Read a JSON File

ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
KIOEMHBE_00002	2.16e-208	-	-	-	K	-	-	-	Transcriptional regulator
KIOEMHBE_00003	2.43e-206	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
KIOEMHBE_00004	1.66e-211	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
KIOEMHBE_00005	5.73e-100	-	-	-	K	-	-	-	Winged helix DNA-binding domain
KIOEMHBE_00006	0.0	ycaM	-	-	E	-	-	-	amino acid
KIOEMHBE_00007	2.38e-164	aroC1	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
KIOEMHBE_00008	4.3e-44	-	-	-	-	-	-	-	-
KIOEMHBE_00009	0.0	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
KIOEMHBE_00010	9.78e-187	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
KIOEMHBE_00011	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
KIOEMHBE_00012	4.75e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
KIOEMHBE_00013	0.0	-	-	-	-	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	-
KIOEMHBE_00014	1.54e-131	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
KIOEMHBE_00015	1.96e-224	serA1	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
KIOEMHBE_00016	3.98e-204	-	-	-	EG	-	-	-	EamA-like transporter family
KIOEMHBE_00017	6.86e-232	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KIOEMHBE_00018	5.06e-196	-	-	-	S	-	-	-	hydrolase
KIOEMHBE_00019	7.63e-107	-	-	-	-	-	-	-	-
KIOEMHBE_00020	1.75e-156	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
KIOEMHBE_00021	1.4e-181	epsV	-	-	S	-	-	-	glycosyl transferase family 2
KIOEMHBE_00022	1.23e-166	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
KIOEMHBE_00023	1.86e-64	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
KIOEMHBE_00024	6.7e-74	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
KIOEMHBE_00025	0.0	pbg5	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KIOEMHBE_00026	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KIOEMHBE_00027	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
KIOEMHBE_00028	4.29e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
KIOEMHBE_00029	9.24e-231	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
KIOEMHBE_00030	6.09e-152	-	-	-	K	-	-	-	Transcriptional regulator
KIOEMHBE_00031	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KIOEMHBE_00032	7.54e-115	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
KIOEMHBE_00033	4.43e-294	-	-	-	S	-	-	-	Sterol carrier protein domain
KIOEMHBE_00034	2.45e-269	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
KIOEMHBE_00035	3.25e-48	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
KIOEMHBE_00036	5.41e-172	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
KIOEMHBE_00037	2.26e-91	-	-	-	FG	-	-	-	Scavenger mRNA decapping enzyme C-term binding
KIOEMHBE_00038	1.13e-132	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
KIOEMHBE_00039	5.88e-142	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
KIOEMHBE_00040	2.99e-38	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
KIOEMHBE_00041	4.65e-186	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
KIOEMHBE_00042	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
KIOEMHBE_00043	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
KIOEMHBE_00045	1.21e-69	-	-	-	-	-	-	-	-
KIOEMHBE_00046	1.52e-151	-	-	-	-	-	-	-	-
KIOEMHBE_00047	1.16e-110	-	-	-	F	-	-	-	belongs to the nudix hydrolase family
KIOEMHBE_00048	3.03e-299	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
KIOEMHBE_00049	4.79e-13	-	-	-	-	-	-	-	-
KIOEMHBE_00050	5.92e-67	-	-	-	-	-	-	-	-
KIOEMHBE_00051	1.76e-114	-	-	-	-	-	-	-	-
KIOEMHBE_00052	5.7e-95	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
KIOEMHBE_00053	3.64e-46	-	-	-	-	-	-	-	-
KIOEMHBE_00054	1.1e-103	usp5	-	-	T	-	-	-	universal stress protein
KIOEMHBE_00055	4.21e-175	-	-	-	-	-	-	-	-
KIOEMHBE_00056	7.89e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KIOEMHBE_00057	8.2e-81	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
KIOEMHBE_00058	1.87e-53	-	-	-	-	-	-	-	-
KIOEMHBE_00059	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
KIOEMHBE_00060	2.05e-178	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KIOEMHBE_00061	3.7e-233	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
KIOEMHBE_00062	6.89e-190	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KIOEMHBE_00063	5.95e-153	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
KIOEMHBE_00064	4.81e-188	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
KIOEMHBE_00065	5.76e-243	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
KIOEMHBE_00066	9.92e-143	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
KIOEMHBE_00067	4.57e-304	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
KIOEMHBE_00068	3.77e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KIOEMHBE_00069	2.87e-270	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KIOEMHBE_00070	3.39e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
KIOEMHBE_00071	1.17e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KIOEMHBE_00072	6.91e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KIOEMHBE_00073	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KIOEMHBE_00074	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KIOEMHBE_00075	4.22e-243	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
KIOEMHBE_00076	5.35e-133	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KIOEMHBE_00077	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
KIOEMHBE_00078	9.06e-279	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
KIOEMHBE_00079	1.83e-157	-	-	-	E	-	-	-	Methionine synthase
KIOEMHBE_00080	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
KIOEMHBE_00081	1.85e-121	-	-	-	-	-	-	-	-
KIOEMHBE_00082	1.25e-199	-	-	-	T	-	-	-	EAL domain
KIOEMHBE_00083	2.24e-206	-	-	-	GM	-	-	-	NmrA-like family
KIOEMHBE_00084	5.67e-280	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
KIOEMHBE_00085	3.1e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
KIOEMHBE_00086	0.0	pucR_2	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
KIOEMHBE_00087	7.13e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KIOEMHBE_00088	2.02e-219	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
KIOEMHBE_00089	1.61e-308	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KIOEMHBE_00090	2.76e-271	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
KIOEMHBE_00091	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
KIOEMHBE_00092	1.04e-218	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KIOEMHBE_00093	1.55e-161	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KIOEMHBE_00094	5.46e-145	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KIOEMHBE_00095	1.12e-216	oroP	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
KIOEMHBE_00096	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
KIOEMHBE_00097	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
KIOEMHBE_00098	3.86e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
KIOEMHBE_00099	1.29e-148	-	-	-	GM	-	-	-	NAD(P)H-binding
KIOEMHBE_00100	6.68e-207	mleR	-	-	K	-	-	-	LysR family
KIOEMHBE_00101	2.09e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
KIOEMHBE_00102	3.59e-26	-	-	-	-	-	-	-	-
KIOEMHBE_00103	1.84e-204	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KIOEMHBE_00104	1.02e-277	araT2	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
KIOEMHBE_00105	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	Bacterial regulatory proteins, gntR family
KIOEMHBE_00106	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KIOEMHBE_00107	4.71e-74	-	-	-	S	-	-	-	SdpI/YhfL protein family
KIOEMHBE_00108	4.68e-161	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
KIOEMHBE_00109	9.75e-39	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
KIOEMHBE_00110	3.45e-83	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
KIOEMHBE_00111	2.03e-271	yttB	-	-	EGP	-	-	-	Major Facilitator
KIOEMHBE_00112	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
KIOEMHBE_00113	1.18e-114	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
KIOEMHBE_00114	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
KIOEMHBE_00115	2.97e-76	-	-	-	-	-	-	-	-
KIOEMHBE_00116	2.61e-96	hsp2	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
KIOEMHBE_00117	1.55e-79	-	-	-	-	-	-	-	-
KIOEMHBE_00118	1.7e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
KIOEMHBE_00119	8.05e-179	rrp8	-	-	K	-	-	-	LytTr DNA-binding domain
KIOEMHBE_00120	1.97e-150	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
KIOEMHBE_00121	2.48e-178	-	-	-	-	-	-	-	-
KIOEMHBE_00122	4.75e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KIOEMHBE_00123	3.53e-169	-	-	-	K	-	-	-	Transcriptional regulator
KIOEMHBE_00124	2.01e-209	-	-	-	S	-	-	-	Putative esterase
KIOEMHBE_00125	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
KIOEMHBE_00126	1.25e-283	-	-	-	M	-	-	-	Glycosyl transferases group 1
KIOEMHBE_00127	1.38e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
KIOEMHBE_00128	4.05e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
KIOEMHBE_00129	2.5e-203	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
KIOEMHBE_00130	2.51e-103	uspA3	-	-	T	-	-	-	universal stress protein
KIOEMHBE_00131	0.0	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
KIOEMHBE_00132	4.26e-250	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
KIOEMHBE_00133	4.15e-78	-	-	-	-	-	-	-	-
KIOEMHBE_00134	1.65e-97	-	-	-	-	-	-	-	-
KIOEMHBE_00135	6.94e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2798)
KIOEMHBE_00136	2.57e-70	-	-	-	-	-	-	-	-
KIOEMHBE_00137	3.89e-62	-	-	-	-	-	-	-	-
KIOEMHBE_00138	3.87e-262	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
KIOEMHBE_00139	9.89e-74	ytpP	-	-	CO	-	-	-	Thioredoxin
KIOEMHBE_00140	1.19e-186	-	-	-	S	ko:K06889	-	ko00000	Dienelactone hydrolase family
KIOEMHBE_00141	1.83e-37	-	-	-	-	-	-	-	-
KIOEMHBE_00142	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
KIOEMHBE_00143	2.8e-63	-	-	-	-	-	-	-	-
KIOEMHBE_00144	1.23e-75	-	-	-	-	-	-	-	-
KIOEMHBE_00145	1.86e-210	-	-	-	-	-	-	-	-
KIOEMHBE_00146	1.4e-95	-	-	-	K	-	-	-	Transcriptional regulator
KIOEMHBE_00147	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
KIOEMHBE_00148	8.94e-221	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
KIOEMHBE_00149	7.2e-61	-	-	-	S	-	-	-	Enterocin A Immunity
KIOEMHBE_00150	8.34e-86	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
KIOEMHBE_00151	1.01e-161	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
KIOEMHBE_00152	2.66e-172	-	-	-	-	-	-	-	-
KIOEMHBE_00153	9.38e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
KIOEMHBE_00154	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KIOEMHBE_00155	0.0	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
KIOEMHBE_00156	8.97e-253	yhhX	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
KIOEMHBE_00157	2.48e-227	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
KIOEMHBE_00158	5.91e-150	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
KIOEMHBE_00159	1.48e-201	ccpB	-	-	K	-	-	-	lacI family
KIOEMHBE_00160	2.2e-157	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
KIOEMHBE_00161	3.68e-203	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KIOEMHBE_00162	5.02e-228	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
KIOEMHBE_00163	3e-127	-	-	-	C	-	-	-	Nitroreductase family
KIOEMHBE_00164	6.04e-217	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
KIOEMHBE_00165	2.14e-183	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KIOEMHBE_00166	2.71e-234	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
KIOEMHBE_00167	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
KIOEMHBE_00168	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KIOEMHBE_00169	6.05e-98	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
KIOEMHBE_00170	1.78e-279	-	-	-	M	-	-	-	domain protein
KIOEMHBE_00171	6.32e-67	-	-	-	M	-	-	-	domain protein
KIOEMHBE_00172	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
KIOEMHBE_00173	1.06e-145	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
KIOEMHBE_00174	1.45e-46	-	-	-	-	-	-	-	-
KIOEMHBE_00175	5.48e-236	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KIOEMHBE_00176	1.97e-254	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KIOEMHBE_00177	4.54e-126	-	-	-	J	-	-	-	glyoxalase III activity
KIOEMHBE_00178	1.01e-189	-	-	-	GM	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
KIOEMHBE_00179	4.73e-118	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
KIOEMHBE_00180	6.7e-74	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
KIOEMHBE_00181	7.28e-213	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
KIOEMHBE_00182	3.72e-283	ysaA	-	-	V	-	-	-	RDD family
KIOEMHBE_00183	4.54e-208	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
KIOEMHBE_00184	2.3e-275	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KIOEMHBE_00185	1.69e-151	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KIOEMHBE_00186	7.8e-299	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KIOEMHBE_00187	2.46e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
KIOEMHBE_00188	2.23e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KIOEMHBE_00189	5.62e-165	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KIOEMHBE_00190	1.27e-172	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KIOEMHBE_00191	6.12e-78	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KIOEMHBE_00192	1.07e-68	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
KIOEMHBE_00193	1.9e-258	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KIOEMHBE_00194	2.47e-125	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
KIOEMHBE_00195	1.18e-175	yceF	-	-	P	ko:K05794	-	ko00000	membrane
KIOEMHBE_00196	9.51e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
KIOEMHBE_00197	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
KIOEMHBE_00198	1.32e-178	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KIOEMHBE_00199	6.03e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
KIOEMHBE_00200	9.31e-225	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
KIOEMHBE_00201	1.53e-213	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
KIOEMHBE_00202	6.08e-312	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
KIOEMHBE_00203	6.83e-292	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
KIOEMHBE_00204	3.45e-209	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
KIOEMHBE_00205	1.31e-242	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KIOEMHBE_00206	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
KIOEMHBE_00207	2.64e-61	-	-	-	-	-	-	-	-
KIOEMHBE_00208	2.35e-106	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KIOEMHBE_00209	9.24e-140	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
KIOEMHBE_00210	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
KIOEMHBE_00211	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KIOEMHBE_00212	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KIOEMHBE_00213	2.18e-182	ybbR	-	-	S	-	-	-	YbbR-like protein
KIOEMHBE_00214	2.39e-191	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KIOEMHBE_00215	8.06e-156	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
KIOEMHBE_00216	3.07e-119	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
KIOEMHBE_00217	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
KIOEMHBE_00218	6.24e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
KIOEMHBE_00219	3.09e-213	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
KIOEMHBE_00220	2.53e-198	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
KIOEMHBE_00221	2.41e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
KIOEMHBE_00222	2.52e-114	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
KIOEMHBE_00223	1.29e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
KIOEMHBE_00224	1.23e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
KIOEMHBE_00225	1.4e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KIOEMHBE_00226	1.98e-199	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
KIOEMHBE_00227	7.98e-137	-	-	-	-	-	-	-	-
KIOEMHBE_00228	9.36e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KIOEMHBE_00229	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KIOEMHBE_00230	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
KIOEMHBE_00231	2.4e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KIOEMHBE_00232	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KIOEMHBE_00233	3.83e-179	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
KIOEMHBE_00234	3.55e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
KIOEMHBE_00235	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
KIOEMHBE_00236	2.83e-168	-	-	-	-	-	-	-	-
KIOEMHBE_00237	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KIOEMHBE_00238	7.15e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KIOEMHBE_00239	1.31e-285	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
KIOEMHBE_00240	2.02e-245	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KIOEMHBE_00241	5.75e-242	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
KIOEMHBE_00242	1.14e-311	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
KIOEMHBE_00244	5.11e-133	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KIOEMHBE_00245	8.58e-223	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KIOEMHBE_00246	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
KIOEMHBE_00247	1.21e-215	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
KIOEMHBE_00248	5.32e-242	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
KIOEMHBE_00249	1.71e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
KIOEMHBE_00250	3.51e-113	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
KIOEMHBE_00251	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
KIOEMHBE_00252	7.5e-302	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
KIOEMHBE_00253	2.21e-113	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KIOEMHBE_00254	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KIOEMHBE_00255	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KIOEMHBE_00256	3.85e-151	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
KIOEMHBE_00257	5.33e-268	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
KIOEMHBE_00258	1.89e-134	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
KIOEMHBE_00259	0.0	nox2	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
KIOEMHBE_00260	5.9e-170	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
KIOEMHBE_00261	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
KIOEMHBE_00262	7.54e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
KIOEMHBE_00263	4.31e-141	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
KIOEMHBE_00264	8.65e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KIOEMHBE_00265	0.0	nox	-	-	C	-	-	-	NADH oxidase
KIOEMHBE_00266	6.37e-160	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
KIOEMHBE_00267	1.13e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
KIOEMHBE_00268	4e-235	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
KIOEMHBE_00269	6.26e-213	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KIOEMHBE_00270	2.55e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KIOEMHBE_00271	2.87e-71	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
KIOEMHBE_00272	2.78e-65	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
KIOEMHBE_00273	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
KIOEMHBE_00274	4.47e-177	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KIOEMHBE_00275	9.78e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KIOEMHBE_00276	5.04e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
KIOEMHBE_00277	9.05e-206	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
KIOEMHBE_00278	2.31e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
KIOEMHBE_00279	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KIOEMHBE_00280	1.49e-170	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
KIOEMHBE_00281	1.05e-275	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
KIOEMHBE_00282	3.41e-257	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KIOEMHBE_00283	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KIOEMHBE_00284	1.27e-129	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KIOEMHBE_00285	2.94e-164	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
KIOEMHBE_00286	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
KIOEMHBE_00287	3.7e-149	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
KIOEMHBE_00288	6.57e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
KIOEMHBE_00289	7.29e-247	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
KIOEMHBE_00290	0.0	ydaO	-	-	E	-	-	-	amino acid
KIOEMHBE_00291	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KIOEMHBE_00292	9.82e-55	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KIOEMHBE_00293	2.38e-140	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
KIOEMHBE_00294	3.67e-154	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KIOEMHBE_00295	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
KIOEMHBE_00296	3.62e-249	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KIOEMHBE_00297	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KIOEMHBE_00298	4.66e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
KIOEMHBE_00299	6.84e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
KIOEMHBE_00300	3.46e-242	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
KIOEMHBE_00301	3.8e-176	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KIOEMHBE_00302	2.18e-176	phnE2	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter permease
KIOEMHBE_00303	3.33e-184	phnE1	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KIOEMHBE_00304	2.8e-187	phnX	3.11.1.1	-	E	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the HAD-like hydrolase superfamily. PhnX family
KIOEMHBE_00305	5.35e-270	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
KIOEMHBE_00306	4.95e-246	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
KIOEMHBE_00307	1.29e-190	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
KIOEMHBE_00308	2.64e-213	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KIOEMHBE_00309	8.46e-77	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
KIOEMHBE_00310	2.33e-239	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
KIOEMHBE_00311	1.39e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
KIOEMHBE_00312	1.82e-152	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KIOEMHBE_00313	1.01e-51	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
KIOEMHBE_00314	6.22e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KIOEMHBE_00315	8.34e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KIOEMHBE_00316	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KIOEMHBE_00317	7.57e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KIOEMHBE_00318	6.7e-141	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
KIOEMHBE_00319	8.42e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
KIOEMHBE_00320	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KIOEMHBE_00321	2.47e-253	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KIOEMHBE_00322	2.37e-140	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
KIOEMHBE_00323	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KIOEMHBE_00324	4.82e-86	-	-	-	L	-	-	-	nuclease
KIOEMHBE_00325	1.01e-226	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
KIOEMHBE_00326	2.76e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KIOEMHBE_00327	3.72e-105	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KIOEMHBE_00328	2.69e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KIOEMHBE_00329	9.76e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KIOEMHBE_00330	2.81e-202	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KIOEMHBE_00331	1.89e-128	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
KIOEMHBE_00332	1e-39	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KIOEMHBE_00333	4.55e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
KIOEMHBE_00334	1.12e-130	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
KIOEMHBE_00335	1.44e-125	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
KIOEMHBE_00336	1.49e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KIOEMHBE_00337	1.35e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KIOEMHBE_00338	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
KIOEMHBE_00339	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KIOEMHBE_00340	4.91e-265	yacL	-	-	S	-	-	-	domain protein
KIOEMHBE_00341	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KIOEMHBE_00342	9.43e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
KIOEMHBE_00343	5.96e-69	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
KIOEMHBE_00344	1.62e-158	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KIOEMHBE_00345	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
KIOEMHBE_00346	3.22e-147	zmp2	-	-	O	-	-	-	Zinc-dependent metalloprotease
KIOEMHBE_00347	1.91e-165	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KIOEMHBE_00348	1.22e-226	-	-	-	EG	-	-	-	EamA-like transporter family
