - S - - - Protein of unknown function (DUF421)
HGBEPDGP_00593 2.57e-159 ydfS - - S - - - Protein of unknown function (DUF421)
HGBEPDGP_00594 3.13e-99 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HGBEPDGP_00595 2.74e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
HGBEPDGP_00596 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
HGBEPDGP_00597 4.04e-126 ydgC - - K - - - Bacterial regulatory proteins, tetR family
HGBEPDGP_00598 1.93e-68 - - - S - - - DoxX-like family
HGBEPDGP_00599 2.46e-68 yycN - - K - - - Acetyltransferase
HGBEPDGP_00600 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
HGBEPDGP_00601 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
HGBEPDGP_00602 2.32e-115 - - - S - - - DinB family
HGBEPDGP_00603 8.04e-102 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HGBEPDGP_00604 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
HGBEPDGP_00605 9.12e-147 ydgI - - C - - - nitroreductase
HGBEPDGP_00606 6.63e-90 - - - K - - - Winged helix DNA-binding domain
HGBEPDGP_00607 4.02e-265 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
HGBEPDGP_00608 1.02e-154 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
HGBEPDGP_00609 4.31e-157 ydhC - - K - - - FCD
HGBEPDGP_00610 7.33e-309 ydhD - - M - - - Glycosyl hydrolase
HGBEPDGP_00611 7.9e-289 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HGBEPDGP_00612 4.79e-160 - - - - - - - -
HGBEPDGP_00613 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
HGBEPDGP_00614 2.74e-88 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
HGBEPDGP_00616 2.2e-107 - - - K - - - Acetyltransferase (GNAT) domain
HGBEPDGP_00617 9.03e-230 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HGBEPDGP_00618 7.76e-128 ydhK - - M - - - Protein of unknown function (DUF1541)
HGBEPDGP_00619 8.95e-255 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
HGBEPDGP_00620 1.88e-63 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HGBEPDGP_00621 3.39e-67 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HGBEPDGP_00622 6.51e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HGBEPDGP_00623 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HGBEPDGP_00624 1.83e-169 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
HGBEPDGP_00625 4.94e-214 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
HGBEPDGP_00626 8.45e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HGBEPDGP_00627 6.49e-269 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
HGBEPDGP_00628 4.89e-202 ydhU - - P ko:K07217 - ko00000 Catalase
HGBEPDGP_00631 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HGBEPDGP_00634 1.9e-231 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HGBEPDGP_00635 7.42e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
HGBEPDGP_00636 1.76e-163 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
HGBEPDGP_00637 2.34e-107 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HGBEPDGP_00638 5.46e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HGBEPDGP_00639 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
HGBEPDGP_00640 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HGBEPDGP_00641 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HGBEPDGP_00642 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HGBEPDGP_00643 8.73e-162 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HGBEPDGP_00644 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
HGBEPDGP_00645 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
HGBEPDGP_00646 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HGBEPDGP_00647 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HGBEPDGP_00648 7.76e-182 - - - L - - - Belongs to the 'phage' integrase family
HGBEPDGP_00649 1.17e-62 xkdA - - E - - - IrrE N-terminal-like domain
HGBEPDGP_00650 1.75e-13 - - - S - - - Short C-terminal domain
HGBEPDGP_00651 2.76e-59 - - - K - - - Helix-turn-helix XRE-family like proteins
HGBEPDGP_00652 1.15e-26 - - - K - - - Helix-turn-helix XRE-family like proteins
HGBEPDGP_00653 9.71e-48 - - - - - - - -
HGBEPDGP_00654 2.62e-50 - - - S - - - DNA binding
HGBEPDGP_00655 1.89e-88 - - - - - - - -
HGBEPDGP_00660 3.94e-123 - - - - - - - -
HGBEPDGP_00661 3.34e-90 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
HGBEPDGP_00662 2.06e-61 yqaL - - L - - - DnaD domain protein
HGBEPDGP_00663 4.27e-102 yqaM - - L - - - IstB-like ATP binding protein
HGBEPDGP_00665 6.24e-95 - - - - - - - -
HGBEPDGP_00666 2.59e-70 - - - S - - - Protein of unknown function (DUF1064)
HGBEPDGP_00668 1.85e-29 yqaO - - S - - - Phage-like element PBSX protein XtrA
HGBEPDGP_00670 8.96e-98 - - - - - - - -
HGBEPDGP_00683 2.15e-104 - - - L - - - Transposase
HGBEPDGP_00685 3.59e-32 - - - - - - - -
HGBEPDGP_00686 1.69e-113 yqaS - - L - - - DNA packaging
HGBEPDGP_00687 8.44e-230 - - - S - - - Terminase-like family
HGBEPDGP_00688 2.72e-148 - - - S - - - Phage portal protein, SPP1 Gp6-like
HGBEPDGP_00689 3.62e-110 - - - S - - - Phage Mu protein F like protein
HGBEPDGP_00692 3.09e-55 - - - S - - - Phage minor structural protein GP20
HGBEPDGP_00693 4.89e-61 - - - S - - - viral capsid
HGBEPDGP_00695 3.39e-35 - - - S - - - Phage gp6-like head-tail connector protein
HGBEPDGP_00696 5.61e-38 - - - S - - - Phage head-tail joining protein
HGBEPDGP_00697 5.76e-46 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
HGBEPDGP_00698 4.91e-39 - - - S - - - Protein of unknown function (DUF3168)
HGBEPDGP_00699 1.14e-44 - - - S - - - Phage tail tube protein
HGBEPDGP_00700 1.04e-36 - - - S - - - Phage tail assembly chaperone protein, TAC
HGBEPDGP_00701 1.04e-170 - - - - - - - -
HGBEPDGP_00702 4.34e-12 - - - S - - - phage tail component
HGBEPDGP_00703 3.96e-272 - - - S - - - peptidoglycan catabolic process
HGBEPDGP_00708 1.95e-37 xhlA - - S - - - Haemolysin XhlA
HGBEPDGP_00709 1.58e-41 xhlB - - S - - - SPP1 phage holin
HGBEPDGP_00710 2.77e-136 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
HGBEPDGP_00714 4.58e-36 - - - K - - - Helix-turn-helix domain
HGBEPDGP_00716 2.85e-113 - - - E - - - Zn peptidase
HGBEPDGP_00720 1.93e-53 - - - - - - - -
HGBEPDGP_00721 7.05e-293 - - - S - - - Bacterial EndoU nuclease
HGBEPDGP_00724 4.31e-82 yozB - - S ko:K08976 - ko00000 Membrane
HGBEPDGP_00725 8.95e-31 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
HGBEPDGP_00726 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
HGBEPDGP_00727 4.32e-258 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
HGBEPDGP_00728 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
HGBEPDGP_00729 7.03e-220 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
HGBEPDGP_00730 1.6e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
HGBEPDGP_00731 1.04e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HGBEPDGP_00732 3.96e-177 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
HGBEPDGP_00733 3.61e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
HGBEPDGP_00734 2.18e-245 - - - S - - - Ion transport 2 domain protein
HGBEPDGP_00735 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HGBEPDGP_00736 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
HGBEPDGP_00737 1.79e-84 ydjM - - M - - - Lytic transglycolase
HGBEPDGP_00738 4.44e-205 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
HGBEPDGP_00740 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
HGBEPDGP_00741 1.25e-202 - - - I - - - Alpha/beta hydrolase family
HGBEPDGP_00742 1.96e-226 yeaA - - S - - - Protein of unknown function (DUF4003)
HGBEPDGP_00743 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
HGBEPDGP_00744 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
HGBEPDGP_00745 1.44e-197 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HGBEPDGP_00746 2.79e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
HGBEPDGP_00747 1.59e-285 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HGBEPDGP_00748 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
HGBEPDGP_00749 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HGBEPDGP_00750 3.99e-282 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HGBEPDGP_00751 1.95e-163 yebC - - M - - - Membrane
HGBEPDGP_00753 5.36e-120 yebE - - S - - - UPF0316 protein
HGBEPDGP_00754 3.13e-38 yebG - - S - - - NETI protein
HGBEPDGP_00755 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HGBEPDGP_00756 2.91e-275 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HGBEPDGP_00757 8.03e-314 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HGBEPDGP_00758 2.04e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HGBEPDGP_00759 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HGBEPDGP_00760 4.69e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HGBEPDGP_00761 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HGBEPDGP_00762 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HGBEPDGP_00763 1.71e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HGBEPDGP_00764 8.88e-138 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HGBEPDGP_00765 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HGBEPDGP_00766 5.69e-298 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HGBEPDGP_00767 1.29e-94 - - - K - - - helix_turn_helix ASNC type
HGBEPDGP_00768 4.8e-291 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
HGBEPDGP_00769 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
HGBEPDGP_00770 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
HGBEPDGP_00771 9.18e-242 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
HGBEPDGP_00772 7.62e-68 yerC - - S - - - protein conserved in bacteria
HGBEPDGP_00773 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
HGBEPDGP_00775 7.43e-160 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HGBEPDGP_00776 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HGBEPDGP_00777 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HGBEPDGP_00778 1.77e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
HGBEPDGP_00779 1.73e-250 yerI - - S - - - homoserine kinase type II (protein kinase fold)
HGBEPDGP_00780 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
HGBEPDGP_00781 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HGBEPDGP_00782 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HGBEPDGP_00783 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HGBEPDGP_00784 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HGBEPDGP_00785 2.43e-189 yerO - - K - - - Transcriptional regulator
HGBEPDGP_00786 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HGBEPDGP_00787 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HGBEPDGP_00788 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HGBEPDGP_00789 0.0 - 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system methyltransferase subunit()
HGBEPDGP_00790 6.7e-95 - - - V - - - Type I restriction modification DNA specificity domain
HGBEPDGP_00793 3.95e-125 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HGBEPDGP_00795 4.5e-41 - - - S - - - Colicin immunity protein / pyocin immunity protein
HGBEPDGP_00797 8.48e-105 - - - S - - - Protein of unknown function, DUF600
HGBEPDGP_00798 1.09e-73 - - - S - - - Protein of unknown function, DUF600
HGBEPDGP_00799 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
HGBEPDGP_00800 2.32e-235 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
HGBEPDGP_00801 1.42e-270 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
HGBEPDGP_00803 1.09e-162 yeeN - - K - - - transcriptional regulatory protein
HGBEPDGP_00805 2.85e-129 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
HGBEPDGP_00806 2.02e-106 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
HGBEPDGP_00807 1.23e-195 yesF - - GM - - - NAD(P)H-binding
HGBEPDGP_00808 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
HGBEPDGP_00809 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
HGBEPDGP_00810 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
HGBEPDGP_00811 2.4e-130 yesJ - - K - - - Acetyltransferase (GNAT) family
HGBEPDGP_00812 1.95e-132 yesL - - S - - - Protein of unknown function, DUF624
HGBEPDGP_00813 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HGBEPDGP_00814 2.31e-256 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
HGBEPDGP_00815 1.44e-314 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HGBEPDGP_00816 2.02e-218 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGBEPDGP_00817 5.11e-210 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGBEPDGP_00818 5.63e-254 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
HGBEPDGP_00819 0.0 yesS - - K - - - Transcriptional regulator
HGBEPDGP_00820 9.8e-169 - - - E - - - GDSL-like Lipase/Acylhydrolase
HGBEPDGP_00821 7.22e-163 yesU - - S - - - Domain of unknown function (DUF1961)
HGBEPDGP_00822 7.78e-143 - - - S - - - Protein of unknown function, DUF624
HGBEPDGP_00823 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
HGBEPDGP_00824 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
HGBEPDGP_00825 7.51e-159 - - - E - - - GDSL-like Lipase/Acylhydrolase
HGBEPDGP_00826 1.6e-47 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
HGBEPDGP_00827 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
HGBEPDGP_00828 0.0 yetA - - - - - - -
HGBEPDGP_00829 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HGBEPDGP_00830 6.84e-226 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
HGBEPDGP_00831 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGBEPDGP_00832 1.66e-292 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
HGBEPDGP_00833 6.06e-156 yetF - - S - - - membrane
HGBEPDGP_00834 1.57e-71 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
HGBEPDGP_00835 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGBEPDGP_00836 9.79e-45 - - - - - - - -
HGBEPDGP_00837 3.08e-185 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HGBEPDGP_00838 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
HGBEPDGP_00839 2.1e-134 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
HGBEPDGP_00840 2.75e-116 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
HGBEPDGP_00841 1.78e-265 yetM - - CH - - - FAD binding domain
HGBEPDGP_00842 2.57e-171 - - - M - - - Membrane
HGBEPDGP_00843 4.11e-251 yetN - - S - - - Protein of unknown function (DUF3900)
HGBEPDGP_00844 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
HGBEPDGP_00845 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
HGBEPDGP_00846 2.41e-187 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
HGBEPDGP_00847 1.37e-219 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
HGBEPDGP_00848 3.99e-231 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
HGBEPDGP_00849 2.44e-286 yfnE - - S - - - Glycosyltransferase like family 2
HGBEPDGP_00850 2.34e-243 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
HGBEPDGP_00851 6.21e-268 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HGBEPDGP_00852 9.43e-171 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HGBEPDGP_00853 2.4e-312 yfnA - - E ko:K03294 - ko00000 amino acid
HGBEPDGP_00854 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HGBEPDGP_00855 5.14e-161 yfmS - - NT - - - chemotaxis protein
HGBEPDGP_00856 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HGBEPDGP_00857 6.48e-99 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
HGBEPDGP_00858 3.03e-91 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
HGBEPDGP_00859 7.24e-265 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
HGBEPDGP_00860 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HGBEPDGP_00861 1.2e-262 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
HGBEPDGP_00862 2.55e-105 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
HGBEPDGP_00863 6.98e-241 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
HGBEPDGP_00864 1.72e-268 - - - G - - - Major Facilitator Superfamily
HGBEPDGP_00865 0.0 pkn1 - - S - - - Sulfatase-modifying factor enzyme 1
HGBEPDGP_00866 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HGBEPDGP_00867 4.94e-222 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGBEPDGP_00868 4.72e-220 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGBEPDGP_00869 7.58e-217 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HGBEPDGP_00870 1.06e-31 - - - S - - - Protein of unknown function (DUF3212)
HGBEPDGP_00871 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
HGBEPDGP_00872 4.06e-306 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
HGBEPDGP_00873 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HGBEPDGP_00874 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HGBEPDGP_00875 3.96e-154 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HGBEPDGP_00876 1.45e-232 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
HGBEPDGP_00878 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
HGBEPDGP_00879 6.92e-192 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HGBEPDGP_00880 4.6e-274 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HGBEPDGP_00881 2.54e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
HGBEPDGP_00882 5.91e-158 yflK - - S - - - protein conserved in bacteria
HGBEPDGP_00883 1.1e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
HGBEPDGP_00884 9.81e-27 yflI - - - - - - -
HGBEPDGP_00885 2.1e-65 yflH - - S - - - Protein of unknown function (DUF3243)
HGBEPDGP_00886 6.62e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
HGBEPDGP_00887 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HGBEPDGP_00888 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
HGBEPDGP_00889 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
HGBEPDGP_00890 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
HGBEPDGP_00891 2.19e-249 yfkT - - E ko:K06309 - ko00000 Spore germination protein
HGBEPDGP_00893 9.28e-271 yfkR - - S ko:K06297,ko:K06308 - ko00000 spore germination
HGBEPDGP_00894 0.0 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
HGBEPDGP_00895 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HGBEPDGP_00896 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
HGBEPDGP_00897 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
HGBEPDGP_00898 5.27e-161 frp - - C - - - nitroreductase
HGBEPDGP_00899 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HGBEPDGP_00900 5.48e-114 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
HGBEPDGP_00901 2.07e-264 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HGBEPDGP_00902 7.27e-42 yfkK - - S - - - Belongs to the UPF0435 family
HGBEPDGP_00903 9.78e-107 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HGBEPDGP_00904 1.03e-66 yfkI - - S - - - gas vesicle protein
HGBEPDGP_00905 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
HGBEPDGP_00906 1.64e-12 - - - - - - - -
HGBEPDGP_00907 2.7e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HGBEPDGP_00908 5.44e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
HGBEPDGP_00909 3.69e-189 yfkD - - S - - - YfkD-like protein
HGBEPDGP_00910 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
HGBEPDGP_00911 7.17e-283 yfkA - - S - - - YfkB-like domain
HGBEPDGP_00912 3.26e-36 yfjT - - - - - - -
HGBEPDGP_00913 4.19e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
HGBEPDGP_00914 5.16e-189 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HGBEPDGP_00915 7.8e-237 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
HGBEPDGP_00916 2.76e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HGBEPDGP_00917 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HGBEPDGP_00918 3.04e-59 - - - S - - - YfzA-like protein
HGBEPDGP_00919 3.47e-243 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HGBEPDGP_00920 9.55e-111 yfjM - - S - - - Psort location Cytoplasmic, score
HGBEPDGP_00921 9.2e-243 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HGBEPDGP_00922 2.64e-242 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HGBEPDGP_00923 2.7e-261 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HGBEPDGP_00924 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HGBEPDGP_00925 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
HGBEPDGP_00926 2.75e-34 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
HGBEPDGP_00927 7.42e-75 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
HGBEPDGP_00928 1.9e-109 - - - S - - - Family of unknown function (DUF5381)
HGBEPDGP_00929 3.83e-161 yfjC - - - - - - -
HGBEPDGP_00930 6.91e-241 yfjB - - - - - - -
HGBEPDGP_00931 1.6e-60 yfjA - - S - - - Belongs to the WXG100 family
HGBEPDGP_00932 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HGBEPDGP_00933 2.05e-179 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
HGBEPDGP_00934 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HGBEPDGP_00935 0.0 yobO - - M - - - COG5434 Endopolygalacturonase
HGBEPDGP_00936 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
HGBEPDGP_00937 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HGBEPDGP_00938 3.34e-83 yfiD3 - - S - - - DoxX
HGBEPDGP_00939 7.28e-209 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
HGBEPDGP_00941 1.7e-272 baeS - - T - - - Histidine kinase
HGBEPDGP_00942 3.51e-145 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
HGBEPDGP_00943 1.53e-214 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HGBEPDGP_00944 1.78e-265 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HGBEPDGP_00945 1.1e-258 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
HGBEPDGP_00946 1.89e-128 padR - - K - - - transcriptional
HGBEPDGP_00947 3.2e-127 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
HGBEPDGP_00948 5.4e-252 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HGBEPDGP_00949 9.81e-129 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
HGBEPDGP_00950 0.0 yfiU - - EGP - - - the major facilitator superfamily
HGBEPDGP_00951 2.11e-103 yfiV - - K - - - transcriptional
HGBEPDGP_00952 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HGBEPDGP_00953 1.56e-230 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HGBEPDGP_00954 8.91e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGBEPDGP_00955 7.36e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGBEPDGP_00956 7.61e-215 yfhB - - S - - - PhzF family
HGBEPDGP_00957 2.87e-138 yfhC - - C - - - nitroreductase
HGBEPDGP_00958 8.86e-35 yfhD - - S - - - YfhD-like protein
HGBEPDGP_00960 3.11e-219 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
HGBEPDGP_00961 9.32e-181 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
HGBEPDGP_00962 4.8e-67 yfhH - - S - - - Protein of unknown function (DUF1811)
HGBEPDGP_00963 2.34e-266 yfhI - - EGP - - - -transporter
HGBEPDGP_00964 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
HGBEPDGP_00965 8.95e-60 yfhJ - - S - - - WVELL protein
HGBEPDGP_00966 2.32e-115 yfhK - - T - - - Bacterial SH3 domain homologues
HGBEPDGP_00967 1.81e-65 yfhL - - S - - - SdpI/YhfL protein family
HGBEPDGP_00968 1.87e-216 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
HGBEPDGP_00969 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
HGBEPDGP_00970 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
HGBEPDGP_00971 7.22e-237 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
HGBEPDGP_00972 1.2e-267 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
HGBEPDGP_00973 1.73e-48 yfhS - - - - - - -
HGBEPDGP_00974 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGBEPDGP_00975 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
HGBEPDGP_00976 1.88e-63 ygaB - - S - - - YgaB-like protein
HGBEPDGP_00977 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
HGBEPDGP_00978 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
HGBEPDGP_00979 1.87e-238 ygaE - - S - - - Membrane
HGBEPDGP_00980 5.64e-313 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
HGBEPDGP_00981 1.19e-112 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
HGBEPDGP_00982 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
HGBEPDGP_00983 5.46e-74 ygzB - - S - - - UPF0295 protein
HGBEPDGP_00984 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
HGBEPDGP_00985 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HGBEPDGP_01002 6.37e-185 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
HGBEPDGP_01003 1.58e-36 - - - - - - - -
HGBEPDGP_01004 3.18e-169 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
HGBEPDGP_01005 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HGBEPDGP_01006 1.1e-291 ygaK - - C - - - Berberine and berberine like
HGBEPDGP_01007 3.15e-28 ygaK - - C - - - Berberine and berberine like
HGBEPDGP_01009 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
HGBEPDGP_01010 9.01e-179 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HGBEPDGP_01011 8.45e-218 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
HGBEPDGP_01012 4.82e-189 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HGBEPDGP_01013 2.2e-274 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
HGBEPDGP_01015 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HGBEPDGP_01016 2.79e-102 ygaO - - - - - - -
HGBEPDGP_01017 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
HGBEPDGP_01019 1.92e-147 yhzB - - S - - - B3/4 domain
HGBEPDGP_01020 1.7e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HGBEPDGP_01021 1.32e-223 yhbB - - S - - - Putative amidase domain
HGBEPDGP_01022 6.53e-113 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HGBEPDGP_01023 3.4e-143 yhbD - - K - - - Protein of unknown function (DUF4004)
HGBEPDGP_01024 2.66e-95 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
HGBEPDGP_01025 4.28e-105 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
HGBEPDGP_01026 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
HGBEPDGP_01027 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
HGBEPDGP_01028 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
HGBEPDGP_01029 2.67e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
HGBEPDGP_01030 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
HGBEPDGP_01031 9.84e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
HGBEPDGP_01032 3.95e-59 yhcC - - - - - - -
HGBEPDGP_01033 1.03e-69 - - - - - - - -
HGBEPDGP_01034 1.67e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
HGBEPDGP_01035 3.38e-158 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HGBEPDGP_01036 1.85e-212 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HGBEPDGP_01037 1.4e-211 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HGBEPDGP_01038 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
HGBEPDGP_01039 1.34e-195 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HGBEPDGP_01040 7.08e-251 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
HGBEPDGP_01041 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HGBEPDGP_01042 1.13e-70 yhcM - - - - - - -
HGBEPDGP_01043 1.74e-107 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HGBEPDGP_01044 3.64e-223 yhcP - - - - - - -
HGBEPDGP_01045 1.68e-146 yhcQ - - M - - - Spore coat protein
HGBEPDGP_01046 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HGBEPDGP_01047 7.24e-134 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
HGBEPDGP_01048 4.78e-218 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HGBEPDGP_01049 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
HGBEPDGP_01050 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
HGBEPDGP_01051 4.32e-155 yhcW - - S ko:K07025 - ko00000 hydrolase
HGBEPDGP_01052 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HGBEPDGP_01053 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HGBEPDGP_01054 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HGBEPDGP_01055 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HGBEPDGP_01056 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HGBEPDGP_01057 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HGBEPDGP_01058 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
HGBEPDGP_01059 7.33e-270 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
HGBEPDGP_01060 7.42e-142 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGBEPDGP_01061 5.68e-117 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
HGBEPDGP_01062 1.65e-51 yhdB - - S - - - YhdB-like protein
HGBEPDGP_01063 1.25e-72 yhdC - - S - - - Protein of unknown function (DUF3889)
HGBEPDGP_01064 1.39e-274 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
HGBEPDGP_01065 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
HGBEPDGP_01066 5.29e-307 ygxB - - M - - - Conserved TM helix
HGBEPDGP_01067 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
HGBEPDGP_01068 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
HGBEPDGP_01069 7.21e-204 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
HGBEPDGP_01070 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
HGBEPDGP_01071 1.45e-258 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HGBEPDGP_01072 1.58e-205 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGBEPDGP_01073 9.83e-316 yhdG - - E ko:K03294 - ko00000 amino acid
HGBEPDGP_01074 2.48e-309 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HGBEPDGP_01075 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HGBEPDGP_01076 2.05e-99 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGBEPDGP_01077 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
HGBEPDGP_01078 3.54e-257 yhdL - - S - - - Sigma factor regulator N-terminal
HGBEPDGP_01079 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HGBEPDGP_01080 1.93e-243 yhdN - - C - - - Aldo keto reductase
HGBEPDGP_01081 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HGBEPDGP_01082 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HGBEPDGP_01083 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
HGBEPDGP_01084 2.08e-283 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HGBEPDGP_01085 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
HGBEPDGP_01086 2.48e-66 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HGBEPDGP_01087 3.38e-86 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HGBEPDGP_01088 3.15e-173 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HGBEPDGP_01089 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
HGBEPDGP_01090 9.73e-239 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
HGBEPDGP_01091 1.19e-179 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HGBEPDGP_01092 1.63e-199 nodB1 - - G - - - deacetylase
HGBEPDGP_01093 3.16e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HGBEPDGP_01094 1.71e-301 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
HGBEPDGP_01095 1.53e-108 nhaX - - T - - - Belongs to the universal stress protein A family
HGBEPDGP_01096 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HGBEPDGP_01097 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HGBEPDGP_01098 1.29e-140 yheG - - GM - - - NAD(P)H-binding
HGBEPDGP_01099 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
