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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HDDNOHNL_00001	1.66e-101	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HDDNOHNL_00002	3.46e-267	mccF	-	-	V	-	-	-	LD-carboxypeptidase
HDDNOHNL_00003	9.63e-307	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HDDNOHNL_00004	9.19e-95	-	-	-	S	-	-	-	SnoaL-like domain
HDDNOHNL_00005	4.17e-186	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HDDNOHNL_00006	1.55e-309	-	-	-	P	-	-	-	Major Facilitator Superfamily
HDDNOHNL_00007	1.26e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HDDNOHNL_00008	1.44e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HDDNOHNL_00010	9.98e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HDDNOHNL_00011	2.12e-142	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HDDNOHNL_00012	3.6e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HDDNOHNL_00013	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HDDNOHNL_00014	4.64e-228	phnT	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HDDNOHNL_00015	8.06e-234	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HDDNOHNL_00016	0.0	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDDNOHNL_00017	5.32e-109	-	-	-	T	-	-	-	Universal stress protein family
HDDNOHNL_00018	1.58e-203	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HDDNOHNL_00019	2.45e-142	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDDNOHNL_00020	2.32e-238	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HDDNOHNL_00022	9.32e-165	dnaD	-	-	L	ko:K02086	-	ko00000	Replication initiation and membrane attachment
HDDNOHNL_00023	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HDDNOHNL_00024	3.1e-289	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HDDNOHNL_00025	2.53e-107	ypmB	-	-	S	-	-	-	protein conserved in bacteria
HDDNOHNL_00026	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HDDNOHNL_00027	1.48e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HDDNOHNL_00028	1.1e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HDDNOHNL_00029	2.94e-261	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HDDNOHNL_00030	8.61e-251	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HDDNOHNL_00031	3.36e-247	galM2	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HDDNOHNL_00032	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HDDNOHNL_00033	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HDDNOHNL_00034	3.24e-155	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HDDNOHNL_00035	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HDDNOHNL_00036	3.86e-192	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HDDNOHNL_00037	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HDDNOHNL_00038	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HDDNOHNL_00039	3.23e-58	-	-	-	-	-	-	-	-
HDDNOHNL_00040	1.25e-66	-	-	-	-	-	-	-	-
HDDNOHNL_00041	5.03e-182	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
HDDNOHNL_00042	1.48e-218	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HDDNOHNL_00043	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HDDNOHNL_00044	8.39e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HDDNOHNL_00045	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HDDNOHNL_00046	1.06e-53	-	-	-	-	-	-	-	-
HDDNOHNL_00047	4e-40	-	-	-	S	-	-	-	CsbD-like
HDDNOHNL_00048	2.22e-55	-	-	-	S	-	-	-	transglycosylase associated protein
HDDNOHNL_00049	5.79e-21	-	-	-	-	-	-	-	-
HDDNOHNL_00050	8.76e-48	-	-	-	-	-	-	-	-
HDDNOHNL_00051	1.21e-209	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HDDNOHNL_00052	5.58e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HDDNOHNL_00053	5.28e-100	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HDDNOHNL_00054	6.05e-108	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
HDDNOHNL_00055	2.05e-55	-	-	-	-	-	-	-	-
HDDNOHNL_00056	5.93e-60	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HDDNOHNL_00057	9.96e-147	-	1.14.99.53	AA10	S	ko:K21713	-	ko00000,ko01000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
HDDNOHNL_00058	3.2e-37	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HDDNOHNL_00059	6.57e-274	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HDDNOHNL_00060	2.02e-39	-	-	-	-	-	-	-	-
HDDNOHNL_00061	1.48e-71	-	-	-	-	-	-	-	-
HDDNOHNL_00062	1.14e-193	-	-	-	O	-	-	-	Band 7 protein
HDDNOHNL_00063	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HDDNOHNL_00064	4.09e-119	-	-	-	K	-	-	-	transcriptional regulator
HDDNOHNL_00065	4.4e-246	rsgA_2	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HDDNOHNL_00066	2.01e-113	ykhA	-	-	I	-	-	-	Thioesterase superfamily
HDDNOHNL_00067	7.52e-207	-	-	-	K	-	-	-	LysR substrate binding domain
HDDNOHNL_00068	1.48e-161	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HDDNOHNL_00069	5.01e-129	-	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
HDDNOHNL_00070	2.29e-175	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HDDNOHNL_00071	4.82e-179	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HDDNOHNL_00072	6.43e-203	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HDDNOHNL_00073	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HDDNOHNL_00074	1.71e-91	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HDDNOHNL_00075	2.14e-95	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HDDNOHNL_00076	1.8e-288	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HDDNOHNL_00077	1.26e-162	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HDDNOHNL_00078	3.47e-215	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HDDNOHNL_00079	6.16e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HDDNOHNL_00080	1.62e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HDDNOHNL_00081	8.55e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HDDNOHNL_00082	1.62e-229	yneE	-	-	K	-	-	-	Transcriptional regulator
HDDNOHNL_00083	6.84e-186	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDDNOHNL_00085	1.49e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HDDNOHNL_00086	2.69e-252	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HDDNOHNL_00087	3.38e-274	hipO1	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	Peptidase family M20/M25/M40
HDDNOHNL_00088	1.62e-276	-	-	-	E	-	-	-	glutamate:sodium symporter activity
HDDNOHNL_00089	1.95e-88	ybbJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HDDNOHNL_00090	1.36e-210	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
HDDNOHNL_00091	5.89e-126	entB	-	-	Q	-	-	-	Isochorismatase family
HDDNOHNL_00092	4.82e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HDDNOHNL_00093	5.13e-287	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HDDNOHNL_00094	1.57e-142	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HDDNOHNL_00095	2.41e-165	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HDDNOHNL_00096	6.03e-226	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HDDNOHNL_00097	8.08e-135	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
HDDNOHNL_00098	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
HDDNOHNL_00100	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HDDNOHNL_00101	2.05e-179	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HDDNOHNL_00102	9.06e-112	-	-	-	-	-	-	-	-
HDDNOHNL_00103	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HDDNOHNL_00104	3.2e-70	-	-	-	-	-	-	-	-
HDDNOHNL_00105	3.15e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HDDNOHNL_00106	1.57e-179	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HDDNOHNL_00107	6.42e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HDDNOHNL_00108	9.99e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HDDNOHNL_00109	1.6e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HDDNOHNL_00110	7.69e-300	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HDDNOHNL_00111	1.46e-77	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HDDNOHNL_00112	2.85e-293	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HDDNOHNL_00113	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HDDNOHNL_00114	4.49e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HDDNOHNL_00115	3.33e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HDDNOHNL_00116	2.17e-244	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HDDNOHNL_00117	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HDDNOHNL_00118	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HDDNOHNL_00119	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HDDNOHNL_00120	1.61e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HDDNOHNL_00121	1.84e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HDDNOHNL_00122	3.16e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HDDNOHNL_00123	1.21e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HDDNOHNL_00124	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HDDNOHNL_00125	1.62e-173	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HDDNOHNL_00126	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HDDNOHNL_00127	1.01e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HDDNOHNL_00128	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HDDNOHNL_00129	1.02e-277	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HDDNOHNL_00130	3.93e-41	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HDDNOHNL_00131	6.96e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HDDNOHNL_00132	8.28e-73	-	-	-	-	-	-	-	-
HDDNOHNL_00133	1.36e-136	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDDNOHNL_00134	3.8e-224	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HDDNOHNL_00135	7.11e-135	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDDNOHNL_00136	4.51e-284	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HDDNOHNL_00137	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HDDNOHNL_00138	2.15e-99	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HDDNOHNL_00139	4.49e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HDDNOHNL_00140	7.16e-201	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HDDNOHNL_00141	7.55e-44	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HDDNOHNL_00142	3.28e-312	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HDDNOHNL_00143	4.82e-194	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HDDNOHNL_00144	2.82e-91	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HDDNOHNL_00145	1.7e-96	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HDDNOHNL_00146	1.43e-129	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HDDNOHNL_00147	4.08e-247	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HDDNOHNL_00148	2.33e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HDDNOHNL_00149	7.97e-71	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HDDNOHNL_00150	1.55e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HDDNOHNL_00151	8.15e-125	-	-	-	K	-	-	-	Transcriptional regulator
HDDNOHNL_00152	9.81e-27	-	-	-	-	-	-	-	-
HDDNOHNL_00155	2.97e-41	-	-	-	-	-	-	-	-
HDDNOHNL_00156	3.11e-73	-	-	-	-	-	-	-	-
HDDNOHNL_00157	2.92e-126	-	-	-	S	-	-	-	Protein conserved in bacteria
HDDNOHNL_00158	1.34e-232	-	-	-	-	-	-	-	-
HDDNOHNL_00159	5.08e-205	-	-	-	-	-	-	-	-
HDDNOHNL_00160	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HDDNOHNL_00161	7.79e-85	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
HDDNOHNL_00162	3.8e-224	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HDDNOHNL_00163	7.77e-179	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HDDNOHNL_00164	1.44e-31	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HDDNOHNL_00165	1.15e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HDDNOHNL_00166	1.62e-141	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HDDNOHNL_00167	2.6e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HDDNOHNL_00168	6.33e-46	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HDDNOHNL_00169	3.52e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HDDNOHNL_00170	9.29e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HDDNOHNL_00171	5.33e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HDDNOHNL_00172	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HDDNOHNL_00173	0.0	-	-	-	S	-	-	-	membrane
HDDNOHNL_00174	6.12e-72	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HDDNOHNL_00175	5.72e-99	-	-	-	K	-	-	-	LytTr DNA-binding domain
HDDNOHNL_00176	9.72e-146	-	-	-	S	-	-	-	membrane
HDDNOHNL_00177	1.09e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HDDNOHNL_00178	7.5e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HDDNOHNL_00179	6.11e-249	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HDDNOHNL_00180	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HDDNOHNL_00181	6.88e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HDDNOHNL_00182	2.58e-82	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HDDNOHNL_00183	4.46e-179	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDDNOHNL_00184	1.37e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HDDNOHNL_00185	6.94e-209	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HDDNOHNL_00186	4.18e-121	-	-	-	S	-	-	-	SdpI/YhfL protein family
HDDNOHNL_00187	1.36e-288	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HDDNOHNL_00188	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HDDNOHNL_00189	1.93e-218	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HDDNOHNL_00190	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDDNOHNL_00191	1.38e-155	csrR	-	-	K	-	-	-	response regulator
HDDNOHNL_00192	2.56e-310	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HDDNOHNL_00193	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HDDNOHNL_00194	1.09e-223	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HDDNOHNL_00195	3.06e-124	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HDDNOHNL_00196	3.66e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HDDNOHNL_00197	3.04e-280	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HDDNOHNL_00198	3.3e-180	yqeM	-	-	Q	-	-	-	Methyltransferase
HDDNOHNL_00199	1.06e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HDDNOHNL_00200	1.71e-149	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HDDNOHNL_00201	4.19e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HDDNOHNL_00202	2.19e-67	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HDDNOHNL_00203	3.81e-276	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HDDNOHNL_00204	5.7e-127	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HDDNOHNL_00205	6.32e-114	-	-	-	-	-	-	-	-
HDDNOHNL_00206	3.97e-174	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HDDNOHNL_00207	1.64e-83	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HDDNOHNL_00208	1.18e-250	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HDDNOHNL_00209	7.03e-307	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
HDDNOHNL_00210	4.59e-73	-	-	-	-	-	-	-	-
HDDNOHNL_00211	6.88e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HDDNOHNL_00212	6.92e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HDDNOHNL_00213	2.37e-109	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HDDNOHNL_00214	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HDDNOHNL_00215	3.5e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HDDNOHNL_00216	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HDDNOHNL_00217	1.58e-117	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HDDNOHNL_00218	1.92e-133	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HDDNOHNL_00219	3.19e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HDDNOHNL_00220	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HDDNOHNL_00221	8.51e-155	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HDDNOHNL_00222	1.04e-141	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HDDNOHNL_00223	4.07e-60	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HDDNOHNL_00224	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HDDNOHNL_00225	2.71e-108	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HDDNOHNL_00226	1.11e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HDDNOHNL_00227	5.21e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HDDNOHNL_00228	1.1e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HDDNOHNL_00229	2.87e-47	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
HDDNOHNL_00230	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HDDNOHNL_00231	3.04e-29	-	-	-	S	-	-	-	Virus attachment protein p12 family
HDDNOHNL_00232	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HDDNOHNL_00233	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HDDNOHNL_00234	1.29e-148	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HDDNOHNL_00235	2.94e-71	ytzB	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HDDNOHNL_00236	2.8e-155	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HDDNOHNL_00237	7.24e-197	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
HDDNOHNL_00238	8.17e-285	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HDDNOHNL_00239	1.1e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDDNOHNL_00240	3.6e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HDDNOHNL_00241	6.76e-73	-	-	-	-	-	-	-	-
HDDNOHNL_00242	1.09e-196	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HDDNOHNL_00243	1.78e-153	draG	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HDDNOHNL_00244	5.76e-135	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HDDNOHNL_00245	2.82e-138	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HDDNOHNL_00246	1.94e-247	-	-	-	S	-	-	-	Fn3-like domain
HDDNOHNL_00247	1.65e-80	-	-	-	-	-	-	-	-
HDDNOHNL_00248	0.0	-	-	-	-	-	-	-	-
HDDNOHNL_00249	4.26e-308	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HDDNOHNL_00250	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HDDNOHNL_00251	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HDDNOHNL_00252	2.18e-182	ybbR	-	-	S	-	-	-	YbbR-like protein
HDDNOHNL_00253	2.39e-191	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HDDNOHNL_00254	8.06e-156	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
HDDNOHNL_00255	3.07e-119	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDDNOHNL_00256	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HDDNOHNL_00257	6.24e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HDDNOHNL_00258	3.09e-213	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
HDDNOHNL_00259	2.53e-198	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HDDNOHNL_00260	2.41e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HDDNOHNL_00261	2.52e-114	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HDDNOHNL_00262	1.29e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HDDNOHNL_00263	1.23e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HDDNOHNL_00264	1.4e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HDDNOHNL_00265	1.98e-199	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HDDNOHNL_00266	7.98e-137	-	-	-	-	-	-	-	-
HDDNOHNL_00267	9.36e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HDDNOHNL_00268	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDDNOHNL_00269	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HDDNOHNL_00270	2.4e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HDDNOHNL_00271	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HDDNOHNL_00272	3.83e-179	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
HDDNOHNL_00273	3.55e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HDDNOHNL_00274	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HDDNOHNL_00275	2.83e-168	-	-	-	-	-	-	-	-
HDDNOHNL_00276	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HDDNOHNL_00277	7.15e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HDDNOHNL_00278	1.31e-285	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HDDNOHNL_00279	2.02e-245	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HDDNOHNL_00280	5.75e-242	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HDDNOHNL_00281	1.14e-311	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
HDDNOHNL_00283	5.11e-133	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HDDNOHNL_00284	8.58e-223	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDDNOHNL_00285	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HDDNOHNL_00286	1.21e-215	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HDDNOHNL_00287	5.32e-242	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HDDNOHNL_00288	1.71e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HDDNOHNL_00289	3.51e-113	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HDDNOHNL_00290	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HDDNOHNL_00291	7.5e-302	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HDDNOHNL_00292	2.21e-113	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HDDNOHNL_00293	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HDDNOHNL_00294	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HDDNOHNL_00295	3.85e-151	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HDDNOHNL_00296	5.33e-268	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
HDDNOHNL_00297	1.89e-134	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HDDNOHNL_00298	0.0	nox2	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HDDNOHNL_00299	5.9e-170	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HDDNOHNL_00300	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HDDNOHNL_00301	7.54e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HDDNOHNL_00302	4.31e-141	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HDDNOHNL_00303	8.65e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HDDNOHNL_00304	0.0	nox	-	-	C	-	-	-	NADH oxidase
HDDNOHNL_00305	6.37e-160	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HDDNOHNL_00306	1.13e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HDDNOHNL_00307	4e-235	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HDDNOHNL_00308	6.26e-213	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HDDNOHNL_00309	2.55e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HDDNOHNL_00310	2.87e-71	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HDDNOHNL_00311	2.78e-65	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
HDDNOHNL_00312	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HDDNOHNL_00313	4.47e-177	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HDDNOHNL_00314	9.78e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HDDNOHNL_00315	5.04e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HDDNOHNL_00316	9.05e-206	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HDDNOHNL_00317	2.31e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HDDNOHNL_00318	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDDNOHNL_00319	1.49e-170	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HDDNOHNL_00320	1.05e-275	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HDDNOHNL_00321	3.41e-257	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HDDNOHNL_00322	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HDDNOHNL_00323	1.27e-129	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HDDNOHNL_00324	2.94e-164	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HDDNOHNL_00325	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HDDNOHNL_00326	3.7e-149	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HDDNOHNL_00327	6.57e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HDDNOHNL_00328	7.29e-247	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
HDDNOHNL_00329	0.0	ydaO	-	-	E	-	-	-	amino acid
HDDNOHNL_00330	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HDDNOHNL_00331	9.82e-55	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HDDNOHNL_00332	2.38e-140	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HDDNOHNL_00333	3.67e-154	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HDDNOHNL_00334	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HDDNOHNL_00335	3.62e-249	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HDDNOHNL_00336	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HDDNOHNL_00337	4.66e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HDDNOHNL_00338	6.84e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HDDNOHNL_00339	3.46e-242	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HDDNOHNL_00340	3.8e-176	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HDDNOHNL_00341	2.18e-176	phnE2	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter permease
HDDNOHNL_00342	3.33e-184	phnE1	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDDNOHNL_00343	2.8e-187	phnX	3.11.1.1	-	E	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the HAD-like hydrolase superfamily. PhnX family
