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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
DEMHKHKO_00001	1.66e-101	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DEMHKHKO_00002	3.46e-267	mccF	-	-	V	-	-	-	LD-carboxypeptidase
DEMHKHKO_00003	9.63e-307	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
DEMHKHKO_00004	9.19e-95	-	-	-	S	-	-	-	SnoaL-like domain
DEMHKHKO_00005	4.17e-186	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
DEMHKHKO_00006	1.55e-309	-	-	-	P	-	-	-	Major Facilitator Superfamily
DEMHKHKO_00007	1.26e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
DEMHKHKO_00008	1.44e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
DEMHKHKO_00010	9.98e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
DEMHKHKO_00011	2.12e-142	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
DEMHKHKO_00012	3.6e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
DEMHKHKO_00013	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
DEMHKHKO_00014	4.64e-228	phnT	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
DEMHKHKO_00015	8.06e-234	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
DEMHKHKO_00016	0.0	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DEMHKHKO_00017	5.32e-109	-	-	-	T	-	-	-	Universal stress protein family
DEMHKHKO_00018	1.58e-203	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
DEMHKHKO_00019	2.45e-142	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DEMHKHKO_00020	2.32e-238	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DEMHKHKO_00022	9.32e-165	dnaD	-	-	L	ko:K02086	-	ko00000	Replication initiation and membrane attachment
DEMHKHKO_00023	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
DEMHKHKO_00024	3.1e-289	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
DEMHKHKO_00025	2.53e-107	ypmB	-	-	S	-	-	-	protein conserved in bacteria
DEMHKHKO_00026	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
DEMHKHKO_00027	1.48e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
DEMHKHKO_00028	1.1e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
DEMHKHKO_00029	2.94e-261	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
DEMHKHKO_00030	8.61e-251	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
DEMHKHKO_00031	3.36e-247	galM2	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
DEMHKHKO_00032	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
DEMHKHKO_00033	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
DEMHKHKO_00034	3.24e-155	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
DEMHKHKO_00035	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
DEMHKHKO_00036	3.86e-192	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
DEMHKHKO_00037	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
DEMHKHKO_00038	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DEMHKHKO_00039	3.23e-58	-	-	-	-	-	-	-	-
DEMHKHKO_00040	1.25e-66	-	-	-	-	-	-	-	-
DEMHKHKO_00041	5.03e-182	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
DEMHKHKO_00042	1.48e-218	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
DEMHKHKO_00043	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
DEMHKHKO_00044	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
DEMHKHKO_00045	1.06e-53	-	-	-	-	-	-	-	-
DEMHKHKO_00046	4e-40	-	-	-	S	-	-	-	CsbD-like
DEMHKHKO_00047	2.22e-55	-	-	-	S	-	-	-	transglycosylase associated protein
DEMHKHKO_00048	5.79e-21	-	-	-	-	-	-	-	-
DEMHKHKO_00049	8.76e-48	-	-	-	-	-	-	-	-
DEMHKHKO_00050	1.21e-209	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
DEMHKHKO_00051	5.58e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
DEMHKHKO_00052	5.28e-100	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
DEMHKHKO_00053	6.05e-108	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
DEMHKHKO_00054	2.05e-55	-	-	-	-	-	-	-	-
DEMHKHKO_00055	5.93e-60	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
DEMHKHKO_00056	9.96e-147	-	1.14.99.53	AA10	S	ko:K21713	-	ko00000,ko01000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
DEMHKHKO_00057	3.2e-37	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
DEMHKHKO_00058	6.57e-274	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
DEMHKHKO_00059	2.02e-39	-	-	-	-	-	-	-	-
DEMHKHKO_00060	1.48e-71	-	-	-	-	-	-	-	-
DEMHKHKO_00061	1.14e-193	-	-	-	O	-	-	-	Band 7 protein
DEMHKHKO_00062	0.0	-	-	-	EGP	-	-	-	Major Facilitator
DEMHKHKO_00063	4.09e-119	-	-	-	K	-	-	-	transcriptional regulator
DEMHKHKO_00064	4.4e-246	rsgA_2	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
DEMHKHKO_00065	2.01e-113	ykhA	-	-	I	-	-	-	Thioesterase superfamily
DEMHKHKO_00066	1.48e-161	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
DEMHKHKO_00067	5.01e-129	-	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
DEMHKHKO_00068	2.29e-175	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
DEMHKHKO_00069	4.82e-179	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
DEMHKHKO_00070	6.43e-203	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DEMHKHKO_00071	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
DEMHKHKO_00072	1.71e-91	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
DEMHKHKO_00073	2.14e-95	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
DEMHKHKO_00074	1.8e-288	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
DEMHKHKO_00075	1.26e-162	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
DEMHKHKO_00076	3.47e-215	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
DEMHKHKO_00077	6.16e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DEMHKHKO_00078	1.62e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DEMHKHKO_00079	8.55e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
DEMHKHKO_00080	1.62e-229	yneE	-	-	K	-	-	-	Transcriptional regulator
DEMHKHKO_00081	6.84e-186	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
DEMHKHKO_00083	1.49e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
DEMHKHKO_00084	2.69e-252	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
DEMHKHKO_00085	3.38e-274	hipO1	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	Peptidase family M20/M25/M40
DEMHKHKO_00086	1.62e-276	-	-	-	E	-	-	-	glutamate:sodium symporter activity
DEMHKHKO_00087	1.95e-88	ybbJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
DEMHKHKO_00088	1.36e-210	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
DEMHKHKO_00089	5.89e-126	entB	-	-	Q	-	-	-	Isochorismatase family
DEMHKHKO_00090	4.82e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
DEMHKHKO_00091	5.13e-287	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DEMHKHKO_00092	1.57e-142	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
DEMHKHKO_00093	2.41e-165	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
DEMHKHKO_00094	6.03e-226	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DEMHKHKO_00095	8.08e-135	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
DEMHKHKO_00096	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
DEMHKHKO_00098	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
DEMHKHKO_00099	2.05e-179	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
DEMHKHKO_00100	9.06e-112	-	-	-	-	-	-	-	-
DEMHKHKO_00101	2.81e-194	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
DEMHKHKO_00102	3.2e-70	-	-	-	-	-	-	-	-
DEMHKHKO_00103	3.15e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
DEMHKHKO_00104	1.57e-179	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
DEMHKHKO_00105	6.42e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DEMHKHKO_00106	9.99e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
DEMHKHKO_00107	1.6e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
DEMHKHKO_00108	7.69e-300	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DEMHKHKO_00109	1.46e-77	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DEMHKHKO_00110	2.85e-293	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DEMHKHKO_00111	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
DEMHKHKO_00112	4.49e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DEMHKHKO_00113	3.33e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DEMHKHKO_00114	2.17e-244	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
DEMHKHKO_00115	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DEMHKHKO_00116	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
DEMHKHKO_00117	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
DEMHKHKO_00118	1.61e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
DEMHKHKO_00119	1.84e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
DEMHKHKO_00120	3.16e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
DEMHKHKO_00121	1.21e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
DEMHKHKO_00122	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
DEMHKHKO_00123	1.62e-173	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
DEMHKHKO_00124	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DEMHKHKO_00125	1.01e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DEMHKHKO_00126	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DEMHKHKO_00127	1.02e-277	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DEMHKHKO_00128	3.93e-41	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
DEMHKHKO_00129	6.96e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
DEMHKHKO_00130	8.28e-73	-	-	-	-	-	-	-	-
DEMHKHKO_00131	1.36e-136	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DEMHKHKO_00132	3.8e-224	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
DEMHKHKO_00133	7.11e-135	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DEMHKHKO_00134	4.51e-284	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
DEMHKHKO_00135	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
DEMHKHKO_00136	2.15e-99	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
DEMHKHKO_00137	4.49e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
DEMHKHKO_00138	7.16e-201	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
DEMHKHKO_00139	7.55e-44	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DEMHKHKO_00140	3.28e-312	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DEMHKHKO_00141	4.82e-194	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DEMHKHKO_00142	2.82e-91	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DEMHKHKO_00143	1.7e-96	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
DEMHKHKO_00144	1.43e-129	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DEMHKHKO_00145	4.08e-247	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
DEMHKHKO_00146	2.33e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
DEMHKHKO_00147	7.97e-71	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
DEMHKHKO_00148	1.55e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
DEMHKHKO_00149	8.15e-125	-	-	-	K	-	-	-	Transcriptional regulator
DEMHKHKO_00150	9.81e-27	-	-	-	-	-	-	-	-
DEMHKHKO_00153	2.97e-41	-	-	-	-	-	-	-	-
DEMHKHKO_00154	3.11e-73	-	-	-	-	-	-	-	-
DEMHKHKO_00155	2.92e-126	-	-	-	S	-	-	-	Protein conserved in bacteria
DEMHKHKO_00156	1.34e-232	-	-	-	-	-	-	-	-
DEMHKHKO_00157	5.08e-205	-	-	-	-	-	-	-	-
DEMHKHKO_00158	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
DEMHKHKO_00159	7.79e-85	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
DEMHKHKO_00160	3.8e-224	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DEMHKHKO_00161	7.77e-179	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
DEMHKHKO_00162	1.44e-31	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
DEMHKHKO_00163	1.15e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
DEMHKHKO_00164	1.62e-141	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
DEMHKHKO_00165	2.6e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
DEMHKHKO_00166	6.33e-46	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
DEMHKHKO_00167	3.52e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
DEMHKHKO_00168	9.29e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DEMHKHKO_00169	5.33e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
DEMHKHKO_00170	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
DEMHKHKO_00171	0.0	-	-	-	S	-	-	-	membrane
DEMHKHKO_00172	6.12e-72	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
DEMHKHKO_00173	5.72e-99	-	-	-	K	-	-	-	LytTr DNA-binding domain
DEMHKHKO_00174	9.72e-146	-	-	-	S	-	-	-	membrane
DEMHKHKO_00175	1.09e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DEMHKHKO_00176	7.5e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
DEMHKHKO_00177	6.11e-249	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DEMHKHKO_00178	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DEMHKHKO_00179	6.88e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DEMHKHKO_00180	2.58e-82	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
DEMHKHKO_00181	1.72e-120	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
DEMHKHKO_00182	4.46e-179	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DEMHKHKO_00183	1.37e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
DEMHKHKO_00184	6.94e-209	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DEMHKHKO_00185	4.18e-121	-	-	-	S	-	-	-	SdpI/YhfL protein family
DEMHKHKO_00186	1.36e-288	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
DEMHKHKO_00187	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
DEMHKHKO_00188	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
DEMHKHKO_00189	1.38e-155	csrR	-	-	K	-	-	-	response regulator
DEMHKHKO_00190	2.56e-310	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
DEMHKHKO_00191	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DEMHKHKO_00192	1.09e-223	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DEMHKHKO_00193	3.06e-124	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
DEMHKHKO_00194	3.66e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
DEMHKHKO_00195	3.04e-280	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
DEMHKHKO_00196	3.3e-180	yqeM	-	-	Q	-	-	-	Methyltransferase
DEMHKHKO_00197	1.06e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
DEMHKHKO_00198	1.71e-149	yqeK	-	-	H	-	-	-	Hydrolase, HD family
DEMHKHKO_00199	4.19e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DEMHKHKO_00200	2.19e-67	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
DEMHKHKO_00201	3.81e-276	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
DEMHKHKO_00202	5.7e-127	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
DEMHKHKO_00203	6.32e-114	-	-	-	-	-	-	-	-
DEMHKHKO_00204	2.27e-297	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
DEMHKHKO_00205	3.97e-174	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
DEMHKHKO_00206	1.64e-83	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
DEMHKHKO_00207	1.18e-250	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
DEMHKHKO_00208	7.03e-307	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
DEMHKHKO_00209	4.59e-73	-	-	-	-	-	-	-	-
DEMHKHKO_00210	6.88e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DEMHKHKO_00211	6.92e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
DEMHKHKO_00212	2.37e-109	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DEMHKHKO_00213	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DEMHKHKO_00214	3.5e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
DEMHKHKO_00215	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
DEMHKHKO_00216	1.58e-117	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DEMHKHKO_00217	1.92e-133	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DEMHKHKO_00218	3.19e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
DEMHKHKO_00219	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DEMHKHKO_00220	8.51e-155	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
DEMHKHKO_00221	1.04e-141	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
DEMHKHKO_00222	4.07e-60	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
DEMHKHKO_00223	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
DEMHKHKO_00224	2.71e-108	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
DEMHKHKO_00225	1.11e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DEMHKHKO_00226	5.21e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
DEMHKHKO_00227	1.1e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
DEMHKHKO_00228	2.87e-47	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
DEMHKHKO_00229	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
DEMHKHKO_00230	3.04e-29	-	-	-	S	-	-	-	Virus attachment protein p12 family
DEMHKHKO_00231	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
DEMHKHKO_00232	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
DEMHKHKO_00233	1.29e-148	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DEMHKHKO_00234	2.94e-71	ytzB	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
DEMHKHKO_00235	2.8e-155	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
DEMHKHKO_00236	7.24e-197	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
DEMHKHKO_00237	8.17e-285	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
DEMHKHKO_00238	1.1e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DEMHKHKO_00239	3.6e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
DEMHKHKO_00240	6.76e-73	-	-	-	-	-	-	-	-
DEMHKHKO_00241	1.09e-196	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
DEMHKHKO_00242	1.78e-153	draG	-	-	O	-	-	-	ADP-ribosylglycohydrolase
DEMHKHKO_00243	5.76e-135	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
DEMHKHKO_00244	2.82e-138	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
DEMHKHKO_00245	1.94e-247	-	-	-	S	-	-	-	Fn3-like domain
DEMHKHKO_00246	1.65e-80	-	-	-	-	-	-	-	-
DEMHKHKO_00247	0.0	-	-	-	-	-	-	-	-
DEMHKHKO_00248	4.26e-308	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
DEMHKHKO_00250	2.16e-208	-	-	-	K	-	-	-	Transcriptional regulator
DEMHKHKO_00251	2.43e-206	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
DEMHKHKO_00252	1.66e-211	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
DEMHKHKO_00253	5.73e-100	-	-	-	K	-	-	-	Winged helix DNA-binding domain
DEMHKHKO_00254	0.0	ycaM	-	-	E	-	-	-	amino acid
DEMHKHKO_00255	2.38e-164	aroC1	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
DEMHKHKO_00256	4.3e-44	-	-	-	-	-	-	-	-
DEMHKHKO_00257	0.0	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
DEMHKHKO_00258	9.78e-187	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
DEMHKHKO_00259	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
DEMHKHKO_00260	4.75e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
DEMHKHKO_00261	0.0	-	-	-	-	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	-
DEMHKHKO_00262	1.54e-131	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
DEMHKHKO_00263	1.96e-224	serA1	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
DEMHKHKO_00264	3.98e-204	-	-	-	EG	-	-	-	EamA-like transporter family
DEMHKHKO_00265	6.86e-232	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DEMHKHKO_00266	5.06e-196	-	-	-	S	-	-	-	hydrolase
DEMHKHKO_00267	7.63e-107	-	-	-	-	-	-	-	-
DEMHKHKO_00268	1.75e-156	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
DEMHKHKO_00269	1.4e-181	epsV	-	-	S	-	-	-	glycosyl transferase family 2
DEMHKHKO_00270	1.23e-166	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
DEMHKHKO_00271	1.86e-64	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DEMHKHKO_00272	6.7e-74	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
DEMHKHKO_00273	0.0	pbg5	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DEMHKHKO_00274	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DEMHKHKO_00275	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
DEMHKHKO_00276	4.29e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
DEMHKHKO_00277	9.24e-231	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
DEMHKHKO_00278	6.09e-152	-	-	-	K	-	-	-	Transcriptional regulator
DEMHKHKO_00279	5.71e-159	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DEMHKHKO_00280	7.54e-115	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
DEMHKHKO_00281	4.43e-294	-	-	-	S	-	-	-	Sterol carrier protein domain
DEMHKHKO_00282	2.45e-269	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
DEMHKHKO_00283	3.25e-48	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
DEMHKHKO_00284	5.41e-172	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
DEMHKHKO_00285	2.26e-91	-	-	-	FG	-	-	-	Scavenger mRNA decapping enzyme C-term binding
DEMHKHKO_00286	1.13e-132	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
DEMHKHKO_00287	5.88e-142	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
DEMHKHKO_00288	2.99e-38	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
DEMHKHKO_00289	4.65e-186	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
DEMHKHKO_00290	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
DEMHKHKO_00291	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
DEMHKHKO_00293	1.21e-69	-	-	-	-	-	-	-	-
DEMHKHKO_00294	1.52e-151	-	-	-	-	-	-	-	-
DEMHKHKO_00295	1.16e-110	-	-	-	F	-	-	-	belongs to the nudix hydrolase family
DEMHKHKO_00296	3.03e-299	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
DEMHKHKO_00297	4.79e-13	-	-	-	-	-	-	-	-
DEMHKHKO_00298	5.92e-67	-	-	-	-	-	-	-	-
DEMHKHKO_00299	1.76e-114	-	-	-	-	-	-	-	-
DEMHKHKO_00300	5.7e-95	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
DEMHKHKO_00301	3.64e-46	-	-	-	-	-	-	-	-
DEMHKHKO_00302	1.1e-103	usp5	-	-	T	-	-	-	universal stress protein
DEMHKHKO_00303	4.21e-175	-	-	-	-	-	-	-	-
DEMHKHKO_00304	7.89e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DEMHKHKO_00305	8.2e-81	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
DEMHKHKO_00306	1.87e-53	-	-	-	-	-	-	-	-
DEMHKHKO_00307	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
DEMHKHKO_00308	2.05e-178	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DEMHKHKO_00309	3.7e-233	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
DEMHKHKO_00310	6.89e-190	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
DEMHKHKO_00311	5.95e-153	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
DEMHKHKO_00312	4.81e-188	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
DEMHKHKO_00313	5.76e-243	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
DEMHKHKO_00314	9.92e-143	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
DEMHKHKO_00315	4.57e-304	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
DEMHKHKO_00316	3.77e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DEMHKHKO_00317	2.87e-270	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DEMHKHKO_00318	3.39e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
DEMHKHKO_00319	1.17e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DEMHKHKO_00320	6.91e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DEMHKHKO_00321	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DEMHKHKO_00322	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DEMHKHKO_00323	4.22e-243	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
DEMHKHKO_00324	5.35e-133	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DEMHKHKO_00325	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
DEMHKHKO_00326	9.06e-279	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
DEMHKHKO_00327	1.83e-157	-	-	-	E	-	-	-	Methionine synthase
DEMHKHKO_00328	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
DEMHKHKO_00329	1.85e-121	-	-	-	-	-	-	-	-
DEMHKHKO_00330	1.25e-199	-	-	-	T	-	-	-	EAL domain
DEMHKHKO_00331	2.24e-206	-	-	-	GM	-	-	-	NmrA-like family
DEMHKHKO_00332	5.67e-280	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
DEMHKHKO_00333	3.1e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
DEMHKHKO_00334	0.0	pucR_2	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
DEMHKHKO_00335	7.13e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DEMHKHKO_00336	2.02e-219	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
DEMHKHKO_00337	1.61e-308	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
DEMHKHKO_00338	2.76e-271	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
DEMHKHKO_00339	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
DEMHKHKO_00340	1.04e-218	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
DEMHKHKO_00341	1.55e-161	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
DEMHKHKO_00342	5.46e-145	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DEMHKHKO_00343	1.12e-216	oroP	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
DEMHKHKO_00344	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
DEMHKHKO_00345	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
DEMHKHKO_00346	3.86e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
DEMHKHKO_00347	1.29e-148	-	-	-	GM	-	-	-	NAD(P)H-binding
DEMHKHKO_00348	6.68e-207	mleR	-	-	K	-	-	-	LysR family
DEMHKHKO_00349	2.09e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
