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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HAPGDBDF_00001	4.62e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HAPGDBDF_00002	3.74e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HAPGDBDF_00003	1.55e-158	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HAPGDBDF_00004	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HAPGDBDF_00005	2.26e-306	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
HAPGDBDF_00006	2.26e-171	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HAPGDBDF_00007	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HAPGDBDF_00008	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HAPGDBDF_00009	1.31e-143	-	-	-	S	-	-	-	Cell surface protein
HAPGDBDF_00010	1.29e-210	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HAPGDBDF_00012	0.0	-	-	-	-	-	-	-	-
HAPGDBDF_00013	2.76e-141	sip3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HAPGDBDF_00015	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HAPGDBDF_00016	1.67e-79	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
HAPGDBDF_00017	4.69e-202	degV1	-	-	S	-	-	-	DegV family
HAPGDBDF_00018	3.66e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HAPGDBDF_00019	6.11e-187	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HAPGDBDF_00020	2.71e-135	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HAPGDBDF_00021	7.43e-130	padR	-	-	K	-	-	-	Virulence activator alpha C-term
HAPGDBDF_00022	2.51e-103	-	-	-	T	-	-	-	Universal stress protein family
HAPGDBDF_00023	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HAPGDBDF_00024	4.04e-241	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HAPGDBDF_00025	7.82e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HAPGDBDF_00026	4.99e-88	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HAPGDBDF_00027	2.53e-209	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
HAPGDBDF_00028	1.56e-185	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
HAPGDBDF_00029	2.85e-306	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HAPGDBDF_00030	7.7e-226	-	-	-	L	ko:K07482	-	ko00000	Integrase core domain
HAPGDBDF_00031	2.28e-115	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HAPGDBDF_00032	3.33e-113	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
HAPGDBDF_00033	1.23e-129	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
HAPGDBDF_00034	5.88e-233	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
HAPGDBDF_00035	6.96e-83	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HAPGDBDF_00036	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HAPGDBDF_00037	5.03e-95	-	-	-	K	-	-	-	Transcriptional regulator
HAPGDBDF_00038	0.0	pox4	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HAPGDBDF_00039	4.64e-255	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HAPGDBDF_00041	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
HAPGDBDF_00042	1.51e-85	-	-	-	KOT	ko:K07813	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01002	May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
HAPGDBDF_00043	9.62e-19	-	-	-	-	-	-	-	-
HAPGDBDF_00044	2.18e-211	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HAPGDBDF_00045	7.42e-174	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HAPGDBDF_00046	1.32e-101	nrp	-	-	K	ko:K16509	-	ko00000	ArsC family
HAPGDBDF_00047	0.0	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
HAPGDBDF_00048	1.96e-21	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
HAPGDBDF_00049	1.06e-16	-	-	-	-	-	-	-	-
HAPGDBDF_00050	2.1e-116	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HAPGDBDF_00051	2.43e-91	-	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
HAPGDBDF_00052	2.28e-291	-	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
HAPGDBDF_00053	2.13e-159	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HAPGDBDF_00054	1.86e-210	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
HAPGDBDF_00055	4.66e-197	nanK	-	-	GK	-	-	-	ROK family
HAPGDBDF_00056	9.03e-173	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HAPGDBDF_00057	4.01e-263	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HAPGDBDF_00058	0.0	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HAPGDBDF_00059	3.89e-205	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HAPGDBDF_00060	7.3e-210	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HAPGDBDF_00061	6.47e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HAPGDBDF_00062	3.8e-223	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HAPGDBDF_00063	3.76e-180	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HAPGDBDF_00064	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HAPGDBDF_00065	1.83e-146	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
HAPGDBDF_00066	3.99e-106	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HAPGDBDF_00067	6e-60	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HAPGDBDF_00068	8.37e-296	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HAPGDBDF_00069	5.26e-247	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
HAPGDBDF_00070	9.14e-146	gph3	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HAPGDBDF_00071	0.0	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HAPGDBDF_00072	1.58e-101	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HAPGDBDF_00073	7.29e-61	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system galactitol-specific IIB component
HAPGDBDF_00074	3.35e-305	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HAPGDBDF_00075	1.02e-147	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HAPGDBDF_00076	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HAPGDBDF_00077	1.74e-184	yxeH	-	-	S	-	-	-	hydrolase
HAPGDBDF_00078	1.91e-235	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HAPGDBDF_00080	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HAPGDBDF_00081	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HAPGDBDF_00082	1.08e-221	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
HAPGDBDF_00083	0.0	treP	2.4.1.64	GH65	G	ko:K05342	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HAPGDBDF_00084	4.12e-108	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HAPGDBDF_00085	6.59e-75	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HAPGDBDF_00086	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HAPGDBDF_00087	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HAPGDBDF_00088	0.0	pbg9	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HAPGDBDF_00089	3.72e-200	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HAPGDBDF_00090	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HAPGDBDF_00091	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HAPGDBDF_00092	2.74e-88	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HAPGDBDF_00093	3.13e-99	-	-	-	L	-	-	-	Transposase DDE domain
HAPGDBDF_00094	2.26e-269	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HAPGDBDF_00095	2.4e-202	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
HAPGDBDF_00096	5.07e-211	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HAPGDBDF_00097	4.67e-316	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HAPGDBDF_00098	5.44e-174	-	-	-	K	-	-	-	UTRA domain
HAPGDBDF_00099	2.63e-200	estA	-	-	S	-	-	-	Putative esterase
HAPGDBDF_00100	4.93e-82	-	-	-	-	-	-	-	-
HAPGDBDF_00101	1.12e-262	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HAPGDBDF_00102	1.73e-215	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HAPGDBDF_00103	5.56e-212	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HAPGDBDF_00104	1.64e-202	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HAPGDBDF_00105	8.13e-206	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HAPGDBDF_00106	1.71e-207	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HAPGDBDF_00107	1.4e-282	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HAPGDBDF_00108	4.62e-224	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HAPGDBDF_00109	1.12e-212	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HAPGDBDF_00110	3.65e-172	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HAPGDBDF_00111	1.23e-228	apbE3	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HAPGDBDF_00112	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HAPGDBDF_00113	2.02e-85	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
HAPGDBDF_00114	8.93e-249	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HAPGDBDF_00115	3.69e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HAPGDBDF_00116	4.27e-253	galM3	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HAPGDBDF_00117	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HAPGDBDF_00118	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HAPGDBDF_00119	1.64e-238	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HAPGDBDF_00120	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HAPGDBDF_00121	1.65e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HAPGDBDF_00122	1.26e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HAPGDBDF_00123	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HAPGDBDF_00124	1.19e-234	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HAPGDBDF_00125	3.4e-100	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HAPGDBDF_00126	6.22e-140	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HAPGDBDF_00127	1.29e-235	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HAPGDBDF_00128	5.06e-298	-	-	-	P	ko:K06610	-	ko00000,ko02000	Major Facilitator Superfamily
HAPGDBDF_00129	0.0	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HAPGDBDF_00130	5.02e-294	-	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
HAPGDBDF_00131	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HAPGDBDF_00132	1.13e-228	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
HAPGDBDF_00133	8.86e-298	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HAPGDBDF_00134	2.81e-90	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HAPGDBDF_00135	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HAPGDBDF_00136	5.67e-212	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HAPGDBDF_00137	4.18e-282	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HAPGDBDF_00138	4.67e-250	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HAPGDBDF_00139	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HAPGDBDF_00140	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HAPGDBDF_00141	1.95e-140	aqpZ	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HAPGDBDF_00142	3.31e-282	-	-	-	S	-	-	-	associated with various cellular activities
HAPGDBDF_00143	4.67e-316	-	-	-	S	-	-	-	Putative metallopeptidase domain
HAPGDBDF_00144	1.03e-65	-	-	-	-	-	-	-	-
HAPGDBDF_00145	8.19e-134	yezE	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
HAPGDBDF_00146	7.83e-60	-	-	-	-	-	-	-	-
HAPGDBDF_00147	4.23e-129	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HAPGDBDF_00148	1.44e-158	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HAPGDBDF_00149	1.83e-235	-	-	-	S	-	-	-	Cell surface protein
HAPGDBDF_00150	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HAPGDBDF_00151	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HAPGDBDF_00152	5.23e-107	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HAPGDBDF_00153	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HAPGDBDF_00154	1.82e-152	rcfA	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HAPGDBDF_00155	2.98e-44	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
HAPGDBDF_00156	1.74e-125	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HAPGDBDF_00157	1.01e-26	-	-	-	-	-	-	-	-
HAPGDBDF_00158	4.82e-55	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
HAPGDBDF_00159	2.34e-72	trxA3	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
HAPGDBDF_00160	2.71e-182	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HAPGDBDF_00161	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HAPGDBDF_00162	1.98e-232	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HAPGDBDF_00163	1.5e-165	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
HAPGDBDF_00164	3.42e-174	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HAPGDBDF_00165	2.07e-154	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HAPGDBDF_00166	7.46e-35	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HAPGDBDF_00167	1.12e-134	-	-	-	K	-	-	-	transcriptional regulator
HAPGDBDF_00169	9.39e-84	-	-	-	-	-	-	-	-
HAPGDBDF_00171	5.77e-81	-	-	-	-	-	-	-	-
HAPGDBDF_00172	6.18e-71	-	-	-	-	-	-	-	-
HAPGDBDF_00173	2.75e-96	-	-	-	M	-	-	-	PFAM NLP P60 protein
HAPGDBDF_00174	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
HAPGDBDF_00175	4.45e-38	-	-	-	-	-	-	-	-
HAPGDBDF_00176	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HAPGDBDF_00177	3.81e-150	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAPGDBDF_00178	5.33e-114	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HAPGDBDF_00179	2.74e-175	yesN	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HAPGDBDF_00180	5.48e-171	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HAPGDBDF_00181	6.48e-244	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HAPGDBDF_00182	0.0	-	-	-	-	-	-	-	-
HAPGDBDF_00183	1.39e-211	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HAPGDBDF_00184	1.58e-66	-	-	-	-	-	-	-	-
HAPGDBDF_00185	6.47e-124	-	-	-	K	ko:K22041	-	ko00000,ko03000	transcriptional regulator
HAPGDBDF_00186	5.94e-118	ymdB	-	-	S	-	-	-	Macro domain protein
HAPGDBDF_00187	2.69e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HAPGDBDF_00188	1.5e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HAPGDBDF_00189	1.7e-101	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HAPGDBDF_00190	2.57e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
HAPGDBDF_00191	1.12e-208	yvgN	-	-	C	-	-	-	Aldo keto reductase
HAPGDBDF_00193	8.84e-182	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HAPGDBDF_00194	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HAPGDBDF_00195	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HAPGDBDF_00196	1.14e-110	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HAPGDBDF_00197	6.1e-101	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HAPGDBDF_00198	5.99e-231	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HAPGDBDF_00199	1.77e-282	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HAPGDBDF_00200	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HAPGDBDF_00201	5.07e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF1398)
HAPGDBDF_00202	2.55e-65	-	-	-	-	-	-	-	-
HAPGDBDF_00203	7.21e-35	-	-	-	-	-	-	-	-
HAPGDBDF_00204	7e-208	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HAPGDBDF_00205	2.22e-169	-	-	-	L	-	-	-	Helix-turn-helix domain
HAPGDBDF_00206	8.8e-315	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HAPGDBDF_00207	3.43e-96	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
HAPGDBDF_00208	4.26e-54	-	-	-	-	-	-	-	-
HAPGDBDF_00209	8.01e-97	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HAPGDBDF_00210	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HAPGDBDF_00211	4.38e-243	pva2	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HAPGDBDF_00212	1.47e-144	-	-	-	S	-	-	-	VIT family
HAPGDBDF_00213	2.66e-155	-	-	-	S	-	-	-	membrane
HAPGDBDF_00214	9.43e-203	-	-	-	EG	-	-	-	EamA-like transporter family
HAPGDBDF_00215	2.52e-107	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HAPGDBDF_00216	3.57e-150	-	-	-	GM	-	-	-	NmrA-like family
HAPGDBDF_00217	4.79e-21	-	-	-	-	-	-	-	-
HAPGDBDF_00218	3.78e-73	-	-	-	-	-	-	-	-
HAPGDBDF_00219	4.58e-103	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HAPGDBDF_00220	1.36e-112	-	-	-	-	-	-	-	-
HAPGDBDF_00221	1.22e-81	-	-	-	-	-	-	-	-
HAPGDBDF_00222	4.98e-275	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
HAPGDBDF_00223	1.7e-70	-	-	-	-	-	-	-	-
HAPGDBDF_00224	3.46e-87	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HAPGDBDF_00225	9.97e-94	spxA	-	-	P	ko:K16509	-	ko00000	ArsC family
HAPGDBDF_00226	2.14e-86	-	-	-	K	ko:K22296	-	ko00000,ko03000	Winged helix DNA-binding domain
HAPGDBDF_00227	6.47e-208	-	-	-	GM	-	-	-	NmrA-like family
HAPGDBDF_00228	4.75e-112	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
HAPGDBDF_00229	4.58e-216	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HAPGDBDF_00230	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HAPGDBDF_00231	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HAPGDBDF_00232	3.58e-36	-	-	-	S	-	-	-	Belongs to the LOG family
HAPGDBDF_00233	7.12e-256	glmS2	-	-	M	-	-	-	SIS domain
HAPGDBDF_00234	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HAPGDBDF_00235	3.05e-281	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HAPGDBDF_00236	2.32e-160	-	-	-	S	-	-	-	YjbR
HAPGDBDF_00238	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HAPGDBDF_00239	0.0	-	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
HAPGDBDF_00240	8.79e-156	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HAPGDBDF_00241	4.29e-101	-	-	-	-	-	-	-	-
HAPGDBDF_00242	9.9e-49	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HAPGDBDF_00243	2.42e-127	-	-	-	FG	-	-	-	HIT domain
HAPGDBDF_00244	6.07e-223	ydhF	-	-	S	-	-	-	Aldo keto reductase
HAPGDBDF_00245	8.93e-71	-	-	-	S	-	-	-	Pfam:DUF59
HAPGDBDF_00246	1.12e-206	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HAPGDBDF_00247	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HAPGDBDF_00248	1.26e-247	-	-	-	V	-	-	-	Beta-lactamase
HAPGDBDF_00249	3.74e-125	-	-	-	V	-	-	-	VanZ like family
HAPGDBDF_00250	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HAPGDBDF_00251	4.54e-54	-	-	-	-	-	-	-	-
HAPGDBDF_00253	8.83e-317	-	-	-	EGP	-	-	-	Major Facilitator
HAPGDBDF_00254	5.61e-216	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HAPGDBDF_00255	4.08e-107	cvpA	-	-	S	-	-	-	Colicin V production protein
HAPGDBDF_00256	9.61e-84	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HAPGDBDF_00257	1.59e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HAPGDBDF_00258	1.04e-133	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HAPGDBDF_00259	5.04e-315	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HAPGDBDF_00260	3.59e-130	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HAPGDBDF_00261	1.37e-271	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
HAPGDBDF_00262	1.31e-122	tag2	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HAPGDBDF_00263	8.03e-28	-	-	-	-	-	-	-	-
HAPGDBDF_00265	6.62e-133	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HAPGDBDF_00266	1.3e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HAPGDBDF_00267	7.27e-73	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HAPGDBDF_00268	2.94e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HAPGDBDF_00269	1.97e-60	qacH	-	-	U	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HAPGDBDF_00270	1.15e-77	-	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HAPGDBDF_00271	1.68e-276	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HAPGDBDF_00272	1.54e-228	ydbI	-	-	K	-	-	-	AI-2E family transporter
HAPGDBDF_00273	1.07e-211	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HAPGDBDF_00274	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HAPGDBDF_00276	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
HAPGDBDF_00277	4.62e-107	-	-	-	-	-	-	-	-
HAPGDBDF_00279	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HAPGDBDF_00280	5.9e-187	ptp2	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HAPGDBDF_00281	0.0	amiA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HAPGDBDF_00282	0.0	amiC	-	-	U	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAPGDBDF_00283	2.53e-200	-	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HAPGDBDF_00284	1.84e-241	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HAPGDBDF_00285	4.29e-33	amiF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HAPGDBDF_00286	6.97e-134	amiF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HAPGDBDF_00287	4.17e-235	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HAPGDBDF_00288	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HAPGDBDF_00289	3.66e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HAPGDBDF_00290	2.05e-72	-	-	-	S	-	-	-	Enterocin A Immunity
HAPGDBDF_00291	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HAPGDBDF_00292	1.01e-251	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HAPGDBDF_00293	4.68e-235	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
HAPGDBDF_00294	6.72e-209	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
HAPGDBDF_00295	0.0	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
HAPGDBDF_00296	1.48e-152	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
HAPGDBDF_00297	4.22e-34	-	-	-	-	-	-	-	-
HAPGDBDF_00298	3.84e-186	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HAPGDBDF_00299	2.88e-164	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
HAPGDBDF_00300	9.76e-83	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
HAPGDBDF_00301	2.8e-135	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HAPGDBDF_00302	1.29e-31	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HAPGDBDF_00303	4.05e-170	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HAPGDBDF_00304	6.46e-49	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
HAPGDBDF_00305	3.07e-284	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HAPGDBDF_00306	1.23e-53	-	-	-	S	-	-	-	Enterocin A Immunity
HAPGDBDF_00307	1.55e-114	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HAPGDBDF_00308	1.78e-139	-	-	-	-	-	-	-	-
HAPGDBDF_00309	3.43e-303	-	-	-	S	-	-	-	module of peptide synthetase
HAPGDBDF_00310	8.66e-130	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HAPGDBDF_00312	5.08e-164	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
HAPGDBDF_00313	0.0	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HAPGDBDF_00314	7.54e-200	-	-	-	GM	-	-	-	NmrA-like family
HAPGDBDF_00315	4.08e-101	-	-	-	K	-	-	-	MerR family regulatory protein
HAPGDBDF_00316	2.11e-104	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HAPGDBDF_00317	5.55e-22	-	-	-	G	ko:K11203	-	ko00000,ko00002,ko02000	PTS system, fructose subfamily
HAPGDBDF_00318	2.52e-35	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HAPGDBDF_00319	6.69e-155	fptC	-	-	U	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase system, EIIC
HAPGDBDF_00320	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
HAPGDBDF_00321	2.24e-116	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HAPGDBDF_00322	3.54e-190	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HAPGDBDF_00323	2.69e-194	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
HAPGDBDF_00324	6.26e-101	-	-	-	-	-	-	-	-
HAPGDBDF_00325	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HAPGDBDF_00326	2.93e-151	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HAPGDBDF_00327	2.44e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HAPGDBDF_00328	3.73e-263	-	-	-	S	-	-	-	DUF218 domain
HAPGDBDF_00329	6.12e-232	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HAPGDBDF_00330	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HAPGDBDF_00331	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HAPGDBDF_00332	1.13e-200	-	-	-	S	-	-	-	Putative adhesin
HAPGDBDF_00333	1.73e-132	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HAPGDBDF_00334	2.86e-68	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
HAPGDBDF_00335	1.07e-127	-	-	-	KT	-	-	-	response to antibiotic
HAPGDBDF_00336	1.26e-161	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HAPGDBDF_00337	3.02e-176	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HAPGDBDF_00338	2.11e-158	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HAPGDBDF_00339	2.13e-167	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HAPGDBDF_00340	2.07e-302	-	-	-	EK	-	-	-	Aminotransferase, class I
HAPGDBDF_00341	3.36e-216	-	-	-	K	-	-	-	LysR substrate binding domain
HAPGDBDF_00342	1.49e-188	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HAPGDBDF_00343	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HAPGDBDF_00344	1.66e-288	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
HAPGDBDF_00345	1.81e-168	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HAPGDBDF_00346	8.63e-191	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HAPGDBDF_00347	1.01e-175	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HAPGDBDF_00348	7.16e-201	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HAPGDBDF_00349	1.4e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HAPGDBDF_00350	6.6e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HAPGDBDF_00351	3.49e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HAPGDBDF_00352	3.49e-270	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HAPGDBDF_00353	3.3e-208	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HAPGDBDF_00354	1.39e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HAPGDBDF_00355	1.14e-159	vanR	-	-	K	-	-	-	response regulator
HAPGDBDF_00356	5.61e-273	hpk31	-	-	T	-	-	-	Histidine kinase
HAPGDBDF_00357	3.61e-303	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HAPGDBDF_00358	6.77e-116	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HAPGDBDF_00359	4.83e-166	-	-	-	E	-	-	-	branched-chain amino acid
HAPGDBDF_00360	5.93e-73	-	-	-	S	-	-	-	branched-chain amino acid
HAPGDBDF_00361	3.37e-141	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HAPGDBDF_00362	5.94e-40	-	-	-	-	-	-	-	-
HAPGDBDF_00363	3.33e-89	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HAPGDBDF_00364	3.13e-99	-	-	-	L	-	-	-	Transposase DDE domain
HAPGDBDF_00365	5.61e-98	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGDBDF_00366	2.47e-125	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HAPGDBDF_00367	9.58e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
HAPGDBDF_00368	1.86e-256	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
HAPGDBDF_00369	3.32e-210	-	-	-	-	-	-	-	-
HAPGDBDF_00370	3.66e-295	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HAPGDBDF_00371	2.92e-143	-	-	-	-	-	-	-	-
HAPGDBDF_00372	9.28e-271	xylR	-	-	GK	-	-	-	ROK family
HAPGDBDF_00373	1.6e-233	ydbI	-	-	K	-	-	-	AI-2E family transporter
HAPGDBDF_00374	5.06e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HAPGDBDF_00375	6.79e-53	-	-	-	-	-	-	-	-