HGBEPDGP_01100 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
HGBEPDGP_01101 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
HGBEPDGP_01102 3.37e-276 yheC - - HJ - - - YheC/D like ATP-grasp
HGBEPDGP_01103 1.39e-257 yheB - - S - - - Belongs to the UPF0754 family
HGBEPDGP_01104 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
HGBEPDGP_01105 2.24e-262 yhaZ - - L - - - DNA alkylation repair enzyme
HGBEPDGP_01106 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
HGBEPDGP_01107 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
HGBEPDGP_01108 7.54e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
HGBEPDGP_01109 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
HGBEPDGP_01111 1.6e-172 yhaR - - I - - - enoyl-CoA hydratase
HGBEPDGP_01112 2.29e-36 - - - S - - - YhzD-like protein
HGBEPDGP_01113 1.31e-213 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HGBEPDGP_01114 5.99e-271 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
HGBEPDGP_01115 2.22e-299 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
HGBEPDGP_01116 0.0 yhaN - - L - - - AAA domain
HGBEPDGP_01117 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
HGBEPDGP_01118 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
HGBEPDGP_01119 2.29e-179 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HGBEPDGP_01120 1.4e-116 yhaK - - S - - - Putative zincin peptidase
HGBEPDGP_01121 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
HGBEPDGP_01122 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
HGBEPDGP_01123 1.74e-54 yhaH - - S - - - YtxH-like protein
HGBEPDGP_01124 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
HGBEPDGP_01125 2.51e-260 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HGBEPDGP_01126 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HGBEPDGP_01127 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
HGBEPDGP_01128 1.72e-269 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HGBEPDGP_01129 1.01e-161 ecsC - - S - - - EcsC protein family
HGBEPDGP_01130 1.48e-289 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HGBEPDGP_01131 2.31e-313 yhfA - - C - - - membrane
HGBEPDGP_01132 1.23e-45 - - - C - - - Rubrerythrin
HGBEPDGP_01133 1.31e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
HGBEPDGP_01134 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HGBEPDGP_01135 1.24e-257 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HGBEPDGP_01136 3.99e-230 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
HGBEPDGP_01137 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HGBEPDGP_01138 1e-132 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
HGBEPDGP_01139 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
HGBEPDGP_01140 8.77e-237 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HGBEPDGP_01141 1.61e-178 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
HGBEPDGP_01142 2.68e-253 yhfE - - G - - - peptidase M42
HGBEPDGP_01143 6.22e-93 - - - S - - - ASCH
HGBEPDGP_01144 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HGBEPDGP_01145 5.93e-183 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HGBEPDGP_01146 4.06e-245 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
HGBEPDGP_01147 1.01e-141 yhfK - - GM - - - NmrA-like family
HGBEPDGP_01148 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
HGBEPDGP_01149 5.6e-85 yhfM - - - - - - -
HGBEPDGP_01150 9.64e-308 yhfN - - O - - - Peptidase M48
HGBEPDGP_01151 6.91e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HGBEPDGP_01152 8.5e-100 - - - K - - - acetyltransferase
HGBEPDGP_01153 1.39e-231 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
HGBEPDGP_01154 2.27e-222 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
HGBEPDGP_01155 9.64e-141 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
HGBEPDGP_01156 7.05e-249 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HGBEPDGP_01157 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
HGBEPDGP_01158 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HGBEPDGP_01159 1.85e-260 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
HGBEPDGP_01160 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
HGBEPDGP_01161 7.82e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGBEPDGP_01162 9.84e-45 yhzC - - S - - - IDEAL
HGBEPDGP_01163 6.29e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
HGBEPDGP_01164 2.55e-216 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HGBEPDGP_01165 3.27e-53 yhjA - - S - - - Excalibur calcium-binding domain
HGBEPDGP_01166 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HGBEPDGP_01167 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
HGBEPDGP_01168 2.57e-78 yhjD - - - - - - -
HGBEPDGP_01169 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
HGBEPDGP_01170 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HGBEPDGP_01171 0.0 yhjG - - CH - - - FAD binding domain
HGBEPDGP_01172 3.29e-121 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
HGBEPDGP_01173 2.46e-270 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
HGBEPDGP_01174 7.71e-255 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HGBEPDGP_01175 1.25e-203 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
HGBEPDGP_01176 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
HGBEPDGP_01177 1.77e-238 yhjM - - K - - - Transcriptional regulator
HGBEPDGP_01178 8.42e-244 yhjN - - S ko:K07120 - ko00000 membrane
HGBEPDGP_01179 1.04e-271 - - - EGP - - - Transmembrane secretion effector
HGBEPDGP_01180 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
HGBEPDGP_01181 2.19e-100 yhjR - - S - - - Rubrerythrin
HGBEPDGP_01182 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
HGBEPDGP_01183 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HGBEPDGP_01184 1.2e-281 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HGBEPDGP_01185 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
HGBEPDGP_01186 7.78e-66 yisB - - V - - - COG1403 Restriction endonuclease
HGBEPDGP_01187 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
HGBEPDGP_01188 4.08e-88 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
HGBEPDGP_01189 7.36e-34 gerPD - - S ko:K06302 - ko00000 Spore germination protein
HGBEPDGP_01190 2.88e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
HGBEPDGP_01191 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
HGBEPDGP_01192 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
HGBEPDGP_01193 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
HGBEPDGP_01194 8.94e-221 cotH - - M ko:K06330 - ko00000 Spore Coat
HGBEPDGP_01195 7.64e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HGBEPDGP_01196 1.02e-74 yisL - - S - - - UPF0344 protein
HGBEPDGP_01197 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HGBEPDGP_01198 7.42e-132 yisN - - S - - - Protein of unknown function (DUF2777)
HGBEPDGP_01199 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HGBEPDGP_01200 1.07e-114 yizA - - S - - - Damage-inducible protein DinB
HGBEPDGP_01201 1.54e-189 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
HGBEPDGP_01202 1.01e-310 yisQ - - V - - - Mate efflux family protein
HGBEPDGP_01203 4.04e-207 yisR - - K - - - Transcriptional regulator
HGBEPDGP_01204 1.83e-235 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HGBEPDGP_01205 6.03e-248 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HGBEPDGP_01206 2.44e-120 yisT - - S - - - DinB family
HGBEPDGP_01207 2.47e-136 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
HGBEPDGP_01208 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HGBEPDGP_01209 2.5e-95 yisX - - S - - - Pentapeptide repeats (9 copies)
HGBEPDGP_01210 2.25e-199 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HGBEPDGP_01211 4.06e-145 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
HGBEPDGP_01212 5.36e-293 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
HGBEPDGP_01213 3.72e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
HGBEPDGP_01214 1.34e-162 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
HGBEPDGP_01215 4.31e-180 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
HGBEPDGP_01216 6.77e-145 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HGBEPDGP_01217 2.14e-283 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
HGBEPDGP_01218 1.01e-291 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HGBEPDGP_01219 1.4e-200 yitH - - K - - - Acetyltransferase (GNAT) domain
HGBEPDGP_01220 5.09e-92 - - - S - - - Acetyltransferase (GNAT) domain
HGBEPDGP_01221 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HGBEPDGP_01222 1.06e-77 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
HGBEPDGP_01223 1.94e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
HGBEPDGP_01224 4.16e-122 - - - - - - - -
HGBEPDGP_01225 1.42e-218 - - - - - - - -
HGBEPDGP_01226 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
HGBEPDGP_01227 1.2e-76 - - - K - - - Transcriptional regulator PadR-like family
HGBEPDGP_01228 6.11e-120 - - - - - - - -
HGBEPDGP_01229 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
HGBEPDGP_01230 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
HGBEPDGP_01231 9.13e-202 yitS - - S - - - protein conserved in bacteria
HGBEPDGP_01232 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HGBEPDGP_01233 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
HGBEPDGP_01234 4.11e-25 - - - S - - - Protein of unknown function (DUF3813)
HGBEPDGP_01235 1.92e-08 - - - - - - - -
HGBEPDGP_01236 5.29e-199 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
HGBEPDGP_01237 1.98e-182 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
HGBEPDGP_01238 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
HGBEPDGP_01239 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
HGBEPDGP_01240 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
HGBEPDGP_01241 3.24e-114 yitZ - - G - - - Major Facilitator Superfamily
HGBEPDGP_01242 7.41e-255 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HGBEPDGP_01243 7.4e-295 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HGBEPDGP_01244 5.4e-177 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
HGBEPDGP_01245 1.69e-278 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
HGBEPDGP_01246 1.4e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HGBEPDGP_01247 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
HGBEPDGP_01248 3.66e-226 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HGBEPDGP_01249 2.51e-39 yjzC - - S - - - YjzC-like protein
HGBEPDGP_01250 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
HGBEPDGP_01251 2.42e-182 yjaU - - I - - - carboxylic ester hydrolase activity
HGBEPDGP_01252 5.41e-134 yjaV - - - - - - -
HGBEPDGP_01253 6.4e-235 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
HGBEPDGP_01254 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
HGBEPDGP_01255 2.67e-38 yjzB - - - - - - -
HGBEPDGP_01256 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HGBEPDGP_01257 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HGBEPDGP_01258 9.48e-193 yjaZ - - O - - - Zn-dependent protease
HGBEPDGP_01259 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HGBEPDGP_01260 2.07e-237 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HGBEPDGP_01261 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
HGBEPDGP_01262 3.73e-213 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGBEPDGP_01263 1.03e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGBEPDGP_01264 7.51e-189 yjbA - - S - - - Belongs to the UPF0736 family
HGBEPDGP_01265 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
HGBEPDGP_01266 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HGBEPDGP_01267 1.03e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGBEPDGP_01268 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGBEPDGP_01269 3.92e-249 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HGBEPDGP_01270 3.12e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HGBEPDGP_01271 9.6e-260 yjbB - - EGP - - - Major Facilitator Superfamily
HGBEPDGP_01272 8.88e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGBEPDGP_01273 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HGBEPDGP_01274 7.1e-144 yjbE - - P - - - Integral membrane protein TerC family
HGBEPDGP_01275 4.65e-149 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HGBEPDGP_01276 4.38e-282 coiA - - S ko:K06198 - ko00000 Competence protein
HGBEPDGP_01277 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
HGBEPDGP_01278 2.68e-28 - - - - - - - -
HGBEPDGP_01280 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
HGBEPDGP_01281 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
HGBEPDGP_01282 7.22e-129 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HGBEPDGP_01283 4.94e-128 yjbK - - S - - - protein conserved in bacteria
HGBEPDGP_01284 1.87e-81 yjbL - - S - - - Belongs to the UPF0738 family
HGBEPDGP_01285 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
HGBEPDGP_01286 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HGBEPDGP_01287 9.4e-206 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HGBEPDGP_01288 8.09e-181 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HGBEPDGP_01289 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HGBEPDGP_01290 5.7e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HGBEPDGP_01291 4.01e-139 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
HGBEPDGP_01292 1.09e-275 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
HGBEPDGP_01293 2.18e-41 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
HGBEPDGP_01294 2.76e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HGBEPDGP_01295 2.94e-236 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HGBEPDGP_01296 4.85e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HGBEPDGP_01297 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
HGBEPDGP_01298 5.16e-104 yjbX - - S - - - Spore coat protein
HGBEPDGP_01299 3.92e-107 cotZ - - S ko:K06344 - ko00000 Spore coat protein
HGBEPDGP_01300 6.3e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
HGBEPDGP_01301 1.23e-95 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
HGBEPDGP_01302 9.3e-32 cotW - - - ko:K06341 - ko00000 -
HGBEPDGP_01303 2.34e-66 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
HGBEPDGP_01304 1.23e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
HGBEPDGP_01307 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
HGBEPDGP_01308 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HGBEPDGP_01309 6.31e-51 - - - - - - - -
HGBEPDGP_01310 9.05e-93 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGBEPDGP_01311 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
HGBEPDGP_01312 1.91e-177 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
HGBEPDGP_01313 1.98e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HGBEPDGP_01314 7.47e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HGBEPDGP_01315 1.42e-102 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
HGBEPDGP_01316 1.05e-273 yjcL - - S - - - Protein of unknown function (DUF819)
HGBEPDGP_01319 1.33e-50 - - - - - - - -
HGBEPDGP_01321 2.35e-295 - - - M - - - nucleic acid phosphodiester bond hydrolysis
HGBEPDGP_01324 1.42e-09 - - - S - - - YolD-like protein
HGBEPDGP_01325 1.92e-47 - - - - - - - -
HGBEPDGP_01326 3.94e-26 - - - - - - - -
HGBEPDGP_01327 2.49e-07 - - - - - - - -
HGBEPDGP_01328 1.27e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
HGBEPDGP_01329 2.81e-180 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
HGBEPDGP_01330 0.000388 - - - - - - - -
HGBEPDGP_01331 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
HGBEPDGP_01332 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HGBEPDGP_01333 5.95e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HGBEPDGP_01334 5.1e-73 yjdF3 - - S - - - Protein of unknown function (DUF2992)
HGBEPDGP_01335 5.12e-117 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HGBEPDGP_01337 1.12e-101 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HGBEPDGP_01338 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
HGBEPDGP_01339 2.31e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
HGBEPDGP_01340 5.31e-224 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HGBEPDGP_01342 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
HGBEPDGP_01343 2.22e-108 - - - S - - - Protein of unknown function (DUF2690)
HGBEPDGP_01344 1.95e-30 yjfB - - S - - - Putative motility protein
HGBEPDGP_01345 1.42e-213 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
HGBEPDGP_01346 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
HGBEPDGP_01347 4.96e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
HGBEPDGP_01348 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
HGBEPDGP_01349 2.27e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
HGBEPDGP_01351 3.7e-147 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
HGBEPDGP_01353 1.25e-281 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HGBEPDGP_01354 4.84e-277 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HGBEPDGP_01355 1.11e-41 - - - - - - - -
HGBEPDGP_01356 4.82e-186 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
HGBEPDGP_01357 1.82e-155 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
HGBEPDGP_01358 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HGBEPDGP_01359 3.12e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
HGBEPDGP_01360 1e-117 yjlB - - S - - - Cupin domain
HGBEPDGP_01361 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
HGBEPDGP_01362 3.56e-279 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HGBEPDGP_01363 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
HGBEPDGP_01364 4.34e-314 - - - G ko:K03292 - ko00000 symporter YjmB
HGBEPDGP_01365 2.08e-241 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
HGBEPDGP_01366 9.24e-246 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
HGBEPDGP_01367 3.92e-273 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
HGBEPDGP_01368 5.47e-196 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HGBEPDGP_01369 9.24e-288 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
HGBEPDGP_01370 9.87e-238 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
HGBEPDGP_01371 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
HGBEPDGP_01372 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
HGBEPDGP_01373 1.59e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
HGBEPDGP_01374 2.71e-103 yjoA - - S - - - DinB family
HGBEPDGP_01375 1.67e-311 VCP - - O - - - AAA domain (dynein-related subfamily)
HGBEPDGP_01376 3.5e-271 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HGBEPDGP_01378 1.79e-55 - - - S - - - YCII-related domain
HGBEPDGP_01379 5.12e-216 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
HGBEPDGP_01380 1.35e-80 yjqA - - S - - - Bacterial PH domain
HGBEPDGP_01381 3.73e-137 yjqB - - S - - - Pfam:DUF867
HGBEPDGP_01382 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
HGBEPDGP_01383 1.79e-143 xkdA - - E - - - IrrE N-terminal-like domain
HGBEPDGP_01384 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
HGBEPDGP_01386 3.73e-203 xkdB - - K - - - sequence-specific DNA binding
HGBEPDGP_01387 3.55e-151 xkdC - - L - - - Bacterial dnaA protein
HGBEPDGP_01391 9.88e-111 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HGBEPDGP_01392 7.93e-178 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
HGBEPDGP_01393 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
HGBEPDGP_01394 0.0 yqbA - - S - - - portal protein
HGBEPDGP_01395 9.88e-177 xkdF3 - - L - - - Putative phage serine protease XkdF
HGBEPDGP_01396 3.91e-217 xkdG - - S - - - Phage capsid family
HGBEPDGP_01397 3.85e-81 yqbG - - S - - - Protein of unknown function (DUF3199)
HGBEPDGP_01398 1.5e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
HGBEPDGP_01399 8.3e-115 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
HGBEPDGP_01400 2.87e-101 xkdJ - - - - - - -
HGBEPDGP_01401 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
HGBEPDGP_01402 6.01e-99 xkdM - - S - - - Phage tail tube protein
HGBEPDGP_01403 9.21e-99 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
HGBEPDGP_01404 0.0 xkdO - - L - - - Transglycosylase SLT domain
HGBEPDGP_01405 4.25e-152 xkdP - - S - - - Lysin motif
HGBEPDGP_01406 1.56e-230 xkdQ - - G - - - NLP P60 protein
HGBEPDGP_01407 5.05e-52 xkdR - - S - - - Protein of unknown function (DUF2577)
HGBEPDGP_01408 1.1e-89 xkdS - - S - - - Protein of unknown function (DUF2634)
HGBEPDGP_01409 1.47e-242 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HGBEPDGP_01410 3.23e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
HGBEPDGP_01411 4.43e-56 - - - - - - - -
HGBEPDGP_01412 1.87e-219 - - - - - - - -
HGBEPDGP_01413 1.28e-59 xkdW - - S - - - XkdW protein
HGBEPDGP_01414 6.35e-31 xkdX - - - - - - -
HGBEPDGP_01415 2.21e-193 xepA - - - - - - -
HGBEPDGP_01416 2.21e-51 xhlA - - S - - - Haemolysin XhlA
HGBEPDGP_01417 1.15e-52 xhlB - - S - - - SPP1 phage holin
HGBEPDGP_01418 5.3e-208 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
HGBEPDGP_01419 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
HGBEPDGP_01420 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
HGBEPDGP_01421 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
HGBEPDGP_01422 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
HGBEPDGP_01423 2.57e-309 steT - - E ko:K03294 - ko00000 amino acid
HGBEPDGP_01424 8.07e-233 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HGBEPDGP_01425 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HGBEPDGP_01426 2.21e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
HGBEPDGP_01428 2.41e-284 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HGBEPDGP_01429 1.16e-178 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
HGBEPDGP_01430 1.4e-196 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
HGBEPDGP_01431 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGBEPDGP_01432 9.02e-226 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGBEPDGP_01433 1.35e-236 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HGBEPDGP_01434 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HGBEPDGP_01436 4.26e-228 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
HGBEPDGP_01437 1.24e-259 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
HGBEPDGP_01438 1e-216 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HGBEPDGP_01439 4.88e-236 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HGBEPDGP_01440 9.43e-260 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
HGBEPDGP_01441 2.53e-205 ykgA - - E - - - Amidinotransferase
HGBEPDGP_01442 1.55e-119 ykhA - - I - - - Acyl-CoA hydrolase
HGBEPDGP_01443 2.65e-289 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HGBEPDGP_01444 5.85e-13 - - - - - - - -
HGBEPDGP_01445 3.95e-167 ykjA - - S - - - Protein of unknown function (DUF421)
HGBEPDGP_01446 1.57e-128 ykkA - - S - - - Protein of unknown function (DUF664)
HGBEPDGP_01447 3.59e-128 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HGBEPDGP_01448 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
HGBEPDGP_01449 1.36e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
HGBEPDGP_01450 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HGBEPDGP_01451 3.16e-257 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HGBEPDGP_01452 3.38e-291 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HGBEPDGP_01454 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
HGBEPDGP_01455 1.42e-97 ohrR - - K - - - COG1846 Transcriptional regulators
HGBEPDGP_01456 8.15e-94 ohrB - - O - - - Organic hydroperoxide resistance protein
HGBEPDGP_01457 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
HGBEPDGP_01458 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HGBEPDGP_01459 1.49e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HGBEPDGP_01460 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HGBEPDGP_01461 3.65e-173 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HGBEPDGP_01462 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HGBEPDGP_01463 1.39e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
HGBEPDGP_01464 1.36e-139 ykoF - - S - - - YKOF-related Family
HGBEPDGP_01465 3.03e-159 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGBEPDGP_01466 3.13e-309 ykoH - - T - - - Histidine kinase
HGBEPDGP_01467 2.26e-144 ykoI - - S - - - Peptidase propeptide and YPEB domain
HGBEPDGP_01468 1.3e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
HGBEPDGP_01469 1.45e-08 - - - - - - - -
HGBEPDGP_01471 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
HGBEPDGP_01472 1.49e-70 tnrA - - K - - - transcriptional
HGBEPDGP_01473 1.63e-25 - - - - - - - -
HGBEPDGP_01474 3.04e-36 ykoL - - - - - - -
HGBEPDGP_01475 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
HGBEPDGP_01476 6.37e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HGBEPDGP_01477 1.44e-128 ykoP - - G - - - polysaccharide deacetylase
HGBEPDGP_01478 4.35e-198 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
HGBEPDGP_01479 0.0 ykoS - - - - - - -
HGBEPDGP_01480 5.72e-239 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
HGBEPDGP_01481 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
HGBEPDGP_01482 1.25e-204 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HGBEPDGP_01483 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
HGBEPDGP_01484 1.71e-143 ykoX - - S - - - membrane-associated protein
HGBEPDGP_01485 1.33e-226 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HGBEPDGP_01486 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGBEPDGP_01487 1.63e-212 rsgI - - S - - - Anti-sigma factor N-terminus
HGBEPDGP_01488 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
HGBEPDGP_01489 7.68e-160 ykrK - - S - - - Domain of unknown function (DUF1836)
HGBEPDGP_01490 9.33e-198 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HGBEPDGP_01491 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
HGBEPDGP_01493 1.77e-28 ykzE - - - - - - -
HGBEPDGP_01494 3.34e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
HGBEPDGP_01495 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HGBEPDGP_01496 1.53e-112 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HGBEPDGP_01498 1.33e-252 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HGBEPDGP_01499 2.47e-293 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HGBEPDGP_01500 1.99e-193 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HGBEPDGP_01501 2.67e-293 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HGBEPDGP_01502 2.29e-293 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HGBEPDGP_01503 1.77e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HGBEPDGP_01504 1.84e-146 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HGBEPDGP_01505 8.7e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HGBEPDGP_01506 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
HGBEPDGP_01508 5.62e-93 eag - - - - - - -
HGBEPDGP_01509 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
HGBEPDGP_01510 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
HGBEPDGP_01511 1.31e-169 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
HGBEPDGP_01512 3.23e-178 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
HGBEPDGP_01513 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
HGBEPDGP_01514 2.36e-227 ykvI - - S - - - membrane
HGBEPDGP_01515 2.61e-160 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HGBEPDGP_01516 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
HGBEPDGP_01517 2.06e-178 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HGBEPDGP_01518 1.37e-124 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HGBEPDGP_01519 2.8e-81 ykvN - - K - - - Transcriptional regulator
HGBEPDGP_01520 9.35e-173 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HGBEPDGP_01521 1.82e-273 - - - M - - - Glycosyl transferases group 1
HGBEPDGP_01522 7.56e-48 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
HGBEPDGP_01523 1.75e-204 - - - G - - - Glycosyl hydrolases family 18
HGBEPDGP_01524 8.95e-61 ykvR - - S - - - Protein of unknown function (DUF3219)
HGBEPDGP_01525 5.43e-35 ykvS - - S - - - protein conserved in bacteria
HGBEPDGP_01526 2.5e-39 - - - - - - - -
HGBEPDGP_01527 9.09e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
HGBEPDGP_01528 1.12e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HGBEPDGP_01529 1.31e-113 stoA - - CO - - - thiol-disulfide
HGBEPDGP_01530 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
HGBEPDGP_01531 3.99e-09 - - - - - - - -
HGBEPDGP_01532 1.93e-264 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
HGBEPDGP_01533 6.34e-228 ykvZ - - K - - - Transcriptional regulator
HGBEPDGP_01535 6.87e-168 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
HGBEPDGP_01536 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HGBEPDGP_01537 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
HGBEPDGP_01538 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HGBEPDGP_01539 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
HGBEPDGP_01540 2.13e-257 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
HGBEPDGP_01541 1.06e-167 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGBEPDGP_01542 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HGBEPDGP_01543 4.02e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HGBEPDGP_01544 2.97e-169 ykwD - - J - - - protein with SCP PR1 domains
HGBEPDGP_01545 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HGBEPDGP_01546 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HGBEPDGP_01547 3.44e-282 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HGBEPDGP_01548 1.05e-22 - - - - - - - -
HGBEPDGP_01549 2.86e-215 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
HGBEPDGP_01550 3.71e-110 ykyB - - S - - - YkyB-like protein
HGBEPDGP_01551 2.97e-304 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HGBEPDGP_01552 5.84e-115 ykuD - - S - - - protein conserved in bacteria
HGBEPDGP_01553 2.45e-210 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
HGBEPDGP_01554 2.91e-179 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGBEPDGP_01555 2.05e-297 ykuI - - T - - - Diguanylate phosphodiesterase
HGBEPDGP_01556 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
HGBEPDGP_01557 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
HGBEPDGP_01558 7.83e-38 ykzF - - S - - - Antirepressor AbbA
HGBEPDGP_01559 5.15e-100 ykuL - - S - - - CBS domain
HGBEPDGP_01560 6.52e-216 ccpC - - K - - - Transcriptional regulator
HGBEPDGP_01561 8.34e-109 - - - C ko:K03839 - ko00000 Flavodoxin domain
HGBEPDGP_01562 7.7e-226 ykuO - - - - - - -
HGBEPDGP_01563 6.2e-103 fld - - C ko:K03839 - ko00000 Flavodoxin
