Read a JSON File

ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
NPEPPOKF_00002	2.16e-208	-	-	-	K	-	-	-	Transcriptional regulator
NPEPPOKF_00003	2.43e-206	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
NPEPPOKF_00004	1.66e-211	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
NPEPPOKF_00005	5.73e-100	-	-	-	K	-	-	-	Winged helix DNA-binding domain
NPEPPOKF_00006	0.0	ycaM	-	-	E	-	-	-	amino acid
NPEPPOKF_00007	2.38e-164	aroC1	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
NPEPPOKF_00008	4.3e-44	-	-	-	-	-	-	-	-
NPEPPOKF_00009	0.0	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
NPEPPOKF_00010	9.78e-187	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
NPEPPOKF_00011	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
NPEPPOKF_00012	4.75e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
NPEPPOKF_00013	0.0	-	-	-	-	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	-
NPEPPOKF_00014	1.54e-131	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
NPEPPOKF_00015	1.96e-224	serA1	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
NPEPPOKF_00016	3.98e-204	-	-	-	EG	-	-	-	EamA-like transporter family
NPEPPOKF_00017	6.86e-232	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NPEPPOKF_00018	5.06e-196	-	-	-	S	-	-	-	hydrolase
NPEPPOKF_00019	7.63e-107	-	-	-	-	-	-	-	-
NPEPPOKF_00020	1.75e-156	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
NPEPPOKF_00021	1.4e-181	epsV	-	-	S	-	-	-	glycosyl transferase family 2
NPEPPOKF_00022	1.23e-166	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
NPEPPOKF_00023	1.86e-64	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NPEPPOKF_00024	6.7e-74	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
NPEPPOKF_00025	0.0	pbg5	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NPEPPOKF_00026	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NPEPPOKF_00027	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
NPEPPOKF_00028	4.29e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
NPEPPOKF_00029	9.24e-231	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
NPEPPOKF_00030	6.09e-152	-	-	-	K	-	-	-	Transcriptional regulator
NPEPPOKF_00031	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NPEPPOKF_00032	7.54e-115	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
NPEPPOKF_00033	2.45e-269	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
NPEPPOKF_00034	3.25e-48	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
NPEPPOKF_00035	5.41e-172	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
NPEPPOKF_00036	2.26e-91	-	-	-	FG	-	-	-	Scavenger mRNA decapping enzyme C-term binding
NPEPPOKF_00037	1.13e-132	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
NPEPPOKF_00038	5.88e-142	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
NPEPPOKF_00039	2.99e-38	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
NPEPPOKF_00040	4.65e-186	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NPEPPOKF_00041	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
NPEPPOKF_00042	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
NPEPPOKF_00044	1.21e-69	-	-	-	-	-	-	-	-
NPEPPOKF_00045	1.52e-151	-	-	-	-	-	-	-	-
NPEPPOKF_00046	1.16e-110	-	-	-	F	-	-	-	belongs to the nudix hydrolase family
NPEPPOKF_00047	3.03e-299	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
NPEPPOKF_00048	4.79e-13	-	-	-	-	-	-	-	-
NPEPPOKF_00049	5.92e-67	-	-	-	-	-	-	-	-
NPEPPOKF_00050	1.76e-114	-	-	-	-	-	-	-	-
NPEPPOKF_00051	5.7e-95	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
NPEPPOKF_00052	3.64e-46	-	-	-	-	-	-	-	-
NPEPPOKF_00053	1.1e-103	usp5	-	-	T	-	-	-	universal stress protein
NPEPPOKF_00054	4.21e-175	-	-	-	-	-	-	-	-
NPEPPOKF_00055	7.89e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPPOKF_00056	8.2e-81	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
NPEPPOKF_00057	1.87e-53	-	-	-	-	-	-	-	-
NPEPPOKF_00058	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NPEPPOKF_00059	2.05e-178	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPPOKF_00060	3.7e-233	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
NPEPPOKF_00061	6.89e-190	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NPEPPOKF_00062	5.95e-153	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
NPEPPOKF_00063	4.81e-188	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
NPEPPOKF_00064	5.76e-243	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
NPEPPOKF_00065	9.92e-143	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
NPEPPOKF_00066	4.57e-304	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
NPEPPOKF_00067	3.77e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NPEPPOKF_00068	2.87e-270	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NPEPPOKF_00069	3.39e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
NPEPPOKF_00070	1.17e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPEPPOKF_00071	6.91e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPEPPOKF_00072	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPEPPOKF_00073	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NPEPPOKF_00074	4.22e-243	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
NPEPPOKF_00075	5.35e-133	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NPEPPOKF_00076	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