DEMHKHKO_00350	3.59e-26	-	-	-	-	-	-	-	-
DEMHKHKO_00351	1.84e-204	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DEMHKHKO_00352	1.02e-277	araT2	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
DEMHKHKO_00353	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	Bacterial regulatory proteins, gntR family
DEMHKHKO_00354	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DEMHKHKO_00355	4.71e-74	-	-	-	S	-	-	-	SdpI/YhfL protein family
DEMHKHKO_00356	4.68e-161	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
DEMHKHKO_00357	9.75e-39	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
DEMHKHKO_00358	3.45e-83	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
DEMHKHKO_00359	2.03e-271	yttB	-	-	EGP	-	-	-	Major Facilitator
DEMHKHKO_00360	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
DEMHKHKO_00361	1.18e-114	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
DEMHKHKO_00362	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
DEMHKHKO_00363	2.97e-76	-	-	-	-	-	-	-	-
DEMHKHKO_00364	2.61e-96	hsp2	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
DEMHKHKO_00365	1.55e-79	-	-	-	-	-	-	-	-
DEMHKHKO_00366	1.7e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
DEMHKHKO_00367	8.05e-179	rrp8	-	-	K	-	-	-	LytTr DNA-binding domain
DEMHKHKO_00368	1.97e-150	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
DEMHKHKO_00369	2.48e-178	-	-	-	-	-	-	-	-
DEMHKHKO_00370	4.75e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DEMHKHKO_00371	3.53e-169	-	-	-	K	-	-	-	Transcriptional regulator
DEMHKHKO_00372	2.01e-209	-	-	-	S	-	-	-	Putative esterase
DEMHKHKO_00373	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
DEMHKHKO_00374	1.25e-283	-	-	-	M	-	-	-	Glycosyl transferases group 1
DEMHKHKO_00375	1.38e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
DEMHKHKO_00376	4.05e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
DEMHKHKO_00377	2.5e-203	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
DEMHKHKO_00378	2.51e-103	uspA3	-	-	T	-	-	-	universal stress protein
DEMHKHKO_00379	0.0	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
DEMHKHKO_00380	4.26e-250	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
DEMHKHKO_00381	4.15e-78	-	-	-	-	-	-	-	-
DEMHKHKO_00382	1.65e-97	-	-	-	-	-	-	-	-
DEMHKHKO_00383	6.94e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2798)
DEMHKHKO_00384	2.57e-70	-	-	-	-	-	-	-	-
DEMHKHKO_00385	3.89e-62	-	-	-	-	-	-	-	-
DEMHKHKO_00386	3.87e-262	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
DEMHKHKO_00387	9.89e-74	ytpP	-	-	CO	-	-	-	Thioredoxin
DEMHKHKO_00388	1.19e-186	-	-	-	S	ko:K06889	-	ko00000	Dienelactone hydrolase family
DEMHKHKO_00389	1.83e-37	-	-	-	-	-	-	-	-
DEMHKHKO_00390	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
DEMHKHKO_00391	2.8e-63	-	-	-	-	-	-	-	-
DEMHKHKO_00392	1.23e-75	-	-	-	-	-	-	-	-
DEMHKHKO_00393	1.86e-210	-	-	-	-	-	-	-	-
DEMHKHKO_00394	1.4e-95	-	-	-	K	-	-	-	Transcriptional regulator
DEMHKHKO_00395	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
DEMHKHKO_00396	8.94e-221	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
DEMHKHKO_00397	7.2e-61	-	-	-	S	-	-	-	Enterocin A Immunity
DEMHKHKO_00398	8.34e-86	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
DEMHKHKO_00399	1.01e-161	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
DEMHKHKO_00400	2.66e-172	-	-	-	-	-	-	-	-
DEMHKHKO_00401	9.38e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
DEMHKHKO_00402	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DEMHKHKO_00403	0.0	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
DEMHKHKO_00404	8.97e-253	yhhX	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
DEMHKHKO_00405	2.48e-227	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
DEMHKHKO_00406	5.91e-150	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
DEMHKHKO_00407	1.48e-201	ccpB	-	-	K	-	-	-	lacI family
DEMHKHKO_00408	2.2e-157	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
DEMHKHKO_00409	3.68e-203	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DEMHKHKO_00410	5.02e-228	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
DEMHKHKO_00411	3e-127	-	-	-	C	-	-	-	Nitroreductase family
DEMHKHKO_00412	6.04e-217	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
DEMHKHKO_00413	2.14e-183	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
DEMHKHKO_00414	2.71e-234	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
DEMHKHKO_00415	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
DEMHKHKO_00416	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
DEMHKHKO_00417	6.05e-98	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
DEMHKHKO_00418	1.78e-279	-	-	-	M	-	-	-	domain protein
DEMHKHKO_00419	6.32e-67	-	-	-	M	-	-	-	domain protein
DEMHKHKO_00420	1.01e-143	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
DEMHKHKO_00421	1.45e-46	-	-	-	-	-	-	-	-
DEMHKHKO_00422	5.48e-236	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
DEMHKHKO_00423	1.97e-254	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DEMHKHKO_00424	4.54e-126	-	-	-	J	-	-	-	glyoxalase III activity
DEMHKHKO_00425	1.01e-189	-	-	-	GM	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
DEMHKHKO_00426	4.73e-118	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
DEMHKHKO_00427	6.7e-74	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
DEMHKHKO_00428	7.28e-213	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
DEMHKHKO_00429	3.72e-283	ysaA	-	-	V	-	-	-	RDD family
DEMHKHKO_00430	4.54e-208	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
DEMHKHKO_00431	2.3e-275	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DEMHKHKO_00432	5.97e-107	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
DEMHKHKO_00433	7.8e-299	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DEMHKHKO_00434	2.46e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
DEMHKHKO_00435	2.23e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DEMHKHKO_00436	5.62e-165	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DEMHKHKO_00437	1.27e-172	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
DEMHKHKO_00438	6.12e-78	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DEMHKHKO_00439	1.07e-68	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
DEMHKHKO_00440	1.9e-258	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DEMHKHKO_00441	2.47e-125	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
DEMHKHKO_00442	1.18e-175	yceF	-	-	P	ko:K05794	-	ko00000	membrane
DEMHKHKO_00443	9.51e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
DEMHKHKO_00444	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
DEMHKHKO_00445	1.32e-178	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DEMHKHKO_00446	6.03e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
DEMHKHKO_00447	9.31e-225	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
DEMHKHKO_00448	1.53e-213	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
DEMHKHKO_00449	6.08e-312	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
DEMHKHKO_00450	6.83e-292	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
DEMHKHKO_00451	3.45e-209	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
DEMHKHKO_00452	1.31e-242	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DEMHKHKO_00453	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
DEMHKHKO_00454	2.64e-61	-	-	-	-	-	-	-	-
DEMHKHKO_00455	2.35e-106	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DEMHKHKO_00456	9.24e-140	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
DEMHKHKO_00457	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
DEMHKHKO_00458	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DEMHKHKO_00459	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DEMHKHKO_00460	2.18e-182	ybbR	-	-	S	-	-	-	YbbR-like protein
DEMHKHKO_00461	2.39e-191	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DEMHKHKO_00462	8.06e-156	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
DEMHKHKO_00463	3.07e-119	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
DEMHKHKO_00464	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
DEMHKHKO_00465	6.24e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
DEMHKHKO_00466	3.09e-213	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
DEMHKHKO_00467	2.53e-198	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
DEMHKHKO_00468	2.41e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
DEMHKHKO_00469	2.52e-114	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
DEMHKHKO_00470	1.29e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
DEMHKHKO_00471	1.23e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
DEMHKHKO_00472	1.4e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DEMHKHKO_00473	1.98e-199	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
DEMHKHKO_00474	7.98e-137	-	-	-	-	-	-	-	-
DEMHKHKO_00475	9.36e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DEMHKHKO_00476	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DEMHKHKO_00477	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
DEMHKHKO_00478	2.4e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
DEMHKHKO_00479	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
DEMHKHKO_00480	3.83e-179	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
DEMHKHKO_00481	3.55e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
DEMHKHKO_00482	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
DEMHKHKO_00483	2.83e-168	-	-	-	-	-	-	-	-
DEMHKHKO_00484	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DEMHKHKO_00485	7.15e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DEMHKHKO_00486	1.31e-285	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
DEMHKHKO_00487	2.02e-245	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DEMHKHKO_00488	5.75e-242	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
DEMHKHKO_00489	1.14e-311	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
DEMHKHKO_00491	5.11e-133	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DEMHKHKO_00492	8.58e-223	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DEMHKHKO_00493	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
DEMHKHKO_00494	1.21e-215	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
DEMHKHKO_00495	5.32e-242	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
DEMHKHKO_00496	1.71e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
DEMHKHKO_00497	3.51e-113	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
DEMHKHKO_00498	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
DEMHKHKO_00499	7.5e-302	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
DEMHKHKO_00500	2.21e-113	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
DEMHKHKO_00501	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
DEMHKHKO_00502	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DEMHKHKO_00503	3.85e-151	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
DEMHKHKO_00504	5.33e-268	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
DEMHKHKO_00505	1.89e-134	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DEMHKHKO_00506	0.0	nox2	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
DEMHKHKO_00507	5.9e-170	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
DEMHKHKO_00508	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
DEMHKHKO_00509	7.54e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
DEMHKHKO_00510	4.31e-141	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
DEMHKHKO_00511	8.65e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
DEMHKHKO_00512	0.0	nox	-	-	C	-	-	-	NADH oxidase
DEMHKHKO_00513	6.37e-160	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
DEMHKHKO_00514	1.13e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
DEMHKHKO_00515	4e-235	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
DEMHKHKO_00516	6.26e-213	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DEMHKHKO_00517	2.55e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DEMHKHKO_00518	2.87e-71	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
DEMHKHKO_00519	2.78e-65	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
DEMHKHKO_00520	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
DEMHKHKO_00521	4.47e-177	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DEMHKHKO_00522	9.78e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DEMHKHKO_00523	5.04e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
DEMHKHKO_00524	9.05e-206	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
DEMHKHKO_00525	2.31e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
DEMHKHKO_00526	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
DEMHKHKO_00527	1.49e-170	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
DEMHKHKO_00528	1.05e-275	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
DEMHKHKO_00529	3.41e-257	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DEMHKHKO_00530	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DEMHKHKO_00531	1.27e-129	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DEMHKHKO_00532	2.94e-164	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
DEMHKHKO_00533	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
DEMHKHKO_00534	3.7e-149	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
DEMHKHKO_00535	6.57e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
DEMHKHKO_00536	7.29e-247	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
DEMHKHKO_00537	0.0	ydaO	-	-	E	-	-	-	amino acid
DEMHKHKO_00538	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
DEMHKHKO_00539	9.82e-55	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DEMHKHKO_00540	2.38e-140	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DEMHKHKO_00541	3.67e-154	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DEMHKHKO_00542	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
DEMHKHKO_00543	3.62e-249	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DEMHKHKO_00544	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
DEMHKHKO_00545	4.66e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
DEMHKHKO_00546	6.84e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
DEMHKHKO_00547	3.46e-242	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
DEMHKHKO_00548	3.8e-176	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DEMHKHKO_00549	2.18e-176	phnE2	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter permease
DEMHKHKO_00550	3.33e-184	phnE1	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DEMHKHKO_00551	2.8e-187	phnX	3.11.1.1	-	E	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the HAD-like hydrolase superfamily. PhnX family
DEMHKHKO_00552	5.35e-270	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
DEMHKHKO_00553	4.95e-246	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
DEMHKHKO_00554	1.29e-190	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
DEMHKHKO_00555	2.64e-213	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DEMHKHKO_00556	8.46e-77	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
DEMHKHKO_00557	2.33e-239	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
DEMHKHKO_00558	1.39e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
DEMHKHKO_00559	1.82e-152	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DEMHKHKO_00560	1.01e-51	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
DEMHKHKO_00561	6.22e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DEMHKHKO_00562	8.34e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DEMHKHKO_00563	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DEMHKHKO_00564	7.57e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
DEMHKHKO_00565	6.7e-141	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
DEMHKHKO_00566	8.42e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
DEMHKHKO_00567	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DEMHKHKO_00568	2.47e-253	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DEMHKHKO_00569	2.37e-140	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
DEMHKHKO_00570	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DEMHKHKO_00571	4.82e-86	-	-	-	L	-	-	-	nuclease
DEMHKHKO_00572	1.01e-226	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
DEMHKHKO_00573	2.76e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
DEMHKHKO_00574	3.72e-105	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DEMHKHKO_00575	2.69e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
DEMHKHKO_00576	9.76e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DEMHKHKO_00577	2.81e-202	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
DEMHKHKO_00578	1.89e-128	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
DEMHKHKO_00579	1e-39	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
DEMHKHKO_00580	4.55e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
DEMHKHKO_00581	1.12e-130	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
DEMHKHKO_00582	1.44e-125	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
DEMHKHKO_00583	1.49e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DEMHKHKO_00584	1.35e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DEMHKHKO_00585	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
DEMHKHKO_00586	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DEMHKHKO_00587	4.91e-265	yacL	-	-	S	-	-	-	domain protein
DEMHKHKO_00588	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DEMHKHKO_00589	9.43e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
DEMHKHKO_00590	5.96e-69	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
DEMHKHKO_00591	1.62e-158	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DEMHKHKO_00592	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
DEMHKHKO_00593	3.22e-147	zmp2	-	-	O	-	-	-	Zinc-dependent metalloprotease
DEMHKHKO_00594	1.91e-165	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DEMHKHKO_00595	1.22e-226	-	-	-	EG	-	-	-	EamA-like transporter family
DEMHKHKO_00596	3.06e-214	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
DEMHKHKO_00597	5.37e-233	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
DEMHKHKO_00598	1.05e-172	accA1	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
DEMHKHKO_00599	1.49e-183	accD1	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DEMHKHKO_00600	1.7e-315	accC1	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
DEMHKHKO_00601	9.24e-85	accB1	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin-requiring enzyme
DEMHKHKO_00602	3.15e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DEMHKHKO_00603	4.5e-113	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
DEMHKHKO_00604	4.16e-93	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
DEMHKHKO_00605	0.0	levR	-	-	K	-	-	-	Sigma-54 interaction domain
DEMHKHKO_00606	9.05e-85	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
DEMHKHKO_00607	4.22e-216	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
DEMHKHKO_00608	4.51e-172	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
DEMHKHKO_00609	6.46e-218	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
DEMHKHKO_00610	1.53e-195	-	-	-	G	-	-	-	Peptidase_C39 like family
DEMHKHKO_00612	1.9e-198	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
DEMHKHKO_00613	1.71e-302	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
DEMHKHKO_00614	3.09e-106	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
DEMHKHKO_00615	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
DEMHKHKO_00616	2.57e-94	-	-	-	-	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	-
DEMHKHKO_00617	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
DEMHKHKO_00618	1.51e-196	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
DEMHKHKO_00619	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DEMHKHKO_00620	5.44e-175	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
DEMHKHKO_00621	5.41e-160	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
DEMHKHKO_00622	2.92e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DEMHKHKO_00623	2.18e-174	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DEMHKHKO_00624	1.06e-195	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
DEMHKHKO_00625	1.59e-247	ysdE	-	-	P	-	-	-	Citrate transporter
DEMHKHKO_00626	3.1e-212	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
DEMHKHKO_00627	1.38e-71	-	-	-	S	-	-	-	Cupin domain
DEMHKHKO_00628	9.02e-66	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
DEMHKHKO_00632	1.75e-193	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
DEMHKHKO_00633	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
DEMHKHKO_00635	8.59e-85	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
DEMHKHKO_00636	1.13e-182	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
DEMHKHKO_00637	3.66e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DEMHKHKO_00638	3.3e-202	degV1	-	-	S	-	-	-	DegV family
DEMHKHKO_00639	2.89e-80	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
DEMHKHKO_00640	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
DEMHKHKO_00642	2.76e-141	sip3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
DEMHKHKO_00643	0.0	-	-	-	-	-	-	-	-
DEMHKHKO_00645	2.13e-209	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
DEMHKHKO_00646	2.16e-142	-	-	-	S	-	-	-	Cell surface protein
DEMHKHKO_00647	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
DEMHKHKO_00648	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DEMHKHKO_00649	2.14e-155	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
DEMHKHKO_00650	3.75e-305	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
DEMHKHKO_00651	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
DEMHKHKO_00652	1.55e-158	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DEMHKHKO_00653	3.74e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
DEMHKHKO_00654	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DEMHKHKO_00655	8.19e-267	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
DEMHKHKO_00656	3.82e-51	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
DEMHKHKO_00657	7.24e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DEMHKHKO_00658	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DEMHKHKO_00659	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DEMHKHKO_00660	5.95e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
DEMHKHKO_00661	1.59e-95	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
DEMHKHKO_00662	2.69e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DEMHKHKO_00663	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
DEMHKHKO_00664	3.44e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
DEMHKHKO_00665	8.77e-317	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
DEMHKHKO_00666	4.96e-289	yttB	-	-	EGP	-	-	-	Major Facilitator
DEMHKHKO_00667	9e-184	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DEMHKHKO_00668	2.19e-290	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DEMHKHKO_00670	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
DEMHKHKO_00671	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DEMHKHKO_00672	6.65e-282	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DEMHKHKO_00673	3.49e-269	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
DEMHKHKO_00674	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
DEMHKHKO_00675	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
DEMHKHKO_00676	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
DEMHKHKO_00677	8.38e-184	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
DEMHKHKO_00678	1.1e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
DEMHKHKO_00679	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
DEMHKHKO_00680	3.21e-104	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
DEMHKHKO_00681	4.37e-43	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein domain
DEMHKHKO_00682	2.54e-50	-	-	-	-	-	-	-	-
DEMHKHKO_00684	2.22e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
DEMHKHKO_00685	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
DEMHKHKO_00686	3.55e-313	yycH	-	-	S	-	-	-	YycH protein
DEMHKHKO_00687	3.54e-195	yycI	-	-	S	-	-	-	YycH protein
DEMHKHKO_00688	1.71e-200	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
DEMHKHKO_00689	1.5e-253	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
DEMHKHKO_00690	6.08e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DEMHKHKO_00691	3.46e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DEMHKHKO_00692	0.0	-	-	-	C	-	-	-	Belongs to the aldehyde dehydrogenase family
DEMHKHKO_00693	6.96e-214	-	-	-	L	-	-	-	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
DEMHKHKO_00694	5.97e-157	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
DEMHKHKO_00695	4.75e-42	pnb	-	-	C	-	-	-	nitroreductase
DEMHKHKO_00696	5.63e-86	pnb	-	-	C	-	-	-	nitroreductase
