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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HMCAHBCO_00002	2.16e-208	-	-	-	K	-	-	-	Transcriptional regulator
HMCAHBCO_00003	2.43e-206	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HMCAHBCO_00004	1.66e-211	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
HMCAHBCO_00005	5.73e-100	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HMCAHBCO_00006	0.0	ycaM	-	-	E	-	-	-	amino acid
HMCAHBCO_00007	2.38e-164	aroC1	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
HMCAHBCO_00008	4.3e-44	-	-	-	-	-	-	-	-
HMCAHBCO_00009	0.0	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HMCAHBCO_00010	9.78e-187	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HMCAHBCO_00011	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HMCAHBCO_00012	4.75e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HMCAHBCO_00013	0.0	-	-	-	-	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	-
HMCAHBCO_00014	1.54e-131	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HMCAHBCO_00015	1.96e-224	serA1	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HMCAHBCO_00016	3.98e-204	-	-	-	EG	-	-	-	EamA-like transporter family
HMCAHBCO_00017	6.86e-232	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HMCAHBCO_00018	5.06e-196	-	-	-	S	-	-	-	hydrolase
HMCAHBCO_00019	7.63e-107	-	-	-	-	-	-	-	-
HMCAHBCO_00020	1.75e-156	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
HMCAHBCO_00021	1.4e-181	epsV	-	-	S	-	-	-	glycosyl transferase family 2
HMCAHBCO_00022	1.23e-166	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HMCAHBCO_00023	1.86e-64	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HMCAHBCO_00024	6.7e-74	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
HMCAHBCO_00025	0.0	pbg5	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HMCAHBCO_00026	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HMCAHBCO_00027	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HMCAHBCO_00028	4.29e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HMCAHBCO_00029	9.24e-231	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HMCAHBCO_00030	6.09e-152	-	-	-	K	-	-	-	Transcriptional regulator
HMCAHBCO_00031	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMCAHBCO_00032	7.54e-115	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
HMCAHBCO_00033	4.43e-294	-	-	-	S	-	-	-	Sterol carrier protein domain
HMCAHBCO_00034	2.45e-269	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HMCAHBCO_00035	3.25e-48	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
HMCAHBCO_00036	5.41e-172	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HMCAHBCO_00037	2.26e-91	-	-	-	FG	-	-	-	Scavenger mRNA decapping enzyme C-term binding
HMCAHBCO_00038	1.13e-132	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HMCAHBCO_00039	5.88e-142	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HMCAHBCO_00040	2.99e-38	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
HMCAHBCO_00041	4.65e-186	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HMCAHBCO_00042	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HMCAHBCO_00043	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HMCAHBCO_00045	1.21e-69	-	-	-	-	-	-	-	-
HMCAHBCO_00046	1.52e-151	-	-	-	-	-	-	-	-
HMCAHBCO_00047	1.16e-110	-	-	-	F	-	-	-	belongs to the nudix hydrolase family
HMCAHBCO_00048	3.03e-299	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HMCAHBCO_00049	4.79e-13	-	-	-	-	-	-	-	-
HMCAHBCO_00050	5.92e-67	-	-	-	-	-	-	-	-
HMCAHBCO_00051	1.76e-114	-	-	-	-	-	-	-	-
HMCAHBCO_00052	5.7e-95	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HMCAHBCO_00053	3.64e-46	-	-	-	-	-	-	-	-
HMCAHBCO_00054	1.1e-103	usp5	-	-	T	-	-	-	universal stress protein
HMCAHBCO_00055	4.21e-175	-	-	-	-	-	-	-	-
HMCAHBCO_00056	7.89e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMCAHBCO_00057	8.2e-81	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HMCAHBCO_00058	1.87e-53	-	-	-	-	-	-	-	-
HMCAHBCO_00059	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HMCAHBCO_00060	2.05e-178	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMCAHBCO_00061	3.7e-233	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HMCAHBCO_00062	6.89e-190	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HMCAHBCO_00063	5.95e-153	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
HMCAHBCO_00064	4.81e-188	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HMCAHBCO_00065	5.76e-243	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
HMCAHBCO_00066	9.92e-143	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HMCAHBCO_00067	4.57e-304	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HMCAHBCO_00068	3.77e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HMCAHBCO_00069	2.87e-270	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HMCAHBCO_00070	3.39e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HMCAHBCO_00071	1.17e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMCAHBCO_00072	6.91e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMCAHBCO_00073	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMCAHBCO_00074	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HMCAHBCO_00075	4.22e-243	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HMCAHBCO_00076	5.35e-133	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HMCAHBCO_00077	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HMCAHBCO_00078	9.06e-279	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HMCAHBCO_00079	1.83e-157	-	-	-	E	-	-	-	Methionine synthase
HMCAHBCO_00080	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HMCAHBCO_00081	1.85e-121	-	-	-	-	-	-	-	-
HMCAHBCO_00082	1.25e-199	-	-	-	T	-	-	-	EAL domain
HMCAHBCO_00083	2.24e-206	-	-	-	GM	-	-	-	NmrA-like family
HMCAHBCO_00084	5.67e-280	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
HMCAHBCO_00085	3.1e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HMCAHBCO_00086	0.0	pucR_2	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
HMCAHBCO_00087	7.13e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HMCAHBCO_00088	2.02e-219	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HMCAHBCO_00089	1.61e-308	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HMCAHBCO_00090	2.76e-271	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HMCAHBCO_00091	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HMCAHBCO_00092	1.04e-218	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HMCAHBCO_00093	1.55e-161	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HMCAHBCO_00094	5.46e-145	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HMCAHBCO_00095	1.12e-216	oroP	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
HMCAHBCO_00096	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HMCAHBCO_00097	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HMCAHBCO_00098	3.86e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HMCAHBCO_00099	1.29e-148	-	-	-	GM	-	-	-	NAD(P)H-binding
HMCAHBCO_00100	6.68e-207	mleR	-	-	K	-	-	-	LysR family
HMCAHBCO_00101	2.09e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HMCAHBCO_00102	3.59e-26	-	-	-	-	-	-	-	-
HMCAHBCO_00103	1.84e-204	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HMCAHBCO_00104	1.02e-277	araT2	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HMCAHBCO_00105	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	Bacterial regulatory proteins, gntR family
HMCAHBCO_00106	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HMCAHBCO_00107	4.71e-74	-	-	-	S	-	-	-	SdpI/YhfL protein family
HMCAHBCO_00108	4.68e-161	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HMCAHBCO_00109	9.75e-39	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HMCAHBCO_00110	3.45e-83	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HMCAHBCO_00111	2.03e-271	yttB	-	-	EGP	-	-	-	Major Facilitator
HMCAHBCO_00112	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HMCAHBCO_00113	1.18e-114	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HMCAHBCO_00114	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HMCAHBCO_00115	2.97e-76	-	-	-	-	-	-	-	-
HMCAHBCO_00116	2.61e-96	hsp2	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HMCAHBCO_00117	1.55e-79	-	-	-	-	-	-	-	-
HMCAHBCO_00118	1.7e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HMCAHBCO_00119	8.05e-179	rrp8	-	-	K	-	-	-	LytTr DNA-binding domain
HMCAHBCO_00120	1.97e-150	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HMCAHBCO_00121	2.48e-178	-	-	-	-	-	-	-	-
HMCAHBCO_00122	4.75e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HMCAHBCO_00123	3.53e-169	-	-	-	K	-	-	-	Transcriptional regulator
HMCAHBCO_00124	2.01e-209	-	-	-	S	-	-	-	Putative esterase
HMCAHBCO_00125	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HMCAHBCO_00126	1.25e-283	-	-	-	M	-	-	-	Glycosyl transferases group 1
HMCAHBCO_00127	1.38e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HMCAHBCO_00128	4.05e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HMCAHBCO_00129	2.5e-203	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HMCAHBCO_00130	2.51e-103	uspA3	-	-	T	-	-	-	universal stress protein
HMCAHBCO_00131	0.0	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
HMCAHBCO_00132	4.26e-250	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HMCAHBCO_00133	4.15e-78	-	-	-	-	-	-	-	-
HMCAHBCO_00134	1.65e-97	-	-	-	-	-	-	-	-
HMCAHBCO_00135	6.94e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2798)
HMCAHBCO_00136	2.57e-70	-	-	-	-	-	-	-	-
HMCAHBCO_00137	3.89e-62	-	-	-	-	-	-	-	-
HMCAHBCO_00138	3.87e-262	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HMCAHBCO_00139	9.89e-74	ytpP	-	-	CO	-	-	-	Thioredoxin
HMCAHBCO_00140	1.19e-186	-	-	-	S	ko:K06889	-	ko00000	Dienelactone hydrolase family
HMCAHBCO_00141	1.83e-37	-	-	-	-	-	-	-	-
HMCAHBCO_00142	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HMCAHBCO_00143	2.8e-63	-	-	-	-	-	-	-	-
HMCAHBCO_00144	1.23e-75	-	-	-	-	-	-	-	-
HMCAHBCO_00145	1.86e-210	-	-	-	-	-	-	-	-
HMCAHBCO_00146	1.4e-95	-	-	-	K	-	-	-	Transcriptional regulator
HMCAHBCO_00147	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
HMCAHBCO_00148	8.94e-221	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HMCAHBCO_00149	7.2e-61	-	-	-	S	-	-	-	Enterocin A Immunity
HMCAHBCO_00150	8.34e-86	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
HMCAHBCO_00151	1.01e-161	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HMCAHBCO_00152	2.66e-172	-	-	-	-	-	-	-	-
HMCAHBCO_00153	9.38e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
HMCAHBCO_00154	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HMCAHBCO_00155	0.0	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HMCAHBCO_00156	8.97e-253	yhhX	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HMCAHBCO_00157	2.48e-227	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HMCAHBCO_00158	5.91e-150	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HMCAHBCO_00159	1.48e-201	ccpB	-	-	K	-	-	-	lacI family
HMCAHBCO_00160	2.2e-157	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HMCAHBCO_00161	3.68e-203	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMCAHBCO_00162	5.02e-228	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HMCAHBCO_00163	3e-127	-	-	-	C	-	-	-	Nitroreductase family
HMCAHBCO_00164	6.04e-217	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HMCAHBCO_00165	2.14e-183	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HMCAHBCO_00166	2.71e-234	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HMCAHBCO_00167	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HMCAHBCO_00168	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HMCAHBCO_00169	6.05e-98	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HMCAHBCO_00170	1.78e-279	-	-	-	M	-	-	-	domain protein
HMCAHBCO_00171	6.32e-67	-	-	-	M	-	-	-	domain protein
HMCAHBCO_00172	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HMCAHBCO_00173	1.06e-145	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HMCAHBCO_00174	1.45e-46	-	-	-	-	-	-	-	-
HMCAHBCO_00175	5.48e-236	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HMCAHBCO_00176	1.97e-254	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HMCAHBCO_00177	4.54e-126	-	-	-	J	-	-	-	glyoxalase III activity
HMCAHBCO_00178	1.01e-189	-	-	-	GM	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HMCAHBCO_00179	4.73e-118	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
HMCAHBCO_00180	6.7e-74	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HMCAHBCO_00181	7.28e-213	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HMCAHBCO_00182	3.72e-283	ysaA	-	-	V	-	-	-	RDD family
HMCAHBCO_00183	4.54e-208	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
HMCAHBCO_00184	2.3e-275	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HMCAHBCO_00185	1.69e-151	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HMCAHBCO_00186	7.8e-299	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HMCAHBCO_00187	2.46e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HMCAHBCO_00188	2.23e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HMCAHBCO_00189	5.62e-165	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HMCAHBCO_00190	1.27e-172	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HMCAHBCO_00191	6.12e-78	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HMCAHBCO_00192	1.07e-68	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
HMCAHBCO_00193	1.9e-258	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HMCAHBCO_00194	2.47e-125	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HMCAHBCO_00195	1.18e-175	yceF	-	-	P	ko:K05794	-	ko00000	membrane
HMCAHBCO_00196	9.51e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
HMCAHBCO_00197	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HMCAHBCO_00198	1.32e-178	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMCAHBCO_00199	6.03e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HMCAHBCO_00200	9.31e-225	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HMCAHBCO_00201	1.53e-213	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HMCAHBCO_00202	6.08e-312	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HMCAHBCO_00203	6.83e-292	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HMCAHBCO_00204	3.45e-209	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HMCAHBCO_00205	1.31e-242	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HMCAHBCO_00206	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HMCAHBCO_00207	2.64e-61	-	-	-	-	-	-	-	-
HMCAHBCO_00208	2.35e-106	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMCAHBCO_00209	9.24e-140	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HMCAHBCO_00210	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HMCAHBCO_00211	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HMCAHBCO_00212	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HMCAHBCO_00213	2.18e-182	ybbR	-	-	S	-	-	-	YbbR-like protein
HMCAHBCO_00214	2.39e-191	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HMCAHBCO_00215	8.06e-156	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
HMCAHBCO_00216	3.07e-119	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HMCAHBCO_00217	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HMCAHBCO_00218	6.24e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HMCAHBCO_00219	3.09e-213	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
HMCAHBCO_00220	2.53e-198	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HMCAHBCO_00221	2.41e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HMCAHBCO_00222	2.52e-114	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HMCAHBCO_00223	1.29e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HMCAHBCO_00224	1.23e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HMCAHBCO_00225	1.4e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HMCAHBCO_00226	1.98e-199	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HMCAHBCO_00227	7.98e-137	-	-	-	-	-	-	-	-
HMCAHBCO_00228	9.36e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HMCAHBCO_00229	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMCAHBCO_00230	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HMCAHBCO_00231	2.4e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HMCAHBCO_00232	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HMCAHBCO_00233	3.83e-179	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
HMCAHBCO_00234	3.55e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HMCAHBCO_00235	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HMCAHBCO_00236	2.83e-168	-	-	-	-	-	-	-	-
HMCAHBCO_00237	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HMCAHBCO_00238	7.15e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HMCAHBCO_00239	1.31e-285	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HMCAHBCO_00240	2.02e-245	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HMCAHBCO_00241	5.75e-242	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HMCAHBCO_00242	1.14e-311	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
HMCAHBCO_00244	5.11e-133	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HMCAHBCO_00245	8.58e-223	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMCAHBCO_00246	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HMCAHBCO_00247	1.21e-215	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HMCAHBCO_00248	5.32e-242	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HMCAHBCO_00249	1.71e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HMCAHBCO_00250	3.51e-113	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HMCAHBCO_00251	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HMCAHBCO_00252	7.5e-302	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HMCAHBCO_00253	2.21e-113	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HMCAHBCO_00254	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HMCAHBCO_00255	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HMCAHBCO_00256	3.85e-151	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HMCAHBCO_00257	5.33e-268	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
HMCAHBCO_00258	1.89e-134	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HMCAHBCO_00259	0.0	nox2	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HMCAHBCO_00260	5.9e-170	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HMCAHBCO_00261	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HMCAHBCO_00262	7.54e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HMCAHBCO_00263	4.31e-141	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HMCAHBCO_00264	8.65e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HMCAHBCO_00265	0.0	nox	-	-	C	-	-	-	NADH oxidase
HMCAHBCO_00266	6.37e-160	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HMCAHBCO_00267	1.13e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HMCAHBCO_00268	4e-235	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HMCAHBCO_00269	6.26e-213	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HMCAHBCO_00270	2.55e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HMCAHBCO_00271	2.87e-71	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HMCAHBCO_00272	2.78e-65	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
HMCAHBCO_00273	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HMCAHBCO_00274	4.47e-177	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMCAHBCO_00275	9.78e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMCAHBCO_00276	5.04e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HMCAHBCO_00277	9.05e-206	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HMCAHBCO_00278	2.31e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HMCAHBCO_00279	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HMCAHBCO_00280	1.49e-170	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HMCAHBCO_00281	1.05e-275	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HMCAHBCO_00282	3.41e-257	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HMCAHBCO_00283	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HMCAHBCO_00284	1.27e-129	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HMCAHBCO_00285	2.94e-164	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HMCAHBCO_00286	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HMCAHBCO_00287	3.7e-149	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HMCAHBCO_00288	6.57e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HMCAHBCO_00289	7.29e-247	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
HMCAHBCO_00290	0.0	ydaO	-	-	E	-	-	-	amino acid
HMCAHBCO_00291	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HMCAHBCO_00292	9.82e-55	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HMCAHBCO_00293	2.38e-140	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HMCAHBCO_00294	3.67e-154	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HMCAHBCO_00295	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HMCAHBCO_00296	3.62e-249	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HMCAHBCO_00297	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HMCAHBCO_00298	4.66e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HMCAHBCO_00299	6.84e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HMCAHBCO_00300	3.46e-242	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HMCAHBCO_00301	3.8e-176	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HMCAHBCO_00302	2.18e-176	phnE2	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter permease
HMCAHBCO_00303	3.33e-184	phnE1	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HMCAHBCO_00304	2.8e-187	phnX	3.11.1.1	-	E	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the HAD-like hydrolase superfamily. PhnX family
HMCAHBCO_00305	5.35e-270	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HMCAHBCO_00306	4.95e-246	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HMCAHBCO_00307	1.29e-190	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HMCAHBCO_00308	2.64e-213	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HMCAHBCO_00309	8.46e-77	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HMCAHBCO_00310	2.33e-239	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HMCAHBCO_00311	1.39e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HMCAHBCO_00312	1.82e-152	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HMCAHBCO_00313	1.01e-51	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HMCAHBCO_00314	6.22e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HMCAHBCO_00315	8.34e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HMCAHBCO_00316	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMCAHBCO_00317	7.57e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HMCAHBCO_00318	6.7e-141	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HMCAHBCO_00319	8.42e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HMCAHBCO_00320	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMCAHBCO_00321	2.47e-253	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMCAHBCO_00322	2.37e-140	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HMCAHBCO_00323	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HMCAHBCO_00324	4.82e-86	-	-	-	L	-	-	-	nuclease
HMCAHBCO_00325	1.01e-226	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HMCAHBCO_00326	2.76e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HMCAHBCO_00327	3.72e-105	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HMCAHBCO_00328	2.69e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HMCAHBCO_00329	9.76e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HMCAHBCO_00330	2.81e-202	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HMCAHBCO_00331	1.89e-128	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HMCAHBCO_00332	1e-39	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HMCAHBCO_00333	4.55e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HMCAHBCO_00334	1.12e-130	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
HMCAHBCO_00335	1.44e-125	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
HMCAHBCO_00336	1.49e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMCAHBCO_00337	1.35e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HMCAHBCO_00338	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HMCAHBCO_00339	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HMCAHBCO_00340	4.91e-265	yacL	-	-	S	-	-	-	domain protein
HMCAHBCO_00341	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HMCAHBCO_00342	9.43e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HMCAHBCO_00343	5.96e-69	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HMCAHBCO_00344	1.62e-158	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HMCAHBCO_00345	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HMCAHBCO_00346	3.22e-147	zmp2	-	-	O	-	-	-	Zinc-dependent metalloprotease