HDDNOHNL_00344	5.35e-270	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HDDNOHNL_00345	4.95e-246	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HDDNOHNL_00346	1.29e-190	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HDDNOHNL_00347	2.64e-213	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HDDNOHNL_00348	8.46e-77	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HDDNOHNL_00349	2.33e-239	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HDDNOHNL_00350	1.39e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HDDNOHNL_00351	1.82e-152	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HDDNOHNL_00352	1.01e-51	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HDDNOHNL_00353	6.22e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HDDNOHNL_00354	8.34e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HDDNOHNL_00355	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDDNOHNL_00356	7.57e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HDDNOHNL_00357	6.7e-141	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HDDNOHNL_00358	8.42e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HDDNOHNL_00359	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDDNOHNL_00360	2.47e-253	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDDNOHNL_00361	2.37e-140	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HDDNOHNL_00362	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HDDNOHNL_00363	4.82e-86	-	-	-	L	-	-	-	nuclease
HDDNOHNL_00364	1.01e-226	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HDDNOHNL_00365	2.76e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HDDNOHNL_00366	3.72e-105	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HDDNOHNL_00367	2.69e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HDDNOHNL_00368	9.76e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HDDNOHNL_00369	2.81e-202	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HDDNOHNL_00370	1.89e-128	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HDDNOHNL_00371	1e-39	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HDDNOHNL_00372	4.55e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HDDNOHNL_00373	1.12e-130	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
HDDNOHNL_00374	1.44e-125	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
HDDNOHNL_00375	1.49e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDDNOHNL_00376	1.35e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HDDNOHNL_00377	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HDDNOHNL_00378	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HDDNOHNL_00379	4.91e-265	yacL	-	-	S	-	-	-	domain protein
HDDNOHNL_00380	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HDDNOHNL_00381	9.43e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HDDNOHNL_00382	5.96e-69	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HDDNOHNL_00383	1.62e-158	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HDDNOHNL_00384	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HDDNOHNL_00385	3.22e-147	zmp2	-	-	O	-	-	-	Zinc-dependent metalloprotease
HDDNOHNL_00386	1.91e-165	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HDDNOHNL_00387	1.22e-226	-	-	-	EG	-	-	-	EamA-like transporter family
HDDNOHNL_00388	3.06e-214	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HDDNOHNL_00389	5.37e-233	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HDDNOHNL_00390	1.05e-172	accA1	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
HDDNOHNL_00391	1.49e-183	accD1	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HDDNOHNL_00392	1.7e-315	accC1	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
HDDNOHNL_00393	9.24e-85	accB1	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin-requiring enzyme
HDDNOHNL_00394	3.15e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HDDNOHNL_00395	4.5e-113	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HDDNOHNL_00396	4.16e-93	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HDDNOHNL_00397	0.0	levR	-	-	K	-	-	-	Sigma-54 interaction domain
HDDNOHNL_00398	9.05e-85	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
HDDNOHNL_00399	4.22e-216	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HDDNOHNL_00400	4.51e-172	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HDDNOHNL_00401	6.46e-218	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HDDNOHNL_00402	1.53e-195	-	-	-	G	-	-	-	Peptidase_C39 like family
HDDNOHNL_00404	1.9e-198	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HDDNOHNL_00405	1.71e-302	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HDDNOHNL_00406	3.09e-106	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HDDNOHNL_00407	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HDDNOHNL_00408	2.57e-94	-	-	-	-	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	-
HDDNOHNL_00409	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HDDNOHNL_00410	1.51e-196	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HDDNOHNL_00411	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HDDNOHNL_00412	5.44e-175	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HDDNOHNL_00413	5.41e-160	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HDDNOHNL_00414	2.92e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HDDNOHNL_00415	2.18e-174	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HDDNOHNL_00416	1.06e-195	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HDDNOHNL_00417	1.59e-247	ysdE	-	-	P	-	-	-	Citrate transporter
HDDNOHNL_00418	3.1e-212	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
HDDNOHNL_00419	1.38e-71	-	-	-	S	-	-	-	Cupin domain
HDDNOHNL_00420	9.02e-66	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
HDDNOHNL_00424	1.75e-193	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HDDNOHNL_00425	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HDDNOHNL_00427	6.04e-217	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HDDNOHNL_00428	3e-127	-	-	-	C	-	-	-	Nitroreductase family
HDDNOHNL_00429	5.02e-228	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HDDNOHNL_00430	3.68e-203	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDDNOHNL_00431	2.2e-157	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HDDNOHNL_00432	1.48e-201	ccpB	-	-	K	-	-	-	lacI family
HDDNOHNL_00433	5.91e-150	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HDDNOHNL_00434	2.48e-227	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HDDNOHNL_00435	8.97e-253	yhhX	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HDDNOHNL_00436	0.0	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HDDNOHNL_00437	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HDDNOHNL_00438	9.38e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
HDDNOHNL_00439	2.66e-172	-	-	-	-	-	-	-	-
HDDNOHNL_00440	1.01e-161	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HDDNOHNL_00441	8.34e-86	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
HDDNOHNL_00442	7.2e-61	-	-	-	S	-	-	-	Enterocin A Immunity
HDDNOHNL_00443	8.94e-221	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HDDNOHNL_00444	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
HDDNOHNL_00445	1.4e-95	-	-	-	K	-	-	-	Transcriptional regulator
HDDNOHNL_00446	1.86e-210	-	-	-	-	-	-	-	-
HDDNOHNL_00447	1.23e-75	-	-	-	-	-	-	-	-
HDDNOHNL_00448	2.8e-63	-	-	-	-	-	-	-	-
HDDNOHNL_00449	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HDDNOHNL_00450	1.83e-37	-	-	-	-	-	-	-	-
HDDNOHNL_00451	1.19e-186	-	-	-	S	ko:K06889	-	ko00000	Dienelactone hydrolase family
HDDNOHNL_00452	9.89e-74	ytpP	-	-	CO	-	-	-	Thioredoxin
HDDNOHNL_00453	3.87e-262	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HDDNOHNL_00454	3.89e-62	-	-	-	-	-	-	-	-
HDDNOHNL_00455	2.57e-70	-	-	-	-	-	-	-	-
HDDNOHNL_00456	6.94e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2798)
HDDNOHNL_00457	1.65e-97	-	-	-	-	-	-	-	-
HDDNOHNL_00458	4.15e-78	-	-	-	-	-	-	-	-
HDDNOHNL_00459	4.26e-250	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HDDNOHNL_00460	0.0	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
HDDNOHNL_00461	2.51e-103	uspA3	-	-	T	-	-	-	universal stress protein
HDDNOHNL_00462	2.5e-203	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HDDNOHNL_00463	4.05e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HDDNOHNL_00464	1.38e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HDDNOHNL_00465	1.25e-283	-	-	-	M	-	-	-	Glycosyl transferases group 1
HDDNOHNL_00466	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HDDNOHNL_00467	2.01e-209	-	-	-	S	-	-	-	Putative esterase
HDDNOHNL_00468	3.53e-169	-	-	-	K	-	-	-	Transcriptional regulator
HDDNOHNL_00469	4.75e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HDDNOHNL_00470	2.48e-178	-	-	-	-	-	-	-	-
HDDNOHNL_00471	1.97e-150	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HDDNOHNL_00472	8.05e-179	rrp8	-	-	K	-	-	-	LytTr DNA-binding domain
HDDNOHNL_00473	1.7e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HDDNOHNL_00474	1.55e-79	-	-	-	-	-	-	-	-
HDDNOHNL_00475	2.61e-96	hsp2	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HDDNOHNL_00476	2.97e-76	-	-	-	-	-	-	-	-
HDDNOHNL_00477	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HDDNOHNL_00478	1.18e-114	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HDDNOHNL_00479	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HDDNOHNL_00480	2.03e-271	yttB	-	-	EGP	-	-	-	Major Facilitator
HDDNOHNL_00481	3.45e-83	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HDDNOHNL_00482	9.75e-39	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HDDNOHNL_00483	4.68e-161	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HDDNOHNL_00484	4.71e-74	-	-	-	S	-	-	-	SdpI/YhfL protein family
HDDNOHNL_00485	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HDDNOHNL_00486	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	Bacterial regulatory proteins, gntR family
HDDNOHNL_00487	1.02e-277	araT2	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HDDNOHNL_00488	1.84e-204	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HDDNOHNL_00489	3.59e-26	-	-	-	-	-	-	-	-
HDDNOHNL_00490	2.09e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HDDNOHNL_00491	6.68e-207	mleR	-	-	K	-	-	-	LysR family
HDDNOHNL_00492	1.29e-148	-	-	-	GM	-	-	-	NAD(P)H-binding
HDDNOHNL_00493	3.86e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HDDNOHNL_00494	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HDDNOHNL_00495	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HDDNOHNL_00496	1.12e-216	oroP	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
HDDNOHNL_00497	5.46e-145	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HDDNOHNL_00498	1.55e-161	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HDDNOHNL_00499	1.04e-218	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HDDNOHNL_00500	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HDDNOHNL_00501	2.76e-271	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HDDNOHNL_00502	1.61e-308	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HDDNOHNL_00503	2.02e-219	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HDDNOHNL_00504	7.13e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HDDNOHNL_00505	0.0	pucR_2	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
HDDNOHNL_00506	3.1e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HDDNOHNL_00507	5.67e-280	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
HDDNOHNL_00508	2.24e-206	-	-	-	GM	-	-	-	NmrA-like family
HDDNOHNL_00509	1.25e-199	-	-	-	T	-	-	-	EAL domain
HDDNOHNL_00510	1.85e-121	-	-	-	-	-	-	-	-
HDDNOHNL_00511	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HDDNOHNL_00512	1.83e-157	-	-	-	E	-	-	-	Methionine synthase
HDDNOHNL_00513	9.06e-279	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HDDNOHNL_00514	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HDDNOHNL_00515	5.35e-133	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HDDNOHNL_00516	4.22e-243	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HDDNOHNL_00517	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HDDNOHNL_00518	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDDNOHNL_00519	6.91e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDDNOHNL_00520	1.17e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDDNOHNL_00521	3.39e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HDDNOHNL_00522	2.87e-270	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HDDNOHNL_00523	3.77e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HDDNOHNL_00524	4.57e-304	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HDDNOHNL_00525	9.92e-143	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HDDNOHNL_00526	5.76e-243	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
HDDNOHNL_00527	4.81e-188	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HDDNOHNL_00528	5.95e-153	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
HDDNOHNL_00529	6.89e-190	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HDDNOHNL_00530	3.7e-233	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HDDNOHNL_00531	2.05e-178	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDDNOHNL_00532	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HDDNOHNL_00533	1.87e-53	-	-	-	-	-	-	-	-
HDDNOHNL_00534	8.2e-81	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HDDNOHNL_00535	7.89e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDDNOHNL_00536	4.21e-175	-	-	-	-	-	-	-	-
HDDNOHNL_00537	1.1e-103	usp5	-	-	T	-	-	-	universal stress protein
HDDNOHNL_00538	3.64e-46	-	-	-	-	-	-	-	-
HDDNOHNL_00539	5.7e-95	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HDDNOHNL_00540	1.76e-114	-	-	-	-	-	-	-	-
HDDNOHNL_00541	5.92e-67	-	-	-	-	-	-	-	-
HDDNOHNL_00542	4.79e-13	-	-	-	-	-	-	-	-
HDDNOHNL_00543	3.03e-299	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HDDNOHNL_00544	1.16e-110	-	-	-	F	-	-	-	belongs to the nudix hydrolase family
HDDNOHNL_00545	1.52e-151	-	-	-	-	-	-	-	-
HDDNOHNL_00546	1.21e-69	-	-	-	-	-	-	-	-
HDDNOHNL_00548	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HDDNOHNL_00549	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HDDNOHNL_00550	4.65e-186	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HDDNOHNL_00551	2.99e-38	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
HDDNOHNL_00552	5.88e-142	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HDDNOHNL_00553	1.13e-132	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HDDNOHNL_00554	2.26e-91	-	-	-	FG	-	-	-	Scavenger mRNA decapping enzyme C-term binding
HDDNOHNL_00555	5.41e-172	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HDDNOHNL_00556	3.25e-48	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
HDDNOHNL_00557	2.45e-269	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HDDNOHNL_00558	4.43e-294	-	-	-	S	-	-	-	Sterol carrier protein domain
HDDNOHNL_00559	7.54e-115	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
HDDNOHNL_00560	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HDDNOHNL_00561	6.09e-152	-	-	-	K	-	-	-	Transcriptional regulator
HDDNOHNL_00562	9.24e-231	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HDDNOHNL_00563	4.29e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HDDNOHNL_00564	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HDDNOHNL_00565	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDDNOHNL_00566	0.0	pbg5	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDDNOHNL_00567	6.7e-74	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
HDDNOHNL_00568	1.86e-64	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HDDNOHNL_00569	1.23e-166	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HDDNOHNL_00570	1.4e-181	epsV	-	-	S	-	-	-	glycosyl transferase family 2
HDDNOHNL_00571	1.75e-156	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
HDDNOHNL_00572	7.63e-107	-	-	-	-	-	-	-	-
HDDNOHNL_00573	5.06e-196	-	-	-	S	-	-	-	hydrolase
HDDNOHNL_00574	6.86e-232	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HDDNOHNL_00575	3.98e-204	-	-	-	EG	-	-	-	EamA-like transporter family
HDDNOHNL_00576	1.96e-224	serA1	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HDDNOHNL_00577	1.54e-131	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HDDNOHNL_00578	0.0	-	-	-	-	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	-
HDDNOHNL_00579	4.75e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HDDNOHNL_00580	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HDDNOHNL_00581	9.78e-187	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HDDNOHNL_00582	0.0	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HDDNOHNL_00583	4.3e-44	-	-	-	-	-	-	-	-
HDDNOHNL_00584	2.38e-164	aroC1	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
HDDNOHNL_00585	0.0	ycaM	-	-	E	-	-	-	amino acid
HDDNOHNL_00586	5.73e-100	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HDDNOHNL_00587	1.66e-211	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
HDDNOHNL_00588	2.43e-206	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HDDNOHNL_00589	2.16e-208	-	-	-	K	-	-	-	Transcriptional regulator
HDDNOHNL_00591	8.59e-85	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HDDNOHNL_00592	1.13e-182	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HDDNOHNL_00593	3.66e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HDDNOHNL_00594	3.3e-202	degV1	-	-	S	-	-	-	DegV family
HDDNOHNL_00595	2.89e-80	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
HDDNOHNL_00596	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HDDNOHNL_00598	2.76e-141	sip3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HDDNOHNL_00599	0.0	-	-	-	-	-	-	-	-
HDDNOHNL_00601	2.13e-209	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HDDNOHNL_00602	2.16e-142	-	-	-	S	-	-	-	Cell surface protein
HDDNOHNL_00603	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HDDNOHNL_00604	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HDDNOHNL_00605	2.14e-155	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HDDNOHNL_00606	3.75e-305	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
HDDNOHNL_00607	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HDDNOHNL_00608	1.55e-158	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HDDNOHNL_00609	3.74e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HDDNOHNL_00610	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HDDNOHNL_00611	8.19e-267	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HDDNOHNL_00612	3.82e-51	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HDDNOHNL_00613	7.24e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HDDNOHNL_00614	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HDDNOHNL_00615	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HDDNOHNL_00616	5.95e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HDDNOHNL_00617	1.59e-95	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HDDNOHNL_00618	2.69e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HDDNOHNL_00619	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HDDNOHNL_00620	3.44e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HDDNOHNL_00621	8.77e-317	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HDDNOHNL_00622	4.96e-289	yttB	-	-	EGP	-	-	-	Major Facilitator
HDDNOHNL_00623	9e-184	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HDDNOHNL_00624	2.19e-290	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HDDNOHNL_00626	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HDDNOHNL_00627	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HDDNOHNL_00628	6.65e-282	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HDDNOHNL_00629	3.49e-269	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HDDNOHNL_00630	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HDDNOHNL_00631	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HDDNOHNL_00632	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HDDNOHNL_00633	8.38e-184	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HDDNOHNL_00634	1.1e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HDDNOHNL_00635	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
HDDNOHNL_00636	3.21e-104	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
HDDNOHNL_00637	4.37e-43	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein domain
HDDNOHNL_00638	2.54e-50	-	-	-	-	-	-	-	-
HDDNOHNL_00640	2.22e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HDDNOHNL_00641	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDDNOHNL_00642	3.55e-313	yycH	-	-	S	-	-	-	YycH protein
HDDNOHNL_00643	3.54e-195	yycI	-	-	S	-	-	-	YycH protein
HDDNOHNL_00644	1.71e-200	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HDDNOHNL_00645	1.5e-253	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HDDNOHNL_00646	6.08e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HDDNOHNL_00647	3.46e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDDNOHNL_00648	0.0	-	-	-	C	-	-	-	Belongs to the aldehyde dehydrogenase family
HDDNOHNL_00649	6.96e-214	-	-	-	L	-	-	-	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HDDNOHNL_00650	5.97e-157	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HDDNOHNL_00651	4.75e-42	pnb	-	-	C	-	-	-	nitroreductase
HDDNOHNL_00652	5.63e-86	pnb	-	-	C	-	-	-	nitroreductase
HDDNOHNL_00653	4.95e-86	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
HDDNOHNL_00654	1.57e-150	-	-	-	S	-	-	-	Elongation factor G-binding protein, N-terminal
HDDNOHNL_00655	0.0	-	-	-	C	-	-	-	FMN_bind
HDDNOHNL_00656	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HDDNOHNL_00657	1.46e-204	-	-	-	K	-	-	-	LysR family
HDDNOHNL_00658	2.49e-95	-	-	-	C	-	-	-	FMN binding
HDDNOHNL_00659	4.48e-98	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HDDNOHNL_00660	4.06e-211	-	-	-	S	-	-	-	KR domain
HDDNOHNL_00661	5.74e-204	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
HDDNOHNL_00662	5.07e-157	ydgI	-	-	C	-	-	-	Nitroreductase family
HDDNOHNL_00663	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HDDNOHNL_00664	1.56e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HDDNOHNL_00665	7.63e-249	pva1	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HDDNOHNL_00666	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HDDNOHNL_00667	6.86e-175	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HDDNOHNL_00668	0.0	hpaH	1.14.14.8, 1.14.14.9	-	Q	ko:K00483,ko:K16901	ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220	ko00000,ko00001,ko01000	4-hydroxyphenylacetate
HDDNOHNL_00669	1.65e-106	-	-	-	S	-	-	-	ASCH
HDDNOHNL_00670	1.25e-164	-	-	-	F	-	-	-	glutamine amidotransferase
HDDNOHNL_00671	1.67e-220	-	-	-	K	-	-	-	WYL domain
HDDNOHNL_00672	1.63e-152	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HDDNOHNL_00673	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HDDNOHNL_00674	7.44e-51	-	-	-	S	-	-	-	Protein of unknown function
HDDNOHNL_00675	2.7e-79	-	-	-	S	-	-	-	Protein of unknown function
HDDNOHNL_00676	8.64e-195	-	-	-	EG	-	-	-	EamA-like transporter family
HDDNOHNL_00677	7.65e-121	yfbM	-	-	K	-	-	-	FR47-like protein
HDDNOHNL_00678	1.4e-162	-	-	-	S	-	-	-	DJ-1/PfpI family
HDDNOHNL_00679	3.14e-230	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HDDNOHNL_00680	1.92e-67	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HDDNOHNL_00681	5.98e-302	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HDDNOHNL_00682	4.77e-215	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HDDNOHNL_00683	7.76e-181	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HDDNOHNL_00684	2.38e-99	-	-	-	-	-	-	-	-
HDDNOHNL_00685	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HDDNOHNL_00686	2.4e-180	-	-	-	-	-	-	-	-
HDDNOHNL_00687	4.07e-05	-	-	-	-	-	-	-	-
HDDNOHNL_00688	5.66e-184	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HDDNOHNL_00689	1.67e-54	-	-	-	-	-	-	-	-
HDDNOHNL_00690	4.29e-166	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDDNOHNL_00691	9.79e-192	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HDDNOHNL_00692	1.84e-235	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
HDDNOHNL_00693	1.15e-155	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
HDDNOHNL_00694	7.9e-306	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
HDDNOHNL_00695	1.78e-160	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
HDDNOHNL_00696	3.58e-174	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HDDNOHNL_00697	1.19e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HDDNOHNL_00698	2.6e-193	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
HDDNOHNL_00699	7.11e-227	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HDDNOHNL_00701	1.87e-175	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HDDNOHNL_00702	7.44e-192	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HDDNOHNL_00703	1.61e-144	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HDDNOHNL_00704	1.45e-261	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HDDNOHNL_00705	2.39e-174	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HDDNOHNL_00706	0.0	-	-	-	L	-	-	-	HIRAN domain