DEMHKHKO_00697	4.95e-86	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
DEMHKHKO_00698	1.57e-150	-	-	-	S	-	-	-	Elongation factor G-binding protein, N-terminal
DEMHKHKO_00699	0.0	-	-	-	C	-	-	-	FMN_bind
DEMHKHKO_00700	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
DEMHKHKO_00701	1.46e-204	-	-	-	K	-	-	-	LysR family
DEMHKHKO_00702	2.49e-95	-	-	-	C	-	-	-	FMN binding
DEMHKHKO_00703	4.48e-98	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DEMHKHKO_00704	4.06e-211	-	-	-	S	-	-	-	KR domain
DEMHKHKO_00705	5.74e-204	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
DEMHKHKO_00706	5.07e-157	ydgI	-	-	C	-	-	-	Nitroreductase family
DEMHKHKO_00707	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
DEMHKHKO_00708	1.56e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
DEMHKHKO_00709	7.63e-249	pva1	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
DEMHKHKO_00710	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
DEMHKHKO_00711	6.86e-175	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
DEMHKHKO_00712	0.0	hpaH	1.14.14.8, 1.14.14.9	-	Q	ko:K00483,ko:K16901	ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220	ko00000,ko00001,ko01000	4-hydroxyphenylacetate
DEMHKHKO_00713	1.65e-106	-	-	-	S	-	-	-	ASCH
DEMHKHKO_00714	1.25e-164	-	-	-	F	-	-	-	glutamine amidotransferase
DEMHKHKO_00715	1.67e-220	-	-	-	K	-	-	-	WYL domain
DEMHKHKO_00716	1.63e-152	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DEMHKHKO_00717	0.0	fusA1	-	-	J	-	-	-	elongation factor G
DEMHKHKO_00718	7.44e-51	-	-	-	S	-	-	-	Protein of unknown function
DEMHKHKO_00719	2.7e-79	-	-	-	S	-	-	-	Protein of unknown function
DEMHKHKO_00720	8.64e-195	-	-	-	EG	-	-	-	EamA-like transporter family
DEMHKHKO_00721	7.65e-121	yfbM	-	-	K	-	-	-	FR47-like protein
DEMHKHKO_00722	1.4e-162	-	-	-	S	-	-	-	DJ-1/PfpI family
DEMHKHKO_00723	3.14e-230	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
DEMHKHKO_00724	1.02e-63	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
DEMHKHKO_00725	5.98e-302	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
DEMHKHKO_00726	4.77e-215	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
DEMHKHKO_00727	7.76e-181	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
DEMHKHKO_00728	2.38e-99	-	-	-	-	-	-	-	-
DEMHKHKO_00729	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
DEMHKHKO_00730	2.4e-180	-	-	-	-	-	-	-	-
DEMHKHKO_00731	4.07e-05	-	-	-	-	-	-	-	-
DEMHKHKO_00732	5.66e-184	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
DEMHKHKO_00733	1.67e-54	-	-	-	-	-	-	-	-
DEMHKHKO_00734	4.29e-166	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DEMHKHKO_00735	9.79e-192	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
DEMHKHKO_00736	1.84e-235	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
DEMHKHKO_00737	1.15e-155	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
DEMHKHKO_00738	7.9e-306	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
DEMHKHKO_00739	1.78e-160	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
DEMHKHKO_00740	3.58e-174	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
DEMHKHKO_00741	1.19e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
DEMHKHKO_00742	2.6e-193	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
DEMHKHKO_00743	7.11e-227	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
DEMHKHKO_00745	1.87e-175	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DEMHKHKO_00746	7.44e-192	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
DEMHKHKO_00747	1.61e-144	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
DEMHKHKO_00748	1.45e-261	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
DEMHKHKO_00749	2.39e-174	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
DEMHKHKO_00750	0.0	-	-	-	L	-	-	-	HIRAN domain
DEMHKHKO_00751	1.24e-109	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
DEMHKHKO_00752	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
DEMHKHKO_00753	5.18e-159	-	-	-	-	-	-	-	-
DEMHKHKO_00754	2.07e-191	-	-	-	I	-	-	-	Alpha/beta hydrolase family
DEMHKHKO_00755	0.0	pacL1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
DEMHKHKO_00756	1.34e-183	-	-	-	F	-	-	-	Phosphorylase superfamily
DEMHKHKO_00757	2.92e-38	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
DEMHKHKO_00758	1.72e-142	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
DEMHKHKO_00759	1.27e-98	-	-	-	K	-	-	-	Transcriptional regulator
DEMHKHKO_00760	3.99e-96	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
DEMHKHKO_00761	5.51e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
DEMHKHKO_00762	5.38e-290	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
DEMHKHKO_00763	3.98e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
DEMHKHKO_00764	2.79e-274	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
DEMHKHKO_00766	2.16e-204	morA	-	-	S	-	-	-	reductase
DEMHKHKO_00767	8.21e-213	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo keto reductase
DEMHKHKO_00768	1.92e-106	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase like
DEMHKHKO_00769	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
DEMHKHKO_00770	7.45e-103	-	-	-	-	-	-	-	-
DEMHKHKO_00771	0.0	-	-	-	-	-	-	-	-
DEMHKHKO_00772	6.49e-268	-	-	-	C	-	-	-	Oxidoreductase
DEMHKHKO_00773	3.28e-193	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
DEMHKHKO_00774	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DEMHKHKO_00775	2.57e-128	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
DEMHKHKO_00777	4.37e-167	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
DEMHKHKO_00778	4.14e-72	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
DEMHKHKO_00779	2.09e-171	-	-	-	-	-	-	-	-
DEMHKHKO_00780	1.57e-191	-	-	-	-	-	-	-	-
DEMHKHKO_00781	3.37e-115	-	-	-	-	-	-	-	-
DEMHKHKO_00782	1.01e-184	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
DEMHKHKO_00783	6.03e-218	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
DEMHKHKO_00784	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
DEMHKHKO_00785	8.03e-151	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
DEMHKHKO_00786	0.0	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
DEMHKHKO_00787	9.67e-98	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
DEMHKHKO_00789	5.29e-121	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DEMHKHKO_00790	2.35e-243	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
DEMHKHKO_00791	3.05e-236	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
DEMHKHKO_00792	7.88e-131	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
DEMHKHKO_00793	6.76e-75	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
DEMHKHKO_00794	2.32e-171	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
DEMHKHKO_00795	2.65e-245	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
DEMHKHKO_00796	1.83e-231	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
DEMHKHKO_00797	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
DEMHKHKO_00798	7.17e-62	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
DEMHKHKO_00799	2.15e-07	-	-	-	K	-	-	-	transcriptional regulator
DEMHKHKO_00800	5.58e-274	-	-	-	S	-	-	-	membrane
DEMHKHKO_00801	1.51e-105	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DEMHKHKO_00802	0.0	-	-	-	S	-	-	-	Zinc finger, swim domain protein
DEMHKHKO_00803	8.09e-146	-	-	-	GM	-	-	-	epimerase
DEMHKHKO_00804	6.34e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
DEMHKHKO_00805	2.65e-93	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
DEMHKHKO_00806	1.4e-137	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
DEMHKHKO_00807	1.68e-176	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
DEMHKHKO_00808	0.0	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
DEMHKHKO_00809	1.3e-264	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
DEMHKHKO_00810	4.38e-102	-	-	-	K	-	-	-	Transcriptional regulator
DEMHKHKO_00811	4.6e-307	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
DEMHKHKO_00812	1.27e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DEMHKHKO_00813	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
DEMHKHKO_00814	1.68e-229	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
DEMHKHKO_00815	4.8e-278	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
DEMHKHKO_00816	1.93e-266	-	-	-	-	-	-	-	-
DEMHKHKO_00817	6.11e-118	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
DEMHKHKO_00818	2.65e-81	-	-	-	P	-	-	-	Rhodanese Homology Domain
DEMHKHKO_00819	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
DEMHKHKO_00820	2.74e-112	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
DEMHKHKO_00821	2.08e-213	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
DEMHKHKO_00822	2.52e-165	drrB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
DEMHKHKO_00823	1.75e-295	-	-	-	M	-	-	-	O-Antigen ligase
DEMHKHKO_00824	6.85e-164	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
DEMHKHKO_00825	1.09e-249	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DEMHKHKO_00826	1.29e-298	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
DEMHKHKO_00827	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
DEMHKHKO_00829	7.03e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
DEMHKHKO_00830	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
DEMHKHKO_00831	8.69e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
DEMHKHKO_00832	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
DEMHKHKO_00833	2.51e-98	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
DEMHKHKO_00834	4.59e-217	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
DEMHKHKO_00835	3.13e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
DEMHKHKO_00836	3.99e-92	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DEMHKHKO_00837	7.1e-176	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DEMHKHKO_00838	1.3e-132	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DEMHKHKO_00839	2.69e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
DEMHKHKO_00840	2.24e-126	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DEMHKHKO_00841	3.38e-252	-	-	-	S	-	-	-	Helix-turn-helix domain
DEMHKHKO_00842	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
DEMHKHKO_00843	1.25e-39	-	-	-	M	-	-	-	Lysin motif
DEMHKHKO_00844	1.27e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
DEMHKHKO_00845	1.98e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
DEMHKHKO_00846	5.89e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
DEMHKHKO_00847	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
DEMHKHKO_00848	2.08e-284	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
DEMHKHKO_00849	1.29e-192	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
DEMHKHKO_00850	1.39e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
DEMHKHKO_00851	6.04e-290	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
DEMHKHKO_00852	6.46e-109	-	-	-	-	-	-	-	-
DEMHKHKO_00853	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
DEMHKHKO_00854	6.7e-241	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DEMHKHKO_00855	1.8e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DEMHKHKO_00856	2.03e-189	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
DEMHKHKO_00857	1.19e-208	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
DEMHKHKO_00858	3.29e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
DEMHKHKO_00859	9.33e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
DEMHKHKO_00860	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
DEMHKHKO_00861	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
DEMHKHKO_00862	4.28e-253	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
DEMHKHKO_00863	3.53e-160	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
DEMHKHKO_00864	1.27e-222	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
DEMHKHKO_00865	1.73e-219	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
DEMHKHKO_00866	5.99e-291	XK27_05470	-	-	E	-	-	-	Methionine synthase
DEMHKHKO_00868	2.25e-207	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DEMHKHKO_00869	8.64e-177	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DEMHKHKO_00870	2.33e-202	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
DEMHKHKO_00871	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DEMHKHKO_00872	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DEMHKHKO_00873	1.5e-227	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
DEMHKHKO_00874	6.84e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DEMHKHKO_00875	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DEMHKHKO_00876	3.64e-217	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
DEMHKHKO_00877	2.4e-137	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
DEMHKHKO_00878	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DEMHKHKO_00879	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DEMHKHKO_00880	2.21e-227	-	-	-	K	-	-	-	Transcriptional regulator
DEMHKHKO_00881	3.21e-215	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
DEMHKHKO_00882	3.8e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
DEMHKHKO_00883	9.17e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DEMHKHKO_00884	1.07e-43	-	-	-	S	-	-	-	YozE SAM-like fold
DEMHKHKO_00885	3.59e-204	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
DEMHKHKO_00886	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DEMHKHKO_00887	4.49e-315	-	-	-	M	-	-	-	Glycosyl transferase family group 2
DEMHKHKO_00888	3.22e-87	-	-	-	-	-	-	-	-
DEMHKHKO_00889	0.0	gshR1	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
DEMHKHKO_00890	1.48e-98	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
DEMHKHKO_00891	4.87e-123	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
DEMHKHKO_00892	0.0	tarL	2.7.8.14, 2.7.8.47	-	H	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
DEMHKHKO_00893	1.43e-273	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	H	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
DEMHKHKO_00894	6.51e-247	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
DEMHKHKO_00895	2.13e-151	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
DEMHKHKO_00896	4.76e-290	-	-	-	-	-	-	-	-
DEMHKHKO_00897	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
DEMHKHKO_00898	7.79e-78	-	-	-	-	-	-	-	-
DEMHKHKO_00899	2.79e-181	-	-	-	-	-	-	-	-
DEMHKHKO_00900	1.06e-312	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
DEMHKHKO_00901	1.05e-176	XK27_00890	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
DEMHKHKO_00902	9.3e-167	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
DEMHKHKO_00903	1.33e-67	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
DEMHKHKO_00905	6e-268	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
DEMHKHKO_00906	4.87e-191	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
DEMHKHKO_00907	2.37e-65	-	-	-	-	-	-	-	-
DEMHKHKO_00908	1.27e-35	-	-	-	-	-	-	-	-
DEMHKHKO_00909	1.96e-168	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
DEMHKHKO_00910	2.47e-101	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
DEMHKHKO_00911	4.53e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
DEMHKHKO_00912	1.97e-87	-	-	-	K	-	-	-	Transcriptional regulator
DEMHKHKO_00913	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
DEMHKHKO_00914	1.6e-171	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
DEMHKHKO_00915	2.16e-208	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DEMHKHKO_00916	1.37e-119	-	-	-	F	-	-	-	NUDIX domain
DEMHKHKO_00917	1.19e-176	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
DEMHKHKO_00918	2.08e-92	-	-	-	S	-	-	-	LuxR family transcriptional regulator
DEMHKHKO_00919	1.92e-168	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
DEMHKHKO_00922	1.9e-93	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
DEMHKHKO_00923	3.34e-144	-	-	-	G	-	-	-	Phosphoglycerate mutase family
DEMHKHKO_00924	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
DEMHKHKO_00925	4.89e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
DEMHKHKO_00926	1.9e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DEMHKHKO_00927	9.72e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
DEMHKHKO_00928	1.65e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DEMHKHKO_00929	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
DEMHKHKO_00930	5.89e-81	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
DEMHKHKO_00931	3.28e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
DEMHKHKO_00932	2.44e-267	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
DEMHKHKO_00933	2.13e-186	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
DEMHKHKO_00934	2.27e-247	-	-	-	-	-	-	-	-
DEMHKHKO_00935	1.9e-156	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
DEMHKHKO_00936	4.35e-159	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
DEMHKHKO_00937	1.38e-232	-	-	-	V	-	-	-	LD-carboxypeptidase
DEMHKHKO_00938	1.23e-311	-	-	-	M	ko:K07273	-	ko00000	hydrolase, family 25
DEMHKHKO_00939	1.01e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
DEMHKHKO_00940	4.82e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
DEMHKHKO_00941	1.81e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DEMHKHKO_00942	5.41e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DEMHKHKO_00943	2.03e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DEMHKHKO_00944	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DEMHKHKO_00945	9.14e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DEMHKHKO_00946	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DEMHKHKO_00947	5.95e-74	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
DEMHKHKO_00948	4.85e-314	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DEMHKHKO_00949	1.68e-132	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
DEMHKHKO_00950	1.44e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
DEMHKHKO_00951	1.52e-57	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
DEMHKHKO_00952	1.04e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
DEMHKHKO_00953	2.15e-280	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
DEMHKHKO_00954	3.2e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
DEMHKHKO_00955	2.24e-239	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DEMHKHKO_00956	2.1e-151	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DEMHKHKO_00957	8.69e-191	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
DEMHKHKO_00958	3.34e-215	hicD3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
DEMHKHKO_00959	3.26e-227	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
DEMHKHKO_00960	7.55e-242	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
DEMHKHKO_00961	6.54e-273	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
DEMHKHKO_00962	0.0	glpQ3	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
DEMHKHKO_00963	4.7e-207	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DEMHKHKO_00964	1.1e-258	bla2	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
DEMHKHKO_00965	2.37e-107	uspA	-	-	T	-	-	-	universal stress protein
DEMHKHKO_00966	1.34e-52	-	-	-	-	-	-	-	-
DEMHKHKO_00967	7.27e-303	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
DEMHKHKO_00968	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
DEMHKHKO_00969	9.17e-59	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
DEMHKHKO_00970	1.24e-139	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
DEMHKHKO_00971	1.63e-104	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
DEMHKHKO_00972	4.02e-145	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
DEMHKHKO_00973	2.15e-137	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DEMHKHKO_00974	7.5e-105	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
DEMHKHKO_00975	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DEMHKHKO_00976	2.59e-277	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
DEMHKHKO_00977	8.93e-291	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DEMHKHKO_00978	1.57e-299	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
DEMHKHKO_00979	3.56e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DEMHKHKO_00980	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
DEMHKHKO_00981	5.62e-316	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
DEMHKHKO_00982	1.15e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
DEMHKHKO_00983	1.74e-211	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
DEMHKHKO_00984	3.76e-184	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
DEMHKHKO_00985	9.47e-115	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
DEMHKHKO_00986	3.81e-150	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
DEMHKHKO_00987	1.23e-187	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
DEMHKHKO_00988	1.89e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
DEMHKHKO_00989	3.17e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DEMHKHKO_00990	2.61e-199	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
DEMHKHKO_00991	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
DEMHKHKO_00992	3.55e-296	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
DEMHKHKO_00993	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
DEMHKHKO_00994	5.74e-172	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
DEMHKHKO_00995	1.92e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DEMHKHKO_00996	3.83e-295	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
DEMHKHKO_00997	2.43e-264	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DEMHKHKO_00998	6.57e-291	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
DEMHKHKO_00999	6.18e-197	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
DEMHKHKO_01000	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DEMHKHKO_01001	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DEMHKHKO_01002	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
DEMHKHKO_01003	1.3e-91	-	-	-	-	-	-	-	-
DEMHKHKO_01004	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
DEMHKHKO_01005	4.02e-114	-	-	-	-	-	-	-	-
DEMHKHKO_01006	2.83e-138	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
DEMHKHKO_01007	2.62e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
DEMHKHKO_01008	5.87e-256	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DEMHKHKO_01009	9.91e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
DEMHKHKO_01010	1.32e-63	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
DEMHKHKO_01011	2.48e-276	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DEMHKHKO_01012	8.32e-227	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
DEMHKHKO_01013	2.79e-316	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
DEMHKHKO_01014	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DEMHKHKO_01015	5e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
DEMHKHKO_01016	5.39e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DEMHKHKO_01017	1.31e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
DEMHKHKO_01018	1.06e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DEMHKHKO_01019	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
DEMHKHKO_01020	3e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
DEMHKHKO_01021	1.45e-161	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
DEMHKHKO_01022	5.06e-194	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
DEMHKHKO_01023	8.49e-144	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DEMHKHKO_01024	4.03e-125	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
DEMHKHKO_01025	7.94e-114	ykuL	-	-	S	-	-	-	(CBS) domain
DEMHKHKO_01026	2.29e-112	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
DEMHKHKO_01027	6.72e-289	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
DEMHKHKO_01028	2.31e-202	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
DEMHKHKO_01029	1.88e-75	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DEMHKHKO_01030	1.6e-96	-	-	-	-	-	-	-	-
DEMHKHKO_01031	9.86e-82	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
DEMHKHKO_01032	7.36e-274	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
DEMHKHKO_01033	5.44e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
DEMHKHKO_01034	3.21e-210	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
DEMHKHKO_01035	2.44e-65	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
DEMHKHKO_01036	2.21e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
DEMHKHKO_01037	2.06e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEMHKHKO_01038	2.57e-224	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
DEMHKHKO_01039	6.2e-242	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
DEMHKHKO_01040	1.97e-72	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
DEMHKHKO_01041	1.5e-108	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
DEMHKHKO_01042	3.03e-27	-	-	-	-	ko:K02671	-	ko00000,ko02035,ko02044	-