HMCAHBCO_00347	1.91e-165	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMCAHBCO_00348	1.22e-226	-	-	-	EG	-	-	-	EamA-like transporter family
HMCAHBCO_00349	3.06e-214	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HMCAHBCO_00350	5.37e-233	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HMCAHBCO_00351	1.05e-172	accA1	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
HMCAHBCO_00352	1.49e-183	accD1	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HMCAHBCO_00353	1.7e-315	accC1	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
HMCAHBCO_00354	9.24e-85	accB1	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin-requiring enzyme
HMCAHBCO_00355	3.15e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HMCAHBCO_00356	4.5e-113	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HMCAHBCO_00357	4.16e-93	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HMCAHBCO_00358	0.0	levR	-	-	K	-	-	-	Sigma-54 interaction domain
HMCAHBCO_00359	9.05e-85	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
HMCAHBCO_00360	4.22e-216	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HMCAHBCO_00361	4.51e-172	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HMCAHBCO_00362	6.46e-218	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HMCAHBCO_00363	1.53e-195	-	-	-	G	-	-	-	Peptidase_C39 like family
HMCAHBCO_00365	1.9e-198	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HMCAHBCO_00366	1.71e-302	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HMCAHBCO_00367	3.09e-106	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HMCAHBCO_00368	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HMCAHBCO_00369	2.57e-94	-	-	-	-	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	-
HMCAHBCO_00370	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HMCAHBCO_00371	1.51e-196	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HMCAHBCO_00372	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMCAHBCO_00373	5.44e-175	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HMCAHBCO_00374	5.41e-160	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HMCAHBCO_00375	2.92e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HMCAHBCO_00376	2.18e-174	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HMCAHBCO_00377	1.06e-195	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HMCAHBCO_00378	1.59e-247	ysdE	-	-	P	-	-	-	Citrate transporter
HMCAHBCO_00379	3.1e-212	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
HMCAHBCO_00380	1.38e-71	-	-	-	S	-	-	-	Cupin domain
HMCAHBCO_00381	9.02e-66	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
HMCAHBCO_00385	1.75e-193	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HMCAHBCO_00386	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HMCAHBCO_00388	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HMCAHBCO_00389	2.92e-118	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HMCAHBCO_00390	9.16e-190	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HMCAHBCO_00391	5.09e-81	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
HMCAHBCO_00392	4.61e-222	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HMCAHBCO_00393	3.79e-57	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HMCAHBCO_00394	4.85e-119	XK27_09665	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
HMCAHBCO_00395	0.0	-	-	-	M	-	-	-	MucBP domain
HMCAHBCO_00396	5.1e-315	-	-	-	M	-	-	-	MucBP domain
HMCAHBCO_00397	1.42e-08	-	-	-	-	-	-	-	-
HMCAHBCO_00398	1.73e-113	-	-	-	S	-	-	-	AAA domain
HMCAHBCO_00399	7.45e-180	-	-	-	K	-	-	-	sequence-specific DNA binding
HMCAHBCO_00400	2.56e-60	-	-	-	K	-	-	-	Helix-turn-helix domain
HMCAHBCO_00401	7.39e-54	-	-	-	K	-	-	-	Helix-turn-helix domain
HMCAHBCO_00402	3.93e-220	-	-	-	K	-	-	-	Transcriptional regulator
HMCAHBCO_00403	4.37e-120	-	-	-	C	-	-	-	FMN_bind
HMCAHBCO_00404	5.68e-266	-	-	-	C	-	-	-	FMN_bind
HMCAHBCO_00406	4.3e-106	-	-	-	K	-	-	-	Transcriptional regulator
HMCAHBCO_00407	1.64e-149	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HMCAHBCO_00408	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HMCAHBCO_00409	3.39e-255	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HMCAHBCO_00410	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HMCAHBCO_00411	1.32e-290	-	-	-	L	-	-	-	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HMCAHBCO_00412	9.05e-55	-	-	-	-	-	-	-	-
HMCAHBCO_00413	4.95e-44	-	-	-	L	-	-	-	leucine-zipper of insertion element IS481
HMCAHBCO_00414	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HMCAHBCO_00415	9.95e-211	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HMCAHBCO_00416	5.06e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HMCAHBCO_00417	2.91e-179	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HMCAHBCO_00418	2.26e-243	-	-	-	-	-	-	-	-
HMCAHBCO_00419	1.89e-277	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HMCAHBCO_00420	4.18e-163	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HMCAHBCO_00421	7.84e-117	-	-	-	K	-	-	-	FR47-like protein
HMCAHBCO_00422	1.24e-155	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
HMCAHBCO_00423	3.33e-64	-	-	-	-	-	-	-	-
HMCAHBCO_00424	4.24e-246	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HMCAHBCO_00425	0.0	xylP2	-	-	G	-	-	-	symporter
HMCAHBCO_00426	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HMCAHBCO_00427	9.85e-281	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HMCAHBCO_00428	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HMCAHBCO_00429	3.43e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HMCAHBCO_00430	2.03e-155	azlC	-	-	E	-	-	-	branched-chain amino acid
HMCAHBCO_00431	1.75e-47	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HMCAHBCO_00432	1.46e-170	-	-	-	-	-	-	-	-
HMCAHBCO_00433	2.72e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HMCAHBCO_00434	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HMCAHBCO_00435	7.79e-112	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HMCAHBCO_00436	1.36e-77	-	-	-	-	-	-	-	-
HMCAHBCO_00437	2.94e-155	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HMCAHBCO_00438	1.78e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HMCAHBCO_00439	4.6e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
HMCAHBCO_00440	7.76e-100	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HMCAHBCO_00441	2.34e-242	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HMCAHBCO_00442	4.15e-153	-	-	-	I	-	-	-	phosphatase
HMCAHBCO_00443	3.88e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HMCAHBCO_00444	3.03e-129	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HMCAHBCO_00445	5.68e-117	-	-	-	K	-	-	-	Transcriptional regulator
HMCAHBCO_00446	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HMCAHBCO_00447	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HMCAHBCO_00448	7.48e-153	dacB	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HMCAHBCO_00449	1.11e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HMCAHBCO_00450	1.62e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HMCAHBCO_00457	9.78e-102	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HMCAHBCO_00458	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HMCAHBCO_00459	1.16e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMCAHBCO_00460	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMCAHBCO_00461	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMCAHBCO_00462	1.48e-149	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HMCAHBCO_00463	4.19e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HMCAHBCO_00464	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HMCAHBCO_00465	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HMCAHBCO_00466	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HMCAHBCO_00467	1.24e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HMCAHBCO_00468	9.83e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HMCAHBCO_00469	2.27e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HMCAHBCO_00470	6.61e-193	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HMCAHBCO_00471	1.85e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HMCAHBCO_00472	3.59e-69	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HMCAHBCO_00473	5.46e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HMCAHBCO_00474	8.29e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HMCAHBCO_00475	1.11e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HMCAHBCO_00476	1.96e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HMCAHBCO_00477	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HMCAHBCO_00478	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HMCAHBCO_00479	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HMCAHBCO_00480	4.99e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HMCAHBCO_00481	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HMCAHBCO_00482	1.75e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HMCAHBCO_00483	5.32e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HMCAHBCO_00484	8.44e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HMCAHBCO_00485	1.32e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HMCAHBCO_00486	5.95e-300	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HMCAHBCO_00487	1.84e-160	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HMCAHBCO_00488	9.87e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HMCAHBCO_00489	9.65e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HMCAHBCO_00490	7.71e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HMCAHBCO_00491	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMCAHBCO_00492	7.76e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HMCAHBCO_00493	1.02e-233	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HMCAHBCO_00494	1.41e-122	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
HMCAHBCO_00495	4.42e-111	-	-	-	S	-	-	-	NusG domain II
HMCAHBCO_00496	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HMCAHBCO_00497	3.19e-194	-	-	-	S	-	-	-	FMN_bind
HMCAHBCO_00498	3.08e-264	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HMCAHBCO_00499	1.98e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMCAHBCO_00500	2.01e-211	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMCAHBCO_00501	2.29e-182	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMCAHBCO_00502	3.06e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HMCAHBCO_00503	4.58e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HMCAHBCO_00504	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HMCAHBCO_00505	8.51e-210	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HMCAHBCO_00506	1.68e-221	-	-	-	S	-	-	-	Membrane
HMCAHBCO_00507	9.14e-38	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HMCAHBCO_00508	2.99e-208	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HMCAHBCO_00509	0.0	tkt2	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HMCAHBCO_00510	1.65e-211	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HMCAHBCO_00511	3.3e-235	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	DAHP synthetase I family
HMCAHBCO_00512	1.33e-255	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HMCAHBCO_00514	1.49e-281	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HMCAHBCO_00515	1.51e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HMCAHBCO_00516	1.41e-147	-	4.2.1.2, 4.2.1.32	-	C	ko:K01676,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
HMCAHBCO_00517	4.28e-225	ttdA	4.2.1.32	-	C	ko:K03779	ko00630,map00630	ko00000,ko00001,ko01000	Fumarate hydratase (Fumerase)
HMCAHBCO_00518	6.07e-252	-	-	-	K	-	-	-	Helix-turn-helix domain
HMCAHBCO_00519	3.16e-196	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HMCAHBCO_00520	2.04e-170	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HMCAHBCO_00521	1.76e-180	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HMCAHBCO_00522	4.26e-222	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HMCAHBCO_00523	1.18e-66	-	-	-	-	-	-	-	-
HMCAHBCO_00524	9.2e-215	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HMCAHBCO_00525	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HMCAHBCO_00526	8.69e-230	citR	-	-	K	-	-	-	sugar-binding domain protein
HMCAHBCO_00527	1.11e-263	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
HMCAHBCO_00528	3.07e-241	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HMCAHBCO_00529	1.23e-58	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
HMCAHBCO_00530	1.51e-206	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
HMCAHBCO_00531	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
HMCAHBCO_00532	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HMCAHBCO_00533	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HMCAHBCO_00534	2.32e-121	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HMCAHBCO_00535	4.54e-207	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
HMCAHBCO_00536	1.53e-213	mleR	-	-	K	-	-	-	LysR family
HMCAHBCO_00537	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HMCAHBCO_00538	2.6e-212	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
HMCAHBCO_00539	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HMCAHBCO_00540	4.37e-128	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HMCAHBCO_00541	6.07e-33	-	-	-	-	-	-	-	-
HMCAHBCO_00542	0.0	-	-	-	S	ko:K06889	-	ko00000	Alpha beta
HMCAHBCO_00543	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HMCAHBCO_00544	7.76e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HMCAHBCO_00545	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HMCAHBCO_00546	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HMCAHBCO_00547	1.89e-208	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HMCAHBCO_00548	4.87e-234	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HMCAHBCO_00549	4.92e-212	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HMCAHBCO_00550	7.17e-62	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HMCAHBCO_00551	2.15e-07	-	-	-	K	-	-	-	transcriptional regulator
HMCAHBCO_00552	5.58e-274	-	-	-	S	-	-	-	membrane
HMCAHBCO_00553	1.51e-105	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMCAHBCO_00554	0.0	-	-	-	S	-	-	-	Zinc finger, swim domain protein
HMCAHBCO_00555	8.09e-146	-	-	-	GM	-	-	-	epimerase
HMCAHBCO_00556	6.34e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
HMCAHBCO_00557	2.65e-93	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
HMCAHBCO_00558	1.4e-137	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HMCAHBCO_00559	1.68e-176	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HMCAHBCO_00560	0.0	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HMCAHBCO_00561	1.3e-264	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HMCAHBCO_00562	4.38e-102	-	-	-	K	-	-	-	Transcriptional regulator
HMCAHBCO_00563	4.6e-307	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
HMCAHBCO_00564	1.27e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HMCAHBCO_00565	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HMCAHBCO_00566	1.68e-229	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HMCAHBCO_00567	4.8e-278	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HMCAHBCO_00568	1.93e-266	-	-	-	-	-	-	-	-
HMCAHBCO_00569	6.11e-118	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HMCAHBCO_00570	2.65e-81	-	-	-	P	-	-	-	Rhodanese Homology Domain
HMCAHBCO_00571	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HMCAHBCO_00572	2.74e-112	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HMCAHBCO_00573	2.08e-213	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HMCAHBCO_00574	2.52e-165	drrB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HMCAHBCO_00575	1.75e-295	-	-	-	M	-	-	-	O-Antigen ligase
HMCAHBCO_00576	6.85e-164	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HMCAHBCO_00577	1.09e-249	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HMCAHBCO_00578	1.29e-298	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HMCAHBCO_00579	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HMCAHBCO_00581	7.03e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HMCAHBCO_00582	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HMCAHBCO_00583	8.69e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HMCAHBCO_00584	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HMCAHBCO_00585	2.51e-98	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
HMCAHBCO_00586	4.59e-217	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HMCAHBCO_00587	3.13e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HMCAHBCO_00588	3.99e-92	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMCAHBCO_00589	7.1e-176	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HMCAHBCO_00590	1.3e-132	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HMCAHBCO_00591	2.69e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HMCAHBCO_00592	2.24e-126	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HMCAHBCO_00593	3.38e-252	-	-	-	S	-	-	-	Helix-turn-helix domain
HMCAHBCO_00594	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HMCAHBCO_00595	1.25e-39	-	-	-	M	-	-	-	Lysin motif
HMCAHBCO_00596	1.27e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HMCAHBCO_00597	1.98e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HMCAHBCO_00598	5.89e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HMCAHBCO_00599	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HMCAHBCO_00600	2.08e-284	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HMCAHBCO_00601	1.29e-192	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HMCAHBCO_00602	1.39e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HMCAHBCO_00603	6.04e-290	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HMCAHBCO_00604	6.46e-109	-	-	-	-	-	-	-	-
HMCAHBCO_00605	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HMCAHBCO_00606	6.7e-241	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HMCAHBCO_00607	1.8e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HMCAHBCO_00608	2.03e-189	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HMCAHBCO_00609	1.19e-208	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HMCAHBCO_00610	3.29e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HMCAHBCO_00611	9.33e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HMCAHBCO_00612	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HMCAHBCO_00613	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HMCAHBCO_00614	4.28e-253	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HMCAHBCO_00615	3.53e-160	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HMCAHBCO_00616	1.27e-222	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
HMCAHBCO_00617	1.73e-219	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
HMCAHBCO_00618	5.99e-291	XK27_05470	-	-	E	-	-	-	Methionine synthase
HMCAHBCO_00620	2.25e-207	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HMCAHBCO_00621	8.64e-177	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMCAHBCO_00622	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HMCAHBCO_00623	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HMCAHBCO_00624	1.5e-227	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HMCAHBCO_00625	6.84e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HMCAHBCO_00626	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HMCAHBCO_00627	3.64e-217	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HMCAHBCO_00628	2.4e-137	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HMCAHBCO_00629	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMCAHBCO_00630	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMCAHBCO_00631	2.21e-227	-	-	-	K	-	-	-	Transcriptional regulator
HMCAHBCO_00632	3.21e-215	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HMCAHBCO_00633	3.8e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HMCAHBCO_00634	9.17e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMCAHBCO_00635	1.07e-43	-	-	-	S	-	-	-	YozE SAM-like fold
HMCAHBCO_00636	3.59e-204	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HMCAHBCO_00637	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HMCAHBCO_00638	4.49e-315	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HMCAHBCO_00639	3.22e-87	-	-	-	-	-	-	-	-
HMCAHBCO_00640	0.0	gshR1	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HMCAHBCO_00641	1.48e-98	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HMCAHBCO_00642	4.87e-123	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HMCAHBCO_00643	0.0	tarL	2.7.8.14, 2.7.8.47	-	H	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HMCAHBCO_00644	1.43e-273	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	H	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HMCAHBCO_00645	6.51e-247	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HMCAHBCO_00646	2.13e-151	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HMCAHBCO_00647	4.76e-290	-	-	-	-	-	-	-	-
HMCAHBCO_00648	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HMCAHBCO_00649	7.79e-78	-	-	-	-	-	-	-	-
HMCAHBCO_00650	2.79e-181	-	-	-	-	-	-	-	-
HMCAHBCO_00651	1.06e-312	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HMCAHBCO_00652	1.05e-176	XK27_00890	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
HMCAHBCO_00653	9.3e-167	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
HMCAHBCO_00654	1.33e-67	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
HMCAHBCO_00656	6e-268	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
HMCAHBCO_00657	4.87e-191	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HMCAHBCO_00658	2.37e-65	-	-	-	-	-	-	-	-
HMCAHBCO_00659	1.27e-35	-	-	-	-	-	-	-	-
HMCAHBCO_00660	1.96e-168	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HMCAHBCO_00661	2.47e-101	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
HMCAHBCO_00662	4.53e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
HMCAHBCO_00663	1.97e-87	-	-	-	K	-	-	-	Transcriptional regulator
HMCAHBCO_00664	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HMCAHBCO_00665	1.6e-171	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HMCAHBCO_00666	2.16e-208	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMCAHBCO_00667	1.37e-119	-	-	-	F	-	-	-	NUDIX domain
HMCAHBCO_00668	1.19e-176	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
HMCAHBCO_00669	2.08e-92	-	-	-	S	-	-	-	LuxR family transcriptional regulator
HMCAHBCO_00670	1.92e-168	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
HMCAHBCO_00673	1.9e-93	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HMCAHBCO_00674	3.34e-144	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HMCAHBCO_00675	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HMCAHBCO_00676	4.89e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HMCAHBCO_00677	1.9e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HMCAHBCO_00678	9.72e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HMCAHBCO_00679	1.65e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HMCAHBCO_00680	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HMCAHBCO_00681	5.89e-81	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HMCAHBCO_00682	3.28e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HMCAHBCO_00683	2.44e-267	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
HMCAHBCO_00684	2.13e-186	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
HMCAHBCO_00685	2.27e-247	-	-	-	-	-	-	-	-
HMCAHBCO_00686	1.9e-156	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HMCAHBCO_00687	4.35e-159	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HMCAHBCO_00688	1.38e-232	-	-	-	V	-	-	-	LD-carboxypeptidase
HMCAHBCO_00689	1.23e-311	-	-	-	M	ko:K07273	-	ko00000	hydrolase, family 25
HMCAHBCO_00690	3.2e-70	-	-	-	-	-	-	-	-
HMCAHBCO_00691	3.15e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HMCAHBCO_00692	1.57e-179	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HMCAHBCO_00693	6.42e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HMCAHBCO_00694	9.99e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HMCAHBCO_00695	1.6e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HMCAHBCO_00696	7.69e-300	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HMCAHBCO_00697	1.46e-77	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HMCAHBCO_00698	2.85e-293	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HMCAHBCO_00699	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HMCAHBCO_00700	4.49e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HMCAHBCO_00701	3.33e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMCAHBCO_00702	2.17e-244	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HMCAHBCO_00703	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HMCAHBCO_00704	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HMCAHBCO_00705	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HMCAHBCO_00706	1.61e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HMCAHBCO_00707	1.84e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HMCAHBCO_00708	3.16e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HMCAHBCO_00709	1.21e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HMCAHBCO_00710	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HMCAHBCO_00711	1.62e-173	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HMCAHBCO_00712	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HMCAHBCO_00713	1.01e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HMCAHBCO_00714	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HMCAHBCO_00715	1.28e-276	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HMCAHBCO_00716	3.93e-41	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HMCAHBCO_00717	6.96e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HMCAHBCO_00718	8.28e-73	-	-	-	-	-	-	-	-
