Read a JSON File

ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HFFBLOFH_00001	7.17e-62	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HFFBLOFH_00002	2.15e-07	-	-	-	K	-	-	-	transcriptional regulator
HFFBLOFH_00003	5.58e-274	-	-	-	S	-	-	-	membrane
HFFBLOFH_00004	1.51e-105	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFFBLOFH_00005	0.0	-	-	-	S	-	-	-	Zinc finger, swim domain protein
HFFBLOFH_00006	8.09e-146	-	-	-	GM	-	-	-	epimerase
HFFBLOFH_00007	6.34e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
HFFBLOFH_00008	2.65e-93	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
HFFBLOFH_00009	1.4e-137	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HFFBLOFH_00010	1.68e-176	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HFFBLOFH_00011	0.0	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HFFBLOFH_00012	1.3e-264	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HFFBLOFH_00013	4.38e-102	-	-	-	K	-	-	-	Transcriptional regulator
HFFBLOFH_00014	4.6e-307	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
HFFBLOFH_00015	1.27e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HFFBLOFH_00016	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HFFBLOFH_00017	1.68e-229	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HFFBLOFH_00018	4.8e-278	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HFFBLOFH_00019	1.93e-266	-	-	-	-	-	-	-	-
HFFBLOFH_00020	6.11e-118	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HFFBLOFH_00021	2.65e-81	-	-	-	P	-	-	-	Rhodanese Homology Domain
HFFBLOFH_00022	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HFFBLOFH_00023	2.74e-112	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HFFBLOFH_00024	2.08e-213	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HFFBLOFH_00025	2.52e-165	drrB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HFFBLOFH_00026	1.75e-295	-	-	-	M	-	-	-	O-Antigen ligase
HFFBLOFH_00027	6.85e-164	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HFFBLOFH_00028	1.09e-249	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HFFBLOFH_00029	1.29e-298	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HFFBLOFH_00030	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HFFBLOFH_00032	7.03e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HFFBLOFH_00033	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HFFBLOFH_00034	8.69e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HFFBLOFH_00035	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HFFBLOFH_00036	2.51e-98	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
HFFBLOFH_00037	4.59e-217	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HFFBLOFH_00038	3.13e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HFFBLOFH_00039	3.99e-92	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HFFBLOFH_00040	7.1e-176	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HFFBLOFH_00041	1.3e-132	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HFFBLOFH_00042	2.69e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HFFBLOFH_00043	2.24e-126	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HFFBLOFH_00044	3.38e-252	-	-	-	S	-	-	-	Helix-turn-helix domain
HFFBLOFH_00045	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HFFBLOFH_00046	1.25e-39	-	-	-	M	-	-	-	Lysin motif
HFFBLOFH_00047	1.27e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HFFBLOFH_00048	1.98e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HFFBLOFH_00049	5.89e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HFFBLOFH_00050	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HFFBLOFH_00051	2.08e-284	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HFFBLOFH_00052	1.29e-192	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HFFBLOFH_00053	1.39e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HFFBLOFH_00054	6.04e-290	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HFFBLOFH_00055	6.46e-109	-	-	-	-	-	-	-	-
HFFBLOFH_00056	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HFFBLOFH_00057	6.7e-241	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HFFBLOFH_00058	1.8e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HFFBLOFH_00059	2.03e-189	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HFFBLOFH_00060	1.19e-208	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HFFBLOFH_00061	3.29e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HFFBLOFH_00062	9.33e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HFFBLOFH_00063	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HFFBLOFH_00064	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HFFBLOFH_00065	4.28e-253	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HFFBLOFH_00066	3.53e-160	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HFFBLOFH_00067	1.27e-222	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
HFFBLOFH_00068	1.73e-219	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
HFFBLOFH_00069	5.99e-291	XK27_05470	-	-	E	-	-	-	Methionine synthase
HFFBLOFH_00071	2.25e-207	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HFFBLOFH_00072	8.64e-177	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFFBLOFH_00073	2.33e-202	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HFFBLOFH_00074	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HFFBLOFH_00075	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HFFBLOFH_00076	1.5e-227	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HFFBLOFH_00077	6.84e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HFFBLOFH_00078	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HFFBLOFH_00079	3.64e-217	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HFFBLOFH_00080	2.4e-137	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HFFBLOFH_00081	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HFFBLOFH_00082	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HFFBLOFH_00083	2.21e-227	-	-	-	K	-	-	-	Transcriptional regulator
HFFBLOFH_00084	3.21e-215	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HFFBLOFH_00085	3.8e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HFFBLOFH_00086	9.17e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HFFBLOFH_00087	1.07e-43	-	-	-	S	-	-	-	YozE SAM-like fold
HFFBLOFH_00088	3.59e-204	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HFFBLOFH_00089	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HFFBLOFH_00090	4.49e-315	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HFFBLOFH_00091	3.22e-87	-	-	-	-	-	-	-	-
HFFBLOFH_00092	0.0	gshR1	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HFFBLOFH_00093	1.48e-98	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HFFBLOFH_00094	4.87e-123	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HFFBLOFH_00095	0.0	tarL	2.7.8.14, 2.7.8.47	-	H	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HFFBLOFH_00096	1.43e-273	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	H	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HFFBLOFH_00097	6.51e-247	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HFFBLOFH_00098	2.13e-151	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HFFBLOFH_00099	4.76e-290	-	-	-	-	-	-	-	-
HFFBLOFH_00100	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HFFBLOFH_00101	7.79e-78	-	-	-	-	-	-	-	-
HFFBLOFH_00102	2.79e-181	-	-	-	-	-	-	-	-
HFFBLOFH_00103	1.06e-312	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HFFBLOFH_00104	1.05e-176	XK27_00890	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
HFFBLOFH_00105	9.3e-167	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
HFFBLOFH_00106	1.33e-67	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
HFFBLOFH_00108	6e-268	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
HFFBLOFH_00109	4.87e-191	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HFFBLOFH_00110	2.37e-65	-	-	-	-	-	-	-	-
HFFBLOFH_00111	1.27e-35	-	-	-	-	-	-	-	-
HFFBLOFH_00112	1.96e-168	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HFFBLOFH_00113	2.47e-101	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
HFFBLOFH_00114	4.53e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
HFFBLOFH_00115	1.97e-87	-	-	-	K	-	-	-	Transcriptional regulator
HFFBLOFH_00116	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HFFBLOFH_00117	1.6e-171	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HFFBLOFH_00118	2.16e-208	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFFBLOFH_00119	1.37e-119	-	-	-	F	-	-	-	NUDIX domain
HFFBLOFH_00120	1.19e-176	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
HFFBLOFH_00121	2.08e-92	-	-	-	S	-	-	-	LuxR family transcriptional regulator
HFFBLOFH_00122	1.92e-168	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
HFFBLOFH_00125	1.9e-93	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HFFBLOFH_00126	3.34e-144	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HFFBLOFH_00127	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HFFBLOFH_00128	4.89e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HFFBLOFH_00129	1.9e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HFFBLOFH_00130	9.72e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HFFBLOFH_00131	1.65e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HFFBLOFH_00132	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HFFBLOFH_00133	5.89e-81	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HFFBLOFH_00134	3.28e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HFFBLOFH_00135	2.44e-267	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
HFFBLOFH_00136	2.13e-186	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
HFFBLOFH_00137	2.27e-247	-	-	-	-	-	-	-	-
HFFBLOFH_00138	1.9e-156	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HFFBLOFH_00139	4.35e-159	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HFFBLOFH_00140	1.38e-232	-	-	-	V	-	-	-	LD-carboxypeptidase
HFFBLOFH_00141	1.23e-311	-	-	-	M	ko:K07273	-	ko00000	hydrolase, family 25
HFFBLOFH_00142	3.2e-70	-	-	-	-	-	-	-	-
HFFBLOFH_00143	3.15e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HFFBLOFH_00144	1.57e-179	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HFFBLOFH_00145	6.42e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HFFBLOFH_00146	9.99e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HFFBLOFH_00147	1.6e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HFFBLOFH_00148	7.69e-300	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HFFBLOFH_00149	1.46e-77	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HFFBLOFH_00150	2.85e-293	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HFFBLOFH_00151	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HFFBLOFH_00152	4.49e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HFFBLOFH_00153	3.33e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HFFBLOFH_00154	2.17e-244	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HFFBLOFH_00155	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HFFBLOFH_00156	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HFFBLOFH_00157	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HFFBLOFH_00158	1.61e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HFFBLOFH_00159	1.84e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HFFBLOFH_00160	3.16e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HFFBLOFH_00161	1.21e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HFFBLOFH_00162	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HFFBLOFH_00163	1.62e-173	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HFFBLOFH_00164	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HFFBLOFH_00165	1.01e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HFFBLOFH_00166	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HFFBLOFH_00167	1.02e-277	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HFFBLOFH_00168	3.93e-41	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HFFBLOFH_00169	6.96e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HFFBLOFH_00170	8.28e-73	-	-	-	-	-	-	-	-
HFFBLOFH_00171	1.36e-136	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HFFBLOFH_00172	3.8e-224	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HFFBLOFH_00173	7.11e-135	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFFBLOFH_00174	4.51e-284	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HFFBLOFH_00175	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HFFBLOFH_00176	2.15e-99	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HFFBLOFH_00177	4.49e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HFFBLOFH_00178	7.16e-201	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HFFBLOFH_00179	7.55e-44	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFFBLOFH_00180	3.28e-312	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFFBLOFH_00181	4.82e-194	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HFFBLOFH_00182	2.82e-91	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HFFBLOFH_00183	1.7e-96	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HFFBLOFH_00184	1.43e-129	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HFFBLOFH_00185	4.08e-247	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HFFBLOFH_00186	2.33e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HFFBLOFH_00187	7.97e-71	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HFFBLOFH_00188	1.55e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HFFBLOFH_00189	8.15e-125	-	-	-	K	-	-	-	Transcriptional regulator
HFFBLOFH_00190	9.81e-27	-	-	-	-	-	-	-	-
HFFBLOFH_00193	2.97e-41	-	-	-	-	-	-	-	-
HFFBLOFH_00194	3.11e-73	-	-	-	-	-	-	-	-
HFFBLOFH_00195	2.92e-126	-	-	-	S	-	-	-	Protein conserved in bacteria
HFFBLOFH_00196	1.34e-232	-	-	-	-	-	-	-	-
HFFBLOFH_00197	1.18e-205	-	-	-	-	-	-	-	-
HFFBLOFH_00198	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HFFBLOFH_00199	7.79e-85	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
HFFBLOFH_00200	3.8e-224	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HFFBLOFH_00201	7.77e-179	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HFFBLOFH_00202	1.44e-31	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HFFBLOFH_00203	1.15e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HFFBLOFH_00204	1.62e-141	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HFFBLOFH_00205	2.6e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HFFBLOFH_00206	6.33e-46	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HFFBLOFH_00207	3.52e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HFFBLOFH_00208	9.29e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HFFBLOFH_00209	5.33e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HFFBLOFH_00210	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HFFBLOFH_00211	0.0	-	-	-	S	-	-	-	membrane
HFFBLOFH_00212	6.12e-72	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HFFBLOFH_00213	5.72e-99	-	-	-	K	-	-	-	LytTr DNA-binding domain
HFFBLOFH_00214	9.72e-146	-	-	-	S	-	-	-	membrane
HFFBLOFH_00215	1.09e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HFFBLOFH_00216	7.5e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HFFBLOFH_00217	6.11e-249	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HFFBLOFH_00218	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HFFBLOFH_00219	6.88e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HFFBLOFH_00220	2.58e-82	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HFFBLOFH_00221	1.72e-120	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HFFBLOFH_00222	4.46e-179	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFFBLOFH_00223	1.37e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HFFBLOFH_00224	6.94e-209	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HFFBLOFH_00225	4.18e-121	-	-	-	S	-	-	-	SdpI/YhfL protein family
HFFBLOFH_00226	1.36e-288	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HFFBLOFH_00227	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HFFBLOFH_00228	1.93e-218	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HFFBLOFH_00229	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFFBLOFH_00230	1.38e-155	csrR	-	-	K	-	-	-	response regulator
HFFBLOFH_00231	2.56e-310	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HFFBLOFH_00232	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HFFBLOFH_00233	1.09e-223	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HFFBLOFH_00234	3.06e-124	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HFFBLOFH_00235	3.66e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HFFBLOFH_00236	3.04e-280	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HFFBLOFH_00237	3.3e-180	yqeM	-	-	Q	-	-	-	Methyltransferase
HFFBLOFH_00238	1.06e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HFFBLOFH_00239	1.71e-149	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HFFBLOFH_00240	4.19e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HFFBLOFH_00241	2.19e-67	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HFFBLOFH_00242	3.81e-276	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HFFBLOFH_00243	5.7e-127	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HFFBLOFH_00244	6.32e-114	-	-	-	-	-	-	-	-
HFFBLOFH_00245	1.7e-281	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HFFBLOFH_00246	3.97e-174	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HFFBLOFH_00247	1.64e-83	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HFFBLOFH_00248	1.18e-250	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HFFBLOFH_00249	7.03e-307	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
HFFBLOFH_00250	4.59e-73	-	-	-	-	-	-	-	-
HFFBLOFH_00251	6.88e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HFFBLOFH_00252	6.92e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HFFBLOFH_00253	2.37e-109	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HFFBLOFH_00254	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HFFBLOFH_00255	3.5e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HFFBLOFH_00256	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HFFBLOFH_00257	1.58e-117	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HFFBLOFH_00258	1.92e-133	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HFFBLOFH_00259	3.19e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HFFBLOFH_00260	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HFFBLOFH_00261	8.51e-155	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HFFBLOFH_00262	1.04e-141	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HFFBLOFH_00263	4.07e-60	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HFFBLOFH_00264	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HFFBLOFH_00265	2.71e-108	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HFFBLOFH_00266	1.11e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HFFBLOFH_00267	5.21e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HFFBLOFH_00268	1.1e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HFFBLOFH_00269	2.87e-47	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
HFFBLOFH_00270	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HFFBLOFH_00271	3.04e-29	-	-	-	S	-	-	-	Virus attachment protein p12 family
HFFBLOFH_00272	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HFFBLOFH_00273	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HFFBLOFH_00274	1.29e-148	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HFFBLOFH_00275	2.94e-71	ytzB	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HFFBLOFH_00276	2.8e-155	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HFFBLOFH_00277	7.24e-197	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
HFFBLOFH_00278	8.17e-285	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HFFBLOFH_00279	1.1e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFFBLOFH_00280	3.6e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HFFBLOFH_00281	6.76e-73	-	-	-	-	-	-	-	-
HFFBLOFH_00282	1.09e-196	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HFFBLOFH_00283	1.78e-153	draG	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HFFBLOFH_00284	5.76e-135	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HFFBLOFH_00285	2.82e-138	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HFFBLOFH_00286	1.94e-247	-	-	-	S	-	-	-	Fn3-like domain
HFFBLOFH_00287	1.65e-80	-	-	-	-	-	-	-	-
HFFBLOFH_00288	0.0	-	-	-	-	-	-	-	-
HFFBLOFH_00289	4.26e-308	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HFFBLOFH_00290	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HFFBLOFH_00291	1.83e-37	-	-	-	-	-	-	-	-
HFFBLOFH_00292	1.19e-186	-	-	-	S	ko:K06889	-	ko00000	Dienelactone hydrolase family
HFFBLOFH_00293	9.89e-74	ytpP	-	-	CO	-	-	-	Thioredoxin
HFFBLOFH_00294	3.87e-262	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HFFBLOFH_00295	3.89e-62	-	-	-	-	-	-	-	-
HFFBLOFH_00296	2.57e-70	-	-	-	-	-	-	-	-
HFFBLOFH_00297	6.94e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2798)
HFFBLOFH_00298	1.65e-97	-	-	-	-	-	-	-	-
HFFBLOFH_00299	4.15e-78	-	-	-	-	-	-	-	-
HFFBLOFH_00300	4.26e-250	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HFFBLOFH_00301	0.0	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
HFFBLOFH_00302	2.51e-103	uspA3	-	-	T	-	-	-	universal stress protein
HFFBLOFH_00303	2.5e-203	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HFFBLOFH_00304	4.05e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HFFBLOFH_00305	1.38e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HFFBLOFH_00306	1.25e-283	-	-	-	M	-	-	-	Glycosyl transferases group 1
HFFBLOFH_00307	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HFFBLOFH_00308	2.01e-209	-	-	-	S	-	-	-	Putative esterase
HFFBLOFH_00309	3.53e-169	-	-	-	K	-	-	-	Transcriptional regulator
HFFBLOFH_00310	4.75e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HFFBLOFH_00311	2.48e-178	-	-	-	-	-	-	-	-
HFFBLOFH_00312	1.97e-150	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HFFBLOFH_00313	8.05e-179	rrp8	-	-	K	-	-	-	LytTr DNA-binding domain
HFFBLOFH_00314	1.7e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HFFBLOFH_00315	1.55e-79	-	-	-	-	-	-	-	-
HFFBLOFH_00316	2.61e-96	hsp2	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HFFBLOFH_00317	2.97e-76	-	-	-	-	-	-	-	-
HFFBLOFH_00318	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HFFBLOFH_00319	1.18e-114	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HFFBLOFH_00320	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HFFBLOFH_00321	2.03e-271	yttB	-	-	EGP	-	-	-	Major Facilitator
HFFBLOFH_00322	3.45e-83	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HFFBLOFH_00323	9.75e-39	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HFFBLOFH_00324	4.68e-161	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HFFBLOFH_00325	4.71e-74	-	-	-	S	-	-	-	SdpI/YhfL protein family
HFFBLOFH_00326	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HFFBLOFH_00327	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	Bacterial regulatory proteins, gntR family
HFFBLOFH_00328	1.02e-277	araT2	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HFFBLOFH_00329	1.84e-204	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HFFBLOFH_00330	3.59e-26	-	-	-	-	-	-	-	-
HFFBLOFH_00331	2.09e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HFFBLOFH_00332	6.68e-207	mleR	-	-	K	-	-	-	LysR family
HFFBLOFH_00333	1.29e-148	-	-	-	GM	-	-	-	NAD(P)H-binding
HFFBLOFH_00334	3.86e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HFFBLOFH_00335	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HFFBLOFH_00336	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HFFBLOFH_00337	1.12e-216	oroP	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
HFFBLOFH_00338	5.46e-145	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HFFBLOFH_00339	1.55e-161	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HFFBLOFH_00340	1.04e-218	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HFFBLOFH_00341	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HFFBLOFH_00342	2.76e-271	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HFFBLOFH_00343	1.61e-308	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HFFBLOFH_00344	2.02e-219	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HFFBLOFH_00345	7.13e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HFFBLOFH_00346	0.0	pucR_2	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
HFFBLOFH_00347	3.1e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HFFBLOFH_00348	5.67e-280	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
HFFBLOFH_00349	2.24e-206	-	-	-	GM	-	-	-	NmrA-like family
HFFBLOFH_00350	1.25e-199	-	-	-	T	-	-	-	EAL domain
HFFBLOFH_00351	1.85e-121	-	-	-	-	-	-	-	-
HFFBLOFH_00352	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HFFBLOFH_00353	1.83e-157	-	-	-	E	-	-	-	Methionine synthase