HGBEPDGP_01564 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HGBEPDGP_01565 7.66e-274 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HGBEPDGP_01566 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
HGBEPDGP_01567 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
HGBEPDGP_01568 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
HGBEPDGP_01569 1.47e-104 ykuV - - CO - - - thiol-disulfide
HGBEPDGP_01570 4.71e-122 rok - - K - - - Repressor of ComK
HGBEPDGP_01571 2.43e-200 yknT - - - ko:K06437 - ko00000 -
HGBEPDGP_01572 3.75e-141 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HGBEPDGP_01573 1.26e-243 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HGBEPDGP_01574 2.38e-310 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
HGBEPDGP_01575 4.89e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
HGBEPDGP_01576 3.83e-109 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
HGBEPDGP_01577 2.82e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HGBEPDGP_01578 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HGBEPDGP_01579 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HGBEPDGP_01580 5.34e-150 yknW - - S - - - Yip1 domain
HGBEPDGP_01581 8.16e-234 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HGBEPDGP_01582 1.44e-158 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HGBEPDGP_01583 1.92e-265 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
HGBEPDGP_01584 7.41e-176 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
HGBEPDGP_01585 9.99e-216 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
HGBEPDGP_01586 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HGBEPDGP_01587 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HGBEPDGP_01588 5.43e-52 ykoA - - - - - - -
HGBEPDGP_01589 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HGBEPDGP_01590 2.86e-215 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HGBEPDGP_01591 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
HGBEPDGP_01592 1.09e-18 - - - S - - - Uncharacterized protein YkpC
HGBEPDGP_01593 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
HGBEPDGP_01594 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
HGBEPDGP_01595 2.65e-306 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
HGBEPDGP_01596 8.06e-197 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
HGBEPDGP_01597 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
HGBEPDGP_01598 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HGBEPDGP_01599 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HGBEPDGP_01600 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
HGBEPDGP_01601 4.79e-186 ykrA - - S - - - hydrolases of the HAD superfamily
HGBEPDGP_01602 1.14e-130 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HGBEPDGP_01603 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
HGBEPDGP_01604 6.82e-149 ykyA - - L - - - Putative cell-wall binding lipoprotein
HGBEPDGP_01605 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HGBEPDGP_01606 1.75e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HGBEPDGP_01607 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HGBEPDGP_01608 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HGBEPDGP_01609 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
HGBEPDGP_01610 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
HGBEPDGP_01611 1.34e-56 yktA - - S - - - Belongs to the UPF0223 family
HGBEPDGP_01612 1.45e-149 yktB - - S - - - Belongs to the UPF0637 family
HGBEPDGP_01613 4.48e-35 ykzI - - - - - - -
HGBEPDGP_01614 9.48e-195 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
HGBEPDGP_01615 2.98e-100 ykzC - - S - - - Acetyltransferase (GNAT) family
HGBEPDGP_01616 2.88e-220 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HGBEPDGP_01617 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
HGBEPDGP_01618 0.0 ylaA - - - - - - -
HGBEPDGP_01619 1.44e-56 ylaB - - - - - - -
HGBEPDGP_01620 1.45e-114 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HGBEPDGP_01622 1.74e-57 ylaE - - - - - - -
HGBEPDGP_01623 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
HGBEPDGP_01624 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HGBEPDGP_01625 4.4e-63 ylaH - - S - - - YlaH-like protein
HGBEPDGP_01626 8.92e-44 ylaI - - S - - - protein conserved in bacteria
HGBEPDGP_01627 2.97e-127 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HGBEPDGP_01628 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
HGBEPDGP_01629 1.09e-110 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HGBEPDGP_01630 3.49e-219 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HGBEPDGP_01631 5.71e-58 ylaN - - S - - - Belongs to the UPF0358 family
HGBEPDGP_01632 2.87e-270 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HGBEPDGP_01633 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HGBEPDGP_01634 1.65e-211 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HGBEPDGP_01635 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HGBEPDGP_01636 2.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HGBEPDGP_01637 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HGBEPDGP_01638 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HGBEPDGP_01639 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HGBEPDGP_01640 1.04e-214 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
HGBEPDGP_01641 1.61e-81 ylbA - - S - - - YugN-like family
HGBEPDGP_01642 3.09e-97 ylbB - - T - - - COG0517 FOG CBS domain
HGBEPDGP_01643 1.53e-256 ylbC - - S - - - protein with SCP PR1 domains
HGBEPDGP_01644 3.24e-89 ylbD - - S - - - Putative coat protein
HGBEPDGP_01645 1.73e-48 ylbE - - S - - - YlbE-like protein
HGBEPDGP_01646 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
HGBEPDGP_01647 8.8e-52 ylbG - - S - - - UPF0298 protein
HGBEPDGP_01648 1.74e-125 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
HGBEPDGP_01649 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HGBEPDGP_01650 1.58e-281 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
HGBEPDGP_01651 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
HGBEPDGP_01652 3.18e-238 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HGBEPDGP_01653 1.05e-294 ylbM - - S - - - Belongs to the UPF0348 family
HGBEPDGP_01655 1.99e-116 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
HGBEPDGP_01656 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
HGBEPDGP_01657 4.72e-107 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HGBEPDGP_01658 1.33e-115 ylbP - - K - - - n-acetyltransferase
HGBEPDGP_01659 9.62e-216 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HGBEPDGP_01660 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HGBEPDGP_01661 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HGBEPDGP_01662 4.76e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HGBEPDGP_01663 3.42e-68 ftsL - - D - - - Essential cell division protein
HGBEPDGP_01664 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HGBEPDGP_01665 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
HGBEPDGP_01666 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HGBEPDGP_01667 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HGBEPDGP_01668 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HGBEPDGP_01669 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HGBEPDGP_01670 7.74e-257 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HGBEPDGP_01671 1.3e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
HGBEPDGP_01672 1.18e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HGBEPDGP_01673 4.5e-142 ylxW - - S - - - protein conserved in bacteria
HGBEPDGP_01674 1.03e-123 ylxX - - S - - - protein conserved in bacteria
HGBEPDGP_01675 5.37e-76 sbp - - S - - - small basic protein
HGBEPDGP_01676 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HGBEPDGP_01677 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HGBEPDGP_01678 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
HGBEPDGP_01680 1.48e-220 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HGBEPDGP_01681 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGBEPDGP_01682 1.14e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGBEPDGP_01683 1.83e-187 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HGBEPDGP_01684 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
HGBEPDGP_01685 3.58e-51 ylmC - - S - - - sporulation protein
HGBEPDGP_01686 5.94e-200 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
HGBEPDGP_01687 9.03e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HGBEPDGP_01688 4.47e-87 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HGBEPDGP_01689 1.74e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
HGBEPDGP_01690 3.67e-179 ylmH - - S - - - conserved protein, contains S4-like domain
HGBEPDGP_01691 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
HGBEPDGP_01692 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HGBEPDGP_01693 9.18e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
HGBEPDGP_01694 5.47e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HGBEPDGP_01695 3.52e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HGBEPDGP_01696 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HGBEPDGP_01697 3.71e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
HGBEPDGP_01698 1.04e-213 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HGBEPDGP_01699 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HGBEPDGP_01700 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HGBEPDGP_01701 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
HGBEPDGP_01702 1.57e-184 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HGBEPDGP_01703 6.05e-221 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HGBEPDGP_01704 8.94e-162 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HGBEPDGP_01705 8.96e-149 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HGBEPDGP_01707 5.95e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
HGBEPDGP_01708 6.01e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
HGBEPDGP_01709 2.15e-284 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
HGBEPDGP_01710 3.76e-140 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
HGBEPDGP_01711 5.9e-185 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
HGBEPDGP_01712 1.45e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
HGBEPDGP_01713 6.53e-108 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
HGBEPDGP_01714 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
HGBEPDGP_01715 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
HGBEPDGP_01716 8.41e-202 yloC - - S - - - stress-induced protein
HGBEPDGP_01717 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
HGBEPDGP_01718 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HGBEPDGP_01719 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HGBEPDGP_01720 7.28e-286 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HGBEPDGP_01721 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HGBEPDGP_01722 8.3e-110 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HGBEPDGP_01723 1.28e-225 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HGBEPDGP_01724 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HGBEPDGP_01725 5.3e-264 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HGBEPDGP_01726 3.54e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
HGBEPDGP_01727 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HGBEPDGP_01728 3.92e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HGBEPDGP_01729 1.1e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HGBEPDGP_01730 8.13e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
HGBEPDGP_01731 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HGBEPDGP_01732 3.65e-78 yloU - - S - - - protein conserved in bacteria
HGBEPDGP_01733 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
HGBEPDGP_01734 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
HGBEPDGP_01735 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
HGBEPDGP_01736 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HGBEPDGP_01737 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HGBEPDGP_01738 8.33e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HGBEPDGP_01739 1.79e-216 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
HGBEPDGP_01740 3.5e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
HGBEPDGP_01741 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HGBEPDGP_01742 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HGBEPDGP_01743 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HGBEPDGP_01744 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HGBEPDGP_01745 1.67e-114 - - - - - - - -
HGBEPDGP_01746 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HGBEPDGP_01747 9.7e-309 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HGBEPDGP_01748 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HGBEPDGP_01749 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
HGBEPDGP_01750 3.41e-80 ylqD - - S - - - YlqD protein
HGBEPDGP_01751 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HGBEPDGP_01752 2.41e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HGBEPDGP_01753 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HGBEPDGP_01754 4.89e-201 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HGBEPDGP_01755 2.89e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HGBEPDGP_01756 0.0 ylqG - - - - - - -
HGBEPDGP_01757 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
HGBEPDGP_01758 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HGBEPDGP_01759 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HGBEPDGP_01760 2.66e-217 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
HGBEPDGP_01761 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HGBEPDGP_01762 5.45e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HGBEPDGP_01763 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
HGBEPDGP_01764 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HGBEPDGP_01765 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HGBEPDGP_01766 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HGBEPDGP_01767 3.27e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HGBEPDGP_01768 7.54e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
HGBEPDGP_01769 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
HGBEPDGP_01770 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
HGBEPDGP_01771 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HGBEPDGP_01772 1.92e-144 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
HGBEPDGP_01773 1.22e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HGBEPDGP_01774 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
HGBEPDGP_01775 5.08e-84 ylxF - - S - - - MgtE intracellular N domain
HGBEPDGP_01776 1.28e-311 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
HGBEPDGP_01777 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
HGBEPDGP_01778 1.09e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
HGBEPDGP_01779 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
HGBEPDGP_01780 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HGBEPDGP_01781 1.38e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HGBEPDGP_01782 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
HGBEPDGP_01783 7.87e-137 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
HGBEPDGP_01784 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
HGBEPDGP_01785 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
HGBEPDGP_01786 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
HGBEPDGP_01787 2.74e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HGBEPDGP_01788 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HGBEPDGP_01789 5.65e-256 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
HGBEPDGP_01790 1.09e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
HGBEPDGP_01791 2.58e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HGBEPDGP_01792 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
HGBEPDGP_01793 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
HGBEPDGP_01794 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HGBEPDGP_01795 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HGBEPDGP_01796 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGBEPDGP_01797 6.62e-99 ylxL - - - - - - -
HGBEPDGP_01798 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HGBEPDGP_01799 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HGBEPDGP_01800 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HGBEPDGP_01801 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HGBEPDGP_01802 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HGBEPDGP_01803 1.36e-177 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HGBEPDGP_01804 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HGBEPDGP_01805 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HGBEPDGP_01806 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HGBEPDGP_01807 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HGBEPDGP_01808 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HGBEPDGP_01809 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HGBEPDGP_01810 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
HGBEPDGP_01811 6.16e-63 ylxQ - - J - - - ribosomal protein
HGBEPDGP_01812 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HGBEPDGP_01813 7.83e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
HGBEPDGP_01814 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HGBEPDGP_01815 1.17e-217 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HGBEPDGP_01816 3.84e-231 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HGBEPDGP_01817 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HGBEPDGP_01818 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HGBEPDGP_01819 3.98e-230 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
HGBEPDGP_01820 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
HGBEPDGP_01821 1.53e-56 ymxH - - S - - - YlmC YmxH family
HGBEPDGP_01822 5.3e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
HGBEPDGP_01823 8.17e-141 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HGBEPDGP_01824 4.77e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HGBEPDGP_01825 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HGBEPDGP_01826 9.08e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HGBEPDGP_01827 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HGBEPDGP_01828 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
HGBEPDGP_01829 4.94e-44 - - - S - - - YlzJ-like protein
HGBEPDGP_01830 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HGBEPDGP_01831 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
HGBEPDGP_01832 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HGBEPDGP_01833 4.5e-297 albE - - S - - - Peptidase M16
HGBEPDGP_01834 6.8e-309 ymfH - - S - - - zinc protease
HGBEPDGP_01835 1.49e-166 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HGBEPDGP_01836 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
HGBEPDGP_01837 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
HGBEPDGP_01838 3.05e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
HGBEPDGP_01839 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HGBEPDGP_01840 4.33e-299 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
HGBEPDGP_01841 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HGBEPDGP_01842 2.82e-280 pbpX - - V - - - Beta-lactamase
HGBEPDGP_01843 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HGBEPDGP_01844 5.08e-194 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
HGBEPDGP_01845 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
HGBEPDGP_01846 7.12e-254 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HGBEPDGP_01847 2.4e-277 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HGBEPDGP_01848 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HGBEPDGP_01849 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
HGBEPDGP_01850 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
HGBEPDGP_01851 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HGBEPDGP_01852 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HGBEPDGP_01853 2.93e-92 - - - S - - - Regulatory protein YrvL
HGBEPDGP_01855 1.13e-126 ymcC - - S - - - Membrane
HGBEPDGP_01856 3.43e-140 pksA - - K - - - Transcriptional regulator
HGBEPDGP_01857 9.47e-166 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
HGBEPDGP_01858 2.17e-207 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
HGBEPDGP_01860 3.17e-234 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
HGBEPDGP_01861 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
HGBEPDGP_01862 5.46e-51 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
HGBEPDGP_01863 4.36e-303 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HGBEPDGP_01864 9.7e-314 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
HGBEPDGP_01865 2.04e-183 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
HGBEPDGP_01866 4.29e-174 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
HGBEPDGP_01867 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
HGBEPDGP_01868 0.0 - - - Q ko:K13612 - ko00000,ko01004,ko01008 Polyketide synthase of type I
HGBEPDGP_01869 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
HGBEPDGP_01870 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
HGBEPDGP_01871 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
HGBEPDGP_01872 2.79e-294 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HGBEPDGP_01873 9.39e-80 ymzB - - - - - - -
HGBEPDGP_01874 7.65e-207 - - - S - - - Metallo-beta-lactamase superfamily
HGBEPDGP_01875 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
HGBEPDGP_01877 3.96e-163 ymaC - - S - - - Replication protein
HGBEPDGP_01878 8.49e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
HGBEPDGP_01879 6.39e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
HGBEPDGP_01880 2.02e-66 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
HGBEPDGP_01882 5.41e-76 ymaF - - S - - - YmaF family
HGBEPDGP_01883 3.95e-223 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HGBEPDGP_01884 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HGBEPDGP_01885 1.63e-31 - - - - - - - -
HGBEPDGP_01886 1.2e-30 ymzA - - - - - - -
HGBEPDGP_01887 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
HGBEPDGP_01888 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HGBEPDGP_01889 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HGBEPDGP_01890 2.24e-141 - - - - - - - -
HGBEPDGP_01891 3.32e-149 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
HGBEPDGP_01892 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
HGBEPDGP_01893 1.05e-292 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HGBEPDGP_01894 1.67e-310 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HGBEPDGP_01895 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
HGBEPDGP_01896 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HGBEPDGP_01899 6.65e-53 - - - - - - - -
HGBEPDGP_01900 2.02e-51 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
HGBEPDGP_01902 2.19e-11 - - - S - - - LXG domain of WXG superfamily
HGBEPDGP_01904 1.62e-108 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
HGBEPDGP_01905 1.95e-157 - - - S - - - Protein of unknown function (DUF1524)
HGBEPDGP_01906 5.91e-14 - - - - - - - -
HGBEPDGP_01909 9.6e-120 - - - M - - - Glycosyltransferase like family
HGBEPDGP_01910 1.17e-155 - - - H - - - Methionine biosynthesis protein MetW
HGBEPDGP_01911 6.07e-248 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
HGBEPDGP_01912 3.49e-271 - - - H - - - N-terminal domain of galactosyltransferase
HGBEPDGP_01914 7.11e-127 ynaD - - J - - - Acetyltransferase (GNAT) domain
HGBEPDGP_01916 3.45e-90 - - - S - - - CAAX protease self-immunity
HGBEPDGP_01917 2.38e-11 ywlA - - S - - - Uncharacterised protein family (UPF0715)
HGBEPDGP_01918 2.79e-30 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
HGBEPDGP_01919 1.1e-142 - - - S - - - Domain of unknown function (DUF3885)
HGBEPDGP_01920 1.14e-61 ynaF - - - - - - -
HGBEPDGP_01923 1.76e-109 - - - E - - - phosphoribosylanthranilate isomerase activity
HGBEPDGP_01924 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
HGBEPDGP_01925 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
HGBEPDGP_01926 5.85e-274 xylR - - GK - - - ROK family
HGBEPDGP_01927 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
HGBEPDGP_01928 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
HGBEPDGP_01929 2.06e-144 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
HGBEPDGP_01930 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HGBEPDGP_01931 5.06e-280 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HGBEPDGP_01932 3.86e-107 - - - S - - - Protein of unknown function (DUF2691)
HGBEPDGP_01933 3.01e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
HGBEPDGP_01934 7.54e-22 - - - - - - - -
HGBEPDGP_01937 2.75e-210 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HGBEPDGP_01939 4.44e-172 - - - S - - - Domain of unknown function, YrpD
HGBEPDGP_01942 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
HGBEPDGP_01943 8.92e-96 - - - - - - - -
HGBEPDGP_01944 1.05e-102 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
HGBEPDGP_01947 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
HGBEPDGP_01948 1.95e-250 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
HGBEPDGP_01949 5.57e-289 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
HGBEPDGP_01950 1.85e-198 yndG - - S - - - DoxX-like family
HGBEPDGP_01951 3.46e-149 - - - S - - - Domain of unknown function (DUF4166)
HGBEPDGP_01952 0.0 yndJ - - S - - - YndJ-like protein
HGBEPDGP_01954 3.26e-175 yndL - - S - - - Replication protein
HGBEPDGP_01955 1.32e-96 yndM - - S - - - Protein of unknown function (DUF2512)
HGBEPDGP_01956 4.44e-104 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HGBEPDGP_01957 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HGBEPDGP_01958 2.44e-64 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HGBEPDGP_01959 2.29e-144 yneB - - L - - - resolvase
HGBEPDGP_01960 1.15e-43 ynzC - - S - - - UPF0291 protein
HGBEPDGP_01961 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HGBEPDGP_01962 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
HGBEPDGP_01963 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
HGBEPDGP_01964 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
HGBEPDGP_01965 4.13e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
HGBEPDGP_01966 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
HGBEPDGP_01967 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
HGBEPDGP_01968 3.97e-97 yneK - - S - - - Protein of unknown function (DUF2621)
HGBEPDGP_01969 5.77e-85 cotM - - O ko:K06335 - ko00000 Spore coat protein
HGBEPDGP_01970 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
HGBEPDGP_01971 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
HGBEPDGP_01972 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HGBEPDGP_01973 2.53e-118 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HGBEPDGP_01974 9.26e-10 - - - S - - - Fur-regulated basic protein B
HGBEPDGP_01976 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
HGBEPDGP_01977 1.64e-94 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
HGBEPDGP_01978 2.32e-71 yneQ - - - - - - -
HGBEPDGP_01979 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
HGBEPDGP_01980 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HGBEPDGP_01981 1.21e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
HGBEPDGP_01982 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HGBEPDGP_01983 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HGBEPDGP_01984 1.82e-18 - - - - - - - -
HGBEPDGP_01985 1.06e-75 ynfC - - - - - - -
HGBEPDGP_01986 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
HGBEPDGP_01987 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
HGBEPDGP_01989 9.85e-317 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
HGBEPDGP_01990 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
HGBEPDGP_01991 4.06e-102 yngA - - S - - - membrane
HGBEPDGP_01992 7.53e-208 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HGBEPDGP_01993 2.01e-134 yngC - - S - - - membrane-associated protein
HGBEPDGP_01994 7.39e-296 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
HGBEPDGP_01995 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HGBEPDGP_01996 1.42e-173 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
HGBEPDGP_01997 3.89e-211 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
HGBEPDGP_01998 1.19e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
HGBEPDGP_01999 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
HGBEPDGP_02000 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HGBEPDGP_02001 7.28e-266 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
HGBEPDGP_02002 2.97e-07 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HGBEPDGP_02003 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
HGBEPDGP_02004 2.48e-83 yngL - - S - - - Protein of unknown function (DUF1360)
HGBEPDGP_02005 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
HGBEPDGP_02006 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGBEPDGP_02007 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGBEPDGP_02008 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGBEPDGP_02009 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGBEPDGP_02010 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
HGBEPDGP_02011 9.53e-241 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HGBEPDGP_02012 1.33e-310 yoeA - - V - - - MATE efflux family protein
HGBEPDGP_02013 4.13e-127 yoeB - - S - - - IseA DL-endopeptidase inhibitor
HGBEPDGP_02015 1.14e-124 - - - L - - - Integrase
HGBEPDGP_02016 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
HGBEPDGP_02017 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
HGBEPDGP_02018 1.3e-202 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
HGBEPDGP_02019 4.18e-237 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HGBEPDGP_02020 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HGBEPDGP_02021 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
HGBEPDGP_02022 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
HGBEPDGP_02023 1.91e-261 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HGBEPDGP_02024 2.24e-184 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HGBEPDGP_02025 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HGBEPDGP_02026 7.3e-156 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HGBEPDGP_02027 1.7e-54 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