HMCAHBCO_00719	1.36e-136	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMCAHBCO_00720	3.8e-224	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HMCAHBCO_00721	7.11e-135	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HMCAHBCO_00722	4.51e-284	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HMCAHBCO_00723	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HMCAHBCO_00724	2.15e-99	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HMCAHBCO_00725	4.49e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HMCAHBCO_00726	7.16e-201	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HMCAHBCO_00727	7.55e-44	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMCAHBCO_00728	3.28e-312	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMCAHBCO_00729	4.82e-194	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HMCAHBCO_00730	2.82e-91	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HMCAHBCO_00731	1.7e-96	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HMCAHBCO_00732	1.43e-129	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HMCAHBCO_00733	4.08e-247	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HMCAHBCO_00734	2.33e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HMCAHBCO_00735	7.97e-71	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HMCAHBCO_00736	1.55e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HMCAHBCO_00737	8.15e-125	-	-	-	K	-	-	-	Transcriptional regulator
HMCAHBCO_00738	9.81e-27	-	-	-	-	-	-	-	-
HMCAHBCO_00741	2.97e-41	-	-	-	-	-	-	-	-
HMCAHBCO_00742	3.11e-73	-	-	-	-	-	-	-	-
HMCAHBCO_00743	2.92e-126	-	-	-	S	-	-	-	Protein conserved in bacteria
HMCAHBCO_00744	1.34e-232	-	-	-	-	-	-	-	-
HMCAHBCO_00745	1.18e-205	-	-	-	-	-	-	-	-
HMCAHBCO_00746	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HMCAHBCO_00747	7.79e-85	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
HMCAHBCO_00748	3.8e-224	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HMCAHBCO_00749	7.77e-179	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HMCAHBCO_00750	1.44e-31	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HMCAHBCO_00751	1.15e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HMCAHBCO_00752	1.62e-141	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HMCAHBCO_00753	2.6e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HMCAHBCO_00754	6.33e-46	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HMCAHBCO_00755	3.52e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HMCAHBCO_00756	9.29e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HMCAHBCO_00757	5.33e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HMCAHBCO_00758	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HMCAHBCO_00759	0.0	-	-	-	S	-	-	-	membrane
HMCAHBCO_00760	6.12e-72	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HMCAHBCO_00761	5.72e-99	-	-	-	K	-	-	-	LytTr DNA-binding domain
HMCAHBCO_00762	9.72e-146	-	-	-	S	-	-	-	membrane
HMCAHBCO_00763	1.09e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMCAHBCO_00764	7.5e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HMCAHBCO_00765	6.11e-249	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HMCAHBCO_00766	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMCAHBCO_00767	6.88e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HMCAHBCO_00768	2.58e-82	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HMCAHBCO_00769	1.72e-120	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HMCAHBCO_00770	4.46e-179	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMCAHBCO_00771	1.37e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HMCAHBCO_00772	6.94e-209	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMCAHBCO_00773	4.18e-121	-	-	-	S	-	-	-	SdpI/YhfL protein family
HMCAHBCO_00774	1.36e-288	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HMCAHBCO_00775	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HMCAHBCO_00776	1.93e-218	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HMCAHBCO_00777	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HMCAHBCO_00778	1.38e-155	csrR	-	-	K	-	-	-	response regulator
HMCAHBCO_00779	2.56e-310	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HMCAHBCO_00780	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HMCAHBCO_00781	1.09e-223	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HMCAHBCO_00782	3.06e-124	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HMCAHBCO_00783	3.66e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HMCAHBCO_00784	3.04e-280	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HMCAHBCO_00785	3.3e-180	yqeM	-	-	Q	-	-	-	Methyltransferase
HMCAHBCO_00786	1.06e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HMCAHBCO_00787	1.71e-149	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HMCAHBCO_00788	4.19e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HMCAHBCO_00789	2.19e-67	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HMCAHBCO_00790	3.81e-276	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HMCAHBCO_00791	5.7e-127	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HMCAHBCO_00792	6.32e-114	-	-	-	-	-	-	-	-
HMCAHBCO_00793	3.97e-174	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HMCAHBCO_00794	1.64e-83	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HMCAHBCO_00795	1.18e-250	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HMCAHBCO_00796	7.03e-307	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
HMCAHBCO_00797	4.59e-73	-	-	-	-	-	-	-	-
HMCAHBCO_00798	6.88e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HMCAHBCO_00799	6.92e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HMCAHBCO_00800	2.37e-109	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HMCAHBCO_00801	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HMCAHBCO_00802	3.5e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HMCAHBCO_00803	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HMCAHBCO_00804	1.58e-117	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HMCAHBCO_00805	1.92e-133	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HMCAHBCO_00806	3.19e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HMCAHBCO_00807	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HMCAHBCO_00808	8.51e-155	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HMCAHBCO_00809	1.04e-141	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HMCAHBCO_00810	4.07e-60	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HMCAHBCO_00811	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HMCAHBCO_00812	2.71e-108	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HMCAHBCO_00813	1.11e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HMCAHBCO_00814	5.21e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HMCAHBCO_00815	1.1e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HMCAHBCO_00816	2.87e-47	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
HMCAHBCO_00817	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HMCAHBCO_00818	3.04e-29	-	-	-	S	-	-	-	Virus attachment protein p12 family
HMCAHBCO_00819	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HMCAHBCO_00820	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HMCAHBCO_00822	1.29e-148	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMCAHBCO_00823	2.94e-71	ytzB	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HMCAHBCO_00824	2.8e-155	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HMCAHBCO_00825	7.24e-197	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
HMCAHBCO_00826	8.17e-285	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HMCAHBCO_00827	1.1e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMCAHBCO_00828	3.6e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HMCAHBCO_00829	6.76e-73	-	-	-	-	-	-	-	-
HMCAHBCO_00830	1.09e-196	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HMCAHBCO_00831	1.78e-153	draG	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HMCAHBCO_00832	5.76e-135	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HMCAHBCO_00833	2.82e-138	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HMCAHBCO_00834	1.94e-247	-	-	-	S	-	-	-	Fn3-like domain
HMCAHBCO_00835	1.65e-80	-	-	-	-	-	-	-	-
HMCAHBCO_00836	0.0	-	-	-	-	-	-	-	-
HMCAHBCO_00837	4.26e-308	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HMCAHBCO_00838	2e-98	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	general stress protein
HMCAHBCO_00839	5.16e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HMCAHBCO_00840	8.38e-152	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HMCAHBCO_00841	2.71e-150	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HMCAHBCO_00842	7.18e-189	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HMCAHBCO_00843	1.96e-116	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HMCAHBCO_00844	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HMCAHBCO_00845	5.77e-151	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HMCAHBCO_00846	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HMCAHBCO_00847	4.7e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMCAHBCO_00848	3.68e-235	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HMCAHBCO_00850	6.46e-113	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
HMCAHBCO_00851	3.03e-27	-	-	-	-	ko:K02671	-	ko00000,ko02035,ko02044	-
HMCAHBCO_00852	1.5e-108	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
HMCAHBCO_00853	1.97e-72	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HMCAHBCO_00854	6.2e-242	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HMCAHBCO_00855	2.57e-224	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HMCAHBCO_00856	2.06e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HMCAHBCO_00857	2.21e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HMCAHBCO_00858	2.44e-65	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
HMCAHBCO_00859	3.21e-210	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HMCAHBCO_00860	5.44e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HMCAHBCO_00861	7.36e-274	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HMCAHBCO_00862	9.86e-82	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HMCAHBCO_00863	1.6e-96	-	-	-	-	-	-	-	-
HMCAHBCO_00864	1.88e-75	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HMCAHBCO_00865	2.31e-202	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HMCAHBCO_00866	6.72e-289	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HMCAHBCO_00867	2.29e-112	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HMCAHBCO_00868	7.94e-114	ykuL	-	-	S	-	-	-	(CBS) domain
HMCAHBCO_00869	4.03e-125	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HMCAHBCO_00870	8.49e-144	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HMCAHBCO_00871	5.06e-194	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HMCAHBCO_00872	1.45e-161	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HMCAHBCO_00873	3e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HMCAHBCO_00874	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HMCAHBCO_00875	1.06e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HMCAHBCO_00876	1.31e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HMCAHBCO_00877	5.39e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HMCAHBCO_00878	5e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HMCAHBCO_00879	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HMCAHBCO_00880	2.79e-316	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HMCAHBCO_00881	8.32e-227	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HMCAHBCO_00882	2.48e-276	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMCAHBCO_00883	1.32e-63	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HMCAHBCO_00884	9.91e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HMCAHBCO_00885	5.87e-256	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HMCAHBCO_00886	2.62e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HMCAHBCO_00887	2.83e-138	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HMCAHBCO_00888	4.02e-114	-	-	-	-	-	-	-	-
HMCAHBCO_00889	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HMCAHBCO_00890	1.3e-91	-	-	-	-	-	-	-	-
HMCAHBCO_00891	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
HMCAHBCO_00892	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HMCAHBCO_00893	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HMCAHBCO_00894	6.18e-197	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
HMCAHBCO_00895	6.57e-291	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HMCAHBCO_00896	2.43e-264	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HMCAHBCO_00897	3.83e-295	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HMCAHBCO_00898	1.92e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HMCAHBCO_00899	5.74e-172	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HMCAHBCO_00900	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
HMCAHBCO_00901	3.55e-296	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HMCAHBCO_00902	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HMCAHBCO_00903	2.61e-199	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HMCAHBCO_00904	3.17e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HMCAHBCO_00905	1.89e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HMCAHBCO_00906	1.23e-187	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HMCAHBCO_00907	3.81e-150	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HMCAHBCO_00908	9.47e-115	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HMCAHBCO_00909	3.76e-184	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HMCAHBCO_00910	1.74e-211	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HMCAHBCO_00911	1.15e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HMCAHBCO_00912	5.62e-316	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HMCAHBCO_00913	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HMCAHBCO_00914	3.56e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HMCAHBCO_00915	1.57e-299	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
HMCAHBCO_00916	8.93e-291	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HMCAHBCO_00917	2.59e-277	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HMCAHBCO_00919	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HMCAHBCO_00920	7.5e-105	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HMCAHBCO_00921	2.15e-137	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HMCAHBCO_00922	4.02e-145	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HMCAHBCO_00923	1.63e-104	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HMCAHBCO_00924	1.24e-139	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HMCAHBCO_00925	9.17e-59	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HMCAHBCO_00926	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HMCAHBCO_00927	7.27e-303	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HMCAHBCO_00928	1.34e-52	-	-	-	-	-	-	-	-
HMCAHBCO_00929	2.37e-107	uspA	-	-	T	-	-	-	universal stress protein
HMCAHBCO_00930	1.1e-258	bla2	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HMCAHBCO_00931	4.7e-207	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HMCAHBCO_00932	0.0	glpQ3	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HMCAHBCO_00933	6.54e-273	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HMCAHBCO_00934	7.55e-242	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HMCAHBCO_00935	3.26e-227	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HMCAHBCO_00936	3.34e-215	hicD3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HMCAHBCO_00937	8.69e-191	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HMCAHBCO_00938	2.1e-151	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HMCAHBCO_00939	2.24e-239	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HMCAHBCO_00940	3.2e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
HMCAHBCO_00941	2.15e-280	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HMCAHBCO_00942	1.04e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HMCAHBCO_00943	1.52e-57	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HMCAHBCO_00944	1.44e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HMCAHBCO_00945	1.68e-132	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HMCAHBCO_00946	4.85e-314	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMCAHBCO_00947	5.95e-74	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HMCAHBCO_00948	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HMCAHBCO_00949	9.14e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HMCAHBCO_00950	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HMCAHBCO_00951	2.03e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMCAHBCO_00952	5.41e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HMCAHBCO_00953	1.81e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMCAHBCO_00954	4.82e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HMCAHBCO_00955	1.01e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HMCAHBCO_00956	7.21e-145	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
HMCAHBCO_00957	2.31e-132	thgA3	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HMCAHBCO_00958	2.49e-167	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HMCAHBCO_00959	8.81e-205	-	-	-	S	-	-	-	Alpha beta hydrolase
HMCAHBCO_00960	1.39e-143	-	-	-	GM	-	-	-	NmrA-like family
HMCAHBCO_00961	1.74e-101	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
HMCAHBCO_00962	5.72e-207	-	-	-	K	-	-	-	Transcriptional regulator
HMCAHBCO_00963	3.78e-221	cryZ	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HMCAHBCO_00965	0.0	nox4	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HMCAHBCO_00966	1.51e-132	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
HMCAHBCO_00967	5.11e-266	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HMCAHBCO_00968	1.27e-174	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HMCAHBCO_00969	4.17e-204	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HMCAHBCO_00971	6.64e-109	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HMCAHBCO_00972	2.25e-93	-	-	-	K	-	-	-	MarR family
HMCAHBCO_00973	1.49e-147	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMCAHBCO_00974	0.000138	yjdF	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HMCAHBCO_00975	1.03e-206	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMCAHBCO_00976	6.05e-170	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HMCAHBCO_00977	1.43e-251	-	-	-	-	-	-	-	-
HMCAHBCO_00978	5.23e-256	-	-	-	-	-	-	-	-
HMCAHBCO_00979	4.94e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMCAHBCO_00980	1.18e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HMCAHBCO_00981	1.74e-251	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HMCAHBCO_00982	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HMCAHBCO_00983	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HMCAHBCO_00984	8.64e-224	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HMCAHBCO_00985	2.84e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HMCAHBCO_00986	7.92e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HMCAHBCO_00987	1.15e-94	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HMCAHBCO_00988	3.14e-109	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HMCAHBCO_00989	4.81e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HMCAHBCO_00990	9.21e-94	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HMCAHBCO_00991	1.09e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HMCAHBCO_00992	2.32e-194	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HMCAHBCO_00993	1.78e-140	-	-	-	C	-	-	-	Enoyl-(Acyl carrier protein) reductase
HMCAHBCO_00994	1.42e-217	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HMCAHBCO_00995	1.84e-284	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HMCAHBCO_00996	4.35e-204	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMCAHBCO_00997	2.61e-132	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMCAHBCO_00998	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HMCAHBCO_00999	2.47e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HMCAHBCO_01000	4.01e-200	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
HMCAHBCO_01001	2.29e-207	-	-	-	G	-	-	-	Fructosamine kinase
HMCAHBCO_01002	2.43e-150	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
HMCAHBCO_01003	8.2e-102	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HMCAHBCO_01004	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HMCAHBCO_01005	2.56e-76	-	-	-	-	-	-	-	-
HMCAHBCO_01006	3.13e-172	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HMCAHBCO_01007	2.04e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HMCAHBCO_01008	5.28e-146	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HMCAHBCO_01009	4.78e-65	-	-	-	-	-	-	-	-
HMCAHBCO_01010	1.73e-67	-	-	-	-	-	-	-	-
HMCAHBCO_01013	1.01e-158	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HMCAHBCO_01014	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HMCAHBCO_01015	1.68e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HMCAHBCO_01016	5.75e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMCAHBCO_01017	3.27e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HMCAHBCO_01018	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMCAHBCO_01019	8.59e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HMCAHBCO_01020	8.49e-266	pbpX2	-	-	V	-	-	-	Beta-lactamase
HMCAHBCO_01021	2.54e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HMCAHBCO_01022	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HMCAHBCO_01023	4.52e-111	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HMCAHBCO_01024	4.42e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HMCAHBCO_01025	1.19e-169	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HMCAHBCO_01026	2.53e-240	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HMCAHBCO_01027	8.94e-221	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HMCAHBCO_01028	2.41e-113	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HMCAHBCO_01029	1.21e-245	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HMCAHBCO_01030	1.19e-285	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HMCAHBCO_01031	1.63e-121	-	-	-	-	-	-	-	-
HMCAHBCO_01032	3.67e-275	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HMCAHBCO_01033	0.0	-	-	-	G	-	-	-	Major Facilitator
HMCAHBCO_01034	3.04e-71	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HMCAHBCO_01035	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HMCAHBCO_01036	3.28e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
HMCAHBCO_01037	2.95e-65	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HMCAHBCO_01038	4.46e-275	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HMCAHBCO_01039	9.74e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HMCAHBCO_01040	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMCAHBCO_01041	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HMCAHBCO_01042	4.64e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HMCAHBCO_01043	1.13e-175	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HMCAHBCO_01044	3.17e-190	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HMCAHBCO_01045	9.83e-113	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HMCAHBCO_01046	3.01e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HMCAHBCO_01047	1.88e-194	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HMCAHBCO_01048	6.33e-185	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HMCAHBCO_01049	2.92e-172	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
HMCAHBCO_01050	1.92e-239	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMCAHBCO_01051	5.67e-64	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HMCAHBCO_01052	2.11e-171	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HMCAHBCO_01053	8.8e-155	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HMCAHBCO_01054	3.96e-44	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HMCAHBCO_01055	7.68e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