KIOEMHBE_00349	3.06e-214	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
KIOEMHBE_00350	5.37e-233	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
KIOEMHBE_00351	1.05e-172	accA1	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
KIOEMHBE_00352	1.49e-183	accD1	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KIOEMHBE_00353	1.7e-315	accC1	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
KIOEMHBE_00354	9.24e-85	accB1	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin-requiring enzyme
KIOEMHBE_00355	3.15e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KIOEMHBE_00356	4.5e-113	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
KIOEMHBE_00357	4.16e-93	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
KIOEMHBE_00358	0.0	levR	-	-	K	-	-	-	Sigma-54 interaction domain
KIOEMHBE_00359	9.05e-85	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
KIOEMHBE_00360	4.22e-216	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
KIOEMHBE_00361	4.51e-172	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
KIOEMHBE_00362	6.46e-218	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
KIOEMHBE_00363	1.53e-195	-	-	-	G	-	-	-	Peptidase_C39 like family
KIOEMHBE_00365	1.9e-198	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KIOEMHBE_00366	1.71e-302	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
KIOEMHBE_00367	3.09e-106	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
KIOEMHBE_00368	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
KIOEMHBE_00369	2.57e-94	-	-	-	-	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	-
KIOEMHBE_00370	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
KIOEMHBE_00371	1.51e-196	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KIOEMHBE_00372	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KIOEMHBE_00373	5.44e-175	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KIOEMHBE_00374	5.41e-160	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
KIOEMHBE_00375	2.92e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KIOEMHBE_00376	2.18e-174	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KIOEMHBE_00377	1.06e-195	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
KIOEMHBE_00378	1.59e-247	ysdE	-	-	P	-	-	-	Citrate transporter
KIOEMHBE_00379	3.1e-212	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
KIOEMHBE_00380	1.38e-71	-	-	-	S	-	-	-	Cupin domain
KIOEMHBE_00381	9.02e-66	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
KIOEMHBE_00385	1.75e-193	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
KIOEMHBE_00386	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
KIOEMHBE_00388	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
KIOEMHBE_00389	2.92e-118	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
KIOEMHBE_00390	9.16e-190	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
KIOEMHBE_00391	5.09e-81	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
KIOEMHBE_00392	4.61e-222	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
KIOEMHBE_00393	3.79e-57	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
KIOEMHBE_00394	4.85e-119	XK27_09665	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
KIOEMHBE_00395	0.0	-	-	-	M	-	-	-	MucBP domain
KIOEMHBE_00396	5.1e-315	-	-	-	M	-	-	-	MucBP domain
KIOEMHBE_00397	1.42e-08	-	-	-	-	-	-	-	-
KIOEMHBE_00398	1.73e-113	-	-	-	S	-	-	-	AAA domain
KIOEMHBE_00399	7.45e-180	-	-	-	K	-	-	-	sequence-specific DNA binding
KIOEMHBE_00400	2.56e-60	-	-	-	K	-	-	-	Helix-turn-helix domain
KIOEMHBE_00401	7.39e-54	-	-	-	K	-	-	-	Helix-turn-helix domain
KIOEMHBE_00402	3.93e-220	-	-	-	K	-	-	-	Transcriptional regulator
KIOEMHBE_00403	4.37e-120	-	-	-	C	-	-	-	FMN_bind
KIOEMHBE_00404	5.68e-266	-	-	-	C	-	-	-	FMN_bind
KIOEMHBE_00406	4.3e-106	-	-	-	K	-	-	-	Transcriptional regulator
KIOEMHBE_00407	1.64e-149	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KIOEMHBE_00408	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
KIOEMHBE_00409	3.39e-255	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
KIOEMHBE_00410	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
KIOEMHBE_00411	1.32e-290	-	-	-	L	-	-	-	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KIOEMHBE_00412	9.05e-55	-	-	-	-	-	-	-	-
KIOEMHBE_00413	4.95e-44	-	-	-	L	-	-	-	leucine-zipper of insertion element IS481
KIOEMHBE_00414	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
KIOEMHBE_00415	9.95e-211	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
KIOEMHBE_00416	5.06e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
KIOEMHBE_00417	2.91e-179	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
KIOEMHBE_00418	2.26e-243	-	-	-	-	-	-	-	-
KIOEMHBE_00419	1.89e-277	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
KIOEMHBE_00420	4.18e-163	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
KIOEMHBE_00421	7.84e-117	-	-	-	K	-	-	-	FR47-like protein
KIOEMHBE_00422	1.24e-155	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
KIOEMHBE_00423	3.33e-64	-	-	-	-	-	-	-	-
KIOEMHBE_00424	4.24e-246	-	-	-	I	-	-	-	alpha/beta hydrolase fold
KIOEMHBE_00425	0.0	xylP2	-	-	G	-	-	-	symporter
KIOEMHBE_00426	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KIOEMHBE_00427	9.85e-281	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
KIOEMHBE_00428	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
KIOEMHBE_00429	3.43e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
KIOEMHBE_00430	2.03e-155	azlC	-	-	E	-	-	-	branched-chain amino acid
KIOEMHBE_00431	1.75e-47	-	-	-	K	-	-	-	MerR HTH family regulatory protein
KIOEMHBE_00432	1.46e-170	-	-	-	-	-	-	-	-
KIOEMHBE_00433	2.72e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
KIOEMHBE_00434	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
KIOEMHBE_00435	7.79e-112	-	-	-	K	-	-	-	MerR HTH family regulatory protein
KIOEMHBE_00436	1.36e-77	-	-	-	-	-	-	-	-
KIOEMHBE_00437	2.94e-155	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
KIOEMHBE_00438	1.78e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
KIOEMHBE_00439	4.6e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
KIOEMHBE_00440	7.76e-100	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
KIOEMHBE_00441	2.34e-242	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
KIOEMHBE_00442	4.15e-153	-	-	-	I	-	-	-	phosphatase
KIOEMHBE_00443	3.88e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
KIOEMHBE_00444	3.03e-129	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
KIOEMHBE_00445	5.68e-117	-	-	-	K	-	-	-	Transcriptional regulator
KIOEMHBE_00446	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
KIOEMHBE_00447	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
KIOEMHBE_00448	7.48e-153	dacB	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
KIOEMHBE_00449	1.11e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
KIOEMHBE_00450	1.62e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KIOEMHBE_00458	9.78e-102	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
KIOEMHBE_00459	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KIOEMHBE_00460	1.16e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KIOEMHBE_00461	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KIOEMHBE_00462	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KIOEMHBE_00463	1.48e-149	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
KIOEMHBE_00464	4.19e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KIOEMHBE_00465	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KIOEMHBE_00466	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KIOEMHBE_00467	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
KIOEMHBE_00468	1.24e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KIOEMHBE_00469	9.83e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
KIOEMHBE_00470	2.27e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KIOEMHBE_00471	6.61e-193	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KIOEMHBE_00472	1.85e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KIOEMHBE_00473	3.59e-69	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KIOEMHBE_00474	5.46e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KIOEMHBE_00475	8.29e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KIOEMHBE_00476	1.11e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
KIOEMHBE_00477	1.96e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KIOEMHBE_00478	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KIOEMHBE_00479	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KIOEMHBE_00480	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KIOEMHBE_00481	4.99e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KIOEMHBE_00482	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KIOEMHBE_00483	1.75e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KIOEMHBE_00484	5.32e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KIOEMHBE_00485	8.44e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
KIOEMHBE_00486	1.32e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
KIOEMHBE_00487	5.95e-300	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KIOEMHBE_00488	1.84e-160	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KIOEMHBE_00489	9.87e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KIOEMHBE_00490	9.65e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KIOEMHBE_00491	7.71e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KIOEMHBE_00492	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KIOEMHBE_00493	7.76e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
KIOEMHBE_00494	1.02e-233	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
KIOEMHBE_00495	1.41e-122	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
KIOEMHBE_00496	4.42e-111	-	-	-	S	-	-	-	NusG domain II
KIOEMHBE_00497	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
KIOEMHBE_00498	3.19e-194	-	-	-	S	-	-	-	FMN_bind
KIOEMHBE_00499	3.08e-264	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KIOEMHBE_00500	1.98e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KIOEMHBE_00501	2.01e-211	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KIOEMHBE_00502	2.29e-182	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KIOEMHBE_00503	3.06e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KIOEMHBE_00504	4.58e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KIOEMHBE_00505	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
KIOEMHBE_00506	8.51e-210	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
KIOEMHBE_00507	1.68e-221	-	-	-	S	-	-	-	Membrane
KIOEMHBE_00508	9.14e-38	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
KIOEMHBE_00509	2.99e-208	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
KIOEMHBE_00510	0.0	tkt2	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KIOEMHBE_00511	1.65e-211	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KIOEMHBE_00512	3.3e-235	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	DAHP synthetase I family
KIOEMHBE_00513	1.33e-255	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KIOEMHBE_00515	1.49e-281	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
KIOEMHBE_00516	1.51e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
KIOEMHBE_00517	1.41e-147	-	4.2.1.2, 4.2.1.32	-	C	ko:K01676,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
KIOEMHBE_00518	4.28e-225	ttdA	4.2.1.32	-	C	ko:K03779	ko00630,map00630	ko00000,ko00001,ko01000	Fumarate hydratase (Fumerase)
KIOEMHBE_00519	6.07e-252	-	-	-	K	-	-	-	Helix-turn-helix domain
KIOEMHBE_00520	3.16e-196	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
KIOEMHBE_00521	2.04e-170	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
KIOEMHBE_00522	1.76e-180	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
KIOEMHBE_00523	4.26e-222	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
KIOEMHBE_00524	1.18e-66	-	-	-	-	-	-	-	-
KIOEMHBE_00525	9.2e-215	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
KIOEMHBE_00526	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
KIOEMHBE_00527	8.69e-230	citR	-	-	K	-	-	-	sugar-binding domain protein
KIOEMHBE_00528	1.11e-263	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
KIOEMHBE_00529	3.07e-241	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
KIOEMHBE_00530	1.23e-58	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
KIOEMHBE_00531	1.51e-206	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
KIOEMHBE_00532	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
KIOEMHBE_00533	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KIOEMHBE_00534	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
KIOEMHBE_00535	2.32e-121	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
KIOEMHBE_00536	4.54e-207	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
KIOEMHBE_00537	1.53e-213	mleR	-	-	K	-	-	-	LysR family
KIOEMHBE_00538	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
KIOEMHBE_00539	2.6e-212	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
KIOEMHBE_00540	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
KIOEMHBE_00541	4.37e-128	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
KIOEMHBE_00542	6.07e-33	-	-	-	-	-	-	-	-
KIOEMHBE_00543	0.0	-	-	-	S	ko:K06889	-	ko00000	Alpha beta
KIOEMHBE_00544	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
KIOEMHBE_00545	7.76e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
KIOEMHBE_00546	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
KIOEMHBE_00547	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KIOEMHBE_00548	1.89e-208	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
KIOEMHBE_00549	2.53e-233	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
KIOEMHBE_00550	4.92e-212	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
KIOEMHBE_00551	1.23e-311	-	-	-	M	ko:K07273	-	ko00000	hydrolase, family 25
KIOEMHBE_00552	1.38e-232	-	-	-	V	-	-	-	LD-carboxypeptidase
KIOEMHBE_00553	4.35e-159	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
KIOEMHBE_00554	1.9e-156	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
KIOEMHBE_00555	2.27e-247	-	-	-	-	-	-	-	-
KIOEMHBE_00556	2.13e-186	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
KIOEMHBE_00557	2.44e-267	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
KIOEMHBE_00558	3.28e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
KIOEMHBE_00559	5.89e-81	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
KIOEMHBE_00560	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
KIOEMHBE_00561	1.65e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KIOEMHBE_00562	9.72e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
KIOEMHBE_00563	1.9e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KIOEMHBE_00564	4.89e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
KIOEMHBE_00565	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
KIOEMHBE_00566	3.34e-144	-	-	-	G	-	-	-	Phosphoglycerate mutase family
KIOEMHBE_00567	1.9e-93	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
KIOEMHBE_00570	1.92e-168	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
KIOEMHBE_00571	2.08e-92	-	-	-	S	-	-	-	LuxR family transcriptional regulator
KIOEMHBE_00572	1.19e-176	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
KIOEMHBE_00573	1.37e-119	-	-	-	F	-	-	-	NUDIX domain
KIOEMHBE_00574	2.16e-208	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KIOEMHBE_00575	1.6e-171	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
KIOEMHBE_00576	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
KIOEMHBE_00577	1.97e-87	-	-	-	K	-	-	-	Transcriptional regulator
KIOEMHBE_00578	4.53e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
KIOEMHBE_00579	2.47e-101	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
KIOEMHBE_00580	1.96e-168	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
KIOEMHBE_00581	1.27e-35	-	-	-	-	-	-	-	-
KIOEMHBE_00582	2.37e-65	-	-	-	-	-	-	-	-
KIOEMHBE_00583	7.62e-161	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
KIOEMHBE_00584	6e-268	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
KIOEMHBE_00586	1.33e-67	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
KIOEMHBE_00587	9.3e-167	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
KIOEMHBE_00588	3.59e-49	XK27_00890	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
KIOEMHBE_00589	1.06e-312	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
KIOEMHBE_00590	2.05e-45	-	-	-	-	-	-	-	-
KIOEMHBE_00591	7.79e-78	-	-	-	-	-	-	-	-
KIOEMHBE_00592	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
KIOEMHBE_00593	4.76e-290	-	-	-	-	-	-	-	-
KIOEMHBE_00594	2.13e-151	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
KIOEMHBE_00595	6.51e-247	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
KIOEMHBE_00596	1.43e-273	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	H	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KIOEMHBE_00597	0.0	tarL	2.7.8.14, 2.7.8.47	-	H	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KIOEMHBE_00598	4.87e-123	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
KIOEMHBE_00599	1.48e-98	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
KIOEMHBE_00600	0.0	gshR1	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
KIOEMHBE_00601	3.22e-87	-	-	-	-	-	-	-	-
KIOEMHBE_00602	4.49e-315	-	-	-	M	-	-	-	Glycosyl transferase family group 2
KIOEMHBE_00603	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KIOEMHBE_00604	3.59e-204	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
KIOEMHBE_00605	1.07e-43	-	-	-	S	-	-	-	YozE SAM-like fold
KIOEMHBE_00606	9.17e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KIOEMHBE_00607	3.8e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
KIOEMHBE_00608	3.21e-215	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
KIOEMHBE_00609	2.21e-227	-	-	-	K	-	-	-	Transcriptional regulator
KIOEMHBE_00610	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KIOEMHBE_00611	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KIOEMHBE_00612	2.4e-137	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KIOEMHBE_00613	3.64e-217	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
KIOEMHBE_00614	1.98e-239	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KIOEMHBE_00615	6.84e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KIOEMHBE_00616	1.5e-227	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
KIOEMHBE_00617	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KIOEMHBE_00618	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KIOEMHBE_00619	2.33e-202	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
KIOEMHBE_00620	8.64e-177	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KIOEMHBE_00621	2.25e-207	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KIOEMHBE_00623	5.99e-291	XK27_05470	-	-	E	-	-	-	Methionine synthase
KIOEMHBE_00624	1.73e-219	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
KIOEMHBE_00625	1.27e-222	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
KIOEMHBE_00626	3.53e-160	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
KIOEMHBE_00627	4.28e-253	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
KIOEMHBE_00628	2.44e-95	qacA	-	-	EGP	-	-	-	Major Facilitator
KIOEMHBE_00629	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
KIOEMHBE_00630	9.33e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
KIOEMHBE_00631	3.29e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
KIOEMHBE_00632	1.19e-208	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
KIOEMHBE_00633	2.03e-189	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
KIOEMHBE_00634	1.8e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KIOEMHBE_00635	6.7e-241	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KIOEMHBE_00636	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
KIOEMHBE_00637	6.46e-109	-	-	-	-	-	-	-	-
KIOEMHBE_00638	6.04e-290	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KIOEMHBE_00639	1.39e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KIOEMHBE_00640	1.29e-192	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
KIOEMHBE_00641	2.08e-284	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
KIOEMHBE_00642	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KIOEMHBE_00643	5.89e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
KIOEMHBE_00644	1.98e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
KIOEMHBE_00645	1.27e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
KIOEMHBE_00646	1.25e-39	-	-	-	M	-	-	-	Lysin motif
KIOEMHBE_00647	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
KIOEMHBE_00648	3.38e-252	-	-	-	S	-	-	-	Helix-turn-helix domain
KIOEMHBE_00649	2.24e-126	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KIOEMHBE_00650	2.69e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
KIOEMHBE_00651	1.3e-132	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KIOEMHBE_00652	7.1e-176	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KIOEMHBE_00653	3.99e-92	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KIOEMHBE_00654	3.13e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
KIOEMHBE_00655	4.59e-217	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
KIOEMHBE_00656	2.51e-98	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
KIOEMHBE_00657	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
KIOEMHBE_00658	8.69e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KIOEMHBE_00659	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
KIOEMHBE_00660	7.03e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
KIOEMHBE_00662	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KIOEMHBE_00663	1.29e-298	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
KIOEMHBE_00664	1.09e-249	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KIOEMHBE_00665	6.85e-164	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
KIOEMHBE_00666	1.75e-295	-	-	-	M	-	-	-	O-Antigen ligase
KIOEMHBE_00667	2.52e-165	drrB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
KIOEMHBE_00668	2.08e-213	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
KIOEMHBE_00669	2.74e-112	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
KIOEMHBE_00670	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
KIOEMHBE_00671	2.65e-81	-	-	-	P	-	-	-	Rhodanese Homology Domain
KIOEMHBE_00672	6.11e-118	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
KIOEMHBE_00673	1.93e-266	-	-	-	-	-	-	-	-
KIOEMHBE_00674	4.8e-278	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
KIOEMHBE_00675	1.68e-229	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
KIOEMHBE_00676	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
KIOEMHBE_00677	1.27e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KIOEMHBE_00678	4.6e-307	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
KIOEMHBE_00679	4.38e-102	-	-	-	K	-	-	-	Transcriptional regulator
KIOEMHBE_00680	1.3e-264	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
KIOEMHBE_00681	0.0	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
KIOEMHBE_00682	1.68e-176	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
KIOEMHBE_00683	1.4e-137	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
KIOEMHBE_00684	2.65e-93	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
KIOEMHBE_00685	6.34e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
KIOEMHBE_00686	8.09e-146	-	-	-	GM	-	-	-	epimerase
KIOEMHBE_00687	0.0	-	-	-	S	-	-	-	Zinc finger, swim domain protein
KIOEMHBE_00688	1.51e-105	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KIOEMHBE_00689	5.58e-274	-	-	-	S	-	-	-	membrane
KIOEMHBE_00690	2.15e-07	-	-	-	K	-	-	-	transcriptional regulator
KIOEMHBE_00691	7.17e-62	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KIOEMHBE_00692	3.2e-70	-	-	-	-	-	-	-	-
KIOEMHBE_00693	3.15e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KIOEMHBE_00694	1.57e-179	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
KIOEMHBE_00695	6.42e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KIOEMHBE_00696	9.99e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
KIOEMHBE_00697	1.6e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
KIOEMHBE_00698	7.69e-300	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KIOEMHBE_00699	1.46e-77	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KIOEMHBE_00700	2.85e-293	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KIOEMHBE_00701	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
KIOEMHBE_00702	4.49e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KIOEMHBE_00703	3.33e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KIOEMHBE_00704	2.17e-244	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KIOEMHBE_00705	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KIOEMHBE_00706	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
KIOEMHBE_00707	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
KIOEMHBE_00708	1.61e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
KIOEMHBE_00709	1.84e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
KIOEMHBE_00710	3.16e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
KIOEMHBE_00711	1.21e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KIOEMHBE_00712	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