DEMHKHKO_01043	6.46e-113	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
DEMHKHKO_01045	3.68e-235	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
DEMHKHKO_01046	4.7e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DEMHKHKO_01047	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
DEMHKHKO_01048	5.77e-151	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
DEMHKHKO_01049	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
DEMHKHKO_01050	1.96e-116	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
DEMHKHKO_01051	7.18e-189	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
DEMHKHKO_01052	2.71e-150	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
DEMHKHKO_01053	8.38e-152	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
DEMHKHKO_01054	5.16e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DEMHKHKO_01055	2e-98	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	general stress protein
DEMHKHKO_01056	4.92e-212	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
DEMHKHKO_01057	4.87e-234	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
DEMHKHKO_01058	1.89e-208	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
DEMHKHKO_01059	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DEMHKHKO_01060	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
DEMHKHKO_01061	7.76e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
DEMHKHKO_01062	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
DEMHKHKO_01063	0.0	-	-	-	S	ko:K06889	-	ko00000	Alpha beta
DEMHKHKO_01064	6.07e-33	-	-	-	-	-	-	-	-
DEMHKHKO_01065	4.37e-128	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
DEMHKHKO_01066	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
DEMHKHKO_01067	2.6e-212	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
DEMHKHKO_01068	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
DEMHKHKO_01069	1.53e-213	mleR	-	-	K	-	-	-	LysR family
DEMHKHKO_01070	4.54e-207	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
DEMHKHKO_01071	2.32e-121	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
DEMHKHKO_01072	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
DEMHKHKO_01073	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
DEMHKHKO_01074	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
DEMHKHKO_01075	1.51e-206	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
DEMHKHKO_01076	1.23e-58	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
DEMHKHKO_01077	3.07e-241	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
DEMHKHKO_01078	1.11e-263	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
DEMHKHKO_01079	8.69e-230	citR	-	-	K	-	-	-	sugar-binding domain protein
DEMHKHKO_01080	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
DEMHKHKO_01081	9.2e-215	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
DEMHKHKO_01082	1.18e-66	-	-	-	-	-	-	-	-
DEMHKHKO_01083	4.26e-222	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
DEMHKHKO_01084	1.76e-180	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
DEMHKHKO_01085	2.04e-170	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
DEMHKHKO_01086	3.16e-196	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
DEMHKHKO_01087	6.07e-252	-	-	-	K	-	-	-	Helix-turn-helix domain
DEMHKHKO_01088	4.28e-225	ttdA	4.2.1.32	-	C	ko:K03779	ko00630,map00630	ko00000,ko00001,ko01000	Fumarate hydratase (Fumerase)
DEMHKHKO_01089	1.41e-147	-	4.2.1.2, 4.2.1.32	-	C	ko:K01676,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
DEMHKHKO_01090	1.51e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
DEMHKHKO_01091	1.49e-281	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
DEMHKHKO_01092	1.33e-255	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DEMHKHKO_01093	3.3e-235	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	DAHP synthetase I family
DEMHKHKO_01094	1.65e-211	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DEMHKHKO_01095	0.0	tkt2	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DEMHKHKO_01096	1.07e-197	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
DEMHKHKO_01097	9.14e-38	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
DEMHKHKO_01098	1.68e-221	-	-	-	S	-	-	-	Membrane
DEMHKHKO_01099	8.51e-210	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
DEMHKHKO_01100	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
DEMHKHKO_01101	4.58e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DEMHKHKO_01102	3.06e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
DEMHKHKO_01103	2.29e-182	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DEMHKHKO_01104	2.01e-211	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DEMHKHKO_01105	1.98e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DEMHKHKO_01106	3.08e-264	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DEMHKHKO_01107	3.19e-194	-	-	-	S	-	-	-	FMN_bind
DEMHKHKO_01108	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
DEMHKHKO_01109	4.42e-111	-	-	-	S	-	-	-	NusG domain II
DEMHKHKO_01110	1.41e-122	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
DEMHKHKO_01111	1.02e-233	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
DEMHKHKO_01112	7.76e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
DEMHKHKO_01113	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DEMHKHKO_01114	7.71e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DEMHKHKO_01115	9.65e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DEMHKHKO_01116	9.87e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DEMHKHKO_01117	1.84e-160	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
DEMHKHKO_01118	5.95e-300	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
DEMHKHKO_01119	1.32e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
DEMHKHKO_01120	8.44e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
DEMHKHKO_01121	5.32e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DEMHKHKO_01122	1.75e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DEMHKHKO_01123	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DEMHKHKO_01124	4.99e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DEMHKHKO_01125	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DEMHKHKO_01126	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DEMHKHKO_01127	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DEMHKHKO_01128	1.96e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DEMHKHKO_01129	1.11e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
DEMHKHKO_01130	8.29e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DEMHKHKO_01131	5.46e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DEMHKHKO_01132	3.59e-69	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DEMHKHKO_01133	1.85e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DEMHKHKO_01134	6.61e-193	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DEMHKHKO_01135	2.27e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
DEMHKHKO_01136	9.83e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
DEMHKHKO_01137	1.24e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DEMHKHKO_01138	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
DEMHKHKO_01139	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DEMHKHKO_01140	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
DEMHKHKO_01141	4.19e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DEMHKHKO_01142	1.48e-149	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
DEMHKHKO_01143	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DEMHKHKO_01144	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DEMHKHKO_01145	1.16e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DEMHKHKO_01146	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
DEMHKHKO_01147	9.78e-102	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
DEMHKHKO_01155	1.62e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DEMHKHKO_01156	1.11e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
DEMHKHKO_01157	7.48e-153	dacB	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
DEMHKHKO_01158	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
DEMHKHKO_01159	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
DEMHKHKO_01160	5.68e-117	-	-	-	K	-	-	-	Transcriptional regulator
DEMHKHKO_01161	3.03e-129	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
DEMHKHKO_01162	3.88e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
DEMHKHKO_01163	4.15e-153	-	-	-	I	-	-	-	phosphatase
DEMHKHKO_01164	2.34e-242	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
DEMHKHKO_01165	7.76e-100	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
DEMHKHKO_01166	4.6e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
DEMHKHKO_01167	1.78e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
DEMHKHKO_01168	2.94e-155	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
DEMHKHKO_01169	1.36e-77	-	-	-	-	-	-	-	-
DEMHKHKO_01170	7.79e-112	-	-	-	K	-	-	-	MerR HTH family regulatory protein
DEMHKHKO_01171	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
DEMHKHKO_01172	2.72e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
DEMHKHKO_01173	1.46e-170	-	-	-	-	-	-	-	-
DEMHKHKO_01175	1.96e-293	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Cell cycle protein
DEMHKHKO_01176	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DEMHKHKO_01177	3.82e-184	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
DEMHKHKO_01178	4.46e-281	ywtF_2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
DEMHKHKO_01179	2.19e-131	-	-	-	L	-	-	-	Helix-turn-helix domain
DEMHKHKO_01180	1.14e-226	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family 2
DEMHKHKO_01181	3.81e-87	-	-	-	-	-	-	-	-
DEMHKHKO_01182	1.38e-98	-	-	-	-	-	-	-	-
DEMHKHKO_01183	1.56e-276	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
DEMHKHKO_01184	7.8e-123	-	-	-	-	-	-	-	-
DEMHKHKO_01185	7.22e-149	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DEMHKHKO_01186	7.68e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
DEMHKHKO_01187	3.96e-44	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
DEMHKHKO_01188	8.8e-155	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
DEMHKHKO_01189	2.11e-171	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
DEMHKHKO_01190	5.67e-64	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
DEMHKHKO_01191	1.92e-239	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DEMHKHKO_01192	2.92e-172	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
DEMHKHKO_01193	6.33e-185	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
DEMHKHKO_01194	1.88e-194	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DEMHKHKO_01195	3.01e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
DEMHKHKO_01196	9.83e-113	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
DEMHKHKO_01197	3.17e-190	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DEMHKHKO_01198	1.13e-175	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
DEMHKHKO_01199	4.64e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
DEMHKHKO_01200	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
DEMHKHKO_01201	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DEMHKHKO_01202	9.74e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
DEMHKHKO_01203	4.46e-275	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
DEMHKHKO_01204	2.95e-65	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
DEMHKHKO_01205	3.28e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
DEMHKHKO_01206	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DEMHKHKO_01207	3.04e-71	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DEMHKHKO_01208	0.0	-	-	-	G	-	-	-	Major Facilitator
DEMHKHKO_01209	3.67e-275	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DEMHKHKO_01210	1.63e-121	-	-	-	-	-	-	-	-
DEMHKHKO_01211	1.19e-285	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
DEMHKHKO_01212	1.21e-245	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
DEMHKHKO_01213	2.41e-113	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DEMHKHKO_01214	8.94e-221	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DEMHKHKO_01215	2.53e-240	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
DEMHKHKO_01216	1.19e-169	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
DEMHKHKO_01217	4.42e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
DEMHKHKO_01218	4.52e-111	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DEMHKHKO_01219	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
DEMHKHKO_01220	2.54e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
DEMHKHKO_01221	8.49e-266	pbpX2	-	-	V	-	-	-	Beta-lactamase
DEMHKHKO_01222	8.59e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
DEMHKHKO_01223	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DEMHKHKO_01224	3.27e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
DEMHKHKO_01225	5.75e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DEMHKHKO_01226	1.68e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DEMHKHKO_01227	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DEMHKHKO_01228	1.01e-158	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DEMHKHKO_01231	1.73e-67	-	-	-	-	-	-	-	-
DEMHKHKO_01232	4.78e-65	-	-	-	-	-	-	-	-
DEMHKHKO_01233	5.28e-146	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
DEMHKHKO_01234	2.04e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
DEMHKHKO_01235	3.13e-172	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
DEMHKHKO_01236	2.56e-76	-	-	-	-	-	-	-	-
DEMHKHKO_01237	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DEMHKHKO_01238	8.2e-102	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DEMHKHKO_01239	2.43e-150	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
DEMHKHKO_01240	2.29e-207	-	-	-	G	-	-	-	Fructosamine kinase
DEMHKHKO_01241	4.01e-200	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
DEMHKHKO_01242	2.47e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
DEMHKHKO_01243	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
DEMHKHKO_01244	2.61e-132	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DEMHKHKO_01245	4.35e-204	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DEMHKHKO_01246	1.84e-284	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
DEMHKHKO_01247	1.42e-217	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DEMHKHKO_01248	1.78e-140	-	-	-	C	-	-	-	Enoyl-(Acyl carrier protein) reductase
DEMHKHKO_01249	2.32e-194	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
DEMHKHKO_01250	1.09e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
DEMHKHKO_01251	9.21e-94	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
DEMHKHKO_01252	4.81e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
DEMHKHKO_01253	3.14e-109	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DEMHKHKO_01254	1.15e-94	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
DEMHKHKO_01255	7.92e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DEMHKHKO_01256	2.84e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
DEMHKHKO_01257	8.64e-224	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
DEMHKHKO_01258	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
DEMHKHKO_01259	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DEMHKHKO_01260	1.74e-251	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DEMHKHKO_01261	1.18e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
DEMHKHKO_01262	4.94e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DEMHKHKO_01263	5.23e-256	-	-	-	-	-	-	-	-
DEMHKHKO_01264	1.43e-251	-	-	-	-	-	-	-	-
DEMHKHKO_01265	6.05e-170	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
DEMHKHKO_01266	1.03e-206	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DEMHKHKO_01267	0.000138	yjdF	-	-	S	-	-	-	Protein of unknown function (DUF2992)
DEMHKHKO_01268	1.49e-147	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
DEMHKHKO_01269	2.25e-93	-	-	-	K	-	-	-	MarR family
DEMHKHKO_01270	6.64e-109	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
DEMHKHKO_01272	4.17e-204	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
DEMHKHKO_01273	1.27e-174	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
DEMHKHKO_01274	5.11e-266	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
DEMHKHKO_01275	1.51e-132	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
DEMHKHKO_01276	0.0	nox4	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
DEMHKHKO_01278	3.78e-221	cryZ	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
DEMHKHKO_01279	5.72e-207	-	-	-	K	-	-	-	Transcriptional regulator
DEMHKHKO_01280	1.74e-101	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
DEMHKHKO_01281	1.39e-143	-	-	-	GM	-	-	-	NmrA-like family
DEMHKHKO_01282	8.81e-205	-	-	-	S	-	-	-	Alpha beta hydrolase
DEMHKHKO_01283	2.49e-167	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
DEMHKHKO_01284	2.31e-132	thgA3	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
DEMHKHKO_01285	7.21e-145	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
DEMHKHKO_01286	1.56e-71	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
DEMHKHKO_01287	3.17e-170	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
DEMHKHKO_01288	1.63e-176	yesN	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
DEMHKHKO_01289	3.08e-113	-	-	-	K	-	-	-	Winged helix DNA-binding domain
DEMHKHKO_01290	3.81e-150	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DEMHKHKO_01291	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
DEMHKHKO_01292	4.45e-38	-	-	-	-	-	-	-	-
DEMHKHKO_01293	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
DEMHKHKO_01294	1.88e-96	-	-	-	M	-	-	-	PFAM NLP P60 protein
DEMHKHKO_01295	6.18e-71	-	-	-	-	-	-	-	-
DEMHKHKO_01296	5.77e-81	-	-	-	-	-	-	-	-
DEMHKHKO_01298	9.39e-84	-	-	-	-	-	-	-	-
DEMHKHKO_01300	1.12e-134	-	-	-	K	-	-	-	transcriptional regulator
DEMHKHKO_01301	4.84e-230	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
DEMHKHKO_01302	4.16e-175	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
DEMHKHKO_01303	1.5e-165	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
DEMHKHKO_01304	8.06e-232	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
DEMHKHKO_01305	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
DEMHKHKO_01306	9.44e-183	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
DEMHKHKO_01307	5.73e-73	trxA3	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
DEMHKHKO_01308	4.82e-55	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
DEMHKHKO_01309	1.01e-26	-	-	-	-	-	-	-	-
DEMHKHKO_01310	4.27e-126	dpsB	-	-	P	-	-	-	Belongs to the Dps family
DEMHKHKO_01311	2.98e-44	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
DEMHKHKO_01312	1.82e-152	rcfA	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
DEMHKHKO_01313	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
DEMHKHKO_01314	1.06e-106	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DEMHKHKO_01315	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
DEMHKHKO_01316	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
DEMHKHKO_01317	1.83e-235	-	-	-	S	-	-	-	Cell surface protein
DEMHKHKO_01318	8.67e-160	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
DEMHKHKO_01319	4.23e-129	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
DEMHKHKO_01320	7.83e-60	-	-	-	-	-	-	-	-
DEMHKHKO_01321	8.19e-134	yezE	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
DEMHKHKO_01322	1.03e-65	-	-	-	-	-	-	-	-
DEMHKHKO_01323	9.34e-317	-	-	-	S	-	-	-	Putative metallopeptidase domain
DEMHKHKO_01324	3.7e-279	-	-	-	S	-	-	-	associated with various cellular activities
DEMHKHKO_01325	1.95e-140	aqpZ	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
DEMHKHKO_01326	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
DEMHKHKO_01327	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
DEMHKHKO_01328	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
DEMHKHKO_01329	2.9e-293	-	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
DEMHKHKO_01330	0.0	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
DEMHKHKO_01331	5.91e-297	-	-	-	P	ko:K06610	-	ko00000,ko02000	Major Facilitator Superfamily
DEMHKHKO_01332	1.29e-235	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
DEMHKHKO_01333	3.38e-50	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
DEMHKHKO_01334	1.11e-33	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
DEMHKHKO_01335	6.61e-29	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
DEMHKHKO_01336	5.55e-100	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
DEMHKHKO_01337	1.55e-230	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
DEMHKHKO_01338	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
DEMHKHKO_01339	2.97e-244	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
DEMHKHKO_01340	1.92e-285	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DEMHKHKO_01341	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
DEMHKHKO_01342	5.49e-237	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
DEMHKHKO_01343	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
DEMHKHKO_01344	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
DEMHKHKO_01345	3.51e-252	galM3	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
DEMHKHKO_01346	3.69e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
DEMHKHKO_01347	1.42e-245	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
DEMHKHKO_01348	2.86e-85	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
DEMHKHKO_01349	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
DEMHKHKO_01350	1.23e-228	apbE3	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DEMHKHKO_01351	5.56e-167	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
DEMHKHKO_01352	1.33e-274	-	-	-	G	-	-	-	Transporter
DEMHKHKO_01353	1.66e-215	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DEMHKHKO_01354	5.79e-209	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
DEMHKHKO_01355	5.78e-269	-	-	-	G	-	-	-	Major Facilitator Superfamily
DEMHKHKO_01356	2.97e-83	-	-	-	-	-	-	-	-
DEMHKHKO_01357	1.78e-198	estA	-	-	S	-	-	-	Putative esterase
DEMHKHKO_01358	5.44e-174	-	-	-	K	-	-	-	UTRA domain
DEMHKHKO_01359	0.0	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DEMHKHKO_01360	1.55e-208	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DEMHKHKO_01361	6.87e-202	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
DEMHKHKO_01362	2.26e-269	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
DEMHKHKO_01363	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DEMHKHKO_01364	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
DEMHKHKO_01365	3.72e-200	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
DEMHKHKO_01366	0.0	pbg9	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DEMHKHKO_01367	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DEMHKHKO_01368	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
DEMHKHKO_01369	1.3e-203	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
DEMHKHKO_01370	0.0	treP	2.4.1.64	GH65	G	ko:K05342	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
DEMHKHKO_01371	1.08e-221	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
DEMHKHKO_01372	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
DEMHKHKO_01373	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
DEMHKHKO_01374	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
DEMHKHKO_01375	1.56e-46	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
DEMHKHKO_01376	3.91e-289	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
DEMHKHKO_01377	2.29e-292	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
DEMHKHKO_01378	2.16e-241	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DEMHKHKO_01379	2.04e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
DEMHKHKO_01380	1.41e-285	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
DEMHKHKO_01381	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DEMHKHKO_01382	1.24e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
DEMHKHKO_01383	5.6e-41	-	-	-	-	-	-	-	-
DEMHKHKO_01384	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
DEMHKHKO_01385	3.29e-95	-	-	-	L	-	-	-	Integrase
DEMHKHKO_01386	3.4e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
DEMHKHKO_01387	5.67e-231	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
DEMHKHKO_01388	4.86e-258	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
DEMHKHKO_01389	3.59e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEMHKHKO_01390	3.44e-210	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEMHKHKO_01391	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
DEMHKHKO_01392	3.85e-76	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
DEMHKHKO_01393	1.01e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
DEMHKHKO_01394	1.36e-208	lysR5	-	-	K	-	-	-	LysR substrate binding domain