HFFBLOFH_00354	9.06e-279	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HFFBLOFH_00355	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HFFBLOFH_00356	5.35e-133	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HFFBLOFH_00357	4.22e-243	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HFFBLOFH_00358	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HFFBLOFH_00359	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFFBLOFH_00360	6.91e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFFBLOFH_00361	1.17e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFFBLOFH_00362	3.39e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HFFBLOFH_00363	2.87e-270	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HFFBLOFH_00364	3.77e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HFFBLOFH_00365	4.57e-304	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HFFBLOFH_00366	9.92e-143	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HFFBLOFH_00367	5.76e-243	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
HFFBLOFH_00368	4.81e-188	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HFFBLOFH_00369	5.95e-153	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
HFFBLOFH_00370	6.89e-190	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HFFBLOFH_00371	3.7e-233	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HFFBLOFH_00372	2.05e-178	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFFBLOFH_00373	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HFFBLOFH_00374	1.87e-53	-	-	-	-	-	-	-	-
HFFBLOFH_00375	8.2e-81	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HFFBLOFH_00376	7.89e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFFBLOFH_00377	4.21e-175	-	-	-	-	-	-	-	-
HFFBLOFH_00378	1.1e-103	usp5	-	-	T	-	-	-	universal stress protein
HFFBLOFH_00379	3.64e-46	-	-	-	-	-	-	-	-
HFFBLOFH_00380	5.7e-95	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HFFBLOFH_00381	1.76e-114	-	-	-	-	-	-	-	-
HFFBLOFH_00382	5.92e-67	-	-	-	-	-	-	-	-
HFFBLOFH_00383	4.79e-13	-	-	-	-	-	-	-	-
HFFBLOFH_00384	3.03e-299	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HFFBLOFH_00385	1.16e-110	-	-	-	F	-	-	-	belongs to the nudix hydrolase family
HFFBLOFH_00386	1.52e-151	-	-	-	-	-	-	-	-
HFFBLOFH_00387	1.21e-69	-	-	-	-	-	-	-	-
HFFBLOFH_00389	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HFFBLOFH_00390	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HFFBLOFH_00391	4.65e-186	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HFFBLOFH_00392	2.99e-38	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
HFFBLOFH_00393	5.88e-142	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HFFBLOFH_00394	1.13e-132	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HFFBLOFH_00395	2.26e-91	-	-	-	FG	-	-	-	Scavenger mRNA decapping enzyme C-term binding
HFFBLOFH_00396	5.41e-172	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HFFBLOFH_00397	3.25e-48	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
HFFBLOFH_00398	2.45e-269	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HFFBLOFH_00399	4.43e-294	-	-	-	S	-	-	-	Sterol carrier protein domain
HFFBLOFH_00400	7.54e-115	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
HFFBLOFH_00401	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HFFBLOFH_00402	6.09e-152	-	-	-	K	-	-	-	Transcriptional regulator
HFFBLOFH_00403	9.24e-231	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HFFBLOFH_00404	4.29e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HFFBLOFH_00405	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HFFBLOFH_00406	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFFBLOFH_00407	0.0	pbg5	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFFBLOFH_00408	6.7e-74	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
HFFBLOFH_00409	1.86e-64	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HFFBLOFH_00410	1.23e-166	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HFFBLOFH_00411	1.4e-181	epsV	-	-	S	-	-	-	glycosyl transferase family 2
HFFBLOFH_00412	1.75e-156	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
HFFBLOFH_00413	7.63e-107	-	-	-	-	-	-	-	-
HFFBLOFH_00414	5.06e-196	-	-	-	S	-	-	-	hydrolase
HFFBLOFH_00415	6.86e-232	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HFFBLOFH_00416	3.98e-204	-	-	-	EG	-	-	-	EamA-like transporter family
HFFBLOFH_00417	1.96e-224	serA1	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HFFBLOFH_00418	1.54e-131	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HFFBLOFH_00419	0.0	-	-	-	-	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	-
HFFBLOFH_00420	4.75e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HFFBLOFH_00421	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HFFBLOFH_00422	9.78e-187	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HFFBLOFH_00423	0.0	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HFFBLOFH_00424	4.3e-44	-	-	-	-	-	-	-	-
HFFBLOFH_00425	2.38e-164	aroC1	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
HFFBLOFH_00426	0.0	ycaM	-	-	E	-	-	-	amino acid
HFFBLOFH_00427	5.73e-100	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HFFBLOFH_00428	1.66e-211	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
HFFBLOFH_00429	2.43e-206	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HFFBLOFH_00430	2.16e-208	-	-	-	K	-	-	-	Transcriptional regulator
HFFBLOFH_00432	2e-98	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	general stress protein
HFFBLOFH_00433	5.16e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HFFBLOFH_00434	8.38e-152	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HFFBLOFH_00435	2.71e-150	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HFFBLOFH_00436	7.18e-189	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HFFBLOFH_00437	1.96e-116	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HFFBLOFH_00438	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HFFBLOFH_00439	5.77e-151	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HFFBLOFH_00440	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HFFBLOFH_00441	4.7e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFFBLOFH_00442	3.68e-235	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HFFBLOFH_00444	6.46e-113	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
HFFBLOFH_00445	3.03e-27	-	-	-	-	ko:K02671	-	ko00000,ko02035,ko02044	-
HFFBLOFH_00446	1.5e-108	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
HFFBLOFH_00447	1.97e-72	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HFFBLOFH_00448	6.2e-242	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HFFBLOFH_00449	2.57e-224	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HFFBLOFH_00450	2.06e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HFFBLOFH_00451	2.21e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HFFBLOFH_00452	2.44e-65	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
HFFBLOFH_00453	3.21e-210	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HFFBLOFH_00454	5.44e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HFFBLOFH_00455	7.36e-274	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HFFBLOFH_00456	9.86e-82	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HFFBLOFH_00457	1.6e-96	-	-	-	-	-	-	-	-
HFFBLOFH_00458	1.88e-75	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HFFBLOFH_00459	2.31e-202	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HFFBLOFH_00460	6.72e-289	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HFFBLOFH_00461	2.29e-112	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HFFBLOFH_00462	7.94e-114	ykuL	-	-	S	-	-	-	(CBS) domain
HFFBLOFH_00463	4.03e-125	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HFFBLOFH_00464	8.49e-144	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HFFBLOFH_00465	5.06e-194	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HFFBLOFH_00466	1.45e-161	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HFFBLOFH_00467	3e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HFFBLOFH_00468	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HFFBLOFH_00469	1.06e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HFFBLOFH_00470	1.31e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HFFBLOFH_00471	5.39e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HFFBLOFH_00472	5e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HFFBLOFH_00473	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HFFBLOFH_00474	2.79e-316	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HFFBLOFH_00475	8.32e-227	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HFFBLOFH_00476	2.48e-276	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HFFBLOFH_00477	1.32e-63	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HFFBLOFH_00478	9.91e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HFFBLOFH_00479	5.87e-256	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HFFBLOFH_00480	2.62e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HFFBLOFH_00481	2.83e-138	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HFFBLOFH_00482	4.02e-114	-	-	-	-	-	-	-	-
HFFBLOFH_00483	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HFFBLOFH_00484	1.3e-91	-	-	-	-	-	-	-	-
HFFBLOFH_00485	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
HFFBLOFH_00486	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HFFBLOFH_00487	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HFFBLOFH_00488	6.18e-197	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
HFFBLOFH_00489	6.57e-291	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HFFBLOFH_00490	2.43e-264	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HFFBLOFH_00491	3.83e-295	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HFFBLOFH_00492	1.92e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HFFBLOFH_00493	5.74e-172	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HFFBLOFH_00494	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
HFFBLOFH_00495	3.55e-296	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HFFBLOFH_00496	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HFFBLOFH_00497	2.61e-199	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HFFBLOFH_00498	3.17e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFFBLOFH_00499	1.89e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HFFBLOFH_00500	1.23e-187	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HFFBLOFH_00501	3.81e-150	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HFFBLOFH_00502	9.47e-115	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HFFBLOFH_00503	3.76e-184	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HFFBLOFH_00504	1.74e-211	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HFFBLOFH_00505	1.15e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HFFBLOFH_00506	5.62e-316	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HFFBLOFH_00507	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HFFBLOFH_00508	3.56e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HFFBLOFH_00509	1.57e-299	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
HFFBLOFH_00510	8.93e-291	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HFFBLOFH_00511	2.59e-277	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HFFBLOFH_00512	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HFFBLOFH_00513	7.5e-105	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HFFBLOFH_00514	2.15e-137	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HFFBLOFH_00515	4.02e-145	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HFFBLOFH_00516	1.63e-104	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HFFBLOFH_00517	1.24e-139	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HFFBLOFH_00518	9.17e-59	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HFFBLOFH_00519	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HFFBLOFH_00520	7.27e-303	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HFFBLOFH_00521	1.34e-52	-	-	-	-	-	-	-	-
HFFBLOFH_00522	2.37e-107	uspA	-	-	T	-	-	-	universal stress protein
HFFBLOFH_00523	1.1e-258	bla2	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HFFBLOFH_00524	4.7e-207	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HFFBLOFH_00525	0.0	glpQ3	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HFFBLOFH_00526	6.54e-273	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HFFBLOFH_00527	7.55e-242	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HFFBLOFH_00528	3.26e-227	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HFFBLOFH_00529	3.34e-215	hicD3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HFFBLOFH_00530	8.69e-191	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HFFBLOFH_00531	2.1e-151	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFFBLOFH_00532	2.24e-239	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HFFBLOFH_00533	3.2e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
HFFBLOFH_00534	2.15e-280	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HFFBLOFH_00535	1.04e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HFFBLOFH_00536	1.52e-57	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HFFBLOFH_00537	1.44e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HFFBLOFH_00538	1.68e-132	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HFFBLOFH_00539	4.85e-314	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HFFBLOFH_00540	5.95e-74	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HFFBLOFH_00541	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HFFBLOFH_00542	9.14e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HFFBLOFH_00543	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HFFBLOFH_00544	2.03e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFFBLOFH_00545	5.41e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HFFBLOFH_00546	1.81e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFFBLOFH_00547	4.82e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HFFBLOFH_00548	1.01e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HFFBLOFH_00549	7.21e-145	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
HFFBLOFH_00550	2.31e-132	thgA3	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HFFBLOFH_00551	2.49e-167	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HFFBLOFH_00552	8.81e-205	-	-	-	S	-	-	-	Alpha beta hydrolase
HFFBLOFH_00553	1.39e-143	-	-	-	GM	-	-	-	NmrA-like family
HFFBLOFH_00554	1.74e-101	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
HFFBLOFH_00555	5.72e-207	-	-	-	K	-	-	-	Transcriptional regulator
HFFBLOFH_00556	3.78e-221	cryZ	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HFFBLOFH_00558	0.0	nox4	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HFFBLOFH_00559	1.51e-132	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
HFFBLOFH_00560	5.11e-266	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFFBLOFH_00561	1.27e-174	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HFFBLOFH_00562	4.17e-204	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HFFBLOFH_00564	6.64e-109	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HFFBLOFH_00565	2.25e-93	-	-	-	K	-	-	-	MarR family
HFFBLOFH_00566	1.49e-147	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HFFBLOFH_00567	0.000138	yjdF	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HFFBLOFH_00568	1.03e-206	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFFBLOFH_00569	6.05e-170	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HFFBLOFH_00570	1.43e-251	-	-	-	-	-	-	-	-
HFFBLOFH_00571	5.23e-256	-	-	-	-	-	-	-	-
HFFBLOFH_00572	4.94e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFFBLOFH_00573	1.18e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HFFBLOFH_00574	1.74e-251	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HFFBLOFH_00575	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HFFBLOFH_00576	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HFFBLOFH_00577	8.64e-224	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HFFBLOFH_00578	2.84e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HFFBLOFH_00579	7.92e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HFFBLOFH_00580	1.15e-94	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HFFBLOFH_00581	3.14e-109	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HFFBLOFH_00582	4.81e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HFFBLOFH_00583	9.21e-94	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HFFBLOFH_00584	1.09e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HFFBLOFH_00585	2.32e-194	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HFFBLOFH_00586	1.78e-140	-	-	-	C	-	-	-	Enoyl-(Acyl carrier protein) reductase
HFFBLOFH_00587	1.42e-217	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HFFBLOFH_00588	1.84e-284	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HFFBLOFH_00589	4.35e-204	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HFFBLOFH_00590	2.61e-132	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HFFBLOFH_00591	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HFFBLOFH_00592	2.47e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HFFBLOFH_00593	4.01e-200	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
HFFBLOFH_00594	2.29e-207	-	-	-	G	-	-	-	Fructosamine kinase
HFFBLOFH_00595	2.43e-150	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
HFFBLOFH_00596	8.2e-102	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HFFBLOFH_00597	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HFFBLOFH_00598	2.56e-76	-	-	-	-	-	-	-	-
HFFBLOFH_00599	3.13e-172	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HFFBLOFH_00600	2.04e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HFFBLOFH_00601	5.28e-146	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HFFBLOFH_00602	4.78e-65	-	-	-	-	-	-	-	-
HFFBLOFH_00603	1.73e-67	-	-	-	-	-	-	-	-
HFFBLOFH_00606	1.01e-158	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HFFBLOFH_00607	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HFFBLOFH_00608	1.68e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HFFBLOFH_00609	5.75e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFFBLOFH_00610	3.27e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HFFBLOFH_00611	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFFBLOFH_00612	8.59e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HFFBLOFH_00613	8.49e-266	pbpX2	-	-	V	-	-	-	Beta-lactamase
HFFBLOFH_00614	2.54e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HFFBLOFH_00615	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HFFBLOFH_00616	4.52e-111	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HFFBLOFH_00617	4.42e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HFFBLOFH_00618	1.19e-169	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HFFBLOFH_00619	2.53e-240	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HFFBLOFH_00620	8.94e-221	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HFFBLOFH_00621	2.41e-113	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HFFBLOFH_00622	1.21e-245	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HFFBLOFH_00623	1.19e-285	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HFFBLOFH_00624	1.63e-121	-	-	-	-	-	-	-	-
HFFBLOFH_00625	3.67e-275	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HFFBLOFH_00626	0.0	-	-	-	G	-	-	-	Major Facilitator
HFFBLOFH_00627	3.04e-71	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HFFBLOFH_00628	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HFFBLOFH_00629	3.28e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
HFFBLOFH_00630	2.95e-65	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HFFBLOFH_00631	4.46e-275	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HFFBLOFH_00632	9.74e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HFFBLOFH_00633	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFFBLOFH_00634	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HFFBLOFH_00635	4.64e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HFFBLOFH_00636	1.13e-175	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HFFBLOFH_00637	3.17e-190	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HFFBLOFH_00638	9.83e-113	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HFFBLOFH_00639	3.01e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HFFBLOFH_00640	1.88e-194	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HFFBLOFH_00641	6.33e-185	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HFFBLOFH_00642	2.92e-172	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
HFFBLOFH_00643	1.92e-239	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFFBLOFH_00644	5.67e-64	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HFFBLOFH_00645	2.11e-171	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HFFBLOFH_00646	8.8e-155	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HFFBLOFH_00647	3.96e-44	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HFFBLOFH_00648	7.68e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
HFFBLOFH_00649	7.22e-149	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HFFBLOFH_00650	7.8e-123	-	-	-	-	-	-	-	-
HFFBLOFH_00651	1.56e-276	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HFFBLOFH_00652	1.38e-98	-	-	-	-	-	-	-	-
HFFBLOFH_00653	3.81e-87	-	-	-	-	-	-	-	-
HFFBLOFH_00654	1.14e-226	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family 2
HFFBLOFH_00655	2.19e-131	-	-	-	L	-	-	-	Helix-turn-helix domain
HFFBLOFH_00656	4.46e-281	ywtF_2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HFFBLOFH_00657	3.82e-184	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HFFBLOFH_00658	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HFFBLOFH_00659	1.96e-293	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Cell cycle protein
HFFBLOFH_00661	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HFFBLOFH_00662	3.67e-154	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HFFBLOFH_00663	2.38e-140	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HFFBLOFH_00664	9.82e-55	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HFFBLOFH_00665	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HFFBLOFH_00666	0.0	ydaO	-	-	E	-	-	-	amino acid
HFFBLOFH_00667	7.29e-247	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
HFFBLOFH_00668	6.57e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HFFBLOFH_00669	3.7e-149	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HFFBLOFH_00670	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HFFBLOFH_00671	2.94e-164	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HFFBLOFH_00672	1.27e-129	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HFFBLOFH_00673	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HFFBLOFH_00674	3.41e-257	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HFFBLOFH_00675	1.05e-275	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HFFBLOFH_00676	1.49e-170	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HFFBLOFH_00677	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFFBLOFH_00678	2.31e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HFFBLOFH_00679	9.05e-206	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HFFBLOFH_00680	5.04e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HFFBLOFH_00681	9.78e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HFFBLOFH_00682	4.47e-177	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HFFBLOFH_00683	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HFFBLOFH_00684	2.78e-65	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
HFFBLOFH_00685	2.87e-71	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HFFBLOFH_00686	2.55e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HFFBLOFH_00687	6.26e-213	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HFFBLOFH_00688	4e-235	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HFFBLOFH_00689	1.13e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HFFBLOFH_00690	6.37e-160	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HFFBLOFH_00691	0.0	nox	-	-	C	-	-	-	NADH oxidase
HFFBLOFH_00692	8.65e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HFFBLOFH_00693	4.31e-141	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HFFBLOFH_00694	7.54e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HFFBLOFH_00695	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HFFBLOFH_00696	5.9e-170	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HFFBLOFH_00697	0.0	nox2	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HFFBLOFH_00698	1.89e-134	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HFFBLOFH_00699	5.33e-268	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
HFFBLOFH_00700	3.85e-151	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HFFBLOFH_00701	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HFFBLOFH_00702	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HFFBLOFH_00703	2.21e-113	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HFFBLOFH_00704	7.5e-302	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HFFBLOFH_00705	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HFFBLOFH_00706	3.51e-113	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HFFBLOFH_00707	1.71e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HFFBLOFH_00708	5.32e-242	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HFFBLOFH_00709	1.21e-215	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HFFBLOFH_00710	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFFBLOFH_00711	8.58e-223	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFFBLOFH_00712	5.11e-133	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HFFBLOFH_00714	1.14e-311	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