HAPGDBDF_00376	7.85e-114	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HAPGDBDF_00377	2.5e-66	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HAPGDBDF_00378	1.92e-115	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HAPGDBDF_00379	2e-62	-	-	-	K	-	-	-	Helix-turn-helix domain
HAPGDBDF_00380	5.09e-283	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HAPGDBDF_00381	2.33e-56	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HAPGDBDF_00382	1.31e-139	yoaZ	-	-	S	-	-	-	intracellular protease amidase
HAPGDBDF_00383	1.04e-59	-	-	-	S	-	-	-	Protein of unknown function (DUF3781)
HAPGDBDF_00384	2.23e-279	-	-	-	S	-	-	-	Membrane
HAPGDBDF_00385	5.98e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HAPGDBDF_00386	4.83e-31	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HAPGDBDF_00387	5.61e-54	pcaC	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HAPGDBDF_00388	5.15e-16	-	-	-	-	-	-	-	-
HAPGDBDF_00389	2.09e-85	-	-	-	-	-	-	-	-
HAPGDBDF_00390	7.36e-316	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HAPGDBDF_00391	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HAPGDBDF_00392	1.9e-148	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HAPGDBDF_00393	9.82e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HAPGDBDF_00394	0.0	-	-	-	S	-	-	-	MucBP domain
HAPGDBDF_00395	2.5e-180	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HAPGDBDF_00396	3.05e-144	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HAPGDBDF_00397	1.06e-205	-	-	-	K	-	-	-	LysR substrate binding domain
HAPGDBDF_00398	1.07e-200	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
HAPGDBDF_00399	0.0	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HAPGDBDF_00400	0.0	lepA2	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HAPGDBDF_00401	6.88e-152	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAPGDBDF_00402	1.6e-261	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HAPGDBDF_00403	1.1e-115	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HAPGDBDF_00404	3.25e-96	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HAPGDBDF_00405	1.07e-115	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HAPGDBDF_00406	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HAPGDBDF_00407	6.41e-84	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HAPGDBDF_00408	1.5e-193	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HAPGDBDF_00409	4.01e-96	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HAPGDBDF_00410	2.47e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HAPGDBDF_00411	7.95e-201	-	-	-	GM	-	-	-	NmrA-like family
HAPGDBDF_00412	3.74e-120	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAPGDBDF_00413	7.82e-218	fhuG	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HAPGDBDF_00414	1.81e-228	fhuB	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HAPGDBDF_00415	2.6e-187	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HAPGDBDF_00416	3.35e-217	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HAPGDBDF_00417	7.57e-141	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAPGDBDF_00418	0.0	yfjF	-	-	U	-	-	-	Sugar (and other) transporter
HAPGDBDF_00419	1.33e-227	ydhF	-	-	S	-	-	-	Aldo keto reductase
HAPGDBDF_00420	1.09e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HAPGDBDF_00421	7.7e-226	-	-	-	L	ko:K07482	-	ko00000	Integrase core domain
HAPGDBDF_00422	3.47e-244	-	1.1.1.219	-	GM	ko:K00091	-	ko00000,ko01000	Male sterility protein
HAPGDBDF_00423	1.66e-125	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAPGDBDF_00424	3.27e-170	-	-	-	S	-	-	-	KR domain
HAPGDBDF_00425	1.27e-83	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HAPGDBDF_00426	1.62e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF1905)
HAPGDBDF_00427	1.23e-54	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HAPGDBDF_00428	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HAPGDBDF_00429	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HAPGDBDF_00430	6.24e-215	-	-	-	GM	-	-	-	NmrA-like family
HAPGDBDF_00431	1.03e-126	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAPGDBDF_00432	1.77e-282	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HAPGDBDF_00433	1.27e-170	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HAPGDBDF_00434	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HAPGDBDF_00435	7.81e-148	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HAPGDBDF_00436	1.81e-272	-	-	-	EGP	-	-	-	Major Facilitator
HAPGDBDF_00437	4.31e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HAPGDBDF_00438	4.13e-157	-	-	-	-	-	-	-	-
HAPGDBDF_00439	7.55e-303	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HAPGDBDF_00440	1.47e-83	-	-	-	-	-	-	-	-
HAPGDBDF_00441	2.7e-131	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HAPGDBDF_00442	7.66e-237	ynjC	-	-	S	-	-	-	Cell surface protein
HAPGDBDF_00443	3.89e-148	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HAPGDBDF_00444	1.27e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HAPGDBDF_00445	1.55e-224	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
HAPGDBDF_00446	3.48e-136	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HAPGDBDF_00447	5.14e-246	-	-	-	S	-	-	-	Cell surface protein
HAPGDBDF_00448	2.69e-99	-	-	-	-	-	-	-	-
HAPGDBDF_00449	0.0	-	-	-	-	-	-	-	-
HAPGDBDF_00450	3.05e-289	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HAPGDBDF_00451	1.47e-51	-	-	-	S	ko:K07343	-	ko00000	TfoX C-terminal domain
HAPGDBDF_00452	2.81e-181	-	-	-	K	-	-	-	Helix-turn-helix domain
HAPGDBDF_00453	0.0	aapA	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HAPGDBDF_00454	1.36e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
HAPGDBDF_00455	1.49e-58	-	-	-	S	-	-	-	Cupredoxin-like domain
HAPGDBDF_00456	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HAPGDBDF_00457	6.8e-272	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
HAPGDBDF_00458	7.48e-146	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HAPGDBDF_00459	5.54e-125	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HAPGDBDF_00460	1.67e-86	lysM	-	-	M	-	-	-	LysM domain
HAPGDBDF_00461	0.0	-	-	-	E	-	-	-	Amino Acid
HAPGDBDF_00462	2.47e-185	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HAPGDBDF_00463	1.21e-45	-	-	-	-	-	-	-	-
HAPGDBDF_00464	3.12e-36	-	-	-	-	-	-	-	-
HAPGDBDF_00466	2.96e-209	yhxD	-	-	IQ	-	-	-	KR domain
HAPGDBDF_00467	7.29e-287	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
HAPGDBDF_00468	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HAPGDBDF_00469	1.45e-97	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HAPGDBDF_00470	3.5e-308	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HAPGDBDF_00471	2.31e-277	-	-	-	-	-	-	-	-
HAPGDBDF_00472	2.4e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
HAPGDBDF_00473	3.83e-178	gdh	1.1.1.47, 1.1.1.53	-	IQ	ko:K00034,ko:K00038	ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200	ko00000,ko00001,ko01000	reductase
HAPGDBDF_00474	3.55e-79	-	-	-	I	-	-	-	sulfurtransferase activity
HAPGDBDF_00475	6.7e-102	yphH	-	-	S	-	-	-	Cupin domain
HAPGDBDF_00476	1.37e-119	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HAPGDBDF_00477	2.15e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
HAPGDBDF_00478	7.62e-222	-	-	-	C	-	-	-	C4-dicarboxylate transmembrane transporter activity
HAPGDBDF_00479	6.54e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HAPGDBDF_00480	5.26e-96	-	-	-	-	-	-	-	-
HAPGDBDF_00481	1.66e-214	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HAPGDBDF_00482	1.56e-56	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAPGDBDF_00483	1e-98	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
HAPGDBDF_00484	6.61e-77	-	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HAPGDBDF_00486	5.05e-280	-	-	-	L	ko:K07487	-	ko00000	Transposase
HAPGDBDF_00487	7.7e-226	-	-	-	L	ko:K07482	-	ko00000	Integrase core domain
HAPGDBDF_00488	1.04e-52	-	-	-	L	ko:K07487	-	ko00000	Transposase
HAPGDBDF_00489	1.91e-44	-	-	-	C	-	-	-	Flavodoxin
HAPGDBDF_00490	7.53e-102	-	-	-	GM	-	-	-	NmrA-like family
HAPGDBDF_00491	2.62e-173	-	-	-	C	-	-	-	Aldo/keto reductase family
HAPGDBDF_00492	1.2e-208	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
HAPGDBDF_00493	1.58e-47	-	-	-	C	-	-	-	Flavodoxin
HAPGDBDF_00494	1e-62	adhR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HAPGDBDF_00495	5.36e-38	-	-	-	-	-	-	-	-
HAPGDBDF_00496	6.88e-151	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HAPGDBDF_00497	1.43e-57	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HAPGDBDF_00498	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HAPGDBDF_00499	4.65e-91	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGDBDF_00500	1.22e-272	-	-	-	T	-	-	-	diguanylate cyclase
HAPGDBDF_00501	6.68e-156	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
HAPGDBDF_00502	1.41e-118	-	-	-	-	-	-	-	-
HAPGDBDF_00503	2.74e-210	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HAPGDBDF_00504	1.58e-72	nudA	-	-	S	-	-	-	ASCH
HAPGDBDF_00505	1.4e-138	-	-	-	S	-	-	-	SdpI/YhfL protein family
HAPGDBDF_00506	1.44e-128	-	-	-	M	-	-	-	Lysin motif
HAPGDBDF_00507	2.18e-99	-	-	-	M	-	-	-	LysM domain
HAPGDBDF_00508	2.1e-99	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HAPGDBDF_00509	7.8e-238	-	-	-	GM	-	-	-	Male sterility protein
HAPGDBDF_00510	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HAPGDBDF_00511	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HAPGDBDF_00512	7.47e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HAPGDBDF_00513	3.91e-100	pts23A	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HAPGDBDF_00514	1.24e-194	-	-	-	K	-	-	-	Helix-turn-helix domain
HAPGDBDF_00515	1.21e-73	-	-	-	-	-	-	-	-
HAPGDBDF_00516	1.93e-205	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HAPGDBDF_00517	2.03e-84	-	-	-	-	-	-	-	-
HAPGDBDF_00518	0.0	-	-	-	P	-	-	-	Concanavalin A-like lectin/glucanases superfamily
HAPGDBDF_00519	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HAPGDBDF_00520	7.89e-124	-	-	-	P	-	-	-	Cadmium resistance transporter
HAPGDBDF_00521	8.58e-65	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HAPGDBDF_00522	1.81e-150	-	-	-	S	-	-	-	SNARE associated Golgi protein
HAPGDBDF_00523	7.03e-62	-	-	-	-	-	-	-	-
HAPGDBDF_00524	1.18e-94	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
HAPGDBDF_00525	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HAPGDBDF_00526	1.39e-157	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HAPGDBDF_00527	2.88e-106	gtcA3	-	-	S	-	-	-	GtrA-like protein
HAPGDBDF_00528	6.9e-168	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
HAPGDBDF_00529	1.15e-43	-	-	-	-	-	-	-	-
HAPGDBDF_00531	1.04e-269	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HAPGDBDF_00532	9.73e-197	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HAPGDBDF_00533	1.88e-192	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HAPGDBDF_00534	1.74e-178	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
HAPGDBDF_00535	2.78e-158	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HAPGDBDF_00536	1.09e-42	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HAPGDBDF_00537	5.06e-82	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HAPGDBDF_00538	1.81e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HAPGDBDF_00539	7.93e-85	-	-	-	S	-	-	-	Cell surface protein
HAPGDBDF_00540	4.9e-39	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HAPGDBDF_00541	2.97e-51	-	-	-	L	-	-	-	Transposase DDE domain
HAPGDBDF_00542	5.09e-141	-	-	-	S	-	-	-	Cell surface protein
HAPGDBDF_00543	4.71e-81	-	-	-	-	-	-	-	-
HAPGDBDF_00544	0.0	-	-	-	-	-	-	-	-
HAPGDBDF_00545	8.49e-217	XK27_00670	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HAPGDBDF_00546	1.01e-198	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HAPGDBDF_00547	4.21e-150	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HAPGDBDF_00548	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HAPGDBDF_00549	3.29e-153	ydgI3	-	-	C	-	-	-	Nitroreductase family
HAPGDBDF_00550	2.21e-154	yceE	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HAPGDBDF_00551	5.1e-189	ccpB	-	-	K	-	-	-	lacI family
HAPGDBDF_00552	7.39e-121	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HAPGDBDF_00553	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HAPGDBDF_00554	9.86e-117	-	-	-	-	-	-	-	-
HAPGDBDF_00555	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
HAPGDBDF_00556	4.54e-208	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HAPGDBDF_00557	1.85e-51	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HAPGDBDF_00558	4.68e-141	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HAPGDBDF_00559	1.44e-226	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
HAPGDBDF_00560	3.03e-166	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HAPGDBDF_00561	8.08e-205	yicL	-	-	EG	-	-	-	EamA-like transporter family
HAPGDBDF_00562	6.55e-295	-	-	-	M	-	-	-	Collagen binding domain
HAPGDBDF_00563	0.0	-	-	-	I	-	-	-	acetylesterase activity
HAPGDBDF_00564	2.35e-231	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HAPGDBDF_00565	1.48e-171	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HAPGDBDF_00566	4.29e-50	-	-	-	-	-	-	-	-
HAPGDBDF_00568	1.61e-183	-	-	-	S	-	-	-	zinc-ribbon domain
HAPGDBDF_00569	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HAPGDBDF_00570	0.0	-	4.1.1.98	-	H	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HAPGDBDF_00571	4.34e-314	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HAPGDBDF_00572	3.46e-210	-	-	-	K	-	-	-	LysR substrate binding domain
HAPGDBDF_00573	1.84e-134	-	-	-	-	-	-	-	-
HAPGDBDF_00574	7.16e-30	-	-	-	-	-	-	-	-
HAPGDBDF_00575	1.26e-245	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HAPGDBDF_00576	1.03e-239	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HAPGDBDF_00577	6.98e-95	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HAPGDBDF_00578	1.56e-108	-	-	-	-	-	-	-	-
HAPGDBDF_00579	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HAPGDBDF_00580	3.83e-135	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HAPGDBDF_00581	1.63e-162	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HAPGDBDF_00582	5.08e-194	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HAPGDBDF_00583	1.11e-65	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HAPGDBDF_00584	8.68e-118	pts21A	-	-	G	ko:K02755	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HAPGDBDF_00585	2e-52	-	-	-	S	-	-	-	Cytochrome B5
HAPGDBDF_00586	0.0	-	-	-	-	-	-	-	-
HAPGDBDF_00587	6.11e-169	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HAPGDBDF_00588	2.85e-206	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HAPGDBDF_00589	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HAPGDBDF_00590	2.33e-296	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HAPGDBDF_00591	7.97e-222	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HAPGDBDF_00592	9.48e-265	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HAPGDBDF_00593	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
HAPGDBDF_00594	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HAPGDBDF_00595	1.9e-189	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HAPGDBDF_00596	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HAPGDBDF_00597	3.18e-282	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HAPGDBDF_00598	3.27e-171	-	-	-	M	-	-	-	Phosphotransferase enzyme family
HAPGDBDF_00599	1.24e-125	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HAPGDBDF_00600	1.34e-132	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HAPGDBDF_00601	4.88e-196	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HAPGDBDF_00602	6.88e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HAPGDBDF_00603	3.01e-124	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
HAPGDBDF_00604	1.03e-314	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HAPGDBDF_00608	6.27e-316	-	-	-	EGP	-	-	-	Major Facilitator
HAPGDBDF_00609	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HAPGDBDF_00610	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HAPGDBDF_00612	5.17e-249	-	-	-	C	-	-	-	Aldo/keto reductase family
HAPGDBDF_00613	1.07e-131	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HAPGDBDF_00614	2.33e-283	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HAPGDBDF_00615	5.29e-131	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HAPGDBDF_00616	2.31e-79	-	-	-	-	-	-	-	-
HAPGDBDF_00617	5.89e-161	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HAPGDBDF_00618	2.09e-124	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HAPGDBDF_00619	2.1e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HAPGDBDF_00620	1.28e-45	-	-	-	-	-	-	-	-
HAPGDBDF_00621	1.18e-193	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HAPGDBDF_00622	1.66e-247	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HAPGDBDF_00623	1.52e-135	-	-	-	GM	-	-	-	NAD(P)H-binding
HAPGDBDF_00624	6.13e-200	-	-	-	K	-	-	-	LysR substrate binding domain
HAPGDBDF_00625	6.09e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
HAPGDBDF_00626	7.44e-143	pgm8	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
HAPGDBDF_00627	2.81e-64	-	-	-	-	-	-	-	-
HAPGDBDF_00628	9.76e-50	-	-	-	-	-	-	-	-
HAPGDBDF_00629	1.04e-110	yvbK	-	-	K	-	-	-	GNAT family
HAPGDBDF_00630	4.86e-111	-	-	-	-	-	-	-	-
HAPGDBDF_00632	1.03e-150	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HAPGDBDF_00633	3.18e-141	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HAPGDBDF_00634	2.93e-151	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HAPGDBDF_00636	1.74e-156	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HAPGDBDF_00637	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HAPGDBDF_00638	1.46e-299	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HAPGDBDF_00639	5.19e-103	-	-	-	K	-	-	-	transcriptional regulator, MerR family
HAPGDBDF_00640	4.77e-100	yphH	-	-	S	-	-	-	Cupin domain
HAPGDBDF_00641	4.72e-72	cmd	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HAPGDBDF_00642	6.27e-166	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HAPGDBDF_00643	7.88e-269	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HAPGDBDF_00644	9.97e-214	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HAPGDBDF_00645	1.6e-119	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
HAPGDBDF_00646	9.92e-88	-	-	-	M	-	-	-	LysM domain
HAPGDBDF_00648	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HAPGDBDF_00649	0.0	tagE5	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
HAPGDBDF_00650	2.06e-194	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HAPGDBDF_00651	4.38e-222	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HAPGDBDF_00652	6.55e-126	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HAPGDBDF_00653	2.33e-103	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HAPGDBDF_00654	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HAPGDBDF_00655	1.99e-160	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HAPGDBDF_00656	3.04e-261	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HAPGDBDF_00657	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
HAPGDBDF_00658	3.49e-198	mleP3	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HAPGDBDF_00659	9.01e-155	-	-	-	S	-	-	-	Membrane
HAPGDBDF_00660	8.02e-258	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HAPGDBDF_00661	1.39e-124	ywjB	-	-	H	-	-	-	RibD C-terminal domain
HAPGDBDF_00662	8.13e-238	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HAPGDBDF_00663	2.27e-116	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
HAPGDBDF_00664	7.14e-157	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HAPGDBDF_00665	1.4e-239	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HAPGDBDF_00666	1.86e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HAPGDBDF_00667	3.41e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HAPGDBDF_00668	3.82e-188	-	-	-	KT	-	-	-	helix_turn_helix, mercury resistance
HAPGDBDF_00669	1.95e-149	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HAPGDBDF_00670	1.04e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HAPGDBDF_00671	9.06e-184	-	-	-	S	-	-	-	Peptidase_C39 like family
HAPGDBDF_00672	1.08e-229	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HAPGDBDF_00673	1.27e-143	-	-	-	-	-	-	-	-
HAPGDBDF_00674	3.47e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HAPGDBDF_00675	2.05e-110	-	-	-	S	-	-	-	Pfam:DUF3816
HAPGDBDF_00676	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HAPGDBDF_00678	6.19e-208	-	-	-	K	-	-	-	Transcriptional regulator
HAPGDBDF_00679	1.2e-206	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HAPGDBDF_00680	1.66e-211	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
HAPGDBDF_00681	2.45e-101	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HAPGDBDF_00682	0.0	ycaM	-	-	E	-	-	-	amino acid
HAPGDBDF_00683	2.38e-164	aroC1	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
HAPGDBDF_00684	4.3e-44	-	-	-	-	-	-	-	-
HAPGDBDF_00685	0.0	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HAPGDBDF_00686	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HAPGDBDF_00687	1.17e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HAPGDBDF_00688	0.0	-	-	-	-	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	-
HAPGDBDF_00689	3.78e-132	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HAPGDBDF_00690	4.12e-226	serA1	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HAPGDBDF_00691	2.25e-73	-	-	-	EG	-	-	-	EamA-like transporter family
HAPGDBDF_00692	1.2e-107	-	-	-	EG	-	-	-	EamA-like transporter family
HAPGDBDF_00693	2.05e-233	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HAPGDBDF_00694	5.06e-196	-	-	-	S	-	-	-	hydrolase
HAPGDBDF_00695	7.63e-107	-	-	-	-	-	-	-	-
HAPGDBDF_00696	1.75e-156	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
HAPGDBDF_00697	1.4e-181	epsV	-	-	S	-	-	-	glycosyl transferase family 2
HAPGDBDF_00698	6.37e-169	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HAPGDBDF_00699	1.86e-64	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HAPGDBDF_00700	6.7e-74	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
HAPGDBDF_00701	0.0	pbg5	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HAPGDBDF_00702	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HAPGDBDF_00703	9.53e-317	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HAPGDBDF_00704	8.66e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HAPGDBDF_00705	6.17e-255	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type multidrug transport system, permease component
HAPGDBDF_00706	1.44e-150	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAPGDBDF_00707	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HAPGDBDF_00708	7.54e-115	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
HAPGDBDF_00709	3.26e-262	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HAPGDBDF_00710	3.64e-293	-	-	-	S	-	-	-	Sterol carrier protein domain
HAPGDBDF_00711	9.97e-269	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HAPGDBDF_00712	3.94e-49	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
HAPGDBDF_00713	1.62e-173	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HAPGDBDF_00714	2.26e-91	-	-	-	FG	-	-	-	Scavenger mRNA decapping enzyme C-term binding
HAPGDBDF_00715	3.24e-132	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HAPGDBDF_00716	1.76e-143	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HAPGDBDF_00717	4.72e-40	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
HAPGDBDF_00718	1.33e-185	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HAPGDBDF_00719	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HAPGDBDF_00720	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HAPGDBDF_00721	1.21e-69	-	-	-	-	-	-	-	-
HAPGDBDF_00722	1.02e-149	-	-	-	-	-	-	-	-
HAPGDBDF_00723	1.16e-110	-	-	-	F	-	-	-	belongs to the nudix hydrolase family
HAPGDBDF_00724	8.32e-297	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HAPGDBDF_00725	4.79e-13	-	-	-	-	-	-	-	-
HAPGDBDF_00726	4.87e-66	-	-	-	-	-	-	-	-
HAPGDBDF_00727	1.76e-114	-	-	-	-	-	-	-	-
HAPGDBDF_00728	4.02e-95	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HAPGDBDF_00729	1.08e-47	-	-	-	-	-	-	-	-
HAPGDBDF_00730	2.7e-104	usp5	-	-	T	-	-	-	universal stress protein
HAPGDBDF_00731	3.41e-190	-	-	-	-	-	-	-	-
HAPGDBDF_00732	7.89e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HAPGDBDF_00733	8.2e-81	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HAPGDBDF_00734	4.76e-56	-	-	-	-	-	-	-	-
HAPGDBDF_00735	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HAPGDBDF_00736	8.34e-178	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HAPGDBDF_00737	3.7e-233	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HAPGDBDF_00738	4.15e-191	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HAPGDBDF_00739	3.44e-152	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
HAPGDBDF_00740	2.04e-189	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HAPGDBDF_00741	2.01e-243	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
HAPGDBDF_00742	9.92e-143	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HAPGDBDF_00743	7.9e-305	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HAPGDBDF_00744	3.77e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HAPGDBDF_00745	5.8e-270	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HAPGDBDF_00746	3.39e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HAPGDBDF_00747	1.17e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HAPGDBDF_00748	1.63e-162	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HAPGDBDF_00749	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HAPGDBDF_00750	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HAPGDBDF_00751	2.97e-243	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HAPGDBDF_00752	5.35e-133	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HAPGDBDF_00753	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HAPGDBDF_00754	9.06e-279	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HAPGDBDF_00755	6.93e-162	-	-	-	E	-	-	-	Methionine synthase
HAPGDBDF_00756	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HAPGDBDF_00757	3.73e-121	-	-	-	-	-	-	-	-
HAPGDBDF_00758	1.25e-199	-	-	-	T	-	-	-	EAL domain
HAPGDBDF_00759	2.24e-206	-	-	-	GM	-	-	-	NmrA-like family
HAPGDBDF_00760	5.67e-280	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
HAPGDBDF_00761	3.1e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HAPGDBDF_00762	0.0	pucR_2	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