HGBEPDGP_02028 5.79e-171 yoxB - - - - - - -
HGBEPDGP_02029 7.43e-119 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HGBEPDGP_02030 1.7e-300 - - - S - - - Arylsulfotransferase (ASST)
HGBEPDGP_02031 2.75e-160 - 3.1.1.3 - I ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 Lipase (class 3)
HGBEPDGP_02032 1.84e-299 yoaB - - EGP - - - the major facilitator superfamily
HGBEPDGP_02033 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
HGBEPDGP_02034 3.36e-234 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGBEPDGP_02035 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HGBEPDGP_02036 7.24e-45 yoaF - - - - - - -
HGBEPDGP_02039 1.46e-19 - - - - - - - -
HGBEPDGP_02040 2.99e-55 - - - S - - - Protein of unknown function (DUF4025)
HGBEPDGP_02041 6.22e-308 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
HGBEPDGP_02042 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
HGBEPDGP_02043 2.61e-171 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
HGBEPDGP_02044 1.79e-145 yoaK - - S - - - Membrane
HGBEPDGP_02045 1.43e-252 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
HGBEPDGP_02046 2.07e-170 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
HGBEPDGP_02049 8.89e-293 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
HGBEPDGP_02051 3.86e-183 yoaP - - K - - - YoaP-like
HGBEPDGP_02052 3.01e-87 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
HGBEPDGP_02054 1.87e-113 - - - - - - - -
HGBEPDGP_02055 1.04e-217 yoaR - - V - - - vancomycin resistance protein
HGBEPDGP_02056 3.22e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
HGBEPDGP_02057 7.19e-41 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
HGBEPDGP_02058 1.57e-188 yoaT - - S - - - Protein of unknown function (DUF817)
HGBEPDGP_02059 1.11e-201 yoaU - - K - - - LysR substrate binding domain
HGBEPDGP_02060 1.51e-200 yoaV - - EG - - - EamA-like transporter family
HGBEPDGP_02061 1.89e-100 yoaW - - - - - - -
HGBEPDGP_02062 5.94e-148 lin0465 - - S - - - DJ-1/PfpI family
HGBEPDGP_02063 2.09e-214 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
HGBEPDGP_02066 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
HGBEPDGP_02067 1.07e-156 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
HGBEPDGP_02068 1e-47 - - - S - - - TM2 domain
HGBEPDGP_02069 7.63e-74 - - - K - - - Helix-turn-helix
HGBEPDGP_02072 7.44e-66 - - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
HGBEPDGP_02077 1.56e-12 ywlA - - S - - - Uncharacterised protein family (UPF0715)
HGBEPDGP_02081 6.81e-66 - - - S - - - Tetratricopeptide repeat
HGBEPDGP_02082 2.51e-74 - - - J - - - tRNA cytidylyltransferase activity
HGBEPDGP_02090 8.49e-265 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HGBEPDGP_02092 4.52e-201 dinB2 - - L ko:K03502 - ko00000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HGBEPDGP_02093 2.36e-44 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HGBEPDGP_02095 3.72e-58 - - - - - - - -
HGBEPDGP_02097 5.21e-26 - - - - - - - -
HGBEPDGP_02098 8.94e-13 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HGBEPDGP_02099 3.93e-117 yokH - - G - - - SMI1 / KNR4 family
HGBEPDGP_02100 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
HGBEPDGP_02101 8.66e-70 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
HGBEPDGP_02102 1.9e-173 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
HGBEPDGP_02103 1.24e-181 - - - J - - - FR47-like protein
HGBEPDGP_02104 3.09e-127 yobS - - K - - - Transcriptional regulator
HGBEPDGP_02105 3.16e-168 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HGBEPDGP_02106 6.32e-114 - - - K - - - Bacterial transcription activator, effector binding domain
HGBEPDGP_02107 1.97e-227 yobV - - K - - - WYL domain
HGBEPDGP_02108 6.07e-120 yobW - - - - - - -
HGBEPDGP_02109 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
HGBEPDGP_02110 3.28e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HGBEPDGP_02111 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
HGBEPDGP_02112 2.6e-185 - - - - - - - -
HGBEPDGP_02113 1.08e-121 yocC - - - - - - -
HGBEPDGP_02114 1.84e-136 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
HGBEPDGP_02115 6.62e-257 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
HGBEPDGP_02116 2.37e-250 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HGBEPDGP_02117 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGBEPDGP_02118 2.89e-175 yocH - - M - - - COG1388 FOG LysM repeat
HGBEPDGP_02119 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
HGBEPDGP_02120 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HGBEPDGP_02121 1.42e-107 yocK - - T - - - general stress protein
HGBEPDGP_02122 3.02e-70 yocL - - - - - - -
HGBEPDGP_02123 5.79e-43 - - - - - - - -
HGBEPDGP_02124 6.6e-115 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HGBEPDGP_02125 2.94e-55 yozN - - - - - - -
HGBEPDGP_02126 1.83e-49 yocN - - - - - - -
HGBEPDGP_02127 2.17e-74 yozO - - S - - - Bacterial PH domain
HGBEPDGP_02128 1.91e-42 yozC - - - - - - -
HGBEPDGP_02129 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HGBEPDGP_02130 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
HGBEPDGP_02131 6.49e-210 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
HGBEPDGP_02132 6.18e-300 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HGBEPDGP_02133 7.79e-213 yocS - - S ko:K03453 - ko00000 -transporter
HGBEPDGP_02134 3.02e-263 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HGBEPDGP_02135 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HGBEPDGP_02136 0.0 yojO - - P - - - Von Willebrand factor
HGBEPDGP_02137 1.33e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
HGBEPDGP_02138 6.01e-141 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HGBEPDGP_02139 3.72e-267 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
HGBEPDGP_02140 1.13e-293 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
HGBEPDGP_02141 2.49e-140 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HGBEPDGP_02143 8.38e-313 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
HGBEPDGP_02144 1.01e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HGBEPDGP_02145 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
HGBEPDGP_02146 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
HGBEPDGP_02147 1.07e-57 - - - - - - - -
HGBEPDGP_02148 2.84e-208 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
HGBEPDGP_02149 7.69e-100 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
HGBEPDGP_02150 5.59e-14 - - - - - - - -
HGBEPDGP_02151 1.86e-289 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
HGBEPDGP_02152 3.97e-84 iolK - - S - - - tautomerase
HGBEPDGP_02153 2.63e-73 yodB - - K - - - transcriptional
HGBEPDGP_02154 1.11e-139 yodC - - C - - - nitroreductase
HGBEPDGP_02155 8.86e-145 yahD - - S ko:K06999 - ko00000 Carboxylesterase
HGBEPDGP_02156 3.24e-221 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HGBEPDGP_02157 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
HGBEPDGP_02158 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HGBEPDGP_02159 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HGBEPDGP_02160 1.83e-167 yodH - - Q - - - Methyltransferase
HGBEPDGP_02161 2.93e-42 yodI - - - - - - -
HGBEPDGP_02162 1.33e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
HGBEPDGP_02163 1.19e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
HGBEPDGP_02164 2.08e-12 - - - - - - - -
HGBEPDGP_02165 1.17e-71 yodL - - S - - - YodL-like
HGBEPDGP_02166 4.02e-138 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
HGBEPDGP_02167 1.49e-33 yozD - - S - - - YozD-like protein
HGBEPDGP_02169 1.29e-159 yodN - - - - - - -
HGBEPDGP_02170 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
HGBEPDGP_02171 1.4e-62 yokU - - S - - - YokU-like protein, putative antitoxin
HGBEPDGP_02172 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
HGBEPDGP_02173 1.24e-195 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
HGBEPDGP_02174 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
HGBEPDGP_02175 4.49e-151 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HGBEPDGP_02176 3.27e-159 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HGBEPDGP_02177 2.34e-315 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HGBEPDGP_02179 2.4e-185 yiiD - - K ko:K06323 - ko00000 acetyltransferase
HGBEPDGP_02180 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
HGBEPDGP_02181 3.04e-59 cgeC - - - ko:K06321 - ko00000 -
HGBEPDGP_02182 1.12e-85 cgeA - - - ko:K06319 - ko00000 -
HGBEPDGP_02183 4.7e-237 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
HGBEPDGP_02184 4.66e-279 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
HGBEPDGP_02185 5.81e-158 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
HGBEPDGP_02186 2.04e-102 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
HGBEPDGP_02187 8.41e-134 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HGBEPDGP_02188 4.14e-94 ypoP - - K - - - transcriptional
HGBEPDGP_02189 2.86e-289 mepA - - V - - - MATE efflux family protein
HGBEPDGP_02190 2.13e-40 ypmT - - S - - - Uncharacterized ympT
HGBEPDGP_02191 1.95e-128 ypmS - - S - - - protein conserved in bacteria
HGBEPDGP_02192 1.28e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
HGBEPDGP_02193 3.23e-139 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HGBEPDGP_02194 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
HGBEPDGP_02195 1.73e-308 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HGBEPDGP_02196 1.4e-236 yplP - - K - - - Transcriptional regulator
HGBEPDGP_02197 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
HGBEPDGP_02198 8.12e-144 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HGBEPDGP_02199 9.58e-122 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HGBEPDGP_02200 9.52e-199 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HGBEPDGP_02201 1.8e-120 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
HGBEPDGP_02202 1.16e-146 ypjP - - S - - - YpjP-like protein
HGBEPDGP_02203 1.14e-182 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
HGBEPDGP_02204 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
HGBEPDGP_02205 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
HGBEPDGP_02206 8.52e-206 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
HGBEPDGP_02207 3.3e-138 yagB - - S ko:K06950 - ko00000 phosphohydrolase
HGBEPDGP_02208 2.58e-113 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
HGBEPDGP_02209 1.28e-226 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HGBEPDGP_02210 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HGBEPDGP_02211 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
HGBEPDGP_02212 1.17e-22 degR - - - - - - -
HGBEPDGP_02213 5.22e-41 - - - S - - - Protein of unknown function (DUF2564)
HGBEPDGP_02214 1.54e-37 ypeQ - - S - - - Zinc-finger
HGBEPDGP_02215 6.45e-173 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
HGBEPDGP_02216 3.27e-136 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HGBEPDGP_02217 7.64e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
HGBEPDGP_02218 5.23e-05 - - - - ko:K06429 - ko00000 -
HGBEPDGP_02219 2.26e-213 ypcP - - L - - - 5'3' exonuclease
HGBEPDGP_02220 1.08e-11 - - - - - - - -
HGBEPDGP_02221 4.07e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
HGBEPDGP_02222 0.0 ypbR - - S - - - Dynamin family
HGBEPDGP_02223 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
HGBEPDGP_02224 2.07e-262 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
HGBEPDGP_02225 3.51e-291 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
HGBEPDGP_02226 1.65e-128 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HGBEPDGP_02227 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HGBEPDGP_02228 4.09e-224 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HGBEPDGP_02229 1.47e-132 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
HGBEPDGP_02230 2.83e-237 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
HGBEPDGP_02231 4.51e-237 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
HGBEPDGP_02232 1.2e-202 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HGBEPDGP_02233 1.88e-175 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGBEPDGP_02234 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
HGBEPDGP_02236 2.84e-286 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HGBEPDGP_02237 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HGBEPDGP_02238 9.4e-128 ypsA - - S - - - Belongs to the UPF0398 family
HGBEPDGP_02239 9.82e-299 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
HGBEPDGP_02240 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HGBEPDGP_02241 7.43e-110 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
HGBEPDGP_02242 1.24e-94 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HGBEPDGP_02243 1.45e-66 yppG - - S - - - YppG-like protein
HGBEPDGP_02244 9.21e-11 - - - S - - - YppF-like protein
HGBEPDGP_02245 7.14e-11 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
HGBEPDGP_02248 3.44e-236 yppC - - S - - - Protein of unknown function (DUF2515)
HGBEPDGP_02249 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HGBEPDGP_02250 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HGBEPDGP_02251 1.17e-120 ypoC - - - - - - -
HGBEPDGP_02252 5.92e-157 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HGBEPDGP_02253 1.9e-164 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
HGBEPDGP_02254 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
HGBEPDGP_02255 4.37e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HGBEPDGP_02256 2.66e-102 ypmB - - S - - - protein conserved in bacteria
HGBEPDGP_02257 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
HGBEPDGP_02258 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
HGBEPDGP_02259 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HGBEPDGP_02260 6.39e-199 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HGBEPDGP_02261 4.85e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HGBEPDGP_02262 2.81e-233 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HGBEPDGP_02263 1.41e-283 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HGBEPDGP_02264 2.45e-267 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
HGBEPDGP_02265 1.89e-166 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
HGBEPDGP_02266 2.95e-92 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
HGBEPDGP_02267 8.04e-188 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HGBEPDGP_02268 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
HGBEPDGP_02269 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HGBEPDGP_02270 6.84e-183 ypjB - - S - - - sporulation protein
HGBEPDGP_02271 2.31e-125 ypjA - - S - - - membrane
HGBEPDGP_02272 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
HGBEPDGP_02273 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
HGBEPDGP_02274 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
HGBEPDGP_02275 4.56e-99 ypiF - - S - - - Protein of unknown function (DUF2487)
HGBEPDGP_02276 1.83e-129 ypiB - - S - - - Belongs to the UPF0302 family
HGBEPDGP_02277 8.74e-298 ypiA - - S - - - COG0457 FOG TPR repeat
HGBEPDGP_02278 4.03e-301 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HGBEPDGP_02279 2e-263 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
HGBEPDGP_02280 3.7e-258 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HGBEPDGP_02281 3.82e-186 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HGBEPDGP_02282 3.8e-294 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HGBEPDGP_02283 2.71e-151 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
HGBEPDGP_02284 4e-143 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
HGBEPDGP_02285 2.67e-200 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HGBEPDGP_02286 1.14e-15 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HGBEPDGP_02287 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HGBEPDGP_02288 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HGBEPDGP_02289 4.7e-262 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HGBEPDGP_02290 1.44e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HGBEPDGP_02291 2.13e-182 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
HGBEPDGP_02292 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HGBEPDGP_02293 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HGBEPDGP_02294 3.84e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HGBEPDGP_02295 8.72e-178 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HGBEPDGP_02296 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HGBEPDGP_02297 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
HGBEPDGP_02298 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HGBEPDGP_02299 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HGBEPDGP_02300 2.5e-175 yphF - - - - - - -
HGBEPDGP_02301 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
HGBEPDGP_02302 6.32e-231 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HGBEPDGP_02303 1.72e-315 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HGBEPDGP_02304 5.91e-38 ypzH - - - - - - -
HGBEPDGP_02305 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
HGBEPDGP_02306 3.87e-134 yphA - - - - - - -
HGBEPDGP_02307 5.6e-12 - - - S - - - YpzI-like protein
HGBEPDGP_02308 1.1e-233 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HGBEPDGP_02309 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HGBEPDGP_02310 3.91e-144 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HGBEPDGP_02311 2.48e-32 - - - S - - - Family of unknown function (DUF5359)
HGBEPDGP_02312 1.04e-140 ypfA - - M - - - Flagellar protein YcgR
HGBEPDGP_02313 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
HGBEPDGP_02314 1.1e-204 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
HGBEPDGP_02315 1.76e-153 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
HGBEPDGP_02316 4.25e-223 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
HGBEPDGP_02317 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HGBEPDGP_02318 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HGBEPDGP_02319 4.33e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
HGBEPDGP_02320 1.42e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
HGBEPDGP_02321 4.22e-139 ypbE - - M - - - Lysin motif
HGBEPDGP_02322 6.13e-129 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
HGBEPDGP_02323 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
HGBEPDGP_02324 5.67e-258 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
HGBEPDGP_02325 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
HGBEPDGP_02326 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HGBEPDGP_02327 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGBEPDGP_02328 3.37e-174 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HGBEPDGP_02329 1.49e-254 rsiX - - - - - - -
HGBEPDGP_02330 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HGBEPDGP_02331 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HGBEPDGP_02332 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGBEPDGP_02333 4.67e-279 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HGBEPDGP_02334 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
HGBEPDGP_02335 2.14e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HGBEPDGP_02336 1.81e-168 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HGBEPDGP_02337 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
HGBEPDGP_02338 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
HGBEPDGP_02339 1.13e-270 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HGBEPDGP_02340 2.92e-126 ypuI - - S - - - Protein of unknown function (DUF3907)
HGBEPDGP_02341 2e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HGBEPDGP_02342 3.82e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HGBEPDGP_02343 3.57e-120 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
HGBEPDGP_02344 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGBEPDGP_02345 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HGBEPDGP_02346 1.27e-291 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HGBEPDGP_02347 2.5e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
HGBEPDGP_02348 2.93e-260 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HGBEPDGP_02349 5.98e-72 ypuD - - - - - - -
HGBEPDGP_02350 1.18e-125 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HGBEPDGP_02351 4.14e-21 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
HGBEPDGP_02353 3.82e-09 - - - S - - - SNARE associated Golgi protein
HGBEPDGP_02355 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HGBEPDGP_02356 2.67e-193 ypuA - - S - - - Secreted protein
HGBEPDGP_02357 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HGBEPDGP_02358 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
HGBEPDGP_02359 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
HGBEPDGP_02360 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
HGBEPDGP_02361 6.02e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
HGBEPDGP_02362 5.52e-101 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
HGBEPDGP_02363 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
HGBEPDGP_02364 1.15e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
HGBEPDGP_02365 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGBEPDGP_02366 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HGBEPDGP_02367 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
HGBEPDGP_02368 5.82e-272 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HGBEPDGP_02369 8.04e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HGBEPDGP_02370 2.77e-293 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
HGBEPDGP_02371 1.59e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
HGBEPDGP_02372 2.25e-49 - - - S - - - Protein of unknown function (DUF4227)
HGBEPDGP_02373 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HGBEPDGP_02374 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HGBEPDGP_02375 3.73e-44 yqkK - - - - - - -
HGBEPDGP_02376 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
HGBEPDGP_02377 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
HGBEPDGP_02378 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
HGBEPDGP_02379 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
HGBEPDGP_02380 3.18e-77 ansR - - K - - - Transcriptional regulator
HGBEPDGP_02381 2.62e-283 yqxK - - L - - - DNA helicase
HGBEPDGP_02382 1.17e-119 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
HGBEPDGP_02383 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
HGBEPDGP_02384 8.88e-216 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
HGBEPDGP_02385 6.61e-26 yqkE - - S - - - Protein of unknown function (DUF3886)
HGBEPDGP_02386 4.29e-227 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
HGBEPDGP_02387 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
HGBEPDGP_02388 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
HGBEPDGP_02389 2.89e-251 yqkA - - K - - - GrpB protein
HGBEPDGP_02390 5.51e-79 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
HGBEPDGP_02391 5.46e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
HGBEPDGP_02392 1.87e-65 yqiX - - S - - - YolD-like protein
HGBEPDGP_02393 4.03e-304 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HGBEPDGP_02395 2.04e-289 yqjV - - G - - - Major Facilitator Superfamily
HGBEPDGP_02397 6.12e-92 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGBEPDGP_02398 6.6e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
HGBEPDGP_02399 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
HGBEPDGP_02400 1.39e-184 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HGBEPDGP_02401 3.14e-227 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HGBEPDGP_02402 9.98e-183 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HGBEPDGP_02403 0.0 rocB - - E - - - arginine degradation protein
HGBEPDGP_02404 4.94e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HGBEPDGP_02405 3.86e-188 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HGBEPDGP_02406 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HGBEPDGP_02407 7.66e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HGBEPDGP_02408 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HGBEPDGP_02409 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HGBEPDGP_02410 7.8e-301 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HGBEPDGP_02411 1.77e-32 yqzJ - - - - - - -
HGBEPDGP_02412 3.36e-184 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HGBEPDGP_02413 8.77e-184 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
HGBEPDGP_02414 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
HGBEPDGP_02415 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HGBEPDGP_02416 4.49e-93 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
HGBEPDGP_02418 2.41e-128 yqjB - - S - - - protein conserved in bacteria
HGBEPDGP_02419 1.55e-224 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
HGBEPDGP_02420 5.2e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HGBEPDGP_02421 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HGBEPDGP_02422 1.43e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HGBEPDGP_02423 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
HGBEPDGP_02424 1.72e-213 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HGBEPDGP_02425 6.23e-267 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
HGBEPDGP_02426 7.45e-194 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
HGBEPDGP_02427 3.77e-288 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HGBEPDGP_02428 1.98e-234 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HGBEPDGP_02429 1.92e-238 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HGBEPDGP_02430 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HGBEPDGP_02431 3.39e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
HGBEPDGP_02432 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HGBEPDGP_02433 1.18e-196 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
HGBEPDGP_02434 0.0 bkdR - - KT - - - Transcriptional regulator
HGBEPDGP_02435 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
HGBEPDGP_02436 7.23e-208 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HGBEPDGP_02437 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
HGBEPDGP_02438 2.63e-264 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HGBEPDGP_02439 1.65e-266 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
HGBEPDGP_02440 2.81e-198 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
HGBEPDGP_02441 2.32e-280 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HGBEPDGP_02442 3.39e-168 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HGBEPDGP_02443 2.7e-137 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
HGBEPDGP_02444 2.26e-37 - - - - - - - -
HGBEPDGP_02445 1.15e-272 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HGBEPDGP_02447 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HGBEPDGP_02448 1.26e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
HGBEPDGP_02449 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HGBEPDGP_02450 3.75e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HGBEPDGP_02451 1.77e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
HGBEPDGP_02452 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HGBEPDGP_02453 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HGBEPDGP_02454 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HGBEPDGP_02455 3.55e-312 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HGBEPDGP_02456 1.07e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HGBEPDGP_02457 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HGBEPDGP_02458 1.65e-88 yqhY - - S - - - protein conserved in bacteria
HGBEPDGP_02459 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HGBEPDGP_02460 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HGBEPDGP_02461 4.04e-134 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
HGBEPDGP_02462 2.43e-145 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
HGBEPDGP_02463 2.58e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
HGBEPDGP_02464 1.8e-255 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
HGBEPDGP_02465 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
HGBEPDGP_02466 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
HGBEPDGP_02467 5.69e-111 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
HGBEPDGP_02468 3.35e-216 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
HGBEPDGP_02469 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
HGBEPDGP_02470 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HGBEPDGP_02471 2.99e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
HGBEPDGP_02472 1.17e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
HGBEPDGP_02473 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
HGBEPDGP_02474 2.98e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
HGBEPDGP_02475 5.18e-81 yqhP - - - - - - -
HGBEPDGP_02476 1.21e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
HGBEPDGP_02477 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HGBEPDGP_02478 9.17e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HGBEPDGP_02479 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
HGBEPDGP_02480 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HGBEPDGP_02481 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HGBEPDGP_02482 1.11e-260 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
HGBEPDGP_02483 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
HGBEPDGP_02484 9.14e-197 yqhG - - S - - - Bacterial protein YqhG of unknown function
HGBEPDGP_02485 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
HGBEPDGP_02486 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
HGBEPDGP_02487 9e-182 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
HGBEPDGP_02488 4.27e-97 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
HGBEPDGP_02489 8e-156 yqxM - - - ko:K19433 - ko00000 -
HGBEPDGP_02490 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
HGBEPDGP_02491 3.33e-35 yqzE - - S - - - YqzE-like protein
HGBEPDGP_02492 3.24e-58 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
HGBEPDGP_02493 2.77e-44 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
HGBEPDGP_02494 3.45e-76 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
HGBEPDGP_02495 1.05e-88 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
HGBEPDGP_02496 3.09e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
HGBEPDGP_02497 2.14e-219 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
HGBEPDGP_02498 9.05e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HGBEPDGP_02500 3.8e-06 - - - S - - - Domain in cystathionine beta-synthase and other proteins.