HFFBLOFH_00715	5.75e-242	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HFFBLOFH_00716	2.02e-245	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HFFBLOFH_00717	1.31e-285	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HFFBLOFH_00718	7.15e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HFFBLOFH_00719	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HFFBLOFH_00720	2.83e-168	-	-	-	-	-	-	-	-
HFFBLOFH_00721	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HFFBLOFH_00722	3.55e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HFFBLOFH_00723	3.83e-179	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
HFFBLOFH_00724	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HFFBLOFH_00725	2.4e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HFFBLOFH_00726	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HFFBLOFH_00727	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFFBLOFH_00728	9.36e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFFBLOFH_00729	7.98e-137	-	-	-	-	-	-	-	-
HFFBLOFH_00730	1.98e-199	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HFFBLOFH_00731	1.4e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HFFBLOFH_00732	1.23e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HFFBLOFH_00733	1.29e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HFFBLOFH_00734	2.52e-114	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HFFBLOFH_00735	2.41e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HFFBLOFH_00736	2.53e-198	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HFFBLOFH_00737	3.09e-213	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
HFFBLOFH_00738	6.24e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HFFBLOFH_00739	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HFFBLOFH_00740	3.07e-119	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HFFBLOFH_00741	8.06e-156	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
HFFBLOFH_00742	2.39e-191	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HFFBLOFH_00743	2.18e-182	ybbR	-	-	S	-	-	-	YbbR-like protein
HFFBLOFH_00744	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HFFBLOFH_00745	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HFFBLOFH_00746	8.59e-85	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HFFBLOFH_00747	1.13e-182	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HFFBLOFH_00748	3.66e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HFFBLOFH_00749	3.3e-202	degV1	-	-	S	-	-	-	DegV family
HFFBLOFH_00750	2.89e-80	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
HFFBLOFH_00751	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HFFBLOFH_00753	2.76e-141	sip3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HFFBLOFH_00754	0.0	-	-	-	-	-	-	-	-
HFFBLOFH_00756	2.13e-209	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HFFBLOFH_00757	2.16e-142	-	-	-	S	-	-	-	Cell surface protein
HFFBLOFH_00758	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HFFBLOFH_00759	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HFFBLOFH_00760	2.14e-155	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HFFBLOFH_00761	3.75e-305	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
HFFBLOFH_00762	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFFBLOFH_00763	1.55e-158	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HFFBLOFH_00764	3.74e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HFFBLOFH_00765	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HFFBLOFH_00766	8.19e-267	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HFFBLOFH_00767	3.82e-51	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HFFBLOFH_00768	7.24e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HFFBLOFH_00769	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFFBLOFH_00770	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFFBLOFH_00771	5.95e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HFFBLOFH_00772	1.59e-95	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HFFBLOFH_00773	2.69e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HFFBLOFH_00774	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HFFBLOFH_00775	3.44e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HFFBLOFH_00776	8.77e-317	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HFFBLOFH_00777	4.96e-289	yttB	-	-	EGP	-	-	-	Major Facilitator
HFFBLOFH_00778	9e-184	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HFFBLOFH_00779	2.19e-290	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HFFBLOFH_00781	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFFBLOFH_00782	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HFFBLOFH_00783	6.65e-282	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HFFBLOFH_00784	3.49e-269	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HFFBLOFH_00785	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HFFBLOFH_00786	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HFFBLOFH_00787	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HFFBLOFH_00788	8.38e-184	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HFFBLOFH_00789	1.1e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HFFBLOFH_00790	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
HFFBLOFH_00791	3.21e-104	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
HFFBLOFH_00792	4.37e-43	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein domain
HFFBLOFH_00793	2.54e-50	-	-	-	-	-	-	-	-
HFFBLOFH_00795	2.22e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HFFBLOFH_00796	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFFBLOFH_00797	3.55e-313	yycH	-	-	S	-	-	-	YycH protein
HFFBLOFH_00798	3.54e-195	yycI	-	-	S	-	-	-	YycH protein
HFFBLOFH_00799	1.71e-200	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HFFBLOFH_00800	1.5e-253	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HFFBLOFH_00801	6.08e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HFFBLOFH_00802	3.46e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFFBLOFH_00803	0.0	-	-	-	C	-	-	-	Belongs to the aldehyde dehydrogenase family
HFFBLOFH_00804	6.96e-214	-	-	-	L	-	-	-	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HFFBLOFH_00805	5.97e-157	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HFFBLOFH_00806	4.75e-42	pnb	-	-	C	-	-	-	nitroreductase
HFFBLOFH_00807	5.63e-86	pnb	-	-	C	-	-	-	nitroreductase
HFFBLOFH_00808	4.95e-86	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
HFFBLOFH_00809	1.57e-150	-	-	-	S	-	-	-	Elongation factor G-binding protein, N-terminal
HFFBLOFH_00810	0.0	-	-	-	C	-	-	-	FMN_bind
HFFBLOFH_00811	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HFFBLOFH_00812	1.46e-204	-	-	-	K	-	-	-	LysR family
HFFBLOFH_00813	2.49e-95	-	-	-	C	-	-	-	FMN binding
HFFBLOFH_00814	4.48e-98	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HFFBLOFH_00815	4.06e-211	-	-	-	S	-	-	-	KR domain
HFFBLOFH_00816	5.74e-204	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
HFFBLOFH_00817	5.07e-157	ydgI	-	-	C	-	-	-	Nitroreductase family
HFFBLOFH_00818	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HFFBLOFH_00819	1.56e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HFFBLOFH_00820	7.63e-249	pva1	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HFFBLOFH_00821	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HFFBLOFH_00822	6.86e-175	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HFFBLOFH_00823	0.0	hpaH	1.14.14.8, 1.14.14.9	-	Q	ko:K00483,ko:K16901	ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220	ko00000,ko00001,ko01000	4-hydroxyphenylacetate
HFFBLOFH_00824	1.65e-106	-	-	-	S	-	-	-	ASCH
HFFBLOFH_00825	1.25e-164	-	-	-	F	-	-	-	glutamine amidotransferase
HFFBLOFH_00826	1.67e-220	-	-	-	K	-	-	-	WYL domain
HFFBLOFH_00827	1.63e-152	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HFFBLOFH_00828	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HFFBLOFH_00829	7.44e-51	-	-	-	S	-	-	-	Protein of unknown function
HFFBLOFH_00830	2.7e-79	-	-	-	S	-	-	-	Protein of unknown function
HFFBLOFH_00831	8.64e-195	-	-	-	EG	-	-	-	EamA-like transporter family
HFFBLOFH_00832	7.65e-121	yfbM	-	-	K	-	-	-	FR47-like protein
HFFBLOFH_00833	1.4e-162	-	-	-	S	-	-	-	DJ-1/PfpI family
HFFBLOFH_00834	3.14e-230	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HFFBLOFH_00835	1.92e-67	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HFFBLOFH_00836	5.98e-302	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HFFBLOFH_00837	2.91e-29	-	-	-	-	-	-	-	-
HFFBLOFH_00838	1.93e-102	-	-	-	-	-	-	-	-
HFFBLOFH_00842	4.43e-168	-	-	-	S	-	-	-	Phage minor structural protein
HFFBLOFH_00843	0.0	-	-	-	S	-	-	-	Phage tail protein
HFFBLOFH_00844	0.0	-	-	-	D	-	-	-	domain protein
HFFBLOFH_00845	6.36e-34	-	-	-	-	-	-	-	-
HFFBLOFH_00846	1.35e-75	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
HFFBLOFH_00847	2.16e-131	-	-	-	S	-	-	-	Phage tail tube protein
HFFBLOFH_00848	7.47e-74	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
HFFBLOFH_00849	2.25e-86	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HFFBLOFH_00850	3.45e-76	-	-	-	S	-	-	-	Phage head-tail joining protein
HFFBLOFH_00851	9.36e-65	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HFFBLOFH_00852	1.03e-254	-	-	-	S	-	-	-	Phage capsid family
HFFBLOFH_00853	5.99e-164	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HFFBLOFH_00854	6.97e-284	-	-	-	S	-	-	-	Phage portal protein
HFFBLOFH_00855	6.68e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF1056)
HFFBLOFH_00856	0.0	-	-	-	S	-	-	-	Phage Terminase
HFFBLOFH_00857	6.68e-103	-	-	-	L	-	-	-	Phage terminase, small subunit
HFFBLOFH_00859	7.81e-113	-	-	-	L	-	-	-	HNH nucleases
HFFBLOFH_00860	1.26e-12	-	-	-	-	-	-	-	-
HFFBLOFH_00861	1.13e-84	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
HFFBLOFH_00862	2.2e-23	-	-	-	-	-	-	-	-
HFFBLOFH_00863	5.27e-72	-	-	-	-	-	-	-	-
HFFBLOFH_00864	1.28e-09	-	-	-	S	-	-	-	YopX protein
HFFBLOFH_00866	8.89e-118	-	-	-	L	-	-	-	C-5 cytosine-specific DNA methylase
HFFBLOFH_00868	2.95e-06	-	-	-	-	-	-	-	-
HFFBLOFH_00869	4.01e-87	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HFFBLOFH_00871	2.84e-169	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
HFFBLOFH_00872	6.11e-56	-	-	-	L	-	-	-	DnaD domain protein
HFFBLOFH_00873	2.93e-167	-	-	-	S	-	-	-	Putative HNHc nuclease
HFFBLOFH_00874	3.13e-127	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
HFFBLOFH_00875	3.98e-151	-	-	-	S	-	-	-	AAA domain
HFFBLOFH_00876	4.24e-188	-	-	-	S	-	-	-	Protein of unknown function (DUF1351)
HFFBLOFH_00878	2e-25	-	-	-	-	-	-	-	-
HFFBLOFH_00885	7.34e-80	-	-	-	S	-	-	-	DNA binding
HFFBLOFH_00888	1.56e-27	-	-	-	-	-	-	-	-
HFFBLOFH_00889	2.59e-99	-	-	-	K	-	-	-	Peptidase S24-like
HFFBLOFH_00896	6.15e-75	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HFFBLOFH_00897	5.03e-43	-	-	-	-	-	-	-	-
HFFBLOFH_00898	2.21e-178	-	-	-	Q	-	-	-	Methyltransferase
HFFBLOFH_00899	2.84e-75	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
HFFBLOFH_00900	1.66e-269	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HFFBLOFH_00901	3.58e-129	-	-	-	K	-	-	-	Helix-turn-helix domain
HFFBLOFH_00902	1.52e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HFFBLOFH_00903	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HFFBLOFH_00904	1.84e-67	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HFFBLOFH_00905	7.09e-180	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFFBLOFH_00906	8.34e-228	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HFFBLOFH_00907	6.62e-62	-	-	-	-	-	-	-	-
HFFBLOFH_00908	1.55e-311	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HFFBLOFH_00909	3.02e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HFFBLOFH_00910	4.24e-218	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HFFBLOFH_00911	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HFFBLOFH_00912	0.0	-	3.1.4.53	-	S	ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HFFBLOFH_00913	0.0	cps4J	-	-	S	-	-	-	MatE
HFFBLOFH_00914	4.82e-228	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
HFFBLOFH_00915	1.91e-297	-	-	-	-	-	-	-	-
HFFBLOFH_00916	7.88e-48	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
HFFBLOFH_00917	1.82e-132	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
HFFBLOFH_00918	1.43e-223	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
HFFBLOFH_00919	3.18e-162	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
HFFBLOFH_00920	8.71e-231	cps4D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HFFBLOFH_00921	5.54e-189	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HFFBLOFH_00922	2.02e-156	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HFFBLOFH_00923	8.45e-162	epsB	-	-	M	-	-	-	biosynthesis protein
HFFBLOFH_00924	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HFFBLOFH_00925	3.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFFBLOFH_00926	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HFFBLOFH_00927	5.12e-31	-	-	-	-	-	-	-	-
HFFBLOFH_00928	6.47e-95	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HFFBLOFH_00929	1.3e-65	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HFFBLOFH_00930	9.6e-143	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HFFBLOFH_00931	7.8e-300	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HFFBLOFH_00932	3.21e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HFFBLOFH_00933	4.38e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HFFBLOFH_00934	9.34e-201	-	-	-	S	-	-	-	Tetratricopeptide repeat
HFFBLOFH_00935	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HFFBLOFH_00936	1.29e-200	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HFFBLOFH_00937	1.8e-135	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HFFBLOFH_00938	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HFFBLOFH_00939	1.18e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HFFBLOFH_00940	8.43e-240	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HFFBLOFH_00941	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HFFBLOFH_00942	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HFFBLOFH_00943	2.1e-161	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HFFBLOFH_00944	1.05e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HFFBLOFH_00945	7.04e-108	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HFFBLOFH_00946	8.61e-132	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HFFBLOFH_00947	1.91e-66	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HFFBLOFH_00948	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HFFBLOFH_00949	1.45e-260	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HFFBLOFH_00950	0.0	-	-	-	-	-	-	-	-
HFFBLOFH_00951	1.56e-262	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
HFFBLOFH_00952	2.81e-194	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HFFBLOFH_00953	9.06e-112	-	-	-	-	-	-	-	-
HFFBLOFH_00954	2.05e-179	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HFFBLOFH_00955	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HFFBLOFH_00957	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
HFFBLOFH_00958	8.08e-135	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
HFFBLOFH_00959	6.03e-226	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HFFBLOFH_00960	2.41e-165	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HFFBLOFH_00961	1.57e-142	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HFFBLOFH_00962	5.13e-287	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HFFBLOFH_00963	4.82e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HFFBLOFH_00964	5.89e-126	entB	-	-	Q	-	-	-	Isochorismatase family
HFFBLOFH_00965	1.36e-210	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
HFFBLOFH_00966	1.95e-88	ybbJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HFFBLOFH_00967	1.62e-276	-	-	-	E	-	-	-	glutamate:sodium symporter activity
HFFBLOFH_00968	3.38e-274	hipO1	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	Peptidase family M20/M25/M40
HFFBLOFH_00969	2.69e-252	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HFFBLOFH_00970	1.49e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HFFBLOFH_00972	6.84e-186	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFFBLOFH_00973	1.62e-229	yneE	-	-	K	-	-	-	Transcriptional regulator
HFFBLOFH_00974	8.55e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HFFBLOFH_00975	1.62e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HFFBLOFH_00976	6.16e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HFFBLOFH_00977	3.47e-215	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HFFBLOFH_00978	1.26e-162	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HFFBLOFH_00979	1.8e-288	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HFFBLOFH_00980	2.14e-95	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HFFBLOFH_00981	1.71e-91	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HFFBLOFH_00982	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HFFBLOFH_00983	6.43e-203	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HFFBLOFH_00984	4.82e-179	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HFFBLOFH_00985	2.29e-175	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HFFBLOFH_00986	5.01e-129	-	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
HFFBLOFH_00987	1.48e-161	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HFFBLOFH_00988	7.52e-207	-	-	-	K	-	-	-	LysR substrate binding domain
HFFBLOFH_00989	2.01e-113	ykhA	-	-	I	-	-	-	Thioesterase superfamily
HFFBLOFH_00990	4.4e-246	rsgA_2	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HFFBLOFH_00991	4.09e-119	-	-	-	K	-	-	-	transcriptional regulator
HFFBLOFH_00992	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HFFBLOFH_00993	1.14e-193	-	-	-	O	-	-	-	Band 7 protein
HFFBLOFH_00994	1.48e-71	-	-	-	-	-	-	-	-
HFFBLOFH_00995	2.02e-39	-	-	-	-	-	-	-	-
HFFBLOFH_00996	6.57e-274	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HFFBLOFH_00997	3.2e-37	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HFFBLOFH_00998	9.96e-147	-	1.14.99.53	AA10	S	ko:K21713	-	ko00000,ko01000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
HFFBLOFH_00999	5.93e-60	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HFFBLOFH_01000	2.05e-55	-	-	-	-	-	-	-	-
HFFBLOFH_01001	6.05e-108	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
HFFBLOFH_01002	5.28e-100	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HFFBLOFH_01003	5.58e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HFFBLOFH_01004	1.21e-209	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HFFBLOFH_01005	8.76e-48	-	-	-	-	-	-	-	-
HFFBLOFH_01006	5.79e-21	-	-	-	-	-	-	-	-
HFFBLOFH_01007	2.22e-55	-	-	-	S	-	-	-	transglycosylase associated protein
HFFBLOFH_01008	4e-40	-	-	-	S	-	-	-	CsbD-like
HFFBLOFH_01009	1.06e-53	-	-	-	-	-	-	-	-
HFFBLOFH_01010	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HFFBLOFH_01011	8.39e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HFFBLOFH_01012	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HFFBLOFH_01013	1.48e-218	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HFFBLOFH_01014	5.03e-182	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
HFFBLOFH_01015	1.25e-66	-	-	-	-	-	-	-	-
HFFBLOFH_01016	1.54e-56	-	-	-	-	-	-	-	-
HFFBLOFH_01017	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HFFBLOFH_01018	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HFFBLOFH_01019	3.86e-192	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HFFBLOFH_01020	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HFFBLOFH_01021	3.24e-155	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HFFBLOFH_01022	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HFFBLOFH_01023	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HFFBLOFH_01024	3.36e-247	galM2	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HFFBLOFH_01025	8.61e-251	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HFFBLOFH_01026	2.94e-261	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HFFBLOFH_01027	1.1e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HFFBLOFH_01028	1.48e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HFFBLOFH_01029	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HFFBLOFH_01030	2.53e-107	ypmB	-	-	S	-	-	-	protein conserved in bacteria
HFFBLOFH_01031	3.1e-289	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HFFBLOFH_01032	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HFFBLOFH_01033	9.32e-165	dnaD	-	-	L	ko:K02086	-	ko00000	Replication initiation and membrane attachment
HFFBLOFH_01035	2.32e-238	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HFFBLOFH_01036	2.45e-142	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFFBLOFH_01037	1.58e-203	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HFFBLOFH_01038	5.32e-109	-	-	-	T	-	-	-	Universal stress protein family
HFFBLOFH_01039	0.0	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HFFBLOFH_01040	8.06e-234	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HFFBLOFH_01041	4.64e-228	phnT	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HFFBLOFH_01042	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HFFBLOFH_01043	3.6e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HFFBLOFH_01044	2.12e-142	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HFFBLOFH_01045	9.98e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HFFBLOFH_01047	1.44e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HFFBLOFH_01048	1.26e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HFFBLOFH_01049	1.55e-309	-	-	-	P	-	-	-	Major Facilitator Superfamily
HFFBLOFH_01050	4.17e-186	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HFFBLOFH_01051	9.19e-95	-	-	-	S	-	-	-	SnoaL-like domain
HFFBLOFH_01052	9.63e-307	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HFFBLOFH_01053	3.46e-267	mccF	-	-	V	-	-	-	LD-carboxypeptidase
HFFBLOFH_01054	1.66e-101	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HFFBLOFH_01055	1.46e-170	-	-	-	-	-	-	-	-
HFFBLOFH_01056	2.72e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HFFBLOFH_01057	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HFFBLOFH_01058	7.79e-112	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HFFBLOFH_01059	1.36e-77	-	-	-	-	-	-	-	-
HFFBLOFH_01060	2.94e-155	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HFFBLOFH_01061	1.78e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HFFBLOFH_01062	4.6e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
HFFBLOFH_01063	7.76e-100	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HFFBLOFH_01064	2.34e-242	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HFFBLOFH_01065	4.15e-153	-	-	-	I	-	-	-	phosphatase
HFFBLOFH_01066	3.88e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HFFBLOFH_01067	3.03e-129	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HFFBLOFH_01068	5.68e-117	-	-	-	K	-	-	-	Transcriptional regulator
HFFBLOFH_01069	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HFFBLOFH_01070	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HFFBLOFH_01071	7.48e-153	dacB	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HFFBLOFH_01072	1.11e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HFFBLOFH_01073	1.62e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HFFBLOFH_01080	9.78e-102	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HFFBLOFH_01081	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HFFBLOFH_01082	1.16e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFFBLOFH_01083	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFFBLOFH_01084	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFFBLOFH_01085	1.48e-149	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HFFBLOFH_01086	4.19e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HFFBLOFH_01087	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HFFBLOFH_01088	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HFFBLOFH_01089	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HFFBLOFH_01090	1.24e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HFFBLOFH_01091	9.83e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HFFBLOFH_01092	2.27e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HFFBLOFH_01093	6.61e-193	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HFFBLOFH_01094	1.85e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HFFBLOFH_01095	3.59e-69	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HFFBLOFH_01096	5.46e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HFFBLOFH_01097	8.29e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HFFBLOFH_01098	1.11e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HFFBLOFH_01099	1.96e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HFFBLOFH_01100	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HFFBLOFH_01101	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HFFBLOFH_01102	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HFFBLOFH_01103	4.99e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HFFBLOFH_01104	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HFFBLOFH_01105	1.75e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HFFBLOFH_01106	5.32e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HFFBLOFH_01107	8.44e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HFFBLOFH_01108	1.32e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HFFBLOFH_01109	5.95e-300	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HFFBLOFH_01110	1.84e-160	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HFFBLOFH_01111	9.87e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HFFBLOFH_01112	9.65e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HFFBLOFH_01113	7.71e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HFFBLOFH_01114	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFFBLOFH_01115	7.76e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HFFBLOFH_01116	1.02e-233	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HFFBLOFH_01117	1.41e-122	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