HAPGDBDF_00763	7.13e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HAPGDBDF_00764	1.22e-220	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HAPGDBDF_00765	2.38e-310	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HAPGDBDF_00766	3.36e-272	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HAPGDBDF_00767	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HAPGDBDF_00768	1.04e-218	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HAPGDBDF_00769	1.55e-161	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HAPGDBDF_00770	6.64e-146	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HAPGDBDF_00771	9.44e-219	oroP	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
HAPGDBDF_00772	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HAPGDBDF_00773	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HAPGDBDF_00774	3.86e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HAPGDBDF_00775	1.29e-148	-	-	-	GM	-	-	-	NAD(P)H-binding
HAPGDBDF_00776	5.73e-208	mleR	-	-	K	-	-	-	LysR family
HAPGDBDF_00777	2.09e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HAPGDBDF_00778	3.59e-26	-	-	-	-	-	-	-	-
HAPGDBDF_00779	1.21e-183	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HAPGDBDF_00780	1.02e-277	araT2	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HAPGDBDF_00781	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	Bacterial regulatory proteins, gntR family
HAPGDBDF_00782	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HAPGDBDF_00783	4.71e-74	-	-	-	S	-	-	-	SdpI/YhfL protein family
HAPGDBDF_00784	1.27e-219	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HAPGDBDF_00785	4.71e-81	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HAPGDBDF_00786	2.03e-271	yttB	-	-	EGP	-	-	-	Major Facilitator
HAPGDBDF_00787	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HAPGDBDF_00788	1.18e-114	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HAPGDBDF_00789	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HAPGDBDF_00790	2.97e-76	-	-	-	-	-	-	-	-
HAPGDBDF_00791	2.61e-96	hsp2	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HAPGDBDF_00792	1.55e-79	-	-	-	-	-	-	-	-
HAPGDBDF_00793	1.7e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HAPGDBDF_00794	8.05e-179	rrp8	-	-	K	-	-	-	LytTr DNA-binding domain
HAPGDBDF_00795	4.85e-151	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HAPGDBDF_00796	1.74e-178	-	-	-	-	-	-	-	-
HAPGDBDF_00797	6.74e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HAPGDBDF_00798	3.53e-169	-	-	-	K	-	-	-	Transcriptional regulator
HAPGDBDF_00799	4.74e-208	-	-	-	S	-	-	-	Putative esterase
HAPGDBDF_00800	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HAPGDBDF_00801	5.31e-285	-	-	-	M	-	-	-	Glycosyl transferases group 1
HAPGDBDF_00802	1.38e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HAPGDBDF_00803	4.05e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HAPGDBDF_00804	8.5e-98	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HAPGDBDF_00805	1.09e-55	-	-	-	S	-	-	-	zinc-ribbon domain
HAPGDBDF_00806	3.77e-24	-	-	-	-	-	-	-	-
HAPGDBDF_00807	4.14e-202	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HAPGDBDF_00808	1.02e-102	uspA3	-	-	T	-	-	-	universal stress protein
HAPGDBDF_00809	5.87e-166	-	-	-	K	ko:K03710	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HAPGDBDF_00810	1.49e-112	-	2.7.1.191	-	K	ko:K02745,ko:K02794,ko:K10984	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HAPGDBDF_00811	5.2e-185	-	-	-	G	ko:K02746,ko:K10985	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HAPGDBDF_00812	3.82e-188	agaD	-	-	G	ko:K02747,ko:K02796,ko:K10986	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HAPGDBDF_00813	1.63e-95	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HAPGDBDF_00814	0.0	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
HAPGDBDF_00815	1e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HAPGDBDF_00816	4.15e-78	-	-	-	-	-	-	-	-
HAPGDBDF_00817	4.05e-98	-	-	-	-	-	-	-	-
HAPGDBDF_00818	6.94e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2798)
HAPGDBDF_00819	1.57e-71	-	-	-	-	-	-	-	-
HAPGDBDF_00820	3.89e-62	-	-	-	-	-	-	-	-
HAPGDBDF_00821	6.69e-263	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HAPGDBDF_00822	9.89e-74	ytpP	-	-	CO	-	-	-	Thioredoxin
HAPGDBDF_00823	1.97e-185	-	-	-	S	ko:K06889	-	ko00000	Dienelactone hydrolase family
HAPGDBDF_00824	5.82e-89	-	-	-	-	-	-	-	-
HAPGDBDF_00825	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HAPGDBDF_00826	4.83e-64	-	-	-	-	-	-	-	-
HAPGDBDF_00827	3.68e-77	-	-	-	-	-	-	-	-
HAPGDBDF_00829	2.64e-210	-	-	-	-	-	-	-	-
HAPGDBDF_00830	1.4e-95	-	-	-	K	-	-	-	Transcriptional regulator
HAPGDBDF_00831	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
HAPGDBDF_00832	4.62e-223	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HAPGDBDF_00833	7.2e-61	-	-	-	S	-	-	-	Enterocin A Immunity
HAPGDBDF_00834	8.34e-86	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
HAPGDBDF_00835	5e-162	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HAPGDBDF_00836	2.66e-172	-	-	-	-	-	-	-	-
HAPGDBDF_00837	9.38e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
HAPGDBDF_00838	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HAPGDBDF_00839	0.0	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HAPGDBDF_00840	8.97e-253	yhhX	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HAPGDBDF_00841	9.51e-49	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HAPGDBDF_00842	1.55e-49	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HAPGDBDF_00843	4.07e-217	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HAPGDBDF_00844	9.95e-92	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HAPGDBDF_00845	4.16e-150	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HAPGDBDF_00846	1.48e-201	ccpB	-	-	K	-	-	-	lacI family
HAPGDBDF_00847	2.2e-157	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HAPGDBDF_00848	2e-208	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HAPGDBDF_00849	1.23e-228	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HAPGDBDF_00850	2.57e-128	-	-	-	C	-	-	-	Nitroreductase family
HAPGDBDF_00851	6.04e-217	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HAPGDBDF_00852	2.35e-247	-	-	-	S	-	-	-	domain, Protein
HAPGDBDF_00853	2.14e-183	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HAPGDBDF_00854	4.01e-236	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HAPGDBDF_00855	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HAPGDBDF_00856	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HAPGDBDF_00857	3e-98	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HAPGDBDF_00858	0.0	-	-	-	M	-	-	-	domain protein
HAPGDBDF_00859	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HAPGDBDF_00860	1.26e-143	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HAPGDBDF_00861	1.45e-46	-	-	-	-	-	-	-	-
HAPGDBDF_00862	9.88e-239	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HAPGDBDF_00863	1.69e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HAPGDBDF_00864	4.54e-126	-	-	-	J	-	-	-	glyoxalase III activity
HAPGDBDF_00865	2.49e-190	-	-	-	GM	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HAPGDBDF_00866	4.73e-118	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
HAPGDBDF_00867	6.7e-74	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HAPGDBDF_00868	7.28e-213	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HAPGDBDF_00869	3.72e-283	ysaA	-	-	V	-	-	-	RDD family
HAPGDBDF_00870	3.2e-208	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
HAPGDBDF_00871	4.44e-273	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HAPGDBDF_00872	1.69e-151	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HAPGDBDF_00873	1.92e-299	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HAPGDBDF_00874	2.46e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HAPGDBDF_00875	2.23e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HAPGDBDF_00876	6.84e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HAPGDBDF_00877	1.27e-172	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HAPGDBDF_00878	6.12e-78	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HAPGDBDF_00879	1.07e-68	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
HAPGDBDF_00880	4.48e-257	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HAPGDBDF_00881	4.99e-125	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HAPGDBDF_00882	1.01e-176	yceF	-	-	P	ko:K05794	-	ko00000	membrane
HAPGDBDF_00883	9.51e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
HAPGDBDF_00884	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HAPGDBDF_00885	1.32e-178	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HAPGDBDF_00886	7.03e-195	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HAPGDBDF_00887	1.13e-225	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HAPGDBDF_00888	1.53e-213	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HAPGDBDF_00889	6.08e-312	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HAPGDBDF_00890	1.01e-293	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HAPGDBDF_00891	3.45e-209	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HAPGDBDF_00892	4.37e-241	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HAPGDBDF_00893	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HAPGDBDF_00894	9.2e-62	-	-	-	-	-	-	-	-
HAPGDBDF_00895	3.9e-105	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HAPGDBDF_00896	9.24e-140	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HAPGDBDF_00897	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HAPGDBDF_00898	6.37e-133	-	-	-	T	-	-	-	diguanylate cyclase
HAPGDBDF_00899	5.79e-126	-	-	-	T	-	-	-	diguanylate cyclase
HAPGDBDF_00900	1.11e-45	-	-	-	-	-	-	-	-
HAPGDBDF_00901	2.29e-48	-	-	-	-	-	-	-	-
HAPGDBDF_00902	5.92e-107	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
HAPGDBDF_00903	2.47e-222	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
HAPGDBDF_00904	2e-207	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HAPGDBDF_00906	2.68e-32	-	-	-	-	-	-	-	-
HAPGDBDF_00907	8.05e-178	-	-	-	F	-	-	-	NUDIX domain
HAPGDBDF_00908	6.83e-274	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
HAPGDBDF_00909	1.31e-64	-	-	-	-	-	-	-	-
HAPGDBDF_00910	6.24e-120	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HAPGDBDF_00912	1.26e-218	-	-	-	EG	-	-	-	EamA-like transporter family
HAPGDBDF_00913	2.49e-50	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HAPGDBDF_00914	2.12e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HAPGDBDF_00915	1.45e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HAPGDBDF_00916	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HAPGDBDF_00917	1.83e-277	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HAPGDBDF_00918	2.51e-200	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HAPGDBDF_00919	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HAPGDBDF_00920	2.1e-33	-	-	-	-	-	-	-	-
HAPGDBDF_00921	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HAPGDBDF_00922	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HAPGDBDF_00923	0.0	-	3.6.3.44	-	P	ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
HAPGDBDF_00924	4.63e-24	-	-	-	-	-	-	-	-
HAPGDBDF_00925	2.16e-26	-	-	-	-	-	-	-	-
HAPGDBDF_00926	9.35e-24	-	-	-	-	-	-	-	-
HAPGDBDF_00927	9.35e-24	-	-	-	-	-	-	-	-
HAPGDBDF_00928	1.07e-26	-	-	-	-	-	-	-	-
HAPGDBDF_00929	1.56e-22	-	-	-	-	-	-	-	-
HAPGDBDF_00930	3.26e-24	-	-	-	-	-	-	-	-
HAPGDBDF_00931	6.58e-24	-	-	-	-	-	-	-	-
HAPGDBDF_00932	0.0	inlJ	-	-	M	-	-	-	MucBP domain
HAPGDBDF_00933	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
HAPGDBDF_00934	1.27e-109	-	-	-	K	-	-	-	MarR family
HAPGDBDF_00935	1.09e-56	-	-	-	-	-	-	-	-
HAPGDBDF_00936	1.28e-51	-	-	-	-	-	-	-	-
HAPGDBDF_00937	2.54e-289	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPGDBDF_00938	1.1e-06	-	-	-	K	ko:K07727	-	ko00000,ko03000	transcriptional regulator
HAPGDBDF_00940	3.96e-13	-	-	-	-	-	-	-	-
HAPGDBDF_00942	3.18e-41	-	-	-	-	-	-	-	-
HAPGDBDF_00943	5.62e-183	-	-	-	L	-	-	-	DNA replication protein
HAPGDBDF_00944	0.0	-	-	-	S	-	-	-	Virulence-associated protein E
HAPGDBDF_00945	3.36e-96	-	-	-	-	-	-	-	-
HAPGDBDF_00947	7.63e-65	-	-	-	S	-	-	-	Head-tail joining protein
HAPGDBDF_00948	2.59e-89	-	-	-	L	-	-	-	HNH endonuclease
HAPGDBDF_00949	6.36e-108	-	-	-	L	-	-	-	overlaps another CDS with the same product name
HAPGDBDF_00950	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
HAPGDBDF_00951	0.000349	-	-	-	-	-	-	-	-
HAPGDBDF_00952	1.84e-261	-	-	-	S	-	-	-	Phage portal protein
HAPGDBDF_00953	0.0	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
HAPGDBDF_00954	1.62e-53	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HAPGDBDF_00955	7.78e-76	-	-	-	-	-	-	-	-
HAPGDBDF_00958	8.08e-40	-	-	-	-	-	-	-	-
HAPGDBDF_00960	2.69e-278	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPGDBDF_00965	1.58e-46	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HAPGDBDF_00967	2.72e-46	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HAPGDBDF_00975	6.14e-53	-	-	-	S	-	-	-	protein disulfide oxidoreductase activity
HAPGDBDF_00977	1.56e-70	-	-	-	-	-	-	-	-
HAPGDBDF_00978	6.09e-101	-	-	-	-	-	-	-	-
HAPGDBDF_00981	2.8e-70	-	-	-	S	-	-	-	Bacteriophage Mu Gam like protein
HAPGDBDF_00982	1.04e-76	-	-	-	-	-	-	-	-
HAPGDBDF_00983	5.52e-45	-	-	-	L	-	-	-	Domain of unknown function (DUF4373)
HAPGDBDF_00984	1.68e-191	-	-	-	S	-	-	-	IstB-like ATP binding protein
HAPGDBDF_00986	1.5e-79	-	-	-	-	-	-	-	-
HAPGDBDF_00987	1.35e-85	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HAPGDBDF_00988	1.37e-05	-	-	-	-	-	-	-	-
HAPGDBDF_00989	1.77e-50	-	-	-	S	-	-	-	DNA N-6-adenine-methyltransferase (Dam)
HAPGDBDF_00990	1.79e-22	-	-	-	S	-	-	-	YopX protein
HAPGDBDF_00997	2.87e-15	-	-	-	V	-	-	-	HNH nucleases
HAPGDBDF_00998	7.19e-73	-	-	-	S	-	-	-	Terminase small subunit
HAPGDBDF_00999	0.0	-	-	-	S	ko:K06909	-	ko00000	Phage terminase, large subunit
HAPGDBDF_01000	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HAPGDBDF_01001	5.52e-214	-	-	-	S	-	-	-	Phage Mu protein F like protein
HAPGDBDF_01002	1.17e-120	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
HAPGDBDF_01003	1.94e-248	gpG	-	-	-	-	-	-	-
HAPGDBDF_01004	1.28e-69	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HAPGDBDF_01005	6.13e-64	-	-	-	-	-	-	-	-
HAPGDBDF_01006	6.26e-119	-	-	-	-	-	-	-	-
HAPGDBDF_01007	8.36e-81	-	-	-	-	-	-	-	-
HAPGDBDF_01008	1.99e-115	-	-	-	-	-	-	-	-
HAPGDBDF_01009	1.3e-111	-	-	-	S	-	-	-	Phage tail assembly chaperone protein, TAC
HAPGDBDF_01011	0.0	-	-	-	D	-	-	-	domain protein
HAPGDBDF_01012	2.39e-200	-	-	-	S	-	-	-	Phage tail protein
HAPGDBDF_01013	8.91e-255	-	-	-	M	-	-	-	Prophage endopeptidase tail
HAPGDBDF_01015	2.57e-78	-	-	-	-	-	-	-	-
HAPGDBDF_01016	5.95e-70	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
HAPGDBDF_01020	7.84e-55	-	-	-	-	-	-	-	-
HAPGDBDF_01021	4.9e-33	-	-	-	-	-	-	-	-
HAPGDBDF_01022	7.55e-263	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HAPGDBDF_01023	2.01e-58	-	-	-	-	-	-	-	-
HAPGDBDF_01024	2.63e-55	-	-	-	S	-	-	-	Bacteriophage holin
HAPGDBDF_01025	6.85e-226	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HAPGDBDF_01027	2.96e-182	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
HAPGDBDF_01028	3.26e-88	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HAPGDBDF_01029	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HAPGDBDF_01030	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HAPGDBDF_01031	5.37e-182	-	-	-	-	-	-	-	-
HAPGDBDF_01032	1.33e-77	-	-	-	-	-	-	-	-
HAPGDBDF_01033	1.9e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HAPGDBDF_01034	2.1e-41	-	-	-	-	-	-	-	-
HAPGDBDF_01035	2.65e-245	ampC	-	-	V	-	-	-	Beta-lactamase
HAPGDBDF_01036	4.95e-250	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HAPGDBDF_01037	1.83e-175	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HAPGDBDF_01038	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
HAPGDBDF_01039	1.54e-141	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HAPGDBDF_01040	1.88e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HAPGDBDF_01041	3.44e-204	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HAPGDBDF_01042	7.28e-243	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HAPGDBDF_01043	3.04e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HAPGDBDF_01044	7.81e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HAPGDBDF_01045	1.44e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HAPGDBDF_01046	6.85e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HAPGDBDF_01047	3.66e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HAPGDBDF_01048	7.68e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HAPGDBDF_01049	5.83e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HAPGDBDF_01050	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HAPGDBDF_01051	9.14e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HAPGDBDF_01052	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HAPGDBDF_01053	5.95e-74	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HAPGDBDF_01054	2.94e-315	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HAPGDBDF_01055	1.68e-132	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HAPGDBDF_01056	1.44e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HAPGDBDF_01057	1.52e-57	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HAPGDBDF_01058	2.54e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HAPGDBDF_01059	2.15e-280	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HAPGDBDF_01060	3.2e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
HAPGDBDF_01061	2.24e-239	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HAPGDBDF_01062	2.1e-151	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HAPGDBDF_01063	3.03e-191	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HAPGDBDF_01064	3.34e-215	hicD3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HAPGDBDF_01065	3.26e-227	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HAPGDBDF_01066	7.55e-242	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HAPGDBDF_01067	3.78e-272	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HAPGDBDF_01068	0.0	glpQ3	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HAPGDBDF_01069	4.7e-207	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HAPGDBDF_01070	8.1e-261	bla2	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HAPGDBDF_01071	2.37e-107	uspA	-	-	T	-	-	-	universal stress protein
HAPGDBDF_01072	1.34e-52	-	-	-	-	-	-	-	-
HAPGDBDF_01073	7.27e-303	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HAPGDBDF_01074	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HAPGDBDF_01075	4.54e-59	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HAPGDBDF_01076	2.6e-141	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HAPGDBDF_01077	4e-105	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HAPGDBDF_01078	4.02e-145	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HAPGDBDF_01079	2.15e-137	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HAPGDBDF_01080	5.28e-105	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HAPGDBDF_01081	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HAPGDBDF_01082	2.59e-277	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HAPGDBDF_01083	7.66e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HAPGDBDF_01084	6.39e-299	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
HAPGDBDF_01085	3.56e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HAPGDBDF_01086	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HAPGDBDF_01087	5.62e-316	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HAPGDBDF_01088	1.15e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HAPGDBDF_01089	1.74e-211	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HAPGDBDF_01090	3.76e-184	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HAPGDBDF_01091	9.47e-115	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HAPGDBDF_01092	3.81e-150	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HAPGDBDF_01093	1.23e-187	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HAPGDBDF_01094	1.89e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HAPGDBDF_01095	3.17e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HAPGDBDF_01096	2.61e-199	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HAPGDBDF_01097	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HAPGDBDF_01098	5.88e-295	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HAPGDBDF_01099	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
HAPGDBDF_01100	4.71e-171	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HAPGDBDF_01101	1.92e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HAPGDBDF_01102	3.83e-295	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HAPGDBDF_01103	2.43e-264	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HAPGDBDF_01104	6.57e-291	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HAPGDBDF_01105	6.18e-197	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
HAPGDBDF_01106	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HAPGDBDF_01107	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HAPGDBDF_01108	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
HAPGDBDF_01109	1.3e-91	-	-	-	-	-	-	-	-
HAPGDBDF_01110	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HAPGDBDF_01111	2.83e-114	-	-	-	-	-	-	-	-
HAPGDBDF_01112	2.83e-138	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HAPGDBDF_01113	2.62e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HAPGDBDF_01114	5.87e-256	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HAPGDBDF_01115	9.91e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HAPGDBDF_01116	1.26e-61	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HAPGDBDF_01117	2.48e-276	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HAPGDBDF_01118	8.32e-227	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HAPGDBDF_01119	2.79e-316	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HAPGDBDF_01120	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HAPGDBDF_01121	5e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HAPGDBDF_01122	5.39e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HAPGDBDF_01123	1.31e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HAPGDBDF_01124	1.06e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HAPGDBDF_01125	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HAPGDBDF_01126	3e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HAPGDBDF_01127	1.45e-161	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HAPGDBDF_01128	5.06e-194	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HAPGDBDF_01129	8.49e-144	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HAPGDBDF_01130	4.03e-125	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HAPGDBDF_01131	7.94e-114	ykuL	-	-	S	-	-	-	(CBS) domain
HAPGDBDF_01132	2.29e-112	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HAPGDBDF_01133	6.72e-289	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HAPGDBDF_01134	1.9e-201	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HAPGDBDF_01135	1.88e-75	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HAPGDBDF_01136	1.6e-96	-	-	-	-	-	-	-	-
HAPGDBDF_01137	9.11e-106	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HAPGDBDF_01138	1.81e-274	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HAPGDBDF_01139	5.44e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HAPGDBDF_01140	7.88e-211	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HAPGDBDF_01141	2.44e-65	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
HAPGDBDF_01142	2.21e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HAPGDBDF_01143	2.06e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HAPGDBDF_01144	2.57e-224	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HAPGDBDF_01145	6.2e-242	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HAPGDBDF_01146	1.97e-72	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HAPGDBDF_01147	4.29e-108	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
HAPGDBDF_01148	3.03e-27	-	-	-	-	ko:K02671	-	ko00000,ko02035,ko02044	-
HAPGDBDF_01149	6.46e-113	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
HAPGDBDF_01151	1.56e-236	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HAPGDBDF_01152	4.7e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HAPGDBDF_01153	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HAPGDBDF_01154	1.66e-150	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HAPGDBDF_01155	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HAPGDBDF_01156	1.96e-116	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HAPGDBDF_01157	7.18e-189	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HAPGDBDF_01158	4.69e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HAPGDBDF_01159	8.38e-152	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HAPGDBDF_01160	5.16e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HAPGDBDF_01161	2e-98	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	general stress protein
HAPGDBDF_01162	1.11e-84	-	-	-	-	-	-	-	-
HAPGDBDF_01163	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HAPGDBDF_01185	1.08e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HAPGDBDF_01186	6.62e-177	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HAPGDBDF_01187	9.28e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HAPGDBDF_01188	7.12e-170	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HAPGDBDF_01189	1.85e-263	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HAPGDBDF_01190	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HAPGDBDF_01191	2.24e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
HAPGDBDF_01192	9.08e-157	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HAPGDBDF_01193	1.29e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HAPGDBDF_01194	6.31e-222	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HAPGDBDF_01195	7.21e-150	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HAPGDBDF_01196	1.6e-246	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HAPGDBDF_01197	2.68e-75	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HAPGDBDF_01198	9.52e-264	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