HGBEPDGP_02501 1.51e-233 yqxL - - P - - - Mg2 transporter protein
HGBEPDGP_02502 2.86e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HGBEPDGP_02503 7.14e-192 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HGBEPDGP_02505 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
HGBEPDGP_02506 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
HGBEPDGP_02507 3.2e-157 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
HGBEPDGP_02508 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
HGBEPDGP_02509 7.34e-66 yqgV - - S - - - Thiamine-binding protein
HGBEPDGP_02510 2.69e-256 yqgU - - - - - - -
HGBEPDGP_02511 3.04e-283 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
HGBEPDGP_02512 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
HGBEPDGP_02513 2.81e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
HGBEPDGP_02514 9.15e-45 yqgQ - - S - - - Protein conserved in bacteria
HGBEPDGP_02515 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
HGBEPDGP_02516 3.38e-14 yqgO - - - - - - -
HGBEPDGP_02517 3.8e-135 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HGBEPDGP_02518 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HGBEPDGP_02519 2.81e-257 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
HGBEPDGP_02521 2.81e-67 yqzD - - - - - - -
HGBEPDGP_02522 1.09e-93 yqzC - - S - - - YceG-like family
HGBEPDGP_02523 1.57e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HGBEPDGP_02524 2.4e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HGBEPDGP_02525 5.26e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
HGBEPDGP_02526 1.43e-202 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HGBEPDGP_02527 2.61e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HGBEPDGP_02528 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
HGBEPDGP_02529 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
HGBEPDGP_02530 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
HGBEPDGP_02531 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
HGBEPDGP_02532 1.58e-167 yqgB - - S - - - Protein of unknown function (DUF1189)
HGBEPDGP_02533 1.64e-62 yqfZ - - M ko:K06417 - ko00000 LysM domain
HGBEPDGP_02534 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HGBEPDGP_02535 2.04e-81 yqfX - - S - - - membrane
HGBEPDGP_02536 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
HGBEPDGP_02537 2.47e-106 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
HGBEPDGP_02538 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HGBEPDGP_02539 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
HGBEPDGP_02540 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HGBEPDGP_02541 5.42e-311 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HGBEPDGP_02542 4.89e-58 yqfQ - - S - - - YqfQ-like protein
HGBEPDGP_02543 8.66e-227 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HGBEPDGP_02544 9.26e-270 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HGBEPDGP_02545 2.41e-150 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HGBEPDGP_02546 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
HGBEPDGP_02547 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HGBEPDGP_02548 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HGBEPDGP_02549 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
HGBEPDGP_02550 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HGBEPDGP_02551 3.29e-144 ccpN - - K - - - CBS domain
HGBEPDGP_02552 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
HGBEPDGP_02553 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
HGBEPDGP_02554 5.26e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HGBEPDGP_02555 5.29e-27 - - - S - - - YqzL-like protein
HGBEPDGP_02556 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HGBEPDGP_02557 6.71e-93 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HGBEPDGP_02558 1.42e-81 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
HGBEPDGP_02559 8.68e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HGBEPDGP_02560 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
HGBEPDGP_02562 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
HGBEPDGP_02563 1.04e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
HGBEPDGP_02564 2.07e-60 yqfC - - S - - - sporulation protein YqfC
HGBEPDGP_02565 3.13e-79 yqfB - - - - - - -
HGBEPDGP_02566 8.78e-192 yqfA - - S - - - UPF0365 protein
HGBEPDGP_02567 1.32e-290 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
HGBEPDGP_02568 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
HGBEPDGP_02569 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HGBEPDGP_02570 2.04e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
HGBEPDGP_02571 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
HGBEPDGP_02572 6.85e-179 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HGBEPDGP_02573 9.34e-225 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
HGBEPDGP_02574 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HGBEPDGP_02575 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HGBEPDGP_02576 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HGBEPDGP_02577 1.65e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HGBEPDGP_02578 2.9e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
HGBEPDGP_02579 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HGBEPDGP_02580 6.28e-73 yqxA - - S - - - Protein of unknown function (DUF3679)
HGBEPDGP_02581 2.73e-283 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
HGBEPDGP_02582 3.42e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HGBEPDGP_02583 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HGBEPDGP_02584 1.16e-243 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HGBEPDGP_02585 2.36e-22 - - - S - - - YqzM-like protein
HGBEPDGP_02586 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HGBEPDGP_02587 5.39e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
HGBEPDGP_02588 6.65e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
HGBEPDGP_02589 2.69e-189 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HGBEPDGP_02590 9.8e-179 yqeM - - Q - - - Methyltransferase
HGBEPDGP_02591 9.76e-82 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HGBEPDGP_02592 4.81e-133 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
HGBEPDGP_02593 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HGBEPDGP_02594 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
HGBEPDGP_02595 8.44e-201 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HGBEPDGP_02596 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HGBEPDGP_02597 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
HGBEPDGP_02599 6.41e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
HGBEPDGP_02600 4.44e-172 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
HGBEPDGP_02601 9.36e-135 yqeD - - S - - - SNARE associated Golgi protein
HGBEPDGP_02602 1.29e-23 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
HGBEPDGP_02603 3e-169 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
HGBEPDGP_02604 1.56e-169 - - - - - - - -
HGBEPDGP_02605 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
HGBEPDGP_02606 1.1e-72 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGBEPDGP_02607 0.0 - - - L ko:K06400 - ko00000 Recombinase
HGBEPDGP_02608 9.82e-101 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Catalyzes the reduction of arsenate As(V) to arsenite As(III)
HGBEPDGP_02609 7.13e-233 arsB - - P ko:K03325 - ko00000,ko02000 Arsenic resistance protein
HGBEPDGP_02610 2.56e-104 cadI 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGBEPDGP_02611 1.53e-72 arsR - - K ko:K03892 - ko00000,ko03000 ArsR family transcriptional regulator
HGBEPDGP_02612 2.08e-197 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
HGBEPDGP_02613 1.37e-30 - - - S - - - YtkA-like
HGBEPDGP_02614 9e-62 - - - S - - - PepSY-associated TM region
HGBEPDGP_02615 1.69e-142 - - - S - - - PepSY-associated TM region
HGBEPDGP_02616 3.16e-81 - - - K - - - BetI-type transcriptional repressor, C-terminal
HGBEPDGP_02617 1.78e-175 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
HGBEPDGP_02618 1.77e-61 - - - - - - - -
HGBEPDGP_02619 1.51e-54 - - - S - - - Protein of unknown function (DUF3992)
HGBEPDGP_02620 4.35e-53 - - - S - - - Spore coat protein Z
HGBEPDGP_02621 1.14e-117 - - - S - - - Tetratricopeptide repeat
HGBEPDGP_02624 0.0 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
HGBEPDGP_02625 1.37e-135 - - - S ko:K21492 - ko00000,ko02048 Suppressor of fused protein (SUFU)
HGBEPDGP_02627 5.4e-80 - - - - - - - -
HGBEPDGP_02629 9.72e-187 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
HGBEPDGP_02630 8.36e-89 - - - S - - - Bacteriophage holin family
HGBEPDGP_02631 2.45e-213 xepA - - - - - - -
HGBEPDGP_02632 9.34e-33 - - - - - - - -
HGBEPDGP_02633 1.01e-73 xkdW - - S - - - XkdW protein
HGBEPDGP_02634 2.91e-283 - - - - - - - -
HGBEPDGP_02635 3e-54 - - - - - - - -
HGBEPDGP_02636 4.58e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
HGBEPDGP_02637 1.31e-245 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HGBEPDGP_02638 1.14e-91 xkdS - - S - - - Protein of unknown function (DUF2634)
HGBEPDGP_02639 6.68e-52 xkdR - - S - - - Protein of unknown function (DUF2577)
HGBEPDGP_02640 1.02e-231 xkdQ - - G - - - NLP P60 protein
HGBEPDGP_02641 6.56e-156 xkdP - - S - - - Lysin motif
HGBEPDGP_02642 0.0 xkdO - - L - - - Transglycosylase SLT domain
HGBEPDGP_02643 1.27e-89 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
HGBEPDGP_02644 1.21e-98 xkdM - - S - - - Phage tail tube protein
HGBEPDGP_02645 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
HGBEPDGP_02646 1.21e-34 - - - - - - - -
HGBEPDGP_02647 8.94e-100 yqbJ - - - - - - -
HGBEPDGP_02648 7.57e-114 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
HGBEPDGP_02649 2.38e-83 yqbH - - S - - - Domain of unknown function (DUF3599)
HGBEPDGP_02650 2.89e-87 - - - S - - - Protein of unknown function (DUF3199)
HGBEPDGP_02651 5.19e-61 - - - S - - - YqbF, hypothetical protein domain
HGBEPDGP_02652 4.37e-214 xkdG - - S - - - Phage capsid family
HGBEPDGP_02653 3.46e-157 yqbD - - L - - - Putative phage serine protease XkdF
HGBEPDGP_02655 1.37e-182 - - - S - - - Phage Mu protein F like protein
HGBEPDGP_02656 0.0 yqbA - - S - - - portal protein
HGBEPDGP_02657 2.69e-312 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
HGBEPDGP_02658 7.73e-147 yqaS - - L - - - DNA packaging
HGBEPDGP_02660 6.42e-96 yqaQ - - L - - - Transposase
HGBEPDGP_02663 3.18e-42 yqaO - - S - - - Phage-like element PBSX protein XtrA
HGBEPDGP_02664 2.58e-93 rusA - - L - - - Endodeoxyribonuclease RusA
HGBEPDGP_02666 5.04e-207 yqaM - - L - - - IstB-like ATP binding protein
HGBEPDGP_02667 5.29e-156 yqaL - - L - - - DnaD domain protein
HGBEPDGP_02668 2.79e-192 recT - - L ko:K07455 - ko00000,ko03400 RecT family
HGBEPDGP_02669 3.18e-213 yqaJ - - L - - - YqaJ-like viral recombinase domain
HGBEPDGP_02673 1.04e-133 - - - - - - - -
HGBEPDGP_02675 3.43e-49 - - - K - - - Helix-turn-helix XRE-family like proteins
HGBEPDGP_02676 1.25e-74 - - - K - - - sequence-specific DNA binding
HGBEPDGP_02678 4.16e-130 yqaC - - F - - - adenylate kinase activity
HGBEPDGP_02679 2.62e-121 xkdA - - E - - - IrrE N-terminal-like domain
HGBEPDGP_02680 4.46e-79 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGBEPDGP_02681 7.32e-306 yrkQ - - T - - - Histidine kinase
HGBEPDGP_02682 1.24e-164 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
HGBEPDGP_02683 2.16e-282 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
HGBEPDGP_02684 6.33e-133 yrkN - - K - - - Acetyltransferase (GNAT) family
HGBEPDGP_02685 5.71e-126 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
HGBEPDGP_02686 3.13e-104 - - - S - - - Protein of unknown function with HXXEE motif
HGBEPDGP_02687 1.9e-149 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
HGBEPDGP_02688 3.2e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
HGBEPDGP_02689 2.07e-263 yrkH - - P - - - Rhodanese Homology Domain
HGBEPDGP_02690 2.28e-126 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
HGBEPDGP_02691 7.44e-86 yrkE - - O - - - DsrE/DsrF/DrsH-like family
HGBEPDGP_02692 4.38e-52 yrkD - - S - - - protein conserved in bacteria
HGBEPDGP_02693 6.08e-136 yrkC - - G - - - Cupin domain
HGBEPDGP_02694 1.24e-194 bltR - - K - - - helix_turn_helix, mercury resistance
HGBEPDGP_02695 7.59e-269 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
HGBEPDGP_02696 7.23e-107 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
HGBEPDGP_02697 1.02e-297 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HGBEPDGP_02698 2.45e-23 - - - S - - - YrzO-like protein
HGBEPDGP_02699 2.84e-215 yrdR - - EG - - - EamA-like transporter family
HGBEPDGP_02700 1.64e-202 - - - K - - - Transcriptional regulator
HGBEPDGP_02701 7.41e-255 trkA - - P ko:K07222 - ko00000 Oxidoreductase
HGBEPDGP_02702 2e-211 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
HGBEPDGP_02703 1.44e-86 yodA - - S - - - tautomerase
HGBEPDGP_02704 6.6e-201 - - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
HGBEPDGP_02705 5.01e-41 - - - C - - - COG2041 Sulfite oxidase and related enzymes
HGBEPDGP_02706 1.01e-291 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HGBEPDGP_02707 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
HGBEPDGP_02708 9.34e-176 azlC - - E - - - AzlC protein
HGBEPDGP_02709 4.13e-104 bkdR - - K - - - helix_turn_helix ASNC type
HGBEPDGP_02710 1.76e-22 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
HGBEPDGP_02711 5.86e-294 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HGBEPDGP_02712 1.01e-128 yrdC - - Q - - - Isochorismatase family
HGBEPDGP_02713 2.99e-71 - - - S - - - Protein of unknown function (DUF2568)
HGBEPDGP_02714 1.17e-117 yrdA - - S - - - DinB family
HGBEPDGP_02715 5.77e-210 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
HGBEPDGP_02716 5.15e-247 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HGBEPDGP_02717 1.39e-187 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HGBEPDGP_02718 4.62e-160 yrpD - - S - - - Domain of unknown function, YrpD
HGBEPDGP_02719 6.71e-128 - - - K ko:K05799 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
HGBEPDGP_02721 4.11e-268 - - - P - - - Major Facilitator Superfamily
HGBEPDGP_02722 6.21e-148 - - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGBEPDGP_02723 1.02e-192 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transketolase, pyrimidine binding domain
HGBEPDGP_02724 4.98e-172 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 COG3959 Transketolase, N-terminal subunit
HGBEPDGP_02725 3.1e-126 - - - S - - - Flavin reductase like domain
HGBEPDGP_02726 1.12e-156 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
HGBEPDGP_02727 1.62e-63 - - - S - - - YjbR
HGBEPDGP_02728 7.31e-167 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HGBEPDGP_02729 3.99e-118 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HGBEPDGP_02730 5.96e-240 yrpG - - C - - - Aldo/keto reductase family
HGBEPDGP_02731 2.16e-285 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
HGBEPDGP_02732 2.97e-210 yraN - - K - - - Transcriptional regulator
HGBEPDGP_02733 1.71e-262 yraM - - S - - - PrpF protein
HGBEPDGP_02734 9.5e-201 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HGBEPDGP_02735 6.15e-57 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGBEPDGP_02736 2.33e-194 - - - S - - - Alpha beta hydrolase
HGBEPDGP_02737 6.61e-80 - - - T - - - sh3 domain protein
HGBEPDGP_02738 2.92e-81 - - - T - - - sh3 domain protein
HGBEPDGP_02740 5.45e-86 - - - E - - - Glyoxalase-like domain
HGBEPDGP_02741 1.2e-49 yraG - - - ko:K06440 - ko00000 -
HGBEPDGP_02742 9.61e-84 yraF - - M - - - Spore coat protein
HGBEPDGP_02743 9.1e-284 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HGBEPDGP_02744 6.11e-36 yraE - - - ko:K06440 - ko00000 -
HGBEPDGP_02745 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
HGBEPDGP_02746 3.7e-67 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
HGBEPDGP_02747 3.95e-252 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
HGBEPDGP_02748 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
HGBEPDGP_02749 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
HGBEPDGP_02750 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HGBEPDGP_02751 6.11e-168 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HGBEPDGP_02752 8.91e-106 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
HGBEPDGP_02753 4.41e-96 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HGBEPDGP_02754 0.0 levR - - K - - - PTS system fructose IIA component
HGBEPDGP_02755 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
HGBEPDGP_02756 9.6e-114 yrhP - - E - - - LysE type translocator
HGBEPDGP_02757 2.81e-192 yrhO - - K - - - Archaeal transcriptional regulator TrmB
HGBEPDGP_02758 1.65e-112 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HGBEPDGP_02759 2.12e-192 rsiV - - S - - - Protein of unknown function (DUF3298)
HGBEPDGP_02760 0.0 oatA - - I - - - Acyltransferase family
HGBEPDGP_02761 6.3e-61 yrhK - - S - - - YrhK-like protein
HGBEPDGP_02762 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
HGBEPDGP_02763 2.26e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
HGBEPDGP_02764 7.42e-125 yrhH - - Q - - - methyltransferase
HGBEPDGP_02765 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
HGBEPDGP_02767 1.38e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
HGBEPDGP_02768 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
HGBEPDGP_02769 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
HGBEPDGP_02770 4.97e-102 yrhD - - S - - - Protein of unknown function (DUF1641)
HGBEPDGP_02771 6.93e-49 yrhC - - S - - - YrhC-like protein
HGBEPDGP_02772 1.42e-267 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HGBEPDGP_02773 9.59e-216 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
HGBEPDGP_02774 1.97e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HGBEPDGP_02775 2.42e-153 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
HGBEPDGP_02776 3.47e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
HGBEPDGP_02777 1.42e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
HGBEPDGP_02778 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
HGBEPDGP_02779 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HGBEPDGP_02780 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
HGBEPDGP_02781 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
HGBEPDGP_02782 7.67e-223 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
HGBEPDGP_02783 1.4e-154 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
HGBEPDGP_02784 7.19e-240 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HGBEPDGP_02785 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
HGBEPDGP_02786 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HGBEPDGP_02787 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
HGBEPDGP_02788 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HGBEPDGP_02789 8.81e-242 yrrI - - S - - - AI-2E family transporter
HGBEPDGP_02790 1.89e-169 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HGBEPDGP_02791 1.28e-187 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HGBEPDGP_02792 6.53e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HGBEPDGP_02793 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HGBEPDGP_02794 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
HGBEPDGP_02795 8.4e-42 yrzR - - - - - - -
HGBEPDGP_02796 3.39e-106 yrrD - - S - - - protein conserved in bacteria
HGBEPDGP_02797 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HGBEPDGP_02798 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
HGBEPDGP_02799 1.19e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HGBEPDGP_02800 1.87e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HGBEPDGP_02801 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
HGBEPDGP_02802 2.44e-303 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HGBEPDGP_02803 2.29e-176 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HGBEPDGP_02804 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HGBEPDGP_02805 1.27e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HGBEPDGP_02807 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
HGBEPDGP_02808 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HGBEPDGP_02809 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HGBEPDGP_02810 8.47e-117 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HGBEPDGP_02811 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HGBEPDGP_02812 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
HGBEPDGP_02813 3.1e-112 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
HGBEPDGP_02814 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HGBEPDGP_02815 5.53e-65 yrzD - - S - - - Post-transcriptional regulator
HGBEPDGP_02816 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HGBEPDGP_02817 5.83e-143 yrbG - - S - - - membrane
HGBEPDGP_02818 2.95e-96 yrzE - - S - - - Protein of unknown function (DUF3792)
HGBEPDGP_02819 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
HGBEPDGP_02820 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HGBEPDGP_02821 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HGBEPDGP_02822 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
HGBEPDGP_02823 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HGBEPDGP_02824 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HGBEPDGP_02825 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
HGBEPDGP_02826 0.0 csbX - - EGP - - - the major facilitator superfamily
HGBEPDGP_02827 7.93e-248 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
HGBEPDGP_02828 2.32e-152 yrzF - - T - - - serine threonine protein kinase
HGBEPDGP_02830 7.31e-67 - - - S - - - Family of unknown function (DUF5412)
HGBEPDGP_02832 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
HGBEPDGP_02833 8.63e-165 yebC - - K - - - transcriptional regulatory protein
HGBEPDGP_02834 2.08e-69 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HGBEPDGP_02835 4.02e-216 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
HGBEPDGP_02836 7.94e-273 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HGBEPDGP_02837 5.07e-202 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
HGBEPDGP_02838 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
HGBEPDGP_02839 3.35e-290 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HGBEPDGP_02840 5.86e-122 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
HGBEPDGP_02841 4.99e-209 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
HGBEPDGP_02842 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
HGBEPDGP_02843 1.6e-307 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HGBEPDGP_02844 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
HGBEPDGP_02845 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HGBEPDGP_02846 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
HGBEPDGP_02847 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HGBEPDGP_02848 3.74e-208 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
HGBEPDGP_02849 5.24e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
HGBEPDGP_02850 2.91e-186 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
HGBEPDGP_02851 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HGBEPDGP_02852 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
HGBEPDGP_02853 7.78e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HGBEPDGP_02854 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
HGBEPDGP_02855 1.97e-161 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
HGBEPDGP_02856 1.73e-132 maf - - D ko:K06287 - ko00000 septum formation protein Maf
HGBEPDGP_02857 3.36e-208 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
HGBEPDGP_02858 4.61e-107 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HGBEPDGP_02859 1.55e-315 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HGBEPDGP_02860 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HGBEPDGP_02861 1.53e-35 - - - - - - - -
HGBEPDGP_02862 1.96e-251 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HGBEPDGP_02863 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
HGBEPDGP_02864 1.05e-313 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
HGBEPDGP_02865 1.51e-232 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
HGBEPDGP_02866 2.49e-184 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
HGBEPDGP_02867 2.19e-220 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HGBEPDGP_02868 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
HGBEPDGP_02869 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HGBEPDGP_02870 8.23e-117 ysxD - - - - - - -
HGBEPDGP_02871 7.96e-118 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HGBEPDGP_02872 4.88e-06 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HGBEPDGP_02873 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HGBEPDGP_02874 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
HGBEPDGP_02875 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HGBEPDGP_02876 8.87e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HGBEPDGP_02877 1.3e-238 ysoA - - H - - - Tetratricopeptide repeat
HGBEPDGP_02878 1.04e-147 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HGBEPDGP_02879 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HGBEPDGP_02880 1.06e-255 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HGBEPDGP_02881 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HGBEPDGP_02882 3.91e-244 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HGBEPDGP_02883 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
HGBEPDGP_02884 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
HGBEPDGP_02886 3.73e-104 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
HGBEPDGP_02887 1.94e-180 ysnF - - S - - - protein conserved in bacteria
HGBEPDGP_02889 2.34e-118 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
HGBEPDGP_02890 3.05e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HGBEPDGP_02891 2.04e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HGBEPDGP_02892 8.03e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
HGBEPDGP_02893 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HGBEPDGP_02894 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
HGBEPDGP_02895 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
HGBEPDGP_02896 1.79e-100 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
HGBEPDGP_02897 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
HGBEPDGP_02898 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
HGBEPDGP_02899 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
HGBEPDGP_02900 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
HGBEPDGP_02901 3.96e-275 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HGBEPDGP_02902 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HGBEPDGP_02903 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HGBEPDGP_02904 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
HGBEPDGP_02906 3.02e-228 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
HGBEPDGP_02907 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
HGBEPDGP_02908 2.2e-176 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
HGBEPDGP_02909 1.21e-130 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
HGBEPDGP_02910 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HGBEPDGP_02911 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
HGBEPDGP_02912 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HGBEPDGP_02913 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
HGBEPDGP_02914 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
HGBEPDGP_02915 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HGBEPDGP_02916 2.96e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HGBEPDGP_02917 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HGBEPDGP_02918 1.81e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HGBEPDGP_02919 8.97e-171 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HGBEPDGP_02920 7.54e-44 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
HGBEPDGP_02921 4.34e-261 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
HGBEPDGP_02922 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
HGBEPDGP_02923 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
HGBEPDGP_02924 1.79e-69 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
HGBEPDGP_02925 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
HGBEPDGP_02926 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
HGBEPDGP_02927 4.28e-190 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
HGBEPDGP_02928 6.77e-219 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