KIOEMHBE_00713	1.62e-173	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
KIOEMHBE_00714	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KIOEMHBE_00715	1.01e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KIOEMHBE_00716	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KIOEMHBE_00717	1.28e-276	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KIOEMHBE_00718	3.93e-41	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KIOEMHBE_00719	6.96e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
KIOEMHBE_00720	8.28e-73	-	-	-	-	-	-	-	-
KIOEMHBE_00721	1.36e-136	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KIOEMHBE_00722	3.8e-224	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KIOEMHBE_00723	7.11e-135	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KIOEMHBE_00724	4.51e-284	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
KIOEMHBE_00725	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
KIOEMHBE_00726	2.15e-99	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
KIOEMHBE_00727	4.49e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
KIOEMHBE_00728	7.16e-201	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
KIOEMHBE_00729	7.55e-44	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KIOEMHBE_00730	3.28e-312	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KIOEMHBE_00731	4.82e-194	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KIOEMHBE_00732	2.82e-91	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KIOEMHBE_00733	1.7e-96	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
KIOEMHBE_00734	1.43e-129	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KIOEMHBE_00735	4.08e-247	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
KIOEMHBE_00736	2.33e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
KIOEMHBE_00737	7.97e-71	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
KIOEMHBE_00738	1.55e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
KIOEMHBE_00739	8.15e-125	-	-	-	K	-	-	-	Transcriptional regulator
KIOEMHBE_00740	9.81e-27	-	-	-	-	-	-	-	-
KIOEMHBE_00743	2.97e-41	-	-	-	-	-	-	-	-
KIOEMHBE_00744	3.11e-73	-	-	-	-	-	-	-	-
KIOEMHBE_00745	2.92e-126	-	-	-	S	-	-	-	Protein conserved in bacteria
KIOEMHBE_00746	1.34e-232	-	-	-	-	-	-	-	-
KIOEMHBE_00747	1.18e-205	-	-	-	-	-	-	-	-
KIOEMHBE_00748	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
KIOEMHBE_00749	7.79e-85	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
KIOEMHBE_00750	3.8e-224	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KIOEMHBE_00751	7.77e-179	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
KIOEMHBE_00752	1.44e-31	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
KIOEMHBE_00753	1.15e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
KIOEMHBE_00754	1.62e-141	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
KIOEMHBE_00755	2.6e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
KIOEMHBE_00756	6.33e-46	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
KIOEMHBE_00757	3.52e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
KIOEMHBE_00758	9.29e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KIOEMHBE_00759	5.33e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
KIOEMHBE_00760	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
KIOEMHBE_00761	0.0	-	-	-	S	-	-	-	membrane
KIOEMHBE_00762	6.12e-72	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
KIOEMHBE_00763	5.72e-99	-	-	-	K	-	-	-	LytTr DNA-binding domain
KIOEMHBE_00764	9.72e-146	-	-	-	S	-	-	-	membrane
KIOEMHBE_00765	1.09e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KIOEMHBE_00766	7.5e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
KIOEMHBE_00767	6.11e-249	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KIOEMHBE_00768	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KIOEMHBE_00769	6.88e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KIOEMHBE_00770	2.58e-82	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
KIOEMHBE_00771	1.72e-120	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
KIOEMHBE_00772	4.46e-179	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KIOEMHBE_00773	1.37e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
KIOEMHBE_00774	6.94e-209	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KIOEMHBE_00775	4.18e-121	-	-	-	S	-	-	-	SdpI/YhfL protein family
KIOEMHBE_00776	1.36e-288	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KIOEMHBE_00777	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
KIOEMHBE_00778	1.93e-218	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
KIOEMHBE_00779	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KIOEMHBE_00780	1.38e-155	csrR	-	-	K	-	-	-	response regulator
KIOEMHBE_00781	2.56e-310	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
KIOEMHBE_00782	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KIOEMHBE_00783	1.09e-223	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KIOEMHBE_00784	3.06e-124	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
KIOEMHBE_00785	3.66e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
KIOEMHBE_00786	3.04e-280	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
KIOEMHBE_00787	3.3e-180	yqeM	-	-	Q	-	-	-	Methyltransferase
KIOEMHBE_00788	1.06e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KIOEMHBE_00789	1.71e-149	yqeK	-	-	H	-	-	-	Hydrolase, HD family
KIOEMHBE_00790	4.19e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KIOEMHBE_00791	2.19e-67	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
KIOEMHBE_00792	3.81e-276	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
KIOEMHBE_00793	5.7e-127	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
KIOEMHBE_00794	6.32e-114	-	-	-	-	-	-	-	-
KIOEMHBE_00795	2.01e-289	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
KIOEMHBE_00796	3.97e-174	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
KIOEMHBE_00797	1.64e-83	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
KIOEMHBE_00798	1.18e-250	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
KIOEMHBE_00799	7.03e-307	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
KIOEMHBE_00800	4.59e-73	-	-	-	-	-	-	-	-
KIOEMHBE_00801	6.88e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KIOEMHBE_00802	6.92e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
KIOEMHBE_00803	2.37e-109	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KIOEMHBE_00804	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KIOEMHBE_00805	3.5e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
KIOEMHBE_00806	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
KIOEMHBE_00807	1.58e-117	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KIOEMHBE_00808	1.92e-133	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KIOEMHBE_00809	3.19e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KIOEMHBE_00810	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KIOEMHBE_00811	8.51e-155	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
KIOEMHBE_00812	1.04e-141	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
KIOEMHBE_00813	4.07e-60	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
KIOEMHBE_00814	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
KIOEMHBE_00815	2.71e-108	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
KIOEMHBE_00816	1.11e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KIOEMHBE_00817	5.21e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
KIOEMHBE_00818	1.1e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
KIOEMHBE_00819	2.87e-47	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
KIOEMHBE_00820	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
KIOEMHBE_00821	3.04e-29	-	-	-	S	-	-	-	Virus attachment protein p12 family
KIOEMHBE_00822	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
KIOEMHBE_00823	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
KIOEMHBE_00825	1.29e-148	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KIOEMHBE_00826	2.94e-71	ytzB	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
KIOEMHBE_00827	2.8e-155	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KIOEMHBE_00828	7.24e-197	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
KIOEMHBE_00829	8.17e-285	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
KIOEMHBE_00830	1.1e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KIOEMHBE_00831	3.6e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
KIOEMHBE_00832	6.76e-73	-	-	-	-	-	-	-	-
KIOEMHBE_00833	1.09e-196	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KIOEMHBE_00834	1.78e-153	draG	-	-	O	-	-	-	ADP-ribosylglycohydrolase
KIOEMHBE_00835	5.76e-135	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
KIOEMHBE_00836	2.82e-138	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
KIOEMHBE_00837	1.94e-247	-	-	-	S	-	-	-	Fn3-like domain
KIOEMHBE_00838	1.65e-80	-	-	-	-	-	-	-	-
KIOEMHBE_00839	0.0	-	-	-	-	-	-	-	-
KIOEMHBE_00840	4.26e-308	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
KIOEMHBE_00841	1.01e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
KIOEMHBE_00842	4.82e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
KIOEMHBE_00843	1.81e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KIOEMHBE_00844	5.41e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KIOEMHBE_00845	2.03e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KIOEMHBE_00846	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KIOEMHBE_00847	9.14e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KIOEMHBE_00848	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KIOEMHBE_00849	5.95e-74	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
KIOEMHBE_00850	4.85e-314	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KIOEMHBE_00851	1.68e-132	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
KIOEMHBE_00852	1.44e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
KIOEMHBE_00853	1.52e-57	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
KIOEMHBE_00854	1.04e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
KIOEMHBE_00855	2.15e-280	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
KIOEMHBE_00856	3.2e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
KIOEMHBE_00857	2.24e-239	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KIOEMHBE_00858	2.1e-151	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KIOEMHBE_00859	8.69e-191	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
KIOEMHBE_00860	3.34e-215	hicD3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
KIOEMHBE_00861	3.26e-227	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
KIOEMHBE_00862	7.55e-242	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
KIOEMHBE_00863	6.54e-273	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
KIOEMHBE_00864	0.0	glpQ3	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
KIOEMHBE_00865	4.7e-207	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KIOEMHBE_00866	1.1e-258	bla2	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
KIOEMHBE_00867	2.37e-107	uspA	-	-	T	-	-	-	universal stress protein
KIOEMHBE_00868	1.34e-52	-	-	-	-	-	-	-	-
KIOEMHBE_00869	7.27e-303	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
KIOEMHBE_00870	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
KIOEMHBE_00871	9.17e-59	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
KIOEMHBE_00872	1.24e-139	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
KIOEMHBE_00873	1.63e-104	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
KIOEMHBE_00874	4.02e-145	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
KIOEMHBE_00875	2.15e-137	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KIOEMHBE_00876	7.5e-105	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
KIOEMHBE_00877	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KIOEMHBE_00879	2.59e-277	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
KIOEMHBE_00880	8.93e-291	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KIOEMHBE_00881	1.57e-299	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
KIOEMHBE_00882	3.56e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KIOEMHBE_00883	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KIOEMHBE_00884	5.62e-316	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
KIOEMHBE_00885	1.15e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
KIOEMHBE_00886	1.74e-211	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
KIOEMHBE_00887	3.76e-184	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
KIOEMHBE_00888	9.47e-115	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
KIOEMHBE_00889	3.81e-150	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
KIOEMHBE_00890	1.23e-187	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
KIOEMHBE_00891	1.89e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
KIOEMHBE_00892	3.17e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KIOEMHBE_00893	2.61e-199	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
KIOEMHBE_00894	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
KIOEMHBE_00895	3.55e-296	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
KIOEMHBE_00896	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
KIOEMHBE_00897	5.74e-172	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
KIOEMHBE_00898	1.92e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KIOEMHBE_00899	3.83e-295	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
KIOEMHBE_00900	2.43e-264	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KIOEMHBE_00901	6.57e-291	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
KIOEMHBE_00902	6.18e-197	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
KIOEMHBE_00903	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KIOEMHBE_00904	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KIOEMHBE_00905	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
KIOEMHBE_00906	1.3e-91	-	-	-	-	-	-	-	-
KIOEMHBE_00907	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
KIOEMHBE_00908	4.02e-114	-	-	-	-	-	-	-	-
KIOEMHBE_00909	2.83e-138	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KIOEMHBE_00910	2.62e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KIOEMHBE_00911	5.87e-256	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KIOEMHBE_00912	9.91e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KIOEMHBE_00913	1.32e-63	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
KIOEMHBE_00914	2.48e-276	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KIOEMHBE_00915	8.32e-227	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
KIOEMHBE_00916	2.79e-316	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KIOEMHBE_00917	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KIOEMHBE_00918	5e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
KIOEMHBE_00919	5.39e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KIOEMHBE_00920	1.31e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
KIOEMHBE_00921	1.06e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KIOEMHBE_00922	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KIOEMHBE_00923	3e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
KIOEMHBE_00924	1.45e-161	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
KIOEMHBE_00925	5.06e-194	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
KIOEMHBE_00926	8.49e-144	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KIOEMHBE_00927	4.03e-125	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
KIOEMHBE_00928	7.94e-114	ykuL	-	-	S	-	-	-	(CBS) domain
KIOEMHBE_00929	2.29e-112	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KIOEMHBE_00930	6.72e-289	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KIOEMHBE_00931	2.31e-202	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
KIOEMHBE_00932	1.88e-75	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KIOEMHBE_00933	1.6e-96	-	-	-	-	-	-	-	-
KIOEMHBE_00934	9.86e-82	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
KIOEMHBE_00935	7.36e-274	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
KIOEMHBE_00936	5.44e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
KIOEMHBE_00937	3.21e-210	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
KIOEMHBE_00938	2.44e-65	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
KIOEMHBE_00939	2.21e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
KIOEMHBE_00940	2.06e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KIOEMHBE_00941	2.57e-224	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
KIOEMHBE_00942	6.2e-242	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
KIOEMHBE_00943	1.97e-72	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
KIOEMHBE_00944	1.5e-108	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
KIOEMHBE_00945	3.03e-27	-	-	-	-	ko:K02671	-	ko00000,ko02035,ko02044	-
KIOEMHBE_00946	6.46e-113	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
KIOEMHBE_00948	3.68e-235	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
KIOEMHBE_00949	4.7e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KIOEMHBE_00950	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
KIOEMHBE_00951	5.77e-151	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
KIOEMHBE_00952	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
KIOEMHBE_00953	1.96e-116	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
KIOEMHBE_00954	7.18e-189	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KIOEMHBE_00955	2.71e-150	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
KIOEMHBE_00956	8.38e-152	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
KIOEMHBE_00957	5.16e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KIOEMHBE_00958	2e-98	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	general stress protein
KIOEMHBE_00960	1.96e-293	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Cell cycle protein
KIOEMHBE_00961	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KIOEMHBE_00962	3.82e-184	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
KIOEMHBE_00963	4.46e-281	ywtF_2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
KIOEMHBE_00964	2.19e-131	-	-	-	L	-	-	-	Helix-turn-helix domain
KIOEMHBE_00965	1.14e-226	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family 2
KIOEMHBE_00966	3.81e-87	-	-	-	-	-	-	-	-
KIOEMHBE_00967	1.38e-98	-	-	-	-	-	-	-	-
KIOEMHBE_00968	1.56e-276	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
KIOEMHBE_00969	7.8e-123	-	-	-	-	-	-	-	-
KIOEMHBE_00970	7.22e-149	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KIOEMHBE_00971	7.68e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
KIOEMHBE_00972	3.96e-44	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
KIOEMHBE_00973	8.8e-155	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
KIOEMHBE_00974	2.11e-171	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
KIOEMHBE_00975	5.67e-64	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
KIOEMHBE_00976	1.92e-239	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KIOEMHBE_00977	2.92e-172	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
KIOEMHBE_00978	6.33e-185	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
KIOEMHBE_00979	1.88e-194	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KIOEMHBE_00980	3.01e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
KIOEMHBE_00981	9.83e-113	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KIOEMHBE_00982	3.17e-190	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KIOEMHBE_00983	1.13e-175	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
KIOEMHBE_00984	4.64e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
KIOEMHBE_00985	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KIOEMHBE_00986	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KIOEMHBE_00987	9.74e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
KIOEMHBE_00988	4.46e-275	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
KIOEMHBE_00989	2.95e-65	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
KIOEMHBE_00990	3.28e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
KIOEMHBE_00991	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KIOEMHBE_00992	3.04e-71	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KIOEMHBE_00993	0.0	-	-	-	G	-	-	-	Major Facilitator
KIOEMHBE_00994	3.67e-275	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KIOEMHBE_00995	1.63e-121	-	-	-	-	-	-	-	-
KIOEMHBE_00996	1.19e-285	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KIOEMHBE_00997	1.21e-245	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
KIOEMHBE_00998	2.41e-113	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KIOEMHBE_00999	8.94e-221	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KIOEMHBE_01000	2.53e-240	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
KIOEMHBE_01001	1.19e-169	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
KIOEMHBE_01002	4.42e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KIOEMHBE_01003	4.52e-111	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KIOEMHBE_01004	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
KIOEMHBE_01005	2.54e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KIOEMHBE_01006	8.49e-266	pbpX2	-	-	V	-	-	-	Beta-lactamase
KIOEMHBE_01007	8.59e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
KIOEMHBE_01008	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KIOEMHBE_01009	3.27e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
KIOEMHBE_01010	5.75e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KIOEMHBE_01011	1.68e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KIOEMHBE_01012	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KIOEMHBE_01013	1.01e-158	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
KIOEMHBE_01016	1.73e-67	-	-	-	-	-	-	-	-
KIOEMHBE_01017	4.78e-65	-	-	-	-	-	-	-	-
KIOEMHBE_01018	5.28e-146	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
KIOEMHBE_01019	2.04e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
KIOEMHBE_01020	3.13e-172	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KIOEMHBE_01021	2.56e-76	-	-	-	-	-	-	-	-
KIOEMHBE_01022	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KIOEMHBE_01023	8.2e-102	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KIOEMHBE_01024	2.43e-150	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
KIOEMHBE_01025	2.29e-207	-	-	-	G	-	-	-	Fructosamine kinase
KIOEMHBE_01026	4.01e-200	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
KIOEMHBE_01027	2.47e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
KIOEMHBE_01028	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KIOEMHBE_01029	2.61e-132	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KIOEMHBE_01030	4.35e-204	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KIOEMHBE_01031	1.84e-284	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KIOEMHBE_01032	1.42e-217	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KIOEMHBE_01033	1.78e-140	-	-	-	C	-	-	-	Enoyl-(Acyl carrier protein) reductase
KIOEMHBE_01034	2.32e-194	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KIOEMHBE_01035	1.09e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
KIOEMHBE_01036	9.21e-94	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
KIOEMHBE_01037	4.81e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
KIOEMHBE_01038	3.14e-109	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KIOEMHBE_01039	1.15e-94	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
KIOEMHBE_01040	7.92e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KIOEMHBE_01041	2.84e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
KIOEMHBE_01042	8.64e-224	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
KIOEMHBE_01043	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
KIOEMHBE_01044	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KIOEMHBE_01045	1.74e-251	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KIOEMHBE_01046	1.18e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
KIOEMHBE_01047	4.94e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KIOEMHBE_01048	5.23e-256	-	-	-	-	-	-	-	-
KIOEMHBE_01049	1.43e-251	-	-	-	-	-	-	-	-
KIOEMHBE_01050	6.05e-170	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
KIOEMHBE_01051	1.03e-206	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KIOEMHBE_01052	0.000138	yjdF	-	-	S	-	-	-	Protein of unknown function (DUF2992)
KIOEMHBE_01053	1.49e-147	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
KIOEMHBE_01054	2.25e-93	-	-	-	K	-	-	-	MarR family
KIOEMHBE_01055	6.64e-109	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
KIOEMHBE_01057	4.17e-204	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
KIOEMHBE_01058	1.27e-174	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
KIOEMHBE_01059	5.11e-266	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KIOEMHBE_01060	1.51e-132	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
KIOEMHBE_01061	0.0	nox4	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
KIOEMHBE_01063	3.78e-221	cryZ	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