HMCAHBCO_01056	7.22e-149	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HMCAHBCO_01057	7.8e-123	-	-	-	-	-	-	-	-
HMCAHBCO_01058	1.56e-276	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HMCAHBCO_01059	1.38e-98	-	-	-	-	-	-	-	-
HMCAHBCO_01060	3.81e-87	-	-	-	-	-	-	-	-
HMCAHBCO_01061	1.14e-226	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family 2
HMCAHBCO_01062	2.19e-131	-	-	-	L	-	-	-	Helix-turn-helix domain
HMCAHBCO_01063	4.46e-281	ywtF_2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HMCAHBCO_01064	3.82e-184	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HMCAHBCO_01065	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMCAHBCO_01066	1.96e-293	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Cell cycle protein
HMCAHBCO_01068	8.59e-85	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HMCAHBCO_01069	1.13e-182	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HMCAHBCO_01070	3.66e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HMCAHBCO_01071	3.3e-202	degV1	-	-	S	-	-	-	DegV family
HMCAHBCO_01072	2.89e-80	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
HMCAHBCO_01073	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HMCAHBCO_01075	2.76e-141	sip3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HMCAHBCO_01076	0.0	-	-	-	-	-	-	-	-
HMCAHBCO_01078	2.13e-209	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HMCAHBCO_01079	2.16e-142	-	-	-	S	-	-	-	Cell surface protein
HMCAHBCO_01080	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HMCAHBCO_01081	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HMCAHBCO_01082	2.14e-155	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HMCAHBCO_01083	3.75e-305	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
HMCAHBCO_01084	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HMCAHBCO_01085	1.55e-158	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMCAHBCO_01086	3.74e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HMCAHBCO_01087	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HMCAHBCO_01088	8.19e-267	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HMCAHBCO_01089	3.82e-51	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HMCAHBCO_01090	7.24e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HMCAHBCO_01091	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMCAHBCO_01092	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMCAHBCO_01093	5.95e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HMCAHBCO_01094	1.59e-95	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HMCAHBCO_01095	2.69e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HMCAHBCO_01096	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HMCAHBCO_01097	3.44e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HMCAHBCO_01098	8.77e-317	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HMCAHBCO_01099	4.96e-289	yttB	-	-	EGP	-	-	-	Major Facilitator
HMCAHBCO_01100	9e-184	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HMCAHBCO_01101	2.19e-290	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HMCAHBCO_01103	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HMCAHBCO_01104	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HMCAHBCO_01105	6.65e-282	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HMCAHBCO_01106	3.49e-269	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HMCAHBCO_01107	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HMCAHBCO_01108	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HMCAHBCO_01109	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HMCAHBCO_01110	8.38e-184	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HMCAHBCO_01111	1.1e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HMCAHBCO_01112	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
HMCAHBCO_01113	3.21e-104	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
HMCAHBCO_01114	4.37e-43	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein domain
HMCAHBCO_01115	2.54e-50	-	-	-	-	-	-	-	-
HMCAHBCO_01117	2.22e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HMCAHBCO_01118	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HMCAHBCO_01119	3.55e-313	yycH	-	-	S	-	-	-	YycH protein
HMCAHBCO_01120	3.54e-195	yycI	-	-	S	-	-	-	YycH protein
HMCAHBCO_01121	1.71e-200	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HMCAHBCO_01122	1.5e-253	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HMCAHBCO_01123	6.08e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HMCAHBCO_01124	3.46e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMCAHBCO_01125	0.0	-	-	-	C	-	-	-	Belongs to the aldehyde dehydrogenase family
HMCAHBCO_01126	6.96e-214	-	-	-	L	-	-	-	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HMCAHBCO_01127	5.97e-157	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HMCAHBCO_01128	4.75e-42	pnb	-	-	C	-	-	-	nitroreductase
HMCAHBCO_01129	5.63e-86	pnb	-	-	C	-	-	-	nitroreductase
HMCAHBCO_01130	4.95e-86	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
HMCAHBCO_01131	1.57e-150	-	-	-	S	-	-	-	Elongation factor G-binding protein, N-terminal
HMCAHBCO_01132	0.0	-	-	-	C	-	-	-	FMN_bind
HMCAHBCO_01133	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HMCAHBCO_01134	1.46e-204	-	-	-	K	-	-	-	LysR family
HMCAHBCO_01135	2.49e-95	-	-	-	C	-	-	-	FMN binding
HMCAHBCO_01136	4.48e-98	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HMCAHBCO_01137	4.06e-211	-	-	-	S	-	-	-	KR domain
HMCAHBCO_01138	5.74e-204	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
HMCAHBCO_01139	5.07e-157	ydgI	-	-	C	-	-	-	Nitroreductase family
HMCAHBCO_01140	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HMCAHBCO_01141	1.56e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HMCAHBCO_01142	7.63e-249	pva1	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HMCAHBCO_01143	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HMCAHBCO_01144	6.86e-175	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HMCAHBCO_01145	0.0	hpaH	1.14.14.8, 1.14.14.9	-	Q	ko:K00483,ko:K16901	ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220	ko00000,ko00001,ko01000	4-hydroxyphenylacetate
HMCAHBCO_01146	1.65e-106	-	-	-	S	-	-	-	ASCH
HMCAHBCO_01147	1.25e-164	-	-	-	F	-	-	-	glutamine amidotransferase
HMCAHBCO_01148	1.67e-220	-	-	-	K	-	-	-	WYL domain
HMCAHBCO_01149	1.63e-152	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HMCAHBCO_01150	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HMCAHBCO_01151	7.44e-51	-	-	-	S	-	-	-	Protein of unknown function
HMCAHBCO_01152	2.7e-79	-	-	-	S	-	-	-	Protein of unknown function
HMCAHBCO_01153	8.64e-195	-	-	-	EG	-	-	-	EamA-like transporter family
HMCAHBCO_01154	7.65e-121	yfbM	-	-	K	-	-	-	FR47-like protein
HMCAHBCO_01155	1.4e-162	-	-	-	S	-	-	-	DJ-1/PfpI family
HMCAHBCO_01156	3.14e-230	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HMCAHBCO_01157	1.92e-67	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HMCAHBCO_01158	5.98e-302	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HMCAHBCO_01159	2.81e-194	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HMCAHBCO_01160	9.06e-112	-	-	-	-	-	-	-	-
HMCAHBCO_01161	2.05e-179	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HMCAHBCO_01162	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HMCAHBCO_01164	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
HMCAHBCO_01165	8.08e-135	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
HMCAHBCO_01166	6.03e-226	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HMCAHBCO_01167	2.41e-165	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HMCAHBCO_01168	1.57e-142	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HMCAHBCO_01169	5.13e-287	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HMCAHBCO_01170	4.82e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HMCAHBCO_01171	5.89e-126	entB	-	-	Q	-	-	-	Isochorismatase family
HMCAHBCO_01172	1.36e-210	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
HMCAHBCO_01173	1.95e-88	ybbJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HMCAHBCO_01174	1.62e-276	-	-	-	E	-	-	-	glutamate:sodium symporter activity
HMCAHBCO_01175	3.38e-274	hipO1	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	Peptidase family M20/M25/M40
HMCAHBCO_01176	2.69e-252	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HMCAHBCO_01177	1.49e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HMCAHBCO_01179	6.84e-186	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HMCAHBCO_01180	1.62e-229	yneE	-	-	K	-	-	-	Transcriptional regulator
HMCAHBCO_01181	8.55e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HMCAHBCO_01182	1.62e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HMCAHBCO_01183	6.16e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMCAHBCO_01184	3.47e-215	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HMCAHBCO_01185	1.26e-162	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HMCAHBCO_01186	1.8e-288	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HMCAHBCO_01187	2.14e-95	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HMCAHBCO_01188	1.71e-91	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HMCAHBCO_01189	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HMCAHBCO_01190	6.43e-203	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HMCAHBCO_01191	4.82e-179	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HMCAHBCO_01192	2.29e-175	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HMCAHBCO_01193	5.01e-129	-	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
HMCAHBCO_01194	1.48e-161	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HMCAHBCO_01195	7.52e-207	-	-	-	K	-	-	-	LysR substrate binding domain
HMCAHBCO_01196	2.01e-113	ykhA	-	-	I	-	-	-	Thioesterase superfamily
HMCAHBCO_01197	4.4e-246	rsgA_2	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HMCAHBCO_01198	4.09e-119	-	-	-	K	-	-	-	transcriptional regulator
HMCAHBCO_01199	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HMCAHBCO_01200	1.14e-193	-	-	-	O	-	-	-	Band 7 protein
HMCAHBCO_01201	1.48e-71	-	-	-	-	-	-	-	-
HMCAHBCO_01202	2.02e-39	-	-	-	-	-	-	-	-
HMCAHBCO_01203	6.57e-274	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HMCAHBCO_01204	3.2e-37	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HMCAHBCO_01205	9.96e-147	-	1.14.99.53	AA10	S	ko:K21713	-	ko00000,ko01000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
HMCAHBCO_01206	5.93e-60	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HMCAHBCO_01207	2.05e-55	-	-	-	-	-	-	-	-
HMCAHBCO_01208	6.05e-108	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
HMCAHBCO_01209	5.28e-100	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HMCAHBCO_01210	5.58e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HMCAHBCO_01211	1.21e-209	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HMCAHBCO_01212	8.76e-48	-	-	-	-	-	-	-	-
HMCAHBCO_01213	5.79e-21	-	-	-	-	-	-	-	-
HMCAHBCO_01214	2.22e-55	-	-	-	S	-	-	-	transglycosylase associated protein
HMCAHBCO_01215	4e-40	-	-	-	S	-	-	-	CsbD-like
HMCAHBCO_01216	1.06e-53	-	-	-	-	-	-	-	-
HMCAHBCO_01217	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HMCAHBCO_01218	8.39e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HMCAHBCO_01219	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HMCAHBCO_01220	1.48e-218	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HMCAHBCO_01221	5.03e-182	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
HMCAHBCO_01222	1.25e-66	-	-	-	-	-	-	-	-
HMCAHBCO_01223	3.23e-58	-	-	-	-	-	-	-	-
HMCAHBCO_01224	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HMCAHBCO_01225	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HMCAHBCO_01226	3.86e-192	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HMCAHBCO_01227	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HMCAHBCO_01228	3.24e-155	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HMCAHBCO_01229	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HMCAHBCO_01230	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HMCAHBCO_01231	3.36e-247	galM2	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HMCAHBCO_01232	8.61e-251	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HMCAHBCO_01233	2.94e-261	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HMCAHBCO_01234	1.1e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HMCAHBCO_01235	1.48e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HMCAHBCO_01236	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HMCAHBCO_01237	2.53e-107	ypmB	-	-	S	-	-	-	protein conserved in bacteria
HMCAHBCO_01238	3.1e-289	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HMCAHBCO_01239	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HMCAHBCO_01240	9.32e-165	dnaD	-	-	L	ko:K02086	-	ko00000	Replication initiation and membrane attachment
HMCAHBCO_01242	2.32e-238	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HMCAHBCO_01243	2.45e-142	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HMCAHBCO_01244	1.58e-203	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HMCAHBCO_01245	5.32e-109	-	-	-	T	-	-	-	Universal stress protein family
HMCAHBCO_01246	0.0	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMCAHBCO_01247	8.06e-234	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HMCAHBCO_01248	4.64e-228	phnT	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HMCAHBCO_01249	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HMCAHBCO_01250	3.6e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HMCAHBCO_01251	2.12e-142	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HMCAHBCO_01252	9.98e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HMCAHBCO_01254	1.44e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HMCAHBCO_01255	1.26e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HMCAHBCO_01256	1.55e-309	-	-	-	P	-	-	-	Major Facilitator Superfamily
HMCAHBCO_01257	4.17e-186	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HMCAHBCO_01258	9.19e-95	-	-	-	S	-	-	-	SnoaL-like domain
HMCAHBCO_01259	9.63e-307	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HMCAHBCO_01260	3.46e-267	mccF	-	-	V	-	-	-	LD-carboxypeptidase
HMCAHBCO_01261	1.66e-101	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HMCAHBCO_01262	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HMCAHBCO_01263	1.56e-46	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HMCAHBCO_01264	3.91e-289	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HMCAHBCO_01265	2.29e-292	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HMCAHBCO_01266	2.16e-241	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HMCAHBCO_01267	2.04e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HMCAHBCO_01268	1.41e-285	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HMCAHBCO_01269	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HMCAHBCO_01270	1.24e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HMCAHBCO_01271	5.6e-41	-	-	-	-	-	-	-	-
HMCAHBCO_01272	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HMCAHBCO_01273	3.29e-95	-	-	-	L	-	-	-	Integrase
HMCAHBCO_01274	3.4e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HMCAHBCO_01275	5.67e-231	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HMCAHBCO_01276	4.86e-258	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HMCAHBCO_01277	3.59e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMCAHBCO_01278	3.44e-210	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMCAHBCO_01279	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HMCAHBCO_01280	3.85e-76	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
HMCAHBCO_01281	1.01e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HMCAHBCO_01282	1.36e-208	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HMCAHBCO_01283	1.01e-250	-	-	-	M	-	-	-	MucBP domain
HMCAHBCO_01284	0.0	-	-	-	-	-	-	-	-
HMCAHBCO_01285	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HMCAHBCO_01286	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HMCAHBCO_01287	1.22e-218	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HMCAHBCO_01288	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HMCAHBCO_01289	7.89e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HMCAHBCO_01290	6.04e-94	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HMCAHBCO_01291	1.13e-257	yueF	-	-	S	-	-	-	AI-2E family transporter
HMCAHBCO_01292	7.3e-216	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HMCAHBCO_01293	7.17e-39	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HMCAHBCO_01294	3.97e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
HMCAHBCO_01295	1.94e-170	lytE	-	-	M	-	-	-	NlpC/P60 family
HMCAHBCO_01296	6.62e-138	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HMCAHBCO_01297	1.01e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HMCAHBCO_01298	1.34e-168	-	-	-	-	-	-	-	-
HMCAHBCO_01299	1.68e-131	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HMCAHBCO_01300	3.31e-35	-	-	-	-	-	-	-	-
HMCAHBCO_01301	1.95e-41	-	-	-	-	-	-	-	-
HMCAHBCO_01302	1.04e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HMCAHBCO_01303	9.02e-70	-	-	-	-	-	-	-	-
HMCAHBCO_01305	3.98e-169	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HMCAHBCO_01306	1.95e-197	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HMCAHBCO_01307	3.34e-267	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HMCAHBCO_01308	3.3e-281	pbpX	-	-	V	-	-	-	Beta-lactamase
HMCAHBCO_01309	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HMCAHBCO_01310	8.31e-139	-	-	-	-	-	-	-	-
HMCAHBCO_01311	7.62e-97	-	-	-	-	-	-	-	-
HMCAHBCO_01313	3.21e-209	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HMCAHBCO_01314	3.15e-313	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMCAHBCO_01315	3.93e-99	-	-	-	T	-	-	-	Universal stress protein family
HMCAHBCO_01317	5.62e-316	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HMCAHBCO_01318	7.89e-245	mocA	-	-	S	-	-	-	Oxidoreductase
HMCAHBCO_01319	6.22e-43	cspP	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HMCAHBCO_01320	7.34e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HMCAHBCO_01321	2.22e-185	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HMCAHBCO_01322	5.63e-196	gntR	-	-	K	-	-	-	rpiR family
HMCAHBCO_01323	2.87e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HMCAHBCO_01324	7.06e-307	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMCAHBCO_01325	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HMCAHBCO_01326	2.26e-129	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMCAHBCO_01327	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMCAHBCO_01328	1.59e-242	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HMCAHBCO_01329	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMCAHBCO_01330	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HMCAHBCO_01331	5.11e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMCAHBCO_01332	9.48e-263	camS	-	-	S	-	-	-	sex pheromone
HMCAHBCO_01333	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HMCAHBCO_01334	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HMCAHBCO_01335	1.39e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HMCAHBCO_01336	1.13e-120	yebE	-	-	S	-	-	-	UPF0316 protein
HMCAHBCO_01337	2.01e-134	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HMCAHBCO_01338	1.97e-145	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HMCAHBCO_01339	7.78e-235	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HMCAHBCO_01340	1.37e-83	-	-	-	K	-	-	-	Helix-turn-helix domain
HMCAHBCO_01341	1.08e-71	-	-	-	-	-	-	-	-
HMCAHBCO_01342	1.66e-96	-	-	-	-	-	-	-	-
HMCAHBCO_01343	6.67e-30	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HMCAHBCO_01344	8.56e-38	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HMCAHBCO_01345	9.16e-61	-	-	-	L	-	-	-	Helix-turn-helix domain
HMCAHBCO_01347	3.56e-171	spoVK	-	-	O	ko:K06413	-	ko00000	ATPase family associated with various cellular activities (AAA)
HMCAHBCO_01349	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HMCAHBCO_01350	1.22e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HMCAHBCO_01351	8.45e-211	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
HMCAHBCO_01352	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HMCAHBCO_01353	4.51e-143	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HMCAHBCO_01354	4.16e-227	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HMCAHBCO_01355	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HMCAHBCO_01356	2.07e-161	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
HMCAHBCO_01357	1.35e-165	pgm3	-	-	G	-	-	-	Phosphoglycerate mutase family
HMCAHBCO_01358	1.61e-36	-	-	-	-	-	-	-	-
HMCAHBCO_01359	3.5e-64	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
HMCAHBCO_01360	4.6e-102	rppH3	-	-	F	-	-	-	NUDIX domain
HMCAHBCO_01361	5.95e-300	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HMCAHBCO_01362	1.81e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMCAHBCO_01363	2.93e-109	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HMCAHBCO_01364	3.22e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HMCAHBCO_01365	7.26e-92	-	-	-	K	-	-	-	MarR family
HMCAHBCO_01366	8.87e-191	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
HMCAHBCO_01367	6.26e-96	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HMCAHBCO_01368	9.38e-317	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HMCAHBCO_01369	4.87e-180	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
HMCAHBCO_01370	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HMCAHBCO_01371	7.77e-197	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HMCAHBCO_01372	7.04e-108	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HMCAHBCO_01373	1.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HMCAHBCO_01374	3.14e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HMCAHBCO_01375	3.39e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HMCAHBCO_01376	2.3e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HMCAHBCO_01378	1.28e-54	-	-	-	-	-	-	-	-
HMCAHBCO_01379	2.07e-217	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMCAHBCO_01380	1.05e-234	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HMCAHBCO_01381	1.94e-95	gph1	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant
HMCAHBCO_01382	1.01e-188	-	-	-	-	-	-	-	-
HMCAHBCO_01383	8.84e-18	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HMCAHBCO_01384	2.02e-106	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HMCAHBCO_01385	2.45e-134	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HMCAHBCO_01386	1.48e-27	-	-	-	-	-	-	-	-
HMCAHBCO_01387	7.48e-96	-	-	-	F	-	-	-	Nudix hydrolase
HMCAHBCO_01388	1.23e-189	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HMCAHBCO_01389	6.12e-115	-	-	-	-	-	-	-	-
HMCAHBCO_01390	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HMCAHBCO_01391	3.8e-61	-	-	-	-	-	-	-	-
HMCAHBCO_01392	1.55e-89	-	-	-	O	-	-	-	OsmC-like protein
HMCAHBCO_01393	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HMCAHBCO_01394	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HMCAHBCO_01395	5.01e-229	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HMCAHBCO_01396	3.45e-231	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HMCAHBCO_01397	0.0	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HMCAHBCO_01398	5.47e-198	ribC1	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HMCAHBCO_01399	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HMCAHBCO_01400	1.79e-287	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HMCAHBCO_01401	1.36e-27	-	-	-	-	-	-	-	-
HMCAHBCO_01402	3.68e-107	-	-	-	K	-	-	-	Transcriptional regulator
HMCAHBCO_01403	7.8e-196	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HMCAHBCO_01404	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HMCAHBCO_01405	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HMCAHBCO_01406	4.45e-226	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HMCAHBCO_01407	3.49e-315	-	-	-	EGP	-	-	-	Major Facilitator
HMCAHBCO_01408	1.71e-116	-	-	-	V	-	-	-	VanZ like family
HMCAHBCO_01409	3.88e-46	-	-	-	-	-	-	-	-
HMCAHBCO_01410	5.45e-94	spx1	-	-	P	ko:K16509	-	ko00000	ArsC family
HMCAHBCO_01412	6.37e-186	-	-	-	-	-	-	-	-
HMCAHBCO_01413	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HMCAHBCO_01414	7.08e-197	-	-	-	G	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HMCAHBCO_01415	2.87e-168	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HMCAHBCO_01416	2.49e-95	-	-	-	-	-	-	-	-
HMCAHBCO_01417	3.38e-70	-	-	-	-	-	-	-	-
HMCAHBCO_01418	1.46e-263	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HMCAHBCO_01419	1.21e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMCAHBCO_01420	8.04e-190	-	3.1.3.23	-	S	ko:K07757	-	ko00000,ko01000	Sucrose-6F-phosphate phosphohydrolase
HMCAHBCO_01421	5.44e-159	-	-	-	T	-	-	-	EAL domain