DEMHKHKO_01395	1.01e-250	-	-	-	M	-	-	-	MucBP domain
DEMHKHKO_01396	0.0	-	-	-	-	-	-	-	-
DEMHKHKO_01397	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DEMHKHKO_01398	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
DEMHKHKO_01399	1.22e-218	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
DEMHKHKO_01400	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
DEMHKHKO_01401	7.89e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
DEMHKHKO_01402	6.04e-94	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
DEMHKHKO_01403	1.13e-257	yueF	-	-	S	-	-	-	AI-2E family transporter
DEMHKHKO_01404	7.3e-216	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
DEMHKHKO_01405	7.17e-39	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
DEMHKHKO_01406	3.97e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
DEMHKHKO_01407	1.94e-170	lytE	-	-	M	-	-	-	NlpC/P60 family
DEMHKHKO_01408	6.62e-138	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
DEMHKHKO_01409	1.01e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
DEMHKHKO_01410	1.34e-168	-	-	-	-	-	-	-	-
DEMHKHKO_01411	1.68e-131	-	-	-	K	-	-	-	DNA-templated transcription, initiation
DEMHKHKO_01412	3.31e-35	-	-	-	-	-	-	-	-
DEMHKHKO_01413	1.95e-41	-	-	-	-	-	-	-	-
DEMHKHKO_01414	1.04e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
DEMHKHKO_01415	9.02e-70	-	-	-	-	-	-	-	-
DEMHKHKO_01417	3.98e-169	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
DEMHKHKO_01418	1.95e-197	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
DEMHKHKO_01419	3.34e-267	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
DEMHKHKO_01420	3.3e-281	pbpX	-	-	V	-	-	-	Beta-lactamase
DEMHKHKO_01421	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
DEMHKHKO_01422	8.31e-139	-	-	-	-	-	-	-	-
DEMHKHKO_01423	7.62e-97	-	-	-	-	-	-	-	-
DEMHKHKO_01425	3.21e-209	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
DEMHKHKO_01426	3.15e-313	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DEMHKHKO_01427	3.93e-99	-	-	-	T	-	-	-	Universal stress protein family
DEMHKHKO_01429	5.62e-316	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
DEMHKHKO_01430	7.89e-245	mocA	-	-	S	-	-	-	Oxidoreductase
DEMHKHKO_01431	6.22e-43	cspP	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
DEMHKHKO_01432	7.34e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
DEMHKHKO_01433	2.22e-185	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
DEMHKHKO_01434	5.63e-196	gntR	-	-	K	-	-	-	rpiR family
DEMHKHKO_01435	2.87e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
DEMHKHKO_01436	7.06e-307	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DEMHKHKO_01437	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
DEMHKHKO_01438	2.26e-129	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DEMHKHKO_01439	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DEMHKHKO_01440	1.59e-242	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
DEMHKHKO_01441	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DEMHKHKO_01442	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
DEMHKHKO_01443	5.11e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DEMHKHKO_01444	9.48e-263	camS	-	-	S	-	-	-	sex pheromone
DEMHKHKO_01445	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DEMHKHKO_01446	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
DEMHKHKO_01447	1.39e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DEMHKHKO_01448	1.13e-120	yebE	-	-	S	-	-	-	UPF0316 protein
DEMHKHKO_01449	2.01e-134	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
DEMHKHKO_01450	1.97e-145	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
DEMHKHKO_01451	7.78e-235	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
DEMHKHKO_01452	5.44e-159	-	-	-	T	-	-	-	EAL domain
DEMHKHKO_01453	8.04e-190	-	3.1.3.23	-	S	ko:K07757	-	ko00000,ko01000	Sucrose-6F-phosphate phosphohydrolase
DEMHKHKO_01454	1.21e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DEMHKHKO_01455	1.46e-263	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
DEMHKHKO_01456	3.38e-70	-	-	-	-	-	-	-	-
DEMHKHKO_01457	2.49e-95	-	-	-	-	-	-	-	-
DEMHKHKO_01458	2.87e-168	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
DEMHKHKO_01459	7.08e-197	-	-	-	G	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
DEMHKHKO_01460	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DEMHKHKO_01461	6.37e-186	-	-	-	-	-	-	-	-
DEMHKHKO_01463	5.45e-94	spx1	-	-	P	ko:K16509	-	ko00000	ArsC family
DEMHKHKO_01464	3.88e-46	-	-	-	-	-	-	-	-
DEMHKHKO_01465	1.71e-116	-	-	-	V	-	-	-	VanZ like family
DEMHKHKO_01466	3.49e-315	-	-	-	EGP	-	-	-	Major Facilitator
DEMHKHKO_01467	4.45e-226	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
DEMHKHKO_01468	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DEMHKHKO_01469	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
DEMHKHKO_01470	7.8e-196	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
DEMHKHKO_01471	3.68e-107	-	-	-	K	-	-	-	Transcriptional regulator
DEMHKHKO_01472	1.36e-27	-	-	-	-	-	-	-	-
DEMHKHKO_01473	1.79e-287	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
DEMHKHKO_01474	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
DEMHKHKO_01475	5.47e-198	ribC1	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
DEMHKHKO_01476	0.0	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
DEMHKHKO_01477	3.45e-231	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
DEMHKHKO_01478	5.01e-229	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
DEMHKHKO_01479	0.0	oatA	-	-	I	-	-	-	Acyltransferase
DEMHKHKO_01480	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
DEMHKHKO_01481	1.55e-89	-	-	-	O	-	-	-	OsmC-like protein
DEMHKHKO_01482	3.8e-61	-	-	-	-	-	-	-	-
DEMHKHKO_01483	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
DEMHKHKO_01484	6.12e-115	-	-	-	-	-	-	-	-
DEMHKHKO_01485	1.23e-189	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
DEMHKHKO_01486	7.48e-96	-	-	-	F	-	-	-	Nudix hydrolase
DEMHKHKO_01487	1.48e-27	-	-	-	-	-	-	-	-
DEMHKHKO_01488	2.02e-106	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
DEMHKHKO_01489	8.84e-18	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
DEMHKHKO_01490	1.01e-188	-	-	-	-	-	-	-	-
DEMHKHKO_01491	1.94e-95	gph1	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant
DEMHKHKO_01492	1.05e-234	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
DEMHKHKO_01493	2.07e-217	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DEMHKHKO_01494	1.28e-54	-	-	-	-	-	-	-	-
DEMHKHKO_01496	2.3e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DEMHKHKO_01497	3.39e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
DEMHKHKO_01498	3.14e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DEMHKHKO_01499	1.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DEMHKHKO_01500	7.04e-108	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
DEMHKHKO_01501	7.77e-197	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
DEMHKHKO_01502	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
DEMHKHKO_01503	4.87e-180	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
DEMHKHKO_01504	9.38e-317	steT	-	-	E	ko:K03294	-	ko00000	amino acid
DEMHKHKO_01505	6.26e-96	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
DEMHKHKO_01506	8.87e-191	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
DEMHKHKO_01507	7.26e-92	-	-	-	K	-	-	-	MarR family
DEMHKHKO_01508	3.22e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
DEMHKHKO_01509	2.93e-109	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
DEMHKHKO_01510	1.81e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DEMHKHKO_01511	5.95e-300	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DEMHKHKO_01512	4.6e-102	rppH3	-	-	F	-	-	-	NUDIX domain
DEMHKHKO_01513	3.5e-64	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
DEMHKHKO_01514	1.61e-36	-	-	-	-	-	-	-	-
DEMHKHKO_01515	1.35e-165	pgm3	-	-	G	-	-	-	Phosphoglycerate mutase family
DEMHKHKO_01516	2.07e-161	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
DEMHKHKO_01517	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
DEMHKHKO_01518	4.16e-227	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
DEMHKHKO_01519	4.51e-143	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
DEMHKHKO_01520	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
DEMHKHKO_01521	8.45e-211	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
DEMHKHKO_01522	1.22e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
DEMHKHKO_01523	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
DEMHKHKO_01525	3.56e-171	spoVK	-	-	O	ko:K06413	-	ko00000	ATPase family associated with various cellular activities (AAA)
DEMHKHKO_01527	9.16e-61	-	-	-	L	-	-	-	Helix-turn-helix domain
DEMHKHKO_01528	8.56e-38	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
DEMHKHKO_01529	6.67e-30	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
DEMHKHKO_01530	1.66e-96	-	-	-	-	-	-	-	-
DEMHKHKO_01531	1.08e-71	-	-	-	-	-	-	-	-
DEMHKHKO_01532	1.37e-83	-	-	-	K	-	-	-	Helix-turn-helix domain
DEMHKHKO_01533	0.0	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
DEMHKHKO_01534	0.0	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
DEMHKHKO_01535	2.54e-225	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
DEMHKHKO_01536	3.72e-145	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
DEMHKHKO_01537	7.32e-292	sat	2.7.7.4	-	H	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
DEMHKHKO_01538	0.0	-	-	-	S	-	-	-	Protein conserved in bacteria
DEMHKHKO_01539	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DEMHKHKO_01540	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
DEMHKHKO_01541	8.01e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
DEMHKHKO_01542	4.91e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
DEMHKHKO_01543	3.89e-237	-	-	-	-	-	-	-	-
DEMHKHKO_01544	9.03e-16	-	-	-	-	-	-	-	-
DEMHKHKO_01545	4.29e-87	-	-	-	-	-	-	-	-
DEMHKHKO_01548	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
DEMHKHKO_01549	7.12e-62	-	-	-	-	-	-	-	-
DEMHKHKO_01550	8.82e-119	-	-	-	-	-	-	-	-
DEMHKHKO_01551	2.2e-111	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
DEMHKHKO_01552	1.23e-145	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DEMHKHKO_01553	4.56e-78	-	-	-	-	-	-	-	-
DEMHKHKO_01554	5.37e-74	-	-	-	-	-	-	-	-
DEMHKHKO_01555	9.01e-179	agrA	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
DEMHKHKO_01556	2.08e-283	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
DEMHKHKO_01557	7.83e-140	-	-	-	-	-	-	-	-
DEMHKHKO_01558	1.89e-189	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
DEMHKHKO_01559	9.36e-205	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
DEMHKHKO_01560	1.64e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
DEMHKHKO_01561	5.2e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
DEMHKHKO_01562	6.96e-198	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DEMHKHKO_01564	2.57e-226	-	-	-	K	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
DEMHKHKO_01565	3.06e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
DEMHKHKO_01566	3.34e-160	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
DEMHKHKO_01568	9.96e-166	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
DEMHKHKO_01569	3.55e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
DEMHKHKO_01570	2.07e-155	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
DEMHKHKO_01571	5.01e-229	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
DEMHKHKO_01572	3.05e-193	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DEMHKHKO_01573	1.13e-221	ugpA	-	-	U	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DEMHKHKO_01574	2.92e-258	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
DEMHKHKO_01575	2.16e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
DEMHKHKO_01576	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
DEMHKHKO_01577	3.03e-193	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DEMHKHKO_01578	5.04e-176	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
DEMHKHKO_01579	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
DEMHKHKO_01580	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
DEMHKHKO_01581	3.58e-161	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
DEMHKHKO_01582	3.03e-122	mraW1	-	-	J	-	-	-	Putative rRNA methylase
DEMHKHKO_01583	9.32e-40	-	-	-	-	-	-	-	-
DEMHKHKO_01584	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
DEMHKHKO_01585	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
DEMHKHKO_01586	0.0	-	-	-	S	-	-	-	Pfam Methyltransferase
DEMHKHKO_01587	1.21e-185	-	-	-	N	-	-	-	Cell shape-determining protein MreB
DEMHKHKO_01588	1.37e-60	-	-	-	N	-	-	-	Cell shape-determining protein MreB
DEMHKHKO_01589	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
DEMHKHKO_01590	2.78e-273	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DEMHKHKO_01591	3.35e-157	-	-	-	-	-	-	-	-
DEMHKHKO_01592	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
DEMHKHKO_01593	2.75e-216	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
DEMHKHKO_01594	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
DEMHKHKO_01595	6.21e-241	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
DEMHKHKO_01596	2.19e-291	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
DEMHKHKO_01598	3.47e-134	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
DEMHKHKO_01599	2.98e-46	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
DEMHKHKO_01600	1.58e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DEMHKHKO_01601	1.25e-124	-	-	-	-	-	-	-	-
DEMHKHKO_01602	1.5e-42	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
DEMHKHKO_01603	3.26e-119	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
DEMHKHKO_01614	7.47e-24	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
DEMHKHKO_01615	1.5e-150	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
DEMHKHKO_01616	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
DEMHKHKO_01617	2.02e-131	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC transporter permease
DEMHKHKO_01618	6.07e-117	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
DEMHKHKO_01619	5.3e-202	dkgB	-	-	S	-	-	-	reductase
DEMHKHKO_01620	1.05e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DEMHKHKO_01621	1.2e-91	-	-	-	-	-	-	-	-
DEMHKHKO_01622	2.32e-43	ygzD	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
DEMHKHKO_01623	3.16e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DEMHKHKO_01624	1.82e-220	-	-	-	P	-	-	-	Major Facilitator Superfamily
DEMHKHKO_01625	3.91e-283	-	-	-	C	-	-	-	FAD dependent oxidoreductase
DEMHKHKO_01626	7.02e-126	-	-	-	K	-	-	-	Helix-turn-helix domain
DEMHKHKO_01627	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
DEMHKHKO_01628	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DEMHKHKO_01629	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
DEMHKHKO_01630	5.33e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DEMHKHKO_01631	1.76e-280	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
DEMHKHKO_01632	1.21e-111	-	-	-	-	-	-	-	-
DEMHKHKO_01633	4.81e-76	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
DEMHKHKO_01634	5.92e-67	-	-	-	-	-	-	-	-
DEMHKHKO_01635	2.37e-123	-	-	-	-	-	-	-	-
DEMHKHKO_01636	1.73e-89	-	-	-	-	-	-	-	-
DEMHKHKO_01637	2.41e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
DEMHKHKO_01638	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
DEMHKHKO_01639	1.82e-126	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
DEMHKHKO_01640	2.13e-124	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
DEMHKHKO_01641	7.87e-266	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
DEMHKHKO_01642	2.52e-209	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
DEMHKHKO_01643	6.72e-203	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
DEMHKHKO_01644	1.27e-181	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
DEMHKHKO_01645	7.55e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
DEMHKHKO_01646	6.35e-56	-	-	-	-	-	-	-	-
DEMHKHKO_01647	1.68e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
DEMHKHKO_01648	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
DEMHKHKO_01649	0.0	pts4ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
DEMHKHKO_01650	0.0	pts5ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
DEMHKHKO_01651	2.6e-185	-	-	-	-	-	-	-	-
DEMHKHKO_01652	1.21e-94	tagD	2.7.7.15, 2.7.7.39	-	IM	ko:K00968,ko:K00980	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Glycerol-3-phosphate cytidylyltransferase
DEMHKHKO_01653	5.71e-306	tagB	2.7.8.12, 2.7.8.45	-	M	ko:K09809,ko:K21591	-	ko00000,ko01000	glycerophosphotransferase
DEMHKHKO_01654	0.0	tagF2	2.7.8.12	-	H	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
DEMHKHKO_01655	3.37e-129	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
DEMHKHKO_01656	2.73e-92	-	-	-	-	-	-	-	-
DEMHKHKO_01657	8.9e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
DEMHKHKO_01658	8.62e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DEMHKHKO_01659	4.02e-301	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
DEMHKHKO_01660	4.5e-150	-	-	-	-	-	-	-	-
DEMHKHKO_01661	6.37e-52	-	-	-	-	-	-	-	-
DEMHKHKO_01662	3.13e-55	-	-	-	-	-	-	-	-
DEMHKHKO_01663	0.0	ydiC	-	-	EGP	-	-	-	Major Facilitator
DEMHKHKO_01664	2.2e-86	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
DEMHKHKO_01665	1.72e-315	hpk2	-	-	T	-	-	-	Histidine kinase
DEMHKHKO_01666	2.58e-163	rrp2	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
DEMHKHKO_01667	9.86e-65	-	-	-	-	-	-	-	-
DEMHKHKO_01668	2.78e-167	yidA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
DEMHKHKO_01669	6.86e-311	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DEMHKHKO_01670	1.6e-73	-	-	-	-	-	-	-	-
DEMHKHKO_01671	2.87e-56	-	-	-	-	-	-	-	-
DEMHKHKO_01672	5.06e-236	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
DEMHKHKO_01673	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
DEMHKHKO_01674	1.49e-63	-	-	-	-	-	-	-	-
DEMHKHKO_01675	2.04e-158	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
DEMHKHKO_01676	1.17e-135	-	-	-	K	-	-	-	transcriptional regulator
DEMHKHKO_01677	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
DEMHKHKO_01678	1.96e-137	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
DEMHKHKO_01679	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
DEMHKHKO_01680	4.32e-294	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
DEMHKHKO_01681	4.87e-156	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
DEMHKHKO_01682	1.13e-171	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
DEMHKHKO_01683	4.75e-157	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DEMHKHKO_01684	4.15e-191	yxeH	-	-	S	-	-	-	hydrolase
DEMHKHKO_01685	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
DEMHKHKO_01686	1.14e-202	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
DEMHKHKO_01687	2.87e-101	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
DEMHKHKO_01688	2.96e-89	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
DEMHKHKO_01689	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
DEMHKHKO_01690	5.84e-312	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DEMHKHKO_01691	2.28e-290	sdaC	-	-	E	ko:K03837	-	ko00000,ko02000	amino acid
DEMHKHKO_01692	7.51e-159	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
DEMHKHKO_01693	2.81e-202	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
DEMHKHKO_01694	6.59e-170	-	-	-	S	-	-	-	YheO-like PAS domain
DEMHKHKO_01695	4.01e-36	-	-	-	-	-	-	-	-
DEMHKHKO_01696	2.08e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DEMHKHKO_01697	1.26e-305	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DEMHKHKO_01698	1.91e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
DEMHKHKO_01699	2.57e-274	-	-	-	J	-	-	-	translation release factor activity
DEMHKHKO_01700	3.14e-164	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
DEMHKHKO_01701	5.35e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
DEMHKHKO_01702	1.6e-194	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
DEMHKHKO_01703	1.84e-189	-	-	-	-	-	-	-	-
DEMHKHKO_01704	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
DEMHKHKO_01705	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
DEMHKHKO_01706	9.32e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
DEMHKHKO_01707	4.79e-273	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DEMHKHKO_01708	2.58e-85	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
DEMHKHKO_01709	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
DEMHKHKO_01710	1.37e-248	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	ABC transporter, substratebinding protein
DEMHKHKO_01711	3.03e-202	-	-	-	U	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DEMHKHKO_01712	5.79e-171	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
DEMHKHKO_01713	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
DEMHKHKO_01714	7.48e-260	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
DEMHKHKO_01715	8.87e-245	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DEMHKHKO_01716	2.29e-292	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DEMHKHKO_01717	2.36e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
DEMHKHKO_01718	3.52e-273	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
DEMHKHKO_01719	1.52e-240	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DEMHKHKO_01720	1.3e-110	queT	-	-	S	-	-	-	QueT transporter
DEMHKHKO_01721	1.4e-147	-	-	-	S	-	-	-	(CBS) domain
DEMHKHKO_01722	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
DEMHKHKO_01723	2.79e-226	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
DEMHKHKO_01724	1.43e-129	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
DEMHKHKO_01725	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DEMHKHKO_01726	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
DEMHKHKO_01727	7.72e-57	yabO	-	-	J	-	-	-	S4 domain protein
DEMHKHKO_01729	2.02e-83	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
DEMHKHKO_01730	1.07e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
DEMHKHKO_01731	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
DEMHKHKO_01732	4.3e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
DEMHKHKO_01733	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DEMHKHKO_01734	1.93e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DEMHKHKO_01735	5.33e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DEMHKHKO_01736	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
DEMHKHKO_01737	1.03e-40	-	-	-	-	-	-	-	-
DEMHKHKO_01738	1.76e-162	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
DEMHKHKO_01739	2.09e-124	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
DEMHKHKO_01740	2.1e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
DEMHKHKO_01741	1.28e-45	-	-	-	-	-	-	-	-
DEMHKHKO_01742	2.9e-194	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
DEMHKHKO_01743	1.66e-247	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
DEMHKHKO_01744	1.52e-135	-	-	-	GM	-	-	-	NAD(P)H-binding
DEMHKHKO_01745	1.51e-200	-	-	-	K	-	-	-	LysR substrate binding domain
DEMHKHKO_01746	6.09e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
DEMHKHKO_01747	7.44e-143	pgm8	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
DEMHKHKO_01748	2.81e-64	-	-	-	-	-	-	-	-
DEMHKHKO_01749	9.76e-50	-	-	-	-	-	-	-	-
DEMHKHKO_01750	1.04e-110	yvbK	-	-	K	-	-	-	GNAT family
DEMHKHKO_01751	4.86e-111	-	-	-	-	-	-	-	-
DEMHKHKO_01753	1.03e-150	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
DEMHKHKO_01754	3.18e-141	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
DEMHKHKO_01755	1.19e-150	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DEMHKHKO_01757	1.74e-156	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DEMHKHKO_01758	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
DEMHKHKO_01759	4.87e-298	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
DEMHKHKO_01760	5.19e-103	-	-	-	K	-	-	-	transcriptional regulator, MerR family
DEMHKHKO_01761	4.77e-100	yphH	-	-	S	-	-	-	Cupin domain
DEMHKHKO_01762	4.72e-72	cmd	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
DEMHKHKO_01763	6.27e-166	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
DEMHKHKO_01764	3.91e-269	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
DEMHKHKO_01765	1.65e-212	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DEMHKHKO_01766	6.5e-119	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
DEMHKHKO_01767	2.24e-78	-	-	-	M	-	-	-	LysM domain
DEMHKHKO_01769	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
DEMHKHKO_01770	0.0	tagE5	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
DEMHKHKO_01771	5.9e-194	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
DEMHKHKO_01772	2.17e-222	-	-	-	S	-	-	-	Conserved hypothetical protein 698