KIOEMHBE_01064	5.72e-207	-	-	-	K	-	-	-	Transcriptional regulator
KIOEMHBE_01065	1.74e-101	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
KIOEMHBE_01066	1.39e-143	-	-	-	GM	-	-	-	NmrA-like family
KIOEMHBE_01067	8.81e-205	-	-	-	S	-	-	-	Alpha beta hydrolase
KIOEMHBE_01068	2.49e-167	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
KIOEMHBE_01069	2.31e-132	thgA3	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
KIOEMHBE_01070	7.21e-145	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
KIOEMHBE_01071	8.59e-85	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
KIOEMHBE_01072	1.13e-182	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
KIOEMHBE_01073	3.66e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
KIOEMHBE_01074	3.3e-202	degV1	-	-	S	-	-	-	DegV family
KIOEMHBE_01075	2.89e-80	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
KIOEMHBE_01076	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
KIOEMHBE_01078	2.76e-141	sip3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
KIOEMHBE_01079	0.0	-	-	-	-	-	-	-	-
KIOEMHBE_01081	2.13e-209	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
KIOEMHBE_01082	2.16e-142	-	-	-	S	-	-	-	Cell surface protein
KIOEMHBE_01083	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KIOEMHBE_01084	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KIOEMHBE_01085	2.14e-155	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
KIOEMHBE_01086	3.75e-305	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
KIOEMHBE_01087	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
KIOEMHBE_01088	1.55e-158	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KIOEMHBE_01089	3.74e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KIOEMHBE_01090	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KIOEMHBE_01091	8.19e-267	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KIOEMHBE_01092	3.82e-51	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
KIOEMHBE_01093	7.24e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KIOEMHBE_01094	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KIOEMHBE_01095	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KIOEMHBE_01096	5.95e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
KIOEMHBE_01097	1.59e-95	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KIOEMHBE_01098	2.69e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KIOEMHBE_01099	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
KIOEMHBE_01100	3.44e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
KIOEMHBE_01101	8.77e-317	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
KIOEMHBE_01102	4.96e-289	yttB	-	-	EGP	-	-	-	Major Facilitator
KIOEMHBE_01103	9e-184	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KIOEMHBE_01104	2.19e-290	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KIOEMHBE_01106	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
KIOEMHBE_01107	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KIOEMHBE_01108	6.65e-282	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KIOEMHBE_01109	3.49e-269	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
KIOEMHBE_01110	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
KIOEMHBE_01111	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KIOEMHBE_01112	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
KIOEMHBE_01113	8.38e-184	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
KIOEMHBE_01114	1.1e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
KIOEMHBE_01115	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
KIOEMHBE_01116	3.21e-104	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
KIOEMHBE_01117	4.37e-43	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein domain
KIOEMHBE_01118	2.54e-50	-	-	-	-	-	-	-	-
KIOEMHBE_01120	2.22e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
KIOEMHBE_01121	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KIOEMHBE_01122	3.55e-313	yycH	-	-	S	-	-	-	YycH protein
KIOEMHBE_01123	3.54e-195	yycI	-	-	S	-	-	-	YycH protein
KIOEMHBE_01124	1.71e-200	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
KIOEMHBE_01125	1.5e-253	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
KIOEMHBE_01126	6.08e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KIOEMHBE_01127	3.46e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KIOEMHBE_01128	0.0	-	-	-	C	-	-	-	Belongs to the aldehyde dehydrogenase family
KIOEMHBE_01129	6.96e-214	-	-	-	L	-	-	-	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
KIOEMHBE_01130	5.97e-157	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
KIOEMHBE_01131	4.75e-42	pnb	-	-	C	-	-	-	nitroreductase
KIOEMHBE_01132	5.63e-86	pnb	-	-	C	-	-	-	nitroreductase
KIOEMHBE_01133	4.95e-86	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
KIOEMHBE_01134	1.57e-150	-	-	-	S	-	-	-	Elongation factor G-binding protein, N-terminal
KIOEMHBE_01135	0.0	-	-	-	C	-	-	-	FMN_bind
KIOEMHBE_01136	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
KIOEMHBE_01137	1.46e-204	-	-	-	K	-	-	-	LysR family
KIOEMHBE_01138	2.49e-95	-	-	-	C	-	-	-	FMN binding
KIOEMHBE_01139	4.48e-98	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KIOEMHBE_01140	4.06e-211	-	-	-	S	-	-	-	KR domain
KIOEMHBE_01141	5.74e-204	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
KIOEMHBE_01142	5.07e-157	ydgI	-	-	C	-	-	-	Nitroreductase family
KIOEMHBE_01143	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
KIOEMHBE_01144	1.56e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
KIOEMHBE_01145	7.63e-249	pva1	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KIOEMHBE_01146	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
KIOEMHBE_01147	6.86e-175	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
KIOEMHBE_01148	0.0	hpaH	1.14.14.8, 1.14.14.9	-	Q	ko:K00483,ko:K16901	ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220	ko00000,ko00001,ko01000	4-hydroxyphenylacetate
KIOEMHBE_01149	1.65e-106	-	-	-	S	-	-	-	ASCH
KIOEMHBE_01150	1.25e-164	-	-	-	F	-	-	-	glutamine amidotransferase
KIOEMHBE_01151	1.67e-220	-	-	-	K	-	-	-	WYL domain
KIOEMHBE_01152	1.63e-152	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KIOEMHBE_01153	0.0	fusA1	-	-	J	-	-	-	elongation factor G
KIOEMHBE_01154	7.44e-51	-	-	-	S	-	-	-	Protein of unknown function
KIOEMHBE_01155	2.7e-79	-	-	-	S	-	-	-	Protein of unknown function
KIOEMHBE_01156	8.64e-195	-	-	-	EG	-	-	-	EamA-like transporter family
KIOEMHBE_01157	7.65e-121	yfbM	-	-	K	-	-	-	FR47-like protein
KIOEMHBE_01158	1.4e-162	-	-	-	S	-	-	-	DJ-1/PfpI family
KIOEMHBE_01159	3.14e-230	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
KIOEMHBE_01160	1.92e-67	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
KIOEMHBE_01161	5.98e-302	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
KIOEMHBE_01162	1.66e-101	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
KIOEMHBE_01163	3.46e-267	mccF	-	-	V	-	-	-	LD-carboxypeptidase
KIOEMHBE_01164	9.63e-307	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
KIOEMHBE_01165	9.19e-95	-	-	-	S	-	-	-	SnoaL-like domain
KIOEMHBE_01166	4.17e-186	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
KIOEMHBE_01167	1.55e-309	-	-	-	P	-	-	-	Major Facilitator Superfamily
KIOEMHBE_01168	1.26e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
KIOEMHBE_01169	1.44e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
KIOEMHBE_01171	9.98e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KIOEMHBE_01172	2.12e-142	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
KIOEMHBE_01173	3.6e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KIOEMHBE_01174	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
KIOEMHBE_01175	4.64e-228	phnT	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
KIOEMHBE_01176	8.06e-234	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
KIOEMHBE_01177	0.0	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KIOEMHBE_01178	5.32e-109	-	-	-	T	-	-	-	Universal stress protein family
KIOEMHBE_01179	1.58e-203	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
KIOEMHBE_01180	2.45e-142	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KIOEMHBE_01181	2.32e-238	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KIOEMHBE_01183	9.32e-165	dnaD	-	-	L	ko:K02086	-	ko00000	Replication initiation and membrane attachment
KIOEMHBE_01184	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
KIOEMHBE_01185	3.1e-289	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
KIOEMHBE_01186	2.53e-107	ypmB	-	-	S	-	-	-	protein conserved in bacteria
KIOEMHBE_01187	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
KIOEMHBE_01188	1.48e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
KIOEMHBE_01189	1.1e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
KIOEMHBE_01190	2.94e-261	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
KIOEMHBE_01191	8.61e-251	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KIOEMHBE_01192	3.36e-247	galM2	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
KIOEMHBE_01193	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
KIOEMHBE_01194	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
KIOEMHBE_01195	3.24e-155	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
KIOEMHBE_01196	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
KIOEMHBE_01197	3.86e-192	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
KIOEMHBE_01198	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
KIOEMHBE_01199	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KIOEMHBE_01200	1.54e-56	-	-	-	-	-	-	-	-
KIOEMHBE_01201	1.25e-66	-	-	-	-	-	-	-	-
KIOEMHBE_01202	5.03e-182	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
KIOEMHBE_01203	1.48e-218	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
KIOEMHBE_01204	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KIOEMHBE_01205	8.39e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
KIOEMHBE_01206	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
KIOEMHBE_01207	1.06e-53	-	-	-	-	-	-	-	-
KIOEMHBE_01208	4e-40	-	-	-	S	-	-	-	CsbD-like
KIOEMHBE_01209	2.22e-55	-	-	-	S	-	-	-	transglycosylase associated protein
KIOEMHBE_01210	5.79e-21	-	-	-	-	-	-	-	-
KIOEMHBE_01211	8.76e-48	-	-	-	-	-	-	-	-
KIOEMHBE_01212	1.21e-209	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
KIOEMHBE_01213	5.58e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
KIOEMHBE_01214	5.28e-100	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
KIOEMHBE_01215	6.05e-108	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
KIOEMHBE_01216	2.05e-55	-	-	-	-	-	-	-	-
KIOEMHBE_01217	5.93e-60	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
KIOEMHBE_01218	9.96e-147	-	1.14.99.53	AA10	S	ko:K21713	-	ko00000,ko01000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
KIOEMHBE_01219	3.2e-37	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
KIOEMHBE_01220	6.57e-274	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
KIOEMHBE_01221	2.02e-39	-	-	-	-	-	-	-	-
KIOEMHBE_01222	1.48e-71	-	-	-	-	-	-	-	-
KIOEMHBE_01223	1.14e-193	-	-	-	O	-	-	-	Band 7 protein
KIOEMHBE_01224	0.0	-	-	-	EGP	-	-	-	Major Facilitator
KIOEMHBE_01225	4.09e-119	-	-	-	K	-	-	-	transcriptional regulator
KIOEMHBE_01226	4.4e-246	rsgA_2	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KIOEMHBE_01227	2.01e-113	ykhA	-	-	I	-	-	-	Thioesterase superfamily
KIOEMHBE_01228	7.52e-207	-	-	-	K	-	-	-	LysR substrate binding domain
KIOEMHBE_01229	1.48e-161	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
KIOEMHBE_01230	5.01e-129	-	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
KIOEMHBE_01231	2.29e-175	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
KIOEMHBE_01232	4.82e-179	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
KIOEMHBE_01233	6.43e-203	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KIOEMHBE_01234	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
KIOEMHBE_01235	1.71e-91	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
KIOEMHBE_01236	2.14e-95	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KIOEMHBE_01237	1.8e-288	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KIOEMHBE_01238	1.26e-162	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
KIOEMHBE_01239	3.47e-215	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
KIOEMHBE_01240	6.16e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KIOEMHBE_01241	1.62e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KIOEMHBE_01242	8.55e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KIOEMHBE_01243	1.62e-229	yneE	-	-	K	-	-	-	Transcriptional regulator
KIOEMHBE_01244	6.84e-186	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
KIOEMHBE_01246	1.49e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
KIOEMHBE_01247	2.69e-252	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
KIOEMHBE_01248	3.38e-274	hipO1	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	Peptidase family M20/M25/M40
KIOEMHBE_01249	1.62e-276	-	-	-	E	-	-	-	glutamate:sodium symporter activity
KIOEMHBE_01250	1.95e-88	ybbJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
KIOEMHBE_01251	1.36e-210	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
KIOEMHBE_01252	5.89e-126	entB	-	-	Q	-	-	-	Isochorismatase family
KIOEMHBE_01253	4.82e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KIOEMHBE_01254	5.13e-287	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KIOEMHBE_01255	1.57e-142	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
KIOEMHBE_01256	2.41e-165	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
KIOEMHBE_01257	6.03e-226	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KIOEMHBE_01258	8.08e-135	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
KIOEMHBE_01259	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
KIOEMHBE_01261	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
KIOEMHBE_01262	2.05e-179	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
KIOEMHBE_01263	9.06e-112	-	-	-	-	-	-	-	-
KIOEMHBE_01264	2.81e-194	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
KIOEMHBE_01265	7.81e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KIOEMHBE_01266	3.04e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KIOEMHBE_01267	1.79e-243	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KIOEMHBE_01268	3.44e-204	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KIOEMHBE_01269	1.88e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KIOEMHBE_01270	1.54e-141	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
KIOEMHBE_01271	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
KIOEMHBE_01272	3.04e-174	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
KIOEMHBE_01273	4.07e-249	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
KIOEMHBE_01274	3.76e-245	ampC	-	-	V	-	-	-	Beta-lactamase
KIOEMHBE_01275	8.57e-41	-	-	-	-	-	-	-	-
KIOEMHBE_01276	1.9e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
KIOEMHBE_01277	1.33e-77	-	-	-	-	-	-	-	-
KIOEMHBE_01278	1.08e-181	-	-	-	-	-	-	-	-
KIOEMHBE_01279	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
KIOEMHBE_01280	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
KIOEMHBE_01281	1.81e-85	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
KIOEMHBE_01282	2.91e-177	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
KIOEMHBE_01284	2.93e-73	-	-	-	V	-	-	-	Abortive infection bacteriophage resistance protein
KIOEMHBE_01285	5.11e-59	-	-	-	S	-	-	-	Bacteriophage holin
KIOEMHBE_01286	8.04e-245	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
KIOEMHBE_01288	1.4e-27	-	-	-	-	-	-	-	-
KIOEMHBE_01289	1.4e-108	-	-	-	-	-	-	-	-
KIOEMHBE_01293	8.28e-127	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
KIOEMHBE_01294	2.64e-220	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
KIOEMHBE_01295	0.0	-	-	-	M	-	-	-	Prophage endopeptidase tail
KIOEMHBE_01296	9.72e-173	-	-	-	S	-	-	-	phage tail
KIOEMHBE_01297	0.0	-	-	-	D	-	-	-	domain protein
KIOEMHBE_01299	5.37e-107	-	-	-	S	-	-	-	Phage tail assembly chaperone protein, TAC
KIOEMHBE_01300	2.09e-123	-	-	-	-	-	-	-	-
KIOEMHBE_01301	5.59e-81	-	-	-	-	-	-	-	-
KIOEMHBE_01302	9.66e-123	-	-	-	-	-	-	-	-
KIOEMHBE_01303	5.46e-67	-	-	-	-	-	-	-	-
KIOEMHBE_01304	3.11e-75	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
KIOEMHBE_01305	2.45e-247	gpG	-	-	-	-	-	-	-
KIOEMHBE_01306	2.66e-110	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
KIOEMHBE_01307	5.76e-216	-	-	-	S	-	-	-	Phage Mu protein F like protein
KIOEMHBE_01308	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
KIOEMHBE_01309	2.91e-316	-	-	-	S	ko:K06909	-	ko00000	Phage terminase, large subunit
KIOEMHBE_01311	3.13e-98	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
KIOEMHBE_01314	7.56e-25	-	-	-	-	-	-	-	-
KIOEMHBE_01315	1.15e-40	-	-	-	S	-	-	-	ASCH
KIOEMHBE_01316	2.49e-97	-	-	-	K	-	-	-	acetyltransferase
KIOEMHBE_01321	3.54e-18	-	-	-	S	-	-	-	YopX protein
KIOEMHBE_01323	3.68e-82	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
KIOEMHBE_01324	3.24e-67	-	-	-	-	-	-	-	-
KIOEMHBE_01325	7.28e-213	-	-	-	L	-	-	-	DnaD domain protein
KIOEMHBE_01326	6.45e-80	-	-	-	-	-	-	-	-
KIOEMHBE_01327	8e-70	-	-	-	S	-	-	-	Bacteriophage Mu Gam like protein
KIOEMHBE_01329	2.15e-110	-	-	-	-	-	-	-	-
KIOEMHBE_01330	6.59e-72	-	-	-	-	-	-	-	-
KIOEMHBE_01332	7.19e-51	-	-	-	K	-	-	-	Helix-turn-helix
KIOEMHBE_01333	2.67e-80	-	-	-	K	-	-	-	Helix-turn-helix domain
KIOEMHBE_01334	1.92e-97	-	-	-	E	-	-	-	IrrE N-terminal-like domain
KIOEMHBE_01335	2.69e-38	-	-	-	S	-	-	-	TerB N-terminal domain
KIOEMHBE_01337	4.23e-19	-	-	-	S	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
KIOEMHBE_01341	9.38e-279	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
KIOEMHBE_01343	1.98e-40	-	-	-	-	-	-	-	-
KIOEMHBE_01346	1.02e-80	-	-	-	-	-	-	-	-
KIOEMHBE_01347	1.75e-48	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
KIOEMHBE_01348	0.0	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
KIOEMHBE_01349	6.16e-260	-	-	-	S	-	-	-	Phage portal protein
KIOEMHBE_01351	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
KIOEMHBE_01352	1.9e-109	terS	-	-	L	-	-	-	Phage terminase, small subunit
KIOEMHBE_01353	1.05e-88	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	Phage-associated protein
KIOEMHBE_01354	3.24e-62	-	-	-	S	-	-	-	Head-tail joining protein
KIOEMHBE_01356	3.36e-96	-	-	-	-	-	-	-	-
KIOEMHBE_01357	0.0	-	-	-	S	-	-	-	Virulence-associated protein E
KIOEMHBE_01358	1.5e-187	-	-	-	L	-	-	-	DNA replication protein
KIOEMHBE_01359	2.62e-40	-	-	-	-	-	-	-	-
KIOEMHBE_01362	1.1e-06	-	-	-	K	ko:K07727	-	ko00000,ko03000	transcriptional regulator
KIOEMHBE_01363	1.79e-289	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
KIOEMHBE_01364	1.28e-51	-	-	-	-	-	-	-	-
KIOEMHBE_01365	9.28e-58	-	-	-	-	-	-	-	-
KIOEMHBE_01366	1.27e-109	-	-	-	K	-	-	-	MarR family
KIOEMHBE_01367	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
KIOEMHBE_01368	2.55e-217	inlJ	-	-	M	-	-	-	MucBP domain
KIOEMHBE_01369	9.05e-22	-	-	-	-	-	-	-	-
KIOEMHBE_01370	2.69e-23	-	-	-	-	-	-	-	-
KIOEMHBE_01371	9.85e-22	-	-	-	-	-	-	-	-
KIOEMHBE_01372	6.21e-26	-	-	-	-	-	-	-	-
KIOEMHBE_01373	6.21e-26	-	-	-	-	-	-	-	-
KIOEMHBE_01374	1.25e-25	-	-	-	-	-	-	-	-
KIOEMHBE_01375	4.63e-24	-	-	-	-	-	-	-	-
KIOEMHBE_01376	0.0	-	3.6.3.44	-	P	ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
KIOEMHBE_01377	2.62e-76	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
KIOEMHBE_01378	1.89e-254	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
KIOEMHBE_01379	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KIOEMHBE_01380	2.1e-33	-	-	-	-	-	-	-	-
KIOEMHBE_01381	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
KIOEMHBE_01382	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KIOEMHBE_01383	1.56e-46	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
KIOEMHBE_01384	3.91e-289	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
KIOEMHBE_01385	2.29e-292	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
KIOEMHBE_01386	2.16e-241	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KIOEMHBE_01387	2.04e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
KIOEMHBE_01388	1.41e-285	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
KIOEMHBE_01389	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KIOEMHBE_01390	1.24e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
KIOEMHBE_01391	5.6e-41	-	-	-	-	-	-	-	-
KIOEMHBE_01392	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
KIOEMHBE_01393	3.29e-95	-	-	-	L	-	-	-	Integrase
KIOEMHBE_01394	3.4e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
KIOEMHBE_01395	5.67e-231	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KIOEMHBE_01396	4.86e-258	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KIOEMHBE_01397	3.59e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIOEMHBE_01398	3.44e-210	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIOEMHBE_01399	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
KIOEMHBE_01400	3.85e-76	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
KIOEMHBE_01401	1.01e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
KIOEMHBE_01402	1.36e-208	lysR5	-	-	K	-	-	-	LysR substrate binding domain
KIOEMHBE_01403	1.01e-250	-	-	-	M	-	-	-	MucBP domain
KIOEMHBE_01404	0.0	-	-	-	-	-	-	-	-
KIOEMHBE_01405	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KIOEMHBE_01406	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
KIOEMHBE_01407	1.22e-218	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
KIOEMHBE_01408	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
KIOEMHBE_01409	7.89e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
KIOEMHBE_01410	6.04e-94	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
KIOEMHBE_01411	1.13e-257	yueF	-	-	S	-	-	-	AI-2E family transporter
KIOEMHBE_01412	7.3e-216	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
KIOEMHBE_01413	7.17e-39	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
KIOEMHBE_01414	3.97e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
KIOEMHBE_01415	1.94e-170	lytE	-	-	M	-	-	-	NlpC/P60 family
KIOEMHBE_01416	6.62e-138	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
KIOEMHBE_01417	1.01e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
KIOEMHBE_01418	1.34e-168	-	-	-	-	-	-	-	-
KIOEMHBE_01419	1.68e-131	-	-	-	K	-	-	-	DNA-templated transcription, initiation
KIOEMHBE_01420	3.31e-35	-	-	-	-	-	-	-	-
KIOEMHBE_01421	1.95e-41	-	-	-	-	-	-	-	-
KIOEMHBE_01422	1.04e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
KIOEMHBE_01423	9.02e-70	-	-	-	-	-	-	-	-
KIOEMHBE_01425	3.98e-169	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
KIOEMHBE_01426	1.95e-197	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
KIOEMHBE_01427	3.34e-267	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KIOEMHBE_01428	3.3e-281	pbpX	-	-	V	-	-	-	Beta-lactamase
KIOEMHBE_01429	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
KIOEMHBE_01430	8.31e-139	-	-	-	-	-	-	-	-
KIOEMHBE_01431	7.62e-97	-	-	-	-	-	-	-	-
KIOEMHBE_01433	3.21e-209	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KIOEMHBE_01434	3.15e-313	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KIOEMHBE_01435	3.93e-99	-	-	-	T	-	-	-	Universal stress protein family
KIOEMHBE_01437	5.62e-316	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
KIOEMHBE_01438	7.89e-245	mocA	-	-	S	-	-	-	Oxidoreductase
KIOEMHBE_01439	6.22e-43	cspP	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
KIOEMHBE_01440	7.34e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
KIOEMHBE_01441	2.22e-185	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
KIOEMHBE_01442	5.63e-196	gntR	-	-	K	-	-	-	rpiR family
KIOEMHBE_01443	2.87e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KIOEMHBE_01444	7.06e-307	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KIOEMHBE_01445	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
KIOEMHBE_01446	2.26e-129	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KIOEMHBE_01447	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KIOEMHBE_01448	1.59e-242	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
KIOEMHBE_01449	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KIOEMHBE_01450	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KIOEMHBE_01451	5.11e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KIOEMHBE_01452	9.48e-263	camS	-	-	S	-	-	-	sex pheromone
KIOEMHBE_01453	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KIOEMHBE_01454	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
KIOEMHBE_01455	1.39e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KIOEMHBE_01456	1.13e-120	yebE	-	-	S	-	-	-	UPF0316 protein
KIOEMHBE_01457	2.01e-134	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KIOEMHBE_01458	1.97e-145	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
KIOEMHBE_01459	7.78e-235	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
KIOEMHBE_01460	5.44e-159	-	-	-	T	-	-	-	EAL domain
KIOEMHBE_01461	8.04e-190	-	3.1.3.23	-	S	ko:K07757	-	ko00000,ko01000	Sucrose-6F-phosphate phosphohydrolase
KIOEMHBE_01462	1.21e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KIOEMHBE_01463	1.46e-263	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