HMCAHBCO_01432	3.26e-119	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
HMCAHBCO_01433	6.36e-237	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
HMCAHBCO_01434	1.25e-124	-	-	-	-	-	-	-	-
HMCAHBCO_01435	1.58e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HMCAHBCO_01436	2.98e-46	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HMCAHBCO_01437	3.47e-134	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HMCAHBCO_01439	2.19e-291	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HMCAHBCO_01440	6.21e-241	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HMCAHBCO_01441	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HMCAHBCO_01442	2.75e-216	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HMCAHBCO_01443	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HMCAHBCO_01444	3.35e-157	-	-	-	-	-	-	-	-
HMCAHBCO_01445	2.78e-273	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HMCAHBCO_01446	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
HMCAHBCO_01447	1.37e-60	-	-	-	N	-	-	-	Cell shape-determining protein MreB
HMCAHBCO_01448	1.21e-185	-	-	-	N	-	-	-	Cell shape-determining protein MreB
HMCAHBCO_01449	0.0	-	-	-	S	-	-	-	Pfam Methyltransferase
HMCAHBCO_01450	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HMCAHBCO_01451	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HMCAHBCO_01452	9.32e-40	-	-	-	-	-	-	-	-
HMCAHBCO_01453	3.03e-122	mraW1	-	-	J	-	-	-	Putative rRNA methylase
HMCAHBCO_01454	3.58e-161	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HMCAHBCO_01455	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HMCAHBCO_01456	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HMCAHBCO_01457	5.04e-176	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HMCAHBCO_01458	3.03e-193	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HMCAHBCO_01459	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HMCAHBCO_01460	2.16e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HMCAHBCO_01461	2.92e-258	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
HMCAHBCO_01462	1.13e-221	ugpA	-	-	U	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMCAHBCO_01463	3.05e-193	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HMCAHBCO_01464	5.01e-229	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HMCAHBCO_01465	2.07e-155	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HMCAHBCO_01466	3.55e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HMCAHBCO_01467	3e-315	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
HMCAHBCO_01469	3.34e-160	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HMCAHBCO_01470	3.06e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HMCAHBCO_01471	2.57e-226	-	-	-	K	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
HMCAHBCO_01473	6.96e-198	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMCAHBCO_01474	5.2e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HMCAHBCO_01475	1.64e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
HMCAHBCO_01476	9.36e-205	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HMCAHBCO_01477	1.89e-189	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HMCAHBCO_01478	7.83e-140	-	-	-	-	-	-	-	-
HMCAHBCO_01479	2.08e-283	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HMCAHBCO_01480	9.01e-179	agrA	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HMCAHBCO_01481	5.37e-74	-	-	-	-	-	-	-	-
HMCAHBCO_01482	4.56e-78	-	-	-	-	-	-	-	-
HMCAHBCO_01483	1.23e-145	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HMCAHBCO_01484	2.2e-111	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HMCAHBCO_01485	8.82e-119	-	-	-	-	-	-	-	-
HMCAHBCO_01486	7.12e-62	-	-	-	-	-	-	-	-
HMCAHBCO_01487	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
HMCAHBCO_01490	4.29e-87	-	-	-	-	-	-	-	-
HMCAHBCO_01491	9.03e-16	-	-	-	-	-	-	-	-
HMCAHBCO_01492	3.89e-237	-	-	-	-	-	-	-	-
HMCAHBCO_01493	4.91e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
HMCAHBCO_01494	8.01e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
HMCAHBCO_01495	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HMCAHBCO_01496	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HMCAHBCO_01497	0.0	-	-	-	S	-	-	-	Protein conserved in bacteria
HMCAHBCO_01498	7.32e-292	sat	2.7.7.4	-	H	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HMCAHBCO_01499	3.72e-145	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HMCAHBCO_01500	2.54e-225	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
HMCAHBCO_01501	0.0	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
HMCAHBCO_01502	0.0	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HMCAHBCO_01503	4.75e-157	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HMCAHBCO_01504	1.13e-171	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HMCAHBCO_01505	4.87e-156	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HMCAHBCO_01506	4.32e-294	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HMCAHBCO_01507	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HMCAHBCO_01508	1.96e-137	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HMCAHBCO_01509	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HMCAHBCO_01510	1.17e-135	-	-	-	K	-	-	-	transcriptional regulator
HMCAHBCO_01511	2.04e-158	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HMCAHBCO_01512	1.49e-63	-	-	-	-	-	-	-	-
HMCAHBCO_01513	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HMCAHBCO_01514	5.06e-236	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HMCAHBCO_01515	2.87e-56	-	-	-	-	-	-	-	-
HMCAHBCO_01516	1.6e-73	-	-	-	-	-	-	-	-
HMCAHBCO_01517	6.86e-311	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMCAHBCO_01518	2.78e-167	yidA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HMCAHBCO_01519	9.86e-65	-	-	-	-	-	-	-	-
HMCAHBCO_01520	2.58e-163	rrp2	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HMCAHBCO_01521	1.72e-315	hpk2	-	-	T	-	-	-	Histidine kinase
HMCAHBCO_01522	2.2e-86	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HMCAHBCO_01523	0.0	ydiC	-	-	EGP	-	-	-	Major Facilitator
HMCAHBCO_01524	3.13e-55	-	-	-	-	-	-	-	-
HMCAHBCO_01525	6.37e-52	-	-	-	-	-	-	-	-
HMCAHBCO_01526	4.5e-150	-	-	-	-	-	-	-	-
HMCAHBCO_01527	4.02e-301	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HMCAHBCO_01528	8.62e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMCAHBCO_01529	8.9e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
HMCAHBCO_01530	2.73e-92	-	-	-	-	-	-	-	-
HMCAHBCO_01531	3.37e-129	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HMCAHBCO_01532	0.0	tagF2	2.7.8.12	-	H	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HMCAHBCO_01533	5.71e-306	tagB	2.7.8.12, 2.7.8.45	-	M	ko:K09809,ko:K21591	-	ko00000,ko01000	glycerophosphotransferase
HMCAHBCO_01534	1.21e-94	tagD	2.7.7.15, 2.7.7.39	-	IM	ko:K00968,ko:K00980	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Glycerol-3-phosphate cytidylyltransferase
HMCAHBCO_01535	2.6e-185	-	-	-	-	-	-	-	-
HMCAHBCO_01536	0.0	pts5ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HMCAHBCO_01537	0.0	pts4ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HMCAHBCO_01538	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HMCAHBCO_01539	1.68e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HMCAHBCO_01540	6.35e-56	-	-	-	-	-	-	-	-
HMCAHBCO_01541	7.55e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
HMCAHBCO_01542	1.27e-181	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HMCAHBCO_01543	6.72e-203	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HMCAHBCO_01544	2.52e-209	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HMCAHBCO_01545	7.87e-266	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HMCAHBCO_01546	2.13e-124	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
HMCAHBCO_01547	1.82e-126	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
HMCAHBCO_01548	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HMCAHBCO_01549	2.41e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HMCAHBCO_01550	1.73e-89	-	-	-	-	-	-	-	-
HMCAHBCO_01551	2.37e-123	-	-	-	-	-	-	-	-
HMCAHBCO_01552	5.92e-67	-	-	-	-	-	-	-	-
HMCAHBCO_01553	4.81e-76	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HMCAHBCO_01554	1.21e-111	-	-	-	-	-	-	-	-
HMCAHBCO_01555	1.76e-280	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HMCAHBCO_01556	5.33e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMCAHBCO_01557	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
HMCAHBCO_01558	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HMCAHBCO_01559	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HMCAHBCO_01560	7.02e-126	-	-	-	K	-	-	-	Helix-turn-helix domain
HMCAHBCO_01561	3.91e-283	-	-	-	C	-	-	-	FAD dependent oxidoreductase
HMCAHBCO_01562	1.82e-220	-	-	-	P	-	-	-	Major Facilitator Superfamily
HMCAHBCO_01563	3.16e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HMCAHBCO_01564	2.32e-43	ygzD	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
HMCAHBCO_01565	1.2e-91	-	-	-	-	-	-	-	-
HMCAHBCO_01566	1.05e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMCAHBCO_01567	5.3e-202	dkgB	-	-	S	-	-	-	reductase
HMCAHBCO_01568	6.07e-117	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HMCAHBCO_01569	2.02e-131	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC transporter permease
HMCAHBCO_01570	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HMCAHBCO_01571	1.5e-150	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HMCAHBCO_01572	4.77e-215	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HMCAHBCO_01573	7.76e-181	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HMCAHBCO_01574	2.38e-99	-	-	-	-	-	-	-	-
HMCAHBCO_01575	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HMCAHBCO_01576	2.4e-180	-	-	-	-	-	-	-	-
HMCAHBCO_01577	4.07e-05	-	-	-	-	-	-	-	-
HMCAHBCO_01578	5.66e-184	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HMCAHBCO_01579	1.67e-54	-	-	-	-	-	-	-	-
HMCAHBCO_01580	4.29e-166	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMCAHBCO_01581	9.79e-192	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HMCAHBCO_01582	1.84e-235	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
HMCAHBCO_01583	1.15e-155	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
HMCAHBCO_01584	7.9e-306	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
HMCAHBCO_01585	1.78e-160	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
HMCAHBCO_01586	3.58e-174	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HMCAHBCO_01587	1.19e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HMCAHBCO_01588	2.6e-193	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
HMCAHBCO_01589	7.11e-227	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HMCAHBCO_01590	1.87e-175	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HMCAHBCO_01591	7.44e-192	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HMCAHBCO_01592	1.61e-144	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HMCAHBCO_01593	1.45e-261	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HMCAHBCO_01594	2.39e-174	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HMCAHBCO_01595	0.0	-	-	-	L	-	-	-	HIRAN domain
HMCAHBCO_01596	1.24e-109	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HMCAHBCO_01597	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HMCAHBCO_01598	5.18e-159	-	-	-	-	-	-	-	-
HMCAHBCO_01599	2.07e-191	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HMCAHBCO_01600	0.0	pacL1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HMCAHBCO_01601	1.34e-183	-	-	-	F	-	-	-	Phosphorylase superfamily
HMCAHBCO_01602	2.92e-38	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HMCAHBCO_01603	1.72e-142	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HMCAHBCO_01604	1.27e-98	-	-	-	K	-	-	-	Transcriptional regulator
HMCAHBCO_01605	3.99e-96	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HMCAHBCO_01606	5.51e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HMCAHBCO_01607	5.38e-290	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HMCAHBCO_01608	3.98e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HMCAHBCO_01609	2.79e-274	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HMCAHBCO_01611	2.16e-204	morA	-	-	S	-	-	-	reductase
HMCAHBCO_01612	8.21e-213	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo keto reductase
HMCAHBCO_01613	1.92e-106	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase like
HMCAHBCO_01614	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HMCAHBCO_01615	7.45e-103	-	-	-	-	-	-	-	-
HMCAHBCO_01616	0.0	-	-	-	-	-	-	-	-
HMCAHBCO_01617	6.49e-268	-	-	-	C	-	-	-	Oxidoreductase
HMCAHBCO_01618	3.28e-193	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HMCAHBCO_01619	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HMCAHBCO_01620	2.57e-128	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HMCAHBCO_01622	4.37e-167	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HMCAHBCO_01623	4.14e-72	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HMCAHBCO_01624	2.09e-171	-	-	-	-	-	-	-	-
HMCAHBCO_01625	1.57e-191	-	-	-	-	-	-	-	-
HMCAHBCO_01626	3.37e-115	-	-	-	-	-	-	-	-
HMCAHBCO_01627	1.01e-184	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HMCAHBCO_01628	6.03e-218	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HMCAHBCO_01629	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
HMCAHBCO_01630	8.03e-151	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HMCAHBCO_01631	0.0	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
HMCAHBCO_01632	9.67e-98	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HMCAHBCO_01634	5.29e-121	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMCAHBCO_01635	2.35e-243	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
HMCAHBCO_01636	3.05e-236	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
HMCAHBCO_01637	7.88e-131	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
HMCAHBCO_01638	6.76e-75	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
HMCAHBCO_01639	2.32e-171	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HMCAHBCO_01640	2.65e-245	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HMCAHBCO_01641	1.83e-231	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HMCAHBCO_01642	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HMCAHBCO_01643	4.15e-191	yxeH	-	-	S	-	-	-	hydrolase
HMCAHBCO_01644	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HMCAHBCO_01645	1.14e-202	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
HMCAHBCO_01646	2.87e-101	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HMCAHBCO_01647	2.96e-89	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HMCAHBCO_01648	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HMCAHBCO_01649	5.84e-312	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HMCAHBCO_01650	2.28e-290	sdaC	-	-	E	ko:K03837	-	ko00000,ko02000	amino acid
HMCAHBCO_01651	7.51e-159	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HMCAHBCO_01652	2.81e-202	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HMCAHBCO_01653	6.59e-170	-	-	-	S	-	-	-	YheO-like PAS domain
HMCAHBCO_01654	4.01e-36	-	-	-	-	-	-	-	-
HMCAHBCO_01655	2.08e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMCAHBCO_01656	1.26e-305	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HMCAHBCO_01657	1.91e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HMCAHBCO_01658	2.57e-274	-	-	-	J	-	-	-	translation release factor activity
HMCAHBCO_01659	3.14e-164	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HMCAHBCO_01660	5.35e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HMCAHBCO_01661	1.6e-194	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HMCAHBCO_01662	1.84e-189	-	-	-	-	-	-	-	-
HMCAHBCO_01663	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HMCAHBCO_01664	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HMCAHBCO_01665	9.32e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HMCAHBCO_01666	4.79e-273	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HMCAHBCO_01667	2.58e-85	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HMCAHBCO_01668	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HMCAHBCO_01669	1.37e-248	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	ABC transporter, substratebinding protein
HMCAHBCO_01670	3.03e-202	-	-	-	U	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMCAHBCO_01671	5.79e-171	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HMCAHBCO_01672	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HMCAHBCO_01673	7.48e-260	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HMCAHBCO_01674	8.87e-245	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HMCAHBCO_01675	2.29e-292	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HMCAHBCO_01676	2.36e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HMCAHBCO_01677	3.52e-273	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
HMCAHBCO_01678	1.52e-240	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HMCAHBCO_01679	1.3e-110	queT	-	-	S	-	-	-	QueT transporter
HMCAHBCO_01680	1.4e-147	-	-	-	S	-	-	-	(CBS) domain
HMCAHBCO_01681	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HMCAHBCO_01682	2.79e-226	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HMCAHBCO_01683	1.43e-129	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HMCAHBCO_01684	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HMCAHBCO_01685	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HMCAHBCO_01686	7.72e-57	yabO	-	-	J	-	-	-	S4 domain protein
HMCAHBCO_01688	2.02e-83	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HMCAHBCO_01689	1.07e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HMCAHBCO_01690	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HMCAHBCO_01691	4.3e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HMCAHBCO_01692	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HMCAHBCO_01693	1.93e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HMCAHBCO_01694	5.33e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMCAHBCO_01695	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HMCAHBCO_01696	7.81e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HMCAHBCO_01697	3.04e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HMCAHBCO_01698	1.79e-243	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HMCAHBCO_01699	3.44e-204	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HMCAHBCO_01700	1.88e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HMCAHBCO_01701	1.54e-141	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HMCAHBCO_01702	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
HMCAHBCO_01703	3.04e-174	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HMCAHBCO_01704	4.07e-249	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HMCAHBCO_01705	3.76e-245	ampC	-	-	V	-	-	-	Beta-lactamase
HMCAHBCO_01706	8.57e-41	-	-	-	-	-	-	-	-
HMCAHBCO_01707	1.9e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HMCAHBCO_01708	1.33e-77	-	-	-	-	-	-	-	-
HMCAHBCO_01709	1.08e-181	-	-	-	-	-	-	-	-
HMCAHBCO_01710	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HMCAHBCO_01711	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HMCAHBCO_01712	1.81e-85	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HMCAHBCO_01713	2.91e-177	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
HMCAHBCO_01715	2.93e-73	-	-	-	V	-	-	-	Abortive infection bacteriophage resistance protein
HMCAHBCO_01716	5.11e-59	-	-	-	S	-	-	-	Bacteriophage holin
HMCAHBCO_01717	8.04e-245	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HMCAHBCO_01719	1.4e-27	-	-	-	-	-	-	-	-
HMCAHBCO_01720	1.4e-108	-	-	-	-	-	-	-	-
HMCAHBCO_01724	8.28e-127	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
HMCAHBCO_01725	2.64e-220	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HMCAHBCO_01726	0.0	-	-	-	M	-	-	-	Prophage endopeptidase tail
HMCAHBCO_01727	9.72e-173	-	-	-	S	-	-	-	phage tail
HMCAHBCO_01728	0.0	-	-	-	D	-	-	-	domain protein
HMCAHBCO_01730	5.37e-107	-	-	-	S	-	-	-	Phage tail assembly chaperone protein, TAC
HMCAHBCO_01731	2.09e-123	-	-	-	-	-	-	-	-
HMCAHBCO_01732	5.59e-81	-	-	-	-	-	-	-	-
HMCAHBCO_01733	9.66e-123	-	-	-	-	-	-	-	-
HMCAHBCO_01734	5.46e-67	-	-	-	-	-	-	-	-
HMCAHBCO_01735	3.11e-75	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HMCAHBCO_01736	2.45e-247	gpG	-	-	-	-	-	-	-
HMCAHBCO_01737	2.66e-110	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
HMCAHBCO_01738	5.76e-216	-	-	-	S	-	-	-	Phage Mu protein F like protein
HMCAHBCO_01739	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HMCAHBCO_01740	2.91e-316	-	-	-	S	ko:K06909	-	ko00000	Phage terminase, large subunit
HMCAHBCO_01742	3.13e-98	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
HMCAHBCO_01745	7.56e-25	-	-	-	-	-	-	-	-
HMCAHBCO_01746	1.15e-40	-	-	-	S	-	-	-	ASCH
HMCAHBCO_01747	2.49e-97	-	-	-	K	-	-	-	acetyltransferase
HMCAHBCO_01752	3.54e-18	-	-	-	S	-	-	-	YopX protein
HMCAHBCO_01754	1.44e-20	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HMCAHBCO_01755	3.24e-67	-	-	-	-	-	-	-	-
HMCAHBCO_01756	7.28e-213	-	-	-	L	-	-	-	DnaD domain protein
HMCAHBCO_01757	6.45e-80	-	-	-	-	-	-	-	-
HMCAHBCO_01758	8e-70	-	-	-	S	-	-	-	Bacteriophage Mu Gam like protein
HMCAHBCO_01760	2.15e-110	-	-	-	-	-	-	-	-
HMCAHBCO_01761	6.59e-72	-	-	-	-	-	-	-	-
HMCAHBCO_01763	7.19e-51	-	-	-	K	-	-	-	Helix-turn-helix
HMCAHBCO_01764	2.67e-80	-	-	-	K	-	-	-	Helix-turn-helix domain
HMCAHBCO_01765	1.92e-97	-	-	-	E	-	-	-	IrrE N-terminal-like domain
HMCAHBCO_01766	2.69e-38	-	-	-	S	-	-	-	TerB N-terminal domain
HMCAHBCO_01768	4.23e-19	-	-	-	S	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HMCAHBCO_01772	9.38e-279	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HMCAHBCO_01773	1.97e-110	-	-	-	S	-	-	-	Pfam:DUF3816
HMCAHBCO_01774	1.21e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HMCAHBCO_01775	1.27e-143	-	-	-	-	-	-	-	-
HMCAHBCO_01776	1.08e-229	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HMCAHBCO_01777	3.84e-185	-	-	-	S	-	-	-	Peptidase_C39 like family
HMCAHBCO_01778	1.04e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HMCAHBCO_01779	3.38e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HMCAHBCO_01780	9.38e-189	-	-	-	KT	-	-	-	helix_turn_helix, mercury resistance
HMCAHBCO_01781	3.41e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HMCAHBCO_01782	1.86e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HMCAHBCO_01783	1.2e-240	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HMCAHBCO_01784	1.18e-155	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMCAHBCO_01785	2.76e-117	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
HMCAHBCO_01786	5.72e-238	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HMCAHBCO_01787	3.55e-127	ywjB	-	-	H	-	-	-	RibD C-terminal domain
HMCAHBCO_01788	9.35e-257	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HMCAHBCO_01789	7.1e-152	-	-	-	S	-	-	-	Membrane
HMCAHBCO_01790	2.11e-199	mleP3	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HMCAHBCO_01791	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
HMCAHBCO_01792	4.32e-261	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HMCAHBCO_01793	7.22e-163	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HMCAHBCO_01794	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HMCAHBCO_01795	4.03e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HMCAHBCO_01796	8.99e-133	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HMCAHBCO_01797	2.17e-222	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HMCAHBCO_01798	5.9e-194	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HMCAHBCO_01799	0.0	tagE5	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
HMCAHBCO_01800	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HMCAHBCO_01802	2.24e-78	-	-	-	M	-	-	-	LysM domain
HMCAHBCO_01803	6.5e-119	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
HMCAHBCO_01804	1.65e-212	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMCAHBCO_01805	3.91e-269	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HMCAHBCO_01806	6.27e-166	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HMCAHBCO_01807	4.72e-72	cmd	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HMCAHBCO_01808	4.77e-100	yphH	-	-	S	-	-	-	Cupin domain
HMCAHBCO_01809	5.19e-103	-	-	-	K	-	-	-	transcriptional regulator, MerR family
HMCAHBCO_01810	4.87e-298	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HMCAHBCO_01811	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HMCAHBCO_01812	1.74e-156	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMCAHBCO_01814	1.19e-150	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HMCAHBCO_01815	3.18e-141	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HMCAHBCO_01816	1.03e-150	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HMCAHBCO_01818	4.86e-111	-	-	-	-	-	-	-	-
HMCAHBCO_01819	1.04e-110	yvbK	-	-	K	-	-	-	GNAT family
HMCAHBCO_01820	9.76e-50	-	-	-	-	-	-	-	-