HGBEPDGP_02929 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
HGBEPDGP_02930 1.07e-281 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HGBEPDGP_02931 6.06e-187 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
HGBEPDGP_02932 1.99e-169 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HGBEPDGP_02933 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
HGBEPDGP_02934 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
HGBEPDGP_02935 9.92e-242 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
HGBEPDGP_02936 2.93e-260 ysdC - - G - - - COG1363 Cellulase M and related proteins
HGBEPDGP_02937 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
HGBEPDGP_02938 1.27e-59 ysdA - - S - - - Membrane
HGBEPDGP_02939 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HGBEPDGP_02940 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HGBEPDGP_02941 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HGBEPDGP_02943 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HGBEPDGP_02944 2.08e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HGBEPDGP_02945 3.39e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
HGBEPDGP_02946 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HGBEPDGP_02947 1.2e-190 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
HGBEPDGP_02948 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HGBEPDGP_02949 5.98e-206 ytxC - - S - - - YtxC-like family
HGBEPDGP_02950 9.77e-144 ytxB - - S - - - SNARE associated Golgi protein
HGBEPDGP_02951 1.22e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
HGBEPDGP_02952 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
HGBEPDGP_02953 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HGBEPDGP_02954 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HGBEPDGP_02955 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HGBEPDGP_02956 9.85e-88 ytcD - - K - - - Transcriptional regulator
HGBEPDGP_02957 1.12e-254 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
HGBEPDGP_02958 4.54e-205 ytbE - - S - - - reductase
HGBEPDGP_02959 2.82e-126 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HGBEPDGP_02960 5.63e-137 ytaF - - P - - - Probably functions as a manganese efflux pump
HGBEPDGP_02961 3.88e-200 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HGBEPDGP_02962 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HGBEPDGP_02963 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
HGBEPDGP_02964 3.27e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGBEPDGP_02965 1.04e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
HGBEPDGP_02966 9.27e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
HGBEPDGP_02967 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HGBEPDGP_02968 9.38e-95 ytwI - - S - - - membrane
HGBEPDGP_02969 6.42e-244 ytvI - - S - - - sporulation integral membrane protein YtvI
HGBEPDGP_02970 4.68e-82 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
HGBEPDGP_02971 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
HGBEPDGP_02972 4.65e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HGBEPDGP_02973 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HGBEPDGP_02974 2.17e-208 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HGBEPDGP_02975 8.53e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
HGBEPDGP_02976 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HGBEPDGP_02977 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
HGBEPDGP_02978 5.12e-112 ytrI - - - - - - -
HGBEPDGP_02979 1.15e-39 - - - - - - - -
HGBEPDGP_02980 1.02e-229 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
HGBEPDGP_02981 2.15e-63 ytpI - - S - - - YtpI-like protein
HGBEPDGP_02982 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
HGBEPDGP_02983 6.14e-204 ytnM - - S ko:K07090 - ko00000 membrane transporter protein
HGBEPDGP_02984 1.58e-301 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
HGBEPDGP_02985 2.31e-164 - 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin kinase
HGBEPDGP_02986 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGBEPDGP_02987 1.24e-61 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
HGBEPDGP_02988 6.9e-234 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGBEPDGP_02989 5.43e-182 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HGBEPDGP_02990 7.89e-154 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGBEPDGP_02991 1.66e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGBEPDGP_02992 4.49e-191 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
HGBEPDGP_02993 7.48e-194 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
HGBEPDGP_02994 8.39e-130 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HGBEPDGP_02995 1.37e-220 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
HGBEPDGP_02996 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
HGBEPDGP_02997 1.98e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGBEPDGP_02999 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
HGBEPDGP_03000 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HGBEPDGP_03001 3.31e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
HGBEPDGP_03002 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HGBEPDGP_03003 3.78e-224 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
HGBEPDGP_03004 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HGBEPDGP_03005 1.06e-94 ytfJ - - S - - - Sporulation protein YtfJ
HGBEPDGP_03006 8.34e-149 ytfI - - S - - - Protein of unknown function (DUF2953)
HGBEPDGP_03007 4.08e-112 yteJ - - S - - - RDD family
HGBEPDGP_03008 2.79e-229 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
HGBEPDGP_03009 2.92e-190 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HGBEPDGP_03010 0.0 ytcJ - - S - - - amidohydrolase
HGBEPDGP_03011 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HGBEPDGP_03012 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
HGBEPDGP_03013 6.26e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HGBEPDGP_03014 1.07e-263 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HGBEPDGP_03015 8.23e-305 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HGBEPDGP_03016 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HGBEPDGP_03017 3.73e-198 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HGBEPDGP_03018 1.2e-141 yttP - - K - - - Transcriptional regulator
HGBEPDGP_03019 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
HGBEPDGP_03020 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
HGBEPDGP_03021 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HGBEPDGP_03023 1.85e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HGBEPDGP_03024 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HGBEPDGP_03025 2.84e-155 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HGBEPDGP_03026 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
HGBEPDGP_03027 2.65e-292 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
HGBEPDGP_03028 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
HGBEPDGP_03029 6.84e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
HGBEPDGP_03030 4.86e-234 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
HGBEPDGP_03031 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HGBEPDGP_03032 6.39e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
HGBEPDGP_03033 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
HGBEPDGP_03034 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HGBEPDGP_03035 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HGBEPDGP_03036 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HGBEPDGP_03037 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HGBEPDGP_03038 2.06e-191 ytpQ - - S - - - Belongs to the UPF0354 family
HGBEPDGP_03039 3.17e-75 ytpP - - CO - - - Thioredoxin
HGBEPDGP_03040 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
HGBEPDGP_03041 3.71e-261 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
HGBEPDGP_03042 1.17e-67 ytzB - - S - - - small secreted protein
HGBEPDGP_03043 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
HGBEPDGP_03044 5.09e-192 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HGBEPDGP_03045 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HGBEPDGP_03046 9.51e-61 ytzH - - S - - - YtzH-like protein
HGBEPDGP_03047 3.02e-192 ytmP - - M - - - Phosphotransferase
HGBEPDGP_03048 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HGBEPDGP_03049 9.05e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
HGBEPDGP_03050 4.04e-211 ytlQ - - - - - - -
HGBEPDGP_03051 4.29e-130 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HGBEPDGP_03052 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HGBEPDGP_03053 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
HGBEPDGP_03054 2.35e-286 pbuO - - S ko:K06901 - ko00000,ko02000 permease
HGBEPDGP_03055 3.51e-255 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
HGBEPDGP_03056 5.66e-168 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HGBEPDGP_03057 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
HGBEPDGP_03058 7.43e-170 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HGBEPDGP_03059 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HGBEPDGP_03060 4.04e-293 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
HGBEPDGP_03061 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
HGBEPDGP_03062 2.14e-36 yteV - - S - - - Sporulation protein Cse60
HGBEPDGP_03063 3.81e-150 yteU - - S - - - Integral membrane protein
HGBEPDGP_03064 0.0 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
HGBEPDGP_03065 6.78e-94 yteS - - G - - - transport
HGBEPDGP_03066 1.88e-275 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HGBEPDGP_03067 1.31e-220 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
HGBEPDGP_03068 0.0 ytdP - - K - - - Transcriptional regulator
HGBEPDGP_03069 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
HGBEPDGP_03070 1.02e-191 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
HGBEPDGP_03071 9.01e-178 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
HGBEPDGP_03072 1.75e-276 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HGBEPDGP_03073 1.86e-243 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HGBEPDGP_03074 2.57e-157 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HGBEPDGP_03075 1.82e-275 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HGBEPDGP_03076 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HGBEPDGP_03077 3.88e-180 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HGBEPDGP_03078 1.13e-219 - - - S - - - Acetyl xylan esterase (AXE1)
HGBEPDGP_03079 1.31e-243 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HGBEPDGP_03080 7.39e-312 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HGBEPDGP_03081 1.66e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HGBEPDGP_03082 7.65e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
HGBEPDGP_03083 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
HGBEPDGP_03084 7.08e-68 ytwF - - P - - - Sulfurtransferase
HGBEPDGP_03085 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HGBEPDGP_03086 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
HGBEPDGP_03087 3.14e-182 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HGBEPDGP_03088 1.21e-268 yttB - - EGP - - - Major facilitator superfamily
HGBEPDGP_03089 5.75e-78 yttA - - S - - - Pfam Transposase IS66
HGBEPDGP_03090 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
HGBEPDGP_03091 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
HGBEPDGP_03092 4.53e-239 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
HGBEPDGP_03093 2.07e-166 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGBEPDGP_03094 6.91e-297 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
HGBEPDGP_03095 1.02e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HGBEPDGP_03096 1.63e-163 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
HGBEPDGP_03097 5.22e-187 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HGBEPDGP_03098 1.4e-205 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HGBEPDGP_03099 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
HGBEPDGP_03101 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
HGBEPDGP_03102 2.35e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
HGBEPDGP_03103 1.59e-135 ytqB - - J - - - Putative rRNA methylase
HGBEPDGP_03104 2.29e-274 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
HGBEPDGP_03105 2.33e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
HGBEPDGP_03106 8.35e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HGBEPDGP_03107 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HGBEPDGP_03108 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HGBEPDGP_03109 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HGBEPDGP_03110 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HGBEPDGP_03111 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
HGBEPDGP_03112 3.86e-190 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HGBEPDGP_03113 4.22e-237 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HGBEPDGP_03114 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HGBEPDGP_03115 1.09e-182 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HGBEPDGP_03116 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
HGBEPDGP_03117 1.59e-81 ytkC - - S - - - Bacteriophage holin family
HGBEPDGP_03118 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HGBEPDGP_03120 5.58e-94 ytkA - - S - - - YtkA-like
HGBEPDGP_03121 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HGBEPDGP_03122 8.96e-134 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
HGBEPDGP_03123 1.44e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HGBEPDGP_03124 1.03e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
HGBEPDGP_03125 6.96e-240 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HGBEPDGP_03126 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
HGBEPDGP_03127 2.65e-191 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HGBEPDGP_03128 5.24e-296 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HGBEPDGP_03129 6.12e-179 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HGBEPDGP_03130 9.26e-218 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HGBEPDGP_03131 2.88e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HGBEPDGP_03132 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HGBEPDGP_03133 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HGBEPDGP_03134 1.29e-192 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HGBEPDGP_03135 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HGBEPDGP_03136 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
HGBEPDGP_03137 7.13e-168 yteA - - T - - - COG1734 DnaK suppressor protein
HGBEPDGP_03138 2.82e-195 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
HGBEPDGP_03139 1.6e-307 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HGBEPDGP_03140 1.23e-227 ytcB - - M - - - NAD-dependent epimerase dehydratase
HGBEPDGP_03141 5.88e-297 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
HGBEPDGP_03143 2.82e-262 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
HGBEPDGP_03144 1.01e-275 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
HGBEPDGP_03145 1.29e-260 cotI - - S ko:K06331 - ko00000 Spore coat protein
HGBEPDGP_03146 1.9e-99 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
HGBEPDGP_03147 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HGBEPDGP_03148 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
HGBEPDGP_03149 5.28e-238 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
HGBEPDGP_03150 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HGBEPDGP_03151 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HGBEPDGP_03173 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HGBEPDGP_03174 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
HGBEPDGP_03175 1.2e-122 - - - M - - - FR47-like protein
HGBEPDGP_03176 4.54e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
HGBEPDGP_03177 4.82e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
HGBEPDGP_03178 1.95e-109 yuaE - - S - - - DinB superfamily
HGBEPDGP_03179 8.58e-139 yuaD - - - - - - -
HGBEPDGP_03180 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
HGBEPDGP_03181 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HGBEPDGP_03182 3.53e-123 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
HGBEPDGP_03183 5.83e-118 yuaB - - - - - - -
HGBEPDGP_03184 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
HGBEPDGP_03185 1.07e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
HGBEPDGP_03186 3.31e-52 yubF - - S - - - yiaA/B two helix domain
HGBEPDGP_03187 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HGBEPDGP_03188 0.0 yubD - - P - - - Major Facilitator Superfamily
HGBEPDGP_03189 1.61e-112 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
HGBEPDGP_03191 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HGBEPDGP_03192 7.34e-254 yubA - - S - - - transporter activity
HGBEPDGP_03193 9.11e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
HGBEPDGP_03194 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
HGBEPDGP_03195 2.02e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
HGBEPDGP_03196 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HGBEPDGP_03197 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HGBEPDGP_03198 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
HGBEPDGP_03199 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HGBEPDGP_03200 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HGBEPDGP_03201 1.31e-294 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HGBEPDGP_03202 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HGBEPDGP_03203 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
HGBEPDGP_03204 1.44e-47 - - - - - - - -
HGBEPDGP_03205 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
HGBEPDGP_03206 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
HGBEPDGP_03207 1.03e-299 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HGBEPDGP_03208 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
HGBEPDGP_03209 1.58e-50 - - - - - - - -
HGBEPDGP_03210 2.12e-70 mstX - - S - - - Membrane-integrating protein Mistic
HGBEPDGP_03211 1.45e-232 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
HGBEPDGP_03212 9.97e-94 yugN - - S - - - YugN-like family
HGBEPDGP_03214 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HGBEPDGP_03215 5.34e-289 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
HGBEPDGP_03216 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
HGBEPDGP_03217 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
HGBEPDGP_03218 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
HGBEPDGP_03219 3.14e-254 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
HGBEPDGP_03220 6.74e-112 alaR - - K - - - Transcriptional regulator
HGBEPDGP_03221 9.89e-201 yugF - - I - - - Hydrolase
HGBEPDGP_03222 8.84e-52 yugE - - S - - - Domain of unknown function (DUF1871)
HGBEPDGP_03223 4.53e-284 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HGBEPDGP_03224 1.06e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HGBEPDGP_03225 1.44e-90 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
HGBEPDGP_03226 8.49e-150 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
HGBEPDGP_03228 8.9e-242 yuxJ - - EGP - - - Major facilitator superfamily
HGBEPDGP_03229 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
HGBEPDGP_03230 3.31e-98 yuxK - - S - - - protein conserved in bacteria
HGBEPDGP_03231 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
HGBEPDGP_03232 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HGBEPDGP_03233 3.26e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
HGBEPDGP_03234 1.84e-246 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
HGBEPDGP_03235 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HGBEPDGP_03236 1.29e-236 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HGBEPDGP_03237 6.97e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HGBEPDGP_03238 7.99e-309 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
HGBEPDGP_03239 1.73e-22 - - - - - - - -
HGBEPDGP_03240 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HGBEPDGP_03241 6.3e-90 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HGBEPDGP_03242 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HGBEPDGP_03243 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HGBEPDGP_03244 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HGBEPDGP_03245 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HGBEPDGP_03246 9.92e-78 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
HGBEPDGP_03247 2.24e-82 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
HGBEPDGP_03248 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGBEPDGP_03249 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HGBEPDGP_03251 8.19e-169 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
HGBEPDGP_03252 6.29e-10 - - - S - - - DegQ (SacQ) family
HGBEPDGP_03253 8.73e-09 yuzC - - - - - - -
HGBEPDGP_03254 2.92e-298 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
HGBEPDGP_03255 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HGBEPDGP_03256 7.71e-133 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
HGBEPDGP_03257 3.64e-86 - - - S - - - Protein of unknown function (DUF1694)
HGBEPDGP_03258 1.63e-52 yueH - - S - - - YueH-like protein
HGBEPDGP_03259 2.05e-42 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
HGBEPDGP_03260 5.5e-244 yueF - - S - - - transporter activity
HGBEPDGP_03261 7.71e-91 - - - S - - - Protein of unknown function (DUF2283)
HGBEPDGP_03262 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
HGBEPDGP_03263 1.91e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
HGBEPDGP_03264 2.04e-169 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGBEPDGP_03265 1.78e-96 yueC - - S - - - Family of unknown function (DUF5383)
HGBEPDGP_03266 0.0 yueB - - S - - - type VII secretion protein EsaA
HGBEPDGP_03267 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HGBEPDGP_03268 3.93e-270 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
HGBEPDGP_03269 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
HGBEPDGP_03270 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
HGBEPDGP_03271 8.49e-292 yukF - - QT - - - Transcriptional regulator
HGBEPDGP_03272 4.02e-262 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
HGBEPDGP_03273 1.2e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
HGBEPDGP_03274 4.08e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
HGBEPDGP_03275 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGBEPDGP_03276 4.47e-228 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
HGBEPDGP_03277 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
HGBEPDGP_03278 7.34e-291 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
HGBEPDGP_03279 5.83e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HGBEPDGP_03280 8.58e-211 eSD - - S ko:K07017 - ko00000 Putative esterase
HGBEPDGP_03281 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
HGBEPDGP_03282 4.81e-124 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
HGBEPDGP_03283 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
HGBEPDGP_03284 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HGBEPDGP_03285 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
HGBEPDGP_03286 3.14e-149 yuiC - - S - - - protein conserved in bacteria
HGBEPDGP_03287 1.14e-45 yuiB - - S - - - Putative membrane protein
HGBEPDGP_03288 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HGBEPDGP_03289 2.84e-218 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
HGBEPDGP_03291 4.51e-235 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HGBEPDGP_03292 8.15e-149 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
HGBEPDGP_03293 3.98e-115 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGBEPDGP_03294 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
HGBEPDGP_03295 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HGBEPDGP_03296 6.25e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HGBEPDGP_03297 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
HGBEPDGP_03298 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HGBEPDGP_03299 5.44e-74 yuzD - - S - - - protein conserved in bacteria
HGBEPDGP_03300 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
HGBEPDGP_03301 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
HGBEPDGP_03302 2.57e-221 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HGBEPDGP_03303 2.4e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HGBEPDGP_03304 1.67e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
HGBEPDGP_03305 1.55e-253 yutH - - S - - - Spore coat protein
HGBEPDGP_03306 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
HGBEPDGP_03307 3.69e-183 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HGBEPDGP_03308 2.38e-99 yutE - - S - - - Protein of unknown function DUF86
HGBEPDGP_03309 3.2e-63 yutD - - S - - - protein conserved in bacteria
HGBEPDGP_03310 2.71e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HGBEPDGP_03311 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HGBEPDGP_03312 2.66e-252 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
HGBEPDGP_03313 4.25e-172 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
HGBEPDGP_03314 3.28e-63 yunC - - S - - - Domain of unknown function (DUF1805)
HGBEPDGP_03315 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HGBEPDGP_03316 6.51e-181 yunE - - S ko:K07090 - ko00000 membrane transporter protein
HGBEPDGP_03317 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
HGBEPDGP_03318 1.07e-79 yunG - - - - - - -
HGBEPDGP_03319 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HGBEPDGP_03320 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
HGBEPDGP_03321 2.82e-298 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
HGBEPDGP_03322 1.84e-282 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
HGBEPDGP_03323 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HGBEPDGP_03324 2.01e-70 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HGBEPDGP_03325 5.71e-121 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HGBEPDGP_03326 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HGBEPDGP_03327 8.04e-193 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HGBEPDGP_03328 6.18e-143 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
HGBEPDGP_03329 2.73e-238 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HGBEPDGP_03330 5.74e-304 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HGBEPDGP_03331 1.64e-301 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HGBEPDGP_03332 1.8e-215 bsn - - L - - - Ribonuclease
HGBEPDGP_03333 2.42e-262 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HGBEPDGP_03334 5.04e-174 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
HGBEPDGP_03335 5.1e-204 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
HGBEPDGP_03336 4.58e-215 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
HGBEPDGP_03337 3.54e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGBEPDGP_03338 6.75e-306 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
HGBEPDGP_03339 5.27e-235 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HGBEPDGP_03340 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
HGBEPDGP_03341 3.8e-203 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
HGBEPDGP_03342 3.31e-36 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
HGBEPDGP_03344 3.35e-56 - - - - - - - -
HGBEPDGP_03345 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
HGBEPDGP_03346 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
HGBEPDGP_03347 1.14e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HGBEPDGP_03348 7.43e-313 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
HGBEPDGP_03349 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HGBEPDGP_03350 1.56e-80 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HGBEPDGP_03351 1.01e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
HGBEPDGP_03352 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
HGBEPDGP_03353 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HGBEPDGP_03354 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
HGBEPDGP_03355 2e-73 yusE - - CO - - - Thioredoxin
HGBEPDGP_03356 7.62e-97 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
HGBEPDGP_03357 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
HGBEPDGP_03358 3.42e-84 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HGBEPDGP_03359 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