HFFBLOFH_01118	4.42e-111	-	-	-	S	-	-	-	NusG domain II
HFFBLOFH_01119	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HFFBLOFH_01120	3.19e-194	-	-	-	S	-	-	-	FMN_bind
HFFBLOFH_01121	3.08e-264	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HFFBLOFH_01122	1.98e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFFBLOFH_01123	2.01e-211	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFFBLOFH_01124	2.29e-182	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFFBLOFH_01125	3.06e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HFFBLOFH_01126	4.58e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HFFBLOFH_01127	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HFFBLOFH_01128	8.51e-210	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HFFBLOFH_01129	1.68e-221	-	-	-	S	-	-	-	Membrane
HFFBLOFH_01130	9.14e-38	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HFFBLOFH_01131	2.99e-208	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HFFBLOFH_01132	0.0	tkt2	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HFFBLOFH_01133	1.65e-211	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HFFBLOFH_01134	3.3e-235	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	DAHP synthetase I family
HFFBLOFH_01135	1.33e-255	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HFFBLOFH_01137	1.49e-281	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HFFBLOFH_01138	1.51e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HFFBLOFH_01139	1.41e-147	-	4.2.1.2, 4.2.1.32	-	C	ko:K01676,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
HFFBLOFH_01140	4.28e-225	ttdA	4.2.1.32	-	C	ko:K03779	ko00630,map00630	ko00000,ko00001,ko01000	Fumarate hydratase (Fumerase)
HFFBLOFH_01141	6.07e-252	-	-	-	K	-	-	-	Helix-turn-helix domain
HFFBLOFH_01142	3.16e-196	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HFFBLOFH_01143	2.04e-170	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HFFBLOFH_01144	1.76e-180	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HFFBLOFH_01145	4.26e-222	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HFFBLOFH_01146	1.18e-66	-	-	-	-	-	-	-	-
HFFBLOFH_01147	9.2e-215	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HFFBLOFH_01148	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HFFBLOFH_01149	8.69e-230	citR	-	-	K	-	-	-	sugar-binding domain protein
HFFBLOFH_01150	1.11e-263	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
HFFBLOFH_01151	3.07e-241	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HFFBLOFH_01152	1.23e-58	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
HFFBLOFH_01153	1.51e-206	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
HFFBLOFH_01154	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
HFFBLOFH_01155	3.62e-249	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HFFBLOFH_01156	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HFFBLOFH_01157	4.66e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HFFBLOFH_01158	6.84e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HFFBLOFH_01159	3.46e-242	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HFFBLOFH_01160	3.8e-176	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HFFBLOFH_01161	2.18e-176	phnE2	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter permease
HFFBLOFH_01162	3.33e-184	phnE1	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFFBLOFH_01163	2.8e-187	phnX	3.11.1.1	-	E	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the HAD-like hydrolase superfamily. PhnX family
HFFBLOFH_01164	5.35e-270	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HFFBLOFH_01165	4.95e-246	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HFFBLOFH_01166	1.29e-190	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HFFBLOFH_01167	2.64e-213	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HFFBLOFH_01168	8.46e-77	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HFFBLOFH_01169	2.33e-239	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HFFBLOFH_01170	1.39e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HFFBLOFH_01171	1.82e-152	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HFFBLOFH_01172	1.01e-51	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HFFBLOFH_01173	6.22e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HFFBLOFH_01174	8.34e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HFFBLOFH_01175	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFFBLOFH_01176	7.57e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HFFBLOFH_01177	6.7e-141	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HFFBLOFH_01178	8.42e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HFFBLOFH_01179	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFFBLOFH_01180	2.47e-253	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFFBLOFH_01181	2.37e-140	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HFFBLOFH_01182	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HFFBLOFH_01183	4.82e-86	-	-	-	L	-	-	-	nuclease
HFFBLOFH_01184	1.01e-226	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HFFBLOFH_01185	2.76e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HFFBLOFH_01186	3.72e-105	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HFFBLOFH_01187	2.69e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HFFBLOFH_01188	9.76e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HFFBLOFH_01189	2.81e-202	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HFFBLOFH_01190	1.89e-128	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HFFBLOFH_01191	1e-39	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HFFBLOFH_01192	4.55e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HFFBLOFH_01193	1.12e-130	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
HFFBLOFH_01194	1.44e-125	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
HFFBLOFH_01195	1.49e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFFBLOFH_01196	1.35e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HFFBLOFH_01197	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HFFBLOFH_01198	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HFFBLOFH_01199	4.91e-265	yacL	-	-	S	-	-	-	domain protein
HFFBLOFH_01200	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HFFBLOFH_01201	9.43e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HFFBLOFH_01202	5.96e-69	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HFFBLOFH_01203	1.62e-158	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HFFBLOFH_01204	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HFFBLOFH_01205	3.22e-147	zmp2	-	-	O	-	-	-	Zinc-dependent metalloprotease
HFFBLOFH_01206	1.91e-165	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HFFBLOFH_01207	1.22e-226	-	-	-	EG	-	-	-	EamA-like transporter family
HFFBLOFH_01208	3.06e-214	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HFFBLOFH_01209	5.37e-233	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HFFBLOFH_01210	1.05e-172	accA1	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
HFFBLOFH_01211	1.49e-183	accD1	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HFFBLOFH_01212	1.7e-315	accC1	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
HFFBLOFH_01213	9.24e-85	accB1	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin-requiring enzyme
HFFBLOFH_01214	3.15e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HFFBLOFH_01215	4.5e-113	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HFFBLOFH_01216	4.16e-93	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HFFBLOFH_01217	0.0	levR	-	-	K	-	-	-	Sigma-54 interaction domain
HFFBLOFH_01218	9.05e-85	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
HFFBLOFH_01219	4.22e-216	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HFFBLOFH_01220	4.51e-172	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HFFBLOFH_01221	6.46e-218	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HFFBLOFH_01222	1.53e-195	-	-	-	G	-	-	-	Peptidase_C39 like family
HFFBLOFH_01224	1.9e-198	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HFFBLOFH_01225	1.71e-302	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HFFBLOFH_01226	3.09e-106	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HFFBLOFH_01227	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HFFBLOFH_01228	2.57e-94	-	-	-	-	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	-
HFFBLOFH_01229	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HFFBLOFH_01230	1.51e-196	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HFFBLOFH_01231	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HFFBLOFH_01232	5.44e-175	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HFFBLOFH_01233	5.41e-160	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HFFBLOFH_01234	2.92e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HFFBLOFH_01235	2.18e-174	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HFFBLOFH_01236	1.06e-195	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HFFBLOFH_01237	1.59e-247	ysdE	-	-	P	-	-	-	Citrate transporter
HFFBLOFH_01238	3.1e-212	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
HFFBLOFH_01239	1.38e-71	-	-	-	S	-	-	-	Cupin domain
HFFBLOFH_01240	9.02e-66	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
HFFBLOFH_01244	1.75e-193	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HFFBLOFH_01245	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HFFBLOFH_01247	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HFFBLOFH_01248	1.56e-46	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HFFBLOFH_01249	3.91e-289	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HFFBLOFH_01250	2.29e-292	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HFFBLOFH_01251	2.16e-241	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HFFBLOFH_01252	2.04e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HFFBLOFH_01253	1.41e-285	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HFFBLOFH_01254	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HFFBLOFH_01255	1.24e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HFFBLOFH_01256	5.6e-41	-	-	-	-	-	-	-	-
HFFBLOFH_01257	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HFFBLOFH_01258	3.29e-95	-	-	-	L	-	-	-	Integrase
HFFBLOFH_01259	3.4e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HFFBLOFH_01260	5.67e-231	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFFBLOFH_01261	4.86e-258	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFFBLOFH_01262	3.59e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFFBLOFH_01263	3.44e-210	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFFBLOFH_01264	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFFBLOFH_01265	3.85e-76	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
HFFBLOFH_01266	1.01e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HFFBLOFH_01267	1.36e-208	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HFFBLOFH_01268	1.01e-250	-	-	-	M	-	-	-	MucBP domain
HFFBLOFH_01269	0.0	-	-	-	-	-	-	-	-
HFFBLOFH_01270	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HFFBLOFH_01271	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HFFBLOFH_01272	1.22e-218	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HFFBLOFH_01273	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HFFBLOFH_01274	7.89e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HFFBLOFH_01275	6.04e-94	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HFFBLOFH_01276	1.13e-257	yueF	-	-	S	-	-	-	AI-2E family transporter
HFFBLOFH_01277	7.3e-216	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HFFBLOFH_01278	7.17e-39	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HFFBLOFH_01279	3.97e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
HFFBLOFH_01280	1.94e-170	lytE	-	-	M	-	-	-	NlpC/P60 family
HFFBLOFH_01281	6.62e-138	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HFFBLOFH_01282	1.01e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HFFBLOFH_01283	1.34e-168	-	-	-	-	-	-	-	-
HFFBLOFH_01284	1.68e-131	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HFFBLOFH_01285	3.31e-35	-	-	-	-	-	-	-	-
HFFBLOFH_01286	1.95e-41	-	-	-	-	-	-	-	-
HFFBLOFH_01287	1.04e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HFFBLOFH_01288	9.02e-70	-	-	-	-	-	-	-	-
HFFBLOFH_01290	3.98e-169	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HFFBLOFH_01291	1.95e-197	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HFFBLOFH_01292	3.34e-267	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HFFBLOFH_01293	3.3e-281	pbpX	-	-	V	-	-	-	Beta-lactamase
HFFBLOFH_01294	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HFFBLOFH_01295	8.31e-139	-	-	-	-	-	-	-	-
HFFBLOFH_01296	7.62e-97	-	-	-	-	-	-	-	-
HFFBLOFH_01298	3.21e-209	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HFFBLOFH_01299	3.15e-313	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFFBLOFH_01300	3.93e-99	-	-	-	T	-	-	-	Universal stress protein family
HFFBLOFH_01302	5.62e-316	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HFFBLOFH_01303	7.89e-245	mocA	-	-	S	-	-	-	Oxidoreductase
HFFBLOFH_01304	6.22e-43	cspP	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HFFBLOFH_01305	7.34e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HFFBLOFH_01306	2.22e-185	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HFFBLOFH_01307	5.63e-196	gntR	-	-	K	-	-	-	rpiR family
HFFBLOFH_01308	2.87e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HFFBLOFH_01309	7.06e-307	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFFBLOFH_01310	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HFFBLOFH_01311	2.26e-129	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFFBLOFH_01312	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFFBLOFH_01313	1.59e-242	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HFFBLOFH_01314	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFFBLOFH_01315	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HFFBLOFH_01316	5.11e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFFBLOFH_01317	9.48e-263	camS	-	-	S	-	-	-	sex pheromone
HFFBLOFH_01318	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HFFBLOFH_01319	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HFFBLOFH_01320	1.39e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HFFBLOFH_01321	1.13e-120	yebE	-	-	S	-	-	-	UPF0316 protein
HFFBLOFH_01322	2.01e-134	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HFFBLOFH_01323	1.97e-145	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HFFBLOFH_01324	7.78e-235	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HFFBLOFH_01325	1.37e-83	-	-	-	K	-	-	-	Helix-turn-helix domain
HFFBLOFH_01326	1.08e-71	-	-	-	-	-	-	-	-
HFFBLOFH_01327	1.66e-96	-	-	-	-	-	-	-	-
HFFBLOFH_01328	6.67e-30	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HFFBLOFH_01329	8.56e-38	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HFFBLOFH_01330	9.16e-61	-	-	-	L	-	-	-	Helix-turn-helix domain
HFFBLOFH_01332	3.56e-171	spoVK	-	-	O	ko:K06413	-	ko00000	ATPase family associated with various cellular activities (AAA)
HFFBLOFH_01334	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HFFBLOFH_01335	1.22e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HFFBLOFH_01336	8.45e-211	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
HFFBLOFH_01337	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HFFBLOFH_01338	4.51e-143	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HFFBLOFH_01339	4.16e-227	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HFFBLOFH_01340	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HFFBLOFH_01341	2.07e-161	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
HFFBLOFH_01342	1.35e-165	pgm3	-	-	G	-	-	-	Phosphoglycerate mutase family
HFFBLOFH_01343	1.61e-36	-	-	-	-	-	-	-	-
HFFBLOFH_01344	3.5e-64	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
HFFBLOFH_01345	4.6e-102	rppH3	-	-	F	-	-	-	NUDIX domain
HFFBLOFH_01346	5.95e-300	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HFFBLOFH_01347	1.81e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFFBLOFH_01348	2.93e-109	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HFFBLOFH_01349	3.22e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HFFBLOFH_01350	7.26e-92	-	-	-	K	-	-	-	MarR family
HFFBLOFH_01351	8.87e-191	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
HFFBLOFH_01352	6.26e-96	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HFFBLOFH_01353	9.38e-317	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HFFBLOFH_01354	4.87e-180	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
HFFBLOFH_01355	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HFFBLOFH_01356	7.77e-197	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HFFBLOFH_01357	7.04e-108	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HFFBLOFH_01358	1.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFFBLOFH_01359	3.14e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFFBLOFH_01360	3.39e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HFFBLOFH_01361	2.3e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFFBLOFH_01363	1.28e-54	-	-	-	-	-	-	-	-
HFFBLOFH_01364	2.07e-217	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFFBLOFH_01365	1.05e-234	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HFFBLOFH_01366	1.94e-95	gph1	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant
HFFBLOFH_01367	1.01e-188	-	-	-	-	-	-	-	-
HFFBLOFH_01368	8.84e-18	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HFFBLOFH_01369	2.02e-106	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HFFBLOFH_01370	2.45e-134	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HFFBLOFH_01371	1.48e-27	-	-	-	-	-	-	-	-
HFFBLOFH_01372	7.48e-96	-	-	-	F	-	-	-	Nudix hydrolase
HFFBLOFH_01373	1.23e-189	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HFFBLOFH_01374	6.12e-115	-	-	-	-	-	-	-	-
HFFBLOFH_01375	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HFFBLOFH_01376	3.8e-61	-	-	-	-	-	-	-	-
HFFBLOFH_01377	1.55e-89	-	-	-	O	-	-	-	OsmC-like protein
HFFBLOFH_01378	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HFFBLOFH_01379	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HFFBLOFH_01380	5.01e-229	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HFFBLOFH_01381	3.45e-231	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HFFBLOFH_01382	0.0	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HFFBLOFH_01383	5.47e-198	ribC1	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HFFBLOFH_01384	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HFFBLOFH_01385	1.79e-287	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HFFBLOFH_01386	1.36e-27	-	-	-	-	-	-	-	-
HFFBLOFH_01387	3.68e-107	-	-	-	K	-	-	-	Transcriptional regulator
HFFBLOFH_01388	7.8e-196	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HFFBLOFH_01389	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HFFBLOFH_01390	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HFFBLOFH_01391	4.45e-226	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HFFBLOFH_01392	3.49e-315	-	-	-	EGP	-	-	-	Major Facilitator
HFFBLOFH_01393	1.71e-116	-	-	-	V	-	-	-	VanZ like family
HFFBLOFH_01394	3.88e-46	-	-	-	-	-	-	-	-
HFFBLOFH_01395	5.45e-94	spx1	-	-	P	ko:K16509	-	ko00000	ArsC family
HFFBLOFH_01397	6.37e-186	-	-	-	-	-	-	-	-
HFFBLOFH_01398	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HFFBLOFH_01399	7.08e-197	-	-	-	G	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HFFBLOFH_01400	2.87e-168	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HFFBLOFH_01401	2.49e-95	-	-	-	-	-	-	-	-
HFFBLOFH_01402	3.38e-70	-	-	-	-	-	-	-	-
HFFBLOFH_01403	1.46e-263	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HFFBLOFH_01404	1.21e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFFBLOFH_01405	8.04e-190	-	3.1.3.23	-	S	ko:K07757	-	ko00000,ko01000	Sucrose-6F-phosphate phosphohydrolase
HFFBLOFH_01406	5.44e-159	-	-	-	T	-	-	-	EAL domain
HFFBLOFH_01417	3.26e-119	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
HFFBLOFH_01418	6.36e-237	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
HFFBLOFH_01419	1.25e-124	-	-	-	-	-	-	-	-
HFFBLOFH_01420	1.58e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HFFBLOFH_01421	2.98e-46	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HFFBLOFH_01422	3.47e-134	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HFFBLOFH_01424	2.19e-291	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HFFBLOFH_01425	6.21e-241	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HFFBLOFH_01426	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HFFBLOFH_01427	2.75e-216	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HFFBLOFH_01428	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HFFBLOFH_01429	3.35e-157	-	-	-	-	-	-	-	-
HFFBLOFH_01430	2.78e-273	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HFFBLOFH_01431	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
HFFBLOFH_01432	1.37e-60	-	-	-	N	-	-	-	Cell shape-determining protein MreB
HFFBLOFH_01433	1.21e-185	-	-	-	N	-	-	-	Cell shape-determining protein MreB
HFFBLOFH_01434	0.0	-	-	-	S	-	-	-	Pfam Methyltransferase
HFFBLOFH_01435	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HFFBLOFH_01436	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HFFBLOFH_01437	9.32e-40	-	-	-	-	-	-	-	-
HFFBLOFH_01438	3.03e-122	mraW1	-	-	J	-	-	-	Putative rRNA methylase
HFFBLOFH_01439	3.58e-161	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HFFBLOFH_01440	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HFFBLOFH_01441	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HFFBLOFH_01442	5.04e-176	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HFFBLOFH_01443	3.03e-193	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HFFBLOFH_01444	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HFFBLOFH_01445	2.16e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HFFBLOFH_01446	2.92e-258	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
HFFBLOFH_01447	1.13e-221	ugpA	-	-	U	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HFFBLOFH_01448	3.05e-193	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFFBLOFH_01449	5.01e-229	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HFFBLOFH_01450	2.07e-155	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HFFBLOFH_01451	3.55e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HFFBLOFH_01452	3e-315	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
HFFBLOFH_01454	3.34e-160	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HFFBLOFH_01455	3.06e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HFFBLOFH_01456	2.57e-226	-	-	-	K	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
HFFBLOFH_01458	6.96e-198	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HFFBLOFH_01459	5.2e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HFFBLOFH_01460	1.64e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
HFFBLOFH_01461	9.36e-205	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HFFBLOFH_01462	1.89e-189	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HFFBLOFH_01463	7.83e-140	-	-	-	-	-	-	-	-
HFFBLOFH_01464	2.08e-283	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HFFBLOFH_01465	9.01e-179	agrA	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HFFBLOFH_01466	5.37e-74	-	-	-	-	-	-	-	-
HFFBLOFH_01467	4.56e-78	-	-	-	-	-	-	-	-
HFFBLOFH_01468	1.23e-145	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HFFBLOFH_01469	2.2e-111	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HFFBLOFH_01470	8.82e-119	-	-	-	-	-	-	-	-