HAPGDBDF_01199	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HAPGDBDF_01200	1.3e-206	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HAPGDBDF_01202	3.59e-301	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HAPGDBDF_01203	2.5e-147	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HAPGDBDF_01204	1.41e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HAPGDBDF_01205	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HAPGDBDF_01206	4.1e-223	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HAPGDBDF_01207	3.22e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
HAPGDBDF_01208	7.24e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HAPGDBDF_01209	1.74e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HAPGDBDF_01210	7.01e-76	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HAPGDBDF_01211	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HAPGDBDF_01212	2.81e-231	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HAPGDBDF_01213	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HAPGDBDF_01214	5e-253	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HAPGDBDF_01215	2.34e-208	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HAPGDBDF_01216	1.44e-311	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HAPGDBDF_01217	9.39e-295	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HAPGDBDF_01218	1.56e-93	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HAPGDBDF_01219	6.45e-49	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HAPGDBDF_01220	2.06e-187	ylmH	-	-	S	-	-	-	S4 domain protein
HAPGDBDF_01221	6.52e-124	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HAPGDBDF_01222	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HAPGDBDF_01223	1.41e-241	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HAPGDBDF_01224	3.51e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HAPGDBDF_01225	7.74e-47	-	-	-	-	-	-	-	-
HAPGDBDF_01226	5.85e-158	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HAPGDBDF_01227	4.88e-276	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HAPGDBDF_01228	4.94e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HAPGDBDF_01229	3.19e-285	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HAPGDBDF_01230	9.64e-307	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HAPGDBDF_01231	4.64e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HAPGDBDF_01232	4.17e-153	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
HAPGDBDF_01233	4.97e-248	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HAPGDBDF_01234	0.0	-	-	-	N	-	-	-	domain, Protein
HAPGDBDF_01235	2.41e-157	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HAPGDBDF_01236	1.02e-155	-	-	-	S	-	-	-	repeat protein
HAPGDBDF_01237	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HAPGDBDF_01238	5.35e-220	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HAPGDBDF_01239	2.62e-168	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HAPGDBDF_01240	2.16e-39	-	-	-	-	-	-	-	-
HAPGDBDF_01241	3.45e-240	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HAPGDBDF_01242	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HAPGDBDF_01243	4.86e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HAPGDBDF_01244	6.45e-111	-	-	-	-	-	-	-	-
HAPGDBDF_01245	3.95e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HAPGDBDF_01246	4.94e-268	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HAPGDBDF_01247	8.65e-228	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HAPGDBDF_01248	2.36e-285	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HAPGDBDF_01249	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HAPGDBDF_01250	2.15e-209	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
HAPGDBDF_01251	2.64e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HAPGDBDF_01252	1.23e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HAPGDBDF_01253	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HAPGDBDF_01254	7.94e-195	-	-	-	-	-	-	-	-
HAPGDBDF_01255	9.51e-135	-	-	-	-	-	-	-	-
HAPGDBDF_01256	0.0	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
HAPGDBDF_01257	1.12e-289	-	-	-	-	-	-	-	-
HAPGDBDF_01258	7.7e-226	-	-	-	L	ko:K07482	-	ko00000	Integrase core domain
HAPGDBDF_01259	6.04e-51	-	-	-	-	-	-	-	-
HAPGDBDF_01260	2.51e-261	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HAPGDBDF_01261	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HAPGDBDF_01262	1.91e-66	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HAPGDBDF_01263	7.08e-131	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HAPGDBDF_01264	2.56e-110	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HAPGDBDF_01265	3.01e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HAPGDBDF_01266	5.47e-157	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HAPGDBDF_01267	1.01e-115	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HAPGDBDF_01268	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HAPGDBDF_01269	4.44e-84	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HAPGDBDF_01270	2.42e-239	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HAPGDBDF_01271	1.18e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HAPGDBDF_01272	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HAPGDBDF_01273	4.48e-261	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HAPGDBDF_01274	1.29e-200	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HAPGDBDF_01275	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HAPGDBDF_01276	2.4e-203	-	-	-	S	-	-	-	Tetratricopeptide repeat
HAPGDBDF_01277	4.38e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HAPGDBDF_01278	3.21e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HAPGDBDF_01279	7.8e-300	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HAPGDBDF_01280	9.6e-143	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HAPGDBDF_01281	1.3e-65	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HAPGDBDF_01282	6.47e-95	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HAPGDBDF_01283	5.12e-31	-	-	-	-	-	-	-	-
HAPGDBDF_01284	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HAPGDBDF_01285	3.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HAPGDBDF_01286	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HAPGDBDF_01287	1.22e-116	epsB	-	-	M	-	-	-	biosynthesis protein
HAPGDBDF_01288	1.09e-33	epsB	-	-	M	-	-	-	biosynthesis protein
HAPGDBDF_01289	2.02e-156	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HAPGDBDF_01290	5.54e-189	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HAPGDBDF_01291	8.71e-231	cps4D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HAPGDBDF_01292	3.31e-164	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
HAPGDBDF_01293	7.3e-86	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
HAPGDBDF_01294	8.84e-137	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
HAPGDBDF_01295	9.2e-243	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
HAPGDBDF_01296	1.91e-297	-	-	-	-	-	-	-	-
HAPGDBDF_01297	3.4e-228	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
HAPGDBDF_01298	1.19e-88	cps4J	-	-	S	-	-	-	MatE
HAPGDBDF_01299	4.34e-220	cps4J	-	-	S	-	-	-	MatE
HAPGDBDF_01300	0.0	-	3.1.4.53	-	S	ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HAPGDBDF_01301	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HAPGDBDF_01302	4.24e-218	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HAPGDBDF_01303	3.02e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HAPGDBDF_01304	1.28e-310	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HAPGDBDF_01305	6.62e-62	-	-	-	-	-	-	-	-
HAPGDBDF_01306	8.34e-228	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HAPGDBDF_01307	7.09e-180	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HAPGDBDF_01308	1.84e-67	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HAPGDBDF_01309	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HAPGDBDF_01310	1.52e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HAPGDBDF_01311	3.58e-129	-	-	-	K	-	-	-	Helix-turn-helix domain
HAPGDBDF_01312	6.75e-269	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HAPGDBDF_01313	2.84e-75	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
HAPGDBDF_01314	6.34e-178	-	-	-	Q	-	-	-	Methyltransferase
HAPGDBDF_01315	1.75e-43	-	-	-	-	-	-	-	-
HAPGDBDF_01316	8.67e-75	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPGDBDF_01322	4.16e-51	-	-	-	S	-	-	-	Membrane
HAPGDBDF_01325	2.9e-24	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HAPGDBDF_01327	6.04e-87	-	-	-	S	-	-	-	DNA binding
HAPGDBDF_01335	1.87e-24	-	-	-	-	-	-	-	-
HAPGDBDF_01338	7.13e-42	-	-	-	L	-	-	-	Conserved phage C-terminus (Phg_2220_C)
HAPGDBDF_01339	2.4e-186	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
HAPGDBDF_01341	4.83e-61	-	-	-	-	-	-	-	-
HAPGDBDF_01342	2.1e-17	-	-	-	-	-	-	-	-
HAPGDBDF_01343	2.21e-50	-	-	-	S	-	-	-	YopX protein
HAPGDBDF_01345	8.09e-235	-	-	-	-	-	-	-	-
HAPGDBDF_01348	4.83e-47	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
HAPGDBDF_01351	5.72e-117	-	-	-	L	-	-	-	HNH nucleases
HAPGDBDF_01352	1.29e-102	-	-	-	S	-	-	-	Phage terminase, small subunit
HAPGDBDF_01353	0.0	-	-	-	S	-	-	-	Phage Terminase
HAPGDBDF_01354	3.74e-32	-	-	-	S	-	-	-	Protein of unknown function (DUF1056)
HAPGDBDF_01355	8.48e-285	-	-	-	S	-	-	-	Phage portal protein
HAPGDBDF_01356	1.32e-161	-	-	-	S	-	-	-	Clp protease
HAPGDBDF_01357	9.11e-266	-	-	-	S	-	-	-	Phage capsid family
HAPGDBDF_01358	1.97e-66	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HAPGDBDF_01359	6.96e-76	-	-	-	S	-	-	-	Phage head-tail joining protein
HAPGDBDF_01360	3.74e-85	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HAPGDBDF_01361	7.47e-74	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
HAPGDBDF_01362	1.59e-135	-	-	-	S	-	-	-	Phage tail tube protein
HAPGDBDF_01363	1.58e-74	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
HAPGDBDF_01364	5.71e-33	-	-	-	-	-	-	-	-
HAPGDBDF_01365	0.0	-	-	-	D	-	-	-	domain protein
HAPGDBDF_01366	0.0	-	-	-	S	-	-	-	Phage tail protein
HAPGDBDF_01367	0.0	-	-	-	S	-	-	-	Phage minor structural protein
HAPGDBDF_01368	3.47e-186	-	-	-	-	-	-	-	-
HAPGDBDF_01371	3.51e-99	-	-	-	-	-	-	-	-
HAPGDBDF_01372	9.89e-33	-	-	-	-	-	-	-	-
HAPGDBDF_01373	2.31e-257	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HAPGDBDF_01374	1.46e-46	-	-	-	S	-	-	-	Haemolysin XhlA
HAPGDBDF_01375	3.33e-56	-	-	-	S	-	-	-	Bacteriophage holin
HAPGDBDF_01377	1.96e-293	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Cell cycle protein
HAPGDBDF_01378	3.06e-234	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAPGDBDF_01379	1.11e-90	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAPGDBDF_01380	3.82e-184	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HAPGDBDF_01381	1.89e-282	ywtF_2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HAPGDBDF_01382	2.19e-131	-	-	-	L	-	-	-	Helix-turn-helix domain
HAPGDBDF_01383	1.14e-226	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family 2
HAPGDBDF_01384	2.53e-44	-	-	-	-	-	-	-	-
HAPGDBDF_01385	1.38e-98	-	-	-	-	-	-	-	-
HAPGDBDF_01386	1.56e-276	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HAPGDBDF_01387	7.8e-123	-	-	-	-	-	-	-	-
HAPGDBDF_01388	7.22e-149	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HAPGDBDF_01389	7.68e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
HAPGDBDF_01390	3.96e-44	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HAPGDBDF_01391	8.8e-155	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HAPGDBDF_01392	2.11e-171	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HAPGDBDF_01393	5.67e-64	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HAPGDBDF_01394	1.92e-239	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HAPGDBDF_01395	2.92e-172	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
HAPGDBDF_01396	6.33e-185	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HAPGDBDF_01397	1.88e-194	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HAPGDBDF_01398	3.01e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HAPGDBDF_01399	9.83e-113	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HAPGDBDF_01400	3.17e-190	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HAPGDBDF_01401	1.13e-175	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HAPGDBDF_01402	4.64e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HAPGDBDF_01403	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HAPGDBDF_01404	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HAPGDBDF_01405	9.74e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HAPGDBDF_01406	4.46e-275	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HAPGDBDF_01407	2.95e-65	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HAPGDBDF_01408	3.28e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
HAPGDBDF_01409	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HAPGDBDF_01410	3.04e-71	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HAPGDBDF_01411	0.0	-	-	-	G	-	-	-	Major Facilitator
HAPGDBDF_01412	2.12e-274	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HAPGDBDF_01413	1.63e-121	-	-	-	-	-	-	-	-
HAPGDBDF_01414	1.24e-297	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HAPGDBDF_01415	1.47e-246	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HAPGDBDF_01416	2.41e-113	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HAPGDBDF_01417	1.8e-220	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HAPGDBDF_01418	1.53e-241	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HAPGDBDF_01419	1.19e-169	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HAPGDBDF_01420	4.42e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HAPGDBDF_01421	4.52e-111	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HAPGDBDF_01422	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HAPGDBDF_01423	2.54e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HAPGDBDF_01424	8.49e-266	pbpX2	-	-	V	-	-	-	Beta-lactamase
HAPGDBDF_01425	8.59e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HAPGDBDF_01426	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HAPGDBDF_01427	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HAPGDBDF_01428	5.75e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HAPGDBDF_01429	1.68e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HAPGDBDF_01430	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HAPGDBDF_01431	1.01e-158	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPGDBDF_01434	1.73e-67	-	-	-	-	-	-	-	-
HAPGDBDF_01435	4.78e-65	-	-	-	-	-	-	-	-
HAPGDBDF_01436	5.28e-146	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HAPGDBDF_01437	2.04e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HAPGDBDF_01438	3.13e-172	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HAPGDBDF_01439	2.56e-76	-	-	-	-	-	-	-	-
HAPGDBDF_01440	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HAPGDBDF_01441	8.2e-102	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HAPGDBDF_01442	2.43e-150	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
HAPGDBDF_01443	2.97e-210	-	-	-	G	-	-	-	Fructosamine kinase
HAPGDBDF_01444	4.01e-200	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
HAPGDBDF_01445	2.47e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HAPGDBDF_01446	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HAPGDBDF_01447	2.61e-132	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HAPGDBDF_01448	4.35e-204	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HAPGDBDF_01449	1.84e-284	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HAPGDBDF_01450	1.42e-217	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HAPGDBDF_01451	3.5e-164	-	-	-	C	-	-	-	Enoyl-(Acyl carrier protein) reductase
HAPGDBDF_01452	2.32e-194	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HAPGDBDF_01453	1.09e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HAPGDBDF_01454	9.21e-94	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HAPGDBDF_01455	4.81e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HAPGDBDF_01456	7.7e-110	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HAPGDBDF_01457	1.15e-94	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HAPGDBDF_01458	7.92e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HAPGDBDF_01459	2.84e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HAPGDBDF_01460	8.64e-224	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HAPGDBDF_01461	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HAPGDBDF_01462	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HAPGDBDF_01463	1.74e-251	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HAPGDBDF_01464	1.18e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HAPGDBDF_01465	4.94e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HAPGDBDF_01466	4.14e-190	-	-	-	-	-	-	-	-
HAPGDBDF_01467	6.08e-253	-	-	-	-	-	-	-	-
HAPGDBDF_01468	2.02e-168	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HAPGDBDF_01469	6.19e-208	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HAPGDBDF_01470	0.000138	yjdF	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HAPGDBDF_01471	1.28e-148	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGDBDF_01472	5.53e-94	-	-	-	K	-	-	-	MarR family
HAPGDBDF_01473	6.64e-109	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HAPGDBDF_01475	4.17e-204	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HAPGDBDF_01476	1.27e-174	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HAPGDBDF_01477	5.11e-266	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HAPGDBDF_01478	1.51e-132	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
HAPGDBDF_01479	0.0	nox4	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HAPGDBDF_01481	3.78e-221	cryZ	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HAPGDBDF_01482	5.72e-207	-	-	-	K	-	-	-	Transcriptional regulator
HAPGDBDF_01483	7.09e-101	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
HAPGDBDF_01484	1.39e-143	-	-	-	GM	-	-	-	NmrA-like family
HAPGDBDF_01485	8.81e-205	-	-	-	S	-	-	-	Alpha beta hydrolase
HAPGDBDF_01486	2.49e-167	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HAPGDBDF_01487	4.85e-61	thgA3	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HAPGDBDF_01488	1.2e-200	is18	-	-	L	-	-	-	Integrase core domain
HAPGDBDF_01489	2.48e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
HAPGDBDF_01490	1.46e-70	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HAPGDBDF_01491	1.06e-69	-	-	-	P	-	-	-	Rhodanese Homology Domain
HAPGDBDF_01492	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HAPGDBDF_01493	2.74e-112	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HAPGDBDF_01494	2.08e-213	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HAPGDBDF_01495	5.09e-165	drrB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HAPGDBDF_01496	1.75e-295	-	-	-	M	-	-	-	O-Antigen ligase
HAPGDBDF_01497	6.85e-164	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HAPGDBDF_01498	1.09e-249	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HAPGDBDF_01499	3.17e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HAPGDBDF_01500	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HAPGDBDF_01502	7.03e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HAPGDBDF_01503	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HAPGDBDF_01504	8.69e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HAPGDBDF_01505	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HAPGDBDF_01506	2.51e-98	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
HAPGDBDF_01507	7.94e-218	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HAPGDBDF_01508	3.13e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HAPGDBDF_01509	3.99e-92	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HAPGDBDF_01510	7.1e-176	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HAPGDBDF_01511	1.3e-132	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HAPGDBDF_01512	2.69e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HAPGDBDF_01513	2.24e-126	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HAPGDBDF_01514	1.72e-245	-	-	-	S	-	-	-	Helix-turn-helix domain
HAPGDBDF_01515	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HAPGDBDF_01516	1.25e-39	-	-	-	M	-	-	-	Lysin motif
HAPGDBDF_01517	1.27e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HAPGDBDF_01518	1.98e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HAPGDBDF_01519	4.84e-313	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HAPGDBDF_01520	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HAPGDBDF_01521	7.1e-292	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HAPGDBDF_01522	7.48e-192	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HAPGDBDF_01523	1.39e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HAPGDBDF_01524	1.27e-291	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HAPGDBDF_01525	6.46e-109	-	-	-	-	-	-	-	-
HAPGDBDF_01526	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HAPGDBDF_01527	4.04e-242	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HAPGDBDF_01528	1.8e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HAPGDBDF_01529	2.03e-189	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HAPGDBDF_01530	5.66e-207	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HAPGDBDF_01531	3.29e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HAPGDBDF_01532	9.33e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HAPGDBDF_01533	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HAPGDBDF_01534	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HAPGDBDF_01535	1.43e-251	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HAPGDBDF_01536	4.12e-159	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HAPGDBDF_01537	1.27e-222	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
HAPGDBDF_01538	7.05e-219	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
HAPGDBDF_01539	5.13e-292	XK27_05470	-	-	E	-	-	-	Methionine synthase
HAPGDBDF_01541	2.25e-207	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HAPGDBDF_01542	1.01e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HAPGDBDF_01543	8.11e-203	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HAPGDBDF_01544	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HAPGDBDF_01545	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HAPGDBDF_01546	1.5e-227	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HAPGDBDF_01547	6.84e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HAPGDBDF_01548	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HAPGDBDF_01549	1.27e-217	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HAPGDBDF_01550	2.4e-137	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HAPGDBDF_01551	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HAPGDBDF_01552	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HAPGDBDF_01553	5.43e-228	-	-	-	K	-	-	-	Transcriptional regulator
HAPGDBDF_01554	3.21e-215	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HAPGDBDF_01555	3.8e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HAPGDBDF_01556	9.17e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HAPGDBDF_01557	1.07e-43	-	-	-	S	-	-	-	YozE SAM-like fold
HAPGDBDF_01558	4.19e-203	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HAPGDBDF_01559	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HAPGDBDF_01560	1.18e-310	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HAPGDBDF_01561	3.22e-87	-	-	-	-	-	-	-	-
HAPGDBDF_01562	0.0	gshR1	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HAPGDBDF_01563	1.48e-98	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HAPGDBDF_01564	3.29e-121	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HAPGDBDF_01565	0.0	tarL	2.7.8.14, 2.7.8.47	-	H	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HAPGDBDF_01566	2.89e-273	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	H	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HAPGDBDF_01567	1.17e-181	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HAPGDBDF_01568	8.6e-31	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HAPGDBDF_01569	2.13e-151	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HAPGDBDF_01570	8.23e-291	-	-	-	-	-	-	-	-
HAPGDBDF_01571	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HAPGDBDF_01572	7.79e-78	-	-	-	-	-	-	-	-
HAPGDBDF_01573	2.79e-181	-	-	-	-	-	-	-	-
HAPGDBDF_01574	7.45e-313	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HAPGDBDF_01575	1.05e-176	XK27_00890	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
HAPGDBDF_01576	9.3e-167	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
HAPGDBDF_01577	1.33e-67	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
HAPGDBDF_01579	6e-268	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
HAPGDBDF_01580	4.87e-191	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HAPGDBDF_01581	2.37e-65	-	-	-	-	-	-	-	-
HAPGDBDF_01582	2.29e-36	-	-	-	-	-	-	-	-
HAPGDBDF_01583	1.96e-168	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HAPGDBDF_01584	2.47e-101	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
HAPGDBDF_01585	1.11e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
HAPGDBDF_01586	1.97e-87	-	-	-	K	-	-	-	Transcriptional regulator
HAPGDBDF_01587	8.39e-234	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HAPGDBDF_01588	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HAPGDBDF_01589	9.28e-171	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HAPGDBDF_01590	4.87e-205	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HAPGDBDF_01591	1.27e-115	-	-	-	F	-	-	-	NUDIX domain
HAPGDBDF_01592	3.42e-176	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
HAPGDBDF_01593	2.08e-92	-	-	-	S	-	-	-	LuxR family transcriptional regulator
HAPGDBDF_01594	2.24e-167	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
HAPGDBDF_01596	7.75e-93	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HAPGDBDF_01597	2.01e-145	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HAPGDBDF_01598	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HAPGDBDF_01599	1.71e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HAPGDBDF_01600	1.9e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HAPGDBDF_01601	9.72e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HAPGDBDF_01602	1.65e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HAPGDBDF_01603	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HAPGDBDF_01604	5.04e-82	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HAPGDBDF_01605	3.28e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HAPGDBDF_01606	8.53e-268	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