HGBEPDGP_03360 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
HGBEPDGP_03361 1.34e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
HGBEPDGP_03362 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
HGBEPDGP_03363 1.11e-13 - - - S - - - YuzL-like protein
HGBEPDGP_03364 2.84e-210 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
HGBEPDGP_03365 2.23e-54 - - - - - - - -
HGBEPDGP_03366 8.66e-70 yusN - - M - - - Coat F domain
HGBEPDGP_03367 4.47e-98 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
HGBEPDGP_03368 0.0 yusP - - P - - - Major facilitator superfamily
HGBEPDGP_03369 2.93e-85 yusQ - - S - - - Tautomerase enzyme
HGBEPDGP_03370 8.6e-139 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HGBEPDGP_03371 8.42e-204 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
HGBEPDGP_03372 3.66e-64 yusU - - S - - - Protein of unknown function (DUF2573)
HGBEPDGP_03373 1.06e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HGBEPDGP_03374 2.86e-87 - - - S - - - YusW-like protein
HGBEPDGP_03375 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
HGBEPDGP_03376 1.1e-196 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HGBEPDGP_03377 8.76e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
HGBEPDGP_03378 5.56e-305 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HGBEPDGP_03379 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGBEPDGP_03380 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HGBEPDGP_03381 3.06e-204 yuxN - - K - - - Transcriptional regulator
HGBEPDGP_03382 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HGBEPDGP_03383 4.48e-34 - - - S - - - Protein of unknown function (DUF3970)
HGBEPDGP_03384 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
HGBEPDGP_03385 2.9e-253 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
HGBEPDGP_03386 3.48e-249 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
HGBEPDGP_03387 9.39e-141 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGBEPDGP_03388 2.74e-244 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HGBEPDGP_03389 7.65e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
HGBEPDGP_03390 2.48e-166 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
HGBEPDGP_03391 2.44e-143 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HGBEPDGP_03392 6.17e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
HGBEPDGP_03393 6.23e-286 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HGBEPDGP_03394 2.96e-130 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
HGBEPDGP_03395 3.76e-316 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HGBEPDGP_03396 6.35e-235 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGBEPDGP_03397 3.48e-217 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HGBEPDGP_03398 2.12e-181 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HGBEPDGP_03399 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
HGBEPDGP_03400 0.0 yvrG - - T - - - Histidine kinase
HGBEPDGP_03401 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGBEPDGP_03402 5.07e-32 - - - - - - - -
HGBEPDGP_03403 6.74e-126 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
HGBEPDGP_03404 3.46e-26 - - - S - - - YvrJ protein family
HGBEPDGP_03405 4.39e-290 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
HGBEPDGP_03406 8.13e-85 yvrL - - S - - - Regulatory protein YrvL
HGBEPDGP_03407 3.36e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
HGBEPDGP_03408 3.82e-158 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HGBEPDGP_03409 3.61e-231 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
HGBEPDGP_03410 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HGBEPDGP_03411 3.76e-223 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGBEPDGP_03412 2e-235 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGBEPDGP_03413 4.45e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HGBEPDGP_03415 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
HGBEPDGP_03416 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
HGBEPDGP_03417 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
HGBEPDGP_03418 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
HGBEPDGP_03419 4.91e-212 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
HGBEPDGP_03420 2.11e-175 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
HGBEPDGP_03421 1.95e-150 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
HGBEPDGP_03422 6.19e-201 yvgN - - S - - - reductase
HGBEPDGP_03423 7.97e-113 yvgO - - - - - - -
HGBEPDGP_03424 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
HGBEPDGP_03425 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HGBEPDGP_03426 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HGBEPDGP_03427 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HGBEPDGP_03429 2.34e-139 yvgT - - S - - - membrane
HGBEPDGP_03430 1.99e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
HGBEPDGP_03431 3.45e-137 bdbD - - O - - - Thioredoxin
HGBEPDGP_03432 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
HGBEPDGP_03433 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HGBEPDGP_03434 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
HGBEPDGP_03435 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
HGBEPDGP_03436 1.71e-248 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
HGBEPDGP_03437 2.08e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HGBEPDGP_03438 0.0 - - - S - - - Fusaric acid resistance protein-like
HGBEPDGP_03439 2.02e-97 yvaD - - S - - - Family of unknown function (DUF5360)
HGBEPDGP_03440 3.52e-71 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
HGBEPDGP_03441 1.51e-123 - - - K - - - Bacterial regulatory proteins, tetR family
HGBEPDGP_03442 9.32e-181 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HGBEPDGP_03444 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HGBEPDGP_03445 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HGBEPDGP_03446 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
HGBEPDGP_03447 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
HGBEPDGP_03448 5.5e-194 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
HGBEPDGP_03449 3.44e-48 yvzC - - K - - - transcriptional
HGBEPDGP_03450 4.08e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
HGBEPDGP_03451 9.82e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
HGBEPDGP_03452 3.85e-72 yvaP - - K - - - transcriptional
HGBEPDGP_03453 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HGBEPDGP_03454 1.31e-143 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HGBEPDGP_03455 3.37e-220 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HGBEPDGP_03456 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HGBEPDGP_03457 8.57e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HGBEPDGP_03458 6.63e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
HGBEPDGP_03459 1.37e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HGBEPDGP_03460 4.11e-220 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HGBEPDGP_03461 4.63e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HGBEPDGP_03462 5.58e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HGBEPDGP_03463 8.29e-129 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
HGBEPDGP_03464 7.95e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
HGBEPDGP_03465 9.9e-144 yvbH - - S - - - YvbH-like oligomerisation region
HGBEPDGP_03466 1.61e-156 yvbI - - M - - - Membrane
HGBEPDGP_03467 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
HGBEPDGP_03468 6.87e-106 yvbK - - K - - - acetyltransferase
HGBEPDGP_03469 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HGBEPDGP_03470 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
HGBEPDGP_03471 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HGBEPDGP_03472 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
HGBEPDGP_03473 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HGBEPDGP_03474 2.42e-237 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HGBEPDGP_03475 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HGBEPDGP_03476 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
HGBEPDGP_03477 1.04e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGBEPDGP_03479 5.49e-205 yvbU - - K - - - Transcriptional regulator
HGBEPDGP_03480 3.93e-198 yvbV - - EG - - - EamA-like transporter family
HGBEPDGP_03481 1.43e-306 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HGBEPDGP_03482 1.22e-248 - - - S - - - Glycosyl hydrolase
HGBEPDGP_03483 2.92e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HGBEPDGP_03484 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HGBEPDGP_03485 2.6e-174 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HGBEPDGP_03486 2.07e-134 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGBEPDGP_03487 7.33e-250 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HGBEPDGP_03488 5.01e-171 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
HGBEPDGP_03489 1.7e-208 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
HGBEPDGP_03490 4.2e-200 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
HGBEPDGP_03491 2.93e-263 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
HGBEPDGP_03492 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
HGBEPDGP_03493 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
HGBEPDGP_03494 1.1e-193 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
HGBEPDGP_03495 2.15e-300 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
HGBEPDGP_03496 1.68e-294 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
HGBEPDGP_03497 6.42e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HGBEPDGP_03498 6.85e-146 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
HGBEPDGP_03499 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HGBEPDGP_03500 3.35e-304 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HGBEPDGP_03501 5.69e-44 yvfG - - S - - - YvfG protein
HGBEPDGP_03502 7.54e-241 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
HGBEPDGP_03503 1.91e-281 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
HGBEPDGP_03504 8.22e-77 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
HGBEPDGP_03505 7.83e-140 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HGBEPDGP_03506 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HGBEPDGP_03507 2.36e-246 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
HGBEPDGP_03508 4.13e-254 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
HGBEPDGP_03509 3.5e-248 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
HGBEPDGP_03510 3.59e-264 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
HGBEPDGP_03511 5.9e-277 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HGBEPDGP_03512 2.16e-202 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
HGBEPDGP_03513 4.5e-281 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
HGBEPDGP_03514 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
HGBEPDGP_03515 7.94e-150 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
HGBEPDGP_03516 2.78e-158 epsA - - M ko:K19420 - ko00000 biosynthesis protein
HGBEPDGP_03517 3.57e-98 - - - K ko:K19417 - ko00000,ko03000 transcriptional
HGBEPDGP_03518 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
HGBEPDGP_03520 3.13e-119 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
HGBEPDGP_03521 7.42e-95 - - - S - - - Protein of unknown function (DUF3237)
HGBEPDGP_03522 1.76e-162 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HGBEPDGP_03523 0.0 pbpE - - V - - - Beta-lactamase
HGBEPDGP_03524 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
HGBEPDGP_03525 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
HGBEPDGP_03526 0.0 ybeC - - E - - - amino acid
HGBEPDGP_03527 4.76e-137 yvdT_1 - - K - - - Transcriptional regulator
HGBEPDGP_03528 2.57e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
HGBEPDGP_03529 1.03e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
HGBEPDGP_03530 5.53e-122 yvdQ - - S - - - Protein of unknown function (DUF3231)
HGBEPDGP_03531 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
HGBEPDGP_03532 9.45e-234 - - - S - - - Patatin-like phospholipase
HGBEPDGP_03534 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HGBEPDGP_03535 2.91e-156 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HGBEPDGP_03536 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
HGBEPDGP_03537 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
HGBEPDGP_03538 3.96e-197 malA - - S - - - Protein of unknown function (DUF1189)
HGBEPDGP_03539 6.84e-190 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
HGBEPDGP_03540 8.65e-311 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
HGBEPDGP_03541 1.63e-299 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
HGBEPDGP_03542 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
HGBEPDGP_03543 1.54e-221 yvdE - - K - - - Transcriptional regulator
HGBEPDGP_03544 2.66e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HGBEPDGP_03545 7.84e-71 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
HGBEPDGP_03546 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
HGBEPDGP_03547 3.73e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
HGBEPDGP_03548 1.15e-234 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGBEPDGP_03549 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
HGBEPDGP_03550 4.46e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HGBEPDGP_03551 1.32e-249 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
HGBEPDGP_03552 4.67e-172 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGBEPDGP_03553 1.37e-45 - - - - - - - -
HGBEPDGP_03554 8.35e-185 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
HGBEPDGP_03555 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
HGBEPDGP_03556 3.63e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HGBEPDGP_03557 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
HGBEPDGP_03558 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HGBEPDGP_03559 2.39e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HGBEPDGP_03560 8.31e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HGBEPDGP_03561 2.18e-184 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
HGBEPDGP_03562 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
HGBEPDGP_03563 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
HGBEPDGP_03565 0.0 - - - - - - - -
HGBEPDGP_03566 6.36e-172 - - - - - - - -
HGBEPDGP_03567 2.61e-146 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
HGBEPDGP_03568 5.63e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HGBEPDGP_03569 1.32e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HGBEPDGP_03570 1.15e-146 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HGBEPDGP_03571 2.87e-138 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
HGBEPDGP_03572 3e-291 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HGBEPDGP_03573 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HGBEPDGP_03574 2.42e-281 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HGBEPDGP_03575 5.03e-178 yvpB - - NU - - - protein conserved in bacteria
HGBEPDGP_03576 1.1e-153 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
HGBEPDGP_03577 5.94e-118 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
HGBEPDGP_03578 3.05e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HGBEPDGP_03579 3.72e-211 yvoD - - P - - - COG0370 Fe2 transport system protein B
HGBEPDGP_03580 2.61e-194 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HGBEPDGP_03581 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HGBEPDGP_03582 9.39e-277 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
HGBEPDGP_03583 2.12e-166 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HGBEPDGP_03584 5.23e-172 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
HGBEPDGP_03585 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
HGBEPDGP_03586 9.4e-110 yvnA - - K - - - helix_turn_helix multiple antibiotic resistance protein
HGBEPDGP_03587 9.32e-293 cypX 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HGBEPDGP_03588 2.49e-177 yvmC 2.3.2.22 - S ko:K17485 - ko00000,ko01000 Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
HGBEPDGP_03589 1.03e-112 yvmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
HGBEPDGP_03590 4.26e-272 yvmA - - EGP - - - Major Facilitator Superfamily
HGBEPDGP_03591 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
HGBEPDGP_03592 2.49e-35 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
HGBEPDGP_03593 1.12e-218 yvlB - - S - - - Putative adhesin
HGBEPDGP_03594 3.3e-64 yvlA - - - - - - -
HGBEPDGP_03595 2.25e-45 yvkN - - - - - - -
HGBEPDGP_03596 3.03e-147 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HGBEPDGP_03597 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HGBEPDGP_03598 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HGBEPDGP_03599 2.54e-42 csbA - - S - - - protein conserved in bacteria
HGBEPDGP_03600 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
HGBEPDGP_03601 2.36e-130 yvkB - - K - - - Transcriptional regulator
HGBEPDGP_03602 5.24e-296 yvkA - - P - - - -transporter
HGBEPDGP_03603 3.17e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HGBEPDGP_03604 1.38e-73 swrA - - S - - - Swarming motility protein
HGBEPDGP_03605 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HGBEPDGP_03606 3.02e-196 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HGBEPDGP_03607 3.03e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
HGBEPDGP_03608 3.23e-75 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
HGBEPDGP_03609 6.5e-185 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HGBEPDGP_03610 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HGBEPDGP_03611 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HGBEPDGP_03612 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HGBEPDGP_03613 9.14e-88 - - - - - - - -
HGBEPDGP_03614 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
HGBEPDGP_03615 8.56e-90 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
HGBEPDGP_03616 8.97e-313 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HGBEPDGP_03617 1.62e-69 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
HGBEPDGP_03618 1.43e-124 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HGBEPDGP_03619 5.02e-39 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HGBEPDGP_03620 5e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HGBEPDGP_03621 6.92e-92 yviE - - - - - - -
HGBEPDGP_03622 3.8e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
HGBEPDGP_03623 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
HGBEPDGP_03624 7.06e-102 yvyG - - NOU - - - FlgN protein
HGBEPDGP_03625 4.32e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
HGBEPDGP_03626 1.83e-96 yvyF - - S - - - flagellar protein
HGBEPDGP_03627 7.56e-161 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
HGBEPDGP_03628 1.04e-60 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
HGBEPDGP_03629 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HGBEPDGP_03630 1.77e-198 degV - - S - - - protein conserved in bacteria
HGBEPDGP_03631 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGBEPDGP_03632 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HGBEPDGP_03633 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
HGBEPDGP_03634 3.81e-223 yvhJ - - K - - - Transcriptional regulator
HGBEPDGP_03635 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HGBEPDGP_03636 3.69e-300 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
HGBEPDGP_03637 8.42e-187 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
HGBEPDGP_03638 5.79e-147 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
HGBEPDGP_03639 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
HGBEPDGP_03640 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HGBEPDGP_03641 5.68e-279 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
HGBEPDGP_03642 2.58e-316 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HGBEPDGP_03643 1.49e-143 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HGBEPDGP_03644 7e-108 - - - M - - - Glycosyltransferase like family 2
HGBEPDGP_03645 2.25e-265 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
HGBEPDGP_03646 0.0 lytB - - D - - - Stage II sporulation protein
HGBEPDGP_03647 9.07e-16 - - - - - - - -
HGBEPDGP_03648 1.16e-211 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HGBEPDGP_03649 7.71e-277 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HGBEPDGP_03650 2.94e-103 - - - M - - - Glycosyltransferase like family 2
HGBEPDGP_03651 3.05e-119 - - - M - - - Glycosyl transferases group 1
HGBEPDGP_03653 2.74e-208 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HGBEPDGP_03654 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HGBEPDGP_03655 1.95e-167 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
HGBEPDGP_03656 7.8e-102 - - - - - - - -
HGBEPDGP_03657 5.37e-68 - - - - - - - -
HGBEPDGP_03658 7.58e-249 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HGBEPDGP_03659 4.14e-106 - - - M - - - Glycosyltransferase like family 2
HGBEPDGP_03660 6.53e-180 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HGBEPDGP_03661 1.32e-73 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
HGBEPDGP_03662 6.82e-111 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HGBEPDGP_03663 1.01e-129 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HGBEPDGP_03664 1.46e-134 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HGBEPDGP_03665 5.68e-186 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HGBEPDGP_03666 6.69e-110 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - M ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HGBEPDGP_03667 1.42e-235 tarL 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HGBEPDGP_03668 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HGBEPDGP_03669 9.14e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HGBEPDGP_03670 3.12e-310 gerBA - - EG ko:K06291,ko:K06310 - ko00000 Spore germination protein
HGBEPDGP_03671 3.4e-238 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
HGBEPDGP_03672 1.95e-251 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
HGBEPDGP_03673 2.27e-315 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HGBEPDGP_03674 1.42e-220 ywtF_2 - - K - - - Transcriptional regulator
HGBEPDGP_03675 4.69e-201 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
HGBEPDGP_03676 1.37e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HGBEPDGP_03677 2.29e-29 ywtC - - - - - - -
HGBEPDGP_03678 1.1e-276 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HGBEPDGP_03679 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
HGBEPDGP_03680 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
HGBEPDGP_03681 2.68e-227 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
HGBEPDGP_03682 1.85e-206 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HGBEPDGP_03683 4.61e-84 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HGBEPDGP_03684 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HGBEPDGP_03685 3.35e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HGBEPDGP_03686 9.04e-204 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
HGBEPDGP_03687 1.62e-118 batE - - T - - - Sh3 type 3 domain protein
HGBEPDGP_03688 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
HGBEPDGP_03689 8.76e-126 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
HGBEPDGP_03690 1.84e-187 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
HGBEPDGP_03691 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HGBEPDGP_03692 3.36e-218 alsR - - K - - - LysR substrate binding domain
HGBEPDGP_03693 1.68e-281 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HGBEPDGP_03694 2.5e-161 ywrJ - - - - - - -
HGBEPDGP_03695 1.37e-194 cotB - - - ko:K06325 - ko00000 -
HGBEPDGP_03696 2.64e-268 cotH - - M ko:K06330 - ko00000 Spore Coat
HGBEPDGP_03697 2.17e-16 - - - - - - - -
HGBEPDGP_03698 1.77e-142 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HGBEPDGP_03699 2.78e-71 - - - S - - - Domain of unknown function (DUF4181)
HGBEPDGP_03700 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
HGBEPDGP_03701 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
HGBEPDGP_03702 6.44e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
HGBEPDGP_03703 3.51e-113 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
HGBEPDGP_03705 6.11e-129 ywqN - - S - - - NAD(P)H-dependent
HGBEPDGP_03706 3.33e-209 - - - K - - - Transcriptional regulator
HGBEPDGP_03707 8.51e-155 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HGBEPDGP_03708 1.13e-126 - - - - - - - -
HGBEPDGP_03710 2.2e-66 - - - - - - - -
HGBEPDGP_03711 1.29e-97 - - - - - - - -
HGBEPDGP_03712 1.95e-297 ywqJ - - S - - - Pre-toxin TG
HGBEPDGP_03713 4.98e-50 ywqI - - S - - - Family of unknown function (DUF5344)
HGBEPDGP_03715 1.71e-195 ywqG - - S - - - Domain of unknown function (DUF1963)
HGBEPDGP_03716 1.34e-312 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HGBEPDGP_03717 6.38e-183 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
HGBEPDGP_03718 1.06e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
HGBEPDGP_03719 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
HGBEPDGP_03720 3.6e-25 - - - - - - - -
HGBEPDGP_03721 0.0 ywqB - - S - - - SWIM zinc finger
HGBEPDGP_03722 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
HGBEPDGP_03723 5.91e-199 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
HGBEPDGP_03724 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HGBEPDGP_03725 1.04e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
HGBEPDGP_03726 3.56e-86 ywpG - - - - - - -
HGBEPDGP_03727 3.59e-88 ywpF - - S - - - YwpF-like protein
HGBEPDGP_03728 6.34e-66 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
HGBEPDGP_03729 2.51e-18 - - - M - - - cell wall anchor domain
HGBEPDGP_03730 1.28e-66 ywpD - - T - - - Histidine kinase
HGBEPDGP_03731 1.61e-77 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HGBEPDGP_03732 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HGBEPDGP_03733 1.5e-254 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
HGBEPDGP_03734 1.17e-181 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
HGBEPDGP_03735 9.79e-170 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
HGBEPDGP_03736 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
HGBEPDGP_03737 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
HGBEPDGP_03738 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
HGBEPDGP_03739 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HGBEPDGP_03740 2.4e-311 ywoF - - P - - - Right handed beta helix region
HGBEPDGP_03741 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
HGBEPDGP_03742 5.39e-307 ywoD - - EGP - - - Major facilitator superfamily
HGBEPDGP_03743 1.04e-133 yjgF - - Q - - - Isochorismatase family
HGBEPDGP_03744 5.04e-101 - - - - - - - -
HGBEPDGP_03745 6.5e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
HGBEPDGP_03746 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
HGBEPDGP_03747 1.21e-134 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
HGBEPDGP_03748 7.75e-94 ywnJ - - S - - - VanZ like family
HGBEPDGP_03749 1.85e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
HGBEPDGP_03750 7.38e-115 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
HGBEPDGP_03751 1.29e-16 ywnC - - S - - - Family of unknown function (DUF5362)
HGBEPDGP_03752 1.43e-91 ywnF - - S - - - Family of unknown function (DUF5392)
HGBEPDGP_03753 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HGBEPDGP_03754 2.31e-182 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
HGBEPDGP_03755 1.24e-77 ywnC - - S - - - Family of unknown function (DUF5362)
HGBEPDGP_03756 1.69e-144 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
HGBEPDGP_03757 2.65e-84 ywnA - - K - - - Transcriptional regulator
HGBEPDGP_03758 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HGBEPDGP_03759 1.12e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
HGBEPDGP_03760 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
HGBEPDGP_03762 1.84e-20 csbD - - K - - - CsbD-like
HGBEPDGP_03763 1.12e-109 ywmF - - S - - - Peptidase M50
HGBEPDGP_03764 1.25e-128 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HGBEPDGP_03765 2.65e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HGBEPDGP_03766 3.69e-186 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HGBEPDGP_03768 1.44e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
HGBEPDGP_03769 1.56e-156 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
HGBEPDGP_03770 3.41e-234 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