DEMHKHKO_01773	8.99e-133	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
DEMHKHKO_01774	4.03e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
DEMHKHKO_01775	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
DEMHKHKO_01776	7.22e-163	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
DEMHKHKO_01777	4.32e-261	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
DEMHKHKO_01778	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
DEMHKHKO_01779	2.11e-199	mleP3	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
DEMHKHKO_01780	7.1e-152	-	-	-	S	-	-	-	Membrane
DEMHKHKO_01781	9.35e-257	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
DEMHKHKO_01782	3.55e-127	ywjB	-	-	H	-	-	-	RibD C-terminal domain
DEMHKHKO_01783	5.72e-238	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
DEMHKHKO_01784	2.76e-117	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
DEMHKHKO_01785	1.18e-155	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DEMHKHKO_01786	1.2e-240	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
DEMHKHKO_01787	1.86e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
DEMHKHKO_01788	3.41e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DEMHKHKO_01789	9.38e-189	-	-	-	KT	-	-	-	helix_turn_helix, mercury resistance
DEMHKHKO_01790	3.38e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
DEMHKHKO_01791	1.04e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
DEMHKHKO_01792	3.84e-185	-	-	-	S	-	-	-	Peptidase_C39 like family
DEMHKHKO_01793	1.08e-229	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
DEMHKHKO_01794	1.27e-143	-	-	-	-	-	-	-	-
DEMHKHKO_01795	1.21e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DEMHKHKO_01796	1.97e-110	-	-	-	S	-	-	-	Pfam:DUF3816
DEMHKHKO_01797	0.0	-	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
DEMHKHKO_01798	0.0	cadA	-	-	P	-	-	-	P-type ATPase
DEMHKHKO_01800	9.45e-160	-	-	-	S	-	-	-	YjbR
DEMHKHKO_01801	4.04e-37	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
DEMHKHKO_01802	3.23e-215	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
DEMHKHKO_01803	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DEMHKHKO_01804	1.44e-255	glmS2	-	-	M	-	-	-	SIS domain
DEMHKHKO_01805	2.07e-35	-	-	-	S	-	-	-	Belongs to the LOG family
DEMHKHKO_01806	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
DEMHKHKO_01807	3.98e-315	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
DEMHKHKO_01808	5.85e-92	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
DEMHKHKO_01809	5.38e-92	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
DEMHKHKO_01810	4.75e-112	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
DEMHKHKO_01811	1.07e-206	-	-	-	GM	-	-	-	NmrA-like family
DEMHKHKO_01812	2.14e-86	-	-	-	K	ko:K22296	-	ko00000,ko03000	Winged helix DNA-binding domain
DEMHKHKO_01813	9.97e-94	spxA	-	-	P	ko:K16509	-	ko00000	ArsC family
DEMHKHKO_01814	3.46e-87	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
DEMHKHKO_01815	1.7e-70	-	-	-	-	-	-	-	-
DEMHKHKO_01816	4.98e-275	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
DEMHKHKO_01817	2.11e-82	-	-	-	-	-	-	-	-
DEMHKHKO_01818	1.36e-112	-	-	-	-	-	-	-	-
DEMHKHKO_01819	4.58e-103	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
DEMHKHKO_01820	3.78e-73	-	-	-	-	-	-	-	-
DEMHKHKO_01821	4.79e-21	-	-	-	-	-	-	-	-
DEMHKHKO_01822	3.57e-150	-	-	-	GM	-	-	-	NmrA-like family
DEMHKHKO_01823	2.52e-107	-	-	-	S	ko:K02348	-	ko00000	GNAT family
DEMHKHKO_01824	9.43e-203	-	-	-	EG	-	-	-	EamA-like transporter family
DEMHKHKO_01825	2.66e-155	-	-	-	S	-	-	-	membrane
DEMHKHKO_01826	1.47e-144	-	-	-	S	-	-	-	VIT family
DEMHKHKO_01827	4.38e-243	pva2	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
DEMHKHKO_01828	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
DEMHKHKO_01829	8.01e-97	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
DEMHKHKO_01830	4.26e-54	-	-	-	-	-	-	-	-
DEMHKHKO_01831	3.43e-96	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
DEMHKHKO_01832	8.8e-315	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
DEMHKHKO_01833	7.21e-35	-	-	-	-	-	-	-	-
DEMHKHKO_01834	2.55e-65	-	-	-	-	-	-	-	-
DEMHKHKO_01835	2.51e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF1398)
DEMHKHKO_01836	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
DEMHKHKO_01837	1.77e-282	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
DEMHKHKO_01838	9.92e-230	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
DEMHKHKO_01839	6.1e-101	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
DEMHKHKO_01840	1.14e-110	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
DEMHKHKO_01841	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
DEMHKHKO_01842	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
DEMHKHKO_01843	2.3e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
DEMHKHKO_01844	1.36e-209	yvgN	-	-	C	-	-	-	Aldo keto reductase
DEMHKHKO_01845	2.57e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
DEMHKHKO_01846	1.7e-101	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
DEMHKHKO_01847	1.5e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
DEMHKHKO_01848	2.69e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
DEMHKHKO_01849	5.94e-118	ymdB	-	-	S	-	-	-	Macro domain protein
DEMHKHKO_01850	6.47e-124	-	-	-	K	ko:K22041	-	ko00000,ko03000	transcriptional regulator
DEMHKHKO_01851	1.58e-66	-	-	-	-	-	-	-	-
DEMHKHKO_01852	2.41e-212	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
DEMHKHKO_01853	0.0	-	-	-	-	-	-	-	-
DEMHKHKO_01854	2.08e-161	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
DEMHKHKO_01855	5.03e-43	-	-	-	-	-	-	-	-
DEMHKHKO_01856	2.21e-178	-	-	-	Q	-	-	-	Methyltransferase
DEMHKHKO_01857	2.84e-75	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
DEMHKHKO_01858	1.66e-269	-	-	-	EGP	-	-	-	Major facilitator Superfamily
DEMHKHKO_01859	3.58e-129	-	-	-	K	-	-	-	Helix-turn-helix domain
DEMHKHKO_01860	1.52e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DEMHKHKO_01861	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
DEMHKHKO_01862	1.84e-67	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
DEMHKHKO_01863	7.09e-180	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
DEMHKHKO_01864	8.34e-228	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
DEMHKHKO_01865	6.62e-62	-	-	-	-	-	-	-	-
DEMHKHKO_01866	1.55e-311	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DEMHKHKO_01867	3.02e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
DEMHKHKO_01868	4.24e-218	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
DEMHKHKO_01869	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
DEMHKHKO_01870	0.0	-	3.1.4.53	-	S	ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
DEMHKHKO_01871	0.0	cps4J	-	-	S	-	-	-	MatE
DEMHKHKO_01872	4.82e-228	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
DEMHKHKO_01873	1.91e-297	-	-	-	-	-	-	-	-
DEMHKHKO_01874	7.88e-48	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
DEMHKHKO_01875	1.82e-132	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
DEMHKHKO_01876	1.43e-223	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
DEMHKHKO_01877	3.18e-162	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
DEMHKHKO_01878	8.71e-231	cps4D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
DEMHKHKO_01879	5.54e-189	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
DEMHKHKO_01880	2.02e-156	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
DEMHKHKO_01881	8.45e-162	epsB	-	-	M	-	-	-	biosynthesis protein
DEMHKHKO_01882	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
DEMHKHKO_01883	3.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DEMHKHKO_01884	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
DEMHKHKO_01885	5.12e-31	-	-	-	-	-	-	-	-
DEMHKHKO_01886	6.47e-95	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
DEMHKHKO_01887	1.3e-65	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
DEMHKHKO_01888	9.6e-143	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
DEMHKHKO_01889	7.8e-300	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DEMHKHKO_01890	3.21e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
DEMHKHKO_01891	4.38e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DEMHKHKO_01892	9.34e-201	-	-	-	S	-	-	-	Tetratricopeptide repeat
DEMHKHKO_01893	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DEMHKHKO_01894	1.29e-200	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DEMHKHKO_01895	1.8e-135	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
DEMHKHKO_01896	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DEMHKHKO_01897	1.18e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
DEMHKHKO_01898	8.43e-240	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
DEMHKHKO_01899	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
DEMHKHKO_01900	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
DEMHKHKO_01901	2.1e-161	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
DEMHKHKO_01902	1.05e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
DEMHKHKO_01903	7.04e-108	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DEMHKHKO_01904	8.61e-132	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
DEMHKHKO_01905	1.91e-66	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
DEMHKHKO_01906	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DEMHKHKO_01907	1.45e-260	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
DEMHKHKO_01908	0.0	-	-	-	-	-	-	-	-
DEMHKHKO_01909	1.56e-262	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
DEMHKHKO_01910	4.1e-223	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
DEMHKHKO_01911	3.22e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
DEMHKHKO_01912	7.24e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
DEMHKHKO_01913	1.74e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
DEMHKHKO_01914	7.01e-76	ftsL	-	-	D	-	-	-	Cell division protein FtsL
DEMHKHKO_01915	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
DEMHKHKO_01916	2.81e-231	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DEMHKHKO_01917	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DEMHKHKO_01918	2.04e-252	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DEMHKHKO_01919	2.34e-208	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
DEMHKHKO_01920	3.55e-312	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
DEMHKHKO_01921	9.39e-295	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DEMHKHKO_01922	1.56e-93	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
DEMHKHKO_01923	6.45e-49	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
DEMHKHKO_01924	2.06e-187	ylmH	-	-	S	-	-	-	S4 domain protein
DEMHKHKO_01925	6.52e-124	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
DEMHKHKO_01926	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DEMHKHKO_01927	3.46e-242	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DEMHKHKO_01928	3.51e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
DEMHKHKO_01929	7.74e-47	-	-	-	-	-	-	-	-
DEMHKHKO_01930	5.85e-158	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DEMHKHKO_01931	8.09e-275	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
DEMHKHKO_01932	4.94e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
DEMHKHKO_01933	1.53e-284	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
DEMHKHKO_01934	9.64e-307	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
DEMHKHKO_01935	4.64e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
DEMHKHKO_01936	4.17e-153	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
DEMHKHKO_01937	2.02e-247	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
DEMHKHKO_01938	0.0	-	-	-	N	-	-	-	domain, Protein
DEMHKHKO_01939	2.41e-157	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
DEMHKHKO_01940	1.02e-155	-	-	-	S	-	-	-	repeat protein
DEMHKHKO_01941	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
DEMHKHKO_01942	5.35e-220	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DEMHKHKO_01943	2.62e-168	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
DEMHKHKO_01944	2.16e-39	-	-	-	-	-	-	-	-
DEMHKHKO_01945	3.45e-240	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
DEMHKHKO_01946	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DEMHKHKO_01947	4.86e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
DEMHKHKO_01948	6.45e-111	-	-	-	-	-	-	-	-
DEMHKHKO_01949	3.95e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DEMHKHKO_01950	1.21e-268	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
DEMHKHKO_01951	8.65e-228	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
DEMHKHKO_01952	2.36e-285	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
DEMHKHKO_01953	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
DEMHKHKO_01954	2.15e-209	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
DEMHKHKO_01955	2.64e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
DEMHKHKO_01956	7.1e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
DEMHKHKO_01957	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
DEMHKHKO_01958	4.84e-227	-	-	-	-	-	-	-	-
DEMHKHKO_01959	4.08e-101	-	-	-	K	-	-	-	MerR family regulatory protein
DEMHKHKO_01960	7.54e-200	-	-	-	GM	-	-	-	NmrA-like family
DEMHKHKO_01961	0.0	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
DEMHKHKO_01962	1.25e-164	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
DEMHKHKO_01964	2.95e-100	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
DEMHKHKO_01965	8.44e-304	-	-	-	S	-	-	-	module of peptide synthetase
DEMHKHKO_01966	1.16e-135	-	-	-	-	-	-	-	-
DEMHKHKO_01967	1.55e-114	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
DEMHKHKO_01968	1.28e-77	-	-	-	S	-	-	-	Enterocin A Immunity
DEMHKHKO_01969	6.46e-49	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
DEMHKHKO_01970	7.47e-77	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
DEMHKHKO_01971	1.33e-100	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
DEMHKHKO_01972	2.8e-135	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
DEMHKHKO_01973	4.14e-84	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
DEMHKHKO_01974	2.88e-164	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
DEMHKHKO_01975	1.56e-185	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
DEMHKHKO_01976	1.03e-34	-	-	-	-	-	-	-	-
DEMHKHKO_01977	7.02e-151	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
DEMHKHKO_01978	0.0	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
DEMHKHKO_01979	2.85e-210	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
DEMHKHKO_01980	9.07e-233	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
DEMHKHKO_01981	1.49e-253	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
DEMHKHKO_01982	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
DEMHKHKO_01983	2.05e-72	-	-	-	S	-	-	-	Enterocin A Immunity
DEMHKHKO_01984	3.66e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DEMHKHKO_01985	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DEMHKHKO_01986	4.17e-235	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DEMHKHKO_01987	1.02e-187	ptp2	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
DEMHKHKO_01988	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DEMHKHKO_01990	4.62e-107	-	-	-	-	-	-	-	-
DEMHKHKO_01991	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
DEMHKHKO_01993	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
DEMHKHKO_01994	1.07e-211	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DEMHKHKO_01995	3.1e-228	ydbI	-	-	K	-	-	-	AI-2E family transporter
DEMHKHKO_01996	1.38e-275	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
DEMHKHKO_01997	1.63e-77	-	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
DEMHKHKO_01998	1.97e-60	qacH	-	-	U	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
DEMHKHKO_01999	2.94e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
DEMHKHKO_02000	7.27e-73	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
DEMHKHKO_02001	1.3e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
DEMHKHKO_02002	8.03e-28	-	-	-	-	-	-	-	-
DEMHKHKO_02003	3.91e-124	tag2	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
DEMHKHKO_02004	5.59e-271	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
DEMHKHKO_02005	2.01e-134	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
DEMHKHKO_02006	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
DEMHKHKO_02007	1.8e-134	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
DEMHKHKO_02008	1.59e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
DEMHKHKO_02009	9.61e-84	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DEMHKHKO_02010	4.26e-109	cvpA	-	-	S	-	-	-	Colicin V production protein
DEMHKHKO_02011	5.61e-216	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
DEMHKHKO_02012	8.83e-317	-	-	-	EGP	-	-	-	Major Facilitator
DEMHKHKO_02014	4.54e-54	-	-	-	-	-	-	-	-
DEMHKHKO_02015	2.69e-316	dinF	-	-	V	-	-	-	MatE
DEMHKHKO_02016	1.79e-42	-	-	-	-	-	-	-	-
DEMHKHKO_02019	8.2e-102	yybD	-	-	S	ko:K02348	-	ko00000	Acetyltransferase (GNAT) domain
DEMHKHKO_02020	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
DEMHKHKO_02021	4.64e-106	-	-	-	-	-	-	-	-
DEMHKHKO_02022	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
DEMHKHKO_02023	1.04e-136	-	-	-	-	-	-	-	-
DEMHKHKO_02024	0.0	celR	-	-	K	-	-	-	PRD domain
DEMHKHKO_02025	1.34e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
DEMHKHKO_02026	2.37e-68	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
DEMHKHKO_02027	4.9e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DEMHKHKO_02028	1.71e-277	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DEMHKHKO_02029	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DEMHKHKO_02030	3.5e-271	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
DEMHKHKO_02031	2.34e-146	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
DEMHKHKO_02032	1.65e-46	dltC2	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DEMHKHKO_02033	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	Alanine-glyoxylate amino-transferase
DEMHKHKO_02034	8.08e-133	argO	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
DEMHKHKO_02035	5.58e-271	arcT	-	-	E	-	-	-	Aminotransferase
DEMHKHKO_02036	2.07e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
DEMHKHKO_02037	2.43e-18	-	-	-	-	-	-	-	-
DEMHKHKO_02038	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
DEMHKHKO_02039	9.94e-71	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
DEMHKHKO_02040	4.47e-296	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
DEMHKHKO_02041	0.0	yhaN	-	-	L	-	-	-	AAA domain
DEMHKHKO_02042	1.03e-240	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
DEMHKHKO_02043	1.05e-272	-	-	-	-	-	-	-	-
DEMHKHKO_02044	2.41e-233	-	-	-	M	-	-	-	Peptidase family S41
DEMHKHKO_02045	1.09e-225	-	-	-	K	-	-	-	LysR substrate binding domain
DEMHKHKO_02046	9.9e-144	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
DEMHKHKO_02047	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
DEMHKHKO_02048	4.43e-129	-	-	-	-	-	-	-	-
DEMHKHKO_02049	1.17e-100	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
DEMHKHKO_02050	1.15e-235	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
DEMHKHKO_02051	7.78e-20	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DEMHKHKO_02052	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DEMHKHKO_02053	4.29e-26	-	-	-	S	-	-	-	NUDIX domain
DEMHKHKO_02054	1.36e-126	-	-	-	S	-	-	-	membrane
DEMHKHKO_02055	4.26e-218	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DEMHKHKO_02056	2.61e-95	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
DEMHKHKO_02057	2.08e-284	ribA	3.5.4.25, 4.1.99.12	-	H	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
DEMHKHKO_02058	1.23e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
DEMHKHKO_02059	5.21e-137	-	-	-	S	ko:K09962	-	ko00000	Nucleotidyltransferase
DEMHKHKO_02060	1.96e-137	-	-	-	-	-	-	-	-
DEMHKHKO_02061	3.3e-151	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
DEMHKHKO_02062	1.08e-95	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DEMHKHKO_02063	1.36e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
DEMHKHKO_02064	1.23e-57	-	-	-	S	-	-	-	Cupredoxin-like domain
DEMHKHKO_02065	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
DEMHKHKO_02066	6.8e-272	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
DEMHKHKO_02067	4.2e-286	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
DEMHKHKO_02068	4.8e-86	lysM	-	-	M	-	-	-	LysM domain
DEMHKHKO_02069	0.0	-	-	-	E	-	-	-	Amino Acid
DEMHKHKO_02070	1.43e-184	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DEMHKHKO_02071	1.97e-92	-	-	-	-	-	-	-	-
DEMHKHKO_02073	2.96e-209	yhxD	-	-	IQ	-	-	-	KR domain
DEMHKHKO_02074	3.23e-290	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
DEMHKHKO_02076	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
DEMHKHKO_02077	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DEMHKHKO_02078	2.31e-277	-	-	-	-	-	-	-	-
DEMHKHKO_02079	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
DEMHKHKO_02080	7.43e-97	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
DEMHKHKO_02081	3.55e-281	-	-	-	T	-	-	-	diguanylate cyclase
DEMHKHKO_02082	1.92e-155	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
DEMHKHKO_02083	3.57e-120	-	-	-	-	-	-	-	-
DEMHKHKO_02084	5.76e-212	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
DEMHKHKO_02085	1.58e-72	nudA	-	-	S	-	-	-	ASCH
DEMHKHKO_02086	5.71e-138	-	-	-	S	-	-	-	SdpI/YhfL protein family
DEMHKHKO_02087	7.94e-126	-	-	-	M	-	-	-	Lysin motif
DEMHKHKO_02088	4.61e-101	-	-	-	M	-	-	-	LysM domain
DEMHKHKO_02089	2.1e-99	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
DEMHKHKO_02090	4.32e-235	-	-	-	GM	-	-	-	Male sterility protein
DEMHKHKO_02091	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DEMHKHKO_02092	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DEMHKHKO_02093	7.47e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DEMHKHKO_02094	3.91e-100	pts23A	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
DEMHKHKO_02095	1.24e-194	-	-	-	K	-	-	-	Helix-turn-helix domain
DEMHKHKO_02096	1.21e-73	-	-	-	-	-	-	-	-
DEMHKHKO_02097	1.58e-204	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
DEMHKHKO_02098	2.03e-84	-	-	-	-	-	-	-	-
DEMHKHKO_02099	0.0	-	-	-	P	-	-	-	Concanavalin A-like lectin/glucanases superfamily
DEMHKHKO_02100	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DEMHKHKO_02101	7.89e-124	-	-	-	P	-	-	-	Cadmium resistance transporter
DEMHKHKO_02102	8.58e-65	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
DEMHKHKO_02103	1.81e-150	-	-	-	S	-	-	-	SNARE associated Golgi protein
DEMHKHKO_02104	7.03e-62	-	-	-	-	-	-	-	-
DEMHKHKO_02105	1.18e-94	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
DEMHKHKO_02106	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
DEMHKHKO_02107	3.35e-157	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DEMHKHKO_02108	2.88e-106	gtcA3	-	-	S	-	-	-	GtrA-like protein
DEMHKHKO_02109	2.81e-167	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
DEMHKHKO_02110	1.75e-47	-	-	-	K	-	-	-	MerR HTH family regulatory protein
DEMHKHKO_02111	2.03e-155	azlC	-	-	E	-	-	-	branched-chain amino acid
DEMHKHKO_02112	3.43e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
DEMHKHKO_02113	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
DEMHKHKO_02114	9.85e-281	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
DEMHKHKO_02115	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DEMHKHKO_02116	0.0	xylP2	-	-	G	-	-	-	symporter
DEMHKHKO_02117	4.24e-246	-	-	-	I	-	-	-	alpha/beta hydrolase fold
DEMHKHKO_02118	3.33e-64	-	-	-	-	-	-	-	-
DEMHKHKO_02119	1.24e-155	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
DEMHKHKO_02120	7.84e-117	-	-	-	K	-	-	-	FR47-like protein
DEMHKHKO_02121	4.18e-163	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
DEMHKHKO_02122	1.89e-277	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
DEMHKHKO_02123	2.26e-243	-	-	-	-	-	-	-	-
DEMHKHKO_02124	2.91e-179	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
DEMHKHKO_02125	5.06e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
DEMHKHKO_02126	9.95e-211	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
DEMHKHKO_02127	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
DEMHKHKO_02128	4.95e-44	-	-	-	L	-	-	-	leucine-zipper of insertion element IS481
DEMHKHKO_02129	9.05e-55	-	-	-	-	-	-	-	-
DEMHKHKO_02130	1.32e-290	-	-	-	L	-	-	-	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DEMHKHKO_02131	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
DEMHKHKO_02132	3.39e-255	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
DEMHKHKO_02133	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
DEMHKHKO_02134	1.64e-149	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DEMHKHKO_02135	4.3e-106	-	-	-	K	-	-	-	Transcriptional regulator