NPEPPOKF_00077	9.06e-279	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
NPEPPOKF_00078	1.83e-157	-	-	-	E	-	-	-	Methionine synthase
NPEPPOKF_00079	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
NPEPPOKF_00080	1.85e-121	-	-	-	-	-	-	-	-
NPEPPOKF_00081	1.25e-199	-	-	-	T	-	-	-	EAL domain
NPEPPOKF_00082	2.24e-206	-	-	-	GM	-	-	-	NmrA-like family
NPEPPOKF_00083	5.67e-280	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
NPEPPOKF_00084	3.1e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
NPEPPOKF_00085	0.0	pucR_2	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
NPEPPOKF_00086	7.13e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NPEPPOKF_00087	2.02e-219	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
NPEPPOKF_00088	1.61e-308	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NPEPPOKF_00089	2.76e-271	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
NPEPPOKF_00090	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
NPEPPOKF_00091	1.04e-218	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NPEPPOKF_00092	1.55e-161	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NPEPPOKF_00093	5.46e-145	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NPEPPOKF_00094	1.12e-216	oroP	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
NPEPPOKF_00095	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NPEPPOKF_00096	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
NPEPPOKF_00097	3.86e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
NPEPPOKF_00098	1.29e-148	-	-	-	GM	-	-	-	NAD(P)H-binding
NPEPPOKF_00099	6.68e-207	mleR	-	-	K	-	-	-	LysR family
NPEPPOKF_00100	2.09e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NPEPPOKF_00101	3.59e-26	-	-	-	-	-	-	-	-
NPEPPOKF_00102	1.84e-204	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NPEPPOKF_00103	1.02e-277	araT2	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NPEPPOKF_00104	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	Bacterial regulatory proteins, gntR family
NPEPPOKF_00105	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NPEPPOKF_00106	4.71e-74	-	-	-	S	-	-	-	SdpI/YhfL protein family
NPEPPOKF_00107	4.68e-161	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
NPEPPOKF_00108	9.75e-39	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
NPEPPOKF_00109	3.45e-83	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NPEPPOKF_00110	2.03e-271	yttB	-	-	EGP	-	-	-	Major Facilitator
NPEPPOKF_00111	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
NPEPPOKF_00112	1.18e-114	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
NPEPPOKF_00113	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
NPEPPOKF_00114	2.97e-76	-	-	-	-	-	-	-	-
NPEPPOKF_00115	2.61e-96	hsp2	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
NPEPPOKF_00116	1.55e-79	-	-	-	-	-	-	-	-
NPEPPOKF_00117	1.7e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
NPEPPOKF_00118	8.05e-179	rrp8	-	-	K	-	-	-	LytTr DNA-binding domain
NPEPPOKF_00119	1.97e-150	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NPEPPOKF_00120	2.48e-178	-	-	-	-	-	-	-	-
NPEPPOKF_00121	4.75e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NPEPPOKF_00122	3.53e-169	-	-	-	K	-	-	-	Transcriptional regulator
NPEPPOKF_00123	2.01e-209	-	-	-	S	-	-	-	Putative esterase
NPEPPOKF_00124	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
NPEPPOKF_00125	1.25e-283	-	-	-	M	-	-	-	Glycosyl transferases group 1
NPEPPOKF_00126	1.38e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
NPEPPOKF_00127	4.05e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
NPEPPOKF_00128	2.5e-203	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
NPEPPOKF_00129	2.51e-103	uspA3	-	-	T	-	-	-	universal stress protein
NPEPPOKF_00130	0.0	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
NPEPPOKF_00131	4.26e-250	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
NPEPPOKF_00132	4.15e-78	-	-	-	-	-	-	-	-
NPEPPOKF_00133	1.65e-97	-	-	-	-	-	-	-	-
NPEPPOKF_00134	6.94e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2798)
NPEPPOKF_00135	2.57e-70	-	-	-	-	-	-	-	-
NPEPPOKF_00136	3.89e-62	-	-	-	-	-	-	-	-
NPEPPOKF_00137	3.87e-262	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
NPEPPOKF_00138	9.89e-74	ytpP	-	-	CO	-	-	-	Thioredoxin
NPEPPOKF_00139	1.19e-186	-	-	-	S	ko:K06889	-	ko00000	Dienelactone hydrolase family
NPEPPOKF_00140	1.83e-37	-	-	-	-	-	-	-	-
NPEPPOKF_00141	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
NPEPPOKF_00142	2.8e-63	-	-	-	-	-	-	-	-
NPEPPOKF_00143	1.23e-75	-	-	-	-	-	-	-	-
NPEPPOKF_00144	1.86e-210	-	-	-	-	-	-	-	-
NPEPPOKF_00145	1.4e-95	-	-	-	K	-	-	-	Transcriptional regulator
NPEPPOKF_00146	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
NPEPPOKF_00147	8.94e-221	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
NPEPPOKF_00148	7.2e-61	-	-	-	S	-	-	-	Enterocin A Immunity
NPEPPOKF_00149	8.34e-86	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
NPEPPOKF_00150	1.01e-161	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NPEPPOKF_00151	2.66e-172	-	-	-	-	-	-	-	-
NPEPPOKF_00152	9.38e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
NPEPPOKF_00153	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NPEPPOKF_00154	0.0	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