HMCAHBCO_01821	2.81e-64	-	-	-	-	-	-	-	-
HMCAHBCO_01822	7.44e-143	pgm8	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
HMCAHBCO_01823	6.09e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
HMCAHBCO_01824	1.51e-200	-	-	-	K	-	-	-	LysR substrate binding domain
HMCAHBCO_01825	1.52e-135	-	-	-	GM	-	-	-	NAD(P)H-binding
HMCAHBCO_01826	1.66e-247	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HMCAHBCO_01827	2.9e-194	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HMCAHBCO_01828	1.28e-45	-	-	-	-	-	-	-	-
HMCAHBCO_01829	2.1e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HMCAHBCO_01830	2.09e-124	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HMCAHBCO_01831	1.76e-162	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HMCAHBCO_01832	1.03e-40	-	-	-	-	-	-	-	-
HMCAHBCO_01833	0.0	-	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
HMCAHBCO_01834	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HMCAHBCO_01836	9.45e-160	-	-	-	S	-	-	-	YjbR
HMCAHBCO_01837	4.04e-37	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HMCAHBCO_01838	3.23e-215	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HMCAHBCO_01839	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HMCAHBCO_01840	1.44e-255	glmS2	-	-	M	-	-	-	SIS domain
HMCAHBCO_01841	2.07e-35	-	-	-	S	-	-	-	Belongs to the LOG family
HMCAHBCO_01842	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HMCAHBCO_01843	3.98e-315	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HMCAHBCO_01844	5.85e-92	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HMCAHBCO_01845	5.38e-92	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HMCAHBCO_01846	4.75e-112	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
HMCAHBCO_01847	1.07e-206	-	-	-	GM	-	-	-	NmrA-like family
HMCAHBCO_01848	2.14e-86	-	-	-	K	ko:K22296	-	ko00000,ko03000	Winged helix DNA-binding domain
HMCAHBCO_01849	9.97e-94	spxA	-	-	P	ko:K16509	-	ko00000	ArsC family
HMCAHBCO_01850	3.46e-87	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HMCAHBCO_01851	1.7e-70	-	-	-	-	-	-	-	-
HMCAHBCO_01852	4.98e-275	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
HMCAHBCO_01853	2.11e-82	-	-	-	-	-	-	-	-
HMCAHBCO_01854	1.36e-112	-	-	-	-	-	-	-	-
HMCAHBCO_01855	4.58e-103	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HMCAHBCO_01856	3.78e-73	-	-	-	-	-	-	-	-
HMCAHBCO_01857	4.79e-21	-	-	-	-	-	-	-	-
HMCAHBCO_01858	3.57e-150	-	-	-	GM	-	-	-	NmrA-like family
HMCAHBCO_01859	2.52e-107	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HMCAHBCO_01860	9.43e-203	-	-	-	EG	-	-	-	EamA-like transporter family
HMCAHBCO_01861	2.66e-155	-	-	-	S	-	-	-	membrane
HMCAHBCO_01862	1.47e-144	-	-	-	S	-	-	-	VIT family
HMCAHBCO_01863	4.38e-243	pva2	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HMCAHBCO_01864	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HMCAHBCO_01865	8.01e-97	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HMCAHBCO_01866	4.26e-54	-	-	-	-	-	-	-	-
HMCAHBCO_01867	3.43e-96	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
HMCAHBCO_01868	8.8e-315	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HMCAHBCO_01869	7.21e-35	-	-	-	-	-	-	-	-
HMCAHBCO_01870	2.55e-65	-	-	-	-	-	-	-	-
HMCAHBCO_01871	2.51e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF1398)
HMCAHBCO_01872	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HMCAHBCO_01873	1.77e-282	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HMCAHBCO_01874	9.92e-230	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HMCAHBCO_01875	6.1e-101	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HMCAHBCO_01876	1.14e-110	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HMCAHBCO_01877	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HMCAHBCO_01878	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HMCAHBCO_01879	2.3e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HMCAHBCO_01880	1.36e-209	yvgN	-	-	C	-	-	-	Aldo keto reductase
HMCAHBCO_01881	2.57e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
HMCAHBCO_01882	1.7e-101	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HMCAHBCO_01883	1.5e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HMCAHBCO_01884	2.69e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HMCAHBCO_01885	5.94e-118	ymdB	-	-	S	-	-	-	Macro domain protein
HMCAHBCO_01886	6.47e-124	-	-	-	K	ko:K22041	-	ko00000,ko03000	transcriptional regulator
HMCAHBCO_01887	1.58e-66	-	-	-	-	-	-	-	-
HMCAHBCO_01888	2.41e-212	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HMCAHBCO_01889	0.0	-	-	-	-	-	-	-	-
HMCAHBCO_01890	2.08e-161	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HMCAHBCO_01891	1.56e-262	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
HMCAHBCO_01892	0.0	-	-	-	-	-	-	-	-
HMCAHBCO_01893	1.45e-260	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HMCAHBCO_01894	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HMCAHBCO_01895	1.91e-66	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HMCAHBCO_01896	8.61e-132	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HMCAHBCO_01897	7.04e-108	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HMCAHBCO_01898	1.05e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HMCAHBCO_01899	2.1e-161	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HMCAHBCO_01900	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HMCAHBCO_01901	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HMCAHBCO_01902	8.43e-240	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HMCAHBCO_01903	1.18e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HMCAHBCO_01904	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HMCAHBCO_01905	1.8e-135	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HMCAHBCO_01906	1.29e-200	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HMCAHBCO_01907	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMCAHBCO_01908	9.34e-201	-	-	-	S	-	-	-	Tetratricopeptide repeat
HMCAHBCO_01909	4.38e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HMCAHBCO_01910	3.21e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HMCAHBCO_01911	7.8e-300	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HMCAHBCO_01912	9.6e-143	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HMCAHBCO_01913	1.3e-65	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HMCAHBCO_01914	6.47e-95	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HMCAHBCO_01915	5.12e-31	-	-	-	-	-	-	-	-
HMCAHBCO_01916	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HMCAHBCO_01917	3.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HMCAHBCO_01918	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HMCAHBCO_01919	8.45e-162	epsB	-	-	M	-	-	-	biosynthesis protein
HMCAHBCO_01920	2.02e-156	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HMCAHBCO_01921	5.54e-189	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HMCAHBCO_01922	8.71e-231	cps4D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HMCAHBCO_01923	3.18e-162	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
HMCAHBCO_01924	1.43e-223	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
HMCAHBCO_01925	1.82e-132	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
HMCAHBCO_01926	7.88e-48	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
HMCAHBCO_01927	1.91e-297	-	-	-	-	-	-	-	-
HMCAHBCO_01928	4.82e-228	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
HMCAHBCO_01929	0.0	cps4J	-	-	S	-	-	-	MatE
HMCAHBCO_01930	0.0	-	3.1.4.53	-	S	ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HMCAHBCO_01931	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HMCAHBCO_01932	4.24e-218	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HMCAHBCO_01933	3.02e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HMCAHBCO_01934	1.55e-311	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HMCAHBCO_01935	6.62e-62	-	-	-	-	-	-	-	-
HMCAHBCO_01936	8.34e-228	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HMCAHBCO_01937	7.09e-180	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HMCAHBCO_01938	1.84e-67	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HMCAHBCO_01939	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HMCAHBCO_01940	1.52e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HMCAHBCO_01941	3.58e-129	-	-	-	K	-	-	-	Helix-turn-helix domain
HMCAHBCO_01942	1.66e-269	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HMCAHBCO_01943	2.84e-75	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
HMCAHBCO_01944	2.21e-178	-	-	-	Q	-	-	-	Methyltransferase
HMCAHBCO_01945	5.03e-43	-	-	-	-	-	-	-	-
HMCAHBCO_01946	3.5e-205	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HMCAHBCO_01947	2.97e-244	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HMCAHBCO_01948	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HMCAHBCO_01949	1.55e-230	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HMCAHBCO_01950	5.55e-100	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HMCAHBCO_01951	6.61e-29	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HMCAHBCO_01952	1.11e-33	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HMCAHBCO_01953	3.38e-50	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HMCAHBCO_01954	1.29e-235	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HMCAHBCO_01955	5.91e-297	-	-	-	P	ko:K06610	-	ko00000,ko02000	Major Facilitator Superfamily
HMCAHBCO_01956	0.0	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HMCAHBCO_01957	2.9e-293	-	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
HMCAHBCO_01958	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HMCAHBCO_01959	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HMCAHBCO_01960	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HMCAHBCO_01961	1.95e-140	aqpZ	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HMCAHBCO_01962	3.7e-279	-	-	-	S	-	-	-	associated with various cellular activities
HMCAHBCO_01963	9.34e-317	-	-	-	S	-	-	-	Putative metallopeptidase domain
HMCAHBCO_01964	1.03e-65	-	-	-	-	-	-	-	-
HMCAHBCO_01965	8.19e-134	yezE	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
HMCAHBCO_01966	7.83e-60	-	-	-	-	-	-	-	-
HMCAHBCO_01967	4.23e-129	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HMCAHBCO_01968	8.67e-160	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HMCAHBCO_01969	1.83e-235	-	-	-	S	-	-	-	Cell surface protein
HMCAHBCO_01970	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HMCAHBCO_01971	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HMCAHBCO_01972	1.06e-106	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HMCAHBCO_01973	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HMCAHBCO_01974	1.82e-152	rcfA	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HMCAHBCO_01975	2.98e-44	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
HMCAHBCO_01976	4.27e-126	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HMCAHBCO_01977	1.01e-26	-	-	-	-	-	-	-	-
HMCAHBCO_01978	4.82e-55	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
HMCAHBCO_01979	5.73e-73	trxA3	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
HMCAHBCO_01980	9.44e-183	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HMCAHBCO_01981	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HMCAHBCO_01982	8.06e-232	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HMCAHBCO_01983	1.5e-165	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
HMCAHBCO_01984	4.16e-175	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HMCAHBCO_01985	4.84e-230	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HMCAHBCO_01986	1.12e-134	-	-	-	K	-	-	-	transcriptional regulator
HMCAHBCO_01988	9.39e-84	-	-	-	-	-	-	-	-
HMCAHBCO_01990	5.77e-81	-	-	-	-	-	-	-	-
HMCAHBCO_01991	6.18e-71	-	-	-	-	-	-	-	-
HMCAHBCO_01992	1.88e-96	-	-	-	M	-	-	-	PFAM NLP P60 protein
HMCAHBCO_01993	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
HMCAHBCO_01994	4.45e-38	-	-	-	-	-	-	-	-
HMCAHBCO_01995	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HMCAHBCO_01996	3.81e-150	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMCAHBCO_01997	3.08e-113	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HMCAHBCO_01998	1.63e-176	yesN	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HMCAHBCO_01999	3.17e-170	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HMCAHBCO_02000	1.56e-71	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HMCAHBCO_02001	3.72e-14	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
HMCAHBCO_02002	9.51e-135	-	-	-	-	-	-	-	-
HMCAHBCO_02003	4.84e-227	-	-	-	-	-	-	-	-
HMCAHBCO_02004	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HMCAHBCO_02005	7.1e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HMCAHBCO_02006	2.64e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HMCAHBCO_02007	2.15e-209	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
HMCAHBCO_02008	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HMCAHBCO_02009	2.36e-285	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HMCAHBCO_02010	8.65e-228	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HMCAHBCO_02011	1.21e-268	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HMCAHBCO_02012	3.95e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HMCAHBCO_02013	6.45e-111	-	-	-	-	-	-	-	-
HMCAHBCO_02014	4.86e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HMCAHBCO_02015	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMCAHBCO_02016	3.45e-240	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HMCAHBCO_02017	2.16e-39	-	-	-	-	-	-	-	-
HMCAHBCO_02018	2.62e-168	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HMCAHBCO_02019	5.35e-220	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMCAHBCO_02020	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HMCAHBCO_02021	1.02e-155	-	-	-	S	-	-	-	repeat protein
HMCAHBCO_02022	2.41e-157	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HMCAHBCO_02023	0.0	-	-	-	N	-	-	-	domain, Protein
HMCAHBCO_02024	2.02e-247	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HMCAHBCO_02025	4.17e-153	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
HMCAHBCO_02026	4.64e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HMCAHBCO_02027	9.64e-307	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HMCAHBCO_02028	1.53e-284	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HMCAHBCO_02029	4.94e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HMCAHBCO_02030	8.09e-275	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HMCAHBCO_02031	5.85e-158	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HMCAHBCO_02032	7.74e-47	-	-	-	-	-	-	-	-
HMCAHBCO_02033	3.51e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HMCAHBCO_02034	3.46e-242	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HMCAHBCO_02035	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HMCAHBCO_02036	6.52e-124	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HMCAHBCO_02037	2.06e-187	ylmH	-	-	S	-	-	-	S4 domain protein
HMCAHBCO_02038	6.45e-49	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HMCAHBCO_02039	1.56e-93	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HMCAHBCO_02040	9.39e-295	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HMCAHBCO_02041	3.55e-312	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HMCAHBCO_02042	2.34e-208	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HMCAHBCO_02043	2.04e-252	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HMCAHBCO_02044	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HMCAHBCO_02045	2.81e-231	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HMCAHBCO_02046	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HMCAHBCO_02047	7.01e-76	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HMCAHBCO_02048	1.74e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HMCAHBCO_02049	7.24e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HMCAHBCO_02050	3.22e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
HMCAHBCO_02051	4.1e-223	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HMCAHBCO_02052	2.56e-131	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HMCAHBCO_02053	8.07e-163	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HMCAHBCO_02054	6.36e-134	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMCAHBCO_02055	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HMCAHBCO_02056	1.56e-108	-	-	-	-	-	-	-	-
HMCAHBCO_02057	5.97e-96	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HMCAHBCO_02058	9.2e-243	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HMCAHBCO_02059	7.3e-245	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMCAHBCO_02060	3.7e-30	-	-	-	-	-	-	-	-
HMCAHBCO_02061	1.38e-131	-	-	-	-	-	-	-	-
HMCAHBCO_02062	3.46e-210	-	-	-	K	-	-	-	LysR substrate binding domain
HMCAHBCO_02063	4.34e-314	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HMCAHBCO_02064	0.0	-	4.1.1.98	-	H	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HMCAHBCO_02065	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HMCAHBCO_02066	1.37e-182	-	-	-	S	-	-	-	zinc-ribbon domain
HMCAHBCO_02068	4.29e-50	-	-	-	-	-	-	-	-
HMCAHBCO_02069	1.4e-137	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HMCAHBCO_02070	1.4e-20	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HMCAHBCO_02071	2.35e-231	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HMCAHBCO_02072	0.0	-	-	-	I	-	-	-	acetylesterase activity
HMCAHBCO_02073	6.08e-78	-	-	-	M	-	-	-	Collagen binding domain
HMCAHBCO_02074	6.92e-206	yicL	-	-	EG	-	-	-	EamA-like transporter family
HMCAHBCO_02075	6.12e-166	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HMCAHBCO_02076	3.39e-225	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
HMCAHBCO_02077	5.93e-144	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HMCAHBCO_02078	5.07e-62	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HMCAHBCO_02079	3.06e-206	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HMCAHBCO_02080	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
HMCAHBCO_02081	9.86e-117	-	-	-	-	-	-	-	-
HMCAHBCO_02082	1.02e-164	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HMCAHBCO_02083	9.21e-234	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HMCAHBCO_02084	7.39e-121	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HMCAHBCO_02085	5.85e-204	ccpB	-	-	K	-	-	-	lacI family
HMCAHBCO_02086	2.21e-154	yceE	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HMCAHBCO_02087	8.08e-154	ydgI3	-	-	C	-	-	-	Nitroreductase family
HMCAHBCO_02088	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HMCAHBCO_02089	4.21e-150	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HMCAHBCO_02090	5.82e-198	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HMCAHBCO_02091	6.97e-216	XK27_00670	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HMCAHBCO_02092	0.0	-	-	-	-	-	-	-	-
HMCAHBCO_02093	4.71e-81	-	-	-	-	-	-	-	-
HMCAHBCO_02094	5.52e-242	-	-	-	S	-	-	-	Cell surface protein
HMCAHBCO_02095	1.27e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HMCAHBCO_02096	5.06e-82	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HMCAHBCO_02097	3.13e-42	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HMCAHBCO_02098	2.78e-158	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMCAHBCO_02099	5.21e-180	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
HMCAHBCO_02100	2.29e-193	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HMCAHBCO_02101	4.54e-191	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HMCAHBCO_02102	1.04e-269	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HMCAHBCO_02104	1.15e-43	-	-	-	-	-	-	-	-
HMCAHBCO_02105	4.54e-54	-	-	-	-	-	-	-	-
HMCAHBCO_02107	8.83e-317	-	-	-	EGP	-	-	-	Major Facilitator
HMCAHBCO_02108	5.61e-216	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HMCAHBCO_02109	4.26e-109	cvpA	-	-	S	-	-	-	Colicin V production protein
HMCAHBCO_02110	9.61e-84	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HMCAHBCO_02111	1.59e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HMCAHBCO_02112	1.8e-134	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HMCAHBCO_02113	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HMCAHBCO_02114	2.01e-134	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HMCAHBCO_02115	5.59e-271	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
HMCAHBCO_02116	3.91e-124	tag2	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HMCAHBCO_02117	8.03e-28	-	-	-	-	-	-	-	-
HMCAHBCO_02118	1.3e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HMCAHBCO_02119	7.27e-73	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HMCAHBCO_02120	2.94e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HMCAHBCO_02121	1.97e-60	qacH	-	-	U	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HMCAHBCO_02122	1.63e-77	-	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HMCAHBCO_02123	1.38e-275	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HMCAHBCO_02124	3.1e-228	ydbI	-	-	K	-	-	-	AI-2E family transporter
HMCAHBCO_02125	1.07e-211	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HMCAHBCO_02126	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HMCAHBCO_02128	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
HMCAHBCO_02129	4.62e-107	-	-	-	-	-	-	-	-
HMCAHBCO_02131	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMCAHBCO_02132	1.02e-187	ptp2	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HMCAHBCO_02133	4.17e-235	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HMCAHBCO_02134	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HMCAHBCO_02135	3.66e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HMCAHBCO_02136	2.05e-72	-	-	-	S	-	-	-	Enterocin A Immunity
HMCAHBCO_02137	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HMCAHBCO_02138	1.49e-253	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HMCAHBCO_02139	9.07e-233	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
HMCAHBCO_02140	2.85e-210	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
HMCAHBCO_02141	0.0	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
HMCAHBCO_02142	7.02e-151	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
HMCAHBCO_02143	1.03e-34	-	-	-	-	-	-	-	-
HMCAHBCO_02144	1.56e-185	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HMCAHBCO_02145	2.88e-164	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
HMCAHBCO_02146	4.14e-84	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
HMCAHBCO_02147	2.8e-135	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HMCAHBCO_02148	1.33e-100	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HMCAHBCO_02149	7.47e-77	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HMCAHBCO_02150	6.46e-49	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
HMCAHBCO_02151	1.28e-77	-	-	-	S	-	-	-	Enterocin A Immunity
HMCAHBCO_02152	1.55e-114	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HMCAHBCO_02153	1.16e-135	-	-	-	-	-	-	-	-
HMCAHBCO_02154	8.44e-304	-	-	-	S	-	-	-	module of peptide synthetase
HMCAHBCO_02155	2.95e-100	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HMCAHBCO_02157	1.25e-164	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
HMCAHBCO_02158	0.0	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HMCAHBCO_02159	7.54e-200	-	-	-	GM	-	-	-	NmrA-like family
HMCAHBCO_02160	4.08e-101	-	-	-	K	-	-	-	MerR family regulatory protein
HMCAHBCO_02161	2.81e-167	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
HMCAHBCO_02162	2.88e-106	gtcA3	-	-	S	-	-	-	GtrA-like protein
HMCAHBCO_02163	3.35e-157	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HMCAHBCO_02164	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HMCAHBCO_02165	1.18e-94	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
HMCAHBCO_02166	7.03e-62	-	-	-	-	-	-	-	-
HMCAHBCO_02167	1.81e-150	-	-	-	S	-	-	-	SNARE associated Golgi protein
HMCAHBCO_02168	8.58e-65	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HMCAHBCO_02169	7.89e-124	-	-	-	P	-	-	-	Cadmium resistance transporter
HMCAHBCO_02170	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMCAHBCO_02171	3.93e-38	-	-	-	P	-	-	-	Concanavalin A-like lectin/glucanases superfamily
HMCAHBCO_02173	2.03e-84	-	-	-	-	-	-	-	-
HMCAHBCO_02174	1.58e-204	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HMCAHBCO_02175	1.21e-73	-	-	-	-	-	-	-	-
HMCAHBCO_02176	1.24e-194	-	-	-	K	-	-	-	Helix-turn-helix domain
HMCAHBCO_02177	3.91e-100	pts23A	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HMCAHBCO_02178	7.47e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HMCAHBCO_02179	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMCAHBCO_02180	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HMCAHBCO_02181	4.32e-235	-	-	-	GM	-	-	-	Male sterility protein
HMCAHBCO_02182	2.1e-99	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HMCAHBCO_02183	4.61e-101	-	-	-	M	-	-	-	LysM domain
HMCAHBCO_02184	7.94e-126	-	-	-	M	-	-	-	Lysin motif