HAPGDBDF_01607	3.03e-186	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
HAPGDBDF_01608	6.79e-249	-	-	-	-	-	-	-	-
HAPGDBDF_01609	1.9e-156	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HAPGDBDF_01610	4.35e-159	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HAPGDBDF_01611	1.38e-232	-	-	-	V	-	-	-	LD-carboxypeptidase
HAPGDBDF_01612	1.23e-311	-	-	-	M	ko:K07273	-	ko00000	hydrolase, family 25
HAPGDBDF_01613	6.74e-101	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HAPGDBDF_01614	3.46e-267	mccF	-	-	V	-	-	-	LD-carboxypeptidase
HAPGDBDF_01615	9.63e-307	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HAPGDBDF_01616	9.19e-95	-	-	-	S	-	-	-	SnoaL-like domain
HAPGDBDF_01617	4.17e-186	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HAPGDBDF_01618	1.55e-309	-	-	-	P	-	-	-	Major Facilitator Superfamily
HAPGDBDF_01619	1.26e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HAPGDBDF_01620	1.44e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HAPGDBDF_01622	9.98e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HAPGDBDF_01623	2.12e-142	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HAPGDBDF_01624	3.6e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HAPGDBDF_01625	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HAPGDBDF_01626	8.03e-229	phnT	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HAPGDBDF_01627	8.06e-234	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HAPGDBDF_01628	0.0	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAPGDBDF_01629	5.32e-109	-	-	-	T	-	-	-	Universal stress protein family
HAPGDBDF_01630	1.58e-203	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HAPGDBDF_01631	2.45e-142	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HAPGDBDF_01632	1.34e-237	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HAPGDBDF_01634	3.25e-165	dnaD	-	-	L	ko:K02086	-	ko00000	Replication initiation and membrane attachment
HAPGDBDF_01635	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HAPGDBDF_01636	3.1e-289	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HAPGDBDF_01637	2.53e-107	ypmB	-	-	S	-	-	-	protein conserved in bacteria
HAPGDBDF_01638	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HAPGDBDF_01639	1.48e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HAPGDBDF_01640	1.1e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HAPGDBDF_01641	1.77e-262	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HAPGDBDF_01642	8.61e-251	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HAPGDBDF_01643	3.36e-247	galM2	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HAPGDBDF_01644	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HAPGDBDF_01645	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HAPGDBDF_01646	1.38e-156	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HAPGDBDF_01647	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HAPGDBDF_01648	3.86e-192	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HAPGDBDF_01649	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HAPGDBDF_01650	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HAPGDBDF_01651	3.23e-58	-	-	-	-	-	-	-	-
HAPGDBDF_01652	1.25e-66	-	-	-	-	-	-	-	-
HAPGDBDF_01653	5.03e-182	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
HAPGDBDF_01654	1.48e-218	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HAPGDBDF_01655	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HAPGDBDF_01656	8.39e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HAPGDBDF_01657	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HAPGDBDF_01658	1.06e-53	-	-	-	-	-	-	-	-
HAPGDBDF_01659	4e-40	-	-	-	S	-	-	-	CsbD-like
HAPGDBDF_01660	2.22e-55	-	-	-	S	-	-	-	transglycosylase associated protein
HAPGDBDF_01661	5.79e-21	-	-	-	-	-	-	-	-
HAPGDBDF_01662	1.51e-48	-	-	-	-	-	-	-	-
HAPGDBDF_01663	3.13e-99	-	-	-	L	-	-	-	Transposase DDE domain
HAPGDBDF_01664	7.87e-88	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HAPGDBDF_01665	3.6e-211	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HAPGDBDF_01666	5.58e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HAPGDBDF_01667	5.28e-100	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HAPGDBDF_01668	6.05e-108	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
HAPGDBDF_01669	2.05e-55	-	-	-	-	-	-	-	-
HAPGDBDF_01670	5.93e-60	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HAPGDBDF_01671	9.96e-147	-	1.14.99.53	AA10	S	ko:K21713	-	ko00000,ko01000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
HAPGDBDF_01672	1.05e-41	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HAPGDBDF_01673	1.33e-273	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HAPGDBDF_01674	8.23e-39	-	-	-	-	-	-	-	-
HAPGDBDF_01675	1.48e-71	-	-	-	-	-	-	-	-
HAPGDBDF_01676	1.14e-193	-	-	-	O	-	-	-	Band 7 protein
HAPGDBDF_01677	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HAPGDBDF_01678	6.05e-121	-	-	-	K	-	-	-	transcriptional regulator
HAPGDBDF_01679	4.4e-246	rsgA_2	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HAPGDBDF_01680	2.01e-113	ykhA	-	-	I	-	-	-	Thioesterase superfamily
HAPGDBDF_01681	7.52e-207	-	-	-	K	-	-	-	LysR substrate binding domain
HAPGDBDF_01682	1.48e-161	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HAPGDBDF_01683	5.01e-129	-	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
HAPGDBDF_01684	2.29e-175	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HAPGDBDF_01685	4.82e-179	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HAPGDBDF_01686	6.43e-203	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HAPGDBDF_01687	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HAPGDBDF_01688	1.71e-91	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HAPGDBDF_01689	2.14e-95	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HAPGDBDF_01690	7.64e-290	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HAPGDBDF_01691	1.26e-162	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HAPGDBDF_01692	3.47e-215	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HAPGDBDF_01693	6.16e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HAPGDBDF_01694	1.62e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HAPGDBDF_01695	8.55e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HAPGDBDF_01696	3.27e-229	yneE	-	-	K	-	-	-	Transcriptional regulator
HAPGDBDF_01697	4.61e-163	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HAPGDBDF_01698	6.67e-12	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HAPGDBDF_01700	1.49e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HAPGDBDF_01701	2.69e-252	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HAPGDBDF_01702	7.96e-273	hipO1	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	Peptidase family M20/M25/M40
HAPGDBDF_01703	1.62e-276	-	-	-	E	-	-	-	glutamate:sodium symporter activity
HAPGDBDF_01704	1.95e-88	ybbJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HAPGDBDF_01705	2.04e-226	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
HAPGDBDF_01706	5.89e-126	entB	-	-	Q	-	-	-	Isochorismatase family
HAPGDBDF_01707	4.82e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HAPGDBDF_01708	6.25e-288	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HAPGDBDF_01709	1.57e-142	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HAPGDBDF_01710	1.2e-165	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HAPGDBDF_01711	6.03e-226	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HAPGDBDF_01712	3.3e-86	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
HAPGDBDF_01713	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
HAPGDBDF_01715	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HAPGDBDF_01716	2.05e-179	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HAPGDBDF_01717	9.06e-112	-	-	-	-	-	-	-	-
HAPGDBDF_01718	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HAPGDBDF_01719	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HAPGDBDF_01720	3.2e-70	-	-	-	-	-	-	-	-
HAPGDBDF_01721	3.15e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HAPGDBDF_01722	1.57e-179	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HAPGDBDF_01723	6.42e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HAPGDBDF_01724	9.99e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HAPGDBDF_01725	1.6e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HAPGDBDF_01726	7.69e-300	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HAPGDBDF_01727	1.46e-77	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HAPGDBDF_01728	2.85e-293	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HAPGDBDF_01729	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HAPGDBDF_01730	4.49e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HAPGDBDF_01731	3.33e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HAPGDBDF_01732	2.17e-244	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HAPGDBDF_01733	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HAPGDBDF_01734	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HAPGDBDF_01735	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HAPGDBDF_01736	1.61e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HAPGDBDF_01737	1.84e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HAPGDBDF_01738	3.16e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HAPGDBDF_01739	1.21e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HAPGDBDF_01740	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HAPGDBDF_01741	1.62e-173	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HAPGDBDF_01742	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HAPGDBDF_01743	1.01e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HAPGDBDF_01744	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HAPGDBDF_01745	5.04e-278	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HAPGDBDF_01746	3.93e-41	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HAPGDBDF_01747	2.83e-144	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HAPGDBDF_01748	8.28e-73	-	-	-	-	-	-	-	-
HAPGDBDF_01749	1.36e-136	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAPGDBDF_01750	2.2e-223	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HAPGDBDF_01751	7.11e-135	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HAPGDBDF_01752	4.51e-284	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HAPGDBDF_01753	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HAPGDBDF_01754	5.28e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HAPGDBDF_01755	4.49e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HAPGDBDF_01756	7.16e-201	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HAPGDBDF_01757	7.55e-44	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HAPGDBDF_01758	2.81e-313	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HAPGDBDF_01759	4.82e-194	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HAPGDBDF_01760	2.82e-91	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HAPGDBDF_01761	1.7e-96	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HAPGDBDF_01762	1.43e-129	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HAPGDBDF_01763	3.49e-248	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HAPGDBDF_01764	2.33e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HAPGDBDF_01765	7.97e-71	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HAPGDBDF_01766	1.55e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HAPGDBDF_01767	8.15e-125	-	-	-	K	-	-	-	Transcriptional regulator
HAPGDBDF_01768	9.81e-27	-	-	-	-	-	-	-	-
HAPGDBDF_01771	2.97e-41	-	-	-	-	-	-	-	-
HAPGDBDF_01772	3.11e-73	-	-	-	-	-	-	-	-
HAPGDBDF_01773	8.37e-126	-	-	-	S	-	-	-	Protein conserved in bacteria
HAPGDBDF_01774	1.34e-232	-	-	-	-	-	-	-	-
HAPGDBDF_01775	1.77e-205	-	-	-	-	-	-	-	-
HAPGDBDF_01776	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HAPGDBDF_01777	7.79e-85	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
HAPGDBDF_01778	3.8e-224	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HAPGDBDF_01779	7.77e-179	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HAPGDBDF_01780	1.44e-31	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HAPGDBDF_01781	1.15e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HAPGDBDF_01782	1.62e-141	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HAPGDBDF_01783	2.6e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HAPGDBDF_01784	6.33e-46	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HAPGDBDF_01785	3.52e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HAPGDBDF_01786	9.29e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HAPGDBDF_01787	5.33e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HAPGDBDF_01788	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HAPGDBDF_01789	0.0	-	-	-	S	-	-	-	membrane
HAPGDBDF_01790	2.5e-71	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HAPGDBDF_01791	2.33e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
HAPGDBDF_01792	3.78e-143	-	-	-	S	-	-	-	membrane
HAPGDBDF_01793	1.09e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HAPGDBDF_01794	7.5e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HAPGDBDF_01795	6.11e-249	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HAPGDBDF_01796	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HAPGDBDF_01797	6.88e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HAPGDBDF_01798	4.45e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HAPGDBDF_01799	1.72e-120	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HAPGDBDF_01800	3.67e-178	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HAPGDBDF_01801	1.37e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HAPGDBDF_01802	1.4e-208	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HAPGDBDF_01803	1.77e-122	-	-	-	S	-	-	-	SdpI/YhfL protein family
HAPGDBDF_01804	9.59e-289	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HAPGDBDF_01805	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HAPGDBDF_01806	1.93e-218	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HAPGDBDF_01807	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HAPGDBDF_01808	1.38e-155	csrR	-	-	K	-	-	-	response regulator
HAPGDBDF_01809	3.12e-311	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HAPGDBDF_01810	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HAPGDBDF_01811	1.09e-223	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HAPGDBDF_01812	3.06e-124	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HAPGDBDF_01813	3.66e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HAPGDBDF_01814	3.04e-280	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HAPGDBDF_01815	3.85e-179	yqeM	-	-	Q	-	-	-	Methyltransferase
HAPGDBDF_01816	1.06e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HAPGDBDF_01817	1.71e-149	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HAPGDBDF_01818	4.19e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HAPGDBDF_01819	2.19e-67	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HAPGDBDF_01820	3.81e-276	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HAPGDBDF_01821	1.34e-125	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HAPGDBDF_01822	8.99e-114	-	-	-	-	-	-	-	-
HAPGDBDF_01823	9.51e-317	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HAPGDBDF_01824	4.83e-175	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HAPGDBDF_01825	1.64e-83	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HAPGDBDF_01826	1.18e-250	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HAPGDBDF_01827	7.03e-307	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
HAPGDBDF_01828	4.59e-73	-	-	-	-	-	-	-	-
HAPGDBDF_01829	6.88e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HAPGDBDF_01830	6.92e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HAPGDBDF_01831	2.37e-109	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HAPGDBDF_01832	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HAPGDBDF_01833	3.5e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HAPGDBDF_01834	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HAPGDBDF_01835	1.58e-117	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HAPGDBDF_01836	1.92e-133	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HAPGDBDF_01837	3.19e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HAPGDBDF_01838	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HAPGDBDF_01839	8.51e-155	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HAPGDBDF_01840	1.04e-141	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HAPGDBDF_01841	4.07e-60	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HAPGDBDF_01842	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HAPGDBDF_01843	2.71e-108	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HAPGDBDF_01844	3.17e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HAPGDBDF_01845	5.21e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HAPGDBDF_01846	1.82e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HAPGDBDF_01847	2.87e-47	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
HAPGDBDF_01848	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HAPGDBDF_01849	3.04e-29	-	-	-	S	-	-	-	Virus attachment protein p12 family
HAPGDBDF_01850	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HAPGDBDF_01851	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HAPGDBDF_01852	1.29e-148	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HAPGDBDF_01853	2.94e-71	ytzB	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HAPGDBDF_01854	2.8e-155	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HAPGDBDF_01855	7.24e-197	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
HAPGDBDF_01856	8.17e-285	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HAPGDBDF_01857	6.35e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HAPGDBDF_01858	3.6e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HAPGDBDF_01859	4.06e-65	-	-	-	-	-	-	-	-
HAPGDBDF_01860	1.09e-196	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HAPGDBDF_01861	1.78e-153	draG	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HAPGDBDF_01862	5.76e-135	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HAPGDBDF_01863	2.82e-138	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HAPGDBDF_01864	9.64e-248	-	-	-	S	-	-	-	Fn3-like domain
HAPGDBDF_01865	1.65e-80	-	-	-	-	-	-	-	-
HAPGDBDF_01866	0.0	-	-	-	-	-	-	-	-
HAPGDBDF_01867	5.19e-309	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HAPGDBDF_01868	3.73e-107	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAPGDBDF_01870	3.3e-151	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HAPGDBDF_01871	1.96e-137	-	-	-	-	-	-	-	-
HAPGDBDF_01872	5.21e-137	-	-	-	S	ko:K09962	-	ko00000	Nucleotidyltransferase
HAPGDBDF_01873	1.23e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HAPGDBDF_01874	4.9e-283	ribA	3.5.4.25, 4.1.99.12	-	H	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HAPGDBDF_01875	8.71e-111	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HAPGDBDF_01876	4.26e-218	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HAPGDBDF_01877	1.7e-112	-	-	-	S	-	-	-	membrane
HAPGDBDF_01878	3.13e-99	-	-	-	L	-	-	-	Transposase DDE domain
HAPGDBDF_01879	3.33e-89	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HAPGDBDF_01880	0.0	-	-	-	S	-	-	-	membrane
HAPGDBDF_01881	4.29e-26	-	-	-	S	-	-	-	NUDIX domain
HAPGDBDF_01882	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HAPGDBDF_01883	1.15e-235	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
HAPGDBDF_01884	1.17e-100	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
HAPGDBDF_01885	4.43e-129	-	-	-	-	-	-	-	-
HAPGDBDF_01886	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HAPGDBDF_01887	9.9e-144	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HAPGDBDF_01888	6.59e-227	-	-	-	K	-	-	-	LysR substrate binding domain
HAPGDBDF_01889	2.41e-233	-	-	-	M	-	-	-	Peptidase family S41
HAPGDBDF_01890	4.28e-272	-	-	-	-	-	-	-	-
HAPGDBDF_01891	1.03e-240	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HAPGDBDF_01892	0.0	yhaN	-	-	L	-	-	-	AAA domain
HAPGDBDF_01893	4.47e-296	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HAPGDBDF_01894	9.94e-71	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HAPGDBDF_01895	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HAPGDBDF_01896	2.43e-18	-	-	-	-	-	-	-	-
HAPGDBDF_01897	2.07e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HAPGDBDF_01898	5.58e-271	arcT	-	-	E	-	-	-	Aminotransferase
HAPGDBDF_01899	8.08e-133	argO	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
HAPGDBDF_01900	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	Alanine-glyoxylate amino-transferase
HAPGDBDF_01901	1.65e-46	dltC2	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HAPGDBDF_01902	1.72e-148	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HAPGDBDF_01903	7.06e-271	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
HAPGDBDF_01904	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HAPGDBDF_01905	1.02e-285	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HAPGDBDF_01906	4.9e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HAPGDBDF_01907	2.37e-68	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HAPGDBDF_01908	1.34e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HAPGDBDF_01909	0.0	celR	-	-	K	-	-	-	PRD domain
HAPGDBDF_01910	6.25e-138	-	-	-	-	-	-	-	-
HAPGDBDF_01911	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HAPGDBDF_01912	4.64e-106	-	-	-	-	-	-	-	-
HAPGDBDF_01913	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HAPGDBDF_01914	8.2e-102	yybD	-	-	S	ko:K02348	-	ko00000	Acetyltransferase (GNAT) domain
HAPGDBDF_01917	1.79e-42	-	-	-	-	-	-	-	-
HAPGDBDF_01918	2.69e-316	dinF	-	-	V	-	-	-	MatE
HAPGDBDF_01919	3.13e-99	-	-	-	L	-	-	-	Transposase DDE domain
HAPGDBDF_01920	3.33e-89	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HAPGDBDF_01921	0.0	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HAPGDBDF_01922	0.0	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
HAPGDBDF_01923	2.54e-225	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
HAPGDBDF_01924	3.72e-145	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HAPGDBDF_01925	7.32e-292	sat	2.7.7.4	-	H	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HAPGDBDF_01926	0.0	-	-	-	S	-	-	-	Protein conserved in bacteria
HAPGDBDF_01927	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HAPGDBDF_01928	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HAPGDBDF_01929	8.01e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
HAPGDBDF_01930	4.91e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
HAPGDBDF_01931	1.12e-236	-	-	-	-	-	-	-	-
HAPGDBDF_01932	9.03e-16	-	-	-	-	-	-	-	-
HAPGDBDF_01933	4.29e-87	-	-	-	-	-	-	-	-
HAPGDBDF_01936	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
HAPGDBDF_01937	7.12e-62	-	-	-	-	-	-	-	-
HAPGDBDF_01938	8.82e-119	-	-	-	-	-	-	-	-
HAPGDBDF_01939	2.2e-111	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HAPGDBDF_01940	3.54e-145	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HAPGDBDF_01941	4.56e-78	-	-	-	-	-	-	-	-
HAPGDBDF_01942	5.37e-74	-	-	-	-	-	-	-	-
HAPGDBDF_01943	9.01e-179	agrA	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HAPGDBDF_01944	8.83e-285	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HAPGDBDF_01945	7.83e-140	-	-	-	-	-	-	-	-
HAPGDBDF_01946	1.14e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HAPGDBDF_01947	9.36e-205	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HAPGDBDF_01948	1.64e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
HAPGDBDF_01949	5.2e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HAPGDBDF_01950	6.96e-198	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HAPGDBDF_01952	2.57e-226	-	-	-	K	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
HAPGDBDF_01953	3.06e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HAPGDBDF_01954	3.03e-135	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HAPGDBDF_01956	1.48e-315	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
HAPGDBDF_01957	3.55e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HAPGDBDF_01958	2.07e-155	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HAPGDBDF_01959	5.45e-162	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HAPGDBDF_01960	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HAPGDBDF_01961	6.16e-193	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HAPGDBDF_01962	3.93e-222	ugpA	-	-	U	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAPGDBDF_01963	1.45e-258	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
HAPGDBDF_01964	9.54e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HAPGDBDF_01965	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HAPGDBDF_01966	3.03e-193	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HAPGDBDF_01967	5.04e-176	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HAPGDBDF_01968	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HAPGDBDF_01969	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HAPGDBDF_01970	2.95e-160	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HAPGDBDF_01971	3.03e-122	mraW1	-	-	J	-	-	-	Putative rRNA methylase
HAPGDBDF_01972	9.32e-40	-	-	-	-	-	-	-	-
HAPGDBDF_01973	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HAPGDBDF_01974	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HAPGDBDF_01975	0.0	-	-	-	S	-	-	-	Pfam Methyltransferase
HAPGDBDF_01976	4.75e-298	-	-	-	N	-	-	-	Cell shape-determining protein MreB
HAPGDBDF_01977	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
HAPGDBDF_01978	2.78e-273	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HAPGDBDF_01979	6.75e-157	-	-	-	-	-	-	-	-
HAPGDBDF_01980	1.94e-149	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HAPGDBDF_01981	4.94e-197	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HAPGDBDF_01982	1.07e-213	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HAPGDBDF_01983	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HAPGDBDF_01984	2.42e-238	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HAPGDBDF_01985	1.33e-292	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HAPGDBDF_01986	5.42e-142	-	-	-	GK	-	-	-	ROK family
HAPGDBDF_01987	9.04e-155	-	-	-	P	-	-	-	Major Facilitator Superfamily
HAPGDBDF_01988	5.22e-19	-	-	-	P	-	-	-	Major Facilitator Superfamily