KIOEMHBE_01464	3.38e-70	-	-	-	-	-	-	-	-
KIOEMHBE_01465	2.49e-95	-	-	-	-	-	-	-	-
KIOEMHBE_01466	2.87e-168	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
KIOEMHBE_01467	7.08e-197	-	-	-	G	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
KIOEMHBE_01468	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KIOEMHBE_01469	6.37e-186	-	-	-	-	-	-	-	-
KIOEMHBE_01471	5.45e-94	spx1	-	-	P	ko:K16509	-	ko00000	ArsC family
KIOEMHBE_01472	3.88e-46	-	-	-	-	-	-	-	-
KIOEMHBE_01473	1.71e-116	-	-	-	V	-	-	-	VanZ like family
KIOEMHBE_01474	3.49e-315	-	-	-	EGP	-	-	-	Major Facilitator
KIOEMHBE_01475	4.45e-226	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
KIOEMHBE_01476	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KIOEMHBE_01477	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
KIOEMHBE_01478	7.8e-196	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
KIOEMHBE_01479	3.68e-107	-	-	-	K	-	-	-	Transcriptional regulator
KIOEMHBE_01480	1.36e-27	-	-	-	-	-	-	-	-
KIOEMHBE_01481	1.79e-287	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
KIOEMHBE_01482	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
KIOEMHBE_01483	5.47e-198	ribC1	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
KIOEMHBE_01484	0.0	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
KIOEMHBE_01485	3.45e-231	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
KIOEMHBE_01486	5.01e-229	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KIOEMHBE_01487	0.0	oatA	-	-	I	-	-	-	Acyltransferase
KIOEMHBE_01488	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KIOEMHBE_01489	1.55e-89	-	-	-	O	-	-	-	OsmC-like protein
KIOEMHBE_01490	3.8e-61	-	-	-	-	-	-	-	-
KIOEMHBE_01491	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
KIOEMHBE_01492	6.12e-115	-	-	-	-	-	-	-	-
KIOEMHBE_01493	1.23e-189	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
KIOEMHBE_01494	7.48e-96	-	-	-	F	-	-	-	Nudix hydrolase
KIOEMHBE_01495	1.48e-27	-	-	-	-	-	-	-	-
KIOEMHBE_01496	2.45e-134	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
KIOEMHBE_01497	2.02e-106	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
KIOEMHBE_01498	8.84e-18	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
KIOEMHBE_01499	1.01e-188	-	-	-	-	-	-	-	-
KIOEMHBE_01500	1.94e-95	gph1	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant
KIOEMHBE_01501	1.05e-234	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
KIOEMHBE_01502	2.07e-217	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KIOEMHBE_01503	1.28e-54	-	-	-	-	-	-	-	-
KIOEMHBE_01505	2.3e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KIOEMHBE_01506	3.39e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
KIOEMHBE_01507	3.14e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KIOEMHBE_01508	1.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KIOEMHBE_01509	7.04e-108	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KIOEMHBE_01510	7.77e-197	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
KIOEMHBE_01511	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
KIOEMHBE_01512	4.87e-180	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
KIOEMHBE_01513	9.38e-317	steT	-	-	E	ko:K03294	-	ko00000	amino acid
KIOEMHBE_01514	6.26e-96	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
KIOEMHBE_01515	8.87e-191	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
KIOEMHBE_01516	7.26e-92	-	-	-	K	-	-	-	MarR family
KIOEMHBE_01517	3.22e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
KIOEMHBE_01518	2.93e-109	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
KIOEMHBE_01519	1.81e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KIOEMHBE_01520	5.95e-300	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KIOEMHBE_01521	4.6e-102	rppH3	-	-	F	-	-	-	NUDIX domain
KIOEMHBE_01522	3.5e-64	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
KIOEMHBE_01523	1.61e-36	-	-	-	-	-	-	-	-
KIOEMHBE_01524	1.35e-165	pgm3	-	-	G	-	-	-	Phosphoglycerate mutase family
KIOEMHBE_01525	2.07e-161	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
KIOEMHBE_01526	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
KIOEMHBE_01527	4.16e-227	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
KIOEMHBE_01528	4.51e-143	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
KIOEMHBE_01529	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
KIOEMHBE_01530	8.45e-211	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
KIOEMHBE_01531	1.22e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
KIOEMHBE_01532	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
KIOEMHBE_01534	3.56e-171	spoVK	-	-	O	ko:K06413	-	ko00000	ATPase family associated with various cellular activities (AAA)
KIOEMHBE_01536	9.16e-61	-	-	-	L	-	-	-	Helix-turn-helix domain
KIOEMHBE_01537	8.56e-38	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
KIOEMHBE_01538	6.67e-30	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
KIOEMHBE_01539	1.66e-96	-	-	-	-	-	-	-	-
KIOEMHBE_01540	1.08e-71	-	-	-	-	-	-	-	-
KIOEMHBE_01541	1.37e-83	-	-	-	K	-	-	-	Helix-turn-helix domain
KIOEMHBE_01551	3.26e-119	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
KIOEMHBE_01552	6.36e-237	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
KIOEMHBE_01553	1.25e-124	-	-	-	-	-	-	-	-
KIOEMHBE_01554	1.58e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
KIOEMHBE_01555	2.98e-46	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
KIOEMHBE_01556	3.47e-134	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
KIOEMHBE_01558	2.19e-291	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
KIOEMHBE_01559	6.21e-241	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
KIOEMHBE_01560	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
KIOEMHBE_01561	2.75e-216	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
KIOEMHBE_01562	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
KIOEMHBE_01563	3.35e-157	-	-	-	-	-	-	-	-
KIOEMHBE_01564	2.78e-273	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KIOEMHBE_01565	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
KIOEMHBE_01566	1.37e-60	-	-	-	N	-	-	-	Cell shape-determining protein MreB
KIOEMHBE_01567	1.21e-185	-	-	-	N	-	-	-	Cell shape-determining protein MreB
KIOEMHBE_01568	0.0	-	-	-	S	-	-	-	Pfam Methyltransferase
KIOEMHBE_01569	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
KIOEMHBE_01570	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
KIOEMHBE_01571	9.32e-40	-	-	-	-	-	-	-	-
KIOEMHBE_01572	3.03e-122	mraW1	-	-	J	-	-	-	Putative rRNA methylase
KIOEMHBE_01573	3.58e-161	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
KIOEMHBE_01574	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
KIOEMHBE_01575	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
KIOEMHBE_01576	5.04e-176	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
KIOEMHBE_01577	3.03e-193	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KIOEMHBE_01578	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
KIOEMHBE_01579	2.16e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
KIOEMHBE_01580	2.92e-258	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
KIOEMHBE_01581	1.13e-221	ugpA	-	-	U	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KIOEMHBE_01582	3.05e-193	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KIOEMHBE_01583	5.01e-229	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
KIOEMHBE_01584	2.07e-155	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
KIOEMHBE_01585	3.55e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KIOEMHBE_01586	3e-315	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
KIOEMHBE_01588	3.34e-160	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
KIOEMHBE_01589	3.06e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
KIOEMHBE_01590	2.57e-226	-	-	-	K	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
KIOEMHBE_01592	6.96e-198	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KIOEMHBE_01593	5.2e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
KIOEMHBE_01594	1.64e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
KIOEMHBE_01595	9.36e-205	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KIOEMHBE_01596	1.89e-189	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
KIOEMHBE_01597	7.83e-140	-	-	-	-	-	-	-	-
KIOEMHBE_01598	2.08e-283	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
KIOEMHBE_01599	9.01e-179	agrA	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
KIOEMHBE_01600	5.37e-74	-	-	-	-	-	-	-	-
KIOEMHBE_01601	4.56e-78	-	-	-	-	-	-	-	-
KIOEMHBE_01602	1.23e-145	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
KIOEMHBE_01603	2.2e-111	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
KIOEMHBE_01604	8.82e-119	-	-	-	-	-	-	-	-
KIOEMHBE_01605	7.12e-62	-	-	-	-	-	-	-	-
KIOEMHBE_01606	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
KIOEMHBE_01608	4.29e-87	-	-	-	-	-	-	-	-
KIOEMHBE_01609	9.03e-16	-	-	-	-	-	-	-	-
KIOEMHBE_01610	3.89e-237	-	-	-	-	-	-	-	-
KIOEMHBE_01611	4.91e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
KIOEMHBE_01612	8.01e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
KIOEMHBE_01613	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
KIOEMHBE_01614	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KIOEMHBE_01615	0.0	-	-	-	S	-	-	-	Protein conserved in bacteria
KIOEMHBE_01616	7.32e-292	sat	2.7.7.4	-	H	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
KIOEMHBE_01617	3.72e-145	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
KIOEMHBE_01618	2.54e-225	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
KIOEMHBE_01619	0.0	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
KIOEMHBE_01620	0.0	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
KIOEMHBE_01621	4.75e-157	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
KIOEMHBE_01622	1.13e-171	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
KIOEMHBE_01623	4.87e-156	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
KIOEMHBE_01624	4.32e-294	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
KIOEMHBE_01625	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
KIOEMHBE_01626	1.96e-137	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
KIOEMHBE_01627	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
KIOEMHBE_01628	1.17e-135	-	-	-	K	-	-	-	transcriptional regulator
KIOEMHBE_01629	2.04e-158	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
KIOEMHBE_01630	1.49e-63	-	-	-	-	-	-	-	-
KIOEMHBE_01631	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
KIOEMHBE_01632	5.06e-236	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
KIOEMHBE_01633	2.87e-56	-	-	-	-	-	-	-	-
KIOEMHBE_01634	1.6e-73	-	-	-	-	-	-	-	-
KIOEMHBE_01635	6.86e-311	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KIOEMHBE_01636	2.78e-167	yidA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
KIOEMHBE_01637	9.86e-65	-	-	-	-	-	-	-	-
KIOEMHBE_01638	2.58e-163	rrp2	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
KIOEMHBE_01639	1.72e-315	hpk2	-	-	T	-	-	-	Histidine kinase
KIOEMHBE_01640	2.2e-86	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
KIOEMHBE_01641	0.0	ydiC	-	-	EGP	-	-	-	Major Facilitator
KIOEMHBE_01642	3.13e-55	-	-	-	-	-	-	-	-
KIOEMHBE_01643	6.37e-52	-	-	-	-	-	-	-	-
KIOEMHBE_01644	4.5e-150	-	-	-	-	-	-	-	-
KIOEMHBE_01645	4.02e-301	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
KIOEMHBE_01646	8.62e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KIOEMHBE_01647	8.9e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
KIOEMHBE_01648	2.73e-92	-	-	-	-	-	-	-	-
KIOEMHBE_01649	3.37e-129	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
KIOEMHBE_01650	0.0	tagF2	2.7.8.12	-	H	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KIOEMHBE_01651	5.71e-306	tagB	2.7.8.12, 2.7.8.45	-	M	ko:K09809,ko:K21591	-	ko00000,ko01000	glycerophosphotransferase
KIOEMHBE_01652	1.21e-94	tagD	2.7.7.15, 2.7.7.39	-	IM	ko:K00968,ko:K00980	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Glycerol-3-phosphate cytidylyltransferase
KIOEMHBE_01653	2.6e-185	-	-	-	-	-	-	-	-
KIOEMHBE_01654	0.0	pts5ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
KIOEMHBE_01655	0.0	pts4ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KIOEMHBE_01656	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
KIOEMHBE_01657	1.68e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
KIOEMHBE_01658	6.35e-56	-	-	-	-	-	-	-	-
KIOEMHBE_01659	7.55e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
KIOEMHBE_01660	1.27e-181	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
KIOEMHBE_01661	6.72e-203	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
KIOEMHBE_01662	2.52e-209	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
KIOEMHBE_01663	7.87e-266	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
KIOEMHBE_01664	2.13e-124	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
KIOEMHBE_01665	1.82e-126	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
KIOEMHBE_01666	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
KIOEMHBE_01667	2.41e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
KIOEMHBE_01668	1.73e-89	-	-	-	-	-	-	-	-
KIOEMHBE_01669	2.37e-123	-	-	-	-	-	-	-	-
KIOEMHBE_01670	5.92e-67	-	-	-	-	-	-	-	-
KIOEMHBE_01671	4.81e-76	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
KIOEMHBE_01672	1.21e-111	-	-	-	-	-	-	-	-
KIOEMHBE_01673	1.76e-280	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
KIOEMHBE_01674	5.33e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KIOEMHBE_01675	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
KIOEMHBE_01676	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
KIOEMHBE_01677	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
KIOEMHBE_01678	7.02e-126	-	-	-	K	-	-	-	Helix-turn-helix domain
KIOEMHBE_01679	3.91e-283	-	-	-	C	-	-	-	FAD dependent oxidoreductase
KIOEMHBE_01680	1.82e-220	-	-	-	P	-	-	-	Major Facilitator Superfamily
KIOEMHBE_01681	3.16e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KIOEMHBE_01682	2.32e-43	ygzD	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
KIOEMHBE_01683	1.2e-91	-	-	-	-	-	-	-	-
KIOEMHBE_01684	1.05e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KIOEMHBE_01685	5.3e-202	dkgB	-	-	S	-	-	-	reductase
KIOEMHBE_01686	6.07e-117	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
KIOEMHBE_01687	2.02e-131	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC transporter permease
KIOEMHBE_01688	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
KIOEMHBE_01689	1.5e-150	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
KIOEMHBE_01690	9.01e-215	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
KIOEMHBE_01691	7.76e-181	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
KIOEMHBE_01692	2.38e-99	-	-	-	-	-	-	-	-
KIOEMHBE_01693	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
KIOEMHBE_01694	2.4e-180	-	-	-	-	-	-	-	-
KIOEMHBE_01695	4.07e-05	-	-	-	-	-	-	-	-
KIOEMHBE_01696	5.66e-184	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
KIOEMHBE_01697	1.67e-54	-	-	-	-	-	-	-	-
KIOEMHBE_01698	4.29e-166	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KIOEMHBE_01699	9.79e-192	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
KIOEMHBE_01700	1.84e-235	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
KIOEMHBE_01701	1.15e-155	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
KIOEMHBE_01702	7.9e-306	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
KIOEMHBE_01703	1.78e-160	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
KIOEMHBE_01704	3.58e-174	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
KIOEMHBE_01705	1.19e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
KIOEMHBE_01706	2.6e-193	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
KIOEMHBE_01707	7.11e-227	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
KIOEMHBE_01708	1.87e-175	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KIOEMHBE_01709	7.44e-192	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
KIOEMHBE_01710	1.61e-144	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KIOEMHBE_01711	1.45e-261	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
KIOEMHBE_01712	2.39e-174	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
KIOEMHBE_01713	0.0	-	-	-	L	-	-	-	HIRAN domain
KIOEMHBE_01714	1.24e-109	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
KIOEMHBE_01715	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
KIOEMHBE_01716	5.18e-159	-	-	-	-	-	-	-	-
KIOEMHBE_01717	2.07e-191	-	-	-	I	-	-	-	Alpha/beta hydrolase family
KIOEMHBE_01718	0.0	pacL1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
KIOEMHBE_01719	1.34e-183	-	-	-	F	-	-	-	Phosphorylase superfamily
KIOEMHBE_01720	2.92e-38	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
KIOEMHBE_01721	1.72e-142	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
KIOEMHBE_01722	1.27e-98	-	-	-	K	-	-	-	Transcriptional regulator
KIOEMHBE_01723	3.99e-96	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
KIOEMHBE_01724	5.51e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
KIOEMHBE_01725	5.38e-290	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
KIOEMHBE_01726	3.98e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
KIOEMHBE_01727	2.79e-274	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
KIOEMHBE_01729	2.16e-204	morA	-	-	S	-	-	-	reductase
KIOEMHBE_01730	8.21e-213	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo keto reductase
KIOEMHBE_01731	1.92e-106	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase like
KIOEMHBE_01732	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
KIOEMHBE_01733	7.45e-103	-	-	-	-	-	-	-	-
KIOEMHBE_01734	0.0	-	-	-	-	-	-	-	-
KIOEMHBE_01735	6.49e-268	-	-	-	C	-	-	-	Oxidoreductase
KIOEMHBE_01736	3.28e-193	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
KIOEMHBE_01737	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KIOEMHBE_01738	2.57e-128	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
KIOEMHBE_01740	4.37e-167	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
KIOEMHBE_01741	4.14e-72	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
KIOEMHBE_01742	2.09e-171	-	-	-	-	-	-	-	-
KIOEMHBE_01743	1.57e-191	-	-	-	-	-	-	-	-
KIOEMHBE_01744	3.37e-115	-	-	-	-	-	-	-	-
KIOEMHBE_01745	1.01e-184	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
KIOEMHBE_01746	6.03e-218	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
KIOEMHBE_01747	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
KIOEMHBE_01748	8.03e-151	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
KIOEMHBE_01749	0.0	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
KIOEMHBE_01750	9.67e-98	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
KIOEMHBE_01752	5.29e-121	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KIOEMHBE_01753	2.35e-243	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
KIOEMHBE_01754	3.05e-236	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
KIOEMHBE_01755	7.88e-131	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
KIOEMHBE_01756	6.76e-75	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
KIOEMHBE_01757	2.32e-171	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
KIOEMHBE_01758	2.65e-245	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
KIOEMHBE_01759	1.83e-231	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
KIOEMHBE_01760	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
KIOEMHBE_01761	4.15e-191	yxeH	-	-	S	-	-	-	hydrolase
KIOEMHBE_01762	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
KIOEMHBE_01763	1.14e-202	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
KIOEMHBE_01764	2.87e-101	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
KIOEMHBE_01765	2.96e-89	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KIOEMHBE_01766	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KIOEMHBE_01767	5.84e-312	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KIOEMHBE_01768	2.28e-290	sdaC	-	-	E	ko:K03837	-	ko00000,ko02000	amino acid
KIOEMHBE_01769	7.51e-159	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
KIOEMHBE_01770	2.81e-202	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
KIOEMHBE_01771	6.59e-170	-	-	-	S	-	-	-	YheO-like PAS domain
KIOEMHBE_01772	4.01e-36	-	-	-	-	-	-	-	-
KIOEMHBE_01773	2.08e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KIOEMHBE_01774	1.26e-305	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KIOEMHBE_01775	1.91e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
KIOEMHBE_01776	2.57e-274	-	-	-	J	-	-	-	translation release factor activity
KIOEMHBE_01777	3.14e-164	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
KIOEMHBE_01778	5.35e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
KIOEMHBE_01779	1.6e-194	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
KIOEMHBE_01780	1.84e-189	-	-	-	-	-	-	-	-
KIOEMHBE_01781	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KIOEMHBE_01782	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KIOEMHBE_01783	9.32e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KIOEMHBE_01784	4.79e-273	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KIOEMHBE_01785	2.58e-85	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
KIOEMHBE_01786	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
KIOEMHBE_01787	1.37e-248	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	ABC transporter, substratebinding protein
KIOEMHBE_01788	3.03e-202	-	-	-	U	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KIOEMHBE_01789	5.79e-171	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
KIOEMHBE_01790	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
KIOEMHBE_01791	7.48e-260	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
KIOEMHBE_01792	8.87e-245	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KIOEMHBE_01793	2.29e-292	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KIOEMHBE_01794	2.36e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
KIOEMHBE_01795	3.52e-273	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
KIOEMHBE_01796	1.52e-240	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KIOEMHBE_01797	1.3e-110	queT	-	-	S	-	-	-	QueT transporter
KIOEMHBE_01798	1.4e-147	-	-	-	S	-	-	-	(CBS) domain
KIOEMHBE_01799	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
KIOEMHBE_01800	2.79e-226	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
KIOEMHBE_01801	1.43e-129	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KIOEMHBE_01802	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KIOEMHBE_01803	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
KIOEMHBE_01804	7.72e-57	yabO	-	-	J	-	-	-	S4 domain protein
KIOEMHBE_01806	2.02e-83	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
KIOEMHBE_01807	1.07e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
KIOEMHBE_01808	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KIOEMHBE_01809	4.3e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
KIOEMHBE_01810	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KIOEMHBE_01811	1.93e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KIOEMHBE_01812	5.33e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KIOEMHBE_01813	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
KIOEMHBE_01814	1.97e-110	-	-	-	S	-	-	-	Pfam:DUF3816
KIOEMHBE_01815	1.21e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KIOEMHBE_01816	1.27e-143	-	-	-	-	-	-	-	-
KIOEMHBE_01817	1.08e-229	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
KIOEMHBE_01818	3.84e-185	-	-	-	S	-	-	-	Peptidase_C39 like family
KIOEMHBE_01819	1.04e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
KIOEMHBE_01820	3.38e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
KIOEMHBE_01821	9.38e-189	-	-	-	KT	-	-	-	helix_turn_helix, mercury resistance
KIOEMHBE_01822	3.41e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KIOEMHBE_01823	1.86e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
KIOEMHBE_01824	1.2e-240	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
KIOEMHBE_01825	1.18e-155	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KIOEMHBE_01826	2.76e-117	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
KIOEMHBE_01827	5.72e-238	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
KIOEMHBE_01828	3.55e-127	ywjB	-	-	H	-	-	-	RibD C-terminal domain
KIOEMHBE_01829	9.35e-257	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KIOEMHBE_01830	7.1e-152	-	-	-	S	-	-	-	Membrane
KIOEMHBE_01831	2.11e-199	mleP3	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
KIOEMHBE_01832	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
KIOEMHBE_01833	4.32e-261	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
KIOEMHBE_01834	7.22e-163	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
KIOEMHBE_01835	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
KIOEMHBE_01836	4.03e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
KIOEMHBE_01837	8.99e-133	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
KIOEMHBE_01838	2.17e-222	-	-	-	S	-	-	-	Conserved hypothetical protein 698