NPEPPOKF_00155	8.97e-253	yhhX	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
NPEPPOKF_00156	2.48e-227	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
NPEPPOKF_00157	5.91e-150	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
NPEPPOKF_00158	1.48e-201	ccpB	-	-	K	-	-	-	lacI family
NPEPPOKF_00159	2.2e-157	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NPEPPOKF_00160	3.68e-203	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NPEPPOKF_00161	5.02e-228	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
NPEPPOKF_00162	3e-127	-	-	-	C	-	-	-	Nitroreductase family
NPEPPOKF_00163	6.04e-217	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
NPEPPOKF_00164	2.14e-183	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NPEPPOKF_00165	2.71e-234	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
NPEPPOKF_00166	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
NPEPPOKF_00167	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NPEPPOKF_00168	6.05e-98	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
NPEPPOKF_00169	1.78e-279	-	-	-	M	-	-	-	domain protein
NPEPPOKF_00170	6.32e-67	-	-	-	M	-	-	-	domain protein
NPEPPOKF_00171	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
NPEPPOKF_00172	1.06e-145	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
NPEPPOKF_00173	1.45e-46	-	-	-	-	-	-	-	-
NPEPPOKF_00174	5.48e-236	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NPEPPOKF_00175	1.97e-254	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NPEPPOKF_00176	4.54e-126	-	-	-	J	-	-	-	glyoxalase III activity
NPEPPOKF_00177	1.01e-189	-	-	-	GM	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
NPEPPOKF_00178	4.73e-118	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
NPEPPOKF_00179	6.7e-74	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
NPEPPOKF_00180	7.28e-213	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
NPEPPOKF_00181	3.72e-283	ysaA	-	-	V	-	-	-	RDD family
NPEPPOKF_00182	4.54e-208	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
NPEPPOKF_00183	2.3e-275	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NPEPPOKF_00184	1.69e-151	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NPEPPOKF_00185	7.8e-299	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NPEPPOKF_00186	2.46e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
NPEPPOKF_00187	2.23e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NPEPPOKF_00188	5.62e-165	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NPEPPOKF_00189	1.27e-172	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NPEPPOKF_00190	6.12e-78	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NPEPPOKF_00191	1.07e-68	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
NPEPPOKF_00192	1.9e-258	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NPEPPOKF_00193	2.47e-125	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
NPEPPOKF_00194	1.18e-175	yceF	-	-	P	ko:K05794	-	ko00000	membrane
NPEPPOKF_00195	9.51e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
NPEPPOKF_00196	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
NPEPPOKF_00197	1.32e-178	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPPOKF_00198	6.03e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NPEPPOKF_00199	9.31e-225	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
NPEPPOKF_00200	1.53e-213	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
NPEPPOKF_00201	6.08e-312	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
NPEPPOKF_00202	6.83e-292	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
NPEPPOKF_00203	3.45e-209	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
NPEPPOKF_00204	1.31e-242	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NPEPPOKF_00205	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
NPEPPOKF_00206	2.64e-61	-	-	-	-	-	-	-	-
NPEPPOKF_00207	2.35e-106	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPEPPOKF_00208	9.24e-140	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
NPEPPOKF_00209	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
NPEPPOKF_00210	7.17e-62	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NPEPPOKF_00211	2.15e-07	-	-	-	K	-	-	-	transcriptional regulator
NPEPPOKF_00212	5.58e-274	-	-	-	S	-	-	-	membrane
NPEPPOKF_00213	1.51e-105	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NPEPPOKF_00214	0.0	-	-	-	S	-	-	-	Zinc finger, swim domain protein
NPEPPOKF_00215	8.09e-146	-	-	-	GM	-	-	-	epimerase
NPEPPOKF_00216	6.34e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
NPEPPOKF_00217	2.65e-93	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
NPEPPOKF_00218	1.4e-137	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
NPEPPOKF_00219	1.68e-176	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
NPEPPOKF_00220	0.0	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NPEPPOKF_00221	1.3e-264	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
NPEPPOKF_00222	4.38e-102	-	-	-	K	-	-	-	Transcriptional regulator
NPEPPOKF_00223	4.6e-307	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
NPEPPOKF_00224	1.27e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NPEPPOKF_00225	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
NPEPPOKF_00226	1.68e-229	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