HAPGDBDF_01989	7e-208	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HAPGDBDF_01990	2.22e-169	-	-	-	L	-	-	-	Helix-turn-helix domain
HAPGDBDF_01991	1.98e-184	lipA	-	-	I	-	-	-	Carboxylesterase family
HAPGDBDF_01992	1.24e-144	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HAPGDBDF_01993	1.78e-201	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HAPGDBDF_01994	1.58e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HAPGDBDF_01995	2.07e-123	-	-	-	-	-	-	-	-
HAPGDBDF_01996	1.5e-235	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
HAPGDBDF_01997	5.4e-118	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
HAPGDBDF_02009	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HAPGDBDF_02012	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HAPGDBDF_02013	1.56e-46	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HAPGDBDF_02014	5.8e-291	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HAPGDBDF_02015	3.79e-291	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HAPGDBDF_02016	2.16e-241	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HAPGDBDF_02017	2.04e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HAPGDBDF_02018	1.41e-285	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HAPGDBDF_02019	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HAPGDBDF_02020	1.24e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HAPGDBDF_02021	5.6e-41	-	-	-	-	-	-	-	-
HAPGDBDF_02022	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HAPGDBDF_02023	2.5e-132	-	-	-	L	-	-	-	Integrase
HAPGDBDF_02024	3.4e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HAPGDBDF_02025	5.67e-231	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HAPGDBDF_02026	2.81e-257	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HAPGDBDF_02027	3.59e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HAPGDBDF_02028	3.44e-210	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HAPGDBDF_02029	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HAPGDBDF_02030	3.85e-76	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
HAPGDBDF_02031	4.78e-171	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HAPGDBDF_02032	1.36e-208	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HAPGDBDF_02033	3.51e-251	-	-	-	M	-	-	-	MucBP domain
HAPGDBDF_02034	0.0	-	-	-	-	-	-	-	-
HAPGDBDF_02035	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HAPGDBDF_02036	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HAPGDBDF_02037	4.77e-216	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HAPGDBDF_02038	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HAPGDBDF_02039	7.89e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HAPGDBDF_02040	3.5e-93	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HAPGDBDF_02041	1.13e-257	yueF	-	-	S	-	-	-	AI-2E family transporter
HAPGDBDF_02042	4.22e-215	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HAPGDBDF_02043	7.17e-39	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HAPGDBDF_02044	8.01e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
HAPGDBDF_02045	5.34e-168	lytE	-	-	M	-	-	-	NlpC/P60 family
HAPGDBDF_02046	6.62e-138	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HAPGDBDF_02047	3.93e-180	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HAPGDBDF_02048	1.39e-169	-	-	-	-	-	-	-	-
HAPGDBDF_02049	3.82e-128	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HAPGDBDF_02050	5.7e-36	-	-	-	-	-	-	-	-
HAPGDBDF_02051	1.17e-42	-	-	-	-	-	-	-	-
HAPGDBDF_02052	2.54e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HAPGDBDF_02053	2.59e-69	-	-	-	-	-	-	-	-
HAPGDBDF_02054	4.83e-151	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
HAPGDBDF_02055	1.71e-304	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HAPGDBDF_02056	2.94e-190	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HAPGDBDF_02057	5.67e-257	cps3I	-	-	G	-	-	-	Acyltransferase family
HAPGDBDF_02058	1.75e-256	cps3H	-	-	-	-	-	-	-
HAPGDBDF_02059	2.03e-208	cps3F	-	-	-	-	-	-	-
HAPGDBDF_02060	3.98e-143	cps3E	-	-	-	-	-	-	-
HAPGDBDF_02061	5.58e-260	cps3D	-	-	-	-	-	-	-
HAPGDBDF_02062	6.91e-283	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HAPGDBDF_02063	7.72e-228	cps3B	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HAPGDBDF_02064	4.93e-170	cps3A	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HAPGDBDF_02066	6.17e-71	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
HAPGDBDF_02067	7.22e-283	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HAPGDBDF_02069	3.69e-277	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HAPGDBDF_02070	3.98e-169	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HAPGDBDF_02071	1.23e-200	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HAPGDBDF_02072	4.75e-267	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HAPGDBDF_02073	4.4e-273	pbpX	-	-	V	-	-	-	Beta-lactamase
HAPGDBDF_02074	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HAPGDBDF_02075	2.22e-169	-	-	-	L	-	-	-	Helix-turn-helix domain
HAPGDBDF_02076	7e-208	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HAPGDBDF_02077	2.9e-139	-	-	-	-	-	-	-	-
HAPGDBDF_02078	7.62e-97	-	-	-	-	-	-	-	-
HAPGDBDF_02080	1.93e-210	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HAPGDBDF_02081	5.45e-314	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HAPGDBDF_02082	3.93e-99	-	-	-	T	-	-	-	Universal stress protein family
HAPGDBDF_02084	5.62e-316	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HAPGDBDF_02085	1.94e-245	mocA	-	-	S	-	-	-	Oxidoreductase
HAPGDBDF_02086	6.22e-43	cspP	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HAPGDBDF_02087	7.34e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HAPGDBDF_02088	1.67e-177	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HAPGDBDF_02089	9.33e-195	gntR	-	-	K	-	-	-	rpiR family
HAPGDBDF_02090	1.94e-213	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HAPGDBDF_02091	2.75e-304	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HAPGDBDF_02092	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HAPGDBDF_02093	5.56e-130	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAPGDBDF_02094	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HAPGDBDF_02095	1.59e-242	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HAPGDBDF_02096	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HAPGDBDF_02097	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HAPGDBDF_02098	5.11e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HAPGDBDF_02099	3.86e-262	camS	-	-	S	-	-	-	sex pheromone
HAPGDBDF_02100	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HAPGDBDF_02101	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HAPGDBDF_02102	1.39e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HAPGDBDF_02103	1.13e-120	yebE	-	-	S	-	-	-	UPF0316 protein
HAPGDBDF_02104	8.19e-134	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HAPGDBDF_02105	3.41e-146	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HAPGDBDF_02106	3.86e-235	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HAPGDBDF_02107	4.92e-212	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HAPGDBDF_02108	6.91e-234	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HAPGDBDF_02109	1.24e-66	-	-	-	S	-	-	-	protein conserved in bacteria
HAPGDBDF_02110	1.02e-121	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HAPGDBDF_02111	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HAPGDBDF_02112	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HAPGDBDF_02113	7.76e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HAPGDBDF_02114	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HAPGDBDF_02115	0.0	-	-	-	S	ko:K06889	-	ko00000	Alpha beta
HAPGDBDF_02116	6.07e-33	-	-	-	-	-	-	-	-
HAPGDBDF_02117	4.37e-128	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HAPGDBDF_02118	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HAPGDBDF_02119	2.6e-212	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
HAPGDBDF_02120	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HAPGDBDF_02121	6.5e-215	mleR	-	-	K	-	-	-	LysR family
HAPGDBDF_02122	3.06e-205	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
HAPGDBDF_02123	1.98e-122	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HAPGDBDF_02124	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HAPGDBDF_02125	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HAPGDBDF_02126	2.05e-231	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HAPGDBDF_02127	1.38e-19	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HAPGDBDF_02132	9.54e-65	-	-	-	K	-	-	-	sequence-specific DNA binding
HAPGDBDF_02133	2.06e-234	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HAPGDBDF_02134	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
HAPGDBDF_02135	9.11e-208	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
HAPGDBDF_02136	1.23e-58	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
HAPGDBDF_02137	5.31e-242	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HAPGDBDF_02138	3.88e-264	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
HAPGDBDF_02139	8.69e-230	citR	-	-	K	-	-	-	sugar-binding domain protein
HAPGDBDF_02140	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HAPGDBDF_02141	3.75e-214	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HAPGDBDF_02142	1.18e-66	-	-	-	-	-	-	-	-
HAPGDBDF_02143	1.73e-221	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HAPGDBDF_02144	3.54e-180	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HAPGDBDF_02145	8.31e-170	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HAPGDBDF_02146	1.57e-196	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HAPGDBDF_02147	1.28e-253	-	-	-	K	-	-	-	Helix-turn-helix domain
HAPGDBDF_02148	5.21e-226	ttdA	4.2.1.32	-	C	ko:K03779	ko00630,map00630	ko00000,ko00001,ko01000	Fumarate hydratase (Fumerase)
HAPGDBDF_02149	1.41e-147	-	4.2.1.2, 4.2.1.32	-	C	ko:K01676,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
HAPGDBDF_02150	4.33e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HAPGDBDF_02151	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HAPGDBDF_02152	1.23e-251	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HAPGDBDF_02153	5.47e-234	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	DAHP synthetase I family
HAPGDBDF_02154	2.25e-209	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HAPGDBDF_02155	0.0	tkt2	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HAPGDBDF_02156	1.35e-261	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HAPGDBDF_02157	2.46e-235	-	-	-	S	-	-	-	Membrane
HAPGDBDF_02158	5.75e-208	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HAPGDBDF_02159	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HAPGDBDF_02160	4.58e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HAPGDBDF_02161	3.06e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HAPGDBDF_02162	2.79e-183	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HAPGDBDF_02163	2.01e-211	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HAPGDBDF_02164	1.98e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HAPGDBDF_02165	1.07e-264	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HAPGDBDF_02166	3.19e-194	-	-	-	S	-	-	-	FMN_bind
HAPGDBDF_02167	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HAPGDBDF_02168	5.37e-112	-	-	-	S	-	-	-	NusG domain II
HAPGDBDF_02169	1.41e-122	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
HAPGDBDF_02170	1.02e-233	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HAPGDBDF_02171	7.76e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HAPGDBDF_02172	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAPGDBDF_02173	7.71e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HAPGDBDF_02174	9.65e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HAPGDBDF_02175	1.19e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HAPGDBDF_02176	1.84e-160	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HAPGDBDF_02177	5.95e-300	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HAPGDBDF_02178	1.32e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HAPGDBDF_02179	8.44e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HAPGDBDF_02180	5.32e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HAPGDBDF_02181	1.75e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HAPGDBDF_02182	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HAPGDBDF_02183	4.99e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HAPGDBDF_02184	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HAPGDBDF_02185	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HAPGDBDF_02186	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HAPGDBDF_02187	1.96e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HAPGDBDF_02188	1.11e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HAPGDBDF_02189	8.29e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HAPGDBDF_02190	5.46e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HAPGDBDF_02191	3.59e-69	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HAPGDBDF_02192	1.85e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HAPGDBDF_02193	6.61e-193	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HAPGDBDF_02194	2.27e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HAPGDBDF_02195	9.83e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HAPGDBDF_02196	4.34e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HAPGDBDF_02197	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HAPGDBDF_02198	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HAPGDBDF_02199	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HAPGDBDF_02200	4.19e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HAPGDBDF_02201	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAPGDBDF_02202	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAPGDBDF_02203	1.16e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAPGDBDF_02204	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HAPGDBDF_02205	9.78e-102	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HAPGDBDF_02213	1.62e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HAPGDBDF_02214	1.11e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HAPGDBDF_02215	1.29e-153	dacB	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HAPGDBDF_02216	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HAPGDBDF_02217	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HAPGDBDF_02218	9.82e-118	-	-	-	K	-	-	-	Transcriptional regulator
HAPGDBDF_02219	7.14e-128	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HAPGDBDF_02220	3.88e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HAPGDBDF_02221	4.15e-153	-	-	-	I	-	-	-	phosphatase
HAPGDBDF_02222	2.34e-242	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HAPGDBDF_02223	7.76e-100	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HAPGDBDF_02224	4.6e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
HAPGDBDF_02225	1.78e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HAPGDBDF_02226	2.94e-155	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HAPGDBDF_02227	1.36e-77	-	-	-	-	-	-	-	-
HAPGDBDF_02228	7.79e-112	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HAPGDBDF_02229	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HAPGDBDF_02230	2.72e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HAPGDBDF_02231	1.46e-170	-	-	-	-	-	-	-	-
HAPGDBDF_02232	1.75e-47	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HAPGDBDF_02233	8.25e-155	azlC	-	-	E	-	-	-	branched-chain amino acid
HAPGDBDF_02234	2.41e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HAPGDBDF_02235	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HAPGDBDF_02236	2.42e-281	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HAPGDBDF_02237	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HAPGDBDF_02238	0.0	xylP2	-	-	G	-	-	-	symporter
HAPGDBDF_02239	2.98e-246	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HAPGDBDF_02240	2.74e-63	-	-	-	-	-	-	-	-
HAPGDBDF_02241	1.5e-156	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
HAPGDBDF_02242	4.97e-132	-	-	-	K	-	-	-	FR47-like protein
HAPGDBDF_02243	8.44e-163	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HAPGDBDF_02244	1.89e-277	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HAPGDBDF_02245	1.86e-242	-	-	-	-	-	-	-	-
HAPGDBDF_02246	2.91e-179	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HAPGDBDF_02247	5.06e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HAPGDBDF_02248	9.95e-211	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HAPGDBDF_02249	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HAPGDBDF_02250	4.95e-44	-	-	-	L	-	-	-	leucine-zipper of insertion element IS481
HAPGDBDF_02251	9.05e-55	-	-	-	-	-	-	-	-
HAPGDBDF_02252	7.26e-275	-	-	-	L	-	-	-	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HAPGDBDF_02253	2.97e-51	-	-	-	L	-	-	-	Transposase DDE domain
HAPGDBDF_02254	4.9e-39	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HAPGDBDF_02255	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HAPGDBDF_02256	3.39e-255	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HAPGDBDF_02257	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HAPGDBDF_02258	4.71e-149	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HAPGDBDF_02259	4.13e-104	-	-	-	K	-	-	-	Transcriptional regulator
HAPGDBDF_02260	2.22e-169	-	-	-	L	-	-	-	Helix-turn-helix domain
HAPGDBDF_02261	7e-208	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HAPGDBDF_02263	0.0	-	-	-	C	-	-	-	FMN_bind
HAPGDBDF_02264	6.52e-219	-	-	-	K	-	-	-	Transcriptional regulator
HAPGDBDF_02265	1.05e-121	-	-	-	K	-	-	-	Helix-turn-helix domain
HAPGDBDF_02266	1.97e-175	-	-	-	K	-	-	-	sequence-specific DNA binding
HAPGDBDF_02267	1.27e-115	-	-	-	S	-	-	-	AAA domain
HAPGDBDF_02268	1.42e-08	-	-	-	-	-	-	-	-
HAPGDBDF_02269	0.0	-	-	-	M	-	-	-	MucBP domain
HAPGDBDF_02270	1.39e-118	XK27_09665	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
HAPGDBDF_02271	7.7e-226	-	-	-	L	ko:K07482	-	ko00000	Integrase core domain
HAPGDBDF_02272	1.23e-108	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HAPGDBDF_02273	1.44e-33	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
HAPGDBDF_02274	5.97e-61	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HAPGDBDF_02275	0.000211	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HAPGDBDF_02276	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HAPGDBDF_02277	2.34e-280	-	-	-	S	-	-	-	PglZ domain
HAPGDBDF_02278	3.73e-221	-	-	-	LV	-	-	-	Eco57I restriction-modification methylase
HAPGDBDF_02279	2.15e-189	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPGDBDF_02280	0.0	-	-	-	LV	-	-	-	Eco57I restriction-modification methylase
HAPGDBDF_02281	0.0	-	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
HAPGDBDF_02282	1.15e-93	-	-	-	S	-	-	-	Domain of unknown function (DUF1788)
HAPGDBDF_02283	3.07e-84	-	-	-	S	-	-	-	Putative inner membrane protein (DUF1819)
HAPGDBDF_02284	3.25e-181	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HAPGDBDF_02285	5.21e-62	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HAPGDBDF_02286	2.57e-212	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HAPGDBDF_02287	1.31e-188	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
HAPGDBDF_02288	3.96e-225	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HAPGDBDF_02289	1.04e-94	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HAPGDBDF_02290	1.1e-93	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HAPGDBDF_02291	5.74e-32	-	-	-	-	-	-	-	-
HAPGDBDF_02292	1.95e-116	-	-	-	-	-	-	-	-
HAPGDBDF_02293	1.81e-50	ydaS	-	-	S	-	-	-	Transglycosylase associated protein
HAPGDBDF_02294	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase family
HAPGDBDF_02295	8.49e-60	-	-	-	S	-	-	-	MORN repeat
HAPGDBDF_02296	6.35e-69	-	-	-	-	-	-	-	-
HAPGDBDF_02297	2.98e-97	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HAPGDBDF_02298	3.13e-99	-	-	-	L	-	-	-	Transposase DDE domain
HAPGDBDF_02299	2.74e-88	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HAPGDBDF_02300	2.35e-93	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HAPGDBDF_02301	6.46e-111	-	-	-	-	-	-	-	-
HAPGDBDF_02302	1.96e-117	-	-	-	D	-	-	-	nuclear chromosome segregation
HAPGDBDF_02303	1.59e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HAPGDBDF_02304	1.22e-242	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HAPGDBDF_02305	1.57e-140	XK27_07075	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HAPGDBDF_02306	8.89e-80	-	-	-	K	-	-	-	Helix-turn-helix domain
HAPGDBDF_02307	1.04e-69	-	-	-	-	-	-	-	-
HAPGDBDF_02308	3.01e-38	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HAPGDBDF_02309	9.75e-176	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
HAPGDBDF_02310	6.18e-130	-	-	-	K	-	-	-	Transcriptional regulator, AbiEi antitoxin
HAPGDBDF_02311	1.96e-81	-	-	-	L	-	-	-	AAA domain
HAPGDBDF_02314	3.66e-162	yeeC	-	-	P	-	-	-	T5orf172
HAPGDBDF_02315	0.0	-	-	-	L	-	-	-	DEAD-like helicases superfamily
HAPGDBDF_02316	3.61e-76	yeeA	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
HAPGDBDF_02317	0.0	yeeA	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
HAPGDBDF_02319	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HAPGDBDF_02320	1.22e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HAPGDBDF_02321	2.08e-211	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
HAPGDBDF_02322	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HAPGDBDF_02323	1.11e-143	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HAPGDBDF_02324	1.19e-226	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HAPGDBDF_02325	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HAPGDBDF_02326	2.07e-161	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
HAPGDBDF_02327	1.35e-165	pgm3	-	-	G	-	-	-	Phosphoglycerate mutase family
HAPGDBDF_02328	1.61e-36	-	-	-	-	-	-	-	-
HAPGDBDF_02329	7.7e-226	-	-	-	L	ko:K07482	-	ko00000	Integrase core domain
HAPGDBDF_02330	1.95e-61	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
HAPGDBDF_02331	4.6e-102	rppH3	-	-	F	-	-	-	NUDIX domain
HAPGDBDF_02332	1.7e-299	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HAPGDBDF_02333	1.81e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAPGDBDF_02334	2.93e-109	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HAPGDBDF_02335	3.22e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HAPGDBDF_02336	8.83e-93	-	-	-	K	-	-	-	MarR family
HAPGDBDF_02337	8.87e-191	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
HAPGDBDF_02338	1.26e-95	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HAPGDBDF_02339	0.0	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HAPGDBDF_02340	3.16e-182	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
HAPGDBDF_02341	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HAPGDBDF_02342	7.7e-226	-	-	-	L	ko:K07482	-	ko00000	Integrase core domain
HAPGDBDF_02343	1.8e-189	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HAPGDBDF_02344	2.1e-109	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HAPGDBDF_02345	1.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HAPGDBDF_02346	3.14e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HAPGDBDF_02347	3.39e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HAPGDBDF_02348	6.59e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HAPGDBDF_02350	5.2e-54	-	-	-	-	-	-	-	-
HAPGDBDF_02351	1.03e-217	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HAPGDBDF_02352	7.9e-269	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HAPGDBDF_02353	6.94e-146	gph1	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant
HAPGDBDF_02354	1.01e-188	-	-	-	-	-	-	-	-
HAPGDBDF_02355	8.84e-18	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HAPGDBDF_02356	2.02e-106	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HAPGDBDF_02357	2.45e-134	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HAPGDBDF_02358	1.48e-27	-	-	-	-	-	-	-	-
HAPGDBDF_02359	4.33e-95	-	-	-	F	-	-	-	Nudix hydrolase
HAPGDBDF_02360	1.23e-189	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HAPGDBDF_02361	6.12e-115	-	-	-	-	-	-	-	-
HAPGDBDF_02362	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HAPGDBDF_02363	1.09e-60	-	-	-	-	-	-	-	-
HAPGDBDF_02364	1.09e-89	-	-	-	O	-	-	-	OsmC-like protein
HAPGDBDF_02365	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HAPGDBDF_02366	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HAPGDBDF_02367	1.23e-229	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HAPGDBDF_02368	6.37e-232	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HAPGDBDF_02369	0.0	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HAPGDBDF_02370	1.06e-195	ribC1	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HAPGDBDF_02371	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HAPGDBDF_02372	1.79e-287	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HAPGDBDF_02373	1.36e-27	-	-	-	-	-	-	-	-
HAPGDBDF_02374	6.16e-107	-	-	-	K	-	-	-	Transcriptional regulator
HAPGDBDF_02375	6.68e-197	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HAPGDBDF_02376	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HAPGDBDF_02377	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HAPGDBDF_02378	4.45e-226	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HAPGDBDF_02379	1.02e-312	-	-	-	EGP	-	-	-	Major Facilitator
HAPGDBDF_02380	2.08e-117	-	-	-	V	-	-	-	VanZ like family
HAPGDBDF_02381	3.88e-46	-	-	-	-	-	-	-	-
HAPGDBDF_02382	5.45e-94	spx1	-	-	P	ko:K16509	-	ko00000	ArsC family
HAPGDBDF_02384	6.37e-186	-	-	-	-	-	-	-	-
HAPGDBDF_02385	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HAPGDBDF_02386	5.79e-196	-	-	-	G	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HAPGDBDF_02387	2.87e-168	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HAPGDBDF_02388	1.69e-93	-	-	-	-	-	-	-	-
HAPGDBDF_02389	3.38e-70	-	-	-	-	-	-	-	-
HAPGDBDF_02390	4.87e-262	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HAPGDBDF_02391	1.21e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAPGDBDF_02392	3.27e-189	-	3.1.3.23	-	S	ko:K07757	-	ko00000,ko01000	Sucrose-6F-phosphate phosphohydrolase
HAPGDBDF_02393	4.47e-158	-	-	-	T	-	-	-	EAL domain
HAPGDBDF_02394	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HAPGDBDF_02395	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HAPGDBDF_02396	2.18e-182	ybbR	-	-	S	-	-	-	YbbR-like protein