HMCAHBCO_02185	5.71e-138	-	-	-	S	-	-	-	SdpI/YhfL protein family
HMCAHBCO_02186	1.58e-72	nudA	-	-	S	-	-	-	ASCH
HMCAHBCO_02187	5.76e-212	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HMCAHBCO_02188	3.57e-120	-	-	-	-	-	-	-	-
HMCAHBCO_02189	1.92e-155	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
HMCAHBCO_02190	3.55e-281	-	-	-	T	-	-	-	diguanylate cyclase
HMCAHBCO_02191	7.43e-97	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HMCAHBCO_02192	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HMCAHBCO_02193	2.31e-277	-	-	-	-	-	-	-	-
HMCAHBCO_02194	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMCAHBCO_02195	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HMCAHBCO_02197	3.23e-290	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
HMCAHBCO_02198	2.96e-209	yhxD	-	-	IQ	-	-	-	KR domain
HMCAHBCO_02200	1.97e-92	-	-	-	-	-	-	-	-
HMCAHBCO_02201	1.43e-184	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HMCAHBCO_02202	0.0	-	-	-	E	-	-	-	Amino Acid
HMCAHBCO_02203	4.8e-86	lysM	-	-	M	-	-	-	LysM domain
HMCAHBCO_02204	4.2e-286	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HMCAHBCO_02205	6.8e-272	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
HMCAHBCO_02206	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HMCAHBCO_02207	1.23e-57	-	-	-	S	-	-	-	Cupredoxin-like domain
HMCAHBCO_02208	1.36e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
HMCAHBCO_02209	2.69e-316	dinF	-	-	V	-	-	-	MatE
HMCAHBCO_02210	1.79e-42	-	-	-	-	-	-	-	-
HMCAHBCO_02212	8.2e-102	yybD	-	-	S	ko:K02348	-	ko00000	Acetyltransferase (GNAT) domain
HMCAHBCO_02213	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HMCAHBCO_02214	4.64e-106	-	-	-	-	-	-	-	-
HMCAHBCO_02215	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HMCAHBCO_02216	1.04e-136	-	-	-	-	-	-	-	-
HMCAHBCO_02217	0.0	celR	-	-	K	-	-	-	PRD domain
HMCAHBCO_02218	1.34e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HMCAHBCO_02219	2.37e-68	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HMCAHBCO_02220	4.9e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HMCAHBCO_02221	1.71e-277	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMCAHBCO_02222	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HMCAHBCO_02223	3.5e-271	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
HMCAHBCO_02224	2.34e-146	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HMCAHBCO_02225	1.65e-46	dltC2	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMCAHBCO_02226	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	Alanine-glyoxylate amino-transferase
HMCAHBCO_02227	8.08e-133	argO	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
HMCAHBCO_02228	5.58e-271	arcT	-	-	E	-	-	-	Aminotransferase
HMCAHBCO_02229	2.07e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HMCAHBCO_02230	2.43e-18	-	-	-	-	-	-	-	-
HMCAHBCO_02231	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HMCAHBCO_02232	9.94e-71	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HMCAHBCO_02233	4.47e-296	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HMCAHBCO_02234	0.0	yhaN	-	-	L	-	-	-	AAA domain
HMCAHBCO_02235	1.03e-240	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HMCAHBCO_02236	1.05e-272	-	-	-	-	-	-	-	-
HMCAHBCO_02237	2.41e-233	-	-	-	M	-	-	-	Peptidase family S41
HMCAHBCO_02238	1.09e-225	-	-	-	K	-	-	-	LysR substrate binding domain
HMCAHBCO_02239	9.9e-144	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HMCAHBCO_02240	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HMCAHBCO_02241	4.43e-129	-	-	-	-	-	-	-	-
HMCAHBCO_02242	1.17e-100	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
HMCAHBCO_02243	1.15e-235	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
HMCAHBCO_02244	7.78e-20	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HMCAHBCO_02245	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HMCAHBCO_02246	4.29e-26	-	-	-	S	-	-	-	NUDIX domain
HMCAHBCO_02247	0.0	-	-	-	S	-	-	-	membrane
HMCAHBCO_02248	4.26e-218	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HMCAHBCO_02249	2.61e-95	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HMCAHBCO_02250	2.08e-284	ribA	3.5.4.25, 4.1.99.12	-	H	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HMCAHBCO_02251	1.23e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HMCAHBCO_02252	5.21e-137	-	-	-	S	ko:K09962	-	ko00000	Nucleotidyltransferase
HMCAHBCO_02253	1.96e-137	-	-	-	-	-	-	-	-
HMCAHBCO_02254	3.3e-151	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HMCAHBCO_02255	1.08e-95	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMCAHBCO_02256	6.01e-49	-	-	-	S	-	-	-	Bacteriophage holin
HMCAHBCO_02257	3.12e-201	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HMCAHBCO_02258	2.91e-29	-	-	-	-	-	-	-	-
HMCAHBCO_02259	1.93e-102	-	-	-	-	-	-	-	-
HMCAHBCO_02263	2.03e-92	-	-	-	S	-	-	-	Phage minor structural protein
HMCAHBCO_02264	2.29e-79	-	-	-	S	-	-	-	Phage tail protein
HMCAHBCO_02265	6.77e-155	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
HMCAHBCO_02267	6.36e-34	-	-	-	-	-	-	-	-
HMCAHBCO_02268	1.35e-75	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
HMCAHBCO_02269	2.16e-131	-	-	-	S	-	-	-	Phage tail tube protein
HMCAHBCO_02270	7.47e-74	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
HMCAHBCO_02271	2.25e-86	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HMCAHBCO_02272	3.45e-76	-	-	-	S	-	-	-	Phage head-tail joining protein
HMCAHBCO_02273	9.36e-65	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HMCAHBCO_02274	1.03e-254	-	-	-	S	-	-	-	Phage capsid family
HMCAHBCO_02275	5.99e-164	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HMCAHBCO_02276	6.97e-284	-	-	-	S	-	-	-	Phage portal protein
HMCAHBCO_02277	6.68e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF1056)
HMCAHBCO_02278	0.0	-	-	-	S	-	-	-	Phage Terminase
HMCAHBCO_02279	6.68e-103	-	-	-	L	-	-	-	Phage terminase, small subunit
HMCAHBCO_02281	7.81e-113	-	-	-	L	-	-	-	HNH nucleases
HMCAHBCO_02282	1.13e-84	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
HMCAHBCO_02283	2.2e-23	-	-	-	-	-	-	-	-
HMCAHBCO_02284	5.27e-72	-	-	-	-	-	-	-	-
HMCAHBCO_02285	1.28e-09	-	-	-	S	-	-	-	YopX protein
HMCAHBCO_02287	8.89e-118	-	-	-	L	-	-	-	C-5 cytosine-specific DNA methylase
HMCAHBCO_02289	2.95e-06	-	-	-	-	-	-	-	-
HMCAHBCO_02290	1.01e-20	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HMCAHBCO_02292	2.84e-169	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
HMCAHBCO_02293	3.13e-127	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
HMCAHBCO_02294	3.98e-151	-	-	-	S	-	-	-	AAA domain
HMCAHBCO_02295	4.24e-188	-	-	-	S	-	-	-	Protein of unknown function (DUF1351)
HMCAHBCO_02297	2e-25	-	-	-	-	-	-	-	-
HMCAHBCO_02302	7.34e-80	-	-	-	S	-	-	-	DNA binding
HMCAHBCO_02305	1.56e-27	-	-	-	-	-	-	-	-
HMCAHBCO_02306	2.59e-99	-	-	-	K	-	-	-	Peptidase S24-like
HMCAHBCO_02313	1.63e-68	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HMCAHBCO_02314	6.48e-135	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HMCAHBCO_02315	8.68e-118	pts21A	-	-	G	ko:K02755	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HMCAHBCO_02316	2e-52	-	-	-	S	-	-	-	Cytochrome B5
HMCAHBCO_02317	0.0	-	-	-	-	-	-	-	-
HMCAHBCO_02318	1.01e-167	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HMCAHBCO_02319	9.55e-205	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HMCAHBCO_02320	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HMCAHBCO_02321	1.76e-298	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HMCAHBCO_02322	1.54e-219	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HMCAHBCO_02323	1.35e-264	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HMCAHBCO_02324	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
HMCAHBCO_02325	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HMCAHBCO_02326	5.69e-191	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HMCAHBCO_02327	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HMCAHBCO_02328	2.09e-287	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HMCAHBCO_02329	8.76e-126	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HMCAHBCO_02330	1.39e-134	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HMCAHBCO_02331	4.36e-197	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HMCAHBCO_02332	6.88e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HMCAHBCO_02333	1.23e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
HMCAHBCO_02334	2.06e-313	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HMCAHBCO_02339	6.27e-316	-	-	-	EGP	-	-	-	Major Facilitator
HMCAHBCO_02340	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMCAHBCO_02341	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMCAHBCO_02343	1.8e-249	-	-	-	C	-	-	-	Aldo/keto reductase family
HMCAHBCO_02344	1.07e-131	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HMCAHBCO_02345	2.33e-283	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HMCAHBCO_02346	3.73e-131	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HMCAHBCO_02347	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HMCAHBCO_02348	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HMCAHBCO_02349	1.08e-221	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
HMCAHBCO_02350	0.0	treP	2.4.1.64	GH65	G	ko:K05342	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HMCAHBCO_02351	1.3e-203	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HMCAHBCO_02352	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HMCAHBCO_02353	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HMCAHBCO_02354	2.62e-216	pbg9	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HMCAHBCO_02355	3.72e-200	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HMCAHBCO_02356	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HMCAHBCO_02357	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HMCAHBCO_02358	2.26e-269	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HMCAHBCO_02359	6.87e-202	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
HMCAHBCO_02360	1.67e-208	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HMCAHBCO_02361	0.0	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMCAHBCO_02362	5.44e-174	-	-	-	K	-	-	-	UTRA domain
HMCAHBCO_02363	1.78e-198	estA	-	-	S	-	-	-	Putative esterase
HMCAHBCO_02364	2.97e-83	-	-	-	-	-	-	-	-
HMCAHBCO_02365	5.78e-269	-	-	-	G	-	-	-	Major Facilitator Superfamily
HMCAHBCO_02366	5.79e-209	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HMCAHBCO_02367	1.66e-215	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HMCAHBCO_02368	1.33e-274	-	-	-	G	-	-	-	Transporter
HMCAHBCO_02369	5.56e-167	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HMCAHBCO_02370	1.23e-228	apbE3	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HMCAHBCO_02371	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HMCAHBCO_02372	2.86e-85	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
HMCAHBCO_02373	1.42e-245	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HMCAHBCO_02374	3.69e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HMCAHBCO_02375	3.51e-252	galM3	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HMCAHBCO_02376	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HMCAHBCO_02377	6.39e-169	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HMCAHBCO_02378	8.05e-166	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HMCAHBCO_02379	1.9e-230	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
HMCAHBCO_02380	2.26e-209	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HMCAHBCO_02381	6.87e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HMCAHBCO_02382	1.19e-201	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HMCAHBCO_02383	1.6e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HMCAHBCO_02384	1.63e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HMCAHBCO_02386	2.53e-106	mutR	-	-	K	ko:K20373,ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
HMCAHBCO_02387	1.81e-273	-	-	-	EGP	ko:K02030	-	ko00000,ko00002,ko02000	Drug resistance transporter Bcr CflA subfamily
HMCAHBCO_02388	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HMCAHBCO_02389	4.64e-92	-	-	-	F	-	-	-	DNA mismatch repair protein MutT
HMCAHBCO_02390	1.12e-205	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HMCAHBCO_02391	3.56e-170	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HMCAHBCO_02392	7.71e-228	-	-	-	-	-	-	-	-
HMCAHBCO_02393	1.37e-290	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HMCAHBCO_02394	1.36e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HMCAHBCO_02395	4.87e-243	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMCAHBCO_02396	1.6e-77	chpA	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HMCAHBCO_02397	5.9e-46	-	-	-	-	-	-	-	-
HMCAHBCO_02398	1.69e-97	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HMCAHBCO_02399	9.68e-34	-	-	-	-	-	-	-	-
HMCAHBCO_02400	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMCAHBCO_02401	2.69e-166	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HMCAHBCO_02402	2.35e-243	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HMCAHBCO_02403	1.38e-179	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HMCAHBCO_02404	0.0	-	-	-	L	-	-	-	DNA helicase
HMCAHBCO_02405	4.23e-64	axe	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
HMCAHBCO_02406	3.74e-144	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HMCAHBCO_02407	4.56e-144	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HMCAHBCO_02408	8.02e-152	plnU	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HMCAHBCO_02409	2.6e-140	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HMCAHBCO_02410	1.17e-306	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
HMCAHBCO_02411	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HMCAHBCO_02412	2.59e-19	-	-	-	-	-	-	-	-
HMCAHBCO_02413	1.93e-31	plnF	-	-	-	-	-	-	-
HMCAHBCO_02414	8.15e-167	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HMCAHBCO_02415	1.17e-60	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HMCAHBCO_02416	6.27e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HMCAHBCO_02417	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HMCAHBCO_02418	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HMCAHBCO_02419	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HMCAHBCO_02420	3.97e-229	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HMCAHBCO_02421	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HMCAHBCO_02422	4.71e-210	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HMCAHBCO_02423	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HMCAHBCO_02424	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HMCAHBCO_02425	1.63e-163	mleR	-	-	K	-	-	-	LysR substrate binding domain
HMCAHBCO_02426	5.44e-35	mleR	-	-	K	-	-	-	LysR substrate binding domain
HMCAHBCO_02427	0.0	-	-	-	M	-	-	-	domain protein
HMCAHBCO_02429	1.03e-201	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HMCAHBCO_02430	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HMCAHBCO_02431	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HMCAHBCO_02432	2.65e-102	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HMCAHBCO_02433	1.45e-278	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMCAHBCO_02434	1.24e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HMCAHBCO_02435	6.7e-148	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
HMCAHBCO_02436	3.38e-227	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HMCAHBCO_02437	6.33e-46	-	-	-	-	-	-	-	-
HMCAHBCO_02438	1.15e-79	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HMCAHBCO_02439	4.37e-208	fbpA	-	-	K	-	-	-	Domain of unknown function (DUF814)
HMCAHBCO_02440	1.29e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMCAHBCO_02441	3.81e-18	-	-	-	-	-	-	-	-
HMCAHBCO_02442	3.18e-77	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMCAHBCO_02443	5.66e-74	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMCAHBCO_02444	2.2e-280	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
HMCAHBCO_02445	1.5e-104	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMCAHBCO_02446	5.55e-22	-	-	-	G	ko:K11203	-	ko00000,ko00002,ko02000	PTS system, fructose subfamily
HMCAHBCO_02447	2.52e-35	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HMCAHBCO_02448	9.49e-155	fptC	-	-	U	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase system, EIIC
HMCAHBCO_02449	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
HMCAHBCO_02450	2.24e-116	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HMCAHBCO_02451	3.54e-190	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HMCAHBCO_02452	2.69e-194	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
HMCAHBCO_02453	6.26e-101	-	-	-	-	-	-	-	-
HMCAHBCO_02454	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMCAHBCO_02455	2.93e-151	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMCAHBCO_02456	2.44e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HMCAHBCO_02457	3.73e-263	-	-	-	S	-	-	-	DUF218 domain
HMCAHBCO_02458	1.06e-232	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HMCAHBCO_02459	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HMCAHBCO_02460	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HMCAHBCO_02461	1.6e-200	-	-	-	S	-	-	-	Putative adhesin
HMCAHBCO_02462	1.73e-132	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HMCAHBCO_02463	2.86e-68	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
HMCAHBCO_02464	1.07e-127	-	-	-	KT	-	-	-	response to antibiotic
HMCAHBCO_02465	1.26e-161	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HMCAHBCO_02466	3.02e-176	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HMCAHBCO_02467	2.11e-158	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMCAHBCO_02468	2.13e-167	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HMCAHBCO_02469	2.07e-302	-	-	-	EK	-	-	-	Aminotransferase, class I
HMCAHBCO_02470	3.36e-216	-	-	-	K	-	-	-	LysR substrate binding domain
HMCAHBCO_02471	3.66e-189	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HMCAHBCO_02472	2.89e-312	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HMCAHBCO_02473	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HMCAHBCO_02474	2.1e-33	-	-	-	-	-	-	-	-
HMCAHBCO_02475	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMCAHBCO_02476	1.89e-254	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HMCAHBCO_02477	2.62e-76	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HMCAHBCO_02478	0.0	-	3.6.3.44	-	P	ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
HMCAHBCO_02479	4.63e-24	-	-	-	-	-	-	-	-
HMCAHBCO_02480	1.25e-25	-	-	-	-	-	-	-	-
HMCAHBCO_02481	6.21e-26	-	-	-	-	-	-	-	-
HMCAHBCO_02482	6.21e-26	-	-	-	-	-	-	-	-
HMCAHBCO_02483	9.85e-22	-	-	-	-	-	-	-	-
HMCAHBCO_02484	2.69e-23	-	-	-	-	-	-	-	-
HMCAHBCO_02485	9.05e-22	-	-	-	-	-	-	-	-
HMCAHBCO_02486	2.55e-217	inlJ	-	-	M	-	-	-	MucBP domain
HMCAHBCO_02487	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
HMCAHBCO_02488	1.27e-109	-	-	-	K	-	-	-	MarR family
HMCAHBCO_02489	9.28e-58	-	-	-	-	-	-	-	-
HMCAHBCO_02490	1.28e-51	-	-	-	-	-	-	-	-
HMCAHBCO_02491	1.79e-289	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HMCAHBCO_02492	1.1e-06	-	-	-	K	ko:K07727	-	ko00000,ko03000	transcriptional regulator
HMCAHBCO_02495	2.62e-40	-	-	-	-	-	-	-	-
HMCAHBCO_02496	1.5e-187	-	-	-	L	-	-	-	DNA replication protein
HMCAHBCO_02497	0.0	-	-	-	S	-	-	-	Virulence-associated protein E
HMCAHBCO_02498	3.36e-96	-	-	-	-	-	-	-	-
HMCAHBCO_02500	3.24e-62	-	-	-	S	-	-	-	Head-tail joining protein
HMCAHBCO_02501	1.05e-88	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	Phage-associated protein
HMCAHBCO_02502	1.9e-109	terS	-	-	L	-	-	-	Phage terminase, small subunit
HMCAHBCO_02503	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
HMCAHBCO_02505	6.16e-260	-	-	-	S	-	-	-	Phage portal protein
HMCAHBCO_02506	0.0	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
HMCAHBCO_02507	1.75e-48	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HMCAHBCO_02508	1.02e-80	-	-	-	-	-	-	-	-
HMCAHBCO_02510	2.1e-116	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HMCAHBCO_02511	1.06e-16	-	-	-	-	-	-	-	-
HMCAHBCO_02512	1.96e-21	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
HMCAHBCO_02513	0.0	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
HMCAHBCO_02514	1.32e-101	nrp	-	-	K	ko:K16509	-	ko00000	ArsC family
HMCAHBCO_02515	7.42e-174	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HMCAHBCO_02516	3.78e-212	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HMCAHBCO_02517	9.62e-19	-	-	-	-	-	-	-	-
HMCAHBCO_02518	1.51e-85	-	-	-	KOT	ko:K07813	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01002	May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
HMCAHBCO_02519	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
HMCAHBCO_02521	8.76e-72	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HMCAHBCO_02522	6.67e-165	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HMCAHBCO_02523	0.0	pox4	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HMCAHBCO_02524	5.03e-95	-	-	-	K	-	-	-	Transcriptional regulator
HMCAHBCO_02525	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HMCAHBCO_02526	6.96e-83	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HMCAHBCO_02527	5.88e-233	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
HMCAHBCO_02528	1.23e-129	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
HMCAHBCO_02529	3.33e-113	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
HMCAHBCO_02530	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HMCAHBCO_02531	1.56e-185	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
HMCAHBCO_02532	2.53e-209	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
HMCAHBCO_02533	2.03e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HMCAHBCO_02534	4.52e-209	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HMCAHBCO_02535	1.88e-240	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HMCAHBCO_02536	3.36e-06	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HMCAHBCO_02537	2.46e-08	-	-	-	-	-	-	-	-
HMCAHBCO_02538	1.23e-26	-	-	-	-	-	-	-	-
HMCAHBCO_02539	1.1e-147	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HMCAHBCO_02540	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HMCAHBCO_02541	9.2e-317	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMCAHBCO_02542	2.09e-85	-	-	-	-	-	-	-	-
HMCAHBCO_02543	2.85e-83	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HMCAHBCO_02544	2.15e-281	-	-	-	S	-	-	-	Membrane
HMCAHBCO_02545	1.04e-59	-	-	-	S	-	-	-	Protein of unknown function (DUF3781)
HMCAHBCO_02546	1.31e-139	yoaZ	-	-	S	-	-	-	intracellular protease amidase
HMCAHBCO_02547	2.33e-56	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HMCAHBCO_02548	5.36e-76	-	-	-	-	-	-	-	-
HMCAHBCO_02549	1.46e-81	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HMCAHBCO_02550	5.31e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
HMCAHBCO_02551	3.17e-258	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HMCAHBCO_02552	2e-62	-	-	-	K	-	-	-	Helix-turn-helix domain
HMCAHBCO_02553	3.87e-115	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HMCAHBCO_02554	1.06e-72	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HMCAHBCO_02555	5.53e-114	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMCAHBCO_02556	6.79e-53	-	-	-	-	-	-	-	-
HMCAHBCO_02557	5.06e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMCAHBCO_02558	1.6e-233	ydbI	-	-	K	-	-	-	AI-2E family transporter
HMCAHBCO_02559	9.28e-271	xylR	-	-	GK	-	-	-	ROK family
HMCAHBCO_02560	2.92e-143	-	-	-	-	-	-	-	-
HMCAHBCO_02561	3.66e-295	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HMCAHBCO_02562	3.32e-210	-	-	-	-	-	-	-	-
HMCAHBCO_02563	1.86e-256	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
HMCAHBCO_02564	9.58e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
HMCAHBCO_02565	2.47e-125	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HMCAHBCO_02566	9.69e-99	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HMCAHBCO_02567	5.61e-39	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HMCAHBCO_02568	1.74e-184	yxeH	-	-	S	-	-	-	hydrolase
HMCAHBCO_02569	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HMCAHBCO_02570	1.68e-146	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HMCAHBCO_02571	1.17e-305	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HMCAHBCO_02572	7.29e-61	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system galactitol-specific IIB component
HMCAHBCO_02573	1.58e-101	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMCAHBCO_02574	0.0	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMCAHBCO_02575	9.14e-146	gph3	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HMCAHBCO_02576	5.26e-247	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