KIOEMHBE_01839	5.9e-194	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
KIOEMHBE_01840	0.0	tagE5	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
KIOEMHBE_01841	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
KIOEMHBE_01843	2.24e-78	-	-	-	M	-	-	-	LysM domain
KIOEMHBE_01844	6.5e-119	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
KIOEMHBE_01845	1.65e-212	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KIOEMHBE_01846	3.91e-269	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
KIOEMHBE_01847	6.27e-166	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
KIOEMHBE_01848	4.72e-72	cmd	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
KIOEMHBE_01849	4.77e-100	yphH	-	-	S	-	-	-	Cupin domain
KIOEMHBE_01850	5.19e-103	-	-	-	K	-	-	-	transcriptional regulator, MerR family
KIOEMHBE_01851	4.87e-298	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
KIOEMHBE_01852	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
KIOEMHBE_01853	1.74e-156	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KIOEMHBE_01855	1.19e-150	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KIOEMHBE_01856	3.18e-141	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
KIOEMHBE_01857	1.03e-150	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
KIOEMHBE_01859	4.86e-111	-	-	-	-	-	-	-	-
KIOEMHBE_01860	1.04e-110	yvbK	-	-	K	-	-	-	GNAT family
KIOEMHBE_01861	9.76e-50	-	-	-	-	-	-	-	-
KIOEMHBE_01862	2.81e-64	-	-	-	-	-	-	-	-
KIOEMHBE_01863	7.44e-143	pgm8	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
KIOEMHBE_01864	6.09e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
KIOEMHBE_01865	1.51e-200	-	-	-	K	-	-	-	LysR substrate binding domain
KIOEMHBE_01866	1.52e-135	-	-	-	GM	-	-	-	NAD(P)H-binding
KIOEMHBE_01867	1.66e-247	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
KIOEMHBE_01868	2.9e-194	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
KIOEMHBE_01869	1.28e-45	-	-	-	-	-	-	-	-
KIOEMHBE_01870	2.1e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
KIOEMHBE_01871	2.09e-124	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
KIOEMHBE_01872	1.76e-162	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
KIOEMHBE_01873	1.03e-40	-	-	-	-	-	-	-	-
KIOEMHBE_01874	0.0	-	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
KIOEMHBE_01875	0.0	cadA	-	-	P	-	-	-	P-type ATPase
KIOEMHBE_01877	9.45e-160	-	-	-	S	-	-	-	YjbR
KIOEMHBE_01878	4.04e-37	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
KIOEMHBE_01879	3.23e-215	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
KIOEMHBE_01880	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KIOEMHBE_01881	1.44e-255	glmS2	-	-	M	-	-	-	SIS domain
KIOEMHBE_01882	2.07e-35	-	-	-	S	-	-	-	Belongs to the LOG family
KIOEMHBE_01883	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
KIOEMHBE_01884	3.98e-315	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
KIOEMHBE_01885	5.85e-92	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KIOEMHBE_01886	5.38e-92	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KIOEMHBE_01887	4.75e-112	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
KIOEMHBE_01888	1.07e-206	-	-	-	GM	-	-	-	NmrA-like family
KIOEMHBE_01889	2.14e-86	-	-	-	K	ko:K22296	-	ko00000,ko03000	Winged helix DNA-binding domain
KIOEMHBE_01890	9.97e-94	spxA	-	-	P	ko:K16509	-	ko00000	ArsC family
KIOEMHBE_01891	3.46e-87	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
KIOEMHBE_01892	1.7e-70	-	-	-	-	-	-	-	-
KIOEMHBE_01893	4.98e-275	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
KIOEMHBE_01894	2.11e-82	-	-	-	-	-	-	-	-
KIOEMHBE_01895	1.36e-112	-	-	-	-	-	-	-	-
KIOEMHBE_01896	4.58e-103	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
KIOEMHBE_01897	3.78e-73	-	-	-	-	-	-	-	-
KIOEMHBE_01898	4.79e-21	-	-	-	-	-	-	-	-
KIOEMHBE_01899	3.57e-150	-	-	-	GM	-	-	-	NmrA-like family
KIOEMHBE_01900	2.52e-107	-	-	-	S	ko:K02348	-	ko00000	GNAT family
KIOEMHBE_01901	9.43e-203	-	-	-	EG	-	-	-	EamA-like transporter family
KIOEMHBE_01902	2.66e-155	-	-	-	S	-	-	-	membrane
KIOEMHBE_01903	1.47e-144	-	-	-	S	-	-	-	VIT family
KIOEMHBE_01904	4.38e-243	pva2	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
KIOEMHBE_01905	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
KIOEMHBE_01906	8.01e-97	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
KIOEMHBE_01907	4.26e-54	-	-	-	-	-	-	-	-
KIOEMHBE_01908	3.43e-96	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
KIOEMHBE_01909	8.8e-315	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
KIOEMHBE_01910	7.21e-35	-	-	-	-	-	-	-	-
KIOEMHBE_01911	2.55e-65	-	-	-	-	-	-	-	-
KIOEMHBE_01912	2.51e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF1398)
KIOEMHBE_01913	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
KIOEMHBE_01914	1.77e-282	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
KIOEMHBE_01915	9.92e-230	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
KIOEMHBE_01916	6.1e-101	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
KIOEMHBE_01917	1.14e-110	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
KIOEMHBE_01918	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
KIOEMHBE_01919	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
KIOEMHBE_01920	2.3e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
KIOEMHBE_01921	1.36e-209	yvgN	-	-	C	-	-	-	Aldo keto reductase
KIOEMHBE_01922	2.57e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
KIOEMHBE_01923	1.7e-101	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
KIOEMHBE_01924	1.5e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
KIOEMHBE_01925	2.69e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KIOEMHBE_01926	5.94e-118	ymdB	-	-	S	-	-	-	Macro domain protein
KIOEMHBE_01927	6.47e-124	-	-	-	K	ko:K22041	-	ko00000,ko03000	transcriptional regulator
KIOEMHBE_01928	1.58e-66	-	-	-	-	-	-	-	-
KIOEMHBE_01929	2.41e-212	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
KIOEMHBE_01930	0.0	-	-	-	-	-	-	-	-
KIOEMHBE_01931	2.08e-161	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
KIOEMHBE_01932	5.03e-43	-	-	-	-	-	-	-	-
KIOEMHBE_01933	2.21e-178	-	-	-	Q	-	-	-	Methyltransferase
KIOEMHBE_01934	2.84e-75	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
KIOEMHBE_01935	1.66e-269	-	-	-	EGP	-	-	-	Major facilitator Superfamily
KIOEMHBE_01936	3.58e-129	-	-	-	K	-	-	-	Helix-turn-helix domain
KIOEMHBE_01937	1.52e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KIOEMHBE_01938	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
KIOEMHBE_01939	1.84e-67	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
KIOEMHBE_01940	7.09e-180	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
KIOEMHBE_01941	8.34e-228	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KIOEMHBE_01942	6.62e-62	-	-	-	-	-	-	-	-
KIOEMHBE_01943	1.55e-311	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KIOEMHBE_01944	3.02e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
KIOEMHBE_01945	4.24e-218	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KIOEMHBE_01946	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
KIOEMHBE_01947	0.0	-	3.1.4.53	-	S	ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
KIOEMHBE_01948	0.0	cps4J	-	-	S	-	-	-	MatE
KIOEMHBE_01949	4.82e-228	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
KIOEMHBE_01950	1.91e-297	-	-	-	-	-	-	-	-
KIOEMHBE_01951	7.88e-48	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
KIOEMHBE_01952	1.82e-132	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
KIOEMHBE_01953	1.43e-223	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
KIOEMHBE_01954	3.18e-162	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
KIOEMHBE_01955	8.71e-231	cps4D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
KIOEMHBE_01956	5.54e-189	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
KIOEMHBE_01957	2.02e-156	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
KIOEMHBE_01958	8.45e-162	epsB	-	-	M	-	-	-	biosynthesis protein
KIOEMHBE_01959	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KIOEMHBE_01960	3.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KIOEMHBE_01961	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
KIOEMHBE_01962	5.12e-31	-	-	-	-	-	-	-	-
KIOEMHBE_01963	6.47e-95	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
KIOEMHBE_01964	1.3e-65	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
KIOEMHBE_01965	9.6e-143	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
KIOEMHBE_01966	7.8e-300	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KIOEMHBE_01967	3.21e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KIOEMHBE_01968	4.38e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KIOEMHBE_01969	9.34e-201	-	-	-	S	-	-	-	Tetratricopeptide repeat
KIOEMHBE_01970	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KIOEMHBE_01971	1.29e-200	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KIOEMHBE_01972	1.8e-135	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
KIOEMHBE_01973	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KIOEMHBE_01974	1.18e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
KIOEMHBE_01975	8.43e-240	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
KIOEMHBE_01976	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
KIOEMHBE_01977	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
KIOEMHBE_01978	2.1e-161	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
KIOEMHBE_01979	1.05e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
KIOEMHBE_01980	7.04e-108	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KIOEMHBE_01981	8.61e-132	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
KIOEMHBE_01982	1.91e-66	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
KIOEMHBE_01983	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KIOEMHBE_01984	1.45e-260	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
KIOEMHBE_01985	0.0	-	-	-	-	-	-	-	-
KIOEMHBE_01986	1.56e-262	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
KIOEMHBE_01987	3.5e-205	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KIOEMHBE_01988	2.97e-244	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
KIOEMHBE_01989	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
KIOEMHBE_01990	1.55e-230	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
KIOEMHBE_01991	5.55e-100	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
KIOEMHBE_01992	6.61e-29	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
KIOEMHBE_01993	1.11e-33	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
KIOEMHBE_01994	3.38e-50	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
KIOEMHBE_01995	1.29e-235	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
KIOEMHBE_01996	5.91e-297	-	-	-	P	ko:K06610	-	ko00000,ko02000	Major Facilitator Superfamily
KIOEMHBE_01997	0.0	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
KIOEMHBE_01998	2.9e-293	-	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
KIOEMHBE_01999	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
KIOEMHBE_02000	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
KIOEMHBE_02001	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
KIOEMHBE_02002	1.95e-140	aqpZ	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
KIOEMHBE_02003	3.7e-279	-	-	-	S	-	-	-	associated with various cellular activities
KIOEMHBE_02004	9.34e-317	-	-	-	S	-	-	-	Putative metallopeptidase domain
KIOEMHBE_02005	1.03e-65	-	-	-	-	-	-	-	-
KIOEMHBE_02006	8.19e-134	yezE	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
KIOEMHBE_02007	7.83e-60	-	-	-	-	-	-	-	-
KIOEMHBE_02008	4.23e-129	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
KIOEMHBE_02009	8.67e-160	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
KIOEMHBE_02010	1.83e-235	-	-	-	S	-	-	-	Cell surface protein
KIOEMHBE_02011	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
KIOEMHBE_02012	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
KIOEMHBE_02013	1.06e-106	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KIOEMHBE_02014	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
KIOEMHBE_02015	1.82e-152	rcfA	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
KIOEMHBE_02016	2.98e-44	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
KIOEMHBE_02017	4.27e-126	dpsB	-	-	P	-	-	-	Belongs to the Dps family
KIOEMHBE_02018	1.01e-26	-	-	-	-	-	-	-	-
KIOEMHBE_02019	4.82e-55	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
KIOEMHBE_02020	5.73e-73	trxA3	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
KIOEMHBE_02021	9.44e-183	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
KIOEMHBE_02022	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
KIOEMHBE_02023	8.06e-232	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
KIOEMHBE_02024	1.5e-165	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
KIOEMHBE_02025	4.16e-175	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KIOEMHBE_02026	4.84e-230	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
KIOEMHBE_02027	1.12e-134	-	-	-	K	-	-	-	transcriptional regulator
KIOEMHBE_02029	9.39e-84	-	-	-	-	-	-	-	-
KIOEMHBE_02031	5.77e-81	-	-	-	-	-	-	-	-
KIOEMHBE_02032	6.18e-71	-	-	-	-	-	-	-	-
KIOEMHBE_02033	1.88e-96	-	-	-	M	-	-	-	PFAM NLP P60 protein
KIOEMHBE_02034	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
KIOEMHBE_02035	4.45e-38	-	-	-	-	-	-	-	-
KIOEMHBE_02036	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
KIOEMHBE_02037	3.81e-150	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KIOEMHBE_02038	3.08e-113	-	-	-	K	-	-	-	Winged helix DNA-binding domain
KIOEMHBE_02039	1.63e-176	yesN	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
KIOEMHBE_02040	3.17e-170	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
KIOEMHBE_02041	1.56e-71	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
KIOEMHBE_02042	2.56e-131	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
KIOEMHBE_02043	8.07e-163	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
KIOEMHBE_02044	6.36e-134	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KIOEMHBE_02045	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
KIOEMHBE_02046	1.56e-108	-	-	-	-	-	-	-	-
KIOEMHBE_02047	5.97e-96	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
KIOEMHBE_02048	9.2e-243	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KIOEMHBE_02049	7.3e-245	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KIOEMHBE_02050	3.7e-30	-	-	-	-	-	-	-	-
KIOEMHBE_02051	1.38e-131	-	-	-	-	-	-	-	-
KIOEMHBE_02052	3.46e-210	-	-	-	K	-	-	-	LysR substrate binding domain
KIOEMHBE_02053	4.34e-314	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
KIOEMHBE_02054	0.0	-	4.1.1.98	-	H	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
KIOEMHBE_02055	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
KIOEMHBE_02056	1.37e-182	-	-	-	S	-	-	-	zinc-ribbon domain
KIOEMHBE_02058	4.29e-50	-	-	-	-	-	-	-	-
KIOEMHBE_02059	1.4e-137	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
KIOEMHBE_02060	1.4e-20	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
KIOEMHBE_02061	2.35e-231	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
KIOEMHBE_02062	0.0	-	-	-	I	-	-	-	acetylesterase activity
KIOEMHBE_02063	6.08e-78	-	-	-	M	-	-	-	Collagen binding domain
KIOEMHBE_02064	6.92e-206	yicL	-	-	EG	-	-	-	EamA-like transporter family
KIOEMHBE_02065	6.12e-166	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
KIOEMHBE_02066	3.39e-225	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
KIOEMHBE_02067	5.93e-144	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
KIOEMHBE_02068	5.07e-62	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
KIOEMHBE_02069	3.06e-206	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
KIOEMHBE_02070	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
KIOEMHBE_02071	9.86e-117	-	-	-	-	-	-	-	-
KIOEMHBE_02072	1.02e-164	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
KIOEMHBE_02073	9.21e-234	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
KIOEMHBE_02074	7.39e-121	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
KIOEMHBE_02075	5.85e-204	ccpB	-	-	K	-	-	-	lacI family
KIOEMHBE_02076	2.21e-154	yceE	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
KIOEMHBE_02077	8.08e-154	ydgI3	-	-	C	-	-	-	Nitroreductase family
KIOEMHBE_02078	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
KIOEMHBE_02079	4.21e-150	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
KIOEMHBE_02080	5.82e-198	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
KIOEMHBE_02081	6.97e-216	XK27_00670	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
KIOEMHBE_02082	0.0	-	-	-	-	-	-	-	-
KIOEMHBE_02083	4.71e-81	-	-	-	-	-	-	-	-
KIOEMHBE_02084	5.52e-242	-	-	-	S	-	-	-	Cell surface protein
KIOEMHBE_02085	1.27e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
KIOEMHBE_02086	5.06e-82	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
KIOEMHBE_02087	3.13e-42	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
KIOEMHBE_02088	2.78e-158	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
KIOEMHBE_02089	5.21e-180	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
KIOEMHBE_02090	2.29e-193	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
KIOEMHBE_02091	4.54e-191	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
KIOEMHBE_02092	1.04e-269	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
KIOEMHBE_02094	1.15e-43	-	-	-	-	-	-	-	-
KIOEMHBE_02095	4.1e-223	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
KIOEMHBE_02096	3.22e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
KIOEMHBE_02097	7.24e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
KIOEMHBE_02098	1.74e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KIOEMHBE_02099	7.01e-76	ftsL	-	-	D	-	-	-	Cell division protein FtsL
KIOEMHBE_02100	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
KIOEMHBE_02101	2.81e-231	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KIOEMHBE_02102	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KIOEMHBE_02103	2.04e-252	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KIOEMHBE_02104	2.34e-208	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KIOEMHBE_02105	3.55e-312	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KIOEMHBE_02106	9.39e-295	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KIOEMHBE_02107	1.56e-93	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KIOEMHBE_02108	6.45e-49	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
KIOEMHBE_02109	2.06e-187	ylmH	-	-	S	-	-	-	S4 domain protein
KIOEMHBE_02110	6.52e-124	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
KIOEMHBE_02111	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KIOEMHBE_02112	3.46e-242	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KIOEMHBE_02113	3.51e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
KIOEMHBE_02114	7.74e-47	-	-	-	-	-	-	-	-
KIOEMHBE_02115	5.85e-158	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KIOEMHBE_02116	8.09e-275	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
KIOEMHBE_02117	4.94e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
KIOEMHBE_02118	1.53e-284	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KIOEMHBE_02119	9.64e-307	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
KIOEMHBE_02120	4.64e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
KIOEMHBE_02121	4.17e-153	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
KIOEMHBE_02122	2.02e-247	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
KIOEMHBE_02123	0.0	-	-	-	N	-	-	-	domain, Protein
KIOEMHBE_02124	2.41e-157	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
KIOEMHBE_02125	1.02e-155	-	-	-	S	-	-	-	repeat protein
KIOEMHBE_02126	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KIOEMHBE_02127	5.35e-220	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KIOEMHBE_02128	2.62e-168	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
KIOEMHBE_02129	2.16e-39	-	-	-	-	-	-	-	-
KIOEMHBE_02130	3.45e-240	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
KIOEMHBE_02131	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KIOEMHBE_02132	4.86e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
KIOEMHBE_02133	6.45e-111	-	-	-	-	-	-	-	-
KIOEMHBE_02134	3.95e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KIOEMHBE_02135	1.21e-268	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
KIOEMHBE_02136	8.65e-228	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
KIOEMHBE_02137	2.36e-285	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KIOEMHBE_02138	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
KIOEMHBE_02139	2.15e-209	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
KIOEMHBE_02140	2.64e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
KIOEMHBE_02141	7.1e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
KIOEMHBE_02142	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
KIOEMHBE_02143	4.84e-227	-	-	-	-	-	-	-	-
KIOEMHBE_02144	4.54e-54	-	-	-	-	-	-	-	-
KIOEMHBE_02146	8.83e-317	-	-	-	EGP	-	-	-	Major Facilitator
KIOEMHBE_02147	5.61e-216	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
KIOEMHBE_02148	4.26e-109	cvpA	-	-	S	-	-	-	Colicin V production protein
KIOEMHBE_02149	9.61e-84	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KIOEMHBE_02150	1.59e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
KIOEMHBE_02151	1.8e-134	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
KIOEMHBE_02152	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
KIOEMHBE_02153	2.01e-134	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
KIOEMHBE_02154	5.59e-271	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
KIOEMHBE_02155	3.91e-124	tag2	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
KIOEMHBE_02156	8.03e-28	-	-	-	-	-	-	-	-
KIOEMHBE_02157	1.3e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
KIOEMHBE_02158	7.27e-73	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
KIOEMHBE_02159	2.94e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
KIOEMHBE_02160	1.97e-60	qacH	-	-	U	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
KIOEMHBE_02161	1.63e-77	-	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
KIOEMHBE_02162	1.38e-275	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
KIOEMHBE_02163	3.1e-228	ydbI	-	-	K	-	-	-	AI-2E family transporter
KIOEMHBE_02164	1.07e-211	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KIOEMHBE_02165	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
KIOEMHBE_02167	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
KIOEMHBE_02168	4.62e-107	-	-	-	-	-	-	-	-
KIOEMHBE_02170	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KIOEMHBE_02171	1.02e-187	ptp2	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
KIOEMHBE_02172	4.17e-235	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KIOEMHBE_02173	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KIOEMHBE_02174	3.66e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KIOEMHBE_02175	2.05e-72	-	-	-	S	-	-	-	Enterocin A Immunity
KIOEMHBE_02176	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
KIOEMHBE_02177	1.49e-253	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
KIOEMHBE_02178	9.07e-233	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
KIOEMHBE_02179	2.85e-210	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
KIOEMHBE_02180	0.0	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
KIOEMHBE_02181	7.02e-151	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
KIOEMHBE_02182	1.03e-34	-	-	-	-	-	-	-	-
KIOEMHBE_02183	1.56e-185	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
KIOEMHBE_02184	2.88e-164	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
KIOEMHBE_02185	4.14e-84	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
KIOEMHBE_02186	2.8e-135	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
KIOEMHBE_02187	1.33e-100	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
KIOEMHBE_02188	7.47e-77	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
KIOEMHBE_02189	6.46e-49	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
KIOEMHBE_02190	1.28e-77	-	-	-	S	-	-	-	Enterocin A Immunity
KIOEMHBE_02191	1.55e-114	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
KIOEMHBE_02192	1.16e-135	-	-	-	-	-	-	-	-
KIOEMHBE_02193	8.44e-304	-	-	-	S	-	-	-	module of peptide synthetase
KIOEMHBE_02194	2.95e-100	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
KIOEMHBE_02196	1.25e-164	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
KIOEMHBE_02197	0.0	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KIOEMHBE_02198	7.54e-200	-	-	-	GM	-	-	-	NmrA-like family
KIOEMHBE_02199	4.08e-101	-	-	-	K	-	-	-	MerR family regulatory protein
KIOEMHBE_02200	2.81e-167	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
KIOEMHBE_02201	2.88e-106	gtcA3	-	-	S	-	-	-	GtrA-like protein
KIOEMHBE_02202	3.35e-157	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KIOEMHBE_02203	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
KIOEMHBE_02204	1.18e-94	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
KIOEMHBE_02205	7.03e-62	-	-	-	-	-	-	-	-