HAPGDBDF_02397	3.39e-191	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HAPGDBDF_02398	5.68e-156	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
HAPGDBDF_02399	3.07e-119	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HAPGDBDF_02400	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HAPGDBDF_02401	2.54e-213	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HAPGDBDF_02402	2.43e-210	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
HAPGDBDF_02403	1.03e-197	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HAPGDBDF_02404	2.41e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HAPGDBDF_02405	2.52e-114	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HAPGDBDF_02406	1.29e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HAPGDBDF_02407	5e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HAPGDBDF_02408	5.71e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HAPGDBDF_02409	1.98e-199	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HAPGDBDF_02410	1.04e-110	-	-	-	-	-	-	-	-
HAPGDBDF_02411	9.36e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HAPGDBDF_02412	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HAPGDBDF_02413	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HAPGDBDF_02414	9.78e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HAPGDBDF_02415	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HAPGDBDF_02416	6.35e-178	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
HAPGDBDF_02417	1.76e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HAPGDBDF_02418	2.05e-144	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HAPGDBDF_02419	6.4e-201	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HAPGDBDF_02420	2.42e-169	-	-	-	-	-	-	-	-
HAPGDBDF_02421	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HAPGDBDF_02422	7.15e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HAPGDBDF_02423	1.31e-285	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HAPGDBDF_02424	2.02e-245	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HAPGDBDF_02425	9.53e-241	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HAPGDBDF_02426	1.14e-311	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
HAPGDBDF_02428	5.11e-133	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HAPGDBDF_02429	3.64e-224	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HAPGDBDF_02430	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HAPGDBDF_02431	1.21e-215	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HAPGDBDF_02432	1.46e-239	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HAPGDBDF_02433	2e-206	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HAPGDBDF_02434	8.62e-114	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HAPGDBDF_02435	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HAPGDBDF_02436	3.06e-301	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HAPGDBDF_02437	2.21e-113	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HAPGDBDF_02438	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HAPGDBDF_02439	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HAPGDBDF_02440	3.85e-151	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HAPGDBDF_02441	5.33e-268	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
HAPGDBDF_02442	1.89e-134	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HAPGDBDF_02443	0.0	nox2	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HAPGDBDF_02444	2.4e-169	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HAPGDBDF_02445	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HAPGDBDF_02446	7.54e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HAPGDBDF_02447	4.31e-141	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HAPGDBDF_02448	8.65e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HAPGDBDF_02449	0.0	nox	-	-	C	-	-	-	NADH oxidase
HAPGDBDF_02450	3.69e-159	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HAPGDBDF_02451	1.13e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HAPGDBDF_02452	1.98e-235	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HAPGDBDF_02453	3.62e-212	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HAPGDBDF_02454	2.55e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HAPGDBDF_02455	6.77e-70	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HAPGDBDF_02456	2.78e-65	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
HAPGDBDF_02457	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HAPGDBDF_02458	2.69e-178	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HAPGDBDF_02459	9.78e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HAPGDBDF_02460	5.04e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HAPGDBDF_02461	4.48e-206	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HAPGDBDF_02462	6.91e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HAPGDBDF_02463	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HAPGDBDF_02464	3.52e-169	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HAPGDBDF_02465	1.05e-275	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HAPGDBDF_02466	3.33e-89	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HAPGDBDF_02467	6.08e-97	-	-	-	L	-	-	-	Transposase DDE domain
HAPGDBDF_02468	3.41e-257	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HAPGDBDF_02469	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HAPGDBDF_02470	1.27e-129	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HAPGDBDF_02471	2.94e-164	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HAPGDBDF_02472	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HAPGDBDF_02473	3.7e-149	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HAPGDBDF_02474	3.8e-198	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HAPGDBDF_02475	7.29e-247	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
HAPGDBDF_02476	0.0	ydaO	-	-	E	-	-	-	amino acid
HAPGDBDF_02477	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HAPGDBDF_02478	9.82e-55	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HAPGDBDF_02479	2.38e-140	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HAPGDBDF_02480	3.67e-154	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HAPGDBDF_02481	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HAPGDBDF_02482	3.62e-249	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HAPGDBDF_02483	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HAPGDBDF_02484	4.66e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HAPGDBDF_02485	6.84e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HAPGDBDF_02486	3.46e-242	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HAPGDBDF_02487	9.33e-177	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HAPGDBDF_02488	6.51e-178	phnE2	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter permease
HAPGDBDF_02489	3.33e-184	phnE1	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HAPGDBDF_02490	1.62e-186	phnX	3.11.1.1	-	E	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the HAD-like hydrolase superfamily. PhnX family
HAPGDBDF_02491	2.09e-267	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HAPGDBDF_02492	2.86e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HAPGDBDF_02493	3.17e-191	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HAPGDBDF_02494	1.26e-211	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HAPGDBDF_02495	8.46e-77	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HAPGDBDF_02496	2.33e-239	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HAPGDBDF_02497	1.39e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HAPGDBDF_02498	1.28e-152	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HAPGDBDF_02499	1.01e-51	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HAPGDBDF_02500	6.22e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HAPGDBDF_02501	2.05e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HAPGDBDF_02502	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HAPGDBDF_02503	7.57e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HAPGDBDF_02504	6.7e-141	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HAPGDBDF_02505	8.42e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HAPGDBDF_02506	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HAPGDBDF_02507	2.47e-253	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HAPGDBDF_02508	5.82e-141	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HAPGDBDF_02509	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HAPGDBDF_02510	3.32e-129	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
HAPGDBDF_02511	5.27e-34	-	-	-	L	-	-	-	nuclease
HAPGDBDF_02512	1.01e-226	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HAPGDBDF_02513	6.98e-100	-	-	-	O	-	-	-	Subtilase family
HAPGDBDF_02514	4.28e-65	-	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
HAPGDBDF_02515	7.54e-59	-	-	-	S	-	-	-	Bacteriophage holin
HAPGDBDF_02516	1.85e-49	-	-	-	S	-	-	-	Haemolysin XhlA
HAPGDBDF_02517	2.91e-253	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HAPGDBDF_02518	2.08e-32	-	-	-	-	-	-	-	-
HAPGDBDF_02519	2.03e-109	-	-	-	-	-	-	-	-
HAPGDBDF_02523	6.87e-69	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
HAPGDBDF_02524	4.27e-79	-	-	-	-	-	-	-	-
HAPGDBDF_02526	2.84e-123	-	-	-	S	-	-	-	Prophage endopeptidase tail
HAPGDBDF_02528	6.62e-179	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
HAPGDBDF_02531	9.58e-56	-	-	-	N	-	-	-	domain, Protein
HAPGDBDF_02536	0.000271	-	-	-	-	-	-	-	-
HAPGDBDF_02537	3.01e-136	-	-	-	-	-	-	-	-
HAPGDBDF_02539	1.42e-54	-	-	-	S	-	-	-	Phage minor capsid protein 2
HAPGDBDF_02540	2.67e-137	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HAPGDBDF_02541	4.23e-236	-	-	-	S	-	-	-	Phage terminase, large subunit, PBSX family
HAPGDBDF_02542	4.5e-61	-	-	-	L	-	-	-	transposase activity
HAPGDBDF_02544	1.68e-26	-	-	-	-	-	-	-	-
HAPGDBDF_02545	2.38e-60	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
HAPGDBDF_02546	3.16e-31	-	-	-	S	-	-	-	mRNA binding
HAPGDBDF_02551	2.77e-09	-	-	-	S	-	-	-	YopX protein
HAPGDBDF_02552	3.07e-284	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HAPGDBDF_02553	3.63e-21	-	-	-	S	-	-	-	YopX protein
HAPGDBDF_02555	2.37e-06	-	-	-	-	-	-	-	-
HAPGDBDF_02556	4.69e-86	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HAPGDBDF_02557	8.03e-107	-	-	-	-	-	-	-	-
HAPGDBDF_02558	1.23e-62	-	-	-	-	-	-	-	-
HAPGDBDF_02559	4.3e-206	-	-	-	L	-	-	-	DnaD domain protein
HAPGDBDF_02560	5.04e-77	-	-	-	-	-	-	-	-
HAPGDBDF_02561	1.39e-70	-	-	-	S	-	-	-	Bacteriophage Mu Gam like protein
HAPGDBDF_02565	6.53e-121	-	-	-	-	-	-	-	-
HAPGDBDF_02567	3.54e-43	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
HAPGDBDF_02570	5.01e-26	-	-	-	S	-	-	-	protein disulfide oxidoreductase activity
HAPGDBDF_02573	1.43e-231	-	-	-	S	ko:K07504	-	ko00000	Type I restriction enzyme R protein N terminus (HSDR_N)
HAPGDBDF_02576	4.44e-293	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPGDBDF_02578	2.76e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HAPGDBDF_02579	3.72e-105	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HAPGDBDF_02580	2.69e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HAPGDBDF_02581	9.76e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HAPGDBDF_02582	2.81e-202	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HAPGDBDF_02583	1.89e-128	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HAPGDBDF_02584	1e-39	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HAPGDBDF_02585	4.55e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HAPGDBDF_02586	1.12e-130	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
HAPGDBDF_02587	3.4e-126	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
HAPGDBDF_02588	1.49e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HAPGDBDF_02589	1.35e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HAPGDBDF_02590	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HAPGDBDF_02591	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HAPGDBDF_02592	4.91e-265	yacL	-	-	S	-	-	-	domain protein
HAPGDBDF_02593	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HAPGDBDF_02594	9.43e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HAPGDBDF_02595	5.96e-69	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HAPGDBDF_02596	1.62e-158	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HAPGDBDF_02597	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HAPGDBDF_02598	5.04e-149	zmp2	-	-	O	-	-	-	Zinc-dependent metalloprotease
HAPGDBDF_02599	1.91e-165	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HAPGDBDF_02600	8.57e-227	-	-	-	EG	-	-	-	EamA-like transporter family
HAPGDBDF_02601	7.53e-215	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HAPGDBDF_02602	2.29e-234	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HAPGDBDF_02603	1.23e-177	accA1	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
HAPGDBDF_02604	3.66e-184	accD1	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HAPGDBDF_02605	1.7e-315	accC1	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
HAPGDBDF_02606	9.24e-85	accB1	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin-requiring enzyme
HAPGDBDF_02607	3.67e-228	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HAPGDBDF_02608	4.5e-113	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HAPGDBDF_02609	7.19e-94	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HAPGDBDF_02610	0.0	levR	-	-	K	-	-	-	Sigma-54 interaction domain
HAPGDBDF_02611	9.05e-85	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
HAPGDBDF_02612	8.89e-218	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HAPGDBDF_02613	2.43e-174	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HAPGDBDF_02614	2.63e-217	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HAPGDBDF_02615	2.27e-197	-	-	-	G	-	-	-	Peptidase_C39 like family
HAPGDBDF_02617	8.77e-204	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HAPGDBDF_02618	1.71e-302	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HAPGDBDF_02619	5.34e-107	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HAPGDBDF_02620	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HAPGDBDF_02621	6.3e-95	-	-	-	-	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	-
HAPGDBDF_02622	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HAPGDBDF_02623	5.27e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HAPGDBDF_02624	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HAPGDBDF_02625	3.99e-177	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HAPGDBDF_02626	5.41e-160	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HAPGDBDF_02627	2.4e-279	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HAPGDBDF_02628	5.35e-175	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HAPGDBDF_02629	1.06e-195	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HAPGDBDF_02630	1.86e-246	ysdE	-	-	P	-	-	-	Citrate transporter
HAPGDBDF_02631	1.31e-213	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
HAPGDBDF_02632	1.38e-71	-	-	-	S	-	-	-	Cupin domain
HAPGDBDF_02633	5.21e-65	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
HAPGDBDF_02637	1.5e-194	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HAPGDBDF_02638	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HAPGDBDF_02641	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HAPGDBDF_02644	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HAPGDBDF_02645	5.33e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HAPGDBDF_02646	1.93e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HAPGDBDF_02647	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HAPGDBDF_02648	4.3e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HAPGDBDF_02649	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HAPGDBDF_02650	1.07e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HAPGDBDF_02651	2.02e-83	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HAPGDBDF_02653	7.72e-57	yabO	-	-	J	-	-	-	S4 domain protein
HAPGDBDF_02654	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HAPGDBDF_02655	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HAPGDBDF_02656	1.43e-129	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HAPGDBDF_02657	1.61e-225	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HAPGDBDF_02658	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HAPGDBDF_02659	4.87e-148	-	-	-	S	-	-	-	(CBS) domain
HAPGDBDF_02660	8.1e-157	pepL	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HAPGDBDF_02661	5.29e-211	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HAPGDBDF_02662	1.3e-110	queT	-	-	S	-	-	-	QueT transporter
HAPGDBDF_02663	2.63e-241	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HAPGDBDF_02664	4.28e-274	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
HAPGDBDF_02665	2.36e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HAPGDBDF_02666	3.39e-294	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HAPGDBDF_02667	3.61e-244	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HAPGDBDF_02668	2.61e-260	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HAPGDBDF_02669	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HAPGDBDF_02670	2.02e-171	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HAPGDBDF_02671	7.44e-203	-	-	-	U	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAPGDBDF_02672	1.13e-247	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	ABC transporter, substratebinding protein
HAPGDBDF_02673	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HAPGDBDF_02674	2.58e-85	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HAPGDBDF_02675	5e-275	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HAPGDBDF_02676	9.32e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HAPGDBDF_02677	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HAPGDBDF_02678	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HAPGDBDF_02679	1.84e-189	-	-	-	-	-	-	-	-
HAPGDBDF_02680	1.78e-191	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HAPGDBDF_02681	5.35e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HAPGDBDF_02682	3.14e-164	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HAPGDBDF_02683	1.49e-273	-	-	-	J	-	-	-	translation release factor activity
HAPGDBDF_02684	1.91e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HAPGDBDF_02685	6.26e-306	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HAPGDBDF_02686	2.08e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HAPGDBDF_02687	4.01e-36	-	-	-	-	-	-	-	-
HAPGDBDF_02688	6.59e-170	-	-	-	S	-	-	-	YheO-like PAS domain
HAPGDBDF_02689	9.4e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HAPGDBDF_02690	7.51e-159	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HAPGDBDF_02691	2.28e-290	sdaC	-	-	E	ko:K03837	-	ko00000,ko02000	amino acid
HAPGDBDF_02692	8.29e-312	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HAPGDBDF_02693	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HAPGDBDF_02694	2.96e-89	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HAPGDBDF_02695	5.8e-101	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HAPGDBDF_02696	6.05e-198	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
HAPGDBDF_02697	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HAPGDBDF_02698	1.45e-191	yxeH	-	-	S	-	-	-	hydrolase
HAPGDBDF_02699	2.49e-178	-	-	-	-	-	-	-	-
HAPGDBDF_02700	2.82e-236	-	-	-	S	-	-	-	DUF218 domain
HAPGDBDF_02701	3.26e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HAPGDBDF_02702	7.44e-192	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HAPGDBDF_02703	5.78e-292	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HAPGDBDF_02704	1.96e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HAPGDBDF_02705	6.2e-48	-	-	-	-	-	-	-	-
HAPGDBDF_02706	2.95e-57	-	-	-	S	-	-	-	ankyrin repeats
HAPGDBDF_02707	6.39e-169	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HAPGDBDF_02708	8.05e-166	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HAPGDBDF_02709	1.9e-230	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
HAPGDBDF_02710	2.26e-209	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HAPGDBDF_02711	6.87e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HAPGDBDF_02712	1.19e-201	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HAPGDBDF_02713	1.6e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HAPGDBDF_02714	1.34e-186	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HAPGDBDF_02715	2.74e-88	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HAPGDBDF_02716	3.13e-99	-	-	-	L	-	-	-	Transposase DDE domain
HAPGDBDF_02718	5.1e-106	mutR	-	-	K	ko:K20373,ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
HAPGDBDF_02719	1.81e-273	-	-	-	EGP	ko:K02030	-	ko00000,ko00002,ko02000	Drug resistance transporter Bcr CflA subfamily
HAPGDBDF_02720	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HAPGDBDF_02721	4.64e-92	-	-	-	F	-	-	-	DNA mismatch repair protein MutT
HAPGDBDF_02722	4.54e-205	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HAPGDBDF_02723	2.14e-171	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HAPGDBDF_02724	4.65e-229	-	-	-	-	-	-	-	-
HAPGDBDF_02725	1.37e-290	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HAPGDBDF_02726	1.36e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HAPGDBDF_02727	1.2e-243	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HAPGDBDF_02728	1.6e-77	chpA	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HAPGDBDF_02729	5.9e-46	-	-	-	-	-	-	-	-
HAPGDBDF_02730	5.67e-96	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HAPGDBDF_02731	9.68e-34	-	-	-	-	-	-	-	-
HAPGDBDF_02732	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HAPGDBDF_02733	2.69e-166	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HAPGDBDF_02734	2.35e-243	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HAPGDBDF_02735	5.87e-181	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HAPGDBDF_02736	0.0	-	-	-	L	-	-	-	DNA helicase
HAPGDBDF_02737	4.23e-64	axe	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
HAPGDBDF_02738	1.59e-145	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HAPGDBDF_02739	1.86e-143	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HAPGDBDF_02740	8.02e-152	plnU	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HAPGDBDF_02741	1.83e-140	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HAPGDBDF_02742	4.91e-103	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
HAPGDBDF_02743	6.09e-53	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
HAPGDBDF_02744	7.23e-202	is18	-	-	L	-	-	-	Integrase core domain
HAPGDBDF_02745	3.27e-81	-	-	-	-	-	-	-	-
HAPGDBDF_02746	5.87e-22	-	-	-	-	-	-	-	-
HAPGDBDF_02748	1.32e-29	-	-	-	-	-	-	-	-
HAPGDBDF_02749	5.89e-90	-	-	-	-	-	-	-	-
HAPGDBDF_02750	5.52e-64	-	-	-	U	-	-	-	nuclease activity
HAPGDBDF_02751	8.53e-28	-	-	-	-	-	-	-	-
HAPGDBDF_02752	1.3e-49	-	-	-	-	-	-	-	-
HAPGDBDF_02753	5.89e-131	-	-	-	S	-	-	-	ankyrin repeats
HAPGDBDF_02754	1.24e-11	-	-	-	S	-	-	-	Immunity protein 22
HAPGDBDF_02755	5.01e-226	-	-	-	-	-	-	-	-
HAPGDBDF_02756	1.82e-34	-	-	-	S	-	-	-	Immunity protein 74
HAPGDBDF_02757	8.33e-90	-	-	-	M	-	-	-	dTDP-4-dehydrorhamnose reductase activity
HAPGDBDF_02758	0.0	-	-	-	M	-	-	-	domain protein
HAPGDBDF_02759	2.14e-174	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HAPGDBDF_02760	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
HAPGDBDF_02761	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HAPGDBDF_02762	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HAPGDBDF_02763	2.7e-230	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HAPGDBDF_02764	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HAPGDBDF_02765	4.06e-102	-	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
HAPGDBDF_02766	2.42e-207	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HAPGDBDF_02767	1.49e-223	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HAPGDBDF_02768	3.45e-103	accB3	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HAPGDBDF_02769	2.16e-103	-	-	-	-	-	-	-	-
HAPGDBDF_02770	5.89e-108	-	-	-	K	-	-	-	Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HAPGDBDF_02771	1.96e-295	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HAPGDBDF_02772	5.33e-124	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HAPGDBDF_02773	5.34e-72	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HAPGDBDF_02774	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
HAPGDBDF_02775	6.87e-153	rpiA2	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HAPGDBDF_02776	1.05e-132	zmp1	-	-	O	-	-	-	Zinc-dependent metalloprotease
HAPGDBDF_02777	8.95e-60	-	-	-	-	-	-	-	-
HAPGDBDF_02778	7.39e-226	hicD1	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HAPGDBDF_02779	1.66e-305	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HAPGDBDF_02780	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
HAPGDBDF_02781	4.63e-119	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HAPGDBDF_02782	6.53e-58	-	-	-	-	-	-	-	-
HAPGDBDF_02783	9.42e-258	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HAPGDBDF_02784	8.13e-199	tagG	-	-	U	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HAPGDBDF_02785	1.1e-280	-	-	-	-	-	-	-	-
HAPGDBDF_02786	2.58e-283	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HAPGDBDF_02787	4.03e-81	-	-	-	S	-	-	-	CHY zinc finger
HAPGDBDF_02788	1.37e-223	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HAPGDBDF_02789	4.41e-123	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HAPGDBDF_02790	6.4e-54	-	-	-	-	-	-	-	-
HAPGDBDF_02791	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HAPGDBDF_02792	7.28e-42	-	-	-	-	-	-	-	-
HAPGDBDF_02793	1.43e-170	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HAPGDBDF_02794	5.55e-304	xylP1	-	-	G	-	-	-	MFS/sugar transport protein
HAPGDBDF_02796	8.16e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HAPGDBDF_02797	0.0	acdH	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
HAPGDBDF_02798	1.08e-243	-	-	-	-	-	-	-	-
HAPGDBDF_02799	7.53e-208	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HAPGDBDF_02800	5.05e-79	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HAPGDBDF_02801	2.06e-30	-	-	-	-	-	-	-	-
HAPGDBDF_02802	1.19e-114	-	-	-	K	-	-	-	acetyltransferase
HAPGDBDF_02803	1.88e-111	-	-	-	K	-	-	-	GNAT family
HAPGDBDF_02804	8.08e-110	-	-	-	S	-	-	-	ASCH
HAPGDBDF_02805	1.5e-124	-	-	-	K	-	-	-	Cupin domain