HMCAHBCO_02577	8.37e-296	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HMCAHBCO_02578	6e-60	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HMCAHBCO_02579	3.99e-106	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMCAHBCO_02580	1.83e-146	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
HMCAHBCO_02581	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HMCAHBCO_02582	3.76e-180	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HMCAHBCO_02583	6.47e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HMCAHBCO_02584	8.16e-48	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HMCAHBCO_02585	3.21e-127	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HMCAHBCO_02586	3.89e-205	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HMCAHBCO_02587	0.0	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HMCAHBCO_02588	4.01e-263	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HMCAHBCO_02589	9.03e-173	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HMCAHBCO_02590	1.33e-196	nanK	-	-	GK	-	-	-	ROK family
HMCAHBCO_02591	1.86e-210	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
HMCAHBCO_02592	2.13e-159	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HMCAHBCO_02593	5.6e-292	-	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
HMCAHBCO_02594	1.05e-225	hicD1	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HMCAHBCO_02595	8.95e-60	-	-	-	-	-	-	-	-
HMCAHBCO_02596	1.99e-26	zmp1	-	-	O	-	-	-	Zinc-dependent metalloprotease
HMCAHBCO_02597	8.36e-154	rpiA2	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HMCAHBCO_02598	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
HMCAHBCO_02599	5.34e-72	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HMCAHBCO_02600	1.31e-124	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HMCAHBCO_02601	1.54e-292	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HMCAHBCO_02602	5.89e-108	-	-	-	K	-	-	-	Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HMCAHBCO_02603	2.16e-103	-	-	-	-	-	-	-	-
HMCAHBCO_02604	2.32e-101	accB3	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HMCAHBCO_02605	1.49e-223	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HMCAHBCO_02606	2.42e-207	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HMCAHBCO_02607	4.06e-102	-	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
HMCAHBCO_02608	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HMCAHBCO_02609	2.7e-230	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HMCAHBCO_02610	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HMCAHBCO_02611	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HMCAHBCO_02612	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
HMCAHBCO_02613	2.14e-174	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HMCAHBCO_02614	0.0	-	-	-	M	-	-	-	domain protein
HMCAHBCO_02615	6.75e-85	-	-	-	M	-	-	-	dTDP-4-dehydrorhamnose reductase activity
HMCAHBCO_02616	1.82e-34	-	-	-	S	-	-	-	Immunity protein 74
HMCAHBCO_02617	1.89e-169	-	-	-	S	-	-	-	KR domain
HMCAHBCO_02618	2.56e-83	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HMCAHBCO_02619	1.62e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF1905)
HMCAHBCO_02620	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HMCAHBCO_02621	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HMCAHBCO_02622	2.09e-213	-	-	-	GM	-	-	-	NmrA-like family
HMCAHBCO_02623	1.15e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMCAHBCO_02624	5.93e-281	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HMCAHBCO_02625	6.58e-173	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HMCAHBCO_02626	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HMCAHBCO_02627	7.81e-148	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HMCAHBCO_02628	5.78e-269	-	-	-	EGP	-	-	-	Major Facilitator
HMCAHBCO_02629	3.25e-81	ytcD	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HMCAHBCO_02630	1.06e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HMCAHBCO_02631	4.13e-157	-	-	-	-	-	-	-	-
HMCAHBCO_02632	7.39e-300	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HMCAHBCO_02633	1.47e-83	-	-	-	-	-	-	-	-
HMCAHBCO_02634	3.15e-130	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HMCAHBCO_02635	2.16e-241	ynjC	-	-	S	-	-	-	Cell surface protein
HMCAHBCO_02636	2.63e-146	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HMCAHBCO_02637	5.83e-87	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HMCAHBCO_02638	6.57e-226	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
HMCAHBCO_02653	1.08e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HMCAHBCO_02654	2.81e-178	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HMCAHBCO_02655	9.28e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HMCAHBCO_02656	7.12e-170	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HMCAHBCO_02657	1.64e-17	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HMCAHBCO_02658	1.52e-231	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HMCAHBCO_02659	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HMCAHBCO_02660	2.24e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
HMCAHBCO_02661	1.83e-156	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HMCAHBCO_02662	1.29e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HMCAHBCO_02663	6.31e-222	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HMCAHBCO_02664	7.21e-150	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HMCAHBCO_02665	1.6e-246	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HMCAHBCO_02666	2.68e-75	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HMCAHBCO_02667	9.52e-264	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
HMCAHBCO_02668	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMCAHBCO_02669	1.12e-207	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HMCAHBCO_02671	3.59e-301	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HMCAHBCO_02672	2.5e-147	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HMCAHBCO_02673	4.97e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HMCAHBCO_02674	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HMCAHBCO_02675	0.0	acdH	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
HMCAHBCO_02676	8.16e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HMCAHBCO_02678	2.75e-304	xylP1	-	-	G	-	-	-	MFS/sugar transport protein
HMCAHBCO_02679	5.81e-170	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HMCAHBCO_02680	3.48e-40	-	-	-	-	-	-	-	-
HMCAHBCO_02681	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HMCAHBCO_02682	6.4e-54	-	-	-	-	-	-	-	-
HMCAHBCO_02683	7.31e-122	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HMCAHBCO_02684	6.8e-224	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HMCAHBCO_02685	3.08e-81	-	-	-	S	-	-	-	CHY zinc finger
HMCAHBCO_02686	3.51e-281	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HMCAHBCO_02687	1.57e-280	-	-	-	-	-	-	-	-
HMCAHBCO_02688	1.15e-198	tagG	-	-	U	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HMCAHBCO_02689	9.42e-258	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HMCAHBCO_02690	3.93e-59	-	-	-	-	-	-	-	-
HMCAHBCO_02691	4.63e-119	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HMCAHBCO_02692	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
HMCAHBCO_02693	3.5e-307	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HMCAHBCO_02694	4.2e-88	gcsH1	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Glycine cleavage H-protein
HMCAHBCO_02695	4.29e-227	-	-	-	-	-	-	-	-
HMCAHBCO_02696	3.27e-168	-	-	-	-	-	-	-	-
HMCAHBCO_02697	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
HMCAHBCO_02698	3.01e-75	-	-	-	-	-	-	-	-
HMCAHBCO_02699	3.74e-284	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMCAHBCO_02700	9.81e-33	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HMCAHBCO_02701	1.02e-98	-	-	-	K	-	-	-	Transcriptional regulator
HMCAHBCO_02702	9.59e-288	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HMCAHBCO_02703	2.18e-53	-	-	-	-	-	-	-	-
HMCAHBCO_02704	3.07e-264	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMCAHBCO_02705	1.31e-179	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HMCAHBCO_02706	6.34e-190	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HMCAHBCO_02707	8.8e-264	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HMCAHBCO_02708	3.68e-125	-	-	-	K	-	-	-	Cupin domain
HMCAHBCO_02709	8.08e-110	-	-	-	S	-	-	-	ASCH
HMCAHBCO_02710	1.88e-111	-	-	-	K	-	-	-	GNAT family
HMCAHBCO_02711	2.14e-117	-	-	-	K	-	-	-	acetyltransferase
HMCAHBCO_02712	2.06e-30	-	-	-	-	-	-	-	-
HMCAHBCO_02713	5.05e-79	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HMCAHBCO_02714	1.85e-208	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMCAHBCO_02715	1.08e-243	-	-	-	-	-	-	-	-
HMCAHBCO_02716	2.07e-40	-	-	-	-	-	-	-	-
HMCAHBCO_02717	7.92e-140	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HMCAHBCO_02718	5.93e-73	-	-	-	S	-	-	-	branched-chain amino acid
HMCAHBCO_02719	2.05e-167	-	-	-	E	-	-	-	branched-chain amino acid
HMCAHBCO_02720	1.6e-114	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HMCAHBCO_02721	3.1e-304	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HMCAHBCO_02722	5.61e-273	hpk31	-	-	T	-	-	-	Histidine kinase
HMCAHBCO_02723	1.14e-159	vanR	-	-	K	-	-	-	response regulator
HMCAHBCO_02724	2.4e-161	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HMCAHBCO_02725	3.3e-208	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HMCAHBCO_02726	1.42e-269	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HMCAHBCO_02727	3.49e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HMCAHBCO_02728	6.6e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HMCAHBCO_02729	1.4e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HMCAHBCO_02730	7.16e-201	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HMCAHBCO_02731	1.01e-175	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HMCAHBCO_02732	8.63e-191	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HMCAHBCO_02733	1.81e-168	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HMCAHBCO_02734	4.76e-288	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
HMCAHBCO_02735	2.87e-270	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HMCAHBCO_02736	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HMCAHBCO_02737	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HMCAHBCO_02738	1.25e-86	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HMCAHBCO_02739	6.46e-221	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
HMCAHBCO_02740	1.04e-98	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HMCAHBCO_02742	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HMCAHBCO_02743	1.53e-26	-	-	-	-	-	-	-	-
HMCAHBCO_02744	4.95e-103	-	-	-	-	-	-	-	-
HMCAHBCO_02746	1.32e-224	-	-	-	M	-	-	-	Peptidase family S41
HMCAHBCO_02747	7.34e-124	-	-	-	K	-	-	-	Helix-turn-helix domain
HMCAHBCO_02748	5.05e-05	-	-	-	S	-	-	-	FRG
HMCAHBCO_02749	6.34e-39	-	-	-	-	-	-	-	-
HMCAHBCO_02750	1.4e-13	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HMCAHBCO_02751	7.1e-81	-	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HMCAHBCO_02752	9.04e-78	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
HMCAHBCO_02753	1.11e-59	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HMCAHBCO_02754	1.26e-137	-	-	-	L	-	-	-	Integrase
HMCAHBCO_02755	2.08e-60	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
HMCAHBCO_02756	3.03e-49	-	-	-	K	-	-	-	sequence-specific DNA binding
HMCAHBCO_02757	9.13e-70	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
HMCAHBCO_02758	2.78e-231	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
HMCAHBCO_02759	1.98e-72	repA	-	-	S	-	-	-	Replication initiator protein A
HMCAHBCO_02760	1.32e-57	-	-	-	-	-	-	-	-
HMCAHBCO_02761	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HMCAHBCO_02763	3.53e-38	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMCAHBCO_02764	1.92e-18	mpr	-	-	E	-	-	-	Trypsin-like serine protease
HMCAHBCO_02766	0.0	-	-	-	S	-	-	-	MucBP domain
HMCAHBCO_02767	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HMCAHBCO_02768	4.33e-205	-	-	-	K	-	-	-	LysR substrate binding domain
HMCAHBCO_02769	1.85e-201	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
HMCAHBCO_02770	0.0	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HMCAHBCO_02771	0.0	lepA2	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HMCAHBCO_02772	6.88e-152	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMCAHBCO_02773	7.19e-89	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HMCAHBCO_02774	9.45e-299	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HMCAHBCO_02775	3.74e-302	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMCAHBCO_02776	2.83e-206	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HMCAHBCO_02777	2.91e-190	malA	-	-	S	-	-	-	maltodextrose utilization protein MalA
HMCAHBCO_02778	0.0	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
HMCAHBCO_02779	2.44e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HMCAHBCO_02780	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HMCAHBCO_02781	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
HMCAHBCO_02782	3.26e-102	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HMCAHBCO_02783	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HMCAHBCO_02784	2.66e-132	-	-	-	G	-	-	-	Glycogen debranching enzyme
HMCAHBCO_02785	5.6e-14	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HMCAHBCO_02786	6.72e-208	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HMCAHBCO_02787	2.02e-192	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
HMCAHBCO_02788	1.04e-94	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HMCAHBCO_02789	1.1e-93	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HMCAHBCO_02790	5.74e-32	-	-	-	-	-	-	-	-
HMCAHBCO_02791	1.37e-116	-	-	-	-	-	-	-	-
HMCAHBCO_02792	1.81e-50	ydaS	-	-	S	-	-	-	Transglycosylase associated protein
HMCAHBCO_02793	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase family
HMCAHBCO_02794	1.71e-59	-	-	-	S	-	-	-	MORN repeat
HMCAHBCO_02795	3.39e-52	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HMCAHBCO_02796	5.3e-157	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HMCAHBCO_02797	4.29e-101	-	-	-	-	-	-	-	-
HMCAHBCO_02798	5.09e-51	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HMCAHBCO_02799	2.42e-127	-	-	-	FG	-	-	-	HIT domain
HMCAHBCO_02800	4.27e-223	ydhF	-	-	S	-	-	-	Aldo keto reductase
HMCAHBCO_02801	5.17e-70	-	-	-	S	-	-	-	Pfam:DUF59
HMCAHBCO_02802	4.56e-206	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMCAHBCO_02803	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HMCAHBCO_02804	1.87e-249	-	-	-	V	-	-	-	Beta-lactamase
HMCAHBCO_02805	3.74e-125	-	-	-	V	-	-	-	VanZ like family
HMCAHBCO_02806	6.02e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HMCAHBCO_02807	7.81e-241	-	-	-	S	-	-	-	Cell surface protein
HMCAHBCO_02808	3.15e-98	-	-	-	-	-	-	-	-
HMCAHBCO_02809	0.0	-	-	-	-	-	-	-	-
HMCAHBCO_02810	3.56e-288	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HMCAHBCO_02811	2.97e-51	-	-	-	S	ko:K07343	-	ko00000	TfoX C-terminal domain
HMCAHBCO_02812	2.81e-181	-	-	-	K	-	-	-	Helix-turn-helix domain
HMCAHBCO_02813	4.31e-179	-	-	-	-	-	-	-	-
HMCAHBCO_02814	2.82e-236	-	-	-	S	-	-	-	DUF218 domain
HMCAHBCO_02815	3.26e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMCAHBCO_02816	9.06e-193	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HMCAHBCO_02817	5.78e-292	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HMCAHBCO_02818	1.96e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HMCAHBCO_02819	5.3e-49	-	-	-	-	-	-	-	-
HMCAHBCO_02820	2.95e-57	-	-	-	S	-	-	-	ankyrin repeats
HMCAHBCO_02821	5.13e-119	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HMCAHBCO_02822	7.59e-64	-	-	-	-	-	-	-	-
HMCAHBCO_02823	6.83e-274	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
HMCAHBCO_02824	8.05e-178	-	-	-	F	-	-	-	NUDIX domain
HMCAHBCO_02825	2.68e-32	-	-	-	-	-	-	-	-
HMCAHBCO_02827	8.51e-209	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HMCAHBCO_02828	1.23e-222	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
HMCAHBCO_02829	3.43e-106	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
HMCAHBCO_02830	2.29e-48	-	-	-	-	-	-	-	-
HMCAHBCO_02831	4.54e-45	-	-	-	-	-	-	-	-
HMCAHBCO_02832	9.39e-277	-	-	-	T	-	-	-	diguanylate cyclase
HMCAHBCO_02834	2.55e-218	-	-	-	EG	-	-	-	EamA-like transporter family
HMCAHBCO_02835	1.06e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HMCAHBCO_02836	2.12e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HMCAHBCO_02837	1.45e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HMCAHBCO_02838	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HMCAHBCO_02839	5.23e-277	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HMCAHBCO_02840	2.51e-200	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HMCAHBCO_02841	6.66e-115	-	-	-	-	-	-	-	-
HMCAHBCO_02842	2.29e-225	-	-	-	L	-	-	-	Initiator Replication protein
HMCAHBCO_02843	3.67e-41	-	-	-	-	-	-	-	-
HMCAHBCO_02844	1.87e-139	-	-	-	L	-	-	-	Integrase
HMCAHBCO_02845	4.17e-55	-	-	-	K	-	-	-	prlF antitoxin for toxin YhaV_toxin
HMCAHBCO_02846	1.03e-77	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HMCAHBCO_02847	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
HMCAHBCO_02849	2.78e-80	-	-	-	M	-	-	-	Cna protein B-type domain
HMCAHBCO_02850	0.0	merA	1.16.1.1	-	C	ko:K00520,ko:K21739	-	ko00000,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HMCAHBCO_02851	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
HMCAHBCO_02852	4.67e-35	-	-	-	-	-	-	-	-
HMCAHBCO_02853	6.04e-43	-	-	-	-	-	-	-	-
HMCAHBCO_02854	1.74e-18	-	-	-	Q	-	-	-	Methyltransferase
HMCAHBCO_02855	8.81e-48	-	-	-	L	-	-	-	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HMCAHBCO_02856	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HMCAHBCO_02857	3.1e-172	repA	-	-	S	-	-	-	Replication initiator protein A
HMCAHBCO_02858	1.95e-25	-	-	-	-	-	-	-	-
HMCAHBCO_02859	6.52e-52	-	-	-	S	-	-	-	protein conserved in bacteria
HMCAHBCO_02860	4.93e-54	-	-	-	-	-	-	-	-
HMCAHBCO_02861	1.39e-36	-	-	-	-	-	-	-	-
HMCAHBCO_02862	9.51e-142	XK27_07075	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HMCAHBCO_02863	1.07e-74	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HMCAHBCO_02864	2.13e-167	-	-	-	L	-	-	-	Helix-turn-helix domain
HMCAHBCO_02865	4.73e-206	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HMCAHBCO_02866	6.16e-298	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
HMCAHBCO_02869	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HMCAHBCO_02870	1.61e-74	mleR	-	-	K	-	-	-	LysR substrate binding domain
HMCAHBCO_02871	3.55e-169	-	-	-	K	-	-	-	LysR family
HMCAHBCO_02872	0.0	-	-	-	C	-	-	-	FMN_bind
HMCAHBCO_02873	2.17e-304	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HMCAHBCO_02874	3.99e-101	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HMCAHBCO_02875	7.43e-130	padR	-	-	K	-	-	-	Virulence activator alpha C-term
HMCAHBCO_02876	2.51e-103	-	-	-	T	-	-	-	Universal stress protein family
HMCAHBCO_02877	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HMCAHBCO_02879	7.39e-83	-	-	-	G	-	-	-	COG0662 Mannose-6-phosphate isomerase
HMCAHBCO_02880	2.85e-57	-	-	-	-	-	-	-	-
HMCAHBCO_02881	2.06e-66	ykoF	-	-	S	-	-	-	YKOF-related Family
HMCAHBCO_02882	5.63e-15	-	-	-	E	-	-	-	glutamine synthetase
HMCAHBCO_02883	9.73e-245	-	-	-	E	-	-	-	glutamine synthetase
HMCAHBCO_02884	3.2e-76	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HMCAHBCO_02885	3.16e-59	-	-	-	T	ko:K07172	-	ko00000,ko02048	Antidote-toxin recognition MazE, bacterial antitoxin
HMCAHBCO_02886	9.24e-140	-	-	-	L	-	-	-	Integrase
HMCAHBCO_02887	3.72e-21	-	-	-	-	-	-	-	-
HMCAHBCO_02888	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HMCAHBCO_02889	5.49e-237	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HMCAHBCO_02890	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HMCAHBCO_02891	1.19e-124	-	-	-	L	-	-	-	Resolvase, N terminal domain
HMCAHBCO_02892	7.8e-75	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
HMCAHBCO_02893	9.57e-315	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HMCAHBCO_02894	2.37e-49	-	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
HMCAHBCO_02896	9.33e-249	-	-	-	U	ko:K07085	-	ko00000	Predicted Permease Membrane Region
HMCAHBCO_02897	5.32e-298	aspD	4.1.1.12	-	E	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	ko00000,ko00001,ko01000	Aminotransferase class I and II
HMCAHBCO_02898	1.48e-81	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMCAHBCO_02899	6.47e-10	-	-	-	P	-	-	-	Cation efflux family
HMCAHBCO_02900	8.86e-35	-	-	-	-	-	-	-	-
HMCAHBCO_02901	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
HMCAHBCO_02902	2.44e-303	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HMCAHBCO_02903	1.89e-71	-	-	-	-	-	-	-	-
HMCAHBCO_02904	4.16e-06	-	-	-	S	-	-	-	Transposase C of IS166 homeodomain
HMCAHBCO_02905	5.03e-75	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
HMCAHBCO_02906	3.9e-34	-	-	-	-	-	-	-	-
HMCAHBCO_02907	2.89e-256	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HMCAHBCO_02908	7.86e-68	-	-	-	L	-	-	-	Transposase IS66 family
HMCAHBCO_02909	8.69e-185	-	-	-	D	-	-	-	AAA domain
HMCAHBCO_02910	4.87e-45	-	-	-	-	-	-	-	-
HMCAHBCO_02913	5.62e-49	kdpE	-	-	KT	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HMCAHBCO_02914	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HMCAHBCO_02915	1.74e-72	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HMCAHBCO_02916	5.17e-70	-	-	-	S	-	-	-	Nitroreductase
HMCAHBCO_02917	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HMCAHBCO_02918	4.21e-174	bgaR	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HMCAHBCO_02919	8.61e-19	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	adenosylhomocysteinase activity
HMCAHBCO_02920	1.62e-150	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HMCAHBCO_02921	3.77e-278	-	-	-	EGP	-	-	-	Major Facilitator
HMCAHBCO_02922	4.31e-196	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HMCAHBCO_02923	1.39e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HMCAHBCO_02924	3.23e-150	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
HMCAHBCO_02925	4.27e-146	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
HMCAHBCO_02926	2.09e-151	-	-	-	-	-	-	-	-
HMCAHBCO_02927	1.16e-84	-	-	-	-	-	-	-	-
HMCAHBCO_02928	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HMCAHBCO_02929	5.41e-89	-	-	-	C	-	-	-	lyase activity
HMCAHBCO_02930	2.64e-233	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HMCAHBCO_02931	3.79e-26	-	-	-	-	-	-	-	-
HMCAHBCO_02932	7.57e-122	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMCAHBCO_02933	3.47e-244	-	1.1.1.219	-	GM	ko:K00091	-	ko00000,ko01000	Male sterility protein
HMCAHBCO_02934	1.27e-129	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HMCAHBCO_02936	5.07e-155	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HMCAHBCO_02937	2.83e-58	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
HMCAHBCO_02938	6.45e-111	-	-	-	-	-	-	-	-
HMCAHBCO_02939	8.5e-55	-	-	-	-	-	-	-	-
HMCAHBCO_02940	1.34e-34	-	-	-	-	-	-	-	-
HMCAHBCO_02941	2.62e-160	-	-	-	S	-	-	-	Phage Mu protein F like protein
HMCAHBCO_02942	3.62e-22	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
HMCAHBCO_02943	9.4e-122	-	-	-	L	-	-	-	4.5 Transposon and IS
HMCAHBCO_02944	1.15e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase
HMCAHBCO_02946	3.11e-17	-	-	-	S	-	-	-	protein with an alpha beta hydrolase fold
HMCAHBCO_02947	6.03e-36	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMCAHBCO_02948	2.03e-31	-	-	-	S	-	-	-	Family of unknown function (DUF5388)
HMCAHBCO_02949	1.18e-184	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
HMCAHBCO_02951	6.13e-127	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
HMCAHBCO_02952	1.18e-192	degV	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HMCAHBCO_02953	1.32e-107	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HMCAHBCO_02954	2.26e-39	-	-	-	L	-	-	-	manually curated
HMCAHBCO_02955	2.67e-75	-	-	-	-	-	-	-	-
HMCAHBCO_02956	2.54e-42	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HMCAHBCO_02957	4.19e-54	-	-	-	-	-	-	-	-
HMCAHBCO_02958	1.18e-194	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HMCAHBCO_02960	1.41e-163	-	-	-	P	-	-	-	integral membrane protein, YkoY family
HMCAHBCO_02962	3.47e-47	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
HMCAHBCO_02963	4.05e-211	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HMCAHBCO_02964	3.55e-76	-	-	-	-	-	-	-	-
HMCAHBCO_02965	2.43e-91	-	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
HMCAHBCO_02966	2.58e-147	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HMCAHBCO_02970	1.98e-40	-	-	-	-	-	-	-	-
HMCAHBCO_02972	3.76e-115	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HMCAHBCO_02973	1.95e-114	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
HMCAHBCO_02974	2.69e-105	-	-	-	L	ko:K07498	-	ko00000	DDE domain
HMCAHBCO_02975	1.99e-40	-	-	-	L	-	-	-	RePlication protein