KIOEMHBE_02206	1.81e-150	-	-	-	S	-	-	-	SNARE associated Golgi protein
KIOEMHBE_02207	8.58e-65	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
KIOEMHBE_02208	7.89e-124	-	-	-	P	-	-	-	Cadmium resistance transporter
KIOEMHBE_02209	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KIOEMHBE_02210	3.93e-38	-	-	-	P	-	-	-	Concanavalin A-like lectin/glucanases superfamily
KIOEMHBE_02212	2.03e-84	-	-	-	-	-	-	-	-
KIOEMHBE_02213	1.58e-204	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
KIOEMHBE_02214	1.21e-73	-	-	-	-	-	-	-	-
KIOEMHBE_02215	1.24e-194	-	-	-	K	-	-	-	Helix-turn-helix domain
KIOEMHBE_02216	3.91e-100	pts23A	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KIOEMHBE_02217	7.47e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
KIOEMHBE_02218	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KIOEMHBE_02219	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KIOEMHBE_02220	4.32e-235	-	-	-	GM	-	-	-	Male sterility protein
KIOEMHBE_02221	2.1e-99	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
KIOEMHBE_02222	4.61e-101	-	-	-	M	-	-	-	LysM domain
KIOEMHBE_02223	7.94e-126	-	-	-	M	-	-	-	Lysin motif
KIOEMHBE_02224	5.71e-138	-	-	-	S	-	-	-	SdpI/YhfL protein family
KIOEMHBE_02225	1.58e-72	nudA	-	-	S	-	-	-	ASCH
KIOEMHBE_02226	5.76e-212	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
KIOEMHBE_02227	3.57e-120	-	-	-	-	-	-	-	-
KIOEMHBE_02228	1.92e-155	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
KIOEMHBE_02229	3.55e-281	-	-	-	T	-	-	-	diguanylate cyclase
KIOEMHBE_02230	7.43e-97	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
KIOEMHBE_02231	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
KIOEMHBE_02232	2.31e-277	-	-	-	-	-	-	-	-
KIOEMHBE_02233	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KIOEMHBE_02234	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
KIOEMHBE_02236	3.23e-290	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
KIOEMHBE_02237	2.96e-209	yhxD	-	-	IQ	-	-	-	KR domain
KIOEMHBE_02239	1.97e-92	-	-	-	-	-	-	-	-
KIOEMHBE_02240	1.43e-184	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KIOEMHBE_02241	0.0	-	-	-	E	-	-	-	Amino Acid
KIOEMHBE_02242	4.8e-86	lysM	-	-	M	-	-	-	LysM domain
KIOEMHBE_02243	4.2e-286	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
KIOEMHBE_02244	6.8e-272	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
KIOEMHBE_02245	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
KIOEMHBE_02246	1.23e-57	-	-	-	S	-	-	-	Cupredoxin-like domain
KIOEMHBE_02247	1.36e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
KIOEMHBE_02248	2.69e-316	dinF	-	-	V	-	-	-	MatE
KIOEMHBE_02249	1.79e-42	-	-	-	-	-	-	-	-
KIOEMHBE_02251	8.2e-102	yybD	-	-	S	ko:K02348	-	ko00000	Acetyltransferase (GNAT) domain
KIOEMHBE_02252	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
KIOEMHBE_02253	4.64e-106	-	-	-	-	-	-	-	-
KIOEMHBE_02254	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
KIOEMHBE_02255	1.04e-136	-	-	-	-	-	-	-	-
KIOEMHBE_02256	0.0	celR	-	-	K	-	-	-	PRD domain
KIOEMHBE_02257	1.34e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
KIOEMHBE_02258	2.37e-68	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
KIOEMHBE_02259	4.9e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
KIOEMHBE_02260	1.71e-277	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KIOEMHBE_02261	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KIOEMHBE_02262	3.5e-271	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
KIOEMHBE_02263	2.34e-146	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
KIOEMHBE_02264	1.65e-46	dltC2	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KIOEMHBE_02265	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	Alanine-glyoxylate amino-transferase
KIOEMHBE_02266	8.08e-133	argO	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
KIOEMHBE_02267	5.58e-271	arcT	-	-	E	-	-	-	Aminotransferase
KIOEMHBE_02268	2.07e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
KIOEMHBE_02269	2.43e-18	-	-	-	-	-	-	-	-
KIOEMHBE_02270	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
KIOEMHBE_02271	9.94e-71	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
KIOEMHBE_02272	4.47e-296	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
KIOEMHBE_02273	0.0	yhaN	-	-	L	-	-	-	AAA domain
KIOEMHBE_02274	1.03e-240	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
KIOEMHBE_02275	1.05e-272	-	-	-	-	-	-	-	-
KIOEMHBE_02276	2.41e-233	-	-	-	M	-	-	-	Peptidase family S41
KIOEMHBE_02277	1.09e-225	-	-	-	K	-	-	-	LysR substrate binding domain
KIOEMHBE_02278	9.9e-144	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
KIOEMHBE_02279	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
KIOEMHBE_02280	4.43e-129	-	-	-	-	-	-	-	-
KIOEMHBE_02281	1.17e-100	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
KIOEMHBE_02282	1.15e-235	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
KIOEMHBE_02283	7.78e-20	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KIOEMHBE_02284	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KIOEMHBE_02285	4.29e-26	-	-	-	S	-	-	-	NUDIX domain
KIOEMHBE_02286	0.0	-	-	-	S	-	-	-	membrane
KIOEMHBE_02287	4.26e-218	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KIOEMHBE_02288	2.61e-95	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
KIOEMHBE_02289	2.08e-284	ribA	3.5.4.25, 4.1.99.12	-	H	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
KIOEMHBE_02290	1.23e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KIOEMHBE_02291	5.21e-137	-	-	-	S	ko:K09962	-	ko00000	Nucleotidyltransferase
KIOEMHBE_02292	1.96e-137	-	-	-	-	-	-	-	-
KIOEMHBE_02293	3.3e-151	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
KIOEMHBE_02294	1.08e-95	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KIOEMHBE_02295	2.91e-29	-	-	-	-	-	-	-	-
KIOEMHBE_02296	1.72e-21	-	-	-	-	-	-	-	-
KIOEMHBE_02300	4.43e-168	-	-	-	S	-	-	-	Phage minor structural protein
KIOEMHBE_02301	2.29e-79	-	-	-	S	-	-	-	Phage tail protein
KIOEMHBE_02302	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
KIOEMHBE_02303	6.36e-34	-	-	-	-	-	-	-	-
KIOEMHBE_02304	1.35e-75	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
KIOEMHBE_02305	3.86e-50	-	-	-	S	-	-	-	Phage tail tube protein
KIOEMHBE_02306	7.47e-74	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
KIOEMHBE_02307	2.25e-86	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
KIOEMHBE_02308	3.45e-76	-	-	-	S	-	-	-	Phage head-tail joining protein
KIOEMHBE_02309	9.36e-65	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
KIOEMHBE_02310	1.03e-254	-	-	-	S	-	-	-	Phage capsid family
KIOEMHBE_02311	5.99e-164	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
KIOEMHBE_02312	7.49e-96	-	-	-	S	-	-	-	Phage portal protein
KIOEMHBE_02313	6.68e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF1056)
KIOEMHBE_02314	0.0	-	-	-	S	-	-	-	Phage Terminase
KIOEMHBE_02315	6.68e-103	-	-	-	L	-	-	-	Phage terminase, small subunit
KIOEMHBE_02317	7.81e-113	-	-	-	L	-	-	-	HNH nucleases
KIOEMHBE_02318	1.13e-84	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
KIOEMHBE_02319	2.2e-23	-	-	-	-	-	-	-	-
KIOEMHBE_02320	5.27e-72	-	-	-	-	-	-	-	-
KIOEMHBE_02324	2.95e-06	-	-	-	-	-	-	-	-
KIOEMHBE_02325	4.01e-87	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
KIOEMHBE_02327	2.84e-169	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
KIOEMHBE_02329	3.98e-151	-	-	-	S	-	-	-	AAA domain
KIOEMHBE_02330	4.24e-188	-	-	-	S	-	-	-	Protein of unknown function (DUF1351)
KIOEMHBE_02337	1.56e-27	-	-	-	-	-	-	-	-
KIOEMHBE_02338	2.59e-99	-	-	-	K	-	-	-	Peptidase S24-like
KIOEMHBE_02345	6.15e-75	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
KIOEMHBE_02346	3.73e-131	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
KIOEMHBE_02347	2.33e-283	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
KIOEMHBE_02348	1.07e-131	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
KIOEMHBE_02349	1.8e-249	-	-	-	C	-	-	-	Aldo/keto reductase family
KIOEMHBE_02351	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KIOEMHBE_02352	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KIOEMHBE_02353	6.27e-316	-	-	-	EGP	-	-	-	Major Facilitator
KIOEMHBE_02358	2.06e-313	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
KIOEMHBE_02359	1.23e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
KIOEMHBE_02360	6.88e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
KIOEMHBE_02361	4.36e-197	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
KIOEMHBE_02362	1.39e-134	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
KIOEMHBE_02363	8.76e-126	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
KIOEMHBE_02364	2.09e-287	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
KIOEMHBE_02365	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
KIOEMHBE_02366	5.69e-191	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
KIOEMHBE_02367	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
KIOEMHBE_02368	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
KIOEMHBE_02369	1.35e-264	-	-	-	EGP	-	-	-	Major facilitator Superfamily
KIOEMHBE_02370	1.54e-219	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KIOEMHBE_02371	1.76e-298	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
KIOEMHBE_02372	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
KIOEMHBE_02373	9.55e-205	-	-	-	I	-	-	-	alpha/beta hydrolase fold
KIOEMHBE_02374	1.01e-167	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
KIOEMHBE_02375	0.0	-	-	-	-	-	-	-	-
KIOEMHBE_02376	2e-52	-	-	-	S	-	-	-	Cytochrome B5
KIOEMHBE_02377	8.68e-118	pts21A	-	-	G	ko:K02755	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KIOEMHBE_02378	6.48e-135	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
KIOEMHBE_02379	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
KIOEMHBE_02380	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
KIOEMHBE_02381	1.08e-221	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
KIOEMHBE_02382	0.0	treP	2.4.1.64	GH65	G	ko:K05342	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
KIOEMHBE_02383	1.3e-203	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
KIOEMHBE_02384	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KIOEMHBE_02385	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KIOEMHBE_02386	1.51e-179	pbg9	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KIOEMHBE_02387	3.72e-200	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
KIOEMHBE_02388	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KIOEMHBE_02389	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KIOEMHBE_02390	2.26e-269	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
KIOEMHBE_02391	6.87e-202	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
KIOEMHBE_02392	1.67e-208	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KIOEMHBE_02393	0.0	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KIOEMHBE_02394	5.44e-174	-	-	-	K	-	-	-	UTRA domain
KIOEMHBE_02395	1.78e-198	estA	-	-	S	-	-	-	Putative esterase
KIOEMHBE_02396	2.97e-83	-	-	-	-	-	-	-	-
KIOEMHBE_02397	5.78e-269	-	-	-	G	-	-	-	Major Facilitator Superfamily
KIOEMHBE_02398	5.79e-209	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
KIOEMHBE_02399	1.66e-215	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KIOEMHBE_02400	1.33e-274	-	-	-	G	-	-	-	Transporter
KIOEMHBE_02401	5.56e-167	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KIOEMHBE_02402	1.23e-228	apbE3	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KIOEMHBE_02403	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
KIOEMHBE_02404	2.86e-85	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
KIOEMHBE_02405	1.42e-245	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
KIOEMHBE_02406	3.69e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
KIOEMHBE_02407	3.51e-252	galM3	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
KIOEMHBE_02408	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
KIOEMHBE_02409	6.39e-169	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
KIOEMHBE_02410	8.05e-166	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
KIOEMHBE_02411	1.9e-230	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
KIOEMHBE_02412	2.26e-209	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KIOEMHBE_02413	6.87e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
KIOEMHBE_02414	1.19e-201	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KIOEMHBE_02415	1.6e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KIOEMHBE_02416	1.63e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
KIOEMHBE_02418	2.53e-106	mutR	-	-	K	ko:K20373,ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
KIOEMHBE_02419	1.81e-273	-	-	-	EGP	ko:K02030	-	ko00000,ko00002,ko02000	Drug resistance transporter Bcr CflA subfamily
KIOEMHBE_02420	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KIOEMHBE_02421	4.64e-92	-	-	-	F	-	-	-	DNA mismatch repair protein MutT
KIOEMHBE_02422	1.12e-205	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
KIOEMHBE_02423	3.56e-170	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
KIOEMHBE_02424	7.71e-228	-	-	-	-	-	-	-	-
KIOEMHBE_02425	1.37e-290	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
KIOEMHBE_02426	1.36e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
KIOEMHBE_02427	4.87e-243	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KIOEMHBE_02428	1.6e-77	chpA	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
KIOEMHBE_02429	5.9e-46	-	-	-	-	-	-	-	-
KIOEMHBE_02430	1.69e-97	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
KIOEMHBE_02431	9.68e-34	-	-	-	-	-	-	-	-
KIOEMHBE_02432	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KIOEMHBE_02433	2.69e-166	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
KIOEMHBE_02434	2.35e-243	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
KIOEMHBE_02435	1.38e-179	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
KIOEMHBE_02436	0.0	-	-	-	L	-	-	-	DNA helicase
KIOEMHBE_02437	4.23e-64	axe	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
KIOEMHBE_02438	3.74e-144	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
KIOEMHBE_02439	4.56e-144	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
KIOEMHBE_02440	8.02e-152	plnU	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
KIOEMHBE_02441	2.6e-140	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
KIOEMHBE_02442	1.17e-306	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
KIOEMHBE_02443	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KIOEMHBE_02444	2.59e-19	-	-	-	-	-	-	-	-
KIOEMHBE_02445	1.93e-31	plnF	-	-	-	-	-	-	-
KIOEMHBE_02446	8.15e-167	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
KIOEMHBE_02447	1.17e-60	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
KIOEMHBE_02448	6.27e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
KIOEMHBE_02449	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
KIOEMHBE_02450	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KIOEMHBE_02451	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
KIOEMHBE_02452	3.97e-229	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
KIOEMHBE_02453	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
KIOEMHBE_02454	4.71e-210	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
KIOEMHBE_02455	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
KIOEMHBE_02456	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
KIOEMHBE_02457	1.63e-163	mleR	-	-	K	-	-	-	LysR substrate binding domain
KIOEMHBE_02458	5.44e-35	mleR	-	-	K	-	-	-	LysR substrate binding domain
KIOEMHBE_02459	0.0	-	-	-	M	-	-	-	domain protein
KIOEMHBE_02461	1.03e-201	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
KIOEMHBE_02462	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
KIOEMHBE_02463	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
KIOEMHBE_02464	2.65e-102	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
KIOEMHBE_02465	1.45e-278	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KIOEMHBE_02466	1.24e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KIOEMHBE_02467	6.7e-148	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
KIOEMHBE_02468	3.38e-227	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
KIOEMHBE_02469	6.33e-46	-	-	-	-	-	-	-	-
KIOEMHBE_02470	1.15e-79	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
KIOEMHBE_02471	4.37e-208	fbpA	-	-	K	-	-	-	Domain of unknown function (DUF814)
KIOEMHBE_02472	1.29e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KIOEMHBE_02473	3.81e-18	-	-	-	-	-	-	-	-
KIOEMHBE_02474	3.18e-77	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KIOEMHBE_02475	5.66e-74	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KIOEMHBE_02476	2.2e-280	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
KIOEMHBE_02477	1.5e-104	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KIOEMHBE_02478	5.55e-22	-	-	-	G	ko:K11203	-	ko00000,ko00002,ko02000	PTS system, fructose subfamily
KIOEMHBE_02479	2.52e-35	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
KIOEMHBE_02480	9.49e-155	fptC	-	-	U	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase system, EIIC
KIOEMHBE_02481	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
KIOEMHBE_02482	2.24e-116	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
KIOEMHBE_02483	3.54e-190	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
KIOEMHBE_02484	2.69e-194	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
KIOEMHBE_02485	6.26e-101	-	-	-	-	-	-	-	-
KIOEMHBE_02486	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KIOEMHBE_02487	2.93e-151	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KIOEMHBE_02488	2.44e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
KIOEMHBE_02489	3.73e-263	-	-	-	S	-	-	-	DUF218 domain
KIOEMHBE_02490	1.06e-232	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
KIOEMHBE_02491	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
KIOEMHBE_02492	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KIOEMHBE_02493	1.6e-200	-	-	-	S	-	-	-	Putative adhesin
KIOEMHBE_02494	1.73e-132	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
KIOEMHBE_02495	2.86e-68	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
KIOEMHBE_02496	1.07e-127	-	-	-	KT	-	-	-	response to antibiotic
KIOEMHBE_02497	1.26e-161	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
KIOEMHBE_02498	3.02e-176	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KIOEMHBE_02499	2.11e-158	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KIOEMHBE_02500	2.13e-167	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
KIOEMHBE_02501	2.07e-302	-	-	-	EK	-	-	-	Aminotransferase, class I
KIOEMHBE_02502	3.36e-216	-	-	-	K	-	-	-	LysR substrate binding domain
KIOEMHBE_02503	3.66e-189	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KIOEMHBE_02504	2.89e-312	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
KIOEMHBE_02505	2.1e-116	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
KIOEMHBE_02506	1.06e-16	-	-	-	-	-	-	-	-
KIOEMHBE_02507	1.96e-21	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
KIOEMHBE_02508	0.0	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
KIOEMHBE_02509	1.32e-101	nrp	-	-	K	ko:K16509	-	ko00000	ArsC family
KIOEMHBE_02510	7.42e-174	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
KIOEMHBE_02511	3.78e-212	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
KIOEMHBE_02512	9.62e-19	-	-	-	-	-	-	-	-
KIOEMHBE_02513	1.51e-85	-	-	-	KOT	ko:K07813	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01002	May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
KIOEMHBE_02514	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
KIOEMHBE_02516	8.76e-72	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
KIOEMHBE_02517	6.67e-165	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
KIOEMHBE_02518	0.0	pox4	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
KIOEMHBE_02519	5.03e-95	-	-	-	K	-	-	-	Transcriptional regulator
KIOEMHBE_02520	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
KIOEMHBE_02521	6.96e-83	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
KIOEMHBE_02522	5.88e-233	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
KIOEMHBE_02523	1.23e-129	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
KIOEMHBE_02524	3.33e-113	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
KIOEMHBE_02525	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
KIOEMHBE_02526	1.56e-185	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
KIOEMHBE_02527	2.53e-209	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
KIOEMHBE_02528	2.03e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KIOEMHBE_02529	4.52e-209	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KIOEMHBE_02530	1.88e-240	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
KIOEMHBE_02531	3.36e-06	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
KIOEMHBE_02532	2.46e-08	-	-	-	-	-	-	-	-
KIOEMHBE_02533	1.23e-26	-	-	-	-	-	-	-	-
KIOEMHBE_02534	1.1e-147	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
KIOEMHBE_02535	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KIOEMHBE_02536	9.2e-317	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KIOEMHBE_02537	2.09e-85	-	-	-	-	-	-	-	-
KIOEMHBE_02538	2.85e-83	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
KIOEMHBE_02539	2.15e-281	-	-	-	S	-	-	-	Membrane
KIOEMHBE_02540	1.04e-59	-	-	-	S	-	-	-	Protein of unknown function (DUF3781)
KIOEMHBE_02541	1.31e-139	yoaZ	-	-	S	-	-	-	intracellular protease amidase
KIOEMHBE_02542	2.33e-56	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
KIOEMHBE_02543	5.36e-76	-	-	-	-	-	-	-	-
KIOEMHBE_02544	1.46e-81	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
KIOEMHBE_02545	5.31e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
KIOEMHBE_02546	3.17e-258	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
KIOEMHBE_02547	2e-62	-	-	-	K	-	-	-	Helix-turn-helix domain
KIOEMHBE_02548	3.87e-115	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
KIOEMHBE_02549	1.06e-72	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
KIOEMHBE_02550	5.53e-114	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KIOEMHBE_02551	6.79e-53	-	-	-	-	-	-	-	-
KIOEMHBE_02552	5.06e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KIOEMHBE_02553	1.6e-233	ydbI	-	-	K	-	-	-	AI-2E family transporter
KIOEMHBE_02554	9.28e-271	xylR	-	-	GK	-	-	-	ROK family
KIOEMHBE_02555	2.92e-143	-	-	-	-	-	-	-	-
KIOEMHBE_02556	3.66e-295	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
KIOEMHBE_02557	3.32e-210	-	-	-	-	-	-	-	-
KIOEMHBE_02558	1.86e-256	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
KIOEMHBE_02559	9.58e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
KIOEMHBE_02560	2.47e-125	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
KIOEMHBE_02561	9.69e-99	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
KIOEMHBE_02562	5.61e-39	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KIOEMHBE_02563	1.74e-184	yxeH	-	-	S	-	-	-	hydrolase
KIOEMHBE_02564	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KIOEMHBE_02565	1.68e-146	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KIOEMHBE_02566	1.17e-305	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
KIOEMHBE_02567	7.29e-61	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system galactitol-specific IIB component
KIOEMHBE_02568	1.58e-101	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KIOEMHBE_02569	0.0	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KIOEMHBE_02570	9.14e-146	gph3	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
KIOEMHBE_02571	5.26e-247	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
KIOEMHBE_02572	8.37e-296	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
KIOEMHBE_02573	6e-60	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
KIOEMHBE_02574	3.99e-106	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KIOEMHBE_02575	1.83e-146	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
KIOEMHBE_02576	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
KIOEMHBE_02577	3.76e-180	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
KIOEMHBE_02578	6.47e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
KIOEMHBE_02579	8.16e-48	-	-	-	I	-	-	-	alpha/beta hydrolase fold
KIOEMHBE_02580	3.21e-127	-	-	-	I	-	-	-	alpha/beta hydrolase fold
KIOEMHBE_02581	3.89e-205	-	-	-	I	-	-	-	alpha/beta hydrolase fold
KIOEMHBE_02582	0.0	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KIOEMHBE_02583	4.01e-263	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KIOEMHBE_02584	9.03e-173	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
KIOEMHBE_02585	1.33e-196	nanK	-	-	GK	-	-	-	ROK family
KIOEMHBE_02586	1.86e-210	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
KIOEMHBE_02587	2.13e-159	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KIOEMHBE_02588	5.6e-292	-	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
KIOEMHBE_02589	1.05e-225	hicD1	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
KIOEMHBE_02590	8.95e-60	-	-	-	-	-	-	-	-
KIOEMHBE_02591	1.99e-26	zmp1	-	-	O	-	-	-	Zinc-dependent metalloprotease