HFFBLOFH_01471	7.12e-62	-	-	-	-	-	-	-	-
HFFBLOFH_01472	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
HFFBLOFH_01475	4.29e-87	-	-	-	-	-	-	-	-
HFFBLOFH_01476	9.03e-16	-	-	-	-	-	-	-	-
HFFBLOFH_01477	3.89e-237	-	-	-	-	-	-	-	-
HFFBLOFH_01478	4.91e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
HFFBLOFH_01479	8.01e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
HFFBLOFH_01480	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HFFBLOFH_01481	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HFFBLOFH_01482	0.0	-	-	-	S	-	-	-	Protein conserved in bacteria
HFFBLOFH_01483	7.32e-292	sat	2.7.7.4	-	H	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HFFBLOFH_01484	3.72e-145	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HFFBLOFH_01485	2.54e-225	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
HFFBLOFH_01486	0.0	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
HFFBLOFH_01487	0.0	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HFFBLOFH_01488	4.75e-157	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HFFBLOFH_01489	1.13e-171	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HFFBLOFH_01490	4.87e-156	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HFFBLOFH_01491	4.32e-294	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HFFBLOFH_01492	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HFFBLOFH_01493	1.96e-137	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HFFBLOFH_01494	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HFFBLOFH_01495	1.17e-135	-	-	-	K	-	-	-	transcriptional regulator
HFFBLOFH_01496	2.04e-158	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HFFBLOFH_01497	1.49e-63	-	-	-	-	-	-	-	-
HFFBLOFH_01498	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HFFBLOFH_01499	5.06e-236	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HFFBLOFH_01500	2.87e-56	-	-	-	-	-	-	-	-
HFFBLOFH_01501	1.6e-73	-	-	-	-	-	-	-	-
HFFBLOFH_01502	6.86e-311	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFFBLOFH_01503	2.78e-167	yidA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HFFBLOFH_01504	9.86e-65	-	-	-	-	-	-	-	-
HFFBLOFH_01505	2.58e-163	rrp2	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HFFBLOFH_01506	1.72e-315	hpk2	-	-	T	-	-	-	Histidine kinase
HFFBLOFH_01507	2.2e-86	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HFFBLOFH_01508	0.0	ydiC	-	-	EGP	-	-	-	Major Facilitator
HFFBLOFH_01509	3.13e-55	-	-	-	-	-	-	-	-
HFFBLOFH_01510	6.37e-52	-	-	-	-	-	-	-	-
HFFBLOFH_01511	4.5e-150	-	-	-	-	-	-	-	-
HFFBLOFH_01512	4.02e-301	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HFFBLOFH_01513	8.62e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFFBLOFH_01514	8.9e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
HFFBLOFH_01515	2.73e-92	-	-	-	-	-	-	-	-
HFFBLOFH_01516	3.37e-129	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HFFBLOFH_01517	0.0	tagF2	2.7.8.12	-	H	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HFFBLOFH_01518	5.71e-306	tagB	2.7.8.12, 2.7.8.45	-	M	ko:K09809,ko:K21591	-	ko00000,ko01000	glycerophosphotransferase
HFFBLOFH_01519	1.21e-94	tagD	2.7.7.15, 2.7.7.39	-	IM	ko:K00968,ko:K00980	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Glycerol-3-phosphate cytidylyltransferase
HFFBLOFH_01520	2.6e-185	-	-	-	-	-	-	-	-
HFFBLOFH_01521	0.0	pts5ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HFFBLOFH_01522	0.0	pts4ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFFBLOFH_01523	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HFFBLOFH_01524	1.68e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HFFBLOFH_01525	6.35e-56	-	-	-	-	-	-	-	-
HFFBLOFH_01526	7.55e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
HFFBLOFH_01527	1.27e-181	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HFFBLOFH_01528	6.72e-203	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HFFBLOFH_01529	2.52e-209	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HFFBLOFH_01530	7.87e-266	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HFFBLOFH_01531	2.13e-124	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
HFFBLOFH_01532	1.82e-126	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
HFFBLOFH_01533	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HFFBLOFH_01534	2.41e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HFFBLOFH_01535	1.73e-89	-	-	-	-	-	-	-	-
HFFBLOFH_01536	2.37e-123	-	-	-	-	-	-	-	-
HFFBLOFH_01537	5.92e-67	-	-	-	-	-	-	-	-
HFFBLOFH_01538	4.81e-76	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HFFBLOFH_01539	1.21e-111	-	-	-	-	-	-	-	-
HFFBLOFH_01540	1.76e-280	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HFFBLOFH_01541	5.33e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFFBLOFH_01542	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
HFFBLOFH_01543	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HFFBLOFH_01544	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HFFBLOFH_01545	7.02e-126	-	-	-	K	-	-	-	Helix-turn-helix domain
HFFBLOFH_01546	3.91e-283	-	-	-	C	-	-	-	FAD dependent oxidoreductase
HFFBLOFH_01547	1.82e-220	-	-	-	P	-	-	-	Major Facilitator Superfamily
HFFBLOFH_01548	3.16e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HFFBLOFH_01549	2.32e-43	ygzD	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
HFFBLOFH_01550	1.2e-91	-	-	-	-	-	-	-	-
HFFBLOFH_01551	1.05e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HFFBLOFH_01552	5.3e-202	dkgB	-	-	S	-	-	-	reductase
HFFBLOFH_01553	6.07e-117	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HFFBLOFH_01554	2.02e-131	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC transporter permease
HFFBLOFH_01555	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HFFBLOFH_01556	1.5e-150	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HFFBLOFH_01557	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HFFBLOFH_01558	2.1e-33	-	-	-	-	-	-	-	-
HFFBLOFH_01559	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFFBLOFH_01560	1.89e-254	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HFFBLOFH_01561	2.62e-76	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HFFBLOFH_01562	0.0	-	3.6.3.44	-	P	ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
HFFBLOFH_01563	4.63e-24	-	-	-	-	-	-	-	-
HFFBLOFH_01564	2.69e-23	-	-	-	-	-	-	-	-
HFFBLOFH_01565	9.05e-22	-	-	-	-	-	-	-	-
HFFBLOFH_01566	2.55e-217	inlJ	-	-	M	-	-	-	MucBP domain
HFFBLOFH_01567	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
HFFBLOFH_01568	1.27e-109	-	-	-	K	-	-	-	MarR family
HFFBLOFH_01569	9.28e-58	-	-	-	-	-	-	-	-
HFFBLOFH_01570	1.28e-51	-	-	-	-	-	-	-	-
HFFBLOFH_01571	1.79e-289	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HFFBLOFH_01572	1.1e-06	-	-	-	K	ko:K07727	-	ko00000,ko03000	transcriptional regulator
HFFBLOFH_01575	2.62e-40	-	-	-	-	-	-	-	-
HFFBLOFH_01576	1.5e-187	-	-	-	L	-	-	-	DNA replication protein
HFFBLOFH_01577	0.0	-	-	-	S	-	-	-	Virulence-associated protein E
HFFBLOFH_01578	3.36e-96	-	-	-	-	-	-	-	-
HFFBLOFH_01580	3.24e-62	-	-	-	S	-	-	-	Head-tail joining protein
HFFBLOFH_01581	1.05e-88	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	Phage-associated protein
HFFBLOFH_01582	1.9e-109	terS	-	-	L	-	-	-	Phage terminase, small subunit
HFFBLOFH_01583	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
HFFBLOFH_01585	6.16e-260	-	-	-	S	-	-	-	Phage portal protein
HFFBLOFH_01586	0.0	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
HFFBLOFH_01587	1.75e-48	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HFFBLOFH_01588	1.02e-80	-	-	-	-	-	-	-	-
HFFBLOFH_01590	1.98e-40	-	-	-	-	-	-	-	-
HFFBLOFH_01592	9.38e-279	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HFFBLOFH_01596	4.23e-19	-	-	-	S	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HFFBLOFH_01598	2.69e-38	-	-	-	S	-	-	-	TerB N-terminal domain
HFFBLOFH_01599	1.92e-97	-	-	-	E	-	-	-	IrrE N-terminal-like domain
HFFBLOFH_01600	2.67e-80	-	-	-	K	-	-	-	Helix-turn-helix domain
HFFBLOFH_01601	7.19e-51	-	-	-	K	-	-	-	Helix-turn-helix
HFFBLOFH_01603	6.59e-72	-	-	-	-	-	-	-	-
HFFBLOFH_01604	2.15e-110	-	-	-	-	-	-	-	-
HFFBLOFH_01606	8e-70	-	-	-	S	-	-	-	Bacteriophage Mu Gam like protein
HFFBLOFH_01607	6.45e-80	-	-	-	-	-	-	-	-
HFFBLOFH_01608	7.28e-213	-	-	-	L	-	-	-	DnaD domain protein
HFFBLOFH_01609	3.24e-67	-	-	-	-	-	-	-	-
HFFBLOFH_01610	9.03e-83	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HFFBLOFH_01612	3.54e-18	-	-	-	S	-	-	-	YopX protein
HFFBLOFH_01617	2.49e-97	-	-	-	K	-	-	-	acetyltransferase
HFFBLOFH_01618	1.15e-40	-	-	-	S	-	-	-	ASCH
HFFBLOFH_01619	7.56e-25	-	-	-	-	-	-	-	-
HFFBLOFH_01622	3.13e-98	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
HFFBLOFH_01624	2.91e-316	-	-	-	S	ko:K06909	-	ko00000	Phage terminase, large subunit
HFFBLOFH_01625	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HFFBLOFH_01626	5.76e-216	-	-	-	S	-	-	-	Phage Mu protein F like protein
HFFBLOFH_01627	2.66e-110	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
HFFBLOFH_01628	2.45e-247	gpG	-	-	-	-	-	-	-
HFFBLOFH_01629	3.11e-75	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HFFBLOFH_01630	5.46e-67	-	-	-	-	-	-	-	-
HFFBLOFH_01631	9.66e-123	-	-	-	-	-	-	-	-
HFFBLOFH_01632	5.59e-81	-	-	-	-	-	-	-	-
HFFBLOFH_01633	2.09e-123	-	-	-	-	-	-	-	-
HFFBLOFH_01634	5.37e-107	-	-	-	S	-	-	-	Phage tail assembly chaperone protein, TAC
HFFBLOFH_01636	0.0	-	-	-	D	-	-	-	domain protein
HFFBLOFH_01637	9.72e-173	-	-	-	S	-	-	-	phage tail
HFFBLOFH_01638	0.0	-	-	-	M	-	-	-	Prophage endopeptidase tail
HFFBLOFH_01639	2.64e-220	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HFFBLOFH_01640	8.28e-127	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
HFFBLOFH_01644	1.4e-108	-	-	-	-	-	-	-	-
HFFBLOFH_01645	1.4e-27	-	-	-	-	-	-	-	-
HFFBLOFH_01647	1.41e-214	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HFFBLOFH_01648	9.01e-215	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HFFBLOFH_01649	7.76e-181	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HFFBLOFH_01650	2.38e-99	-	-	-	-	-	-	-	-
HFFBLOFH_01651	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HFFBLOFH_01652	2.4e-180	-	-	-	-	-	-	-	-
HFFBLOFH_01653	4.07e-05	-	-	-	-	-	-	-	-
HFFBLOFH_01654	5.66e-184	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HFFBLOFH_01655	1.67e-54	-	-	-	-	-	-	-	-
HFFBLOFH_01656	4.29e-166	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFFBLOFH_01657	9.79e-192	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HFFBLOFH_01658	1.84e-235	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
HFFBLOFH_01659	1.15e-155	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
HFFBLOFH_01660	7.9e-306	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
HFFBLOFH_01661	1.78e-160	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
HFFBLOFH_01662	3.58e-174	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HFFBLOFH_01663	1.19e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HFFBLOFH_01664	2.6e-193	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
HFFBLOFH_01665	7.11e-227	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HFFBLOFH_01666	1.87e-175	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HFFBLOFH_01667	7.44e-192	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HFFBLOFH_01668	1.61e-144	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HFFBLOFH_01669	1.45e-261	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HFFBLOFH_01670	2.39e-174	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HFFBLOFH_01671	0.0	-	-	-	L	-	-	-	HIRAN domain
HFFBLOFH_01672	1.24e-109	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HFFBLOFH_01673	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HFFBLOFH_01674	5.18e-159	-	-	-	-	-	-	-	-
HFFBLOFH_01675	2.07e-191	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HFFBLOFH_01676	0.0	pacL1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HFFBLOFH_01677	1.34e-183	-	-	-	F	-	-	-	Phosphorylase superfamily
HFFBLOFH_01678	2.92e-38	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HFFBLOFH_01679	1.72e-142	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HFFBLOFH_01680	1.27e-98	-	-	-	K	-	-	-	Transcriptional regulator
HFFBLOFH_01681	3.99e-96	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HFFBLOFH_01682	5.51e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HFFBLOFH_01683	5.38e-290	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HFFBLOFH_01684	3.98e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HFFBLOFH_01685	2.79e-274	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HFFBLOFH_01687	2.16e-204	morA	-	-	S	-	-	-	reductase
HFFBLOFH_01688	8.21e-213	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo keto reductase
HFFBLOFH_01689	1.92e-106	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase like
HFFBLOFH_01690	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HFFBLOFH_01691	7.45e-103	-	-	-	-	-	-	-	-
HFFBLOFH_01692	0.0	-	-	-	-	-	-	-	-
HFFBLOFH_01693	6.49e-268	-	-	-	C	-	-	-	Oxidoreductase
HFFBLOFH_01694	3.28e-193	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HFFBLOFH_01695	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFFBLOFH_01696	2.57e-128	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HFFBLOFH_01698	4.37e-167	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HFFBLOFH_01699	4.14e-72	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HFFBLOFH_01700	2.09e-171	-	-	-	-	-	-	-	-
HFFBLOFH_01701	1.57e-191	-	-	-	-	-	-	-	-
HFFBLOFH_01702	3.37e-115	-	-	-	-	-	-	-	-
HFFBLOFH_01703	1.01e-184	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HFFBLOFH_01704	6.03e-218	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HFFBLOFH_01705	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
HFFBLOFH_01706	8.03e-151	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HFFBLOFH_01707	0.0	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
HFFBLOFH_01708	9.67e-98	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HFFBLOFH_01710	5.29e-121	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFFBLOFH_01711	2.35e-243	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
HFFBLOFH_01712	3.05e-236	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
HFFBLOFH_01713	7.88e-131	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
HFFBLOFH_01714	6.76e-75	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
HFFBLOFH_01715	2.32e-171	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HFFBLOFH_01716	2.65e-245	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HFFBLOFH_01717	1.83e-231	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HFFBLOFH_01718	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HFFBLOFH_01719	4.15e-191	yxeH	-	-	S	-	-	-	hydrolase
HFFBLOFH_01720	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HFFBLOFH_01721	1.14e-202	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
HFFBLOFH_01722	2.87e-101	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HFFBLOFH_01723	2.96e-89	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HFFBLOFH_01724	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HFFBLOFH_01725	5.84e-312	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HFFBLOFH_01726	2.28e-290	sdaC	-	-	E	ko:K03837	-	ko00000,ko02000	amino acid
HFFBLOFH_01727	7.51e-159	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HFFBLOFH_01728	2.81e-202	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HFFBLOFH_01729	6.59e-170	-	-	-	S	-	-	-	YheO-like PAS domain
HFFBLOFH_01730	4.01e-36	-	-	-	-	-	-	-	-
HFFBLOFH_01731	2.08e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HFFBLOFH_01732	1.26e-305	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HFFBLOFH_01733	1.91e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HFFBLOFH_01734	2.57e-274	-	-	-	J	-	-	-	translation release factor activity
HFFBLOFH_01735	3.14e-164	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HFFBLOFH_01736	5.35e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HFFBLOFH_01737	1.6e-194	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HFFBLOFH_01738	1.84e-189	-	-	-	-	-	-	-	-
HFFBLOFH_01739	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HFFBLOFH_01740	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HFFBLOFH_01741	9.32e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HFFBLOFH_01742	4.79e-273	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HFFBLOFH_01743	2.58e-85	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HFFBLOFH_01744	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HFFBLOFH_01745	1.37e-248	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	ABC transporter, substratebinding protein
HFFBLOFH_01746	3.03e-202	-	-	-	U	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HFFBLOFH_01747	5.79e-171	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HFFBLOFH_01748	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HFFBLOFH_01749	7.48e-260	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HFFBLOFH_01750	8.87e-245	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HFFBLOFH_01751	2.29e-292	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HFFBLOFH_01752	2.36e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HFFBLOFH_01753	3.52e-273	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
HFFBLOFH_01754	1.52e-240	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HFFBLOFH_01755	1.3e-110	queT	-	-	S	-	-	-	QueT transporter
HFFBLOFH_01756	1.4e-147	-	-	-	S	-	-	-	(CBS) domain
HFFBLOFH_01757	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HFFBLOFH_01758	2.79e-226	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HFFBLOFH_01759	1.43e-129	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HFFBLOFH_01760	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HFFBLOFH_01761	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HFFBLOFH_01762	7.72e-57	yabO	-	-	J	-	-	-	S4 domain protein
HFFBLOFH_01764	2.02e-83	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HFFBLOFH_01765	1.07e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HFFBLOFH_01766	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HFFBLOFH_01767	4.3e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HFFBLOFH_01768	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HFFBLOFH_01769	1.93e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HFFBLOFH_01770	5.33e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HFFBLOFH_01771	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HFFBLOFH_01772	0.0	-	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
HFFBLOFH_01773	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HFFBLOFH_01775	9.45e-160	-	-	-	S	-	-	-	YjbR
HFFBLOFH_01776	4.04e-37	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HFFBLOFH_01777	3.23e-215	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HFFBLOFH_01778	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HFFBLOFH_01779	1.44e-255	glmS2	-	-	M	-	-	-	SIS domain
HFFBLOFH_01780	2.07e-35	-	-	-	S	-	-	-	Belongs to the LOG family
HFFBLOFH_01781	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HFFBLOFH_01782	3.98e-315	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HFFBLOFH_01783	5.85e-92	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HFFBLOFH_01784	5.38e-92	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HFFBLOFH_01785	4.75e-112	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
HFFBLOFH_01786	1.07e-206	-	-	-	GM	-	-	-	NmrA-like family
HFFBLOFH_01787	2.14e-86	-	-	-	K	ko:K22296	-	ko00000,ko03000	Winged helix DNA-binding domain
HFFBLOFH_01788	9.97e-94	spxA	-	-	P	ko:K16509	-	ko00000	ArsC family
HFFBLOFH_01789	3.46e-87	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HFFBLOFH_01790	1.7e-70	-	-	-	-	-	-	-	-
HFFBLOFH_01791	4.98e-275	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
HFFBLOFH_01792	2.11e-82	-	-	-	-	-	-	-	-
HFFBLOFH_01793	1.36e-112	-	-	-	-	-	-	-	-
HFFBLOFH_01794	4.58e-103	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HFFBLOFH_01795	3.78e-73	-	-	-	-	-	-	-	-
HFFBLOFH_01796	4.79e-21	-	-	-	-	-	-	-	-
HFFBLOFH_01797	3.57e-150	-	-	-	GM	-	-	-	NmrA-like family
HFFBLOFH_01798	2.52e-107	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HFFBLOFH_01799	9.43e-203	-	-	-	EG	-	-	-	EamA-like transporter family
HFFBLOFH_01800	2.66e-155	-	-	-	S	-	-	-	membrane
HFFBLOFH_01801	1.47e-144	-	-	-	S	-	-	-	VIT family
HFFBLOFH_01802	4.38e-243	pva2	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HFFBLOFH_01803	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HFFBLOFH_01804	8.01e-97	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HFFBLOFH_01805	4.26e-54	-	-	-	-	-	-	-	-
HFFBLOFH_01806	3.43e-96	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
HFFBLOFH_01807	8.8e-315	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HFFBLOFH_01808	7.21e-35	-	-	-	-	-	-	-	-
HFFBLOFH_01809	2.55e-65	-	-	-	-	-	-	-	-
HFFBLOFH_01810	2.51e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF1398)
HFFBLOFH_01811	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HFFBLOFH_01812	1.77e-282	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HFFBLOFH_01813	9.92e-230	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HFFBLOFH_01814	6.1e-101	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HFFBLOFH_01815	1.14e-110	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HFFBLOFH_01816	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HFFBLOFH_01817	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HFFBLOFH_01818	2.3e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HFFBLOFH_01819	1.36e-209	yvgN	-	-	C	-	-	-	Aldo keto reductase
HFFBLOFH_01820	2.57e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
HFFBLOFH_01821	1.7e-101	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HFFBLOFH_01822	1.5e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HFFBLOFH_01823	2.69e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HFFBLOFH_01824	5.94e-118	ymdB	-	-	S	-	-	-	Macro domain protein
HFFBLOFH_01825	6.47e-124	-	-	-	K	ko:K22041	-	ko00000,ko03000	transcriptional regulator
HFFBLOFH_01826	1.58e-66	-	-	-	-	-	-	-	-
HFFBLOFH_01827	2.41e-212	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HFFBLOFH_01828	0.0	-	-	-	-	-	-	-	-
HFFBLOFH_01829	2.08e-161	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HFFBLOFH_01830	3.5e-205	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HFFBLOFH_01831	2.97e-244	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HFFBLOFH_01832	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HFFBLOFH_01833	1.55e-230	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HFFBLOFH_01834	5.55e-100	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HFFBLOFH_01835	6.61e-29	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HFFBLOFH_01836	1.11e-33	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HFFBLOFH_01837	3.38e-50	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HFFBLOFH_01838	1.29e-235	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HFFBLOFH_01839	5.91e-297	-	-	-	P	ko:K06610	-	ko00000,ko02000	Major Facilitator Superfamily
HFFBLOFH_01840	0.0	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HFFBLOFH_01841	2.9e-293	-	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
HFFBLOFH_01842	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HFFBLOFH_01843	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HFFBLOFH_01844	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HFFBLOFH_01845	1.95e-140	aqpZ	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HFFBLOFH_01846	3.7e-279	-	-	-	S	-	-	-	associated with various cellular activities
HFFBLOFH_01847	9.34e-317	-	-	-	S	-	-	-	Putative metallopeptidase domain
HFFBLOFH_01848	1.03e-65	-	-	-	-	-	-	-	-
HFFBLOFH_01849	8.19e-134	yezE	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
HFFBLOFH_01850	7.83e-60	-	-	-	-	-	-	-	-
HFFBLOFH_01851	4.23e-129	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HFFBLOFH_01852	8.67e-160	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HFFBLOFH_01853	1.83e-235	-	-	-	S	-	-	-	Cell surface protein
HFFBLOFH_01854	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HFFBLOFH_01855	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HFFBLOFH_01856	1.06e-106	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HFFBLOFH_01857	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HFFBLOFH_01858	1.82e-152	rcfA	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HFFBLOFH_01859	2.98e-44	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
HFFBLOFH_01860	4.27e-126	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HFFBLOFH_01861	1.01e-26	-	-	-	-	-	-	-	-
HFFBLOFH_01862	4.82e-55	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
HFFBLOFH_01863	5.73e-73	trxA3	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
HFFBLOFH_01864	9.44e-183	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HFFBLOFH_01865	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HFFBLOFH_01866	8.06e-232	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HFFBLOFH_01867	1.5e-165	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