DEMHKHKO_02137	5.68e-266	-	-	-	C	-	-	-	FMN_bind
DEMHKHKO_02138	4.37e-120	-	-	-	C	-	-	-	FMN_bind
DEMHKHKO_02139	3.93e-220	-	-	-	K	-	-	-	Transcriptional regulator
DEMHKHKO_02140	7.39e-54	-	-	-	K	-	-	-	Helix-turn-helix domain
DEMHKHKO_02141	2.56e-60	-	-	-	K	-	-	-	Helix-turn-helix domain
DEMHKHKO_02142	7.45e-180	-	-	-	K	-	-	-	sequence-specific DNA binding
DEMHKHKO_02143	1.73e-113	-	-	-	S	-	-	-	AAA domain
DEMHKHKO_02144	1.42e-08	-	-	-	-	-	-	-	-
DEMHKHKO_02145	5.86e-314	-	-	-	M	-	-	-	MucBP domain
DEMHKHKO_02146	0.0	-	-	-	M	-	-	-	MucBP domain
DEMHKHKO_02147	4.85e-119	XK27_09665	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
DEMHKHKO_02148	3.79e-57	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
DEMHKHKO_02149	4.61e-222	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DEMHKHKO_02150	5.09e-81	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
DEMHKHKO_02151	9.16e-190	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
DEMHKHKO_02152	2.92e-118	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
DEMHKHKO_02153	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
DEMHKHKO_02154	6.48e-135	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
DEMHKHKO_02155	8.68e-118	pts21A	-	-	G	ko:K02755	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
DEMHKHKO_02156	2e-52	-	-	-	S	-	-	-	Cytochrome B5
DEMHKHKO_02157	0.0	-	-	-	-	-	-	-	-
DEMHKHKO_02158	1.01e-167	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
DEMHKHKO_02159	9.55e-205	-	-	-	I	-	-	-	alpha/beta hydrolase fold
DEMHKHKO_02160	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
DEMHKHKO_02161	1.76e-298	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
DEMHKHKO_02162	1.54e-219	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DEMHKHKO_02163	1.35e-264	-	-	-	EGP	-	-	-	Major facilitator Superfamily
DEMHKHKO_02164	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
DEMHKHKO_02165	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
DEMHKHKO_02166	5.69e-191	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
DEMHKHKO_02167	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
DEMHKHKO_02168	2.09e-287	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DEMHKHKO_02169	8.76e-126	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
DEMHKHKO_02170	1.39e-134	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
DEMHKHKO_02171	4.36e-197	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
DEMHKHKO_02172	6.88e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
DEMHKHKO_02173	1.23e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
DEMHKHKO_02174	2.06e-313	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
DEMHKHKO_02179	6.27e-316	-	-	-	EGP	-	-	-	Major Facilitator
DEMHKHKO_02180	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DEMHKHKO_02181	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DEMHKHKO_02183	1.8e-249	-	-	-	C	-	-	-	Aldo/keto reductase family
DEMHKHKO_02184	1.07e-131	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
DEMHKHKO_02185	2.33e-283	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
DEMHKHKO_02186	3.73e-131	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
DEMHKHKO_02187	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
DEMHKHKO_02188	2.1e-33	-	-	-	-	-	-	-	-
DEMHKHKO_02189	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DEMHKHKO_02190	1.89e-254	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
DEMHKHKO_02191	2.62e-76	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
DEMHKHKO_02192	0.0	-	3.6.3.44	-	P	ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
DEMHKHKO_02193	4.63e-24	-	-	-	-	-	-	-	-
DEMHKHKO_02194	1.25e-25	-	-	-	-	-	-	-	-
DEMHKHKO_02195	9.85e-22	-	-	-	-	-	-	-	-
DEMHKHKO_02196	2.69e-23	-	-	-	-	-	-	-	-
DEMHKHKO_02197	9.05e-22	-	-	-	-	-	-	-	-
DEMHKHKO_02198	2.55e-217	inlJ	-	-	M	-	-	-	MucBP domain
DEMHKHKO_02199	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
DEMHKHKO_02200	1.27e-109	-	-	-	K	-	-	-	MarR family
DEMHKHKO_02201	9.28e-58	-	-	-	-	-	-	-	-
DEMHKHKO_02202	1.28e-51	-	-	-	-	-	-	-	-
DEMHKHKO_02203	1.79e-289	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DEMHKHKO_02204	1.1e-06	-	-	-	K	ko:K07727	-	ko00000,ko03000	transcriptional regulator
DEMHKHKO_02207	2.62e-40	-	-	-	-	-	-	-	-
DEMHKHKO_02208	1.5e-187	-	-	-	L	-	-	-	DNA replication protein
DEMHKHKO_02209	0.0	-	-	-	S	-	-	-	Virulence-associated protein E
DEMHKHKO_02210	3.36e-96	-	-	-	-	-	-	-	-
DEMHKHKO_02212	3.24e-62	-	-	-	S	-	-	-	Head-tail joining protein
DEMHKHKO_02213	1.05e-88	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	Phage-associated protein
DEMHKHKO_02214	1.9e-109	terS	-	-	L	-	-	-	Phage terminase, small subunit
DEMHKHKO_02215	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
DEMHKHKO_02217	6.16e-260	-	-	-	S	-	-	-	Phage portal protein
DEMHKHKO_02218	0.0	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
DEMHKHKO_02219	1.75e-48	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
DEMHKHKO_02220	1.02e-80	-	-	-	-	-	-	-	-
DEMHKHKO_02222	1.98e-40	-	-	-	-	-	-	-	-
DEMHKHKO_02224	9.38e-279	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DEMHKHKO_02228	4.23e-19	-	-	-	S	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
DEMHKHKO_02230	2.69e-38	-	-	-	S	-	-	-	TerB N-terminal domain
DEMHKHKO_02231	1.92e-97	-	-	-	E	-	-	-	IrrE N-terminal-like domain
DEMHKHKO_02232	2.67e-80	-	-	-	K	-	-	-	Helix-turn-helix domain
DEMHKHKO_02233	7.19e-51	-	-	-	K	-	-	-	Helix-turn-helix
DEMHKHKO_02235	6.59e-72	-	-	-	-	-	-	-	-
DEMHKHKO_02236	2.15e-110	-	-	-	-	-	-	-	-
DEMHKHKO_02238	8e-70	-	-	-	S	-	-	-	Bacteriophage Mu Gam like protein
DEMHKHKO_02239	6.45e-80	-	-	-	-	-	-	-	-
DEMHKHKO_02240	7.28e-213	-	-	-	L	-	-	-	DnaD domain protein
DEMHKHKO_02241	3.24e-67	-	-	-	-	-	-	-	-
DEMHKHKO_02242	8.15e-167	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DEMHKHKO_02243	1.93e-31	plnF	-	-	-	-	-	-	-
DEMHKHKO_02244	2.59e-19	-	-	-	-	-	-	-	-
DEMHKHKO_02245	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
DEMHKHKO_02246	1.17e-306	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
DEMHKHKO_02247	2.6e-140	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DEMHKHKO_02248	8.02e-152	plnU	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DEMHKHKO_02249	4.56e-144	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
DEMHKHKO_02250	3.74e-144	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DEMHKHKO_02251	4.23e-64	axe	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
DEMHKHKO_02252	0.0	-	-	-	L	-	-	-	DNA helicase
DEMHKHKO_02253	1.38e-179	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
DEMHKHKO_02254	2.35e-243	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
DEMHKHKO_02255	2.69e-166	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
DEMHKHKO_02256	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DEMHKHKO_02257	9.68e-34	-	-	-	-	-	-	-	-
DEMHKHKO_02258	1.69e-97	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
DEMHKHKO_02259	5.9e-46	-	-	-	-	-	-	-	-
DEMHKHKO_02260	1.6e-77	chpA	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
DEMHKHKO_02261	4.87e-243	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DEMHKHKO_02262	1.36e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
DEMHKHKO_02263	1.37e-290	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
DEMHKHKO_02264	7.71e-228	-	-	-	-	-	-	-	-
DEMHKHKO_02265	3.56e-170	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
DEMHKHKO_02266	1.12e-205	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
DEMHKHKO_02267	4.64e-92	-	-	-	F	-	-	-	DNA mismatch repair protein MutT
DEMHKHKO_02268	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DEMHKHKO_02269	1.81e-273	-	-	-	EGP	ko:K02030	-	ko00000,ko00002,ko02000	Drug resistance transporter Bcr CflA subfamily
DEMHKHKO_02270	2.53e-106	mutR	-	-	K	ko:K20373,ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
DEMHKHKO_02272	1.63e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
DEMHKHKO_02273	1.6e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DEMHKHKO_02274	1.19e-201	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
DEMHKHKO_02275	6.87e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
DEMHKHKO_02276	2.26e-209	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DEMHKHKO_02277	1.9e-230	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
DEMHKHKO_02278	8.05e-166	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
DEMHKHKO_02279	6.39e-169	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
DEMHKHKO_02280	2.2e-280	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
DEMHKHKO_02281	5.66e-74	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DEMHKHKO_02282	3.18e-77	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DEMHKHKO_02283	3.81e-18	-	-	-	-	-	-	-	-
DEMHKHKO_02284	1.29e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DEMHKHKO_02285	4.37e-208	fbpA	-	-	K	-	-	-	Domain of unknown function (DUF814)
DEMHKHKO_02286	1.15e-79	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
DEMHKHKO_02287	6.33e-46	-	-	-	-	-	-	-	-
DEMHKHKO_02288	3.38e-227	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
DEMHKHKO_02289	6.7e-148	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
DEMHKHKO_02290	1.24e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DEMHKHKO_02291	1.45e-278	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DEMHKHKO_02292	2.65e-102	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
DEMHKHKO_02293	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
DEMHKHKO_02294	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
DEMHKHKO_02295	1.03e-201	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
DEMHKHKO_02297	0.0	-	-	-	M	-	-	-	domain protein
DEMHKHKO_02298	5.44e-35	mleR	-	-	K	-	-	-	LysR substrate binding domain
DEMHKHKO_02299	1.63e-163	mleR	-	-	K	-	-	-	LysR substrate binding domain
DEMHKHKO_02300	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
DEMHKHKO_02301	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
DEMHKHKO_02302	4.71e-210	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
DEMHKHKO_02303	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
DEMHKHKO_02304	3.97e-229	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
DEMHKHKO_02305	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
DEMHKHKO_02306	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
DEMHKHKO_02307	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
DEMHKHKO_02308	6.27e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
DEMHKHKO_02309	1.17e-60	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
DEMHKHKO_02310	2.89e-312	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
DEMHKHKO_02311	3.66e-189	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
DEMHKHKO_02312	3.36e-216	-	-	-	K	-	-	-	LysR substrate binding domain
DEMHKHKO_02313	2.07e-302	-	-	-	EK	-	-	-	Aminotransferase, class I
DEMHKHKO_02314	2.13e-167	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
DEMHKHKO_02315	2.11e-158	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DEMHKHKO_02316	3.02e-176	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DEMHKHKO_02317	1.26e-161	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
DEMHKHKO_02318	1.07e-127	-	-	-	KT	-	-	-	response to antibiotic
DEMHKHKO_02319	2.86e-68	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
DEMHKHKO_02320	1.73e-132	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
DEMHKHKO_02321	1.6e-200	-	-	-	S	-	-	-	Putative adhesin
DEMHKHKO_02322	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
DEMHKHKO_02323	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
DEMHKHKO_02324	1.06e-232	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
DEMHKHKO_02325	3.73e-263	-	-	-	S	-	-	-	DUF218 domain
DEMHKHKO_02326	2.44e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
DEMHKHKO_02327	2.93e-151	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DEMHKHKO_02328	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DEMHKHKO_02329	6.26e-101	-	-	-	-	-	-	-	-
DEMHKHKO_02330	2.69e-194	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
DEMHKHKO_02331	3.54e-190	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
DEMHKHKO_02332	2.24e-116	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
DEMHKHKO_02333	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
DEMHKHKO_02334	9.49e-155	fptC	-	-	U	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase system, EIIC
DEMHKHKO_02335	2.52e-35	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DEMHKHKO_02336	5.55e-22	-	-	-	G	ko:K11203	-	ko00000,ko00002,ko02000	PTS system, fructose subfamily
DEMHKHKO_02337	1.5e-104	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DEMHKHKO_02338	1.15e-43	-	-	-	-	-	-	-	-
DEMHKHKO_02340	1.04e-269	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
DEMHKHKO_02341	4.54e-191	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
DEMHKHKO_02342	2.29e-193	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
DEMHKHKO_02343	5.21e-180	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
DEMHKHKO_02344	2.78e-158	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
DEMHKHKO_02345	3.13e-42	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
DEMHKHKO_02346	5.06e-82	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
DEMHKHKO_02347	1.27e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
DEMHKHKO_02348	5.52e-242	-	-	-	S	-	-	-	Cell surface protein
DEMHKHKO_02349	4.71e-81	-	-	-	-	-	-	-	-
DEMHKHKO_02350	0.0	-	-	-	-	-	-	-	-
DEMHKHKO_02351	6.97e-216	XK27_00670	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
DEMHKHKO_02352	5.82e-198	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
DEMHKHKO_02353	4.21e-150	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
DEMHKHKO_02354	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
DEMHKHKO_02355	8.08e-154	ydgI3	-	-	C	-	-	-	Nitroreductase family
DEMHKHKO_02356	2.21e-154	yceE	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
DEMHKHKO_02357	5.85e-204	ccpB	-	-	K	-	-	-	lacI family
DEMHKHKO_02358	7.39e-121	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
DEMHKHKO_02359	9.21e-234	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
DEMHKHKO_02360	1.02e-164	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
DEMHKHKO_02361	9.86e-117	-	-	-	-	-	-	-	-
DEMHKHKO_02362	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
DEMHKHKO_02363	3.06e-206	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
DEMHKHKO_02364	5.07e-62	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
DEMHKHKO_02365	5.93e-144	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
DEMHKHKO_02366	3.39e-225	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
DEMHKHKO_02367	6.12e-166	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
DEMHKHKO_02368	6.92e-206	yicL	-	-	EG	-	-	-	EamA-like transporter family
DEMHKHKO_02369	1.23e-26	-	-	-	-	-	-	-	-
DEMHKHKO_02370	2.46e-08	-	-	-	-	-	-	-	-
DEMHKHKO_02371	3.36e-06	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
DEMHKHKO_02372	1.88e-240	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
DEMHKHKO_02373	4.52e-209	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEMHKHKO_02374	2.03e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
DEMHKHKO_02375	2.53e-209	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
DEMHKHKO_02376	1.56e-185	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
DEMHKHKO_02377	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
DEMHKHKO_02378	3.33e-113	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
DEMHKHKO_02379	1.23e-129	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
DEMHKHKO_02380	5.88e-233	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
DEMHKHKO_02381	6.96e-83	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
DEMHKHKO_02382	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
DEMHKHKO_02383	5.03e-95	-	-	-	K	-	-	-	Transcriptional regulator
DEMHKHKO_02384	0.0	pox4	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
DEMHKHKO_02385	6.67e-165	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
DEMHKHKO_02386	8.76e-72	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
DEMHKHKO_02388	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
DEMHKHKO_02389	1.51e-85	-	-	-	KOT	ko:K07813	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01002	May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
DEMHKHKO_02390	9.62e-19	-	-	-	-	-	-	-	-
DEMHKHKO_02391	3.78e-212	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
DEMHKHKO_02392	7.42e-174	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
DEMHKHKO_02393	1.32e-101	nrp	-	-	K	ko:K16509	-	ko00000	ArsC family
DEMHKHKO_02394	0.0	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
DEMHKHKO_02395	1.96e-21	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
DEMHKHKO_02396	1.06e-16	-	-	-	-	-	-	-	-
DEMHKHKO_02397	2.1e-116	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
DEMHKHKO_02398	1.1e-147	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
DEMHKHKO_02399	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DEMHKHKO_02400	9.2e-317	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DEMHKHKO_02401	2.09e-85	-	-	-	-	-	-	-	-
DEMHKHKO_02402	2.85e-83	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
DEMHKHKO_02403	2.15e-281	-	-	-	S	-	-	-	Membrane
DEMHKHKO_02404	1.04e-59	-	-	-	S	-	-	-	Protein of unknown function (DUF3781)
DEMHKHKO_02405	1.31e-139	yoaZ	-	-	S	-	-	-	intracellular protease amidase
DEMHKHKO_02406	2.33e-56	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
DEMHKHKO_02407	5.36e-76	-	-	-	-	-	-	-	-
DEMHKHKO_02408	1.46e-81	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
DEMHKHKO_02409	5.31e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
DEMHKHKO_02410	3.17e-258	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
DEMHKHKO_02411	2e-62	-	-	-	K	-	-	-	Helix-turn-helix domain
DEMHKHKO_02412	3.87e-115	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
DEMHKHKO_02413	1.06e-72	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
DEMHKHKO_02414	5.53e-114	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DEMHKHKO_02415	6.79e-53	-	-	-	-	-	-	-	-
DEMHKHKO_02416	5.06e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DEMHKHKO_02417	1.6e-233	ydbI	-	-	K	-	-	-	AI-2E family transporter
DEMHKHKO_02418	9.28e-271	xylR	-	-	GK	-	-	-	ROK family
DEMHKHKO_02419	2.92e-143	-	-	-	-	-	-	-	-
DEMHKHKO_02420	3.66e-295	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
DEMHKHKO_02421	3.32e-210	-	-	-	-	-	-	-	-
DEMHKHKO_02422	1.86e-256	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
DEMHKHKO_02423	9.58e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
DEMHKHKO_02424	2.47e-125	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
DEMHKHKO_02425	9.69e-99	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
DEMHKHKO_02426	5.61e-39	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
DEMHKHKO_02427	1.74e-184	yxeH	-	-	S	-	-	-	hydrolase
DEMHKHKO_02428	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DEMHKHKO_02429	1.68e-146	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DEMHKHKO_02430	1.17e-305	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
DEMHKHKO_02431	7.29e-61	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system galactitol-specific IIB component
DEMHKHKO_02432	1.58e-101	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DEMHKHKO_02433	0.0	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DEMHKHKO_02434	9.14e-146	gph3	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
DEMHKHKO_02435	5.26e-247	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
DEMHKHKO_02436	8.37e-296	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
DEMHKHKO_02437	6e-60	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DEMHKHKO_02438	3.99e-106	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DEMHKHKO_02439	1.83e-146	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
DEMHKHKO_02440	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
DEMHKHKO_02441	3.76e-180	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
DEMHKHKO_02442	6.47e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
DEMHKHKO_02443	8.16e-48	-	-	-	I	-	-	-	alpha/beta hydrolase fold
DEMHKHKO_02444	3.21e-127	-	-	-	I	-	-	-	alpha/beta hydrolase fold
DEMHKHKO_02445	3.89e-205	-	-	-	I	-	-	-	alpha/beta hydrolase fold
DEMHKHKO_02446	0.0	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DEMHKHKO_02447	4.01e-263	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
DEMHKHKO_02448	9.03e-173	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
DEMHKHKO_02449	1.33e-196	nanK	-	-	GK	-	-	-	ROK family
DEMHKHKO_02450	1.86e-210	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
DEMHKHKO_02451	2.13e-159	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
DEMHKHKO_02452	5.6e-292	-	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
DEMHKHKO_02453	1.05e-225	hicD1	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
DEMHKHKO_02454	8.95e-60	-	-	-	-	-	-	-	-
DEMHKHKO_02455	1.99e-26	zmp1	-	-	O	-	-	-	Zinc-dependent metalloprotease
DEMHKHKO_02456	8.36e-154	rpiA2	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
DEMHKHKO_02457	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
DEMHKHKO_02458	5.34e-72	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
DEMHKHKO_02459	1.31e-124	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
DEMHKHKO_02460	1.54e-292	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
DEMHKHKO_02461	5.89e-108	-	-	-	K	-	-	-	Winged helix-turn-helix transcription repressor, HrcA DNA-binding
DEMHKHKO_02462	2.16e-103	-	-	-	-	-	-	-	-
DEMHKHKO_02463	2.32e-101	accB3	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
DEMHKHKO_02464	1.49e-223	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
DEMHKHKO_02465	2.42e-207	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
DEMHKHKO_02466	4.06e-102	-	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
DEMHKHKO_02467	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
DEMHKHKO_02468	2.7e-230	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
DEMHKHKO_02469	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
DEMHKHKO_02470	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DEMHKHKO_02471	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
DEMHKHKO_02472	2.14e-174	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
DEMHKHKO_02473	0.0	-	-	-	M	-	-	-	domain protein
DEMHKHKO_02474	6.75e-85	-	-	-	M	-	-	-	dTDP-4-dehydrorhamnose reductase activity
DEMHKHKO_02475	1.82e-34	-	-	-	S	-	-	-	Immunity protein 74
DEMHKHKO_02476	1.44e-20	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
DEMHKHKO_02478	3.54e-18	-	-	-	S	-	-	-	YopX protein
DEMHKHKO_02483	2.49e-97	-	-	-	K	-	-	-	acetyltransferase
DEMHKHKO_02484	1.15e-40	-	-	-	S	-	-	-	ASCH
DEMHKHKO_02485	7.56e-25	-	-	-	-	-	-	-	-
DEMHKHKO_02488	3.13e-98	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
DEMHKHKO_02490	2.91e-316	-	-	-	S	ko:K06909	-	ko00000	Phage terminase, large subunit
DEMHKHKO_02491	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
DEMHKHKO_02492	5.76e-216	-	-	-	S	-	-	-	Phage Mu protein F like protein
DEMHKHKO_02493	2.66e-110	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
DEMHKHKO_02494	2.45e-247	gpG	-	-	-	-	-	-	-
DEMHKHKO_02495	3.11e-75	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
DEMHKHKO_02496	5.46e-67	-	-	-	-	-	-	-	-
DEMHKHKO_02497	9.66e-123	-	-	-	-	-	-	-	-
DEMHKHKO_02498	5.59e-81	-	-	-	-	-	-	-	-
DEMHKHKO_02499	2.09e-123	-	-	-	-	-	-	-	-
DEMHKHKO_02500	5.37e-107	-	-	-	S	-	-	-	Phage tail assembly chaperone protein, TAC
DEMHKHKO_02502	0.0	-	-	-	D	-	-	-	domain protein
DEMHKHKO_02503	9.72e-173	-	-	-	S	-	-	-	phage tail
DEMHKHKO_02504	0.0	-	-	-	M	-	-	-	Prophage endopeptidase tail
DEMHKHKO_02505	2.64e-220	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
DEMHKHKO_02506	8.28e-127	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
DEMHKHKO_02510	1.4e-108	-	-	-	-	-	-	-	-
DEMHKHKO_02511	1.4e-27	-	-	-	-	-	-	-	-
DEMHKHKO_02513	2.91e-29	-	-	-	-	-	-	-	-
DEMHKHKO_02514	1.93e-102	-	-	-	-	-	-	-	-
DEMHKHKO_02518	0.0	-	-	-	S	-	-	-	Phage minor structural protein
DEMHKHKO_02519	0.0	-	-	-	S	-	-	-	Phage tail protein
DEMHKHKO_02520	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
DEMHKHKO_02521	3.35e-272	-	-	-	D	-	-	-	domain protein
DEMHKHKO_02522	6.36e-34	-	-	-	-	-	-	-	-
DEMHKHKO_02523	1.35e-75	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
DEMHKHKO_02524	2.16e-131	-	-	-	S	-	-	-	Phage tail tube protein
DEMHKHKO_02525	7.47e-74	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
DEMHKHKO_02526	2.25e-86	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