HDDNOHNL_00707	1.24e-109	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HDDNOHNL_00708	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HDDNOHNL_00709	5.18e-159	-	-	-	-	-	-	-	-
HDDNOHNL_00710	2.07e-191	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HDDNOHNL_00711	0.0	pacL1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HDDNOHNL_00712	1.34e-183	-	-	-	F	-	-	-	Phosphorylase superfamily
HDDNOHNL_00713	2.92e-38	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HDDNOHNL_00714	1.72e-142	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HDDNOHNL_00715	1.27e-98	-	-	-	K	-	-	-	Transcriptional regulator
HDDNOHNL_00716	3.99e-96	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HDDNOHNL_00717	5.51e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HDDNOHNL_00718	5.38e-290	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HDDNOHNL_00719	3.98e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HDDNOHNL_00720	2.79e-274	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HDDNOHNL_00722	2.16e-204	morA	-	-	S	-	-	-	reductase
HDDNOHNL_00723	8.21e-213	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo keto reductase
HDDNOHNL_00724	1.92e-106	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase like
HDDNOHNL_00725	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HDDNOHNL_00726	7.45e-103	-	-	-	-	-	-	-	-
HDDNOHNL_00727	0.0	-	-	-	-	-	-	-	-
HDDNOHNL_00728	6.49e-268	-	-	-	C	-	-	-	Oxidoreductase
HDDNOHNL_00729	3.28e-193	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HDDNOHNL_00730	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HDDNOHNL_00731	2.57e-128	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HDDNOHNL_00733	4.37e-167	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HDDNOHNL_00734	4.14e-72	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HDDNOHNL_00735	2.09e-171	-	-	-	-	-	-	-	-
HDDNOHNL_00736	1.57e-191	-	-	-	-	-	-	-	-
HDDNOHNL_00737	3.37e-115	-	-	-	-	-	-	-	-
HDDNOHNL_00738	1.01e-184	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HDDNOHNL_00739	6.03e-218	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HDDNOHNL_00740	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
HDDNOHNL_00741	8.03e-151	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HDDNOHNL_00742	0.0	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
HDDNOHNL_00743	9.67e-98	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HDDNOHNL_00745	5.29e-121	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDDNOHNL_00746	2.35e-243	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
HDDNOHNL_00747	3.05e-236	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
HDDNOHNL_00748	7.88e-131	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
HDDNOHNL_00749	6.76e-75	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
HDDNOHNL_00750	2.32e-171	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HDDNOHNL_00751	2.65e-245	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HDDNOHNL_00752	1.83e-231	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HDDNOHNL_00753	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HDDNOHNL_00754	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HDDNOHNL_00755	2.92e-118	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HDDNOHNL_00756	9.16e-190	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HDDNOHNL_00757	5.09e-81	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
HDDNOHNL_00758	4.61e-222	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDDNOHNL_00759	3.79e-57	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HDDNOHNL_00760	4.85e-119	XK27_09665	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
HDDNOHNL_00761	0.0	-	-	-	M	-	-	-	MucBP domain
HDDNOHNL_00762	5.1e-315	-	-	-	M	-	-	-	MucBP domain
HDDNOHNL_00763	1.42e-08	-	-	-	-	-	-	-	-
HDDNOHNL_00764	1.73e-113	-	-	-	S	-	-	-	AAA domain
HDDNOHNL_00765	8.17e-176	-	-	-	K	-	-	-	sequence-specific DNA binding
HDDNOHNL_00766	2.56e-60	-	-	-	K	-	-	-	Helix-turn-helix domain
HDDNOHNL_00767	7.39e-54	-	-	-	K	-	-	-	Helix-turn-helix domain
HDDNOHNL_00768	3.93e-220	-	-	-	K	-	-	-	Transcriptional regulator
HDDNOHNL_00769	4.37e-120	-	-	-	C	-	-	-	FMN_bind
HDDNOHNL_00770	5.68e-266	-	-	-	C	-	-	-	FMN_bind
HDDNOHNL_00772	4.3e-106	-	-	-	K	-	-	-	Transcriptional regulator
HDDNOHNL_00773	1.64e-149	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HDDNOHNL_00774	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HDDNOHNL_00775	3.39e-255	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HDDNOHNL_00776	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HDDNOHNL_00777	1.32e-290	-	-	-	L	-	-	-	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HDDNOHNL_00778	9.05e-55	-	-	-	-	-	-	-	-
HDDNOHNL_00779	4.95e-44	-	-	-	L	-	-	-	leucine-zipper of insertion element IS481
HDDNOHNL_00780	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HDDNOHNL_00781	9.95e-211	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HDDNOHNL_00782	5.06e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HDDNOHNL_00783	2.91e-179	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HDDNOHNL_00784	2.26e-243	-	-	-	-	-	-	-	-
HDDNOHNL_00785	1.89e-277	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HDDNOHNL_00786	4.18e-163	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HDDNOHNL_00787	7.84e-117	-	-	-	K	-	-	-	FR47-like protein
HDDNOHNL_00788	1.24e-155	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
HDDNOHNL_00789	3.33e-64	-	-	-	-	-	-	-	-
HDDNOHNL_00790	4.24e-246	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HDDNOHNL_00791	0.0	xylP2	-	-	G	-	-	-	symporter
HDDNOHNL_00792	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HDDNOHNL_00793	9.85e-281	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HDDNOHNL_00794	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HDDNOHNL_00795	3.43e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HDDNOHNL_00796	2.03e-155	azlC	-	-	E	-	-	-	branched-chain amino acid
HDDNOHNL_00797	1.75e-47	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HDDNOHNL_00798	1.46e-170	-	-	-	-	-	-	-	-
HDDNOHNL_00799	2.72e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HDDNOHNL_00800	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HDDNOHNL_00801	7.79e-112	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HDDNOHNL_00802	1.36e-77	-	-	-	-	-	-	-	-
HDDNOHNL_00803	2.94e-155	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HDDNOHNL_00804	1.78e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HDDNOHNL_00805	4.6e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
HDDNOHNL_00806	7.76e-100	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HDDNOHNL_00807	2.34e-242	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HDDNOHNL_00808	4.15e-153	-	-	-	I	-	-	-	phosphatase
HDDNOHNL_00809	3.88e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HDDNOHNL_00810	3.03e-129	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HDDNOHNL_00811	5.68e-117	-	-	-	K	-	-	-	Transcriptional regulator
HDDNOHNL_00812	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HDDNOHNL_00813	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HDDNOHNL_00814	7.48e-153	dacB	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HDDNOHNL_00815	1.11e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HDDNOHNL_00816	1.62e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HDDNOHNL_00824	9.78e-102	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HDDNOHNL_00825	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HDDNOHNL_00826	1.16e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDDNOHNL_00827	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDDNOHNL_00828	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDDNOHNL_00829	1.48e-149	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HDDNOHNL_00830	4.19e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HDDNOHNL_00831	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HDDNOHNL_00832	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HDDNOHNL_00833	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HDDNOHNL_00834	1.24e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HDDNOHNL_00835	9.83e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HDDNOHNL_00836	2.27e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HDDNOHNL_00837	6.61e-193	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HDDNOHNL_00838	1.85e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HDDNOHNL_00839	3.59e-69	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HDDNOHNL_00840	5.46e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HDDNOHNL_00841	8.29e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HDDNOHNL_00842	1.11e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HDDNOHNL_00843	1.96e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HDDNOHNL_00844	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HDDNOHNL_00845	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HDDNOHNL_00846	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HDDNOHNL_00847	4.99e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HDDNOHNL_00848	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HDDNOHNL_00849	1.75e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HDDNOHNL_00850	5.32e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HDDNOHNL_00851	8.44e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HDDNOHNL_00852	1.32e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HDDNOHNL_00853	5.95e-300	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HDDNOHNL_00854	1.84e-160	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HDDNOHNL_00855	9.87e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HDDNOHNL_00856	9.65e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HDDNOHNL_00857	7.71e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HDDNOHNL_00858	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDDNOHNL_00859	7.76e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HDDNOHNL_00860	1.02e-233	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HDDNOHNL_00861	1.41e-122	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
HDDNOHNL_00862	4.42e-111	-	-	-	S	-	-	-	NusG domain II
HDDNOHNL_00863	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HDDNOHNL_00864	3.19e-194	-	-	-	S	-	-	-	FMN_bind
HDDNOHNL_00865	3.08e-264	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HDDNOHNL_00866	1.98e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDDNOHNL_00867	2.01e-211	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDDNOHNL_00868	2.29e-182	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDDNOHNL_00869	3.06e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HDDNOHNL_00870	4.58e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HDDNOHNL_00871	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HDDNOHNL_00872	8.51e-210	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HDDNOHNL_00873	1.68e-221	-	-	-	S	-	-	-	Membrane
HDDNOHNL_00874	9.14e-38	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HDDNOHNL_00875	2.99e-208	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HDDNOHNL_00876	0.0	tkt2	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HDDNOHNL_00877	1.65e-211	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HDDNOHNL_00878	3.3e-235	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	DAHP synthetase I family
HDDNOHNL_00879	1.33e-255	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HDDNOHNL_00880	1.49e-281	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HDDNOHNL_00881	1.51e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HDDNOHNL_00882	1.41e-147	-	4.2.1.2, 4.2.1.32	-	C	ko:K01676,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
HDDNOHNL_00883	4.28e-225	ttdA	4.2.1.32	-	C	ko:K03779	ko00630,map00630	ko00000,ko00001,ko01000	Fumarate hydratase (Fumerase)
HDDNOHNL_00884	6.07e-252	-	-	-	K	-	-	-	Helix-turn-helix domain
HDDNOHNL_00885	3.16e-196	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HDDNOHNL_00886	2.04e-170	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HDDNOHNL_00887	1.76e-180	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HDDNOHNL_00888	4.26e-222	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HDDNOHNL_00889	1.18e-66	-	-	-	-	-	-	-	-
HDDNOHNL_00890	9.2e-215	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HDDNOHNL_00891	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HDDNOHNL_00892	8.69e-230	citR	-	-	K	-	-	-	sugar-binding domain protein
HDDNOHNL_00893	1.11e-263	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
HDDNOHNL_00894	3.07e-241	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HDDNOHNL_00895	1.23e-58	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
HDDNOHNL_00896	1.51e-206	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
HDDNOHNL_00897	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
HDDNOHNL_00898	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HDDNOHNL_00899	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HDDNOHNL_00900	2.32e-121	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HDDNOHNL_00901	4.54e-207	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
HDDNOHNL_00902	1.53e-213	mleR	-	-	K	-	-	-	LysR family
HDDNOHNL_00903	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HDDNOHNL_00904	2.6e-212	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
HDDNOHNL_00905	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HDDNOHNL_00906	4.37e-128	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HDDNOHNL_00907	6.07e-33	-	-	-	-	-	-	-	-
HDDNOHNL_00908	0.0	-	-	-	S	ko:K06889	-	ko00000	Alpha beta
HDDNOHNL_00909	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HDDNOHNL_00910	7.76e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HDDNOHNL_00911	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HDDNOHNL_00912	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HDDNOHNL_00913	1.89e-208	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HDDNOHNL_00914	4.87e-234	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HDDNOHNL_00915	4.92e-212	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HDDNOHNL_00916	7.17e-62	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HDDNOHNL_00917	2.15e-07	-	-	-	K	-	-	-	transcriptional regulator
HDDNOHNL_00918	5.58e-274	-	-	-	S	-	-	-	membrane
HDDNOHNL_00919	1.51e-105	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDDNOHNL_00920	0.0	-	-	-	S	-	-	-	Zinc finger, swim domain protein
HDDNOHNL_00921	8.09e-146	-	-	-	GM	-	-	-	epimerase
HDDNOHNL_00922	6.34e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
HDDNOHNL_00923	2.65e-93	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
HDDNOHNL_00924	1.4e-137	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HDDNOHNL_00925	1.68e-176	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HDDNOHNL_00926	0.0	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HDDNOHNL_00927	1.3e-264	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HDDNOHNL_00928	4.38e-102	-	-	-	K	-	-	-	Transcriptional regulator
HDDNOHNL_00929	4.6e-307	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
HDDNOHNL_00930	1.27e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HDDNOHNL_00931	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HDDNOHNL_00932	1.68e-229	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HDDNOHNL_00933	4.8e-278	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HDDNOHNL_00934	1.93e-266	-	-	-	-	-	-	-	-
HDDNOHNL_00935	6.11e-118	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDDNOHNL_00936	2.65e-81	-	-	-	P	-	-	-	Rhodanese Homology Domain
HDDNOHNL_00937	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HDDNOHNL_00938	2.74e-112	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDDNOHNL_00939	2.08e-213	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HDDNOHNL_00940	2.52e-165	drrB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HDDNOHNL_00941	1.75e-295	-	-	-	M	-	-	-	O-Antigen ligase
HDDNOHNL_00942	6.85e-164	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HDDNOHNL_00943	1.09e-249	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HDDNOHNL_00944	1.29e-298	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HDDNOHNL_00945	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HDDNOHNL_00947	7.03e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HDDNOHNL_00948	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HDDNOHNL_00949	8.69e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HDDNOHNL_00950	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HDDNOHNL_00951	2.51e-98	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
HDDNOHNL_00952	4.59e-217	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HDDNOHNL_00953	3.13e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HDDNOHNL_00954	3.99e-92	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDDNOHNL_00955	7.1e-176	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HDDNOHNL_00956	1.3e-132	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HDDNOHNL_00957	2.69e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HDDNOHNL_00958	2.24e-126	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HDDNOHNL_00959	3.38e-252	-	-	-	S	-	-	-	Helix-turn-helix domain
HDDNOHNL_00960	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HDDNOHNL_00961	1.25e-39	-	-	-	M	-	-	-	Lysin motif
HDDNOHNL_00962	1.27e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HDDNOHNL_00963	1.98e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HDDNOHNL_00964	5.89e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HDDNOHNL_00965	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HDDNOHNL_00966	2.08e-284	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HDDNOHNL_00967	1.29e-192	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HDDNOHNL_00968	1.39e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HDDNOHNL_00969	6.04e-290	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HDDNOHNL_00970	6.46e-109	-	-	-	-	-	-	-	-
HDDNOHNL_00971	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HDDNOHNL_00972	6.7e-241	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HDDNOHNL_00973	1.8e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HDDNOHNL_00974	2.03e-189	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HDDNOHNL_00975	1.19e-208	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HDDNOHNL_00976	3.29e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HDDNOHNL_00977	9.33e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HDDNOHNL_00978	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HDDNOHNL_00979	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HDDNOHNL_00980	4.28e-253	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HDDNOHNL_00981	3.53e-160	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HDDNOHNL_00982	1.27e-222	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
HDDNOHNL_00983	1.73e-219	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
HDDNOHNL_00984	5.99e-291	XK27_05470	-	-	E	-	-	-	Methionine synthase
HDDNOHNL_00986	2.25e-207	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HDDNOHNL_00987	8.64e-177	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDDNOHNL_00988	2.33e-202	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HDDNOHNL_00989	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HDDNOHNL_00990	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HDDNOHNL_00991	1.5e-227	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HDDNOHNL_00992	6.84e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HDDNOHNL_00993	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HDDNOHNL_00994	3.64e-217	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HDDNOHNL_00995	2.4e-137	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HDDNOHNL_00996	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HDDNOHNL_00997	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HDDNOHNL_00998	2.21e-227	-	-	-	K	-	-	-	Transcriptional regulator
HDDNOHNL_00999	3.21e-215	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HDDNOHNL_01000	3.8e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HDDNOHNL_01001	9.17e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HDDNOHNL_01002	1.07e-43	-	-	-	S	-	-	-	YozE SAM-like fold
HDDNOHNL_01003	3.59e-204	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HDDNOHNL_01004	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HDDNOHNL_01005	4.49e-315	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HDDNOHNL_01006	3.22e-87	-	-	-	-	-	-	-	-
HDDNOHNL_01007	0.0	gshR1	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HDDNOHNL_01008	1.48e-98	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDDNOHNL_01009	4.87e-123	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HDDNOHNL_01010	0.0	tarL	2.7.8.14, 2.7.8.47	-	H	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HDDNOHNL_01011	1.43e-273	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	H	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HDDNOHNL_01012	6.51e-247	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HDDNOHNL_01013	2.13e-151	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HDDNOHNL_01014	4.76e-290	-	-	-	-	-	-	-	-
HDDNOHNL_01015	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HDDNOHNL_01016	7.79e-78	-	-	-	-	-	-	-	-
HDDNOHNL_01017	2.79e-181	-	-	-	-	-	-	-	-
HDDNOHNL_01018	1.06e-312	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HDDNOHNL_01019	1.05e-176	XK27_00890	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
HDDNOHNL_01020	9.3e-167	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
HDDNOHNL_01021	1.33e-67	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
HDDNOHNL_01023	6e-268	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
HDDNOHNL_01024	4.87e-191	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HDDNOHNL_01025	2.37e-65	-	-	-	-	-	-	-	-
HDDNOHNL_01026	1.27e-35	-	-	-	-	-	-	-	-
HDDNOHNL_01027	1.96e-168	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HDDNOHNL_01028	2.47e-101	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
HDDNOHNL_01029	4.53e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
HDDNOHNL_01030	1.97e-87	-	-	-	K	-	-	-	Transcriptional regulator
HDDNOHNL_01031	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HDDNOHNL_01032	1.6e-171	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HDDNOHNL_01033	2.16e-208	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDDNOHNL_01034	1.37e-119	-	-	-	F	-	-	-	NUDIX domain
HDDNOHNL_01035	1.19e-176	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
HDDNOHNL_01036	2.08e-92	-	-	-	S	-	-	-	LuxR family transcriptional regulator
HDDNOHNL_01037	1.92e-168	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
HDDNOHNL_01040	1.9e-93	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HDDNOHNL_01041	3.34e-144	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HDDNOHNL_01042	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HDDNOHNL_01043	4.89e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HDDNOHNL_01044	1.9e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HDDNOHNL_01045	9.72e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HDDNOHNL_01046	1.65e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HDDNOHNL_01047	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HDDNOHNL_01048	5.89e-81	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HDDNOHNL_01049	3.28e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HDDNOHNL_01050	2.44e-267	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
HDDNOHNL_01051	2.13e-186	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
HDDNOHNL_01052	2.27e-247	-	-	-	-	-	-	-	-
HDDNOHNL_01053	1.9e-156	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HDDNOHNL_01054	4.35e-159	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HDDNOHNL_01055	1.38e-232	-	-	-	V	-	-	-	LD-carboxypeptidase
HDDNOHNL_01056	1.23e-311	-	-	-	M	ko:K07273	-	ko00000	hydrolase, family 25
HDDNOHNL_01057	1.01e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HDDNOHNL_01058	4.82e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HDDNOHNL_01059	1.81e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDDNOHNL_01060	5.41e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HDDNOHNL_01061	2.03e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDDNOHNL_01062	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HDDNOHNL_01063	9.14e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HDDNOHNL_01064	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HDDNOHNL_01065	5.95e-74	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HDDNOHNL_01066	4.85e-314	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HDDNOHNL_01067	1.68e-132	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HDDNOHNL_01068	1.44e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HDDNOHNL_01069	1.52e-57	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HDDNOHNL_01070	1.04e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HDDNOHNL_01071	2.15e-280	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HDDNOHNL_01072	3.2e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