HFFBLOFH_01868	4.16e-175	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HFFBLOFH_01869	4.84e-230	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HFFBLOFH_01870	1.12e-134	-	-	-	K	-	-	-	transcriptional regulator
HFFBLOFH_01872	9.39e-84	-	-	-	-	-	-	-	-
HFFBLOFH_01874	5.77e-81	-	-	-	-	-	-	-	-
HFFBLOFH_01875	6.18e-71	-	-	-	-	-	-	-	-
HFFBLOFH_01876	1.88e-96	-	-	-	M	-	-	-	PFAM NLP P60 protein
HFFBLOFH_01877	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
HFFBLOFH_01878	4.45e-38	-	-	-	-	-	-	-	-
HFFBLOFH_01879	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HFFBLOFH_01880	3.81e-150	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFFBLOFH_01881	3.08e-113	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HFFBLOFH_01882	1.63e-176	yesN	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HFFBLOFH_01883	3.17e-170	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HFFBLOFH_01884	1.56e-71	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HFFBLOFH_01885	2.56e-131	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HFFBLOFH_01886	8.07e-163	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HFFBLOFH_01887	6.36e-134	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HFFBLOFH_01888	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HFFBLOFH_01889	1.56e-108	-	-	-	-	-	-	-	-
HFFBLOFH_01890	5.97e-96	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HFFBLOFH_01891	9.2e-243	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HFFBLOFH_01892	7.3e-245	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HFFBLOFH_01893	3.7e-30	-	-	-	-	-	-	-	-
HFFBLOFH_01894	1.38e-131	-	-	-	-	-	-	-	-
HFFBLOFH_01895	3.46e-210	-	-	-	K	-	-	-	LysR substrate binding domain
HFFBLOFH_01896	4.34e-314	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HFFBLOFH_01897	0.0	-	4.1.1.98	-	H	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HFFBLOFH_01898	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HFFBLOFH_01899	1.37e-182	-	-	-	S	-	-	-	zinc-ribbon domain
HFFBLOFH_01901	4.29e-50	-	-	-	-	-	-	-	-
HFFBLOFH_01902	1.4e-137	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HFFBLOFH_01903	1.4e-20	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HFFBLOFH_01904	2.35e-231	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HFFBLOFH_01905	0.0	-	-	-	I	-	-	-	acetylesterase activity
HFFBLOFH_01906	6.08e-78	-	-	-	M	-	-	-	Collagen binding domain
HFFBLOFH_01907	6.92e-206	yicL	-	-	EG	-	-	-	EamA-like transporter family
HFFBLOFH_01908	6.12e-166	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HFFBLOFH_01909	3.39e-225	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
HFFBLOFH_01910	5.93e-144	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HFFBLOFH_01911	5.07e-62	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HFFBLOFH_01912	3.06e-206	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HFFBLOFH_01913	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
HFFBLOFH_01914	9.86e-117	-	-	-	-	-	-	-	-
HFFBLOFH_01915	1.02e-164	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HFFBLOFH_01916	9.21e-234	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HFFBLOFH_01917	7.39e-121	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HFFBLOFH_01918	5.85e-204	ccpB	-	-	K	-	-	-	lacI family
HFFBLOFH_01919	2.21e-154	yceE	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HFFBLOFH_01920	8.08e-154	ydgI3	-	-	C	-	-	-	Nitroreductase family
HFFBLOFH_01921	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HFFBLOFH_01922	4.21e-150	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HFFBLOFH_01923	5.82e-198	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HFFBLOFH_01924	6.97e-216	XK27_00670	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HFFBLOFH_01925	0.0	-	-	-	-	-	-	-	-
HFFBLOFH_01926	4.71e-81	-	-	-	-	-	-	-	-
HFFBLOFH_01927	5.52e-242	-	-	-	S	-	-	-	Cell surface protein
HFFBLOFH_01928	1.27e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HFFBLOFH_01929	5.06e-82	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HFFBLOFH_01930	3.13e-42	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HFFBLOFH_01931	2.78e-158	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFFBLOFH_01932	5.21e-180	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
HFFBLOFH_01933	2.29e-193	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HFFBLOFH_01934	4.54e-191	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HFFBLOFH_01935	1.04e-269	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HFFBLOFH_01937	1.15e-43	-	-	-	-	-	-	-	-
HFFBLOFH_01938	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HFFBLOFH_01939	9.24e-140	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HFFBLOFH_01940	2.35e-106	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFFBLOFH_01941	2.64e-61	-	-	-	-	-	-	-	-
HFFBLOFH_01942	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HFFBLOFH_01943	1.31e-242	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HFFBLOFH_01944	3.45e-209	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HFFBLOFH_01945	6.83e-292	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HFFBLOFH_01946	6.08e-312	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HFFBLOFH_01947	1.53e-213	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HFFBLOFH_01948	9.31e-225	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HFFBLOFH_01949	6.03e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HFFBLOFH_01950	1.32e-178	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFFBLOFH_01951	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HFFBLOFH_01952	9.51e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
HFFBLOFH_01953	1.18e-175	yceF	-	-	P	ko:K05794	-	ko00000	membrane
HFFBLOFH_01954	2.47e-125	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HFFBLOFH_01955	1.9e-258	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HFFBLOFH_01956	1.07e-68	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
HFFBLOFH_01957	6.12e-78	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HFFBLOFH_01958	1.27e-172	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HFFBLOFH_01959	5.62e-165	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HFFBLOFH_01960	2.23e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HFFBLOFH_01961	2.46e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HFFBLOFH_01962	7.8e-299	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HFFBLOFH_01963	1.69e-151	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HFFBLOFH_01964	2.3e-275	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HFFBLOFH_01965	4.54e-208	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
HFFBLOFH_01966	3.72e-283	ysaA	-	-	V	-	-	-	RDD family
HFFBLOFH_01967	7.28e-213	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HFFBLOFH_01968	6.7e-74	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HFFBLOFH_01969	4.73e-118	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
HFFBLOFH_01970	1.01e-189	-	-	-	GM	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFFBLOFH_01971	4.54e-126	-	-	-	J	-	-	-	glyoxalase III activity
HFFBLOFH_01972	1.97e-254	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HFFBLOFH_01973	5.48e-236	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HFFBLOFH_01974	1.45e-46	-	-	-	-	-	-	-	-
HFFBLOFH_01975	1.06e-145	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HFFBLOFH_01976	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HFFBLOFH_01977	6.32e-67	-	-	-	M	-	-	-	domain protein
HFFBLOFH_01978	1.78e-279	-	-	-	M	-	-	-	domain protein
HFFBLOFH_01979	6.05e-98	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HFFBLOFH_01980	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HFFBLOFH_01981	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HFFBLOFH_01982	2.71e-234	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HFFBLOFH_01983	2.14e-183	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HFFBLOFH_01984	4.84e-227	-	-	-	-	-	-	-	-
HFFBLOFH_01985	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HFFBLOFH_01986	7.1e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HFFBLOFH_01987	2.64e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HFFBLOFH_01988	2.15e-209	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
HFFBLOFH_01989	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HFFBLOFH_01990	2.36e-285	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HFFBLOFH_01991	8.65e-228	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HFFBLOFH_01992	1.21e-268	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HFFBLOFH_01993	3.95e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HFFBLOFH_01994	6.45e-111	-	-	-	-	-	-	-	-
HFFBLOFH_01995	4.86e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HFFBLOFH_01996	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HFFBLOFH_01997	3.45e-240	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HFFBLOFH_01998	2.16e-39	-	-	-	-	-	-	-	-
HFFBLOFH_01999	2.62e-168	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HFFBLOFH_02000	5.35e-220	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFFBLOFH_02001	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HFFBLOFH_02002	1.02e-155	-	-	-	S	-	-	-	repeat protein
HFFBLOFH_02003	2.41e-157	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HFFBLOFH_02004	0.0	-	-	-	N	-	-	-	domain, Protein
HFFBLOFH_02005	2.02e-247	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HFFBLOFH_02006	4.17e-153	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
HFFBLOFH_02007	4.64e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HFFBLOFH_02008	9.64e-307	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HFFBLOFH_02009	1.53e-284	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HFFBLOFH_02010	4.94e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HFFBLOFH_02011	8.09e-275	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HFFBLOFH_02012	5.85e-158	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HFFBLOFH_02013	7.74e-47	-	-	-	-	-	-	-	-
HFFBLOFH_02014	3.51e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HFFBLOFH_02015	3.46e-242	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HFFBLOFH_02016	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HFFBLOFH_02017	6.52e-124	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HFFBLOFH_02018	2.06e-187	ylmH	-	-	S	-	-	-	S4 domain protein
HFFBLOFH_02019	6.45e-49	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HFFBLOFH_02020	1.56e-93	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HFFBLOFH_02021	9.39e-295	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HFFBLOFH_02022	3.55e-312	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HFFBLOFH_02023	2.34e-208	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HFFBLOFH_02024	2.04e-252	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HFFBLOFH_02025	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HFFBLOFH_02026	2.81e-231	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HFFBLOFH_02027	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HFFBLOFH_02028	7.01e-76	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HFFBLOFH_02029	1.74e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HFFBLOFH_02030	7.24e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HFFBLOFH_02031	3.22e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
HFFBLOFH_02032	4.1e-223	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HFFBLOFH_02033	4.54e-54	-	-	-	-	-	-	-	-
HFFBLOFH_02035	8.83e-317	-	-	-	EGP	-	-	-	Major Facilitator
HFFBLOFH_02036	5.61e-216	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HFFBLOFH_02037	4.26e-109	cvpA	-	-	S	-	-	-	Colicin V production protein
HFFBLOFH_02038	9.61e-84	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HFFBLOFH_02039	1.59e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HFFBLOFH_02040	1.8e-134	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HFFBLOFH_02041	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HFFBLOFH_02042	2.01e-134	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HFFBLOFH_02043	5.59e-271	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
HFFBLOFH_02044	3.91e-124	tag2	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HFFBLOFH_02045	8.03e-28	-	-	-	-	-	-	-	-
HFFBLOFH_02046	1.3e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HFFBLOFH_02047	7.27e-73	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HFFBLOFH_02048	2.94e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HFFBLOFH_02049	1.97e-60	qacH	-	-	U	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HFFBLOFH_02050	1.63e-77	-	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HFFBLOFH_02051	1.38e-275	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HFFBLOFH_02052	3.1e-228	ydbI	-	-	K	-	-	-	AI-2E family transporter
HFFBLOFH_02053	1.07e-211	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HFFBLOFH_02054	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HFFBLOFH_02056	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
HFFBLOFH_02057	4.62e-107	-	-	-	-	-	-	-	-
HFFBLOFH_02059	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFFBLOFH_02060	1.02e-187	ptp2	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HFFBLOFH_02061	4.17e-235	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HFFBLOFH_02062	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HFFBLOFH_02063	3.66e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HFFBLOFH_02064	2.05e-72	-	-	-	S	-	-	-	Enterocin A Immunity
HFFBLOFH_02065	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HFFBLOFH_02066	1.49e-253	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HFFBLOFH_02067	9.07e-233	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
HFFBLOFH_02068	2.85e-210	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
HFFBLOFH_02069	0.0	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
HFFBLOFH_02070	7.02e-151	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
HFFBLOFH_02071	1.03e-34	-	-	-	-	-	-	-	-
HFFBLOFH_02072	1.56e-185	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HFFBLOFH_02073	2.88e-164	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
HFFBLOFH_02074	4.14e-84	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
HFFBLOFH_02075	2.8e-135	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HFFBLOFH_02076	1.33e-100	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HFFBLOFH_02077	7.47e-77	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HFFBLOFH_02078	6.46e-49	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
HFFBLOFH_02079	1.28e-77	-	-	-	S	-	-	-	Enterocin A Immunity
HFFBLOFH_02080	1.55e-114	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HFFBLOFH_02081	1.16e-135	-	-	-	-	-	-	-	-
HFFBLOFH_02082	8.44e-304	-	-	-	S	-	-	-	module of peptide synthetase
HFFBLOFH_02083	2.95e-100	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HFFBLOFH_02085	1.25e-164	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
HFFBLOFH_02086	0.0	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFFBLOFH_02087	7.54e-200	-	-	-	GM	-	-	-	NmrA-like family
HFFBLOFH_02088	4.08e-101	-	-	-	K	-	-	-	MerR family regulatory protein
HFFBLOFH_02089	2.81e-167	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
HFFBLOFH_02090	2.88e-106	gtcA3	-	-	S	-	-	-	GtrA-like protein
HFFBLOFH_02091	3.35e-157	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HFFBLOFH_02092	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HFFBLOFH_02093	1.18e-94	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
HFFBLOFH_02094	7.03e-62	-	-	-	-	-	-	-	-
HFFBLOFH_02095	1.81e-150	-	-	-	S	-	-	-	SNARE associated Golgi protein
HFFBLOFH_02096	8.58e-65	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HFFBLOFH_02097	7.89e-124	-	-	-	P	-	-	-	Cadmium resistance transporter
HFFBLOFH_02098	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFFBLOFH_02099	3.93e-38	-	-	-	P	-	-	-	Concanavalin A-like lectin/glucanases superfamily
HFFBLOFH_02101	2.03e-84	-	-	-	-	-	-	-	-
HFFBLOFH_02102	1.58e-204	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HFFBLOFH_02103	1.21e-73	-	-	-	-	-	-	-	-
HFFBLOFH_02104	1.24e-194	-	-	-	K	-	-	-	Helix-turn-helix domain
HFFBLOFH_02105	3.91e-100	pts23A	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HFFBLOFH_02106	7.47e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HFFBLOFH_02107	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFFBLOFH_02108	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFFBLOFH_02109	4.32e-235	-	-	-	GM	-	-	-	Male sterility protein
HFFBLOFH_02110	2.1e-99	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HFFBLOFH_02111	4.61e-101	-	-	-	M	-	-	-	LysM domain
HFFBLOFH_02112	7.94e-126	-	-	-	M	-	-	-	Lysin motif
HFFBLOFH_02113	5.71e-138	-	-	-	S	-	-	-	SdpI/YhfL protein family
HFFBLOFH_02114	1.58e-72	nudA	-	-	S	-	-	-	ASCH
HFFBLOFH_02115	5.76e-212	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HFFBLOFH_02116	3.57e-120	-	-	-	-	-	-	-	-
HFFBLOFH_02117	1.92e-155	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
HFFBLOFH_02118	3.55e-281	-	-	-	T	-	-	-	diguanylate cyclase
HFFBLOFH_02119	7.43e-97	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HFFBLOFH_02120	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HFFBLOFH_02121	2.31e-277	-	-	-	-	-	-	-	-
HFFBLOFH_02122	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFFBLOFH_02123	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HFFBLOFH_02125	3.23e-290	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
HFFBLOFH_02126	2.96e-209	yhxD	-	-	IQ	-	-	-	KR domain
HFFBLOFH_02128	1.97e-92	-	-	-	-	-	-	-	-
HFFBLOFH_02129	1.43e-184	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HFFBLOFH_02130	0.0	-	-	-	E	-	-	-	Amino Acid
HFFBLOFH_02131	4.8e-86	lysM	-	-	M	-	-	-	LysM domain
HFFBLOFH_02132	4.2e-286	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HFFBLOFH_02133	6.8e-272	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
HFFBLOFH_02134	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HFFBLOFH_02135	1.23e-57	-	-	-	S	-	-	-	Cupredoxin-like domain
HFFBLOFH_02136	1.36e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
HFFBLOFH_02137	2.69e-316	dinF	-	-	V	-	-	-	MatE
HFFBLOFH_02138	1.79e-42	-	-	-	-	-	-	-	-
HFFBLOFH_02140	8.2e-102	yybD	-	-	S	ko:K02348	-	ko00000	Acetyltransferase (GNAT) domain
HFFBLOFH_02141	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HFFBLOFH_02142	4.64e-106	-	-	-	-	-	-	-	-
HFFBLOFH_02143	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HFFBLOFH_02144	1.04e-136	-	-	-	-	-	-	-	-
HFFBLOFH_02145	0.0	celR	-	-	K	-	-	-	PRD domain
HFFBLOFH_02146	1.34e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HFFBLOFH_02147	2.37e-68	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HFFBLOFH_02148	4.9e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HFFBLOFH_02149	1.71e-277	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFFBLOFH_02150	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFFBLOFH_02151	3.5e-271	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
HFFBLOFH_02152	2.34e-146	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HFFBLOFH_02153	1.65e-46	dltC2	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFFBLOFH_02154	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	Alanine-glyoxylate amino-transferase
HFFBLOFH_02155	8.08e-133	argO	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
HFFBLOFH_02156	5.58e-271	arcT	-	-	E	-	-	-	Aminotransferase
HFFBLOFH_02157	2.07e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HFFBLOFH_02158	2.43e-18	-	-	-	-	-	-	-	-
HFFBLOFH_02159	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HFFBLOFH_02160	9.94e-71	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HFFBLOFH_02161	4.47e-296	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HFFBLOFH_02162	0.0	yhaN	-	-	L	-	-	-	AAA domain
HFFBLOFH_02163	1.03e-240	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HFFBLOFH_02164	1.05e-272	-	-	-	-	-	-	-	-
HFFBLOFH_02165	2.41e-233	-	-	-	M	-	-	-	Peptidase family S41
HFFBLOFH_02166	1.09e-225	-	-	-	K	-	-	-	LysR substrate binding domain
HFFBLOFH_02167	9.9e-144	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HFFBLOFH_02168	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HFFBLOFH_02169	4.43e-129	-	-	-	-	-	-	-	-
HFFBLOFH_02170	1.17e-100	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
HFFBLOFH_02171	1.15e-235	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
HFFBLOFH_02172	7.78e-20	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HFFBLOFH_02173	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HFFBLOFH_02174	4.29e-26	-	-	-	S	-	-	-	NUDIX domain
HFFBLOFH_02175	0.0	-	-	-	S	-	-	-	membrane
HFFBLOFH_02176	4.26e-218	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HFFBLOFH_02177	2.61e-95	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HFFBLOFH_02178	2.08e-284	ribA	3.5.4.25, 4.1.99.12	-	H	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HFFBLOFH_02179	1.23e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HFFBLOFH_02180	5.21e-137	-	-	-	S	ko:K09962	-	ko00000	Nucleotidyltransferase
HFFBLOFH_02181	1.96e-137	-	-	-	-	-	-	-	-
HFFBLOFH_02182	3.3e-151	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HFFBLOFH_02183	1.08e-95	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFFBLOFH_02184	1.75e-47	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HFFBLOFH_02185	2.03e-155	azlC	-	-	E	-	-	-	branched-chain amino acid
HFFBLOFH_02186	3.43e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HFFBLOFH_02187	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HFFBLOFH_02188	9.85e-281	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HFFBLOFH_02189	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HFFBLOFH_02190	0.0	xylP2	-	-	G	-	-	-	symporter
HFFBLOFH_02191	4.24e-246	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HFFBLOFH_02192	3.33e-64	-	-	-	-	-	-	-	-
HFFBLOFH_02193	1.24e-155	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
HFFBLOFH_02194	7.84e-117	-	-	-	K	-	-	-	FR47-like protein
HFFBLOFH_02195	4.18e-163	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HFFBLOFH_02196	1.89e-277	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HFFBLOFH_02197	2.26e-243	-	-	-	-	-	-	-	-
HFFBLOFH_02198	2.91e-179	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HFFBLOFH_02199	5.06e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HFFBLOFH_02200	9.95e-211	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HFFBLOFH_02201	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HFFBLOFH_02202	4.95e-44	-	-	-	L	-	-	-	leucine-zipper of insertion element IS481
HFFBLOFH_02203	9.05e-55	-	-	-	-	-	-	-	-
HFFBLOFH_02204	1.32e-290	-	-	-	L	-	-	-	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HFFBLOFH_02205	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HFFBLOFH_02206	3.39e-255	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HFFBLOFH_02207	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HFFBLOFH_02208	1.64e-149	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HFFBLOFH_02209	4.3e-106	-	-	-	K	-	-	-	Transcriptional regulator
HFFBLOFH_02211	5.68e-266	-	-	-	C	-	-	-	FMN_bind
HFFBLOFH_02212	4.37e-120	-	-	-	C	-	-	-	FMN_bind
HFFBLOFH_02213	3.93e-220	-	-	-	K	-	-	-	Transcriptional regulator
HFFBLOFH_02214	7.39e-54	-	-	-	K	-	-	-	Helix-turn-helix domain
HFFBLOFH_02215	2.56e-60	-	-	-	K	-	-	-	Helix-turn-helix domain
HFFBLOFH_02216	7.45e-180	-	-	-	K	-	-	-	sequence-specific DNA binding
HFFBLOFH_02217	1.73e-113	-	-	-	S	-	-	-	AAA domain
HFFBLOFH_02218	1.42e-08	-	-	-	-	-	-	-	-
HFFBLOFH_02219	5.1e-315	-	-	-	M	-	-	-	MucBP domain
HFFBLOFH_02220	0.0	-	-	-	M	-	-	-	MucBP domain
HFFBLOFH_02221	4.85e-119	XK27_09665	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
HFFBLOFH_02222	3.79e-57	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HFFBLOFH_02223	4.61e-222	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HFFBLOFH_02224	5.09e-81	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
HFFBLOFH_02225	9.16e-190	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HFFBLOFH_02226	2.92e-118	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HFFBLOFH_02227	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HFFBLOFH_02228	3.73e-131	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HFFBLOFH_02229	2.33e-283	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HFFBLOFH_02230	1.07e-131	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HFFBLOFH_02231	1.8e-249	-	-	-	C	-	-	-	Aldo/keto reductase family
HFFBLOFH_02233	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFFBLOFH_02234	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFFBLOFH_02235	6.27e-316	-	-	-	EGP	-	-	-	Major Facilitator
HFFBLOFH_02240	2.06e-313	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HFFBLOFH_02241	1.23e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