NPEPPOKF_00227	4.8e-278	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
NPEPPOKF_00228	1.93e-266	-	-	-	-	-	-	-	-
NPEPPOKF_00229	6.11e-118	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NPEPPOKF_00230	2.65e-81	-	-	-	P	-	-	-	Rhodanese Homology Domain
NPEPPOKF_00231	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
NPEPPOKF_00232	2.74e-112	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NPEPPOKF_00233	2.08e-213	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NPEPPOKF_00234	2.52e-165	drrB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
NPEPPOKF_00235	1.75e-295	-	-	-	M	-	-	-	O-Antigen ligase
NPEPPOKF_00236	6.85e-164	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
NPEPPOKF_00237	1.09e-249	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NPEPPOKF_00238	1.29e-298	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
NPEPPOKF_00239	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NPEPPOKF_00241	7.03e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
NPEPPOKF_00242	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
NPEPPOKF_00243	8.69e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NPEPPOKF_00244	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
NPEPPOKF_00245	2.51e-98	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
NPEPPOKF_00246	4.59e-217	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
NPEPPOKF_00247	3.13e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
NPEPPOKF_00248	3.99e-92	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPEPPOKF_00249	7.1e-176	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NPEPPOKF_00250	1.3e-132	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NPEPPOKF_00251	2.69e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NPEPPOKF_00252	2.24e-126	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NPEPPOKF_00253	3.38e-252	-	-	-	S	-	-	-	Helix-turn-helix domain
NPEPPOKF_00254	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
NPEPPOKF_00255	1.25e-39	-	-	-	M	-	-	-	Lysin motif
NPEPPOKF_00256	1.27e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
NPEPPOKF_00257	1.98e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
NPEPPOKF_00258	5.89e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
NPEPPOKF_00259	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NPEPPOKF_00260	2.08e-284	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
NPEPPOKF_00261	1.29e-192	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
NPEPPOKF_00262	1.39e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NPEPPOKF_00263	6.04e-290	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NPEPPOKF_00264	6.46e-109	-	-	-	-	-	-	-	-
NPEPPOKF_00265	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NPEPPOKF_00266	6.7e-241	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NPEPPOKF_00267	1.8e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NPEPPOKF_00268	2.03e-189	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
NPEPPOKF_00269	1.19e-208	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NPEPPOKF_00270	3.29e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
NPEPPOKF_00271	9.33e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
NPEPPOKF_00272	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
NPEPPOKF_00273	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
NPEPPOKF_00274	4.28e-253	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
NPEPPOKF_00275	3.53e-160	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
NPEPPOKF_00276	1.27e-222	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
NPEPPOKF_00277	1.73e-219	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
NPEPPOKF_00278	5.99e-291	XK27_05470	-	-	E	-	-	-	Methionine synthase
NPEPPOKF_00280	2.25e-207	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NPEPPOKF_00281	8.64e-177	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NPEPPOKF_00282	2.33e-202	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
NPEPPOKF_00283	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NPEPPOKF_00284	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NPEPPOKF_00285	1.5e-227	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
NPEPPOKF_00286	6.84e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NPEPPOKF_00287	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NPEPPOKF_00288	3.64e-217	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
NPEPPOKF_00289	2.4e-137	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NPEPPOKF_00290	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NPEPPOKF_00291	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NPEPPOKF_00292	2.21e-227	-	-	-	K	-	-	-	Transcriptional regulator
NPEPPOKF_00293	3.21e-215	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
NPEPPOKF_00294	3.8e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
NPEPPOKF_00295	9.17e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NPEPPOKF_00296	1.07e-43	-	-	-	S	-	-	-	YozE SAM-like fold
NPEPPOKF_00297	3.59e-204	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
NPEPPOKF_00298	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NPEPPOKF_00299	4.49e-315	-	-	-	M	-	-	-	Glycosyl transferase family group 2
NPEPPOKF_00300	3.22e-87	-	-	-	-	-	-	-	-
NPEPPOKF_00301	0.0	gshR1	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