HGBEPDGP_03771 1e-305 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HGBEPDGP_03772 2.68e-171 ywmB - - S - - - TATA-box binding
HGBEPDGP_03773 4.54e-45 ywzB - - S - - - membrane
HGBEPDGP_03774 2.8e-111 ywmA - - - - - - -
HGBEPDGP_03775 2.44e-75 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HGBEPDGP_03776 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HGBEPDGP_03777 4.46e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HGBEPDGP_03778 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HGBEPDGP_03779 9.66e-117 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HGBEPDGP_03780 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HGBEPDGP_03781 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HGBEPDGP_03782 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HGBEPDGP_03783 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
HGBEPDGP_03784 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HGBEPDGP_03785 4.36e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HGBEPDGP_03786 2.9e-122 ywlG - - S - - - Belongs to the UPF0340 family
HGBEPDGP_03787 1.36e-105 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
HGBEPDGP_03788 1.58e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HGBEPDGP_03789 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
HGBEPDGP_03790 1.22e-249 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HGBEPDGP_03791 1.04e-99 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
HGBEPDGP_03792 1.55e-150 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
HGBEPDGP_03793 5.61e-73 ywlA - - S - - - Uncharacterised protein family (UPF0715)
HGBEPDGP_03795 2.23e-200 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HGBEPDGP_03796 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HGBEPDGP_03797 1.19e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGBEPDGP_03798 6.01e-117 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HGBEPDGP_03799 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
HGBEPDGP_03800 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
HGBEPDGP_03801 9.96e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HGBEPDGP_03802 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
HGBEPDGP_03803 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HGBEPDGP_03804 2.03e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
HGBEPDGP_03805 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HGBEPDGP_03806 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HGBEPDGP_03807 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
HGBEPDGP_03808 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
HGBEPDGP_03809 3.86e-119 ywjG - - S - - - Domain of unknown function (DUF2529)
HGBEPDGP_03810 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HGBEPDGP_03811 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HGBEPDGP_03812 4.95e-268 acdA - - I - - - acyl-CoA dehydrogenase
HGBEPDGP_03813 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
HGBEPDGP_03814 2.86e-288 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HGBEPDGP_03815 1.4e-235 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HGBEPDGP_03816 1.32e-57 ywjC - - - - - - -
HGBEPDGP_03817 2.61e-122 ywjB - - H - - - RibD C-terminal domain
HGBEPDGP_03818 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
HGBEPDGP_03819 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HGBEPDGP_03820 4.85e-158 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
HGBEPDGP_03821 2.28e-121 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
HGBEPDGP_03822 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
HGBEPDGP_03823 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HGBEPDGP_03824 3.53e-110 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
HGBEPDGP_03825 1.51e-178 ywiC - - S - - - YwiC-like protein
HGBEPDGP_03826 2.3e-168 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
HGBEPDGP_03827 1.2e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
HGBEPDGP_03828 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HGBEPDGP_03829 4.64e-96 ywiB - - S - - - protein conserved in bacteria
HGBEPDGP_03830 3.71e-12 - - - S - - - Bacteriocin subtilosin A
HGBEPDGP_03831 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
HGBEPDGP_03833 1.5e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HGBEPDGP_03834 2.21e-293 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
HGBEPDGP_03835 1.56e-272 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
HGBEPDGP_03836 7.81e-316 - - - L - - - Peptidase, M16
HGBEPDGP_03838 9.08e-317 ywhL - - CO - - - amine dehydrogenase activity
HGBEPDGP_03839 9.47e-275 ywhK - - CO - - - amine dehydrogenase activity
HGBEPDGP_03840 2.32e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HGBEPDGP_03842 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
HGBEPDGP_03843 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HGBEPDGP_03844 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HGBEPDGP_03845 7.83e-123 ywhD - - S - - - YwhD family
HGBEPDGP_03846 3.29e-154 ywhC - - S - - - Peptidase family M50
HGBEPDGP_03847 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
HGBEPDGP_03848 1.76e-94 ywhA - - K - - - Transcriptional regulator
HGBEPDGP_03849 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HGBEPDGP_03851 1.07e-300 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
HGBEPDGP_03852 1.28e-102 yffB - - K - - - Transcriptional regulator
HGBEPDGP_03853 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
HGBEPDGP_03854 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
HGBEPDGP_03855 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
HGBEPDGP_03856 5.65e-147 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
HGBEPDGP_03857 5.26e-203 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
HGBEPDGP_03858 2.15e-199 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HGBEPDGP_03859 7.53e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
HGBEPDGP_03860 1.67e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
HGBEPDGP_03861 1.4e-186 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
HGBEPDGP_03862 3.52e-178 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
HGBEPDGP_03863 4.46e-297 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
HGBEPDGP_03864 6.47e-267 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
HGBEPDGP_03865 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HGBEPDGP_03866 1.33e-179 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGBEPDGP_03867 7.2e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HGBEPDGP_03868 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HGBEPDGP_03869 1.09e-274 ywfA - - EGP - - - -transporter
HGBEPDGP_03870 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HGBEPDGP_03871 0.0 rocB - - E - - - arginine degradation protein
HGBEPDGP_03872 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
HGBEPDGP_03873 5.19e-311 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HGBEPDGP_03874 1.1e-102 - - - - - - - -
HGBEPDGP_03875 9.16e-114 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
HGBEPDGP_03876 2.44e-206 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HGBEPDGP_03877 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HGBEPDGP_03878 2.6e-178 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HGBEPDGP_03879 2.54e-243 spsG - - M - - - Spore Coat
HGBEPDGP_03880 4.64e-169 spsF - - M ko:K07257 - ko00000 Spore Coat
HGBEPDGP_03881 1.13e-270 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
HGBEPDGP_03882 8.51e-210 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
HGBEPDGP_03883 1.85e-284 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
HGBEPDGP_03884 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
HGBEPDGP_03885 2.32e-186 spsA - - M - - - Spore Coat
HGBEPDGP_03886 3.62e-112 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HGBEPDGP_03887 1.59e-78 ywdK - - S - - - small membrane protein
HGBEPDGP_03888 1.86e-303 ywdJ - - F - - - Xanthine uracil
HGBEPDGP_03889 2.18e-63 ywdI - - S - - - Family of unknown function (DUF5327)
HGBEPDGP_03890 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HGBEPDGP_03891 9.47e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HGBEPDGP_03892 1.9e-191 ywdF - - S - - - Glycosyltransferase like family 2
HGBEPDGP_03894 8.74e-146 ywdD - - - - - - -
HGBEPDGP_03895 7.92e-76 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
HGBEPDGP_03896 7.39e-186 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HGBEPDGP_03897 6.19e-39 ywdA - - - - - - -
HGBEPDGP_03898 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
HGBEPDGP_03899 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HGBEPDGP_03900 8e-178 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
HGBEPDGP_03901 1.29e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HGBEPDGP_03903 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HGBEPDGP_03904 3.44e-238 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGBEPDGP_03905 5.44e-177 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
HGBEPDGP_03906 1.26e-268 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HGBEPDGP_03907 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
HGBEPDGP_03908 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
HGBEPDGP_03909 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
HGBEPDGP_03910 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HGBEPDGP_03911 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HGBEPDGP_03912 5.11e-49 ydaS - - S - - - membrane
HGBEPDGP_03913 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HGBEPDGP_03914 2.27e-290 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HGBEPDGP_03915 3.33e-77 gtcA - - S - - - GtrA-like protein
HGBEPDGP_03916 4.16e-159 ywcC - - K - - - transcriptional regulator
HGBEPDGP_03918 7.41e-65 ywcB - - S - - - Protein of unknown function, DUF485
HGBEPDGP_03919 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HGBEPDGP_03920 2.17e-145 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
HGBEPDGP_03921 2.54e-307 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
HGBEPDGP_03922 1.4e-245 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
HGBEPDGP_03923 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
HGBEPDGP_03924 1.74e-146 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HGBEPDGP_03925 3.79e-184 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HGBEPDGP_03926 2.7e-203 ywbI - - K - - - Transcriptional regulator
HGBEPDGP_03927 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HGBEPDGP_03928 1.21e-143 ywbG - - M - - - effector of murein hydrolase
HGBEPDGP_03929 1.76e-276 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
HGBEPDGP_03930 6.33e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
HGBEPDGP_03931 4e-280 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
HGBEPDGP_03932 1.99e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
HGBEPDGP_03933 1.59e-315 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HGBEPDGP_03934 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HGBEPDGP_03935 1.45e-312 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HGBEPDGP_03936 2.6e-195 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HGBEPDGP_03937 4.41e-215 gspA - - M - - - General stress
HGBEPDGP_03938 1.66e-156 ywaF - - S - - - Integral membrane protein
HGBEPDGP_03939 4.18e-113 ywaE - - K - - - Transcriptional regulator
HGBEPDGP_03940 1.56e-297 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HGBEPDGP_03941 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
HGBEPDGP_03942 4.38e-115 - - - K - - - Helix-turn-helix XRE-family like proteins
HGBEPDGP_03943 7.93e-64 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
HGBEPDGP_03944 2.79e-165 - - - EGP - - - Permeases of the major facilitator superfamily
HGBEPDGP_03945 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
HGBEPDGP_03946 5.7e-210 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
HGBEPDGP_03947 1.27e-20 - - - S - - - D-Ala-teichoic acid biosynthesis protein
HGBEPDGP_03948 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGBEPDGP_03949 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
HGBEPDGP_03950 1.61e-48 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGBEPDGP_03951 8.26e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HGBEPDGP_03952 8e-176 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HGBEPDGP_03953 3.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HGBEPDGP_03954 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HGBEPDGP_03955 1.18e-67 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HGBEPDGP_03956 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HGBEPDGP_03957 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
HGBEPDGP_03958 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
HGBEPDGP_03959 8.94e-28 yxzF - - - - - - -
HGBEPDGP_03960 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
HGBEPDGP_03961 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
HGBEPDGP_03962 3.23e-270 yxlH - - EGP - - - Major Facilitator Superfamily
HGBEPDGP_03963 8.58e-174 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HGBEPDGP_03964 1.65e-210 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HGBEPDGP_03965 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
HGBEPDGP_03966 1.75e-43 - - - - - - - -
HGBEPDGP_03967 4.05e-64 yxlC - - S - - - Family of unknown function (DUF5345)
HGBEPDGP_03968 1.06e-123 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HGBEPDGP_03969 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
HGBEPDGP_03970 1.52e-201 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HGBEPDGP_03971 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
HGBEPDGP_03972 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
HGBEPDGP_03973 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
HGBEPDGP_03974 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
HGBEPDGP_03975 3.97e-310 cimH - - C - - - COG3493 Na citrate symporter
HGBEPDGP_03976 0.0 - - - O - - - Peptidase family M48
HGBEPDGP_03978 6.16e-198 yxkH - - G - - - Polysaccharide deacetylase
HGBEPDGP_03979 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HGBEPDGP_03980 3.89e-210 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
HGBEPDGP_03981 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HGBEPDGP_03982 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HGBEPDGP_03983 1.66e-98 yxkC - - S - - - Domain of unknown function (DUF4352)
HGBEPDGP_03984 2.11e-251 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HGBEPDGP_03985 7.69e-100 - - - S - - - Protein of unknown function (DUF1453)
HGBEPDGP_03986 4.59e-257 - - - T - - - Signal transduction histidine kinase
HGBEPDGP_03987 4.65e-149 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
HGBEPDGP_03988 2.6e-297 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HGBEPDGP_03991 1.43e-111 yxjI - - S - - - LURP-one-related
HGBEPDGP_03992 7.42e-278 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
HGBEPDGP_03993 9.77e-279 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
HGBEPDGP_03994 6.8e-175 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HGBEPDGP_03995 5.91e-151 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HGBEPDGP_03996 3.82e-167 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HGBEPDGP_03997 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
HGBEPDGP_03998 8.81e-204 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
HGBEPDGP_03999 2.1e-269 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HGBEPDGP_04000 2.83e-131 - - - T - - - Domain of unknown function (DUF4163)
HGBEPDGP_04001 5.39e-62 yxiS - - - - - - -
HGBEPDGP_04002 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
HGBEPDGP_04003 3.31e-283 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
HGBEPDGP_04004 1.46e-182 bglS - - M - - - licheninase activity
HGBEPDGP_04005 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HGBEPDGP_04006 4.37e-142 - - - - - - - -
HGBEPDGP_04007 4.43e-291 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
HGBEPDGP_04008 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HGBEPDGP_04009 2.37e-272 - - - E - - - GDSL-like Lipase/Acylhydrolase
HGBEPDGP_04010 1.86e-70 - - - K - - - Transcriptional regulator PadR-like family
HGBEPDGP_04011 2.16e-53 - - - S - - - Protein of unknown function (DUF2812)
HGBEPDGP_04012 2.34e-21 - - - S - - - YxiJ-like protein
HGBEPDGP_04013 0.0 wapA - - M - - - COG3209 Rhs family protein
HGBEPDGP_04014 8.44e-210 yxxF - - EG - - - EamA-like transporter family
HGBEPDGP_04015 2.2e-28 - - - - - - - -
HGBEPDGP_04016 2.01e-75 - - - K - - - helix_turn_helix, mercury resistance
HGBEPDGP_04018 1.24e-113 - - - - - - - -
HGBEPDGP_04019 2.77e-35 - - - S - - - Sporulation delaying protein SdpA
HGBEPDGP_04020 6.99e-94 yxiE - - T - - - Belongs to the universal stress protein A family
HGBEPDGP_04021 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HGBEPDGP_04022 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HGBEPDGP_04023 1.33e-62 - - - - - - - -
HGBEPDGP_04024 9.25e-103 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
HGBEPDGP_04025 6.09e-292 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
HGBEPDGP_04027 2.81e-26 - - - S - - - protein conserved in bacteria
HGBEPDGP_04029 2.14e-156 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
HGBEPDGP_04030 4.47e-51 yxiC - - S - - - Family of unknown function (DUF5344)
HGBEPDGP_04031 2.18e-36 - - - S - - - Domain of unknown function (DUF5082)
HGBEPDGP_04032 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
HGBEPDGP_04033 7.02e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HGBEPDGP_04034 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
HGBEPDGP_04035 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HGBEPDGP_04036 9.1e-299 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
HGBEPDGP_04037 2.8e-230 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HGBEPDGP_04038 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HGBEPDGP_04039 6.66e-298 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
HGBEPDGP_04040 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HGBEPDGP_04041 8.3e-150 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HGBEPDGP_04042 1.22e-221 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HGBEPDGP_04043 3.05e-196 - - - S - - - Domain of Unknown Function (DUF1206)
HGBEPDGP_04044 5.43e-256 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
HGBEPDGP_04045 0.0 yxeQ - - S - - - MmgE/PrpD family
HGBEPDGP_04046 1.17e-271 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
HGBEPDGP_04047 6.82e-171 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HGBEPDGP_04048 3e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HGBEPDGP_04049 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HGBEPDGP_04050 2.19e-121 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGBEPDGP_04051 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGBEPDGP_04052 9.11e-236 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
HGBEPDGP_04053 3.29e-193 yxeH - - S - - - hydrolases of the HAD superfamily
HGBEPDGP_04056 7.32e-42 yxeE - - - - - - -
HGBEPDGP_04057 7.57e-28 yxeD - - - - - - -
HGBEPDGP_04058 9.65e-91 - - - - - - - -
HGBEPDGP_04059 9.65e-223 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HGBEPDGP_04060 2e-75 yxeA - - S - - - Protein of unknown function (DUF1093)
HGBEPDGP_04061 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
HGBEPDGP_04062 9.39e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HGBEPDGP_04063 2.7e-231 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HGBEPDGP_04064 2.8e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGBEPDGP_04065 2.83e-204 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HGBEPDGP_04066 1.09e-186 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HGBEPDGP_04067 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
HGBEPDGP_04068 4.44e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HGBEPDGP_04069 4.68e-295 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
HGBEPDGP_04070 1.23e-222 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HGBEPDGP_04071 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HGBEPDGP_04072 2.48e-227 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HGBEPDGP_04073 9.89e-200 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HGBEPDGP_04074 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HGBEPDGP_04075 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HGBEPDGP_04076 3.52e-224 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
HGBEPDGP_04078 2.13e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
HGBEPDGP_04079 6.88e-312 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HGBEPDGP_04080 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
HGBEPDGP_04082 8.38e-193 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HGBEPDGP_04083 1.03e-265 yxbF - - K - - - Bacterial regulatory proteins, tetR family
HGBEPDGP_04084 9.79e-313 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HGBEPDGP_04085 2.09e-16 yxaI - - S - - - membrane protein domain
HGBEPDGP_04086 1.73e-135 yxaL - - S - - - PQQ-like domain
HGBEPDGP_04087 7.22e-79 - - - S - - - Family of unknown function (DUF5391)
HGBEPDGP_04088 4.03e-99 yxaI - - S - - - membrane protein domain
HGBEPDGP_04089 4.89e-282 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
HGBEPDGP_04090 1.22e-249 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
HGBEPDGP_04091 1.59e-129 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
HGBEPDGP_04092 1.5e-255 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HGBEPDGP_04093 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HGBEPDGP_04094 5.1e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
HGBEPDGP_04095 2.19e-153 yxaC - - M - - - effector of murein hydrolase
HGBEPDGP_04096 1.79e-245 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
HGBEPDGP_04097 3.87e-262 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HGBEPDGP_04098 4.42e-164 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
HGBEPDGP_04099 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HGBEPDGP_04100 2.91e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
HGBEPDGP_04101 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HGBEPDGP_04102 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
HGBEPDGP_04103 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
HGBEPDGP_04104 5.52e-238 - - - S - - - Polysaccharide pyruvyl transferase
HGBEPDGP_04105 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HGBEPDGP_04106 7.55e-44 - 2.7.1.199 - G ko:K02777,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system
HGBEPDGP_04107 6.34e-165 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
HGBEPDGP_04108 1.44e-24 - - - - - - - -
HGBEPDGP_04109 5.49e-152 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HGBEPDGP_04110 8.4e-143 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HGBEPDGP_04111 1.22e-170 - - - O ko:K16922 - ko00000,ko01002 Peptidase M50
HGBEPDGP_04112 7.8e-237 - - - S - - - Radical SAM superfamily
HGBEPDGP_04113 1.99e-17 - - - - - - - -
HGBEPDGP_04114 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
HGBEPDGP_04116 5e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HGBEPDGP_04118 2.24e-87 - - - - - - - -
HGBEPDGP_04119 4.27e-296 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HGBEPDGP_04121 2.24e-41 yycQ - - S - - - Protein of unknown function (DUF2651)
HGBEPDGP_04122 1.17e-270 yycP - - - - - - -
HGBEPDGP_04123 1.68e-169 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HGBEPDGP_04124 5.25e-111 yycN - - K - - - Acetyltransferase
HGBEPDGP_04125 1.06e-239 - - - S - - - aspartate phosphatase
HGBEPDGP_04127 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
HGBEPDGP_04128 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HGBEPDGP_04129 9.1e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
HGBEPDGP_04130 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HGBEPDGP_04131 3.51e-212 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
HGBEPDGP_04132 6.75e-122 - - - K ko:K02483 - ko00000,ko02022 PFAM response regulator receiver
HGBEPDGP_04133 3.28e-98 - - - S - - - Peptidase propeptide and YPEB domain
HGBEPDGP_04134 2.2e-42 - - - S - - - Peptidase propeptide and YPEB domain
HGBEPDGP_04135 1.56e-277 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HGBEPDGP_04136 1.15e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HGBEPDGP_04137 2.83e-199 yycI - - S - - - protein conserved in bacteria
HGBEPDGP_04138 0.0 yycH - - S - - - protein conserved in bacteria
HGBEPDGP_04139 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HGBEPDGP_04140 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGBEPDGP_04145 1.29e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HGBEPDGP_04146 3.85e-98 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGBEPDGP_04147 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HGBEPDGP_04148 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
HGBEPDGP_04150 1.89e-22 yycC - - K - - - YycC-like protein
HGBEPDGP_04151 4.19e-283 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
HGBEPDGP_04152 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HGBEPDGP_04153 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
HGBEPDGP_04154 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
HGBEPDGP_04155 8.66e-204 yybS - - S - - - membrane
HGBEPDGP_04157 2.89e-110 cotF - - M ko:K06329 - ko00000 Spore coat protein
HGBEPDGP_04158 1.35e-89 yybR - - K - - - Transcriptional regulator
HGBEPDGP_04159 4.89e-210 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
HGBEPDGP_04160 3.19e-90 - - - - - - - -
HGBEPDGP_04162 1.01e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HGBEPDGP_04163 1.46e-140 - - - K - - - TipAS antibiotic-recognition domain
HGBEPDGP_04164 2.05e-183 - - - - - - - -
HGBEPDGP_04165 2.49e-87 - - - S - - - SnoaL-like domain
HGBEPDGP_04166 5.67e-162 yybG - - S - - - Pentapeptide repeat-containing protein
HGBEPDGP_04167 8.32e-275 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HGBEPDGP_04168 1.31e-210 yybE - - K - - - Transcriptional regulator
HGBEPDGP_04169 1.26e-100 yjcF - - S - - - Acetyltransferase (GNAT) domain
HGBEPDGP_04170 1.94e-94 yybC - - - - - - -
HGBEPDGP_04171 2.52e-163 - - - S - - - Metallo-beta-lactamase superfamily
HGBEPDGP_04172 4.54e-100 yybA - - K - - - transcriptional
HGBEPDGP_04173 2.85e-93 yjcF - - S - - - Acetyltransferase (GNAT) domain
HGBEPDGP_04174 1.74e-124 yyaS - - S ko:K07149 - ko00000 Membrane
HGBEPDGP_04175 2.72e-119 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
HGBEPDGP_04176 1.5e-85 - - - S - - - YjbR
HGBEPDGP_04177 8.62e-137 yyaP - - H - - - RibD C-terminal domain
HGBEPDGP_04178 0.0 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
HGBEPDGP_04179 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
HGBEPDGP_04180 4.94e-214 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
HGBEPDGP_04181 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
HGBEPDGP_04182 1.55e-128 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
HGBEPDGP_04183 9.85e-88 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGBEPDGP_04184 1.29e-198 ccpB - - K - - - Transcriptional regulator
HGBEPDGP_04185 4.68e-184 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HGBEPDGP_04186 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HGBEPDGP_04187 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HGBEPDGP_04188 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HGBEPDGP_04189 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HGBEPDGP_04190 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HGBEPDGP_04191 7.41e-45 yyzM - - S - - - protein conserved in bacteria
HGBEPDGP_04192 5.34e-227 yyaD - - S - - - Membrane
HGBEPDGP_04193 1.3e-144 yyaC - - S - - - Sporulation protein YyaC
HGBEPDGP_04194 1.32e-189 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HGBEPDGP_04195 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
HGBEPDGP_04196 9.26e-98 - - - S - - - Bacterial PH domain
HGBEPDGP_04197 2.58e-192 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HGBEPDGP_04198 5.86e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HGBEPDGP_04199 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HGBEPDGP_04200 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HGBEPDGP_04201 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
HGBEPDGP_04202 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HGBEPDGP_04203 5.7e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)