HAPGDBDF_02806	1.46e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HAPGDBDF_02807	3.14e-190	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HAPGDBDF_02808	1.31e-179	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HAPGDBDF_02809	3.07e-264	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HAPGDBDF_02810	2.18e-53	-	-	-	-	-	-	-	-
HAPGDBDF_02811	9.59e-288	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HAPGDBDF_02812	1.24e-99	-	-	-	K	-	-	-	Transcriptional regulator
HAPGDBDF_02813	1.26e-100	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HAPGDBDF_02814	9.17e-285	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HAPGDBDF_02815	3.01e-75	-	-	-	-	-	-	-	-
HAPGDBDF_02816	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
HAPGDBDF_02817	3.47e-47	-	-	-	-	-	-	-	-
HAPGDBDF_02818	9.74e-77	-	-	-	-	-	-	-	-
HAPGDBDF_02819	2.59e-228	-	-	-	-	-	-	-	-
HAPGDBDF_02820	2.43e-87	gcsH1	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Glycine cleavage H-protein
HAPGDBDF_02821	1.89e-94	-	-	-	M	-	-	-	LysM domain protein
HAPGDBDF_02822	3.13e-99	-	-	-	L	-	-	-	Transposase DDE domain
HAPGDBDF_02823	3.33e-89	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HAPGDBDF_02824	8.19e-74	-	-	-	M	-	-	-	Lysin motif
HAPGDBDF_02825	9.59e-157	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HAPGDBDF_02826	1.32e-170	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HAPGDBDF_02827	4.87e-156	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HAPGDBDF_02828	6.81e-291	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HAPGDBDF_02829	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HAPGDBDF_02830	5.62e-137	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HAPGDBDF_02831	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HAPGDBDF_02832	1.17e-135	-	-	-	K	-	-	-	transcriptional regulator
HAPGDBDF_02833	1.41e-141	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HAPGDBDF_02834	1.49e-63	-	-	-	-	-	-	-	-
HAPGDBDF_02835	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HAPGDBDF_02836	7.18e-236	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HAPGDBDF_02837	2.87e-56	-	-	-	-	-	-	-	-
HAPGDBDF_02838	3.05e-66	-	-	-	-	-	-	-	-
HAPGDBDF_02839	6.86e-311	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HAPGDBDF_02840	1.61e-166	yidA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HAPGDBDF_02841	2.42e-65	-	-	-	-	-	-	-	-
HAPGDBDF_02842	1.9e-165	rrp2	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HAPGDBDF_02843	0.0	hpk2	-	-	T	-	-	-	Histidine kinase
HAPGDBDF_02844	2.39e-31	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HAPGDBDF_02845	0.0	ydiC	-	-	EGP	-	-	-	Major Facilitator
HAPGDBDF_02846	1.55e-55	-	-	-	-	-	-	-	-
HAPGDBDF_02847	4.48e-52	-	-	-	-	-	-	-	-
HAPGDBDF_02848	1.15e-152	-	-	-	-	-	-	-	-
HAPGDBDF_02849	5.71e-301	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HAPGDBDF_02850	8.62e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAPGDBDF_02851	8.9e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
HAPGDBDF_02852	3.13e-99	-	-	-	L	-	-	-	Transposase DDE domain
HAPGDBDF_02853	3.33e-89	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HAPGDBDF_02854	2.73e-92	-	-	-	-	-	-	-	-
HAPGDBDF_02855	3.37e-129	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HAPGDBDF_02856	0.0	tagF2	2.7.8.12	-	H	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HAPGDBDF_02857	8.12e-306	tagB	2.7.8.12, 2.7.8.45	-	M	ko:K09809,ko:K21591	-	ko00000,ko01000	glycerophosphotransferase
HAPGDBDF_02858	1.21e-94	tagD	2.7.7.15, 2.7.7.39	-	IM	ko:K00968,ko:K00980	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Glycerol-3-phosphate cytidylyltransferase
HAPGDBDF_02859	6.12e-184	-	-	-	-	-	-	-	-
HAPGDBDF_02860	0.0	pts5ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HAPGDBDF_02861	0.0	pts4ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HAPGDBDF_02862	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HAPGDBDF_02863	1.68e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HAPGDBDF_02864	2.21e-56	-	-	-	-	-	-	-	-
HAPGDBDF_02865	7.55e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
HAPGDBDF_02866	1.27e-181	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HAPGDBDF_02867	6.72e-203	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HAPGDBDF_02868	7.54e-211	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HAPGDBDF_02869	1.17e-267	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HAPGDBDF_02870	2.13e-124	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
HAPGDBDF_02871	7.87e-243	-	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
HAPGDBDF_02872	1.22e-166	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
HAPGDBDF_02873	2.92e-258	selA	2.9.1.1	-	H	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	L-seryl-tRNA selenium transferase
HAPGDBDF_02874	5.16e-271	dho	3.5.2.3	-	S	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase family
HAPGDBDF_02875	9.23e-270	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HAPGDBDF_02876	6.14e-53	-	-	-	-	-	-	-	-
HAPGDBDF_02877	1.93e-289	pts3C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HAPGDBDF_02878	5.41e-159	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
HAPGDBDF_02879	2.21e-127	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
HAPGDBDF_02880	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HAPGDBDF_02881	1.2e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HAPGDBDF_02882	2.98e-90	-	-	-	-	-	-	-	-
HAPGDBDF_02883	1.22e-125	-	-	-	-	-	-	-	-
HAPGDBDF_02884	5.92e-67	-	-	-	-	-	-	-	-
HAPGDBDF_02885	1.96e-75	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HAPGDBDF_02886	2.84e-110	-	-	-	-	-	-	-	-
HAPGDBDF_02887	1.06e-281	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HAPGDBDF_02888	5.33e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HAPGDBDF_02889	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
HAPGDBDF_02890	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HAPGDBDF_02891	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HAPGDBDF_02892	4.94e-126	-	-	-	K	-	-	-	Helix-turn-helix domain
HAPGDBDF_02893	1.37e-283	-	-	-	C	-	-	-	FAD dependent oxidoreductase
HAPGDBDF_02894	9.01e-221	-	-	-	P	-	-	-	Major Facilitator Superfamily
HAPGDBDF_02895	3.16e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HAPGDBDF_02896	1.2e-91	-	-	-	-	-	-	-	-
HAPGDBDF_02897	1.28e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HAPGDBDF_02898	1.77e-200	dkgB	-	-	S	-	-	-	reductase
HAPGDBDF_02899	2.28e-114	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HAPGDBDF_02900	1.43e-131	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC transporter permease
HAPGDBDF_02901	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HAPGDBDF_02902	1.75e-149	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HAPGDBDF_02903	0.0	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
HAPGDBDF_02904	5.66e-74	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HAPGDBDF_02905	3.18e-77	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HAPGDBDF_02906	3.81e-18	-	-	-	-	-	-	-	-
HAPGDBDF_02907	1.29e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HAPGDBDF_02908	4.56e-210	fbpA	-	-	K	-	-	-	Domain of unknown function (DUF814)
HAPGDBDF_02909	1.35e-78	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HAPGDBDF_02910	6.33e-46	-	-	-	-	-	-	-	-
HAPGDBDF_02911	2.49e-229	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HAPGDBDF_02912	1.11e-146	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
HAPGDBDF_02913	1.24e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HAPGDBDF_02914	1.19e-277	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HAPGDBDF_02915	1.31e-102	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HAPGDBDF_02916	7.83e-38	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HAPGDBDF_02917	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HAPGDBDF_02918	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HAPGDBDF_02919	1.03e-201	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HAPGDBDF_02921	0.0	-	-	-	M	-	-	-	domain protein
HAPGDBDF_02922	2.22e-207	mleR	-	-	K	-	-	-	LysR substrate binding domain
HAPGDBDF_02923	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HAPGDBDF_02924	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HAPGDBDF_02925	1.92e-209	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HAPGDBDF_02926	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HAPGDBDF_02927	2.4e-230	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HAPGDBDF_02928	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HAPGDBDF_02929	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HAPGDBDF_02930	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HAPGDBDF_02931	1.54e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HAPGDBDF_02932	9.17e-52	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HAPGDBDF_02933	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
HAPGDBDF_02934	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HAPGDBDF_02935	2.44e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HAPGDBDF_02936	0.0	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
HAPGDBDF_02937	2.91e-190	malA	-	-	S	-	-	-	maltodextrose utilization protein MalA
HAPGDBDF_02938	2.83e-206	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HAPGDBDF_02939	3.74e-302	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAPGDBDF_02940	9.45e-299	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HAPGDBDF_02941	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HAPGDBDF_02942	1.83e-231	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HAPGDBDF_02943	2.65e-245	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HAPGDBDF_02944	4e-172	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HAPGDBDF_02945	6.76e-75	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
HAPGDBDF_02946	2.75e-131	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
HAPGDBDF_02947	1.58e-238	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
HAPGDBDF_02948	2.47e-101	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
HAPGDBDF_02949	1.14e-122	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
HAPGDBDF_02950	1.85e-121	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAPGDBDF_02951	2.04e-99	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HAPGDBDF_02952	0.0	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
HAPGDBDF_02953	8.03e-151	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HAPGDBDF_02954	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
HAPGDBDF_02955	6.03e-218	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HAPGDBDF_02956	1.01e-184	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HAPGDBDF_02957	3.37e-115	-	-	-	-	-	-	-	-
HAPGDBDF_02958	2.42e-89	-	-	-	-	-	-	-	-
HAPGDBDF_02959	2.97e-89	-	-	-	-	-	-	-	-
HAPGDBDF_02960	2.47e-179	-	-	-	-	-	-	-	-
HAPGDBDF_02961	4.14e-72	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HAPGDBDF_02962	4.37e-167	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HAPGDBDF_02964	2.57e-128	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HAPGDBDF_02965	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HAPGDBDF_02966	3.28e-193	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HAPGDBDF_02967	6.49e-268	-	-	-	C	-	-	-	Oxidoreductase
HAPGDBDF_02968	0.0	-	-	-	-	-	-	-	-
HAPGDBDF_02969	4.29e-102	-	-	-	-	-	-	-	-
HAPGDBDF_02970	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HAPGDBDF_02971	1.92e-106	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase like
HAPGDBDF_02972	1.36e-211	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo keto reductase
HAPGDBDF_02973	2.16e-204	morA	-	-	S	-	-	-	reductase
HAPGDBDF_02975	2.79e-274	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HAPGDBDF_02976	3.98e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HAPGDBDF_02977	5.38e-290	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HAPGDBDF_02978	5.43e-102	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HAPGDBDF_02979	3.99e-96	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HAPGDBDF_02980	2.11e-97	-	-	-	K	-	-	-	Transcriptional regulator
HAPGDBDF_02981	1.72e-142	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HAPGDBDF_02982	2.92e-38	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HAPGDBDF_02983	5.46e-183	-	-	-	F	-	-	-	Phosphorylase superfamily
HAPGDBDF_02984	0.0	pacL1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HAPGDBDF_02985	9.93e-127	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
HAPGDBDF_02986	5.67e-64	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HAPGDBDF_02987	1.23e-199	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HAPGDBDF_02988	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HAPGDBDF_02989	4.17e-191	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HAPGDBDF_02990	1.27e-159	-	-	-	-	-	-	-	-
HAPGDBDF_02991	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HAPGDBDF_02992	5.04e-109	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HAPGDBDF_02993	0.0	-	-	-	L	-	-	-	HIRAN domain
HAPGDBDF_02994	3.4e-174	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HAPGDBDF_02995	4.15e-261	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HAPGDBDF_02996	1.48e-140	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HAPGDBDF_02997	1.18e-188	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HAPGDBDF_02998	9.25e-176	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HAPGDBDF_02999	1.23e-227	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HAPGDBDF_03000	5.24e-193	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
HAPGDBDF_03001	1.19e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HAPGDBDF_03002	6.32e-99	larC2	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Protein of unknown function DUF111
HAPGDBDF_03003	2.03e-179	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HAPGDBDF_03004	2.65e-162	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
HAPGDBDF_03005	7.9e-306	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
HAPGDBDF_03006	1.39e-156	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
HAPGDBDF_03007	1.84e-235	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
HAPGDBDF_03008	9.79e-192	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HAPGDBDF_03009	4.29e-166	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HAPGDBDF_03010	1.67e-54	-	-	-	-	-	-	-	-
HAPGDBDF_03011	5.66e-184	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HAPGDBDF_03012	4.07e-05	-	-	-	-	-	-	-	-
HAPGDBDF_03013	2.4e-180	-	-	-	-	-	-	-	-
HAPGDBDF_03014	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HAPGDBDF_03015	2.38e-99	-	-	-	-	-	-	-	-
HAPGDBDF_03016	7.76e-181	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HAPGDBDF_03017	5.21e-214	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HAPGDBDF_03018	5.98e-302	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HAPGDBDF_03019	1.92e-67	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HAPGDBDF_03020	3.14e-230	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HAPGDBDF_03021	1.4e-162	-	-	-	S	-	-	-	DJ-1/PfpI family
HAPGDBDF_03022	7.65e-121	yfbM	-	-	K	-	-	-	FR47-like protein
HAPGDBDF_03023	4.28e-195	-	-	-	EG	-	-	-	EamA-like transporter family
HAPGDBDF_03024	1.15e-80	-	-	-	S	-	-	-	Protein of unknown function
HAPGDBDF_03025	7.44e-51	-	-	-	S	-	-	-	Protein of unknown function
HAPGDBDF_03026	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HAPGDBDF_03027	6.65e-152	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HAPGDBDF_03028	1.67e-220	-	-	-	K	-	-	-	WYL domain
HAPGDBDF_03029	4.35e-165	-	-	-	F	-	-	-	glutamine amidotransferase
HAPGDBDF_03030	1.36e-105	-	-	-	S	-	-	-	ASCH
HAPGDBDF_03031	0.0	hpaH	1.14.14.8, 1.14.14.9	-	Q	ko:K00483,ko:K16901	ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220	ko00000,ko00001,ko01000	4-hydroxyphenylacetate
HAPGDBDF_03032	6.86e-175	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HAPGDBDF_03033	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HAPGDBDF_03034	1.04e-246	pva1	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HAPGDBDF_03035	1.56e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HAPGDBDF_03036	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HAPGDBDF_03037	5.07e-157	ydgI	-	-	C	-	-	-	Nitroreductase family
HAPGDBDF_03038	5.74e-204	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
HAPGDBDF_03039	1.66e-210	-	-	-	S	-	-	-	KR domain
HAPGDBDF_03040	4.48e-98	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HAPGDBDF_03041	2.49e-95	-	-	-	C	-	-	-	FMN binding
HAPGDBDF_03042	1.46e-204	-	-	-	K	-	-	-	LysR family
HAPGDBDF_03043	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HAPGDBDF_03044	0.0	-	-	-	C	-	-	-	FMN_bind
HAPGDBDF_03045	4.5e-150	-	-	-	S	-	-	-	Elongation factor G-binding protein, N-terminal
HAPGDBDF_03046	4.95e-86	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
HAPGDBDF_03047	1.34e-153	pnb	-	-	C	-	-	-	nitroreductase
HAPGDBDF_03048	5.97e-157	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HAPGDBDF_03049	8.48e-215	-	-	-	L	-	-	-	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HAPGDBDF_03050	0.0	-	-	-	C	-	-	-	Belongs to the aldehyde dehydrogenase family
HAPGDBDF_03051	2.84e-123	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAPGDBDF_03052	6.08e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HAPGDBDF_03053	1.5e-253	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HAPGDBDF_03054	1.71e-200	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HAPGDBDF_03055	3.54e-195	yycI	-	-	S	-	-	-	YycH protein
HAPGDBDF_03056	3.55e-313	yycH	-	-	S	-	-	-	YycH protein
HAPGDBDF_03057	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HAPGDBDF_03058	2.22e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HAPGDBDF_03060	2.54e-50	-	-	-	-	-	-	-	-
HAPGDBDF_03061	4.37e-43	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein domain
HAPGDBDF_03062	3.21e-104	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
HAPGDBDF_03063	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
HAPGDBDF_03064	2.59e-153	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HAPGDBDF_03065	2.4e-183	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HAPGDBDF_03067	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HAPGDBDF_03068	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HAPGDBDF_03069	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HAPGDBDF_03070	3.49e-269	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HAPGDBDF_03071	5.02e-277	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HAPGDBDF_03072	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HAPGDBDF_03073	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HAPGDBDF_03075	1.88e-291	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HAPGDBDF_03076	9e-184	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HAPGDBDF_03077	4.96e-289	yttB	-	-	EGP	-	-	-	Major Facilitator
HAPGDBDF_03078	8.77e-317	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HAPGDBDF_03079	3.44e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HAPGDBDF_03080	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HAPGDBDF_03081	2.69e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HAPGDBDF_03082	1.59e-95	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HAPGDBDF_03083	1.71e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HAPGDBDF_03084	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HAPGDBDF_03085	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HAPGDBDF_03086	7.24e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HAPGDBDF_03087	3.82e-51	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HAPGDBDF_03088	3.34e-266	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HAPGDBDF_03089	8.95e-315	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HAPGDBDF_03090	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HAPGDBDF_03091	7.87e-183	is18	-	-	L	-	-	-	Integrase core domain
HAPGDBDF_03092	2.48e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
HAPGDBDF_03093	4.62e-110	-	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
HAPGDBDF_03096	0.0	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HAPGDBDF_03097	1.49e-73	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HAPGDBDF_03098	5.82e-124	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
HAPGDBDF_03099	3.06e-280	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HAPGDBDF_03100	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HAPGDBDF_03101	8.37e-109	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HAPGDBDF_03102	9.1e-206	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HAPGDBDF_03103	5.54e-88	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HAPGDBDF_03104	7.39e-98	-	-	-	L	-	-	-	Transposase DDE domain
HAPGDBDF_03105	2.24e-246	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HAPGDBDF_03106	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HAPGDBDF_03107	8.27e-182	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
HAPGDBDF_03108	1.82e-55	-	-	-	M	-	-	-	LysM domain protein
HAPGDBDF_03109	1.21e-240	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
HAPGDBDF_03110	2.97e-234	gbuA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
HAPGDBDF_03111	4.63e-143	gbuB	-	-	E	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HAPGDBDF_03112	1.06e-124	gbuC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HAPGDBDF_03113	3.86e-109	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HAPGDBDF_03114	5.22e-74	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HAPGDBDF_03115	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HAPGDBDF_03116	8.22e-130	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HAPGDBDF_03117	1.02e-25	-	-	-	K	ko:K07729	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HAPGDBDF_03119	1e-61	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
HAPGDBDF_03120	1.14e-189	-	-	-	-	-	-	-	-
HAPGDBDF_03121	3.12e-270	-	-	-	EGP	-	-	-	Major Facilitator
HAPGDBDF_03122	2.76e-142	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HAPGDBDF_03123	5.16e-09	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	adenosylhomocysteinase activity
HAPGDBDF_03124	7.07e-106	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
HAPGDBDF_03125	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HAPGDBDF_03126	1.26e-216	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
HAPGDBDF_03127	6.91e-234	-	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
HAPGDBDF_03128	1.23e-62	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HAPGDBDF_03129	1.36e-304	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
HAPGDBDF_03130	9.89e-199	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HAPGDBDF_03131	5.85e-225	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HAPGDBDF_03132	2.15e-93	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
HAPGDBDF_03133	2.84e-257	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HAPGDBDF_03134	3.33e-210	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HAPGDBDF_03135	5.6e-114	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
HAPGDBDF_03136	1.01e-117	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
HAPGDBDF_03137	1.45e-281	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HAPGDBDF_03138	2.44e-46	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HAPGDBDF_03139	5.81e-88	-	-	-	L	-	-	-	Transposase
HAPGDBDF_03140	5.8e-46	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HAPGDBDF_03141	6.47e-52	-	-	-	KLT	-	-	-	serine threonine protein kinase
HAPGDBDF_03142	8.88e-45	-	-	-	-	-	-	-	-
HAPGDBDF_03143	3.41e-47	-	-	-	-	-	-	-	-
HAPGDBDF_03144	1.57e-296	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HAPGDBDF_03145	9.35e-25	-	-	-	-	-	-	-	-
HAPGDBDF_03147	3.05e-174	-	-	-	D	-	-	-	Cellulose biosynthesis protein BcsQ
HAPGDBDF_03148	3.95e-116	repE	-	-	K	-	-	-	Primase C terminal 1 (PriCT-1)
HAPGDBDF_03149	4.9e-39	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HAPGDBDF_03150	2.97e-51	-	-	-	L	-	-	-	Transposase DDE domain
HAPGDBDF_03153	2.19e-103	repA	-	-	S	-	-	-	Replication initiator protein A
HAPGDBDF_03154	2.83e-58	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
HAPGDBDF_03155	3.07e-109	-	-	-	-	-	-	-	-
HAPGDBDF_03156	4.21e-55	-	-	-	-	-	-	-	-
HAPGDBDF_03157	1.98e-36	-	-	-	-	-	-	-	-
HAPGDBDF_03158	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
HAPGDBDF_03160	2.74e-99	-	-	-	-	-	-	-	-
HAPGDBDF_03161	1.49e-64	-	-	-	S	-	-	-	Cag pathogenicity island, type IV secretory system
HAPGDBDF_03162	8.94e-70	-	-	-	-	-	-	-	-
HAPGDBDF_03163	4.48e-152	-	-	-	-	-	-	-	-
HAPGDBDF_03164	0.0	traE	-	-	U	-	-	-	Psort location Cytoplasmic, score
HAPGDBDF_03165	5.51e-303	-	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
HAPGDBDF_03166	7.88e-209	-	-	-	M	-	-	-	CHAP domain
HAPGDBDF_03167	2.17e-76	-	-	-	-	-	-	-	-
HAPGDBDF_03168	9.67e-59	-	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
HAPGDBDF_03169	3.88e-87	-	-	-	-	-	-	-	-
HAPGDBDF_03170	1.85e-294	traK	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
HAPGDBDF_03172	6.64e-95	-	-	-	-	-	-	-	-
HAPGDBDF_03173	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HAPGDBDF_03174	4.53e-45	-	-	-	-	-	-	-	-
HAPGDBDF_03175	1.07e-155	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HAPGDBDF_03176	2.85e-64	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HAPGDBDF_03177	1.37e-30	-	-	-	-	-	-	-	-
HAPGDBDF_03178	1.6e-97	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HAPGDBDF_03179	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HAPGDBDF_03180	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HAPGDBDF_03181	7.87e-183	is18	-	-	L	-	-	-	Integrase core domain
HAPGDBDF_03182	2.48e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
HAPGDBDF_03183	4.62e-110	-	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
HAPGDBDF_03184	1.01e-88	-	-	-	S	-	-	-	Fic/DOC family
HAPGDBDF_03185	1.38e-52	-	-	-	S	-	-	-	Fic/DOC family
HAPGDBDF_03186	3.34e-52	-	-	-	-	-	-	-	-
HAPGDBDF_03187	1.39e-36	-	-	-	-	-	-	-	-
HAPGDBDF_03188	7.75e-193	traA	-	-	L	-	-	-	MobA MobL family protein
HAPGDBDF_03189	1.51e-279	-	-	-	D	-	-	-	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HAPGDBDF_03190	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HAPGDBDF_03191	2.09e-41	-	-	-	-	-	-	-	-
HAPGDBDF_03192	1.45e-235	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HAPGDBDF_03193	3.59e-26	-	-	-	-	-	-	-	-