NPEPPOKF_00302	1.48e-98	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NPEPPOKF_00303	4.87e-123	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
NPEPPOKF_00304	0.0	tarL	2.7.8.14, 2.7.8.47	-	H	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NPEPPOKF_00305	1.43e-273	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	H	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NPEPPOKF_00306	6.51e-247	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
NPEPPOKF_00307	2.13e-151	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
NPEPPOKF_00308	4.76e-290	-	-	-	-	-	-	-	-
NPEPPOKF_00309	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
NPEPPOKF_00310	7.79e-78	-	-	-	-	-	-	-	-
NPEPPOKF_00311	2.79e-181	-	-	-	-	-	-	-	-
NPEPPOKF_00312	1.06e-312	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
NPEPPOKF_00313	1.05e-176	XK27_00890	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
NPEPPOKF_00314	9.3e-167	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
NPEPPOKF_00315	1.33e-67	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
NPEPPOKF_00317	6e-268	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
NPEPPOKF_00318	4.87e-191	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
NPEPPOKF_00319	2.37e-65	-	-	-	-	-	-	-	-
NPEPPOKF_00320	1.27e-35	-	-	-	-	-	-	-	-
NPEPPOKF_00321	1.96e-168	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
NPEPPOKF_00322	2.47e-101	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
NPEPPOKF_00323	4.53e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
NPEPPOKF_00324	1.97e-87	-	-	-	K	-	-	-	Transcriptional regulator
NPEPPOKF_00325	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
NPEPPOKF_00326	1.6e-171	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NPEPPOKF_00327	2.16e-208	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPPOKF_00328	1.37e-119	-	-	-	F	-	-	-	NUDIX domain
NPEPPOKF_00329	1.19e-176	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
NPEPPOKF_00330	2.08e-92	-	-	-	S	-	-	-	LuxR family transcriptional regulator
NPEPPOKF_00331	1.92e-168	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
NPEPPOKF_00334	1.9e-93	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
NPEPPOKF_00335	3.34e-144	-	-	-	G	-	-	-	Phosphoglycerate mutase family
NPEPPOKF_00336	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
NPEPPOKF_00337	4.89e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
NPEPPOKF_00338	1.9e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NPEPPOKF_00339	9.72e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NPEPPOKF_00340	1.65e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NPEPPOKF_00341	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
NPEPPOKF_00342	5.89e-81	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
NPEPPOKF_00343	3.28e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
NPEPPOKF_00344	2.44e-267	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
NPEPPOKF_00345	2.13e-186	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
NPEPPOKF_00346	2.27e-247	-	-	-	-	-	-	-	-
NPEPPOKF_00347	1.9e-156	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NPEPPOKF_00348	4.35e-159	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
NPEPPOKF_00349	1.38e-232	-	-	-	V	-	-	-	LD-carboxypeptidase
NPEPPOKF_00350	1.23e-311	-	-	-	M	ko:K07273	-	ko00000	hydrolase, family 25
NPEPPOKF_00351	3.2e-70	-	-	-	-	-	-	-	-
NPEPPOKF_00352	3.15e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NPEPPOKF_00353	1.57e-179	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
NPEPPOKF_00354	6.42e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NPEPPOKF_00355	9.99e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
NPEPPOKF_00356	1.6e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
NPEPPOKF_00357	7.69e-300	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NPEPPOKF_00358	1.46e-77	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NPEPPOKF_00359	2.85e-293	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NPEPPOKF_00360	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
NPEPPOKF_00361	4.49e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NPEPPOKF_00362	3.33e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NPEPPOKF_00363	2.17e-244	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NPEPPOKF_00364	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NPEPPOKF_00365	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
NPEPPOKF_00366	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
NPEPPOKF_00367	1.61e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
NPEPPOKF_00368	1.84e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
NPEPPOKF_00369	3.16e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
NPEPPOKF_00370	1.21e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NPEPPOKF_00371	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
NPEPPOKF_00372	1.62e-173	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
NPEPPOKF_00373	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NPEPPOKF_00374	1.01e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NPEPPOKF_00375	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NPEPPOKF_00376	1.28e-276	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NPEPPOKF_00377	3.93e-41	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NPEPPOKF_00378	6.96e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