HFFBLOFH_02242	6.88e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HFFBLOFH_02243	4.36e-197	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HFFBLOFH_02244	1.39e-134	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HFFBLOFH_02245	8.76e-126	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HFFBLOFH_02246	2.09e-287	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HFFBLOFH_02247	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HFFBLOFH_02248	5.69e-191	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HFFBLOFH_02249	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HFFBLOFH_02250	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
HFFBLOFH_02251	1.35e-264	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HFFBLOFH_02252	1.54e-219	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HFFBLOFH_02253	1.76e-298	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HFFBLOFH_02254	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HFFBLOFH_02255	9.55e-205	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HFFBLOFH_02256	1.01e-167	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HFFBLOFH_02257	0.0	-	-	-	-	-	-	-	-
HFFBLOFH_02258	2e-52	-	-	-	S	-	-	-	Cytochrome B5
HFFBLOFH_02259	8.68e-118	pts21A	-	-	G	ko:K02755	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HFFBLOFH_02260	6.48e-135	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HFFBLOFH_02261	6.39e-169	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HFFBLOFH_02262	8.05e-166	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HFFBLOFH_02263	1.9e-230	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
HFFBLOFH_02264	2.26e-209	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HFFBLOFH_02265	6.87e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HFFBLOFH_02266	1.19e-201	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HFFBLOFH_02267	1.6e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HFFBLOFH_02268	1.63e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HFFBLOFH_02270	2.53e-106	mutR	-	-	K	ko:K20373,ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
HFFBLOFH_02271	1.81e-273	-	-	-	EGP	ko:K02030	-	ko00000,ko00002,ko02000	Drug resistance transporter Bcr CflA subfamily
HFFBLOFH_02272	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HFFBLOFH_02273	4.64e-92	-	-	-	F	-	-	-	DNA mismatch repair protein MutT
HFFBLOFH_02274	1.12e-205	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HFFBLOFH_02275	3.56e-170	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HFFBLOFH_02276	7.71e-228	-	-	-	-	-	-	-	-
HFFBLOFH_02277	1.37e-290	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HFFBLOFH_02278	1.36e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HFFBLOFH_02279	4.87e-243	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HFFBLOFH_02280	1.6e-77	chpA	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HFFBLOFH_02281	5.9e-46	-	-	-	-	-	-	-	-
HFFBLOFH_02282	1.69e-97	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HFFBLOFH_02283	9.68e-34	-	-	-	-	-	-	-	-
HFFBLOFH_02284	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFFBLOFH_02285	2.69e-166	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HFFBLOFH_02286	2.35e-243	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HFFBLOFH_02287	1.38e-179	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HFFBLOFH_02288	0.0	-	-	-	L	-	-	-	DNA helicase
HFFBLOFH_02289	4.23e-64	axe	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
HFFBLOFH_02290	3.74e-144	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HFFBLOFH_02291	4.56e-144	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HFFBLOFH_02292	8.02e-152	plnU	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HFFBLOFH_02293	2.6e-140	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HFFBLOFH_02294	1.17e-306	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
HFFBLOFH_02295	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HFFBLOFH_02296	2.59e-19	-	-	-	-	-	-	-	-
HFFBLOFH_02297	1.93e-31	plnF	-	-	-	-	-	-	-
HFFBLOFH_02298	8.15e-167	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HFFBLOFH_02299	4.32e-261	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HFFBLOFH_02300	7.22e-163	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HFFBLOFH_02301	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HFFBLOFH_02302	4.03e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HFFBLOFH_02303	8.99e-133	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HFFBLOFH_02304	2.17e-222	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HFFBLOFH_02305	5.9e-194	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HFFBLOFH_02306	0.0	tagE5	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
HFFBLOFH_02307	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HFFBLOFH_02309	2.24e-78	-	-	-	M	-	-	-	LysM domain
HFFBLOFH_02310	6.5e-119	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
HFFBLOFH_02311	1.65e-212	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFFBLOFH_02312	3.91e-269	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HFFBLOFH_02313	6.27e-166	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFFBLOFH_02314	4.72e-72	cmd	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HFFBLOFH_02315	4.77e-100	yphH	-	-	S	-	-	-	Cupin domain
HFFBLOFH_02316	5.19e-103	-	-	-	K	-	-	-	transcriptional regulator, MerR family
HFFBLOFH_02317	4.87e-298	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HFFBLOFH_02318	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HFFBLOFH_02319	1.74e-156	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFFBLOFH_02321	1.19e-150	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HFFBLOFH_02322	3.18e-141	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HFFBLOFH_02323	1.03e-150	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HFFBLOFH_02325	4.86e-111	-	-	-	-	-	-	-	-
HFFBLOFH_02326	1.04e-110	yvbK	-	-	K	-	-	-	GNAT family
HFFBLOFH_02327	9.76e-50	-	-	-	-	-	-	-	-
HFFBLOFH_02328	2.81e-64	-	-	-	-	-	-	-	-
HFFBLOFH_02329	7.44e-143	pgm8	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
HFFBLOFH_02330	6.09e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
HFFBLOFH_02331	1.51e-200	-	-	-	K	-	-	-	LysR substrate binding domain
HFFBLOFH_02332	1.52e-135	-	-	-	GM	-	-	-	NAD(P)H-binding
HFFBLOFH_02333	1.66e-247	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HFFBLOFH_02334	2.9e-194	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HFFBLOFH_02335	1.28e-45	-	-	-	-	-	-	-	-
HFFBLOFH_02336	2.1e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HFFBLOFH_02337	2.09e-124	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HFFBLOFH_02338	1.76e-162	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HFFBLOFH_02339	1.03e-40	-	-	-	-	-	-	-	-
HFFBLOFH_02340	1.17e-60	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HFFBLOFH_02341	6.27e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HFFBLOFH_02342	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HFFBLOFH_02343	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFFBLOFH_02344	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HFFBLOFH_02345	3.97e-229	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HFFBLOFH_02346	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HFFBLOFH_02347	4.71e-210	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HFFBLOFH_02348	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HFFBLOFH_02349	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HFFBLOFH_02350	1.63e-163	mleR	-	-	K	-	-	-	LysR substrate binding domain
HFFBLOFH_02351	5.44e-35	mleR	-	-	K	-	-	-	LysR substrate binding domain
HFFBLOFH_02352	0.0	-	-	-	M	-	-	-	domain protein
HFFBLOFH_02354	1.03e-201	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HFFBLOFH_02355	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFFBLOFH_02356	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFFBLOFH_02357	2.65e-102	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HFFBLOFH_02358	1.45e-278	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFFBLOFH_02359	1.24e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HFFBLOFH_02360	6.7e-148	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
HFFBLOFH_02361	3.38e-227	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HFFBLOFH_02362	6.33e-46	-	-	-	-	-	-	-	-
HFFBLOFH_02363	1.15e-79	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HFFBLOFH_02364	4.37e-208	fbpA	-	-	K	-	-	-	Domain of unknown function (DUF814)
HFFBLOFH_02365	1.29e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFFBLOFH_02366	3.81e-18	-	-	-	-	-	-	-	-
HFFBLOFH_02367	3.18e-77	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFFBLOFH_02368	5.66e-74	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFFBLOFH_02369	2.2e-280	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
HFFBLOFH_02370	1.5e-104	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFFBLOFH_02371	5.55e-22	-	-	-	G	ko:K11203	-	ko00000,ko00002,ko02000	PTS system, fructose subfamily
HFFBLOFH_02372	2.52e-35	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HFFBLOFH_02373	9.49e-155	fptC	-	-	U	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase system, EIIC
HFFBLOFH_02374	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
HFFBLOFH_02375	2.24e-116	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HFFBLOFH_02376	3.54e-190	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HFFBLOFH_02377	2.69e-194	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
HFFBLOFH_02378	6.26e-101	-	-	-	-	-	-	-	-
HFFBLOFH_02379	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFFBLOFH_02380	2.93e-151	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFFBLOFH_02381	2.44e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HFFBLOFH_02382	3.73e-263	-	-	-	S	-	-	-	DUF218 domain
HFFBLOFH_02383	1.06e-232	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HFFBLOFH_02384	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HFFBLOFH_02385	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFFBLOFH_02386	1.6e-200	-	-	-	S	-	-	-	Putative adhesin
HFFBLOFH_02387	1.73e-132	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HFFBLOFH_02388	2.86e-68	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
HFFBLOFH_02389	1.07e-127	-	-	-	KT	-	-	-	response to antibiotic
HFFBLOFH_02390	1.26e-161	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HFFBLOFH_02391	3.02e-176	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFFBLOFH_02392	2.11e-158	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFFBLOFH_02393	2.13e-167	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HFFBLOFH_02394	2.07e-302	-	-	-	EK	-	-	-	Aminotransferase, class I
HFFBLOFH_02395	3.36e-216	-	-	-	K	-	-	-	LysR substrate binding domain
HFFBLOFH_02396	3.66e-189	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HFFBLOFH_02397	2.89e-312	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HFFBLOFH_02398	2.1e-116	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HFFBLOFH_02399	1.06e-16	-	-	-	-	-	-	-	-
HFFBLOFH_02400	1.96e-21	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
HFFBLOFH_02401	0.0	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
HFFBLOFH_02402	1.32e-101	nrp	-	-	K	ko:K16509	-	ko00000	ArsC family
HFFBLOFH_02403	7.42e-174	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HFFBLOFH_02404	3.78e-212	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HFFBLOFH_02405	9.62e-19	-	-	-	-	-	-	-	-
HFFBLOFH_02406	1.51e-85	-	-	-	KOT	ko:K07813	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01002	May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
HFFBLOFH_02407	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
HFFBLOFH_02409	8.76e-72	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HFFBLOFH_02410	6.67e-165	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HFFBLOFH_02411	0.0	pox4	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HFFBLOFH_02412	5.03e-95	-	-	-	K	-	-	-	Transcriptional regulator
HFFBLOFH_02413	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HFFBLOFH_02414	6.96e-83	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HFFBLOFH_02415	5.88e-233	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
HFFBLOFH_02416	1.23e-129	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
HFFBLOFH_02417	3.33e-113	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
HFFBLOFH_02418	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HFFBLOFH_02419	1.56e-185	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
HFFBLOFH_02420	2.53e-209	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
HFFBLOFH_02421	2.03e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HFFBLOFH_02422	4.52e-209	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HFFBLOFH_02423	1.88e-240	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HFFBLOFH_02424	3.36e-06	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HFFBLOFH_02425	2.46e-08	-	-	-	-	-	-	-	-
HFFBLOFH_02426	1.23e-26	-	-	-	-	-	-	-	-
HFFBLOFH_02427	1.1e-147	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HFFBLOFH_02428	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFFBLOFH_02429	9.2e-317	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFFBLOFH_02430	2.09e-85	-	-	-	-	-	-	-	-
HFFBLOFH_02431	2.85e-83	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HFFBLOFH_02432	2.15e-281	-	-	-	S	-	-	-	Membrane
HFFBLOFH_02433	1.04e-59	-	-	-	S	-	-	-	Protein of unknown function (DUF3781)
HFFBLOFH_02434	1.31e-139	yoaZ	-	-	S	-	-	-	intracellular protease amidase
HFFBLOFH_02435	2.33e-56	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HFFBLOFH_02436	5.36e-76	-	-	-	-	-	-	-	-
HFFBLOFH_02437	1.46e-81	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HFFBLOFH_02438	5.31e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
HFFBLOFH_02439	3.17e-258	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HFFBLOFH_02440	2e-62	-	-	-	K	-	-	-	Helix-turn-helix domain
HFFBLOFH_02441	3.87e-115	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HFFBLOFH_02442	1.06e-72	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HFFBLOFH_02443	5.53e-114	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFFBLOFH_02444	6.79e-53	-	-	-	-	-	-	-	-
HFFBLOFH_02445	5.06e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HFFBLOFH_02446	1.6e-233	ydbI	-	-	K	-	-	-	AI-2E family transporter
HFFBLOFH_02447	9.28e-271	xylR	-	-	GK	-	-	-	ROK family
HFFBLOFH_02448	2.92e-143	-	-	-	-	-	-	-	-
HFFBLOFH_02449	3.66e-295	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HFFBLOFH_02450	3.32e-210	-	-	-	-	-	-	-	-
HFFBLOFH_02451	1.86e-256	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
HFFBLOFH_02452	9.58e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
HFFBLOFH_02453	2.47e-125	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HFFBLOFH_02454	9.69e-99	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HFFBLOFH_02455	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HFFBLOFH_02456	3.51e-252	galM3	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HFFBLOFH_02457	3.69e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HFFBLOFH_02458	1.42e-245	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HFFBLOFH_02459	2.86e-85	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
HFFBLOFH_02460	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HFFBLOFH_02461	1.23e-228	apbE3	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HFFBLOFH_02462	5.56e-167	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HFFBLOFH_02463	1.33e-274	-	-	-	G	-	-	-	Transporter
HFFBLOFH_02464	1.66e-215	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HFFBLOFH_02465	5.79e-209	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HFFBLOFH_02466	5.78e-269	-	-	-	G	-	-	-	Major Facilitator Superfamily
HFFBLOFH_02467	2.97e-83	-	-	-	-	-	-	-	-
HFFBLOFH_02468	1.78e-198	estA	-	-	S	-	-	-	Putative esterase
HFFBLOFH_02469	5.44e-174	-	-	-	K	-	-	-	UTRA domain
HFFBLOFH_02470	0.0	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFFBLOFH_02471	1.67e-208	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HFFBLOFH_02472	6.87e-202	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
HFFBLOFH_02473	2.26e-269	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HFFBLOFH_02474	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFFBLOFH_02475	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFFBLOFH_02476	3.72e-200	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HFFBLOFH_02477	2.62e-216	pbg9	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFFBLOFH_02478	5.61e-39	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HFFBLOFH_02479	1.74e-184	yxeH	-	-	S	-	-	-	hydrolase
HFFBLOFH_02480	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HFFBLOFH_02481	1.68e-146	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HFFBLOFH_02482	1.17e-305	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HFFBLOFH_02483	7.29e-61	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system galactitol-specific IIB component
HFFBLOFH_02484	1.58e-101	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFFBLOFH_02485	0.0	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFFBLOFH_02486	9.14e-146	gph3	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HFFBLOFH_02487	5.26e-247	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
HFFBLOFH_02488	8.37e-296	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HFFBLOFH_02489	6e-60	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HFFBLOFH_02490	3.99e-106	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFFBLOFH_02491	1.83e-146	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
HFFBLOFH_02492	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HFFBLOFH_02493	3.76e-180	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HFFBLOFH_02494	6.47e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HFFBLOFH_02495	8.16e-48	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HFFBLOFH_02496	3.21e-127	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HFFBLOFH_02497	3.89e-205	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HFFBLOFH_02498	0.0	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HFFBLOFH_02499	4.01e-263	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HFFBLOFH_02500	9.03e-173	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HFFBLOFH_02501	1.33e-196	nanK	-	-	GK	-	-	-	ROK family
HFFBLOFH_02502	1.86e-210	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
HFFBLOFH_02503	2.13e-159	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HFFBLOFH_02504	5.6e-292	-	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
HFFBLOFH_02505	1.05e-225	hicD1	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HFFBLOFH_02506	8.95e-60	-	-	-	-	-	-	-	-
HFFBLOFH_02507	1.99e-26	zmp1	-	-	O	-	-	-	Zinc-dependent metalloprotease
HFFBLOFH_02508	8.36e-154	rpiA2	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HFFBLOFH_02509	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
HFFBLOFH_02510	5.34e-72	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HFFBLOFH_02511	1.31e-124	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HFFBLOFH_02512	1.54e-292	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HFFBLOFH_02513	5.89e-108	-	-	-	K	-	-	-	Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HFFBLOFH_02514	2.16e-103	-	-	-	-	-	-	-	-
HFFBLOFH_02515	2.32e-101	accB3	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HFFBLOFH_02516	1.49e-223	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HFFBLOFH_02517	2.42e-207	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFFBLOFH_02518	4.06e-102	-	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
HFFBLOFH_02519	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HFFBLOFH_02520	2.7e-230	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HFFBLOFH_02521	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HFFBLOFH_02522	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HFFBLOFH_02523	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
HFFBLOFH_02524	2.14e-174	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HFFBLOFH_02525	0.0	-	-	-	M	-	-	-	domain protein
HFFBLOFH_02526	6.75e-85	-	-	-	M	-	-	-	dTDP-4-dehydrorhamnose reductase activity
HFFBLOFH_02527	1.82e-34	-	-	-	S	-	-	-	Immunity protein 74
HFFBLOFH_02528	1.89e-169	-	-	-	S	-	-	-	KR domain
HFFBLOFH_02529	2.56e-83	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HFFBLOFH_02530	1.62e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF1905)
HFFBLOFH_02531	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HFFBLOFH_02532	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HFFBLOFH_02533	2.09e-213	-	-	-	GM	-	-	-	NmrA-like family
HFFBLOFH_02534	1.15e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFFBLOFH_02535	5.93e-281	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HFFBLOFH_02536	6.58e-173	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HFFBLOFH_02537	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HFFBLOFH_02538	7.81e-148	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HFFBLOFH_02539	5.78e-269	-	-	-	EGP	-	-	-	Major Facilitator
HFFBLOFH_02540	3.25e-81	ytcD	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HFFBLOFH_02541	1.06e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HFFBLOFH_02542	4.13e-157	-	-	-	-	-	-	-	-
HFFBLOFH_02543	7.39e-300	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HFFBLOFH_02544	1.47e-83	-	-	-	-	-	-	-	-
HFFBLOFH_02545	3.15e-130	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HFFBLOFH_02546	2.16e-241	ynjC	-	-	S	-	-	-	Cell surface protein
HFFBLOFH_02547	2.63e-146	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HFFBLOFH_02548	5.83e-87	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HFFBLOFH_02549	6.57e-226	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
HFFBLOFH_02550	4.92e-212	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HFFBLOFH_02551	2.53e-233	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HFFBLOFH_02552	1.89e-208	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HFFBLOFH_02553	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HFFBLOFH_02554	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HFFBLOFH_02555	7.76e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HFFBLOFH_02556	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HFFBLOFH_02557	0.0	-	-	-	S	ko:K06889	-	ko00000	Alpha beta
HFFBLOFH_02558	6.07e-33	-	-	-	-	-	-	-	-
HFFBLOFH_02559	4.37e-128	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HFFBLOFH_02560	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HFFBLOFH_02561	2.6e-212	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
HFFBLOFH_02562	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HFFBLOFH_02563	1.53e-213	mleR	-	-	K	-	-	-	LysR family
HFFBLOFH_02564	4.54e-207	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
HFFBLOFH_02565	2.32e-121	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HFFBLOFH_02566	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HFFBLOFH_02567	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HFFBLOFH_02582	1.08e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HFFBLOFH_02583	2.81e-178	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HFFBLOFH_02584	9.28e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HFFBLOFH_02585	7.12e-170	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HFFBLOFH_02586	1.64e-17	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HFFBLOFH_02587	1.52e-231	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HFFBLOFH_02588	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HFFBLOFH_02589	2.24e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
HFFBLOFH_02590	1.83e-156	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HFFBLOFH_02591	1.29e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HFFBLOFH_02592	6.31e-222	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HFFBLOFH_02593	7.21e-150	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HFFBLOFH_02594	1.6e-246	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HFFBLOFH_02595	2.68e-75	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HFFBLOFH_02596	9.52e-264	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
HFFBLOFH_02597	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HFFBLOFH_02598	1.12e-207	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HFFBLOFH_02600	3.59e-301	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HFFBLOFH_02601	2.5e-147	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HFFBLOFH_02602	4.97e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HFFBLOFH_02603	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HFFBLOFH_02604	1.97e-110	-	-	-	S	-	-	-	Pfam:DUF3816
HFFBLOFH_02605	1.21e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HFFBLOFH_02606	1.27e-143	-	-	-	-	-	-	-	-
HFFBLOFH_02607	1.08e-229	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HFFBLOFH_02608	3.84e-185	-	-	-	S	-	-	-	Peptidase_C39 like family
HFFBLOFH_02609	1.04e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HFFBLOFH_02610	3.38e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HFFBLOFH_02611	9.38e-189	-	-	-	KT	-	-	-	helix_turn_helix, mercury resistance