DEMHKHKO_02527	3.45e-76	-	-	-	S	-	-	-	Phage head-tail joining protein
DEMHKHKO_02528	9.36e-65	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
DEMHKHKO_02529	1.03e-254	-	-	-	S	-	-	-	Phage capsid family
DEMHKHKO_02530	5.99e-164	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
DEMHKHKO_02531	6.97e-284	-	-	-	S	-	-	-	Phage portal protein
DEMHKHKO_02532	6.68e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF1056)
DEMHKHKO_02533	0.0	-	-	-	S	-	-	-	Phage Terminase
DEMHKHKO_02534	6.68e-103	-	-	-	L	-	-	-	Phage terminase, small subunit
DEMHKHKO_02536	7.81e-113	-	-	-	L	-	-	-	HNH nucleases
DEMHKHKO_02537	1.26e-12	-	-	-	-	-	-	-	-
DEMHKHKO_02538	1.13e-84	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
DEMHKHKO_02539	2.2e-23	-	-	-	-	-	-	-	-
DEMHKHKO_02540	5.27e-72	-	-	-	-	-	-	-	-
DEMHKHKO_02541	1.28e-09	-	-	-	S	-	-	-	YopX protein
DEMHKHKO_02543	8.89e-118	-	-	-	L	-	-	-	C-5 cytosine-specific DNA methylase
DEMHKHKO_02545	2.95e-06	-	-	-	-	-	-	-	-
DEMHKHKO_02546	1.01e-20	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
DEMHKHKO_02547	1.89e-169	-	-	-	S	-	-	-	KR domain
DEMHKHKO_02548	2.56e-83	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
DEMHKHKO_02549	1.62e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF1905)
DEMHKHKO_02550	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
DEMHKHKO_02551	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
DEMHKHKO_02552	2.09e-213	-	-	-	GM	-	-	-	NmrA-like family
DEMHKHKO_02553	1.15e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DEMHKHKO_02554	5.93e-281	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
DEMHKHKO_02555	6.58e-173	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
DEMHKHKO_02556	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
DEMHKHKO_02557	7.81e-148	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
DEMHKHKO_02558	5.78e-269	-	-	-	EGP	-	-	-	Major Facilitator
DEMHKHKO_02559	3.25e-81	ytcD	-	-	K	-	-	-	Transcriptional regulator, HxlR family
DEMHKHKO_02560	1.06e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
DEMHKHKO_02561	4.13e-157	-	-	-	-	-	-	-	-
DEMHKHKO_02562	7.39e-300	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
DEMHKHKO_02563	1.47e-83	-	-	-	-	-	-	-	-
DEMHKHKO_02564	3.15e-130	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
DEMHKHKO_02565	2.16e-241	ynjC	-	-	S	-	-	-	Cell surface protein
DEMHKHKO_02566	2.63e-146	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
DEMHKHKO_02567	5.83e-87	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
DEMHKHKO_02568	6.57e-226	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
DEMHKHKO_02569	2.12e-77	-	-	-	M	-	-	-	Collagen binding domain
DEMHKHKO_02570	0.0	-	-	-	I	-	-	-	acetylesterase activity
DEMHKHKO_02571	2.35e-231	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
DEMHKHKO_02572	1.4e-20	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
DEMHKHKO_02573	1.4e-137	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
DEMHKHKO_02574	4.29e-50	-	-	-	-	-	-	-	-
DEMHKHKO_02576	1.37e-182	-	-	-	S	-	-	-	zinc-ribbon domain
DEMHKHKO_02577	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
DEMHKHKO_02578	0.0	-	4.1.1.98	-	H	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
DEMHKHKO_02579	4.34e-314	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
DEMHKHKO_02580	3.46e-210	-	-	-	K	-	-	-	LysR substrate binding domain
DEMHKHKO_02581	1.38e-131	-	-	-	-	-	-	-	-
DEMHKHKO_02582	3.7e-30	-	-	-	-	-	-	-	-
DEMHKHKO_02583	7.3e-245	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DEMHKHKO_02584	9.2e-243	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DEMHKHKO_02585	5.97e-96	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
DEMHKHKO_02586	1.56e-108	-	-	-	-	-	-	-	-
DEMHKHKO_02587	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
DEMHKHKO_02588	6.36e-134	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DEMHKHKO_02589	8.07e-163	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
DEMHKHKO_02590	2.56e-131	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
DEMHKHKO_02608	1.08e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
DEMHKHKO_02609	2.81e-178	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
DEMHKHKO_02610	9.28e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
DEMHKHKO_02611	7.12e-170	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
DEMHKHKO_02612	1.64e-17	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
DEMHKHKO_02613	1.52e-231	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
DEMHKHKO_02614	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
DEMHKHKO_02615	2.24e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
DEMHKHKO_02616	9.08e-157	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
DEMHKHKO_02617	1.29e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DEMHKHKO_02618	6.31e-222	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
DEMHKHKO_02619	7.21e-150	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
DEMHKHKO_02620	1.6e-246	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
DEMHKHKO_02621	2.68e-75	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
DEMHKHKO_02622	9.52e-264	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
DEMHKHKO_02623	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DEMHKHKO_02624	1.12e-207	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
DEMHKHKO_02626	3.59e-301	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
DEMHKHKO_02627	2.5e-147	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
DEMHKHKO_02628	4.97e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
DEMHKHKO_02629	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
DEMHKHKO_02630	7.81e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DEMHKHKO_02631	3.04e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DEMHKHKO_02632	1.79e-243	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
DEMHKHKO_02633	3.44e-204	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
DEMHKHKO_02634	1.88e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DEMHKHKO_02635	5e-141	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
DEMHKHKO_02636	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
DEMHKHKO_02637	3.04e-174	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
DEMHKHKO_02638	4.07e-249	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
DEMHKHKO_02639	3.76e-245	ampC	-	-	V	-	-	-	Beta-lactamase
DEMHKHKO_02640	8.57e-41	-	-	-	-	-	-	-	-
DEMHKHKO_02641	1.9e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
DEMHKHKO_02642	1.33e-77	-	-	-	-	-	-	-	-
DEMHKHKO_02643	1.08e-181	-	-	-	-	-	-	-	-
DEMHKHKO_02644	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
DEMHKHKO_02645	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
DEMHKHKO_02646	1.81e-85	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
DEMHKHKO_02647	2.91e-177	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
DEMHKHKO_02649	2.93e-73	-	-	-	V	-	-	-	Abortive infection bacteriophage resistance protein
DEMHKHKO_02650	5.11e-59	-	-	-	S	-	-	-	Bacteriophage holin
DEMHKHKO_02651	3.5e-307	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
DEMHKHKO_02652	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
DEMHKHKO_02653	4.63e-119	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
DEMHKHKO_02654	3.93e-59	-	-	-	-	-	-	-	-
DEMHKHKO_02655	9.42e-258	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
DEMHKHKO_02656	1.15e-198	tagG	-	-	U	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
DEMHKHKO_02657	1.57e-280	-	-	-	-	-	-	-	-
DEMHKHKO_02658	3.51e-281	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
DEMHKHKO_02659	3.08e-81	-	-	-	S	-	-	-	CHY zinc finger
DEMHKHKO_02660	6.8e-224	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
DEMHKHKO_02661	7.31e-122	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
DEMHKHKO_02662	6.4e-54	-	-	-	-	-	-	-	-
DEMHKHKO_02663	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
DEMHKHKO_02664	3.48e-40	-	-	-	-	-	-	-	-
DEMHKHKO_02665	5.81e-170	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
DEMHKHKO_02666	2.75e-304	xylP1	-	-	G	-	-	-	MFS/sugar transport protein
DEMHKHKO_02668	8.16e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
DEMHKHKO_02669	0.0	acdH	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
DEMHKHKO_02670	1.08e-243	-	-	-	-	-	-	-	-
DEMHKHKO_02671	1.85e-208	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DEMHKHKO_02672	5.05e-79	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
DEMHKHKO_02673	2.06e-30	-	-	-	-	-	-	-	-
DEMHKHKO_02674	2.14e-117	-	-	-	K	-	-	-	acetyltransferase
DEMHKHKO_02675	1.88e-111	-	-	-	K	-	-	-	GNAT family
DEMHKHKO_02676	8.08e-110	-	-	-	S	-	-	-	ASCH
DEMHKHKO_02677	3.68e-125	-	-	-	K	-	-	-	Cupin domain
DEMHKHKO_02678	8.8e-264	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
DEMHKHKO_02679	6.34e-190	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DEMHKHKO_02680	1.31e-179	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DEMHKHKO_02681	3.07e-264	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DEMHKHKO_02682	2.18e-53	-	-	-	-	-	-	-	-
DEMHKHKO_02683	9.59e-288	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
DEMHKHKO_02684	1.02e-98	-	-	-	K	-	-	-	Transcriptional regulator
DEMHKHKO_02685	9.81e-33	-	-	-	S	ko:K02348	-	ko00000	GNAT family
DEMHKHKO_02686	3.74e-284	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DEMHKHKO_02687	3.01e-75	-	-	-	-	-	-	-	-
DEMHKHKO_02688	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
DEMHKHKO_02689	3.27e-168	-	-	-	-	-	-	-	-
DEMHKHKO_02690	4.29e-227	-	-	-	-	-	-	-	-
DEMHKHKO_02691	4.2e-88	gcsH1	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Glycine cleavage H-protein
DEMHKHKO_02692	2.07e-40	-	-	-	-	-	-	-	-
DEMHKHKO_02693	7.92e-140	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
DEMHKHKO_02694	5.93e-73	-	-	-	S	-	-	-	branched-chain amino acid
DEMHKHKO_02695	2.05e-167	-	-	-	E	-	-	-	branched-chain amino acid
DEMHKHKO_02696	1.6e-114	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
DEMHKHKO_02697	3.1e-304	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
DEMHKHKO_02698	5.61e-273	hpk31	-	-	T	-	-	-	Histidine kinase
DEMHKHKO_02699	1.14e-159	vanR	-	-	K	-	-	-	response regulator
DEMHKHKO_02700	2.4e-161	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
DEMHKHKO_02701	3.3e-208	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
DEMHKHKO_02702	1.42e-269	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DEMHKHKO_02703	3.49e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
DEMHKHKO_02704	6.6e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
DEMHKHKO_02705	1.4e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
DEMHKHKO_02706	7.16e-201	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
DEMHKHKO_02707	1.01e-175	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
DEMHKHKO_02708	8.63e-191	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
DEMHKHKO_02709	1.81e-168	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
DEMHKHKO_02710	4.76e-288	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
DEMHKHKO_02711	2.87e-270	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
DEMHKHKO_02712	0.0	-	-	-	S	-	-	-	MucBP domain
DEMHKHKO_02713	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
DEMHKHKO_02714	4.33e-205	-	-	-	K	-	-	-	LysR substrate binding domain
DEMHKHKO_02715	1.85e-201	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
DEMHKHKO_02716	0.0	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
DEMHKHKO_02717	0.0	lepA2	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DEMHKHKO_02718	6.88e-152	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DEMHKHKO_02719	7.19e-89	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
DEMHKHKO_02720	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
DEMHKHKO_02721	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
DEMHKHKO_02722	2.44e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
DEMHKHKO_02723	0.0	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
DEMHKHKO_02724	2.91e-190	malA	-	-	S	-	-	-	maltodextrose utilization protein MalA
DEMHKHKO_02725	2.83e-206	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DEMHKHKO_02726	3.74e-302	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DEMHKHKO_02727	9.45e-299	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
DEMHKHKO_02729	2.84e-169	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
DEMHKHKO_02730	6.11e-56	-	-	-	L	-	-	-	DnaD domain protein
DEMHKHKO_02731	2.93e-167	-	-	-	S	-	-	-	Putative HNHc nuclease
DEMHKHKO_02732	3.13e-127	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
DEMHKHKO_02733	3.98e-151	-	-	-	S	-	-	-	AAA domain
DEMHKHKO_02734	4.24e-188	-	-	-	S	-	-	-	Protein of unknown function (DUF1351)
DEMHKHKO_02736	2e-25	-	-	-	-	-	-	-	-
DEMHKHKO_02743	7.34e-80	-	-	-	S	-	-	-	DNA binding
DEMHKHKO_02746	1.56e-27	-	-	-	-	-	-	-	-
DEMHKHKO_02747	2.59e-99	-	-	-	K	-	-	-	Peptidase S24-like
DEMHKHKO_02754	6.15e-75	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DEMHKHKO_02755	3.39e-52	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
DEMHKHKO_02756	1.71e-59	-	-	-	S	-	-	-	MORN repeat
DEMHKHKO_02757	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase family
DEMHKHKO_02758	1.81e-50	ydaS	-	-	S	-	-	-	Transglycosylase associated protein
DEMHKHKO_02759	1.37e-116	-	-	-	-	-	-	-	-
DEMHKHKO_02760	5.74e-32	-	-	-	-	-	-	-	-
DEMHKHKO_02761	1.1e-93	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
DEMHKHKO_02762	1.04e-94	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
DEMHKHKO_02763	2.02e-192	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
DEMHKHKO_02764	6.72e-208	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
DEMHKHKO_02765	5.6e-14	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
DEMHKHKO_02766	2.66e-132	-	-	-	G	-	-	-	Glycogen debranching enzyme
DEMHKHKO_02767	7.34e-155	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
DEMHKHKO_02768	3.26e-102	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
DEMHKHKO_02769	5.3e-157	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
DEMHKHKO_02770	4.29e-101	-	-	-	-	-	-	-	-
DEMHKHKO_02771	5.09e-51	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
DEMHKHKO_02772	2.42e-127	-	-	-	FG	-	-	-	HIT domain
DEMHKHKO_02773	4.27e-223	ydhF	-	-	S	-	-	-	Aldo keto reductase
DEMHKHKO_02774	5.17e-70	-	-	-	S	-	-	-	Pfam:DUF59
DEMHKHKO_02775	4.56e-206	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DEMHKHKO_02776	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
DEMHKHKO_02777	1.87e-249	-	-	-	V	-	-	-	Beta-lactamase
DEMHKHKO_02778	3.74e-125	-	-	-	V	-	-	-	VanZ like family
DEMHKHKO_02779	2.81e-181	-	-	-	K	-	-	-	Helix-turn-helix domain
DEMHKHKO_02780	2.97e-51	-	-	-	S	ko:K07343	-	ko00000	TfoX C-terminal domain
DEMHKHKO_02781	3.56e-288	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
DEMHKHKO_02782	0.0	-	-	-	-	-	-	-	-
DEMHKHKO_02783	3.15e-98	-	-	-	-	-	-	-	-
DEMHKHKO_02784	7.81e-241	-	-	-	S	-	-	-	Cell surface protein
DEMHKHKO_02785	6.02e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
DEMHKHKO_02786	4.31e-179	-	-	-	-	-	-	-	-
DEMHKHKO_02787	2.82e-236	-	-	-	S	-	-	-	DUF218 domain
DEMHKHKO_02788	3.26e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DEMHKHKO_02789	9.06e-193	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
DEMHKHKO_02790	5.78e-292	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DEMHKHKO_02791	1.96e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
DEMHKHKO_02792	5.3e-49	-	-	-	-	-	-	-	-
DEMHKHKO_02793	2.95e-57	-	-	-	S	-	-	-	ankyrin repeats
DEMHKHKO_02794	5.13e-119	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
DEMHKHKO_02795	7.59e-64	-	-	-	-	-	-	-	-
DEMHKHKO_02796	6.83e-274	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
DEMHKHKO_02797	8.05e-178	-	-	-	F	-	-	-	NUDIX domain
DEMHKHKO_02798	2.68e-32	-	-	-	-	-	-	-	-
DEMHKHKO_02800	8.51e-209	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
DEMHKHKO_02801	1.23e-222	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
DEMHKHKO_02802	3.43e-106	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
DEMHKHKO_02803	2.29e-48	-	-	-	-	-	-	-	-
DEMHKHKO_02804	4.54e-45	-	-	-	-	-	-	-	-
DEMHKHKO_02805	9.39e-277	-	-	-	T	-	-	-	diguanylate cyclase
DEMHKHKO_02806	2.51e-200	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
DEMHKHKO_02807	5.23e-277	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
DEMHKHKO_02808	0.0	yclK	-	-	T	-	-	-	Histidine kinase
DEMHKHKO_02809	1.45e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
DEMHKHKO_02810	2.12e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
DEMHKHKO_02811	1.06e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
DEMHKHKO_02812	2.55e-218	-	-	-	EG	-	-	-	EamA-like transporter family
DEMHKHKO_02814	2.08e-60	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
DEMHKHKO_02815	3.03e-49	-	-	-	K	-	-	-	sequence-specific DNA binding
DEMHKHKO_02816	9.13e-70	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
DEMHKHKO_02817	2.78e-231	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
DEMHKHKO_02818	1.98e-72	repA	-	-	S	-	-	-	Replication initiator protein A
DEMHKHKO_02819	1.32e-57	-	-	-	-	-	-	-	-
DEMHKHKO_02820	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
DEMHKHKO_02821	9.51e-142	XK27_07075	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
DEMHKHKO_02822	1.07e-74	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
DEMHKHKO_02823	2.13e-167	-	-	-	L	-	-	-	Helix-turn-helix domain
DEMHKHKO_02824	4.73e-206	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
DEMHKHKO_02825	6.16e-298	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
DEMHKHKO_02826	6.87e-204	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
DEMHKHKO_02827	9.73e-245	-	-	-	E	-	-	-	glutamine synthetase
DEMHKHKO_02828	5.63e-15	-	-	-	E	-	-	-	glutamine synthetase
DEMHKHKO_02829	2.06e-66	ykoF	-	-	S	-	-	-	YKOF-related Family
DEMHKHKO_02830	2.85e-57	-	-	-	-	-	-	-	-
DEMHKHKO_02831	7.39e-83	-	-	-	G	-	-	-	COG0662 Mannose-6-phosphate isomerase
DEMHKHKO_02832	1.81e-123	-	-	-	L	ko:K07498	-	ko00000	DDE domain
DEMHKHKO_02833	1.18e-194	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
DEMHKHKO_02835	9.4e-122	-	-	-	L	-	-	-	4.5 Transposon and IS
DEMHKHKO_02836	1.15e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase
DEMHKHKO_02838	1.19e-124	-	-	-	L	-	-	-	Resolvase, N terminal domain
DEMHKHKO_02839	7.8e-75	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
DEMHKHKO_02840	9.57e-315	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
DEMHKHKO_02841	3.35e-49	-	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
DEMHKHKO_02843	1.61e-74	mleR	-	-	K	-	-	-	LysR substrate binding domain
DEMHKHKO_02844	3.55e-169	-	-	-	K	-	-	-	LysR family
DEMHKHKO_02845	0.0	-	-	-	C	-	-	-	FMN_bind
DEMHKHKO_02846	2.17e-304	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
DEMHKHKO_02847	3.99e-101	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
DEMHKHKO_02848	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
DEMHKHKO_02851	3.71e-36	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
DEMHKHKO_02852	7.43e-130	padR	-	-	K	-	-	-	Virulence activator alpha C-term
DEMHKHKO_02853	2.51e-103	-	-	-	T	-	-	-	Universal stress protein family
DEMHKHKO_02854	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
DEMHKHKO_02856	1.87e-139	-	-	-	L	-	-	-	Integrase
DEMHKHKO_02857	4.17e-55	-	-	-	K	-	-	-	prlF antitoxin for toxin YhaV_toxin
DEMHKHKO_02858	1.03e-77	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
DEMHKHKO_02859	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
DEMHKHKO_02861	6.52e-52	-	-	-	S	-	-	-	protein conserved in bacteria
DEMHKHKO_02862	1.95e-25	-	-	-	-	-	-	-	-
DEMHKHKO_02863	3.1e-172	repA	-	-	S	-	-	-	Replication initiator protein A
DEMHKHKO_02864	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
DEMHKHKO_02865	6.22e-26	-	-	-	-	-	-	-	-
DEMHKHKO_02866	8.81e-48	-	-	-	L	-	-	-	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DEMHKHKO_02867	9.33e-249	-	-	-	U	ko:K07085	-	ko00000	Predicted Permease Membrane Region
DEMHKHKO_02868	5.32e-298	aspD	4.1.1.12	-	E	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	ko00000,ko00001,ko01000	Aminotransferase class I and II
DEMHKHKO_02869	1.48e-81	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DEMHKHKO_02870	1.89e-71	-	-	-	-	-	-	-	-
DEMHKHKO_02871	2.44e-303	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
DEMHKHKO_02872	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
DEMHKHKO_02873	8.86e-35	-	-	-	-	-	-	-	-
DEMHKHKO_02874	6.47e-10	-	-	-	P	-	-	-	Cation efflux family
DEMHKHKO_02875	7.86e-68	-	-	-	L	-	-	-	Transposase IS66 family
DEMHKHKO_02876	2.89e-256	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
DEMHKHKO_02877	3.9e-34	-	-	-	-	-	-	-	-
DEMHKHKO_02878	5.03e-75	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
DEMHKHKO_02879	4.16e-06	-	-	-	S	-	-	-	Transposase C of IS166 homeodomain
DEMHKHKO_02880	4.27e-146	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
DEMHKHKO_02881	3.23e-150	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
DEMHKHKO_02882	1.39e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DEMHKHKO_02883	4.31e-196	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
DEMHKHKO_02884	4.49e-74	-	-	-	L	-	-	-	Transposase DDE domain
DEMHKHKO_02885	3.72e-21	-	-	-	-	-	-	-	-
DEMHKHKO_02887	3.53e-38	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
DEMHKHKO_02888	1.92e-18	mpr	-	-	E	-	-	-	Trypsin-like serine protease
DEMHKHKO_02890	3.79e-26	-	-	-	-	-	-	-	-
DEMHKHKO_02891	2.64e-233	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
DEMHKHKO_02892	5.41e-89	-	-	-	C	-	-	-	lyase activity
DEMHKHKO_02893	6.34e-39	-	-	-	-	-	-	-	-
DEMHKHKO_02894	1.4e-13	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DEMHKHKO_02895	7.1e-81	-	-	-	S	-	-	-	Protein of unknown function (DUF2992)
DEMHKHKO_02896	7.57e-122	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DEMHKHKO_02897	3.47e-244	-	1.1.1.219	-	GM	ko:K00091	-	ko00000,ko01000	Male sterility protein
DEMHKHKO_02898	1.27e-129	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
DEMHKHKO_02899	1.16e-84	-	-	-	-	-	-	-	-
DEMHKHKO_02900	2.09e-151	-	-	-	-	-	-	-	-
DEMHKHKO_02901	5.15e-174	-	-	-	L	-	-	-	Replication protein
DEMHKHKO_02902	3.11e-17	-	-	-	S	-	-	-	protein with an alpha beta hydrolase fold
DEMHKHKO_02903	6.03e-36	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DEMHKHKO_02905	6.13e-127	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
DEMHKHKO_02906	1.18e-184	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
DEMHKHKO_02907	2.03e-31	-	-	-	S	-	-	-	Family of unknown function (DUF5388)
DEMHKHKO_02909	6.66e-115	-	-	-	-	-	-	-	-
DEMHKHKO_02910	2.29e-225	-	-	-	L	-	-	-	Initiator Replication protein
DEMHKHKO_02911	6.45e-111	-	-	-	-	-	-	-	-
DEMHKHKO_02912	2.83e-58	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
DEMHKHKO_02913	1.32e-107	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
DEMHKHKO_02914	2.26e-39	-	-	-	L	-	-	-	manually curated
DEMHKHKO_02915	4.05e-211	-	-	-	L	-	-	-	PFAM Integrase catalytic region
DEMHKHKO_02916	1.95e-114	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
DEMHKHKO_02917	3.62e-22	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
DEMHKHKO_02918	5.43e-167	-	-	-	S	-	-	-	Phage Mu protein F like protein
DEMHKHKO_02919	2.67e-75	-	-	-	-	-	-	-	-
DEMHKHKO_02920	2.54e-42	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
DEMHKHKO_02921	4.19e-54	-	-	-	-	-	-	-	-
DEMHKHKO_02922	9.51e-135	-	-	-	-	-	-	-	-
DEMHKHKO_02923	3.72e-14	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
DEMHKHKO_02924	8.04e-245	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
DEMHKHKO_02925	3.67e-41	-	-	-	-	-	-	-	-
DEMHKHKO_02926	3.12e-201	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
DEMHKHKO_02928	3.16e-59	-	-	-	T	ko:K07172	-	ko00000,ko02048	Antidote-toxin recognition MazE, bacterial antitoxin
DEMHKHKO_02929	3.2e-76	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
DEMHKHKO_02930	9.04e-78	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
DEMHKHKO_02931	1.11e-59	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
DEMHKHKO_02932	1.41e-163	-	-	-	P	-	-	-	integral membrane protein, YkoY family
DEMHKHKO_02934	3.47e-47	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
DEMHKHKO_02935	4.24e-178	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
DEMHKHKO_02937	2.43e-91	-	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
DEMHKHKO_02938	3.55e-76	-	-	-	-	-	-	-	-
DEMHKHKO_02939	6.01e-49	-	-	-	S	-	-	-	Bacteriophage holin
DEMHKHKO_02940	2.58e-147	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
DEMHKHKO_02942	1.39e-36	-	-	-	-	-	-	-	-
DEMHKHKO_02943	1.34e-34	-	-	-	-	-	-	-	-
DEMHKHKO_02944	7.92e-79	-	-	-	L	-	-	-	Integrase