HDDNOHNL_01073	2.24e-239	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HDDNOHNL_01074	2.1e-151	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDDNOHNL_01075	8.69e-191	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HDDNOHNL_01076	3.34e-215	hicD3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HDDNOHNL_01077	3.26e-227	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HDDNOHNL_01078	7.55e-242	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HDDNOHNL_01079	6.54e-273	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HDDNOHNL_01080	0.0	glpQ3	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HDDNOHNL_01081	4.7e-207	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HDDNOHNL_01082	1.1e-258	bla2	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HDDNOHNL_01083	2.37e-107	uspA	-	-	T	-	-	-	universal stress protein
HDDNOHNL_01084	1.34e-52	-	-	-	-	-	-	-	-
HDDNOHNL_01085	7.27e-303	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HDDNOHNL_01086	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HDDNOHNL_01087	9.17e-59	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HDDNOHNL_01088	1.24e-139	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HDDNOHNL_01089	1.63e-104	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HDDNOHNL_01090	4.02e-145	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HDDNOHNL_01091	2.15e-137	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HDDNOHNL_01092	7.5e-105	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HDDNOHNL_01093	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HDDNOHNL_01094	2.59e-277	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HDDNOHNL_01095	8.93e-291	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HDDNOHNL_01096	1.57e-299	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
HDDNOHNL_01097	3.56e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HDDNOHNL_01098	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HDDNOHNL_01099	4.91e-313	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HDDNOHNL_01100	1.15e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HDDNOHNL_01101	1.74e-211	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HDDNOHNL_01102	3.76e-184	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HDDNOHNL_01103	9.47e-115	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HDDNOHNL_01104	3.81e-150	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HDDNOHNL_01105	1.23e-187	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HDDNOHNL_01106	1.89e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HDDNOHNL_01107	3.17e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HDDNOHNL_01108	2.61e-199	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HDDNOHNL_01109	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HDDNOHNL_01110	3.55e-296	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HDDNOHNL_01111	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
HDDNOHNL_01112	5.74e-172	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HDDNOHNL_01113	1.92e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HDDNOHNL_01114	3.83e-295	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HDDNOHNL_01115	2.43e-264	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HDDNOHNL_01116	6.57e-291	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HDDNOHNL_01117	6.18e-197	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
HDDNOHNL_01118	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HDDNOHNL_01119	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HDDNOHNL_01120	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
HDDNOHNL_01121	1.3e-91	-	-	-	-	-	-	-	-
HDDNOHNL_01122	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HDDNOHNL_01123	4.02e-114	-	-	-	-	-	-	-	-
HDDNOHNL_01124	2.83e-138	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HDDNOHNL_01125	2.62e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HDDNOHNL_01126	5.87e-256	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HDDNOHNL_01127	9.91e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HDDNOHNL_01128	1.32e-63	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HDDNOHNL_01129	2.48e-276	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HDDNOHNL_01130	8.32e-227	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HDDNOHNL_01131	2.79e-316	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HDDNOHNL_01132	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HDDNOHNL_01133	5e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HDDNOHNL_01134	5.39e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HDDNOHNL_01135	1.31e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HDDNOHNL_01136	1.06e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HDDNOHNL_01137	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HDDNOHNL_01138	3e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HDDNOHNL_01139	1.45e-161	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HDDNOHNL_01140	5.06e-194	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HDDNOHNL_01141	8.49e-144	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HDDNOHNL_01142	4.03e-125	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HDDNOHNL_01143	7.94e-114	ykuL	-	-	S	-	-	-	(CBS) domain
HDDNOHNL_01144	2.29e-112	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HDDNOHNL_01145	6.72e-289	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HDDNOHNL_01146	2.31e-202	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HDDNOHNL_01147	1.88e-75	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HDDNOHNL_01148	1.6e-96	-	-	-	-	-	-	-	-
HDDNOHNL_01149	9.86e-82	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HDDNOHNL_01150	7.36e-274	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HDDNOHNL_01151	5.44e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HDDNOHNL_01152	3.21e-210	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HDDNOHNL_01153	2.44e-65	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
HDDNOHNL_01154	2.21e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HDDNOHNL_01155	2.06e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HDDNOHNL_01156	2.57e-224	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HDDNOHNL_01157	6.2e-242	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HDDNOHNL_01158	1.97e-72	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HDDNOHNL_01159	1.5e-108	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
HDDNOHNL_01160	3.03e-27	-	-	-	-	ko:K02671	-	ko00000,ko02035,ko02044	-
HDDNOHNL_01161	6.46e-113	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
HDDNOHNL_01163	3.68e-235	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HDDNOHNL_01164	4.7e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDDNOHNL_01165	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HDDNOHNL_01166	5.77e-151	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HDDNOHNL_01167	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HDDNOHNL_01168	1.96e-116	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HDDNOHNL_01169	7.18e-189	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HDDNOHNL_01170	2.71e-150	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HDDNOHNL_01171	8.38e-152	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HDDNOHNL_01172	5.16e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HDDNOHNL_01173	2e-98	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	general stress protein
HDDNOHNL_01175	1.96e-293	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Cell cycle protein
HDDNOHNL_01176	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDDNOHNL_01177	3.82e-184	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HDDNOHNL_01178	4.46e-281	ywtF_2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HDDNOHNL_01179	2.19e-131	-	-	-	L	-	-	-	Helix-turn-helix domain
HDDNOHNL_01180	1.14e-226	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family 2
HDDNOHNL_01181	3.81e-87	-	-	-	-	-	-	-	-
HDDNOHNL_01182	1.38e-98	-	-	-	-	-	-	-	-
HDDNOHNL_01183	1.56e-276	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HDDNOHNL_01184	7.8e-123	-	-	-	-	-	-	-	-
HDDNOHNL_01185	7.22e-149	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HDDNOHNL_01186	7.68e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
HDDNOHNL_01187	3.96e-44	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HDDNOHNL_01188	8.8e-155	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HDDNOHNL_01189	2.11e-171	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HDDNOHNL_01190	5.67e-64	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HDDNOHNL_01191	1.92e-239	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDDNOHNL_01192	2.92e-172	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
HDDNOHNL_01193	6.33e-185	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HDDNOHNL_01194	1.88e-194	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HDDNOHNL_01195	3.01e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HDDNOHNL_01196	9.83e-113	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HDDNOHNL_01197	3.17e-190	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HDDNOHNL_01198	1.13e-175	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HDDNOHNL_01199	4.64e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HDDNOHNL_01200	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HDDNOHNL_01201	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDDNOHNL_01202	9.74e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HDDNOHNL_01203	4.46e-275	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HDDNOHNL_01204	2.95e-65	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HDDNOHNL_01205	3.28e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
HDDNOHNL_01206	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HDDNOHNL_01207	3.04e-71	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HDDNOHNL_01208	0.0	-	-	-	G	-	-	-	Major Facilitator
HDDNOHNL_01209	3.67e-275	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HDDNOHNL_01210	1.63e-121	-	-	-	-	-	-	-	-
HDDNOHNL_01211	1.19e-285	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HDDNOHNL_01212	1.21e-245	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HDDNOHNL_01213	2.41e-113	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HDDNOHNL_01214	8.94e-221	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HDDNOHNL_01215	2.53e-240	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HDDNOHNL_01216	1.19e-169	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HDDNOHNL_01217	4.42e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HDDNOHNL_01218	1.28e-106	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HDDNOHNL_01219	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HDDNOHNL_01220	2.54e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HDDNOHNL_01221	8.49e-266	pbpX2	-	-	V	-	-	-	Beta-lactamase
HDDNOHNL_01222	8.59e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HDDNOHNL_01223	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDDNOHNL_01224	3.27e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HDDNOHNL_01225	5.75e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDDNOHNL_01226	1.68e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HDDNOHNL_01227	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HDDNOHNL_01228	1.01e-158	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDDNOHNL_01231	1.73e-67	-	-	-	-	-	-	-	-
HDDNOHNL_01232	4.78e-65	-	-	-	-	-	-	-	-
HDDNOHNL_01233	5.28e-146	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HDDNOHNL_01234	2.04e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HDDNOHNL_01235	3.13e-172	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HDDNOHNL_01236	2.56e-76	-	-	-	-	-	-	-	-
HDDNOHNL_01237	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HDDNOHNL_01238	8.2e-102	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HDDNOHNL_01239	2.43e-150	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
HDDNOHNL_01240	2.29e-207	-	-	-	G	-	-	-	Fructosamine kinase
HDDNOHNL_01241	4.01e-200	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
HDDNOHNL_01242	2.47e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HDDNOHNL_01243	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HDDNOHNL_01244	2.61e-132	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HDDNOHNL_01245	4.35e-204	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HDDNOHNL_01246	1.84e-284	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HDDNOHNL_01247	1.42e-217	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HDDNOHNL_01248	1.78e-140	-	-	-	C	-	-	-	Enoyl-(Acyl carrier protein) reductase
HDDNOHNL_01249	2.32e-194	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HDDNOHNL_01250	1.09e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HDDNOHNL_01251	9.21e-94	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HDDNOHNL_01252	4.81e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HDDNOHNL_01253	3.14e-109	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HDDNOHNL_01254	1.15e-94	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HDDNOHNL_01255	7.92e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HDDNOHNL_01256	2.84e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HDDNOHNL_01257	8.64e-224	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HDDNOHNL_01258	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HDDNOHNL_01259	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HDDNOHNL_01260	1.74e-251	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HDDNOHNL_01261	1.18e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HDDNOHNL_01262	4.94e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDDNOHNL_01263	5.23e-256	-	-	-	-	-	-	-	-
HDDNOHNL_01264	1.43e-251	-	-	-	-	-	-	-	-
HDDNOHNL_01265	6.05e-170	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HDDNOHNL_01266	1.03e-206	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDDNOHNL_01267	0.000138	yjdF	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HDDNOHNL_01268	1.49e-147	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDDNOHNL_01269	2.25e-93	-	-	-	K	-	-	-	MarR family
HDDNOHNL_01270	6.64e-109	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HDDNOHNL_01272	4.17e-204	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HDDNOHNL_01273	1.27e-174	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HDDNOHNL_01274	5.11e-266	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDDNOHNL_01275	1.51e-132	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
HDDNOHNL_01276	0.0	nox4	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HDDNOHNL_01278	3.78e-221	cryZ	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HDDNOHNL_01279	5.72e-207	-	-	-	K	-	-	-	Transcriptional regulator
HDDNOHNL_01280	1.74e-101	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
HDDNOHNL_01281	1.39e-143	-	-	-	GM	-	-	-	NmrA-like family
HDDNOHNL_01282	8.81e-205	-	-	-	S	-	-	-	Alpha beta hydrolase
HDDNOHNL_01283	2.49e-167	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HDDNOHNL_01284	2.31e-132	thgA3	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HDDNOHNL_01285	7.21e-145	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
HDDNOHNL_01286	6.43e-263	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HDDNOHNL_01287	2.91e-29	-	-	-	-	-	-	-	-
HDDNOHNL_01288	1.93e-102	-	-	-	-	-	-	-	-
HDDNOHNL_01292	0.0	-	-	-	S	-	-	-	Phage minor structural protein
HDDNOHNL_01293	0.0	-	-	-	S	-	-	-	Phage tail protein
HDDNOHNL_01294	0.0	-	-	-	D	-	-	-	domain protein
HDDNOHNL_01295	6.36e-34	-	-	-	-	-	-	-	-
HDDNOHNL_01296	1.35e-75	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
HDDNOHNL_01297	2.16e-131	-	-	-	S	-	-	-	Phage tail tube protein
HDDNOHNL_01298	7.47e-74	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
HDDNOHNL_01299	2.25e-86	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HDDNOHNL_01300	3.45e-76	-	-	-	S	-	-	-	Phage head-tail joining protein
HDDNOHNL_01301	9.36e-65	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HDDNOHNL_01302	1.03e-254	-	-	-	S	-	-	-	Phage capsid family
HDDNOHNL_01303	5.99e-164	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HDDNOHNL_01304	6.97e-284	-	-	-	S	-	-	-	Phage portal protein
HDDNOHNL_01305	6.68e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF1056)
HDDNOHNL_01306	0.0	-	-	-	S	-	-	-	Phage Terminase
HDDNOHNL_01307	6.68e-103	-	-	-	L	-	-	-	Phage terminase, small subunit
HDDNOHNL_01309	7.81e-113	-	-	-	L	-	-	-	HNH nucleases
HDDNOHNL_01310	1.26e-12	-	-	-	-	-	-	-	-
HDDNOHNL_01311	1.13e-84	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
HDDNOHNL_01312	2.2e-23	-	-	-	-	-	-	-	-
HDDNOHNL_01313	5.27e-72	-	-	-	-	-	-	-	-
HDDNOHNL_01314	1.28e-09	-	-	-	S	-	-	-	YopX protein
HDDNOHNL_01316	8.89e-118	-	-	-	L	-	-	-	C-5 cytosine-specific DNA methylase
HDDNOHNL_01318	2.95e-06	-	-	-	-	-	-	-	-
HDDNOHNL_01319	4.01e-87	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HDDNOHNL_01320	3.77e-76	-	-	-	-	-	-	-	-
HDDNOHNL_01322	2.84e-169	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
HDDNOHNL_01323	6.11e-56	-	-	-	L	-	-	-	DnaD domain protein
HDDNOHNL_01324	2.93e-167	-	-	-	S	-	-	-	Putative HNHc nuclease
HDDNOHNL_01325	3.13e-127	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
HDDNOHNL_01326	3.98e-151	-	-	-	S	-	-	-	AAA domain
HDDNOHNL_01327	4.24e-188	-	-	-	S	-	-	-	Protein of unknown function (DUF1351)
HDDNOHNL_01329	2e-25	-	-	-	-	-	-	-	-
HDDNOHNL_01335	7.34e-80	-	-	-	S	-	-	-	DNA binding
HDDNOHNL_01338	1.56e-27	-	-	-	-	-	-	-	-
HDDNOHNL_01339	2.59e-99	-	-	-	K	-	-	-	Peptidase S24-like
HDDNOHNL_01346	6.15e-75	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDDNOHNL_01347	5.03e-43	-	-	-	-	-	-	-	-
HDDNOHNL_01348	2.21e-178	-	-	-	Q	-	-	-	Methyltransferase
HDDNOHNL_01349	2.84e-75	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
HDDNOHNL_01350	1.66e-269	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HDDNOHNL_01351	3.58e-129	-	-	-	K	-	-	-	Helix-turn-helix domain
HDDNOHNL_01352	1.52e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HDDNOHNL_01353	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HDDNOHNL_01354	1.84e-67	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HDDNOHNL_01355	7.09e-180	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDDNOHNL_01356	8.34e-228	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HDDNOHNL_01357	6.62e-62	-	-	-	-	-	-	-	-
HDDNOHNL_01358	1.55e-311	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HDDNOHNL_01359	3.02e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HDDNOHNL_01360	4.24e-218	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HDDNOHNL_01361	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HDDNOHNL_01362	0.0	-	3.1.4.53	-	S	ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HDDNOHNL_01363	0.0	cps4J	-	-	S	-	-	-	MatE
HDDNOHNL_01364	4.82e-228	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
HDDNOHNL_01365	1.91e-297	-	-	-	-	-	-	-	-
HDDNOHNL_01366	7.88e-48	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
HDDNOHNL_01367	1.82e-132	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
HDDNOHNL_01368	1.43e-223	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
HDDNOHNL_01369	3.18e-162	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
HDDNOHNL_01370	8.71e-231	cps4D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HDDNOHNL_01371	5.54e-189	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HDDNOHNL_01372	2.02e-156	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HDDNOHNL_01373	8.45e-162	epsB	-	-	M	-	-	-	biosynthesis protein
HDDNOHNL_01374	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HDDNOHNL_01375	3.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HDDNOHNL_01376	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HDDNOHNL_01377	5.12e-31	-	-	-	-	-	-	-	-
HDDNOHNL_01378	6.47e-95	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HDDNOHNL_01379	1.3e-65	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HDDNOHNL_01380	9.6e-143	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HDDNOHNL_01381	7.8e-300	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HDDNOHNL_01382	3.21e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HDDNOHNL_01383	4.38e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HDDNOHNL_01384	9.34e-201	-	-	-	S	-	-	-	Tetratricopeptide repeat
HDDNOHNL_01385	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HDDNOHNL_01386	1.29e-200	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HDDNOHNL_01387	1.8e-135	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HDDNOHNL_01388	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HDDNOHNL_01389	1.18e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HDDNOHNL_01390	8.43e-240	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HDDNOHNL_01391	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HDDNOHNL_01392	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HDDNOHNL_01393	2.1e-161	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HDDNOHNL_01394	1.05e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HDDNOHNL_01395	7.04e-108	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HDDNOHNL_01396	8.61e-132	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HDDNOHNL_01397	1.91e-66	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HDDNOHNL_01398	5.88e-170	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HDDNOHNL_01399	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HDDNOHNL_01400	1.45e-260	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HDDNOHNL_01401	0.0	-	-	-	-	-	-	-	-
HDDNOHNL_01402	1.56e-262	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
HDDNOHNL_01403	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HDDNOHNL_01404	2.1e-33	-	-	-	-	-	-	-	-
HDDNOHNL_01405	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDDNOHNL_01406	1.89e-254	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HDDNOHNL_01407	2.62e-76	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HDDNOHNL_01408	0.0	-	3.6.3.44	-	P	ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
HDDNOHNL_01409	4.63e-24	-	-	-	-	-	-	-	-
HDDNOHNL_01410	1.25e-25	-	-	-	-	-	-	-	-
HDDNOHNL_01411	9.85e-22	-	-	-	-	-	-	-	-
HDDNOHNL_01412	2.69e-23	-	-	-	-	-	-	-	-
HDDNOHNL_01413	9.05e-22	-	-	-	-	-	-	-	-
HDDNOHNL_01414	1.63e-104	inlJ	-	-	M	-	-	-	MucBP domain
HDDNOHNL_01415	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
HDDNOHNL_01416	1.27e-109	-	-	-	K	-	-	-	MarR family
HDDNOHNL_01417	9.28e-58	-	-	-	-	-	-	-	-
HDDNOHNL_01418	1.28e-51	-	-	-	-	-	-	-	-
HDDNOHNL_01419	1.79e-289	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDDNOHNL_01420	1.1e-06	-	-	-	K	ko:K07727	-	ko00000,ko03000	transcriptional regulator
HDDNOHNL_01423	2.62e-40	-	-	-	-	-	-	-	-
HDDNOHNL_01424	1.5e-187	-	-	-	L	-	-	-	DNA replication protein
HDDNOHNL_01425	0.0	-	-	-	S	-	-	-	Virulence-associated protein E
HDDNOHNL_01426	3.36e-96	-	-	-	-	-	-	-	-
HDDNOHNL_01428	3.24e-62	-	-	-	S	-	-	-	Head-tail joining protein
HDDNOHNL_01429	1.05e-88	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	Phage-associated protein
HDDNOHNL_01430	1.9e-109	terS	-	-	L	-	-	-	Phage terminase, small subunit
HDDNOHNL_01431	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
HDDNOHNL_01433	6.16e-260	-	-	-	S	-	-	-	Phage portal protein
HDDNOHNL_01434	0.0	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
HDDNOHNL_01435	1.75e-48	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HDDNOHNL_01436	1.02e-80	-	-	-	-	-	-	-	-
HDDNOHNL_01439	1.98e-40	-	-	-	-	-	-	-	-
HDDNOHNL_01441	9.38e-279	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDDNOHNL_01445	4.23e-19	-	-	-	S	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HDDNOHNL_01447	2.69e-38	-	-	-	S	-	-	-	TerB N-terminal domain
HDDNOHNL_01448	1.92e-97	-	-	-	E	-	-	-	IrrE N-terminal-like domain
HDDNOHNL_01449	2.67e-80	-	-	-	K	-	-	-	Helix-turn-helix domain
HDDNOHNL_01450	7.19e-51	-	-	-	K	-	-	-	Helix-turn-helix
HDDNOHNL_01452	6.59e-72	-	-	-	-	-	-	-	-
HDDNOHNL_01453	2.15e-110	-	-	-	-	-	-	-	-
HDDNOHNL_01455	8e-70	-	-	-	S	-	-	-	Bacteriophage Mu Gam like protein
HDDNOHNL_01456	6.45e-80	-	-	-	-	-	-	-	-
HDDNOHNL_01457	7.28e-213	-	-	-	L	-	-	-	DnaD domain protein
HDDNOHNL_01458	3.24e-67	-	-	-	-	-	-	-	-
HDDNOHNL_01459	1.19e-108	-	-	-	-	-	-	-	-
HDDNOHNL_01460	1.91e-85	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HDDNOHNL_01462	3.54e-18	-	-	-	S	-	-	-	YopX protein
HDDNOHNL_01467	2.49e-97	-	-	-	K	-	-	-	acetyltransferase