KIOEMHBE_02592	8.36e-154	rpiA2	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
KIOEMHBE_02593	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
KIOEMHBE_02594	5.34e-72	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
KIOEMHBE_02595	1.31e-124	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
KIOEMHBE_02596	1.54e-292	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
KIOEMHBE_02597	5.89e-108	-	-	-	K	-	-	-	Winged helix-turn-helix transcription repressor, HrcA DNA-binding
KIOEMHBE_02598	2.16e-103	-	-	-	-	-	-	-	-
KIOEMHBE_02599	2.32e-101	accB3	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KIOEMHBE_02600	1.49e-223	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
KIOEMHBE_02601	2.42e-207	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
KIOEMHBE_02602	4.06e-102	-	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
KIOEMHBE_02603	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KIOEMHBE_02604	2.7e-230	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
KIOEMHBE_02605	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
KIOEMHBE_02606	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KIOEMHBE_02607	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
KIOEMHBE_02608	2.14e-174	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
KIOEMHBE_02609	0.0	-	-	-	M	-	-	-	domain protein
KIOEMHBE_02610	6.75e-85	-	-	-	M	-	-	-	dTDP-4-dehydrorhamnose reductase activity
KIOEMHBE_02611	1.82e-34	-	-	-	S	-	-	-	Immunity protein 74
KIOEMHBE_02612	1.89e-169	-	-	-	S	-	-	-	KR domain
KIOEMHBE_02613	2.56e-83	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
KIOEMHBE_02614	1.62e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF1905)
KIOEMHBE_02615	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
KIOEMHBE_02616	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
KIOEMHBE_02617	2.09e-213	-	-	-	GM	-	-	-	NmrA-like family
KIOEMHBE_02618	1.15e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KIOEMHBE_02619	5.93e-281	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
KIOEMHBE_02620	6.58e-173	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
KIOEMHBE_02621	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
KIOEMHBE_02622	7.81e-148	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
KIOEMHBE_02623	5.78e-269	-	-	-	EGP	-	-	-	Major Facilitator
KIOEMHBE_02624	3.25e-81	ytcD	-	-	K	-	-	-	Transcriptional regulator, HxlR family
KIOEMHBE_02625	1.06e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
KIOEMHBE_02626	4.13e-157	-	-	-	-	-	-	-	-
KIOEMHBE_02627	7.39e-300	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
KIOEMHBE_02628	1.47e-83	-	-	-	-	-	-	-	-
KIOEMHBE_02629	3.15e-130	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
KIOEMHBE_02630	2.16e-241	ynjC	-	-	S	-	-	-	Cell surface protein
KIOEMHBE_02631	2.63e-146	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
KIOEMHBE_02632	5.83e-87	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
KIOEMHBE_02633	6.57e-226	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
KIOEMHBE_02634	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
KIOEMHBE_02635	4.97e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KIOEMHBE_02636	2.5e-147	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
KIOEMHBE_02637	3.59e-301	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
KIOEMHBE_02639	1.12e-207	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
KIOEMHBE_02640	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KIOEMHBE_02641	9.52e-264	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
KIOEMHBE_02642	2.68e-75	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
KIOEMHBE_02643	1.6e-246	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
KIOEMHBE_02644	7.21e-150	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
KIOEMHBE_02645	6.31e-222	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
KIOEMHBE_02646	1.29e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KIOEMHBE_02647	1.83e-156	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
KIOEMHBE_02648	2.24e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
KIOEMHBE_02649	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
KIOEMHBE_02650	1.52e-231	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
KIOEMHBE_02651	1.64e-17	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
KIOEMHBE_02652	7.12e-170	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KIOEMHBE_02653	9.28e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KIOEMHBE_02654	2.81e-178	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
KIOEMHBE_02655	1.08e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
KIOEMHBE_02671	0.0	acdH	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
KIOEMHBE_02672	8.16e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
KIOEMHBE_02674	2.75e-304	xylP1	-	-	G	-	-	-	MFS/sugar transport protein
KIOEMHBE_02675	5.81e-170	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
KIOEMHBE_02676	3.48e-40	-	-	-	-	-	-	-	-
KIOEMHBE_02677	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
KIOEMHBE_02678	6.4e-54	-	-	-	-	-	-	-	-
KIOEMHBE_02679	7.31e-122	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
KIOEMHBE_02680	6.8e-224	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KIOEMHBE_02681	3.08e-81	-	-	-	S	-	-	-	CHY zinc finger
KIOEMHBE_02682	3.51e-281	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
KIOEMHBE_02683	1.57e-280	-	-	-	-	-	-	-	-
KIOEMHBE_02684	1.15e-198	tagG	-	-	U	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
KIOEMHBE_02685	9.42e-258	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KIOEMHBE_02686	3.93e-59	-	-	-	-	-	-	-	-
KIOEMHBE_02687	4.63e-119	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
KIOEMHBE_02688	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
KIOEMHBE_02689	3.5e-307	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
KIOEMHBE_02690	4.2e-88	gcsH1	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Glycine cleavage H-protein
KIOEMHBE_02691	4.29e-227	-	-	-	-	-	-	-	-
KIOEMHBE_02692	3.27e-168	-	-	-	-	-	-	-	-
KIOEMHBE_02693	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
KIOEMHBE_02694	3.01e-75	-	-	-	-	-	-	-	-
KIOEMHBE_02695	3.74e-284	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KIOEMHBE_02696	9.81e-33	-	-	-	S	ko:K02348	-	ko00000	GNAT family
KIOEMHBE_02697	1.02e-98	-	-	-	K	-	-	-	Transcriptional regulator
KIOEMHBE_02698	9.59e-288	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
KIOEMHBE_02699	2.18e-53	-	-	-	-	-	-	-	-
KIOEMHBE_02700	3.07e-264	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KIOEMHBE_02701	1.31e-179	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KIOEMHBE_02702	6.34e-190	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KIOEMHBE_02703	8.8e-264	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KIOEMHBE_02704	3.68e-125	-	-	-	K	-	-	-	Cupin domain
KIOEMHBE_02705	8.08e-110	-	-	-	S	-	-	-	ASCH
KIOEMHBE_02706	1.88e-111	-	-	-	K	-	-	-	GNAT family
KIOEMHBE_02707	2.14e-117	-	-	-	K	-	-	-	acetyltransferase
KIOEMHBE_02708	2.06e-30	-	-	-	-	-	-	-	-
KIOEMHBE_02709	5.05e-79	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
KIOEMHBE_02710	1.85e-208	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KIOEMHBE_02711	1.08e-243	-	-	-	-	-	-	-	-
KIOEMHBE_02712	2.07e-40	-	-	-	-	-	-	-	-
KIOEMHBE_02713	7.92e-140	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
KIOEMHBE_02714	5.93e-73	-	-	-	S	-	-	-	branched-chain amino acid
KIOEMHBE_02715	2.05e-167	-	-	-	E	-	-	-	branched-chain amino acid
KIOEMHBE_02716	1.6e-114	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
KIOEMHBE_02717	3.1e-304	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
KIOEMHBE_02718	5.61e-273	hpk31	-	-	T	-	-	-	Histidine kinase
KIOEMHBE_02719	1.14e-159	vanR	-	-	K	-	-	-	response regulator
KIOEMHBE_02720	2.4e-161	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
KIOEMHBE_02721	3.3e-208	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KIOEMHBE_02722	1.42e-269	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KIOEMHBE_02723	3.49e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
KIOEMHBE_02724	6.6e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KIOEMHBE_02725	1.4e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
KIOEMHBE_02726	7.16e-201	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
KIOEMHBE_02727	1.01e-175	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
KIOEMHBE_02728	8.63e-191	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
KIOEMHBE_02729	1.81e-168	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
KIOEMHBE_02730	4.76e-288	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
KIOEMHBE_02731	2.87e-270	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
KIOEMHBE_02732	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
KIOEMHBE_02733	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
KIOEMHBE_02734	1.25e-86	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
KIOEMHBE_02735	6.46e-221	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
KIOEMHBE_02736	1.04e-98	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
KIOEMHBE_02738	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
KIOEMHBE_02739	1.53e-26	-	-	-	-	-	-	-	-
KIOEMHBE_02740	4.95e-103	-	-	-	-	-	-	-	-
KIOEMHBE_02742	1.32e-224	-	-	-	M	-	-	-	Peptidase family S41
KIOEMHBE_02743	7.34e-124	-	-	-	K	-	-	-	Helix-turn-helix domain
KIOEMHBE_02744	5.05e-05	-	-	-	S	-	-	-	FRG
KIOEMHBE_02745	6.34e-39	-	-	-	-	-	-	-	-
KIOEMHBE_02746	1.4e-13	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KIOEMHBE_02747	7.1e-81	-	-	-	S	-	-	-	Protein of unknown function (DUF2992)
KIOEMHBE_02748	9.04e-78	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
KIOEMHBE_02749	1.11e-59	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
KIOEMHBE_02750	1.26e-137	-	-	-	L	-	-	-	Integrase
KIOEMHBE_02751	2.08e-60	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
KIOEMHBE_02752	3.03e-49	-	-	-	K	-	-	-	sequence-specific DNA binding
KIOEMHBE_02753	9.13e-70	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
KIOEMHBE_02754	2.78e-231	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
KIOEMHBE_02755	1.98e-72	repA	-	-	S	-	-	-	Replication initiator protein A
KIOEMHBE_02756	1.32e-57	-	-	-	-	-	-	-	-
KIOEMHBE_02757	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
KIOEMHBE_02758	1.96e-30	-	-	-	L	-	-	-	Initiator Replication protein
KIOEMHBE_02760	3.53e-38	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
KIOEMHBE_02761	1.92e-18	mpr	-	-	E	-	-	-	Trypsin-like serine protease
KIOEMHBE_02763	3.53e-65	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
KIOEMHBE_02764	2.63e-44	-	-	-	-	-	-	-	-
KIOEMHBE_02765	4.33e-162	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain protein
KIOEMHBE_02766	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
KIOEMHBE_02767	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
KIOEMHBE_02768	5.79e-08	-	-	-	-	-	-	-	-
KIOEMHBE_02769	8.94e-91	-	-	-	-	-	-	-	-
KIOEMHBE_02770	0.0	-	-	-	S	-	-	-	MucBP domain
KIOEMHBE_02771	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
KIOEMHBE_02772	4.33e-205	-	-	-	K	-	-	-	LysR substrate binding domain
KIOEMHBE_02773	1.85e-201	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
KIOEMHBE_02774	0.0	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
KIOEMHBE_02775	0.0	lepA2	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KIOEMHBE_02776	6.88e-152	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KIOEMHBE_02777	7.19e-89	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
KIOEMHBE_02778	9.45e-299	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
KIOEMHBE_02779	3.74e-302	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KIOEMHBE_02780	2.83e-206	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KIOEMHBE_02781	2.91e-190	malA	-	-	S	-	-	-	maltodextrose utilization protein MalA
KIOEMHBE_02782	0.0	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
KIOEMHBE_02783	2.44e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KIOEMHBE_02784	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
KIOEMHBE_02785	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
KIOEMHBE_02786	3.26e-102	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
KIOEMHBE_02787	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
KIOEMHBE_02788	2.66e-132	-	-	-	G	-	-	-	Glycogen debranching enzyme
KIOEMHBE_02789	5.6e-14	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
KIOEMHBE_02790	6.72e-208	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
KIOEMHBE_02791	2.02e-192	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
KIOEMHBE_02792	1.04e-94	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
KIOEMHBE_02793	1.1e-93	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
KIOEMHBE_02794	5.74e-32	-	-	-	-	-	-	-	-
KIOEMHBE_02795	1.37e-116	-	-	-	-	-	-	-	-
KIOEMHBE_02796	1.81e-50	ydaS	-	-	S	-	-	-	Transglycosylase associated protein
KIOEMHBE_02797	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase family
KIOEMHBE_02798	1.71e-59	-	-	-	S	-	-	-	MORN repeat
KIOEMHBE_02799	3.39e-52	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
KIOEMHBE_02800	5.3e-157	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
KIOEMHBE_02801	4.29e-101	-	-	-	-	-	-	-	-
KIOEMHBE_02802	5.09e-51	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
KIOEMHBE_02803	2.42e-127	-	-	-	FG	-	-	-	HIT domain
KIOEMHBE_02804	4.27e-223	ydhF	-	-	S	-	-	-	Aldo keto reductase
KIOEMHBE_02805	5.17e-70	-	-	-	S	-	-	-	Pfam:DUF59
KIOEMHBE_02806	4.56e-206	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KIOEMHBE_02807	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
KIOEMHBE_02808	1.87e-249	-	-	-	V	-	-	-	Beta-lactamase
KIOEMHBE_02809	3.74e-125	-	-	-	V	-	-	-	VanZ like family
KIOEMHBE_02810	6.02e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
KIOEMHBE_02811	7.81e-241	-	-	-	S	-	-	-	Cell surface protein
KIOEMHBE_02812	3.15e-98	-	-	-	-	-	-	-	-
KIOEMHBE_02813	0.0	-	-	-	-	-	-	-	-
KIOEMHBE_02814	3.56e-288	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
KIOEMHBE_02815	2.97e-51	-	-	-	S	ko:K07343	-	ko00000	TfoX C-terminal domain
KIOEMHBE_02816	2.81e-181	-	-	-	K	-	-	-	Helix-turn-helix domain
KIOEMHBE_02817	4.31e-179	-	-	-	-	-	-	-	-
KIOEMHBE_02818	2.82e-236	-	-	-	S	-	-	-	DUF218 domain
KIOEMHBE_02819	3.26e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KIOEMHBE_02820	9.06e-193	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
KIOEMHBE_02821	5.78e-292	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KIOEMHBE_02822	1.96e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
KIOEMHBE_02823	5.3e-49	-	-	-	-	-	-	-	-
KIOEMHBE_02824	2.95e-57	-	-	-	S	-	-	-	ankyrin repeats
KIOEMHBE_02825	5.13e-119	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
KIOEMHBE_02826	7.59e-64	-	-	-	-	-	-	-	-
KIOEMHBE_02827	6.83e-274	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
KIOEMHBE_02828	8.05e-178	-	-	-	F	-	-	-	NUDIX domain
KIOEMHBE_02829	2.68e-32	-	-	-	-	-	-	-	-
KIOEMHBE_02831	8.51e-209	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KIOEMHBE_02832	1.23e-222	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
KIOEMHBE_02833	3.43e-106	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
KIOEMHBE_02834	2.29e-48	-	-	-	-	-	-	-	-
KIOEMHBE_02835	4.54e-45	-	-	-	-	-	-	-	-
KIOEMHBE_02836	9.39e-277	-	-	-	T	-	-	-	diguanylate cyclase
KIOEMHBE_02838	2.55e-218	-	-	-	EG	-	-	-	EamA-like transporter family
KIOEMHBE_02839	1.06e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
KIOEMHBE_02840	2.12e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
KIOEMHBE_02841	1.45e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
KIOEMHBE_02842	0.0	yclK	-	-	T	-	-	-	Histidine kinase
KIOEMHBE_02843	5.23e-277	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
KIOEMHBE_02844	2.51e-200	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
KIOEMHBE_02845	6.66e-115	-	-	-	-	-	-	-	-
KIOEMHBE_02846	2.29e-225	-	-	-	L	-	-	-	Initiator Replication protein
KIOEMHBE_02847	3.67e-41	-	-	-	-	-	-	-	-
KIOEMHBE_02848	1.87e-139	-	-	-	L	-	-	-	Integrase
KIOEMHBE_02849	4.17e-55	-	-	-	K	-	-	-	prlF antitoxin for toxin YhaV_toxin
KIOEMHBE_02850	1.03e-77	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
KIOEMHBE_02851	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
KIOEMHBE_02853	8.81e-48	-	-	-	L	-	-	-	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KIOEMHBE_02854	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
KIOEMHBE_02855	3.1e-172	repA	-	-	S	-	-	-	Replication initiator protein A
KIOEMHBE_02856	1.95e-25	-	-	-	-	-	-	-	-
KIOEMHBE_02857	4.93e-54	-	-	-	-	-	-	-	-
KIOEMHBE_02858	1.39e-36	-	-	-	-	-	-	-	-
KIOEMHBE_02859	9.51e-142	XK27_07075	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
KIOEMHBE_02860	1.07e-74	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
KIOEMHBE_02861	2.13e-167	-	-	-	L	-	-	-	Helix-turn-helix domain
KIOEMHBE_02862	4.73e-206	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
KIOEMHBE_02863	6.16e-298	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
KIOEMHBE_02864	5.87e-51	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
KIOEMHBE_02865	1.01e-117	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
KIOEMHBE_02866	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
KIOEMHBE_02867	4.2e-22	-	-	-	-	-	-	-	-
KIOEMHBE_02868	1.54e-125	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KIOEMHBE_02869	2.1e-78	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
KIOEMHBE_02870	2.64e-129	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
KIOEMHBE_02871	2.43e-241	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
KIOEMHBE_02872	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
KIOEMHBE_02873	0.0	merA	1.16.1.1	-	C	ko:K00520,ko:K21739	-	ko00000,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KIOEMHBE_02874	2.78e-80	-	-	-	M	-	-	-	Cna protein B-type domain
KIOEMHBE_02875	1.61e-74	mleR	-	-	K	-	-	-	LysR substrate binding domain
KIOEMHBE_02876	3.55e-169	-	-	-	K	-	-	-	LysR family
KIOEMHBE_02877	0.0	-	-	-	C	-	-	-	FMN_bind
KIOEMHBE_02878	2.17e-304	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
KIOEMHBE_02879	3.99e-101	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
KIOEMHBE_02882	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
KIOEMHBE_02883	7.43e-130	padR	-	-	K	-	-	-	Virulence activator alpha C-term
KIOEMHBE_02884	2.51e-103	-	-	-	T	-	-	-	Universal stress protein family
KIOEMHBE_02885	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
KIOEMHBE_02887	7.39e-83	-	-	-	G	-	-	-	COG0662 Mannose-6-phosphate isomerase
KIOEMHBE_02888	2.85e-57	-	-	-	-	-	-	-	-
KIOEMHBE_02889	2.06e-66	ykoF	-	-	S	-	-	-	YKOF-related Family
KIOEMHBE_02890	5.63e-15	-	-	-	E	-	-	-	glutamine synthetase
KIOEMHBE_02891	9.73e-245	-	-	-	E	-	-	-	glutamine synthetase
KIOEMHBE_02892	3.2e-76	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
KIOEMHBE_02893	3.16e-59	-	-	-	T	ko:K07172	-	ko00000,ko02048	Antidote-toxin recognition MazE, bacterial antitoxin
KIOEMHBE_02894	9.24e-140	-	-	-	L	-	-	-	Integrase
KIOEMHBE_02895	3.72e-21	-	-	-	-	-	-	-	-
KIOEMHBE_02896	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
KIOEMHBE_02897	5.49e-237	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
KIOEMHBE_02898	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
KIOEMHBE_02900	2.37e-49	-	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
KIOEMHBE_02901	9.57e-315	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
KIOEMHBE_02902	7.8e-75	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
KIOEMHBE_02903	1.19e-124	-	-	-	L	-	-	-	Resolvase, N terminal domain
KIOEMHBE_02904	1.48e-81	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KIOEMHBE_02905	5.32e-298	aspD	4.1.1.12	-	E	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	ko00000,ko00001,ko01000	Aminotransferase class I and II
KIOEMHBE_02906	9.33e-249	-	-	-	U	ko:K07085	-	ko00000	Predicted Permease Membrane Region
KIOEMHBE_02907	6.47e-10	-	-	-	P	-	-	-	Cation efflux family
KIOEMHBE_02908	8.86e-35	-	-	-	-	-	-	-	-
KIOEMHBE_02909	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
KIOEMHBE_02910	2.44e-303	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
KIOEMHBE_02911	1.89e-71	-	-	-	-	-	-	-	-
KIOEMHBE_02912	7.86e-68	-	-	-	L	-	-	-	Transposase IS66 family
KIOEMHBE_02913	2.89e-256	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
KIOEMHBE_02914	3.9e-34	-	-	-	-	-	-	-	-
KIOEMHBE_02915	5.03e-75	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
KIOEMHBE_02916	4.16e-06	-	-	-	S	-	-	-	Transposase C of IS166 homeodomain
KIOEMHBE_02917	1.28e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Transcriptional regulator
KIOEMHBE_02918	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
KIOEMHBE_02919	9.4e-148	mdt(A)	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Major facilitator Superfamily
KIOEMHBE_02920	1.16e-84	-	-	-	-	-	-	-	-
KIOEMHBE_02921	2.09e-151	-	-	-	-	-	-	-	-
KIOEMHBE_02924	4.87e-45	-	-	-	-	-	-	-	-
KIOEMHBE_02925	8.69e-185	-	-	-	D	-	-	-	AAA domain
KIOEMHBE_02926	5.62e-49	kdpE	-	-	KT	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
KIOEMHBE_02927	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
KIOEMHBE_02928	1.74e-72	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
KIOEMHBE_02929	4.21e-174	bgaR	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
KIOEMHBE_02930	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
KIOEMHBE_02931	5.17e-70	-	-	-	S	-	-	-	Nitroreductase
KIOEMHBE_02932	4.31e-196	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
KIOEMHBE_02933	1.39e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KIOEMHBE_02934	3.23e-150	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
KIOEMHBE_02935	4.27e-146	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
KIOEMHBE_02936	3.79e-26	-	-	-	-	-	-	-	-
KIOEMHBE_02937	5.41e-89	-	-	-	C	-	-	-	lyase activity
KIOEMHBE_02938	3.77e-278	-	-	-	EGP	-	-	-	Major Facilitator
KIOEMHBE_02939	1.62e-150	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
KIOEMHBE_02940	8.61e-19	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	adenosylhomocysteinase activity
KIOEMHBE_02941	2.44e-54	-	-	-	-	-	-	-	-
KIOEMHBE_02943	6.89e-190	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
KIOEMHBE_02944	1.95e-62	-	-	-	S	-	-	-	Family of unknown function (DUF5388)
KIOEMHBE_02946	7.57e-122	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KIOEMHBE_02947	3.47e-244	-	1.1.1.219	-	GM	ko:K00091	-	ko00000,ko01000	Male sterility protein
KIOEMHBE_02948	1.27e-129	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
KIOEMHBE_02949	1.34e-34	-	-	-	-	-	-	-	-
KIOEMHBE_02950	8.5e-55	-	-	-	-	-	-	-	-
KIOEMHBE_02951	6.45e-111	-	-	-	-	-	-	-	-
KIOEMHBE_02952	2.83e-58	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
KIOEMHBE_02953	2.62e-160	-	-	-	S	-	-	-	Phage Mu protein F like protein
KIOEMHBE_02954	3.62e-22	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
KIOEMHBE_02955	9.4e-122	-	-	-	L	-	-	-	4.5 Transposon and IS
KIOEMHBE_02956	1.15e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase
KIOEMHBE_02958	6.03e-36	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KIOEMHBE_02959	3.11e-17	-	-	-	S	-	-	-	protein with an alpha beta hydrolase fold
KIOEMHBE_02960	2.03e-31	-	-	-	S	-	-	-	Family of unknown function (DUF5388)
KIOEMHBE_02961	1.18e-184	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
KIOEMHBE_02963	6.13e-127	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
KIOEMHBE_02964	6.04e-43	-	-	-	-	-	-	-	-
KIOEMHBE_02965	1.74e-18	-	-	-	Q	-	-	-	Methyltransferase
KIOEMHBE_02966	1.18e-192	degV	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
KIOEMHBE_02967	9.51e-135	-	-	-	-	-	-	-	-
KIOEMHBE_02968	3.72e-14	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
KIOEMHBE_02969	1.32e-107	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
KIOEMHBE_02970	2.26e-39	-	-	-	L	-	-	-	manually curated
KIOEMHBE_02971	2.67e-75	-	-	-	-	-	-	-	-
KIOEMHBE_02972	2.54e-42	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
KIOEMHBE_02973	4.19e-54	-	-	-	-	-	-	-	-
KIOEMHBE_02974	1.18e-194	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
KIOEMHBE_02975	1.41e-163	-	-	-	P	-	-	-	integral membrane protein, YkoY family
KIOEMHBE_02977	3.47e-47	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
KIOEMHBE_02978	4.05e-211	-	-	-	L	-	-	-	PFAM Integrase catalytic region
KIOEMHBE_02979	8.72e-163	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
KIOEMHBE_02980	2.43e-91	-	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
KIOEMHBE_02981	3.55e-76	-	-	-	-	-	-	-	-
KIOEMHBE_02982	6.01e-49	-	-	-	S	-	-	-	Bacteriophage holin
KIOEMHBE_02983	2.58e-147	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KIOEMHBE_02985	4.64e-18	-	-	-	-	-	-	-	-
KIOEMHBE_02987	1.95e-114	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
KIOEMHBE_02988	3.76e-115	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
KIOEMHBE_02989	8.37e-108	-	-	-	L	-	-	-	Transposase DDE domain
KIOEMHBE_02990	2.69e-105	-	-	-	L	ko:K07498	-	ko00000	DDE domain
KIOEMHBE_02991	1.99e-40	-	-	-	L	-	-	-	RePlication protein