HFFBLOFH_02612	3.41e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HFFBLOFH_02613	1.86e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HFFBLOFH_02614	1.2e-240	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HFFBLOFH_02615	1.18e-155	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFFBLOFH_02616	2.76e-117	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
HFFBLOFH_02617	5.72e-238	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HFFBLOFH_02618	3.55e-127	ywjB	-	-	H	-	-	-	RibD C-terminal domain
HFFBLOFH_02619	9.35e-257	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HFFBLOFH_02620	7.1e-152	-	-	-	S	-	-	-	Membrane
HFFBLOFH_02621	2.11e-199	mleP3	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HFFBLOFH_02622	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
HFFBLOFH_02623	2.8e-63	-	-	-	-	-	-	-	-
HFFBLOFH_02624	1.23e-75	-	-	-	-	-	-	-	-
HFFBLOFH_02625	1.86e-210	-	-	-	-	-	-	-	-
HFFBLOFH_02626	1.4e-95	-	-	-	K	-	-	-	Transcriptional regulator
HFFBLOFH_02627	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
HFFBLOFH_02628	8.94e-221	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HFFBLOFH_02629	7.2e-61	-	-	-	S	-	-	-	Enterocin A Immunity
HFFBLOFH_02630	8.34e-86	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
HFFBLOFH_02631	1.01e-161	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HFFBLOFH_02632	2.66e-172	-	-	-	-	-	-	-	-
HFFBLOFH_02633	9.38e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
HFFBLOFH_02634	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HFFBLOFH_02635	0.0	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HFFBLOFH_02636	8.97e-253	yhhX	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HFFBLOFH_02637	2.48e-227	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HFFBLOFH_02638	5.91e-150	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HFFBLOFH_02639	1.48e-201	ccpB	-	-	K	-	-	-	lacI family
HFFBLOFH_02640	2.2e-157	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HFFBLOFH_02641	3.68e-203	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFFBLOFH_02642	5.02e-228	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HFFBLOFH_02643	3e-127	-	-	-	C	-	-	-	Nitroreductase family
HFFBLOFH_02644	6.04e-217	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HFFBLOFH_02645	4.2e-88	gcsH1	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Glycine cleavage H-protein
HFFBLOFH_02646	4.29e-227	-	-	-	-	-	-	-	-
HFFBLOFH_02647	3.27e-168	-	-	-	-	-	-	-	-
HFFBLOFH_02648	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
HFFBLOFH_02649	3.01e-75	-	-	-	-	-	-	-	-
HFFBLOFH_02650	3.74e-284	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFFBLOFH_02651	9.81e-33	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HFFBLOFH_02652	1.02e-98	-	-	-	K	-	-	-	Transcriptional regulator
HFFBLOFH_02653	9.59e-288	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HFFBLOFH_02654	2.18e-53	-	-	-	-	-	-	-	-
HFFBLOFH_02655	3.07e-264	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFFBLOFH_02656	1.31e-179	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFFBLOFH_02657	6.34e-190	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFFBLOFH_02658	8.8e-264	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HFFBLOFH_02659	3.68e-125	-	-	-	K	-	-	-	Cupin domain
HFFBLOFH_02660	8.08e-110	-	-	-	S	-	-	-	ASCH
HFFBLOFH_02661	1.88e-111	-	-	-	K	-	-	-	GNAT family
HFFBLOFH_02662	2.14e-117	-	-	-	K	-	-	-	acetyltransferase
HFFBLOFH_02663	2.06e-30	-	-	-	-	-	-	-	-
HFFBLOFH_02664	5.05e-79	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HFFBLOFH_02665	1.85e-208	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFFBLOFH_02666	1.08e-243	-	-	-	-	-	-	-	-
HFFBLOFH_02667	3.5e-307	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HFFBLOFH_02668	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
HFFBLOFH_02669	4.63e-119	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HFFBLOFH_02670	3.93e-59	-	-	-	-	-	-	-	-
HFFBLOFH_02671	9.42e-258	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HFFBLOFH_02672	1.15e-198	tagG	-	-	U	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HFFBLOFH_02673	1.57e-280	-	-	-	-	-	-	-	-
HFFBLOFH_02674	3.51e-281	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HFFBLOFH_02675	3.08e-81	-	-	-	S	-	-	-	CHY zinc finger
HFFBLOFH_02676	6.8e-224	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HFFBLOFH_02677	7.31e-122	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HFFBLOFH_02678	6.4e-54	-	-	-	-	-	-	-	-
HFFBLOFH_02679	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HFFBLOFH_02680	3.48e-40	-	-	-	-	-	-	-	-
HFFBLOFH_02681	5.81e-170	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HFFBLOFH_02682	2.75e-304	xylP1	-	-	G	-	-	-	MFS/sugar transport protein
HFFBLOFH_02684	8.16e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HFFBLOFH_02685	0.0	acdH	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
HFFBLOFH_02686	7.81e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HFFBLOFH_02687	3.04e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HFFBLOFH_02688	1.79e-243	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HFFBLOFH_02689	3.44e-204	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HFFBLOFH_02690	1.88e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HFFBLOFH_02691	1.54e-141	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HFFBLOFH_02692	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
HFFBLOFH_02693	3.04e-174	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HFFBLOFH_02694	4.07e-249	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HFFBLOFH_02695	3.76e-245	ampC	-	-	V	-	-	-	Beta-lactamase
HFFBLOFH_02696	8.57e-41	-	-	-	-	-	-	-	-
HFFBLOFH_02697	1.9e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HFFBLOFH_02698	1.33e-77	-	-	-	-	-	-	-	-
HFFBLOFH_02699	1.08e-181	-	-	-	-	-	-	-	-
HFFBLOFH_02700	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HFFBLOFH_02701	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HFFBLOFH_02702	1.81e-85	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HFFBLOFH_02703	2.91e-177	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
HFFBLOFH_02705	2.87e-270	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HFFBLOFH_02706	4.76e-288	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
HFFBLOFH_02707	1.81e-168	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HFFBLOFH_02708	8.63e-191	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HFFBLOFH_02709	1.01e-175	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HFFBLOFH_02710	7.16e-201	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HFFBLOFH_02711	1.4e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HFFBLOFH_02712	6.6e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HFFBLOFH_02713	3.49e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HFFBLOFH_02714	1.42e-269	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HFFBLOFH_02715	3.3e-208	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HFFBLOFH_02716	2.4e-161	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HFFBLOFH_02717	1.14e-159	vanR	-	-	K	-	-	-	response regulator
HFFBLOFH_02718	5.61e-273	hpk31	-	-	T	-	-	-	Histidine kinase
HFFBLOFH_02719	3.1e-304	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HFFBLOFH_02720	1.6e-114	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HFFBLOFH_02721	2.05e-167	-	-	-	E	-	-	-	branched-chain amino acid
HFFBLOFH_02722	5.93e-73	-	-	-	S	-	-	-	branched-chain amino acid
HFFBLOFH_02723	7.92e-140	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HFFBLOFH_02724	2.07e-40	-	-	-	-	-	-	-	-
HFFBLOFH_02725	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HFFBLOFH_02726	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HFFBLOFH_02727	1.25e-86	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HFFBLOFH_02728	6.46e-221	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
HFFBLOFH_02729	1.04e-98	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HFFBLOFH_02731	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HFFBLOFH_02732	1.53e-26	-	-	-	-	-	-	-	-
HFFBLOFH_02733	4.95e-103	-	-	-	-	-	-	-	-
HFFBLOFH_02735	1.32e-224	-	-	-	M	-	-	-	Peptidase family S41
HFFBLOFH_02736	7.34e-124	-	-	-	K	-	-	-	Helix-turn-helix domain
HFFBLOFH_02737	5.05e-05	-	-	-	S	-	-	-	FRG
HFFBLOFH_02738	6.34e-39	-	-	-	-	-	-	-	-
HFFBLOFH_02739	1.4e-13	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HFFBLOFH_02740	7.1e-81	-	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HFFBLOFH_02741	9.04e-78	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
HFFBLOFH_02742	1.11e-59	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HFFBLOFH_02743	1.26e-137	-	-	-	L	-	-	-	Integrase
HFFBLOFH_02744	2.08e-60	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
HFFBLOFH_02745	3.03e-49	-	-	-	K	-	-	-	sequence-specific DNA binding
HFFBLOFH_02746	9.13e-70	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
HFFBLOFH_02747	2.78e-231	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
HFFBLOFH_02748	1.98e-72	repA	-	-	S	-	-	-	Replication initiator protein A
HFFBLOFH_02749	1.32e-57	-	-	-	-	-	-	-	-
HFFBLOFH_02750	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HFFBLOFH_02751	1.96e-30	-	-	-	L	-	-	-	Initiator Replication protein
HFFBLOFH_02753	3.53e-38	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HFFBLOFH_02754	1.92e-18	mpr	-	-	E	-	-	-	Trypsin-like serine protease
HFFBLOFH_02756	3.53e-65	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HFFBLOFH_02757	2.63e-44	-	-	-	-	-	-	-	-
HFFBLOFH_02758	2.96e-246	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HFFBLOFH_02759	4.33e-162	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain protein
HFFBLOFH_02760	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HFFBLOFH_02761	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HFFBLOFH_02762	5.79e-08	-	-	-	-	-	-	-	-
HFFBLOFH_02763	8.94e-91	-	-	-	-	-	-	-	-
HFFBLOFH_02764	0.0	-	-	-	S	-	-	-	MucBP domain
HFFBLOFH_02765	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HFFBLOFH_02766	4.33e-205	-	-	-	K	-	-	-	LysR substrate binding domain
HFFBLOFH_02767	1.85e-201	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
HFFBLOFH_02768	0.0	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HFFBLOFH_02769	0.0	lepA2	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HFFBLOFH_02770	6.88e-152	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFFBLOFH_02771	7.19e-89	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HFFBLOFH_02772	9.45e-299	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HFFBLOFH_02773	3.74e-302	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HFFBLOFH_02774	2.83e-206	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFFBLOFH_02775	2.91e-190	malA	-	-	S	-	-	-	maltodextrose utilization protein MalA
HFFBLOFH_02776	0.0	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
HFFBLOFH_02777	2.44e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFFBLOFH_02778	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HFFBLOFH_02779	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
HFFBLOFH_02780	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HFFBLOFH_02781	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HFFBLOFH_02782	1.08e-221	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
HFFBLOFH_02783	0.0	treP	2.4.1.64	GH65	G	ko:K05342	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HFFBLOFH_02784	1.3e-203	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HFFBLOFH_02785	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFFBLOFH_02786	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFFBLOFH_02787	3.26e-102	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HFFBLOFH_02788	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HFFBLOFH_02789	2.66e-132	-	-	-	G	-	-	-	Glycogen debranching enzyme
HFFBLOFH_02790	5.6e-14	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HFFBLOFH_02791	6.72e-208	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HFFBLOFH_02792	2.02e-192	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
HFFBLOFH_02793	1.04e-94	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HFFBLOFH_02794	1.1e-93	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HFFBLOFH_02795	5.74e-32	-	-	-	-	-	-	-	-
HFFBLOFH_02796	1.37e-116	-	-	-	-	-	-	-	-
HFFBLOFH_02797	1.81e-50	ydaS	-	-	S	-	-	-	Transglycosylase associated protein
HFFBLOFH_02798	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase family
HFFBLOFH_02799	1.71e-59	-	-	-	S	-	-	-	MORN repeat
HFFBLOFH_02800	3.39e-52	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HFFBLOFH_02801	5.3e-157	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HFFBLOFH_02802	4.29e-101	-	-	-	-	-	-	-	-
HFFBLOFH_02803	5.09e-51	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HFFBLOFH_02804	2.42e-127	-	-	-	FG	-	-	-	HIT domain
HFFBLOFH_02805	4.27e-223	ydhF	-	-	S	-	-	-	Aldo keto reductase
HFFBLOFH_02806	5.17e-70	-	-	-	S	-	-	-	Pfam:DUF59
HFFBLOFH_02807	4.56e-206	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HFFBLOFH_02808	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HFFBLOFH_02809	1.87e-249	-	-	-	V	-	-	-	Beta-lactamase
HFFBLOFH_02810	3.74e-125	-	-	-	V	-	-	-	VanZ like family
HFFBLOFH_02811	6.02e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HFFBLOFH_02812	7.81e-241	-	-	-	S	-	-	-	Cell surface protein
HFFBLOFH_02813	3.15e-98	-	-	-	-	-	-	-	-
HFFBLOFH_02814	0.0	-	-	-	-	-	-	-	-
HFFBLOFH_02815	3.56e-288	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HFFBLOFH_02816	2.97e-51	-	-	-	S	ko:K07343	-	ko00000	TfoX C-terminal domain
HFFBLOFH_02817	2.81e-181	-	-	-	K	-	-	-	Helix-turn-helix domain
HFFBLOFH_02818	4.31e-179	-	-	-	-	-	-	-	-
HFFBLOFH_02819	2.82e-236	-	-	-	S	-	-	-	DUF218 domain
HFFBLOFH_02820	3.26e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFFBLOFH_02821	9.06e-193	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HFFBLOFH_02822	5.78e-292	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HFFBLOFH_02823	1.96e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HFFBLOFH_02824	5.3e-49	-	-	-	-	-	-	-	-
HFFBLOFH_02825	2.95e-57	-	-	-	S	-	-	-	ankyrin repeats
HFFBLOFH_02826	5.13e-119	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HFFBLOFH_02827	7.59e-64	-	-	-	-	-	-	-	-
HFFBLOFH_02828	6.83e-274	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
HFFBLOFH_02829	8.05e-178	-	-	-	F	-	-	-	NUDIX domain
HFFBLOFH_02830	2.68e-32	-	-	-	-	-	-	-	-
HFFBLOFH_02832	8.51e-209	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HFFBLOFH_02833	1.23e-222	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
HFFBLOFH_02834	3.43e-106	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
HFFBLOFH_02835	2.29e-48	-	-	-	-	-	-	-	-
HFFBLOFH_02836	4.54e-45	-	-	-	-	-	-	-	-
HFFBLOFH_02837	9.39e-277	-	-	-	T	-	-	-	diguanylate cyclase
HFFBLOFH_02838	6.66e-115	-	-	-	-	-	-	-	-
HFFBLOFH_02839	2.29e-225	-	-	-	L	-	-	-	Initiator Replication protein
HFFBLOFH_02840	3.67e-41	-	-	-	-	-	-	-	-
HFFBLOFH_02841	1.87e-139	-	-	-	L	-	-	-	Integrase
HFFBLOFH_02842	4.17e-55	-	-	-	K	-	-	-	prlF antitoxin for toxin YhaV_toxin
HFFBLOFH_02843	1.03e-77	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HFFBLOFH_02844	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
HFFBLOFH_02847	2.55e-218	-	-	-	EG	-	-	-	EamA-like transporter family
HFFBLOFH_02848	1.06e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HFFBLOFH_02849	2.12e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HFFBLOFH_02850	1.45e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HFFBLOFH_02851	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HFFBLOFH_02852	5.23e-277	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HFFBLOFH_02853	2.51e-200	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HFFBLOFH_02854	2.78e-80	-	-	-	M	-	-	-	Cna protein B-type domain
HFFBLOFH_02855	0.0	merA	1.16.1.1	-	C	ko:K00520,ko:K21739	-	ko00000,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HFFBLOFH_02856	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
HFFBLOFH_02857	4.67e-35	-	-	-	-	-	-	-	-
HFFBLOFH_02858	6.04e-43	-	-	-	-	-	-	-	-
HFFBLOFH_02859	1.74e-18	-	-	-	Q	-	-	-	Methyltransferase
HFFBLOFH_02860	9.51e-142	XK27_07075	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HFFBLOFH_02861	1.07e-74	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HFFBLOFH_02862	2.13e-167	-	-	-	L	-	-	-	Helix-turn-helix domain
HFFBLOFH_02863	4.73e-206	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HFFBLOFH_02864	6.16e-298	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
HFFBLOFH_02867	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HFFBLOFH_02868	2.43e-241	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
HFFBLOFH_02869	2.64e-129	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
HFFBLOFH_02870	2.1e-78	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
HFFBLOFH_02871	1.54e-125	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFFBLOFH_02872	4.2e-22	-	-	-	-	-	-	-	-
HFFBLOFH_02873	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HFFBLOFH_02874	1.01e-117	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
HFFBLOFH_02875	5.87e-51	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
HFFBLOFH_02876	3.99e-101	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HFFBLOFH_02877	2.17e-304	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HFFBLOFH_02878	0.0	-	-	-	C	-	-	-	FMN_bind
HFFBLOFH_02879	3.55e-169	-	-	-	K	-	-	-	LysR family
HFFBLOFH_02880	1.61e-74	mleR	-	-	K	-	-	-	LysR substrate binding domain
HFFBLOFH_02881	7.43e-130	padR	-	-	K	-	-	-	Virulence activator alpha C-term
HFFBLOFH_02882	2.51e-103	-	-	-	T	-	-	-	Universal stress protein family
HFFBLOFH_02883	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HFFBLOFH_02885	7.39e-83	-	-	-	G	-	-	-	COG0662 Mannose-6-phosphate isomerase
HFFBLOFH_02886	2.85e-57	-	-	-	-	-	-	-	-
HFFBLOFH_02887	2.06e-66	ykoF	-	-	S	-	-	-	YKOF-related Family
HFFBLOFH_02888	5.63e-15	-	-	-	E	-	-	-	glutamine synthetase
HFFBLOFH_02889	9.73e-245	-	-	-	E	-	-	-	glutamine synthetase
HFFBLOFH_02890	3.2e-76	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HFFBLOFH_02891	3.16e-59	-	-	-	T	ko:K07172	-	ko00000,ko02048	Antidote-toxin recognition MazE, bacterial antitoxin
HFFBLOFH_02892	9.24e-140	-	-	-	L	-	-	-	Integrase
HFFBLOFH_02893	3.72e-21	-	-	-	-	-	-	-	-
HFFBLOFH_02894	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HFFBLOFH_02895	5.49e-237	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HFFBLOFH_02896	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HFFBLOFH_02898	2.37e-49	-	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
HFFBLOFH_02899	9.57e-315	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HFFBLOFH_02900	7.8e-75	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
HFFBLOFH_02901	1.19e-124	-	-	-	L	-	-	-	Resolvase, N terminal domain
HFFBLOFH_02902	1.28e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Transcriptional regulator
HFFBLOFH_02903	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HFFBLOFH_02904	9.4e-148	mdt(A)	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Major facilitator Superfamily
HFFBLOFH_02905	2.09e-151	-	-	-	-	-	-	-	-
HFFBLOFH_02906	1.16e-84	-	-	-	-	-	-	-	-
HFFBLOFH_02907	1.48e-81	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFFBLOFH_02908	5.32e-298	aspD	4.1.1.12	-	E	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	ko00000,ko00001,ko01000	Aminotransferase class I and II
HFFBLOFH_02909	9.33e-249	-	-	-	U	ko:K07085	-	ko00000	Predicted Permease Membrane Region
HFFBLOFH_02910	6.47e-10	-	-	-	P	-	-	-	Cation efflux family
HFFBLOFH_02911	8.86e-35	-	-	-	-	-	-	-	-
HFFBLOFH_02912	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
HFFBLOFH_02913	2.44e-303	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HFFBLOFH_02914	1.89e-71	-	-	-	-	-	-	-	-
HFFBLOFH_02915	7.86e-68	-	-	-	L	-	-	-	Transposase IS66 family
HFFBLOFH_02916	2.89e-256	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HFFBLOFH_02917	3.9e-34	-	-	-	-	-	-	-	-
HFFBLOFH_02918	5.03e-75	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
HFFBLOFH_02919	4.16e-06	-	-	-	S	-	-	-	Transposase C of IS166 homeodomain
HFFBLOFH_02920	1.95e-25	-	-	-	-	-	-	-	-
HFFBLOFH_02921	3.1e-172	repA	-	-	S	-	-	-	Replication initiator protein A
HFFBLOFH_02922	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HFFBLOFH_02925	4.87e-45	-	-	-	-	-	-	-	-
HFFBLOFH_02926	8.69e-185	-	-	-	D	-	-	-	AAA domain
HFFBLOFH_02927	5.62e-49	kdpE	-	-	KT	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HFFBLOFH_02928	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HFFBLOFH_02929	1.74e-72	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HFFBLOFH_02930	5.17e-70	-	-	-	S	-	-	-	Nitroreductase
HFFBLOFH_02931	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HFFBLOFH_02932	4.21e-174	bgaR	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HFFBLOFH_02933	4.31e-196	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HFFBLOFH_02934	1.39e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFFBLOFH_02935	3.23e-150	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
HFFBLOFH_02936	4.27e-146	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
HFFBLOFH_02938	1.95e-62	-	-	-	S	-	-	-	Family of unknown function (DUF5388)
HFFBLOFH_02939	6.89e-190	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
HFFBLOFH_02940	3.77e-278	-	-	-	EGP	-	-	-	Major Facilitator
HFFBLOFH_02941	1.62e-150	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HFFBLOFH_02942	8.61e-19	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	adenosylhomocysteinase activity
HFFBLOFH_02943	5.41e-89	-	-	-	C	-	-	-	lyase activity
HFFBLOFH_02944	2.64e-233	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HFFBLOFH_02945	3.79e-26	-	-	-	-	-	-	-	-
HFFBLOFH_02947	4.93e-54	-	-	-	-	-	-	-	-
HFFBLOFH_02948	1.39e-36	-	-	-	-	-	-	-	-
HFFBLOFH_02949	7.57e-122	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFFBLOFH_02950	3.47e-244	-	1.1.1.219	-	GM	ko:K00091	-	ko00000,ko01000	Male sterility protein
HFFBLOFH_02951	1.27e-129	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HFFBLOFH_02952	5.11e-59	-	-	-	S	-	-	-	Bacteriophage holin
HFFBLOFH_02953	2.93e-73	-	-	-	V	-	-	-	Abortive infection bacteriophage resistance protein
HFFBLOFH_02954	2.83e-58	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
HFFBLOFH_02955	6.45e-111	-	-	-	-	-	-	-	-
HFFBLOFH_02956	8.5e-55	-	-	-	-	-	-	-	-
HFFBLOFH_02957	1.34e-34	-	-	-	-	-	-	-	-
HFFBLOFH_02958	2.62e-160	-	-	-	S	-	-	-	Phage Mu protein F like protein
HFFBLOFH_02959	3.62e-22	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
HFFBLOFH_02960	9.4e-122	-	-	-	L	-	-	-	4.5 Transposon and IS
HFFBLOFH_02961	1.15e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase
HFFBLOFH_02963	5.15e-174	-	-	-	L	-	-	-	Replication protein
HFFBLOFH_02964	6.03e-36	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFFBLOFH_02965	3.11e-17	-	-	-	S	-	-	-	protein with an alpha beta hydrolase fold
HFFBLOFH_02966	2.03e-31	-	-	-	S	-	-	-	Family of unknown function (DUF5388)
HFFBLOFH_02967	1.18e-184	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
HFFBLOFH_02969	6.13e-127	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
HFFBLOFH_02970	1.91e-34	-	-	-	-	-	-	-	-
HFFBLOFH_02971	2.44e-54	-	-	-	-	-	-	-	-
HFFBLOFH_02972	1.32e-107	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HFFBLOFH_02973	2.26e-39	-	-	-	L	-	-	-	manually curated
HFFBLOFH_02974	1.18e-192	degV	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HFFBLOFH_02975	2.67e-75	-	-	-	-	-	-	-	-
HFFBLOFH_02976	2.54e-42	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HFFBLOFH_02977	4.19e-54	-	-	-	-	-	-	-	-
HFFBLOFH_02978	1.18e-194	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HFFBLOFH_02979	1.25e-283	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HFFBLOFH_02980	3.12e-201	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HFFBLOFH_02981	9.51e-135	-	-	-	-	-	-	-	-
HFFBLOFH_02982	3.72e-14	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
HFFBLOFH_02983	1.41e-163	-	-	-	P	-	-	-	integral membrane protein, YkoY family
HFFBLOFH_02985	3.47e-47	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
HFFBLOFH_02986	4.05e-211	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HFFBLOFH_02987	3.55e-76	-	-	-	-	-	-	-	-
HFFBLOFH_02988	2.43e-91	-	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
HFFBLOFH_02989	6.01e-49	-	-	-	S	-	-	-	Bacteriophage holin
HFFBLOFH_02990	2.58e-147	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HFFBLOFH_02991	8.81e-48	-	-	-	L	-	-	-	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HFFBLOFH_02993	4.64e-18	-	-	-	-	-	-	-	-
HFFBLOFH_02995	1.95e-114	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
HFFBLOFH_02996	3.76e-115	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HFFBLOFH_02997	8.37e-108	-	-	-	L	-	-	-	Transposase DDE domain
HFFBLOFH_02998	2.69e-105	-	-	-	L	ko:K07498	-	ko00000	DDE domain