HDDNOHNL_01468	1.15e-40	-	-	-	S	-	-	-	ASCH
HDDNOHNL_01469	7.56e-25	-	-	-	-	-	-	-	-
HDDNOHNL_01472	3.13e-98	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
HDDNOHNL_01474	2.91e-316	-	-	-	S	ko:K06909	-	ko00000	Phage terminase, large subunit
HDDNOHNL_01475	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HDDNOHNL_01476	5.76e-216	-	-	-	S	-	-	-	Phage Mu protein F like protein
HDDNOHNL_01477	2.66e-110	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
HDDNOHNL_01478	2.45e-247	gpG	-	-	-	-	-	-	-
HDDNOHNL_01479	3.11e-75	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HDDNOHNL_01480	5.46e-67	-	-	-	-	-	-	-	-
HDDNOHNL_01481	9.66e-123	-	-	-	-	-	-	-	-
HDDNOHNL_01482	5.59e-81	-	-	-	-	-	-	-	-
HDDNOHNL_01483	2.09e-123	-	-	-	-	-	-	-	-
HDDNOHNL_01484	5.37e-107	-	-	-	S	-	-	-	Phage tail assembly chaperone protein, TAC
HDDNOHNL_01486	0.0	-	-	-	D	-	-	-	domain protein
HDDNOHNL_01487	9.72e-173	-	-	-	S	-	-	-	phage tail
HDDNOHNL_01488	0.0	-	-	-	M	-	-	-	Prophage endopeptidase tail
HDDNOHNL_01489	2.64e-220	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HDDNOHNL_01490	8.28e-127	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
HDDNOHNL_01494	1.4e-108	-	-	-	-	-	-	-	-
HDDNOHNL_01495	1.4e-27	-	-	-	-	-	-	-	-
HDDNOHNL_01497	1.7e-255	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HDDNOHNL_01498	2.53e-47	-	-	-	S	-	-	-	Haemolysin XhlA
HDDNOHNL_01499	5.11e-59	-	-	-	S	-	-	-	Bacteriophage holin
HDDNOHNL_01500	2.93e-73	-	-	-	V	-	-	-	Abortive infection bacteriophage resistance protein
HDDNOHNL_01501	2.91e-177	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
HDDNOHNL_01502	1.81e-85	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HDDNOHNL_01503	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HDDNOHNL_01504	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HDDNOHNL_01505	1.08e-181	-	-	-	-	-	-	-	-
HDDNOHNL_01506	1.33e-77	-	-	-	-	-	-	-	-
HDDNOHNL_01507	1.9e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HDDNOHNL_01508	8.57e-41	-	-	-	-	-	-	-	-
HDDNOHNL_01509	3.76e-245	ampC	-	-	V	-	-	-	Beta-lactamase
HDDNOHNL_01510	4.07e-249	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HDDNOHNL_01511	3.04e-174	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HDDNOHNL_01512	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
HDDNOHNL_01513	1.54e-141	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HDDNOHNL_01514	1.88e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HDDNOHNL_01515	3.44e-204	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HDDNOHNL_01516	1.79e-243	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HDDNOHNL_01517	3.04e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HDDNOHNL_01518	7.81e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HDDNOHNL_01519	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HDDNOHNL_01520	1.56e-46	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HDDNOHNL_01521	3.91e-289	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HDDNOHNL_01522	2.29e-292	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HDDNOHNL_01523	2.16e-241	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HDDNOHNL_01524	2.04e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HDDNOHNL_01525	1.41e-285	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HDDNOHNL_01526	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HDDNOHNL_01527	1.24e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HDDNOHNL_01528	5.6e-41	-	-	-	-	-	-	-	-
HDDNOHNL_01529	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HDDNOHNL_01530	3.29e-95	-	-	-	L	-	-	-	Integrase
HDDNOHNL_01531	3.4e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HDDNOHNL_01532	5.67e-231	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HDDNOHNL_01533	4.86e-258	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HDDNOHNL_01534	3.59e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDDNOHNL_01535	3.44e-210	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDDNOHNL_01536	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HDDNOHNL_01537	3.85e-76	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
HDDNOHNL_01538	1.01e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HDDNOHNL_01539	1.36e-208	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HDDNOHNL_01540	1.01e-250	-	-	-	M	-	-	-	MucBP domain
HDDNOHNL_01541	0.0	-	-	-	-	-	-	-	-
HDDNOHNL_01542	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HDDNOHNL_01543	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HDDNOHNL_01544	1.22e-218	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HDDNOHNL_01545	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HDDNOHNL_01546	7.89e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HDDNOHNL_01547	6.04e-94	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HDDNOHNL_01548	1.13e-257	yueF	-	-	S	-	-	-	AI-2E family transporter
HDDNOHNL_01549	7.3e-216	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HDDNOHNL_01550	7.17e-39	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HDDNOHNL_01551	3.97e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
HDDNOHNL_01552	1.94e-170	lytE	-	-	M	-	-	-	NlpC/P60 family
HDDNOHNL_01553	6.62e-138	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HDDNOHNL_01554	1.01e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HDDNOHNL_01555	1.34e-168	-	-	-	-	-	-	-	-
HDDNOHNL_01556	1.68e-131	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HDDNOHNL_01557	3.31e-35	-	-	-	-	-	-	-	-
HDDNOHNL_01558	1.95e-41	-	-	-	-	-	-	-	-
HDDNOHNL_01559	1.04e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HDDNOHNL_01560	9.02e-70	-	-	-	-	-	-	-	-
HDDNOHNL_01562	3.98e-169	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HDDNOHNL_01563	1.95e-197	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HDDNOHNL_01564	3.34e-267	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HDDNOHNL_01565	3.3e-281	pbpX	-	-	V	-	-	-	Beta-lactamase
HDDNOHNL_01566	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HDDNOHNL_01567	8.31e-139	-	-	-	-	-	-	-	-
HDDNOHNL_01568	7.62e-97	-	-	-	-	-	-	-	-
HDDNOHNL_01570	3.21e-209	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HDDNOHNL_01571	3.15e-313	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDDNOHNL_01572	3.93e-99	-	-	-	T	-	-	-	Universal stress protein family
HDDNOHNL_01574	5.62e-316	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HDDNOHNL_01575	7.89e-245	mocA	-	-	S	-	-	-	Oxidoreductase
HDDNOHNL_01576	6.22e-43	cspP	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HDDNOHNL_01577	7.34e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HDDNOHNL_01578	2.22e-185	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HDDNOHNL_01579	5.63e-196	gntR	-	-	K	-	-	-	rpiR family
HDDNOHNL_01580	2.87e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HDDNOHNL_01581	7.06e-307	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDDNOHNL_01582	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HDDNOHNL_01583	2.26e-129	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDDNOHNL_01584	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDDNOHNL_01585	1.59e-242	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HDDNOHNL_01586	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HDDNOHNL_01587	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HDDNOHNL_01588	5.11e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HDDNOHNL_01589	9.48e-263	camS	-	-	S	-	-	-	sex pheromone
HDDNOHNL_01590	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HDDNOHNL_01591	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HDDNOHNL_01592	1.39e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HDDNOHNL_01593	1.13e-120	yebE	-	-	S	-	-	-	UPF0316 protein
HDDNOHNL_01594	2.01e-134	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HDDNOHNL_01595	1.97e-145	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HDDNOHNL_01596	7.78e-235	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HDDNOHNL_01597	1.37e-83	-	-	-	K	-	-	-	Helix-turn-helix domain
HDDNOHNL_01598	1.08e-71	-	-	-	-	-	-	-	-
HDDNOHNL_01599	1.66e-96	-	-	-	-	-	-	-	-
HDDNOHNL_01600	6.67e-30	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HDDNOHNL_01601	8.56e-38	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HDDNOHNL_01602	9.16e-61	-	-	-	L	-	-	-	Helix-turn-helix domain
HDDNOHNL_01604	3.56e-171	spoVK	-	-	O	ko:K06413	-	ko00000	ATPase family associated with various cellular activities (AAA)
HDDNOHNL_01606	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HDDNOHNL_01607	1.22e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HDDNOHNL_01608	8.45e-211	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
HDDNOHNL_01609	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HDDNOHNL_01610	4.51e-143	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HDDNOHNL_01611	4.16e-227	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HDDNOHNL_01612	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HDDNOHNL_01613	2.07e-161	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
HDDNOHNL_01614	1.35e-165	pgm3	-	-	G	-	-	-	Phosphoglycerate mutase family
HDDNOHNL_01615	1.61e-36	-	-	-	-	-	-	-	-
HDDNOHNL_01616	3.5e-64	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
HDDNOHNL_01617	4.6e-102	rppH3	-	-	F	-	-	-	NUDIX domain
HDDNOHNL_01618	5.95e-300	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HDDNOHNL_01619	1.81e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDDNOHNL_01620	2.93e-109	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HDDNOHNL_01621	3.22e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HDDNOHNL_01622	7.26e-92	-	-	-	K	-	-	-	MarR family
HDDNOHNL_01623	8.87e-191	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
HDDNOHNL_01624	6.26e-96	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDDNOHNL_01625	9.38e-317	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HDDNOHNL_01626	4.87e-180	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
HDDNOHNL_01627	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HDDNOHNL_01628	7.77e-197	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HDDNOHNL_01629	7.04e-108	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HDDNOHNL_01630	1.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDDNOHNL_01631	3.14e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDDNOHNL_01632	3.39e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HDDNOHNL_01633	2.3e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HDDNOHNL_01635	1.28e-54	-	-	-	-	-	-	-	-
HDDNOHNL_01636	2.07e-217	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDDNOHNL_01637	1.05e-234	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HDDNOHNL_01638	1.94e-95	gph1	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant
HDDNOHNL_01639	1.01e-188	-	-	-	-	-	-	-	-
HDDNOHNL_01640	8.84e-18	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HDDNOHNL_01641	2.02e-106	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HDDNOHNL_01642	2.45e-134	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HDDNOHNL_01643	1.48e-27	-	-	-	-	-	-	-	-
HDDNOHNL_01644	7.48e-96	-	-	-	F	-	-	-	Nudix hydrolase
HDDNOHNL_01645	1.23e-189	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HDDNOHNL_01646	6.12e-115	-	-	-	-	-	-	-	-
HDDNOHNL_01647	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HDDNOHNL_01648	3.8e-61	-	-	-	-	-	-	-	-
HDDNOHNL_01649	1.55e-89	-	-	-	O	-	-	-	OsmC-like protein
HDDNOHNL_01650	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HDDNOHNL_01651	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HDDNOHNL_01652	5.01e-229	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HDDNOHNL_01653	3.45e-231	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HDDNOHNL_01654	0.0	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HDDNOHNL_01655	5.47e-198	ribC1	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HDDNOHNL_01656	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HDDNOHNL_01657	1.79e-287	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HDDNOHNL_01658	1.36e-27	-	-	-	-	-	-	-	-
HDDNOHNL_01659	3.68e-107	-	-	-	K	-	-	-	Transcriptional regulator
HDDNOHNL_01660	7.8e-196	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HDDNOHNL_01661	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HDDNOHNL_01662	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HDDNOHNL_01663	4.45e-226	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HDDNOHNL_01664	3.49e-315	-	-	-	EGP	-	-	-	Major Facilitator
HDDNOHNL_01665	1.71e-116	-	-	-	V	-	-	-	VanZ like family
HDDNOHNL_01666	3.88e-46	-	-	-	-	-	-	-	-
HDDNOHNL_01667	5.45e-94	spx1	-	-	P	ko:K16509	-	ko00000	ArsC family
HDDNOHNL_01669	6.37e-186	-	-	-	-	-	-	-	-
HDDNOHNL_01670	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HDDNOHNL_01671	7.08e-197	-	-	-	G	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HDDNOHNL_01672	2.87e-168	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HDDNOHNL_01673	2.49e-95	-	-	-	-	-	-	-	-
HDDNOHNL_01674	3.38e-70	-	-	-	-	-	-	-	-
HDDNOHNL_01675	1.46e-263	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HDDNOHNL_01676	1.21e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDDNOHNL_01677	8.04e-190	-	3.1.3.23	-	S	ko:K07757	-	ko00000,ko01000	Sucrose-6F-phosphate phosphohydrolase
HDDNOHNL_01678	5.44e-159	-	-	-	T	-	-	-	EAL domain
HDDNOHNL_01679	0.0	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HDDNOHNL_01680	0.0	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
HDDNOHNL_01681	2.54e-225	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
HDDNOHNL_01682	3.72e-145	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HDDNOHNL_01683	7.32e-292	sat	2.7.7.4	-	H	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HDDNOHNL_01684	0.0	-	-	-	S	-	-	-	Protein conserved in bacteria
HDDNOHNL_01685	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HDDNOHNL_01686	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HDDNOHNL_01687	8.01e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
HDDNOHNL_01688	4.91e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
HDDNOHNL_01689	3.89e-237	-	-	-	-	-	-	-	-
HDDNOHNL_01690	9.03e-16	-	-	-	-	-	-	-	-
HDDNOHNL_01691	4.29e-87	-	-	-	-	-	-	-	-
HDDNOHNL_01694	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
HDDNOHNL_01695	7.12e-62	-	-	-	-	-	-	-	-
HDDNOHNL_01696	8.82e-119	-	-	-	-	-	-	-	-
HDDNOHNL_01697	2.2e-111	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HDDNOHNL_01698	1.23e-145	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HDDNOHNL_01699	4.56e-78	-	-	-	-	-	-	-	-
HDDNOHNL_01700	5.37e-74	-	-	-	-	-	-	-	-
HDDNOHNL_01701	9.01e-179	agrA	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HDDNOHNL_01702	2.08e-283	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HDDNOHNL_01703	7.83e-140	-	-	-	-	-	-	-	-
HDDNOHNL_01704	1.89e-189	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HDDNOHNL_01705	9.36e-205	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HDDNOHNL_01706	1.64e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
HDDNOHNL_01707	5.2e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HDDNOHNL_01708	6.96e-198	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HDDNOHNL_01710	2.57e-226	-	-	-	K	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
HDDNOHNL_01711	3.06e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HDDNOHNL_01712	3.34e-160	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HDDNOHNL_01714	3e-315	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
HDDNOHNL_01715	3.55e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HDDNOHNL_01716	2.07e-155	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HDDNOHNL_01717	5.01e-229	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HDDNOHNL_01718	3.05e-193	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDDNOHNL_01719	1.13e-221	ugpA	-	-	U	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDDNOHNL_01720	2.92e-258	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
HDDNOHNL_01721	2.16e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HDDNOHNL_01722	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HDDNOHNL_01723	3.03e-193	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HDDNOHNL_01724	5.04e-176	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HDDNOHNL_01725	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HDDNOHNL_01726	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HDDNOHNL_01727	3.58e-161	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HDDNOHNL_01728	3.03e-122	mraW1	-	-	J	-	-	-	Putative rRNA methylase
HDDNOHNL_01729	9.32e-40	-	-	-	-	-	-	-	-
HDDNOHNL_01730	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HDDNOHNL_01731	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HDDNOHNL_01732	0.0	-	-	-	S	-	-	-	Pfam Methyltransferase
HDDNOHNL_01733	4.36e-185	-	-	-	N	-	-	-	Cell shape-determining protein MreB
HDDNOHNL_01734	1.37e-60	-	-	-	N	-	-	-	Cell shape-determining protein MreB
HDDNOHNL_01735	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
HDDNOHNL_01736	2.78e-273	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HDDNOHNL_01737	3.35e-157	-	-	-	-	-	-	-	-
HDDNOHNL_01738	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HDDNOHNL_01739	2.75e-216	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HDDNOHNL_01740	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HDDNOHNL_01741	6.21e-241	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HDDNOHNL_01742	2.19e-291	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HDDNOHNL_01744	3.47e-134	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HDDNOHNL_01745	2.98e-46	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HDDNOHNL_01746	1.58e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HDDNOHNL_01747	1.25e-124	-	-	-	-	-	-	-	-
HDDNOHNL_01748	6.36e-237	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
HDDNOHNL_01749	3.26e-119	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
HDDNOHNL_01760	4.75e-157	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HDDNOHNL_01761	1.13e-171	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HDDNOHNL_01762	4.87e-156	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HDDNOHNL_01763	4.32e-294	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HDDNOHNL_01764	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HDDNOHNL_01765	1.96e-137	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HDDNOHNL_01766	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HDDNOHNL_01767	1.17e-135	-	-	-	K	-	-	-	transcriptional regulator
HDDNOHNL_01768	2.04e-158	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HDDNOHNL_01769	1.49e-63	-	-	-	-	-	-	-	-
HDDNOHNL_01770	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HDDNOHNL_01771	5.06e-236	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HDDNOHNL_01772	2.87e-56	-	-	-	-	-	-	-	-
HDDNOHNL_01773	1.6e-73	-	-	-	-	-	-	-	-
HDDNOHNL_01774	6.86e-311	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDDNOHNL_01775	2.78e-167	yidA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HDDNOHNL_01776	9.86e-65	-	-	-	-	-	-	-	-
HDDNOHNL_01777	2.58e-163	rrp2	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HDDNOHNL_01778	1.72e-315	hpk2	-	-	T	-	-	-	Histidine kinase
HDDNOHNL_01779	2.2e-86	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HDDNOHNL_01780	0.0	ydiC	-	-	EGP	-	-	-	Major Facilitator
HDDNOHNL_01781	3.13e-55	-	-	-	-	-	-	-	-
HDDNOHNL_01782	6.37e-52	-	-	-	-	-	-	-	-
HDDNOHNL_01783	4.5e-150	-	-	-	-	-	-	-	-
HDDNOHNL_01784	4.02e-301	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HDDNOHNL_01785	8.62e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDDNOHNL_01786	8.9e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
HDDNOHNL_01787	2.73e-92	-	-	-	-	-	-	-	-
HDDNOHNL_01788	3.37e-129	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HDDNOHNL_01789	0.0	tagF2	2.7.8.12	-	H	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HDDNOHNL_01790	5.71e-306	tagB	2.7.8.12, 2.7.8.45	-	M	ko:K09809,ko:K21591	-	ko00000,ko01000	glycerophosphotransferase
HDDNOHNL_01791	1.21e-94	tagD	2.7.7.15, 2.7.7.39	-	IM	ko:K00968,ko:K00980	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Glycerol-3-phosphate cytidylyltransferase
HDDNOHNL_01792	2.6e-185	-	-	-	-	-	-	-	-
HDDNOHNL_01793	0.0	pts5ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HDDNOHNL_01794	0.0	pts4ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDDNOHNL_01795	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HDDNOHNL_01796	1.68e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HDDNOHNL_01797	6.35e-56	-	-	-	-	-	-	-	-
HDDNOHNL_01798	7.55e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
HDDNOHNL_01799	1.27e-181	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HDDNOHNL_01800	6.72e-203	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HDDNOHNL_01801	2.52e-209	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HDDNOHNL_01802	7.87e-266	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HDDNOHNL_01803	2.13e-124	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
HDDNOHNL_01804	1.82e-126	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
HDDNOHNL_01805	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HDDNOHNL_01806	2.41e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HDDNOHNL_01807	1.73e-89	-	-	-	-	-	-	-	-
HDDNOHNL_01808	2.37e-123	-	-	-	-	-	-	-	-
HDDNOHNL_01809	5.92e-67	-	-	-	-	-	-	-	-
HDDNOHNL_01810	4.81e-76	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HDDNOHNL_01811	1.21e-111	-	-	-	-	-	-	-	-
HDDNOHNL_01812	1.76e-280	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HDDNOHNL_01813	5.33e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDDNOHNL_01814	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
HDDNOHNL_01815	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HDDNOHNL_01816	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HDDNOHNL_01817	7.02e-126	-	-	-	K	-	-	-	Helix-turn-helix domain
HDDNOHNL_01818	3.91e-283	-	-	-	C	-	-	-	FAD dependent oxidoreductase
HDDNOHNL_01819	1.82e-220	-	-	-	P	-	-	-	Major Facilitator Superfamily
HDDNOHNL_01820	3.16e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HDDNOHNL_01821	2.32e-43	ygzD	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
HDDNOHNL_01822	1.2e-91	-	-	-	-	-	-	-	-
HDDNOHNL_01823	1.05e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HDDNOHNL_01824	5.3e-202	dkgB	-	-	S	-	-	-	reductase
HDDNOHNL_01825	6.07e-117	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HDDNOHNL_01826	2.02e-131	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC transporter permease
HDDNOHNL_01827	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HDDNOHNL_01828	1.5e-150	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HDDNOHNL_01829	4.15e-191	yxeH	-	-	S	-	-	-	hydrolase
HDDNOHNL_01830	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HDDNOHNL_01831	1.14e-202	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
HDDNOHNL_01832	2.87e-101	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HDDNOHNL_01833	2.96e-89	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HDDNOHNL_01834	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HDDNOHNL_01835	5.84e-312	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HDDNOHNL_01836	2.28e-290	sdaC	-	-	E	ko:K03837	-	ko00000,ko02000	amino acid
HDDNOHNL_01837	7.51e-159	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HDDNOHNL_01838	2.81e-202	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HDDNOHNL_01839	6.59e-170	-	-	-	S	-	-	-	YheO-like PAS domain
HDDNOHNL_01840	4.01e-36	-	-	-	-	-	-	-	-
HDDNOHNL_01841	2.08e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HDDNOHNL_01842	1.26e-305	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HDDNOHNL_01843	1.91e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HDDNOHNL_01844	2.57e-274	-	-	-	J	-	-	-	translation release factor activity
HDDNOHNL_01845	3.14e-164	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HDDNOHNL_01846	5.35e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HDDNOHNL_01847	1.6e-194	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HDDNOHNL_01848	1.84e-189	-	-	-	-	-	-	-	-
HDDNOHNL_01849	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HDDNOHNL_01850	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HDDNOHNL_01851	9.32e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HDDNOHNL_01852	4.79e-273	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HDDNOHNL_01853	2.58e-85	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HDDNOHNL_01854	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HDDNOHNL_01855	1.37e-248	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	ABC transporter, substratebinding protein
HDDNOHNL_01856	3.03e-202	-	-	-	U	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDDNOHNL_01857	5.79e-171	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HDDNOHNL_01858	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HDDNOHNL_01859	7.48e-260	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HDDNOHNL_01860	8.87e-245	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HDDNOHNL_01861	2.29e-292	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HDDNOHNL_01862	2.36e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HDDNOHNL_01863	3.52e-273	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
HDDNOHNL_01864	1.52e-240	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HDDNOHNL_01865	1.3e-110	queT	-	-	S	-	-	-	QueT transporter
HDDNOHNL_01866	1.4e-147	-	-	-	S	-	-	-	(CBS) domain
HDDNOHNL_01867	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HDDNOHNL_01868	2.79e-226	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HDDNOHNL_01869	1.43e-129	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HDDNOHNL_01870	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HDDNOHNL_01871	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HDDNOHNL_01872	7.72e-57	yabO	-	-	J	-	-	-	S4 domain protein
HDDNOHNL_01874	2.02e-83	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HDDNOHNL_01875	1.07e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HDDNOHNL_01876	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HDDNOHNL_01877	4.3e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HDDNOHNL_01878	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HDDNOHNL_01879	1.93e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HDDNOHNL_01880	5.33e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HDDNOHNL_01881	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HDDNOHNL_01882	1.97e-110	-	-	-	S	-	-	-	Pfam:DUF3816
HDDNOHNL_01883	1.21e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HDDNOHNL_01884	1.27e-143	-	-	-	-	-	-	-	-
HDDNOHNL_01885	1.08e-229	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HDDNOHNL_01886	3.84e-185	-	-	-	S	-	-	-	Peptidase_C39 like family
HDDNOHNL_01887	1.04e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HDDNOHNL_01888	3.38e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HDDNOHNL_01889	9.38e-189	-	-	-	KT	-	-	-	helix_turn_helix, mercury resistance
HDDNOHNL_01890	3.41e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HDDNOHNL_01891	1.86e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HDDNOHNL_01892	1.2e-240	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HDDNOHNL_01893	1.18e-155	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDDNOHNL_01894	2.76e-117	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
HDDNOHNL_01895	5.72e-238	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HDDNOHNL_01896	3.55e-127	ywjB	-	-	H	-	-	-	RibD C-terminal domain
HDDNOHNL_01897	9.35e-257	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HDDNOHNL_01898	7.1e-152	-	-	-	S	-	-	-	Membrane
HDDNOHNL_01899	2.11e-199	mleP3	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HDDNOHNL_01900	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
HDDNOHNL_01901	4.32e-261	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HDDNOHNL_01902	7.22e-163	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HDDNOHNL_01903	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HDDNOHNL_01904	4.03e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HDDNOHNL_01905	8.99e-133	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HDDNOHNL_01906	2.17e-222	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HDDNOHNL_01907	5.9e-194	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HDDNOHNL_01908	0.0	tagE5	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
HDDNOHNL_01909	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HDDNOHNL_01911	2.24e-78	-	-	-	M	-	-	-	LysM domain
HDDNOHNL_01912	6.5e-119	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
HDDNOHNL_01913	1.65e-212	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDDNOHNL_01914	3.91e-269	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HDDNOHNL_01915	6.27e-166	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDDNOHNL_01916	4.72e-72	cmd	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HDDNOHNL_01917	4.77e-100	yphH	-	-	S	-	-	-	Cupin domain
HDDNOHNL_01918	5.19e-103	-	-	-	K	-	-	-	transcriptional regulator, MerR family
HDDNOHNL_01919	4.87e-298	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HDDNOHNL_01920	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HDDNOHNL_01921	1.74e-156	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDDNOHNL_01923	1.19e-150	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HDDNOHNL_01924	3.18e-141	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HDDNOHNL_01925	1.03e-150	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HDDNOHNL_01927	4.86e-111	-	-	-	-	-	-	-	-
HDDNOHNL_01928	1.04e-110	yvbK	-	-	K	-	-	-	GNAT family
HDDNOHNL_01929	9.76e-50	-	-	-	-	-	-	-	-
HDDNOHNL_01930	2.81e-64	-	-	-	-	-	-	-	-
HDDNOHNL_01931	7.44e-143	pgm8	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
HDDNOHNL_01932	6.09e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
HDDNOHNL_01933	1.51e-200	-	-	-	K	-	-	-	LysR substrate binding domain
HDDNOHNL_01934	1.52e-135	-	-	-	GM	-	-	-	NAD(P)H-binding
HDDNOHNL_01935	1.66e-247	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HDDNOHNL_01936	2.9e-194	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HDDNOHNL_01937	1.28e-45	-	-	-	-	-	-	-	-
HDDNOHNL_01938	2.1e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HDDNOHNL_01939	2.09e-124	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HDDNOHNL_01940	1.76e-162	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HDDNOHNL_01941	1.03e-40	-	-	-	-	-	-	-	-
HDDNOHNL_01942	0.0	-	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
HDDNOHNL_01943	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HDDNOHNL_01945	9.45e-160	-	-	-	S	-	-	-	YjbR
HDDNOHNL_01946	4.04e-37	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HDDNOHNL_01947	3.23e-215	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HDDNOHNL_01948	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HDDNOHNL_01949	1.44e-255	glmS2	-	-	M	-	-	-	SIS domain
HDDNOHNL_01950	2.07e-35	-	-	-	S	-	-	-	Belongs to the LOG family
HDDNOHNL_01951	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HDDNOHNL_01952	3.98e-315	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HDDNOHNL_01953	5.85e-92	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HDDNOHNL_01954	5.38e-92	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HDDNOHNL_01955	4.75e-112	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
HDDNOHNL_01956	1.07e-206	-	-	-	GM	-	-	-	NmrA-like family
HDDNOHNL_01957	2.14e-86	-	-	-	K	ko:K22296	-	ko00000,ko03000	Winged helix DNA-binding domain
HDDNOHNL_01958	9.97e-94	spxA	-	-	P	ko:K16509	-	ko00000	ArsC family
HDDNOHNL_01959	3.46e-87	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HDDNOHNL_01960	1.7e-70	-	-	-	-	-	-	-	-
HDDNOHNL_01961	4.98e-275	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
HDDNOHNL_01962	2.11e-82	-	-	-	-	-	-	-	-
HDDNOHNL_01963	1.36e-112	-	-	-	-	-	-	-	-
HDDNOHNL_01964	4.58e-103	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HDDNOHNL_01965	3.78e-73	-	-	-	-	-	-	-	-
HDDNOHNL_01966	4.79e-21	-	-	-	-	-	-	-	-
HDDNOHNL_01967	3.57e-150	-	-	-	GM	-	-	-	NmrA-like family
HDDNOHNL_01968	2.52e-107	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HDDNOHNL_01969	9.43e-203	-	-	-	EG	-	-	-	EamA-like transporter family
HDDNOHNL_01970	2.66e-155	-	-	-	S	-	-	-	membrane
HDDNOHNL_01971	1.47e-144	-	-	-	S	-	-	-	VIT family
HDDNOHNL_01972	4.38e-243	pva2	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HDDNOHNL_01973	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HDDNOHNL_01974	8.01e-97	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HDDNOHNL_01975	4.26e-54	-	-	-	-	-	-	-	-
HDDNOHNL_01976	3.43e-96	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
HDDNOHNL_01977	8.8e-315	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HDDNOHNL_01978	7.21e-35	-	-	-	-	-	-	-	-
HDDNOHNL_01979	2.55e-65	-	-	-	-	-	-	-	-
HDDNOHNL_01980	2.51e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF1398)
HDDNOHNL_01981	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HDDNOHNL_01982	1.77e-282	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HDDNOHNL_01983	9.92e-230	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HDDNOHNL_01984	6.1e-101	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HDDNOHNL_01985	1.14e-110	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HDDNOHNL_01986	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HDDNOHNL_01987	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HDDNOHNL_01988	2.3e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HDDNOHNL_01989	1.36e-209	yvgN	-	-	C	-	-	-	Aldo keto reductase
HDDNOHNL_01990	2.57e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
HDDNOHNL_01991	1.7e-101	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HDDNOHNL_01992	1.5e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HDDNOHNL_01993	2.69e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HDDNOHNL_01994	5.94e-118	ymdB	-	-	S	-	-	-	Macro domain protein
HDDNOHNL_01995	6.47e-124	-	-	-	K	ko:K22041	-	ko00000,ko03000	transcriptional regulator
HDDNOHNL_01996	1.58e-66	-	-	-	-	-	-	-	-
HDDNOHNL_01997	2.41e-212	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HDDNOHNL_01998	0.0	-	-	-	-	-	-	-	-
HDDNOHNL_01999	2.08e-161	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HDDNOHNL_02000	1.56e-71	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HDDNOHNL_02001	3.17e-170	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HDDNOHNL_02002	1.63e-176	yesN	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HDDNOHNL_02003	3.08e-113	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HDDNOHNL_02004	3.81e-150	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDDNOHNL_02005	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HDDNOHNL_02006	4.45e-38	-	-	-	-	-	-	-	-
HDDNOHNL_02007	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
HDDNOHNL_02008	1.88e-96	-	-	-	M	-	-	-	PFAM NLP P60 protein
HDDNOHNL_02009	6.18e-71	-	-	-	-	-	-	-	-
HDDNOHNL_02010	5.77e-81	-	-	-	-	-	-	-	-
HDDNOHNL_02012	9.39e-84	-	-	-	-	-	-	-	-
HDDNOHNL_02014	1.12e-134	-	-	-	K	-	-	-	transcriptional regulator
HDDNOHNL_02015	4.84e-230	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HDDNOHNL_02016	4.16e-175	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HDDNOHNL_02017	1.5e-165	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
HDDNOHNL_02018	8.06e-232	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HDDNOHNL_02019	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HDDNOHNL_02020	9.44e-183	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HDDNOHNL_02021	5.73e-73	trxA3	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
HDDNOHNL_02022	4.82e-55	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
HDDNOHNL_02023	1.01e-26	-	-	-	-	-	-	-	-
HDDNOHNL_02024	4.27e-126	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HDDNOHNL_02025	2.98e-44	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
HDDNOHNL_02026	1.82e-152	rcfA	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HDDNOHNL_02027	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HDDNOHNL_02028	1.06e-106	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HDDNOHNL_02029	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HDDNOHNL_02030	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HDDNOHNL_02031	1.83e-235	-	-	-	S	-	-	-	Cell surface protein
HDDNOHNL_02032	8.67e-160	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HDDNOHNL_02033	4.23e-129	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HDDNOHNL_02034	7.83e-60	-	-	-	-	-	-	-	-
HDDNOHNL_02035	8.19e-134	yezE	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
HDDNOHNL_02036	1.03e-65	-	-	-	-	-	-	-	-
HDDNOHNL_02037	9.34e-317	-	-	-	S	-	-	-	Putative metallopeptidase domain
HDDNOHNL_02038	3.7e-279	-	-	-	S	-	-	-	associated with various cellular activities
HDDNOHNL_02039	1.95e-140	aqpZ	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HDDNOHNL_02040	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HDDNOHNL_02041	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HDDNOHNL_02042	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HDDNOHNL_02043	2.9e-293	-	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
HDDNOHNL_02044	0.0	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HDDNOHNL_02045	5.91e-297	-	-	-	P	ko:K06610	-	ko00000,ko02000	Major Facilitator Superfamily
HDDNOHNL_02046	1.29e-235	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HDDNOHNL_02047	3.38e-50	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HDDNOHNL_02048	1.11e-33	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HDDNOHNL_02049	6.61e-29	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HDDNOHNL_02050	5.55e-100	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HDDNOHNL_02051	1.55e-230	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HDDNOHNL_02052	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HDDNOHNL_02053	2.97e-244	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HDDNOHNL_02054	1.29e-232	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HDDNOHNL_02055	3.72e-14	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
HDDNOHNL_02056	9.51e-135	-	-	-	-	-	-	-	-
HDDNOHNL_02057	4.84e-227	-	-	-	-	-	-	-	-
HDDNOHNL_02058	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HDDNOHNL_02059	7.1e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HDDNOHNL_02060	2.64e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HDDNOHNL_02061	2.15e-209	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
HDDNOHNL_02062	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HDDNOHNL_02063	2.36e-285	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HDDNOHNL_02064	8.65e-228	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HDDNOHNL_02065	1.21e-268	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HDDNOHNL_02066	3.95e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HDDNOHNL_02067	6.45e-111	-	-	-	-	-	-	-	-
HDDNOHNL_02068	4.86e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HDDNOHNL_02069	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HDDNOHNL_02070	3.45e-240	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HDDNOHNL_02071	2.16e-39	-	-	-	-	-	-	-	-
HDDNOHNL_02072	2.62e-168	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HDDNOHNL_02073	5.35e-220	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HDDNOHNL_02074	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HDDNOHNL_02075	1.02e-155	-	-	-	S	-	-	-	repeat protein
HDDNOHNL_02076	2.41e-157	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HDDNOHNL_02077	0.0	-	-	-	N	-	-	-	domain, Protein
HDDNOHNL_02078	2.02e-247	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HDDNOHNL_02079	4.17e-153	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
HDDNOHNL_02080	4.64e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HDDNOHNL_02081	9.64e-307	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HDDNOHNL_02082	6.7e-285	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HDDNOHNL_02083	4.94e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HDDNOHNL_02084	8.09e-275	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HDDNOHNL_02085	5.85e-158	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HDDNOHNL_02086	7.74e-47	-	-	-	-	-	-	-	-
HDDNOHNL_02087	3.51e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HDDNOHNL_02088	3.46e-242	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HDDNOHNL_02089	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HDDNOHNL_02090	6.52e-124	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HDDNOHNL_02091	2.06e-187	ylmH	-	-	S	-	-	-	S4 domain protein
HDDNOHNL_02092	6.45e-49	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HDDNOHNL_02093	1.56e-93	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HDDNOHNL_02094	9.39e-295	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HDDNOHNL_02095	3.55e-312	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HDDNOHNL_02096	2.34e-208	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HDDNOHNL_02097	2.04e-252	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HDDNOHNL_02098	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HDDNOHNL_02099	2.81e-231	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HDDNOHNL_02100	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HDDNOHNL_02101	7.01e-76	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HDDNOHNL_02102	1.74e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HDDNOHNL_02103	7.24e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HDDNOHNL_02104	3.22e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
HDDNOHNL_02105	4.1e-223	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HDDNOHNL_02106	4.54e-54	-	-	-	-	-	-	-	-
HDDNOHNL_02108	8.83e-317	-	-	-	EGP	-	-	-	Major Facilitator
HDDNOHNL_02109	5.61e-216	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HDDNOHNL_02110	4.26e-109	cvpA	-	-	S	-	-	-	Colicin V production protein
HDDNOHNL_02111	9.61e-84	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HDDNOHNL_02112	1.59e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HDDNOHNL_02113	1.8e-134	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HDDNOHNL_02114	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HDDNOHNL_02115	2.01e-134	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HDDNOHNL_02116	5.59e-271	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
HDDNOHNL_02117	3.91e-124	tag2	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HDDNOHNL_02118	8.03e-28	-	-	-	-	-	-	-	-
HDDNOHNL_02119	1.3e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HDDNOHNL_02120	7.27e-73	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HDDNOHNL_02121	2.94e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HDDNOHNL_02122	1.97e-60	qacH	-	-	U	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HDDNOHNL_02123	1.63e-77	-	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HDDNOHNL_02124	1.38e-275	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HDDNOHNL_02125	3.1e-228	ydbI	-	-	K	-	-	-	AI-2E family transporter
HDDNOHNL_02126	1.07e-211	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HDDNOHNL_02127	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HDDNOHNL_02129	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
HDDNOHNL_02130	4.62e-107	-	-	-	-	-	-	-	-
HDDNOHNL_02132	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HDDNOHNL_02133	1.02e-187	ptp2	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HDDNOHNL_02134	4.17e-235	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HDDNOHNL_02135	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HDDNOHNL_02136	3.66e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HDDNOHNL_02137	2.05e-72	-	-	-	S	-	-	-	Enterocin A Immunity
HDDNOHNL_02138	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HDDNOHNL_02139	1.49e-253	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HDDNOHNL_02140	9.07e-233	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
HDDNOHNL_02141	2.85e-210	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
HDDNOHNL_02142	0.0	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
HDDNOHNL_02143	7.02e-151	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
HDDNOHNL_02144	1.03e-34	-	-	-	-	-	-	-	-
HDDNOHNL_02145	1.56e-185	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HDDNOHNL_02146	2.88e-164	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
HDDNOHNL_02147	4.14e-84	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
HDDNOHNL_02148	2.8e-135	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HDDNOHNL_02149	1.33e-100	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HDDNOHNL_02150	7.47e-77	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HDDNOHNL_02151	6.46e-49	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
HDDNOHNL_02152	1.28e-77	-	-	-	S	-	-	-	Enterocin A Immunity
HDDNOHNL_02153	1.55e-114	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HDDNOHNL_02154	1.16e-135	-	-	-	-	-	-	-	-
HDDNOHNL_02155	8.44e-304	-	-	-	S	-	-	-	module of peptide synthetase
HDDNOHNL_02156	2.95e-100	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HDDNOHNL_02158	1.25e-164	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
HDDNOHNL_02159	0.0	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDDNOHNL_02160	7.54e-200	-	-	-	GM	-	-	-	NmrA-like family
HDDNOHNL_02161	4.08e-101	-	-	-	K	-	-	-	MerR family regulatory protein
HDDNOHNL_02162	2.69e-316	dinF	-	-	V	-	-	-	MatE
HDDNOHNL_02163	1.79e-42	-	-	-	-	-	-	-	-
HDDNOHNL_02166	8.2e-102	yybD	-	-	S	ko:K02348	-	ko00000	Acetyltransferase (GNAT) domain
HDDNOHNL_02167	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HDDNOHNL_02168	4.64e-106	-	-	-	-	-	-	-	-
HDDNOHNL_02169	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HDDNOHNL_02170	1.04e-136	-	-	-	-	-	-	-	-
HDDNOHNL_02171	0.0	celR	-	-	K	-	-	-	PRD domain
HDDNOHNL_02172	1.34e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HDDNOHNL_02173	2.37e-68	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HDDNOHNL_02174	4.9e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HDDNOHNL_02175	1.71e-277	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDDNOHNL_02176	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDDNOHNL_02177	3.5e-271	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
HDDNOHNL_02178	2.34e-146	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HDDNOHNL_02179	1.65e-46	dltC2	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDDNOHNL_02180	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	Alanine-glyoxylate amino-transferase
HDDNOHNL_02181	8.08e-133	argO	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
HDDNOHNL_02182	5.58e-271	arcT	-	-	E	-	-	-	Aminotransferase
HDDNOHNL_02183	2.07e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HDDNOHNL_02184	2.43e-18	-	-	-	-	-	-	-	-
HDDNOHNL_02185	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HDDNOHNL_02186	9.94e-71	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HDDNOHNL_02187	4.47e-296	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HDDNOHNL_02188	0.0	yhaN	-	-	L	-	-	-	AAA domain
HDDNOHNL_02189	1.03e-240	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HDDNOHNL_02190	1.05e-272	-	-	-	-	-	-	-	-
HDDNOHNL_02191	2.41e-233	-	-	-	M	-	-	-	Peptidase family S41
HDDNOHNL_02192	1.09e-225	-	-	-	K	-	-	-	LysR substrate binding domain
HDDNOHNL_02193	9.9e-144	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HDDNOHNL_02194	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HDDNOHNL_02195	4.43e-129	-	-	-	-	-	-	-	-
HDDNOHNL_02196	1.17e-100	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
HDDNOHNL_02197	1.15e-235	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
HDDNOHNL_02198	7.78e-20	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HDDNOHNL_02199	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HDDNOHNL_02200	4.29e-26	-	-	-	S	-	-	-	NUDIX domain
HDDNOHNL_02201	0.0	-	-	-	S	-	-	-	membrane
HDDNOHNL_02202	4.26e-218	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HDDNOHNL_02203	2.61e-95	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HDDNOHNL_02204	2.08e-284	ribA	3.5.4.25, 4.1.99.12	-	H	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HDDNOHNL_02205	1.23e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HDDNOHNL_02206	5.21e-137	-	-	-	S	ko:K09962	-	ko00000	Nucleotidyltransferase
HDDNOHNL_02207	1.96e-137	-	-	-	-	-	-	-	-
HDDNOHNL_02208	3.3e-151	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HDDNOHNL_02209	1.08e-95	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDDNOHNL_02210	1.36e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
HDDNOHNL_02211	1.23e-57	-	-	-	S	-	-	-	Cupredoxin-like domain
HDDNOHNL_02212	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HDDNOHNL_02213	6.8e-272	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
HDDNOHNL_02214	4.2e-286	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HDDNOHNL_02215	4.8e-86	lysM	-	-	M	-	-	-	LysM domain
HDDNOHNL_02216	0.0	-	-	-	E	-	-	-	Amino Acid
HDDNOHNL_02217	1.43e-184	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HDDNOHNL_02218	1.97e-92	-	-	-	-	-	-	-	-
HDDNOHNL_02220	2.96e-209	yhxD	-	-	IQ	-	-	-	KR domain
HDDNOHNL_02221	3.23e-290	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
HDDNOHNL_02223	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HDDNOHNL_02224	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDDNOHNL_02225	2.31e-277	-	-	-	-	-	-	-	-
HDDNOHNL_02226	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HDDNOHNL_02227	7.43e-97	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HDDNOHNL_02228	3.55e-281	-	-	-	T	-	-	-	diguanylate cyclase
HDDNOHNL_02229	1.92e-155	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
HDDNOHNL_02230	3.57e-120	-	-	-	-	-	-	-	-
HDDNOHNL_02231	5.76e-212	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HDDNOHNL_02232	1.58e-72	nudA	-	-	S	-	-	-	ASCH
HDDNOHNL_02233	5.71e-138	-	-	-	S	-	-	-	SdpI/YhfL protein family
HDDNOHNL_02234	7.94e-126	-	-	-	M	-	-	-	Lysin motif
HDDNOHNL_02235	4.61e-101	-	-	-	M	-	-	-	LysM domain
HDDNOHNL_02236	2.1e-99	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HDDNOHNL_02237	4.32e-235	-	-	-	GM	-	-	-	Male sterility protein
HDDNOHNL_02238	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDDNOHNL_02239	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDDNOHNL_02240	7.47e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HDDNOHNL_02241	3.91e-100	pts23A	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HDDNOHNL_02242	1.24e-194	-	-	-	K	-	-	-	Helix-turn-helix domain
HDDNOHNL_02243	1.21e-73	-	-	-	-	-	-	-	-
HDDNOHNL_02244	1.58e-204	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HDDNOHNL_02245	2.03e-84	-	-	-	-	-	-	-	-
HDDNOHNL_02246	3.93e-38	-	-	-	P	-	-	-	Concanavalin A-like lectin/glucanases superfamily
HDDNOHNL_02247	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDDNOHNL_02248	7.89e-124	-	-	-	P	-	-	-	Cadmium resistance transporter
HDDNOHNL_02249	8.58e-65	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HDDNOHNL_02250	1.81e-150	-	-	-	S	-	-	-	SNARE associated Golgi protein
HDDNOHNL_02251	7.03e-62	-	-	-	-	-	-	-	-
HDDNOHNL_02252	1.18e-94	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
HDDNOHNL_02253	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HDDNOHNL_02254	3.35e-157	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HDDNOHNL_02255	2.88e-106	gtcA3	-	-	S	-	-	-	GtrA-like protein
HDDNOHNL_02256	2.81e-167	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
HDDNOHNL_02257	3.73e-131	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HDDNOHNL_02258	2.33e-283	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HDDNOHNL_02259	1.07e-131	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HDDNOHNL_02260	1.8e-249	-	-	-	C	-	-	-	Aldo/keto reductase family
HDDNOHNL_02262	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDDNOHNL_02263	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDDNOHNL_02264	6.27e-316	-	-	-	EGP	-	-	-	Major Facilitator
HDDNOHNL_02269	8.63e-259	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HDDNOHNL_02270	1.23e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
HDDNOHNL_02271	6.88e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HDDNOHNL_02272	1.36e-198	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HDDNOHNL_02273	1.39e-134	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HDDNOHNL_02274	8.76e-126	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HDDNOHNL_02275	2.09e-287	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HDDNOHNL_02276	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HDDNOHNL_02277	5.69e-191	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HDDNOHNL_02278	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HDDNOHNL_02279	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
HDDNOHNL_02280	1.35e-264	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HDDNOHNL_02281	1.54e-219	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HDDNOHNL_02282	1.76e-298	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HDDNOHNL_02283	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HDDNOHNL_02284	9.55e-205	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HDDNOHNL_02285	1.01e-167	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HDDNOHNL_02286	0.0	-	-	-	-	-	-	-	-
HDDNOHNL_02287	2e-52	-	-	-	S	-	-	-	Cytochrome B5
HDDNOHNL_02288	8.68e-118	pts21A	-	-	G	ko:K02755	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HDDNOHNL_02289	6.48e-135	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HDDNOHNL_02290	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HDDNOHNL_02291	3.51e-252	galM3	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HDDNOHNL_02292	3.69e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HDDNOHNL_02293	1.42e-245	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HDDNOHNL_02294	2.86e-85	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
HDDNOHNL_02295	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HDDNOHNL_02296	1.23e-228	apbE3	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HDDNOHNL_02297	5.56e-167	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HDDNOHNL_02298	1.33e-274	-	-	-	G	-	-	-	Transporter
HDDNOHNL_02299	1.66e-215	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HDDNOHNL_02300	5.79e-209	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HDDNOHNL_02301	5.78e-269	-	-	-	G	-	-	-	Major Facilitator Superfamily
HDDNOHNL_02302	2.97e-83	-	-	-	-	-	-	-	-
HDDNOHNL_02303	1.78e-198	estA	-	-	S	-	-	-	Putative esterase
HDDNOHNL_02304	5.44e-174	-	-	-	K	-	-	-	UTRA domain
HDDNOHNL_02305	0.0	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDDNOHNL_02306	1.67e-208	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HDDNOHNL_02307	6.87e-202	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
HDDNOHNL_02308	2.26e-269	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HDDNOHNL_02309	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDDNOHNL_02310	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDDNOHNL_02311	3.72e-200	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HDDNOHNL_02312	0.0	pbg9	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDDNOHNL_02313	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDDNOHNL_02314	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDDNOHNL_02315	1.3e-203	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HDDNOHNL_02316	0.0	treP	2.4.1.64	GH65	G	ko:K05342	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HDDNOHNL_02317	1.08e-221	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
HDDNOHNL_02318	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HDDNOHNL_02319	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HDDNOHNL_02320	6.39e-169	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HDDNOHNL_02321	8.05e-166	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HDDNOHNL_02322	1.9e-230	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
HDDNOHNL_02323	2.26e-209	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HDDNOHNL_02324	6.87e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HDDNOHNL_02325	1.19e-201	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HDDNOHNL_02326	1.6e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HDDNOHNL_02327	1.63e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HDDNOHNL_02329	2.53e-106	mutR	-	-	K	ko:K20373,ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
HDDNOHNL_02330	1.81e-273	-	-	-	EGP	ko:K02030	-	ko00000,ko00002,ko02000	Drug resistance transporter Bcr CflA subfamily
HDDNOHNL_02331	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HDDNOHNL_02332	4.64e-92	-	-	-	F	-	-	-	DNA mismatch repair protein MutT
HDDNOHNL_02333	1.12e-205	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HDDNOHNL_02334	3.56e-170	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HDDNOHNL_02335	7.71e-228	-	-	-	-	-	-	-	-
HDDNOHNL_02336	1.37e-290	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HDDNOHNL_02337	1.36e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HDDNOHNL_02338	4.87e-243	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HDDNOHNL_02339	1.6e-77	chpA	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HDDNOHNL_02340	5.9e-46	-	-	-	-	-	-	-	-
HDDNOHNL_02341	1.69e-97	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HDDNOHNL_02342	9.68e-34	-	-	-	-	-	-	-	-
HDDNOHNL_02343	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDDNOHNL_02344	2.69e-166	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HDDNOHNL_02345	2.35e-243	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HDDNOHNL_02346	1.38e-179	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HDDNOHNL_02347	0.0	-	-	-	L	-	-	-	DNA helicase
HDDNOHNL_02348	4.23e-64	axe	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
HDDNOHNL_02349	3.74e-144	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HDDNOHNL_02350	4.56e-144	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HDDNOHNL_02351	8.02e-152	plnU	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HDDNOHNL_02352	2.6e-140	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HDDNOHNL_02353	1.17e-306	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
HDDNOHNL_02354	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HDDNOHNL_02355	2.59e-19	-	-	-	-	-	-	-	-
HDDNOHNL_02356	1.93e-31	plnF	-	-	-	-	-	-	-
HDDNOHNL_02357	8.15e-167	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HDDNOHNL_02358	1.17e-60	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HDDNOHNL_02359	6.27e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HDDNOHNL_02360	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HDDNOHNL_02361	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDDNOHNL_02362	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HDDNOHNL_02363	3.97e-229	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HDDNOHNL_02364	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HDDNOHNL_02365	4.71e-210	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HDDNOHNL_02366	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HDDNOHNL_02367	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HDDNOHNL_02368	1.63e-163	mleR	-	-	K	-	-	-	LysR substrate binding domain
HDDNOHNL_02369	5.44e-35	mleR	-	-	K	-	-	-	LysR substrate binding domain
HDDNOHNL_02370	0.0	-	-	-	M	-	-	-	domain protein
HDDNOHNL_02372	1.03e-201	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HDDNOHNL_02373	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HDDNOHNL_02374	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HDDNOHNL_02375	2.65e-102	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HDDNOHNL_02376	1.45e-278	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDDNOHNL_02377	1.24e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HDDNOHNL_02378	6.7e-148	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
HDDNOHNL_02379	3.38e-227	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HDDNOHNL_02380	6.33e-46	-	-	-	-	-	-	-	-
HDDNOHNL_02381	1.15e-79	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HDDNOHNL_02382	4.37e-208	fbpA	-	-	K	-	-	-	Domain of unknown function (DUF814)
HDDNOHNL_02383	1.29e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDDNOHNL_02384	3.81e-18	-	-	-	-	-	-	-	-
HDDNOHNL_02385	3.18e-77	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HDDNOHNL_02386	5.66e-74	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HDDNOHNL_02387	2.2e-280	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
HDDNOHNL_02388	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HDDNOHNL_02389	9.24e-140	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HDDNOHNL_02390	2.35e-106	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDDNOHNL_02391	2.64e-61	-	-	-	-	-	-	-	-
HDDNOHNL_02392	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HDDNOHNL_02393	1.31e-242	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HDDNOHNL_02394	3.45e-209	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HDDNOHNL_02395	6.83e-292	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HDDNOHNL_02396	6.08e-312	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HDDNOHNL_02397	1.53e-213	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HDDNOHNL_02398	9.31e-225	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HDDNOHNL_02399	6.03e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HDDNOHNL_02400	1.32e-178	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDDNOHNL_02401	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HDDNOHNL_02402	9.51e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
HDDNOHNL_02403	1.18e-175	yceF	-	-	P	ko:K05794	-	ko00000	membrane
HDDNOHNL_02404	2.47e-125	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HDDNOHNL_02405	1.9e-258	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HDDNOHNL_02406	1.07e-68	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
HDDNOHNL_02407	6.12e-78	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HDDNOHNL_02408	1.27e-172	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HDDNOHNL_02409	5.62e-165	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HDDNOHNL_02410	2.23e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HDDNOHNL_02411	2.46e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HDDNOHNL_02412	7.8e-299	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HDDNOHNL_02413	1.69e-151	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HDDNOHNL_02414	2.3e-275	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HDDNOHNL_02415	4.54e-208	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
HDDNOHNL_02416	3.72e-283	ysaA	-	-	V	-	-	-	RDD family
HDDNOHNL_02417	3.8e-126	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HDDNOHNL_02418	2.89e-312	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HDDNOHNL_02419	3.66e-189	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HDDNOHNL_02420	3.36e-216	-	-	-	K	-	-	-	LysR substrate binding domain
HDDNOHNL_02421	2.07e-302	-	-	-	EK	-	-	-	Aminotransferase, class I
HDDNOHNL_02422	2.13e-167	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HDDNOHNL_02423	2.11e-158	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDDNOHNL_02424	3.02e-176	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HDDNOHNL_02425	1.26e-161	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HDDNOHNL_02426	1.07e-127	-	-	-	KT	-	-	-	response to antibiotic
HDDNOHNL_02427	2.86e-68	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
HDDNOHNL_02428	1.73e-132	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HDDNOHNL_02429	1.6e-200	-	-	-	S	-	-	-	Putative adhesin
HDDNOHNL_02430	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDDNOHNL_02431	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HDDNOHNL_02432	1.06e-232	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HDDNOHNL_02433	3.73e-263	-	-	-	S	-	-	-	DUF218 domain
HDDNOHNL_02434	2.44e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HDDNOHNL_02435	2.93e-151	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDDNOHNL_02436	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDDNOHNL_02437	6.26e-101	-	-	-	-	-	-	-	-
HDDNOHNL_02438	2.69e-194	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
HDDNOHNL_02439	3.54e-190	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HDDNOHNL_02440	2.24e-116	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HDDNOHNL_02441	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
HDDNOHNL_02442	9.49e-155	fptC	-	-	U	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase system, EIIC
HDDNOHNL_02443	2.52e-35	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HDDNOHNL_02444	5.55e-22	-	-	-	G	ko:K11203	-	ko00000,ko00002,ko02000	PTS system, fructose subfamily
HDDNOHNL_02445	1.5e-104	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HDDNOHNL_02446	6.92e-206	yicL	-	-	EG	-	-	-	EamA-like transporter family
HDDNOHNL_02447	6.12e-166	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HDDNOHNL_02448	3.39e-225	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
HDDNOHNL_02449	5.93e-144	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HDDNOHNL_02450	5.07e-62	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HDDNOHNL_02451	3.06e-206	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HDDNOHNL_02452	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
HDDNOHNL_02453	9.86e-117	-	-	-	-	-	-	-	-
HDDNOHNL_02454	1.02e-164	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HDDNOHNL_02455	9.21e-234	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HDDNOHNL_02456	7.39e-121	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HDDNOHNL_02457	5.85e-204	ccpB	-	-	K	-	-	-	lacI family
HDDNOHNL_02458	2.21e-154	yceE	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HDDNOHNL_02459	8.08e-154	ydgI3	-	-	C	-	-	-	Nitroreductase family
HDDNOHNL_02460	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HDDNOHNL_02461	4.21e-150	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HDDNOHNL_02462	5.82e-198	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HDDNOHNL_02463	6.97e-216	XK27_00670	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HDDNOHNL_02464	0.0	-	-	-	-	-	-	-	-
HDDNOHNL_02465	4.71e-81	-	-	-	-	-	-	-	-
HDDNOHNL_02466	5.52e-242	-	-	-	S	-	-	-	Cell surface protein
HDDNOHNL_02467	1.27e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HDDNOHNL_02468	5.06e-82	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HDDNOHNL_02469	3.13e-42	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HDDNOHNL_02470	2.78e-158	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDDNOHNL_02471	5.21e-180	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
HDDNOHNL_02472	2.29e-193	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HDDNOHNL_02473	4.54e-191	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HDDNOHNL_02474	1.04e-269	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HDDNOHNL_02476	1.15e-43	-	-	-	-	-	-	-	-
HDDNOHNL_02477	2.1e-116	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HDDNOHNL_02478	1.06e-16	-	-	-	-	-	-	-	-
HDDNOHNL_02479	1.96e-21	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
HDDNOHNL_02480	0.0	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
HDDNOHNL_02481	1.32e-101	nrp	-	-	K	ko:K16509	-	ko00000	ArsC family
HDDNOHNL_02482	7.42e-174	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HDDNOHNL_02483	3.78e-212	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HDDNOHNL_02484	9.62e-19	-	-	-	-	-	-	-	-
HDDNOHNL_02485	1.51e-85	-	-	-	KOT	ko:K07813	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01002	May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
HDDNOHNL_02486	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
HDDNOHNL_02488	8.76e-72	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HDDNOHNL_02489	6.67e-165	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HDDNOHNL_02490	0.0	pox4	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HDDNOHNL_02491	5.03e-95	-	-	-	K	-	-	-	Transcriptional regulator
HDDNOHNL_02492	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HDDNOHNL_02493	6.96e-83	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HDDNOHNL_02494	5.88e-233	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
HDDNOHNL_02495	1.23e-129	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
HDDNOHNL_02496	3.33e-113	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
HDDNOHNL_02497	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HDDNOHNL_02498	1.56e-185	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
HDDNOHNL_02499	2.53e-209	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
HDDNOHNL_02500	2.03e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HDDNOHNL_02501	4.52e-209	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HDDNOHNL_02502	1.88e-240	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HDDNOHNL_02503	3.36e-06	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HDDNOHNL_02504	2.46e-08	-	-	-	-	-	-	-	-
HDDNOHNL_02505	1.23e-26	-	-	-	-	-	-	-	-
HDDNOHNL_02506	1.1e-147	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HDDNOHNL_02507	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDDNOHNL_02508	9.2e-317	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDDNOHNL_02509	2.09e-85	-	-	-	-	-	-	-	-
HDDNOHNL_02510	2.85e-83	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HDDNOHNL_02511	2.15e-281	-	-	-	S	-	-	-	Membrane
HDDNOHNL_02512	1.04e-59	-	-	-	S	-	-	-	Protein of unknown function (DUF3781)
HDDNOHNL_02513	1.31e-139	yoaZ	-	-	S	-	-	-	intracellular protease amidase
HDDNOHNL_02514	2.33e-56	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HDDNOHNL_02515	5.36e-76	-	-	-	-	-	-	-	-
HDDNOHNL_02516	1.46e-81	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HDDNOHNL_02517	5.31e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
HDDNOHNL_02518	3.17e-258	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HDDNOHNL_02519	2e-62	-	-	-	K	-	-	-	Helix-turn-helix domain
HDDNOHNL_02520	3.87e-115	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HDDNOHNL_02521	1.06e-72	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HDDNOHNL_02522	5.53e-114	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDDNOHNL_02523	6.79e-53	-	-	-	-	-	-	-	-
HDDNOHNL_02524	5.06e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HDDNOHNL_02525	1.6e-233	ydbI	-	-	K	-	-	-	AI-2E family transporter
HDDNOHNL_02526	9.28e-271	xylR	-	-	GK	-	-	-	ROK family
HDDNOHNL_02527	2.92e-143	-	-	-	-	-	-	-	-
HDDNOHNL_02528	3.66e-295	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HDDNOHNL_02529	3.32e-210	-	-	-	-	-	-	-	-
HDDNOHNL_02530	1.86e-256	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
HDDNOHNL_02531	9.58e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
HDDNOHNL_02532	2.47e-125	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HDDNOHNL_02533	9.69e-99	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HDDNOHNL_02534	5.6e-292	-	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
HDDNOHNL_02535	2.13e-159	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HDDNOHNL_02536	1.86e-210	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
HDDNOHNL_02537	1.33e-196	nanK	-	-	GK	-	-	-	ROK family
HDDNOHNL_02538	9.03e-173	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HDDNOHNL_02539	4.01e-263	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HDDNOHNL_02540	0.0	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HDDNOHNL_02541	3.89e-205	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HDDNOHNL_02542	3.21e-127	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HDDNOHNL_02543	8.16e-48	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HDDNOHNL_02544	6.47e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HDDNOHNL_02545	3.76e-180	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HDDNOHNL_02546	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HDDNOHNL_02547	1.83e-146	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
HDDNOHNL_02548	3.99e-106	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HDDNOHNL_02549	6e-60	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HDDNOHNL_02550	8.37e-296	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HDDNOHNL_02551	5.26e-247	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
HDDNOHNL_02552	9.14e-146	gph3	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HDDNOHNL_02553	0.0	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HDDNOHNL_02554	1.58e-101	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HDDNOHNL_02555	7.29e-61	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system galactitol-specific IIB component
HDDNOHNL_02556	1.17e-305	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HDDNOHNL_02557	1.68e-146	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HDDNOHNL_02558	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HDDNOHNL_02559	1.74e-184	yxeH	-	-	S	-	-	-	hydrolase
HDDNOHNL_02560	5.61e-39	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HDDNOHNL_02561	1.82e-34	-	-	-	S	-	-	-	Immunity protein 74
HDDNOHNL_02562	6.75e-85	-	-	-	M	-	-	-	dTDP-4-dehydrorhamnose reductase activity
HDDNOHNL_02563	0.0	-	-	-	M	-	-	-	domain protein
HDDNOHNL_02564	2.14e-174	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HDDNOHNL_02565	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
HDDNOHNL_02566	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HDDNOHNL_02567	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HDDNOHNL_02568	2.7e-230	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HDDNOHNL_02569	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HDDNOHNL_02570	4.06e-102	-	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
HDDNOHNL_02571	2.42e-207	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDDNOHNL_02572	1.49e-223	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HDDNOHNL_02573	2.32e-101	accB3	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HDDNOHNL_02574	2.16e-103	-	-	-	-	-	-	-	-
HDDNOHNL_02575	5.89e-108	-	-	-	K	-	-	-	Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HDDNOHNL_02576	1.54e-292	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HDDNOHNL_02577	1.31e-124	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HDDNOHNL_02578	5.34e-72	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HDDNOHNL_02579	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
HDDNOHNL_02580	8.36e-154	rpiA2	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HDDNOHNL_02581	1.99e-26	zmp1	-	-	O	-	-	-	Zinc-dependent metalloprotease
HDDNOHNL_02582	8.95e-60	-	-	-	-	-	-	-	-
HDDNOHNL_02583	1.05e-225	hicD1	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HDDNOHNL_02584	1.89e-169	-	-	-	S	-	-	-	KR domain
HDDNOHNL_02585	2.56e-83	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HDDNOHNL_02586	1.62e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF1905)
HDDNOHNL_02587	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HDDNOHNL_02588	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HDDNOHNL_02589	2.09e-213	-	-	-	GM	-	-	-	NmrA-like family
HDDNOHNL_02590	1.15e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDDNOHNL_02591	5.93e-281	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HDDNOHNL_02592	6.58e-173	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HDDNOHNL_02593	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HDDNOHNL_02594	7.81e-148	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HDDNOHNL_02595	5.78e-269	-	-	-	EGP	-	-	-	Major Facilitator
HDDNOHNL_02596	3.25e-81	ytcD	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HDDNOHNL_02597	1.06e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HDDNOHNL_02598	4.13e-157	-	-	-	-	-	-	-	-
HDDNOHNL_02599	8.09e-200	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HDDNOHNL_02600	1.47e-83	-	-	-	-	-	-	-	-
HDDNOHNL_02601	3.15e-130	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HDDNOHNL_02602	2.16e-241	ynjC	-	-	S	-	-	-	Cell surface protein
HDDNOHNL_02603	2.63e-146	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HDDNOHNL_02604	5.83e-87	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HDDNOHNL_02605	6.57e-226	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
HDDNOHNL_02606	2.56e-131	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HDDNOHNL_02607	8.07e-163	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HDDNOHNL_02608	6.36e-134	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HDDNOHNL_02609	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HDDNOHNL_02610	1.56e-108	-	-	-	-	-	-	-	-
HDDNOHNL_02611	5.97e-96	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HDDNOHNL_02612	9.2e-243	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HDDNOHNL_02613	7.3e-245	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HDDNOHNL_02614	3.7e-30	-	-	-	-	-	-	-	-
HDDNOHNL_02615	1.38e-131	-	-	-	-	-	-	-	-
HDDNOHNL_02616	3.46e-210	-	-	-	K	-	-	-	LysR substrate binding domain
HDDNOHNL_02617	4.34e-314	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HDDNOHNL_02618	0.0	-	4.1.1.98	-	H	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HDDNOHNL_02619	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HDDNOHNL_02620	1.37e-182	-	-	-	S	-	-	-	zinc-ribbon domain
HDDNOHNL_02622	4.29e-50	-	-	-	-	-	-	-	-
HDDNOHNL_02623	1.4e-137	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HDDNOHNL_02624	1.4e-20	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HDDNOHNL_02625	2.35e-231	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HDDNOHNL_02626	0.0	-	-	-	I	-	-	-	acetylesterase activity
HDDNOHNL_02627	6.08e-78	-	-	-	M	-	-	-	Collagen binding domain
HDDNOHNL_02645	1.08e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HDDNOHNL_02646	2.81e-178	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HDDNOHNL_02647	9.28e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HDDNOHNL_02648	7.12e-170	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HDDNOHNL_02649	1.64e-17	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HDDNOHNL_02650	1.52e-231	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HDDNOHNL_02651	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HDDNOHNL_02652	2.24e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
HDDNOHNL_02653	9.08e-157	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HDDNOHNL_02654	1.29e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HDDNOHNL_02655	6.31e-222	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HDDNOHNL_02656	7.21e-150	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HDDNOHNL_02657	1.6e-246	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HDDNOHNL_02658	2.68e-75	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HDDNOHNL_02659	9.52e-264	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
HDDNOHNL_02660	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HDDNOHNL_02661	1.12e-207	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HDDNOHNL_02663	3.59e-301	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HDDNOHNL_02664	2.5e-147	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HDDNOHNL_02665	1.19e-49	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HDDNOHNL_02666	2.71e-60	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HDDNOHNL_02667	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HDDNOHNL_02668	2.14e-183	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HDDNOHNL_02669	2.71e-234	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HDDNOHNL_02670	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HDDNOHNL_02671	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HDDNOHNL_02672	6.05e-98	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HDDNOHNL_02673	1.78e-279	-	-	-	M	-	-	-	domain protein
HDDNOHNL_02674	6.32e-67	-	-	-	M	-	-	-	domain protein
HDDNOHNL_02675	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HDDNOHNL_02676	1.06e-145	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HDDNOHNL_02677	1.45e-46	-	-	-	-	-	-	-	-
HDDNOHNL_02678	5.48e-236	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HDDNOHNL_02679	1.97e-254	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HDDNOHNL_02680	4.54e-126	-	-	-	J	-	-	-	glyoxalase III activity
HDDNOHNL_02681	1.01e-189	-	-	-	GM	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDDNOHNL_02682	4.73e-118	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
HDDNOHNL_02683	6.7e-74	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HDDNOHNL_02684	1.09e-54	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HDDNOHNL_02685	1.37e-92	-	-	-	M	-	-	-	LysM domain protein
HDDNOHNL_02686	4.2e-88	gcsH1	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Glycine cleavage H-protein
HDDNOHNL_02687	4.29e-227	-	-	-	-	-	-	-	-
HDDNOHNL_02688	3.27e-168	-	-	-	-	-	-	-	-
HDDNOHNL_02689	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
HDDNOHNL_02690	3.01e-75	-	-	-	-	-	-	-	-
HDDNOHNL_02691	3.74e-284	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDDNOHNL_02692	9.81e-33	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HDDNOHNL_02693	1.02e-98	-	-	-	K	-	-	-	Transcriptional regulator
HDDNOHNL_02694	9.59e-288	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HDDNOHNL_02695	2.18e-53	-	-	-	-	-	-	-	-
HDDNOHNL_02696	3.07e-264	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDDNOHNL_02697	1.31e-179	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDDNOHNL_02698	6.34e-190	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDDNOHNL_02699	8.8e-264	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HDDNOHNL_02700	3.68e-125	-	-	-	K	-	-	-	Cupin domain
HDDNOHNL_02701	8.08e-110	-	-	-	S	-	-	-	ASCH
HDDNOHNL_02702	1.88e-111	-	-	-	K	-	-	-	GNAT family
HDDNOHNL_02703	2.14e-117	-	-	-	K	-	-	-	acetyltransferase
HDDNOHNL_02704	2.06e-30	-	-	-	-	-	-	-	-
HDDNOHNL_02705	5.05e-79	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HDDNOHNL_02706	1.85e-208	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDDNOHNL_02707	1.08e-243	-	-	-	-	-	-	-	-
HDDNOHNL_02708	3.5e-307	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HDDNOHNL_02709	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
HDDNOHNL_02710	4.63e-119	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HDDNOHNL_02711	3.93e-59	-	-	-	-	-	-	-	-
HDDNOHNL_02712	9.42e-258	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HDDNOHNL_02713	1.15e-198	tagG	-	-	U	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HDDNOHNL_02714	1.57e-280	-	-	-	-	-	-	-	-
HDDNOHNL_02715	3.51e-281	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HDDNOHNL_02716	3.08e-81	-	-	-	S	-	-	-	CHY zinc finger
HDDNOHNL_02717	6.8e-224	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HDDNOHNL_02718	7.31e-122	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HDDNOHNL_02719	6.4e-54	-	-	-	-	-	-	-	-
HDDNOHNL_02720	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HDDNOHNL_02721	3.48e-40	-	-	-	-	-	-	-	-
HDDNOHNL_02722	5.81e-170	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HDDNOHNL_02723	2.75e-304	xylP1	-	-	G	-	-	-	MFS/sugar transport protein
HDDNOHNL_02725	8.16e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HDDNOHNL_02726	0.0	acdH	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
HDDNOHNL_02727	2.07e-40	-	-	-	-	-	-	-	-
HDDNOHNL_02728	7.92e-140	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HDDNOHNL_02729	5.93e-73	-	-	-	S	-	-	-	branched-chain amino acid
HDDNOHNL_02730	2.05e-167	-	-	-	E	-	-	-	branched-chain amino acid
HDDNOHNL_02731	1.6e-114	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HDDNOHNL_02732	3.1e-304	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HDDNOHNL_02733	5.61e-273	hpk31	-	-	T	-	-	-	Histidine kinase
HDDNOHNL_02734	1.14e-159	vanR	-	-	K	-	-	-	response regulator
HDDNOHNL_02735	2.4e-161	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HDDNOHNL_02736	3.3e-208	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HDDNOHNL_02737	1.42e-269	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HDDNOHNL_02738	3.49e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HDDNOHNL_02739	6.6e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HDDNOHNL_02740	1.4e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HDDNOHNL_02741	7.16e-201	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HDDNOHNL_02742	1.01e-175	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HDDNOHNL_02743	8.63e-191	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HDDNOHNL_02744	1.81e-168	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HDDNOHNL_02745	4.76e-288	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
HDDNOHNL_02746	2.87e-270	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HDDNOHNL_02747	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HDDNOHNL_02748	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HDDNOHNL_02749	2.5e-90	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HDDNOHNL_02750	6.46e-221	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
HDDNOHNL_02751	1.04e-98	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HDDNOHNL_02753	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HDDNOHNL_02754	1.53e-26	-	-	-	-	-	-	-	-
HDDNOHNL_02755	4.95e-103	-	-	-	-	-	-	-	-
HDDNOHNL_02757	3.8e-25	-	-	-	-	-	-	-	-
HDDNOHNL_02758	1.32e-224	-	-	-	M	-	-	-	Peptidase family S41
HDDNOHNL_02759	7.34e-124	-	-	-	K	-	-	-	Helix-turn-helix domain
HDDNOHNL_02760	5.05e-05	-	-	-	S	-	-	-	FRG
HDDNOHNL_02761	7.19e-89	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HDDNOHNL_02762	6.88e-152	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDDNOHNL_02763	0.0	lepA2	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HDDNOHNL_02764	0.0	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HDDNOHNL_02765	1.85e-201	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
HDDNOHNL_02766	4.33e-205	-	-	-	K	-	-	-	LysR substrate binding domain
HDDNOHNL_02767	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HDDNOHNL_02768	0.0	-	-	-	S	-	-	-	MucBP domain
HDDNOHNL_02769	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
HDDNOHNL_02770	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HDDNOHNL_02771	2.44e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HDDNOHNL_02772	0.0	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
HDDNOHNL_02773	2.91e-190	malA	-	-	S	-	-	-	maltodextrose utilization protein MalA
HDDNOHNL_02774	2.83e-206	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDDNOHNL_02775	3.74e-302	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDDNOHNL_02776	9.45e-299	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HDDNOHNL_02777	3.39e-52	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HDDNOHNL_02778	1.71e-59	-	-	-	S	-	-	-	MORN repeat
HDDNOHNL_02779	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase family
HDDNOHNL_02780	1.81e-50	ydaS	-	-	S	-	-	-	Transglycosylase associated protein
HDDNOHNL_02781	1.37e-116	-	-	-	-	-	-	-	-
HDDNOHNL_02782	5.74e-32	-	-	-	-	-	-	-	-
HDDNOHNL_02783	1.1e-93	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HDDNOHNL_02784	1.04e-94	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HDDNOHNL_02785	2.02e-192	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
HDDNOHNL_02786	6.72e-208	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HDDNOHNL_02787	5.6e-14	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HDDNOHNL_02788	2.66e-132	-	-	-	G	-	-	-	Glycogen debranching enzyme
HDDNOHNL_02789	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HDDNOHNL_02790	3.26e-102	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HDDNOHNL_02791	5.3e-157	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HDDNOHNL_02792	4.29e-101	-	-	-	-	-	-	-	-
HDDNOHNL_02793	5.09e-51	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HDDNOHNL_02794	2.42e-127	-	-	-	FG	-	-	-	HIT domain
HDDNOHNL_02795	4.27e-223	ydhF	-	-	S	-	-	-	Aldo keto reductase
HDDNOHNL_02796	5.17e-70	-	-	-	S	-	-	-	Pfam:DUF59
HDDNOHNL_02797	4.56e-206	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HDDNOHNL_02798	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HDDNOHNL_02799	1.87e-249	-	-	-	V	-	-	-	Beta-lactamase
HDDNOHNL_02800	3.74e-125	-	-	-	V	-	-	-	VanZ like family
HDDNOHNL_02801	2.81e-181	-	-	-	K	-	-	-	Helix-turn-helix domain
HDDNOHNL_02802	2.97e-51	-	-	-	S	ko:K07343	-	ko00000	TfoX C-terminal domain
HDDNOHNL_02803	3.56e-288	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HDDNOHNL_02804	0.0	-	-	-	-	-	-	-	-
HDDNOHNL_02805	3.15e-98	-	-	-	-	-	-	-	-
HDDNOHNL_02806	7.81e-241	-	-	-	S	-	-	-	Cell surface protein
HDDNOHNL_02807	6.02e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HDDNOHNL_02808	4.31e-179	-	-	-	-	-	-	-	-
HDDNOHNL_02809	2.82e-236	-	-	-	S	-	-	-	DUF218 domain
HDDNOHNL_02810	3.26e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HDDNOHNL_02811	9.06e-193	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HDDNOHNL_02812	5.78e-292	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HDDNOHNL_02813	1.96e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HDDNOHNL_02814	5.3e-49	-	-	-	-	-	-	-	-
HDDNOHNL_02815	2.95e-57	-	-	-	S	-	-	-	ankyrin repeats
HDDNOHNL_02816	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HDDNOHNL_02817	3.1e-172	repA	-	-	S	-	-	-	Replication initiator protein A
HDDNOHNL_02818	1.95e-25	-	-	-	-	-	-	-	-
HDDNOHNL_02819	6.52e-52	-	-	-	S	-	-	-	protein conserved in bacteria
HDDNOHNL_02820	4.93e-54	-	-	-	-	-	-	-	-
HDDNOHNL_02821	1.39e-36	-	-	-	-	-	-	-	-
HDDNOHNL_02822	1.26e-248	-	-	-	L	-	-	-	MobA MobL family protein
HDDNOHNL_02823	2.28e-211	traA	-	-	L	-	-	-	MobA MobL family protein
HDDNOHNL_02824	5.07e-155	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HDDNOHNL_02826	6.34e-39	-	-	-	-	-	-	-	-
HDDNOHNL_02827	1.4e-13	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HDDNOHNL_02828	7.1e-81	-	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HDDNOHNL_02829	9.04e-78	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
HDDNOHNL_02830	1.11e-59	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HDDNOHNL_02831	1.26e-137	-	-	-	L	-	-	-	Integrase
HDDNOHNL_02832	2.08e-60	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
HDDNOHNL_02833	3.03e-49	-	-	-	K	-	-	-	sequence-specific DNA binding
HDDNOHNL_02834	9.13e-70	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
HDDNOHNL_02835	2.78e-231	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
HDDNOHNL_02836	1.98e-72	repA	-	-	S	-	-	-	Replication initiator protein A
HDDNOHNL_02837	1.32e-57	-	-	-	-	-	-	-	-
HDDNOHNL_02838	1.76e-214	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HDDNOHNL_02839	5.13e-119	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HDDNOHNL_02840	7.59e-64	-	-	-	-	-	-	-	-
HDDNOHNL_02841	6.83e-274	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
HDDNOHNL_02842	8.05e-178	-	-	-	F	-	-	-	NUDIX domain
HDDNOHNL_02843	2.68e-32	-	-	-	-	-	-	-	-
HDDNOHNL_02845	8.51e-209	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HDDNOHNL_02846	1.23e-222	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
HDDNOHNL_02847	3.43e-106	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
HDDNOHNL_02848	2.29e-48	-	-	-	-	-	-	-	-
HDDNOHNL_02849	4.54e-45	-	-	-	-	-	-	-	-
HDDNOHNL_02850	9.39e-277	-	-	-	T	-	-	-	diguanylate cyclase
HDDNOHNL_02852	2.55e-218	-	-	-	EG	-	-	-	EamA-like transporter family
HDDNOHNL_02853	1.06e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HDDNOHNL_02854	2.12e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HDDNOHNL_02855	1.45e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HDDNOHNL_02856	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HDDNOHNL_02857	5.23e-277	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HDDNOHNL_02858	2.51e-200	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HDDNOHNL_02860	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
HDDNOHNL_02861	1.03e-77	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HDDNOHNL_02862	4.17e-55	-	-	-	K	-	-	-	prlF antitoxin for toxin YhaV_toxin
HDDNOHNL_02863	1.87e-139	-	-	-	L	-	-	-	Integrase
HDDNOHNL_02864	3.67e-41	-	-	-	-	-	-	-	-
HDDNOHNL_02865	2.29e-225	-	-	-	L	-	-	-	Initiator Replication protein
HDDNOHNL_02866	6.66e-115	-	-	-	-	-	-	-	-
HDDNOHNL_02867	1.74e-18	-	-	-	Q	-	-	-	Methyltransferase
HDDNOHNL_02868	6.04e-43	-	-	-	-	-	-	-	-
HDDNOHNL_02869	4.67e-35	-	-	-	-	-	-	-	-
HDDNOHNL_02870	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
HDDNOHNL_02871	0.0	merA	1.16.1.1	-	C	ko:K00520,ko:K21739	-	ko00000,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HDDNOHNL_02872	1.29e-80	-	-	-	M	-	-	-	Cna protein B-type domain
HDDNOHNL_02873	1.95e-139	pbg9	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDDNOHNL_02874	6.87e-204	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HDDNOHNL_02875	6.16e-298	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
HDDNOHNL_02876	4.73e-206	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HDDNOHNL_02877	2.13e-167	-	-	-	L	-	-	-	Helix-turn-helix domain
HDDNOHNL_02878	1.07e-74	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HDDNOHNL_02879	9.51e-142	XK27_07075	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HDDNOHNL_02881	1.92e-18	mpr	-	-	E	-	-	-	Trypsin-like serine protease
HDDNOHNL_02882	3.53e-38	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDDNOHNL_02885	1.61e-74	mleR	-	-	K	-	-	-	LysR substrate binding domain
HDDNOHNL_02886	3.55e-169	-	-	-	K	-	-	-	LysR family
HDDNOHNL_02887	0.0	-	-	-	C	-	-	-	FMN_bind
HDDNOHNL_02888	2.17e-304	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HDDNOHNL_02889	3.99e-101	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HDDNOHNL_02891	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HDDNOHNL_02892	2.51e-103	-	-	-	T	-	-	-	Universal stress protein family
HDDNOHNL_02893	7.43e-130	padR	-	-	K	-	-	-	Virulence activator alpha C-term
HDDNOHNL_02894	3.71e-36	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HDDNOHNL_02895	7.39e-83	-	-	-	G	-	-	-	COG0662 Mannose-6-phosphate isomerase
HDDNOHNL_02896	2.85e-57	-	-	-	-	-	-	-	-
HDDNOHNL_02897	2.06e-66	ykoF	-	-	S	-	-	-	YKOF-related Family
HDDNOHNL_02898	5.63e-15	-	-	-	E	-	-	-	glutamine synthetase
HDDNOHNL_02899	9.73e-245	-	-	-	E	-	-	-	glutamine synthetase
HDDNOHNL_02900	0.0	-	-	-	L	-	-	-	MobA MobL family protein
HDDNOHNL_02901	2.09e-151	-	-	-	-	-	-	-	-
HDDNOHNL_02902	1.16e-84	-	-	-	-	-	-	-	-
HDDNOHNL_02903	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HDDNOHNL_02904	1.48e-81	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDDNOHNL_02905	5.32e-298	aspD	4.1.1.12	-	E	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	ko00000,ko00001,ko01000	Aminotransferase class I and II
HDDNOHNL_02906	9.33e-249	-	-	-	U	ko:K07085	-	ko00000	Predicted Permease Membrane Region
HDDNOHNL_02907	1.76e-71	-	-	-	L	-	-	-	Transposase DDE domain
HDDNOHNL_02908	5.17e-70	-	-	-	S	-	-	-	Nitroreductase
HDDNOHNL_02909	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HDDNOHNL_02910	4.21e-174	bgaR	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HDDNOHNL_02911	7.86e-68	-	-	-	L	-	-	-	Transposase IS66 family
HDDNOHNL_02912	2.89e-256	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HDDNOHNL_02913	3.9e-34	-	-	-	-	-	-	-	-
HDDNOHNL_02914	5.03e-75	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
HDDNOHNL_02915	4.16e-06	-	-	-	S	-	-	-	Transposase C of IS166 homeodomain
HDDNOHNL_02916	1.89e-71	-	-	-	-	-	-	-	-
HDDNOHNL_02917	2.44e-303	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HDDNOHNL_02918	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
HDDNOHNL_02919	8.86e-35	-	-	-	-	-	-	-	-
HDDNOHNL_02920	6.47e-10	-	-	-	P	-	-	-	Cation efflux family
HDDNOHNL_02921	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HDDNOHNL_02924	8.69e-185	-	-	-	D	-	-	-	AAA domain
HDDNOHNL_02925	4.87e-45	-	-	-	-	-	-	-	-
HDDNOHNL_02928	1.74e-72	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDDNOHNL_02929	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HDDNOHNL_02930	5.62e-49	kdpE	-	-	KT	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HDDNOHNL_02931	3.79e-26	-	-	-	-	-	-	-	-
HDDNOHNL_02932	2.64e-233	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HDDNOHNL_02933	5.41e-89	-	-	-	C	-	-	-	lyase activity
HDDNOHNL_02934	8.61e-19	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	adenosylhomocysteinase activity
HDDNOHNL_02935	1.62e-150	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HDDNOHNL_02936	3.77e-278	-	-	-	EGP	-	-	-	Major Facilitator
HDDNOHNL_02937	7.57e-122	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDDNOHNL_02938	3.47e-244	-	1.1.1.219	-	GM	ko:K00091	-	ko00000,ko01000	Male sterility protein
HDDNOHNL_02939	1.27e-129	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HDDNOHNL_02941	2.37e-49	-	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
HDDNOHNL_02943	1.19e-124	-	-	-	L	-	-	-	Resolvase, N terminal domain
HDDNOHNL_02944	7.8e-75	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
HDDNOHNL_02945	2.27e-129	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HDDNOHNL_02946	1.34e-34	-	-	-	-	-	-	-	-
HDDNOHNL_02947	8.5e-55	-	-	-	-	-	-	-	-
HDDNOHNL_02948	6.45e-111	-	-	-	-	-	-	-	-
HDDNOHNL_02949	2.83e-58	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
HDDNOHNL_02950	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HDDNOHNL_02952	1.15e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase
HDDNOHNL_02953	9.4e-122	-	-	-	L	-	-	-	4.5 Transposon and IS
HDDNOHNL_02955	5.15e-174	-	-	-	L	-	-	-	Replication protein
HDDNOHNL_02956	3.11e-17	-	-	-	S	-	-	-	protein with an alpha beta hydrolase fold
HDDNOHNL_02957	6.03e-36	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDDNOHNL_02958	5.43e-167	-	-	-	S	-	-	-	Phage Mu protein F like protein
HDDNOHNL_02959	3.62e-22	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
HDDNOHNL_02961	6.13e-127	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
HDDNOHNL_02962	1.18e-184	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
HDDNOHNL_02963	2.03e-31	-	-	-	S	-	-	-	Family of unknown function (DUF5388)
HDDNOHNL_02964	1.18e-194	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HDDNOHNL_02965	1.18e-192	degV	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HDDNOHNL_02966	1.39e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HDDNOHNL_02967	5.21e-165	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HDDNOHNL_02968	1.41e-163	-	-	-	P	-	-	-	integral membrane protein, YkoY family
HDDNOHNL_02970	3.47e-47	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
HDDNOHNL_02971	2.82e-205	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HDDNOHNL_02972	4.05e-211	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HDDNOHNL_02973	2.43e-91	-	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
HDDNOHNL_02974	3.55e-76	-	-	-	-	-	-	-	-
HDDNOHNL_02975	6.01e-49	-	-	-	S	-	-	-	Bacteriophage holin
HDDNOHNL_02976	2.58e-147	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HDDNOHNL_02977	8.81e-48	-	-	-	L	-	-	-	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HDDNOHNL_02980	3.24e-61	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
HDDNOHNL_02982	1.36e-54	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family