NPEPPOKF_00379	8.28e-73	-	-	-	-	-	-	-	-
NPEPPOKF_00380	1.36e-136	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NPEPPOKF_00381	3.8e-224	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NPEPPOKF_00382	7.11e-135	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NPEPPOKF_00383	4.51e-284	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPPOKF_00384	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
NPEPPOKF_00385	2.15e-99	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NPEPPOKF_00386	4.49e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
NPEPPOKF_00387	7.16e-201	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NPEPPOKF_00388	7.55e-44	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NPEPPOKF_00389	3.28e-312	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NPEPPOKF_00390	4.82e-194	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NPEPPOKF_00391	2.82e-91	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NPEPPOKF_00392	1.7e-96	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
NPEPPOKF_00393	1.43e-129	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NPEPPOKF_00394	4.08e-247	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
NPEPPOKF_00395	2.33e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
NPEPPOKF_00396	7.97e-71	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
NPEPPOKF_00397	1.55e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
NPEPPOKF_00398	8.15e-125	-	-	-	K	-	-	-	Transcriptional regulator
NPEPPOKF_00399	9.81e-27	-	-	-	-	-	-	-	-
NPEPPOKF_00402	2.97e-41	-	-	-	-	-	-	-	-
NPEPPOKF_00403	3.11e-73	-	-	-	-	-	-	-	-
NPEPPOKF_00404	2.92e-126	-	-	-	S	-	-	-	Protein conserved in bacteria
NPEPPOKF_00405	1.34e-232	-	-	-	-	-	-	-	-
NPEPPOKF_00406	1.18e-205	-	-	-	-	-	-	-	-
NPEPPOKF_00407	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
NPEPPOKF_00408	7.79e-85	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
NPEPPOKF_00409	3.8e-224	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NPEPPOKF_00410	7.77e-179	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
NPEPPOKF_00411	1.44e-31	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
NPEPPOKF_00412	1.15e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
NPEPPOKF_00413	1.62e-141	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
NPEPPOKF_00414	2.6e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
NPEPPOKF_00415	6.33e-46	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
NPEPPOKF_00416	3.52e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
NPEPPOKF_00417	9.29e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NPEPPOKF_00418	5.33e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
NPEPPOKF_00419	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
NPEPPOKF_00420	0.0	-	-	-	S	-	-	-	membrane
NPEPPOKF_00421	6.12e-72	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
NPEPPOKF_00422	5.72e-99	-	-	-	K	-	-	-	LytTr DNA-binding domain
NPEPPOKF_00423	9.72e-146	-	-	-	S	-	-	-	membrane
NPEPPOKF_00424	1.09e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NPEPPOKF_00425	7.5e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
NPEPPOKF_00426	6.11e-249	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NPEPPOKF_00427	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NPEPPOKF_00428	6.88e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NPEPPOKF_00429	2.58e-82	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NPEPPOKF_00430	1.72e-120	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NPEPPOKF_00431	4.46e-179	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NPEPPOKF_00432	1.37e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
NPEPPOKF_00433	6.94e-209	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NPEPPOKF_00434	4.18e-121	-	-	-	S	-	-	-	SdpI/YhfL protein family
NPEPPOKF_00435	1.36e-288	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NPEPPOKF_00436	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
NPEPPOKF_00437	1.93e-218	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
NPEPPOKF_00438	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NPEPPOKF_00439	1.38e-155	csrR	-	-	K	-	-	-	response regulator
NPEPPOKF_00440	2.56e-310	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
NPEPPOKF_00441	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NPEPPOKF_00442	1.09e-223	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NPEPPOKF_00443	3.06e-124	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
NPEPPOKF_00444	3.66e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
NPEPPOKF_00445	3.04e-280	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
NPEPPOKF_00446	3.3e-180	yqeM	-	-	Q	-	-	-	Methyltransferase
NPEPPOKF_00447	1.06e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NPEPPOKF_00448	1.71e-149	yqeK	-	-	H	-	-	-	Hydrolase, HD family
NPEPPOKF_00449	4.19e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NPEPPOKF_00450	2.19e-67	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
NPEPPOKF_00451	3.81e-276	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
NPEPPOKF_00452	5.7e-127	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
NPEPPOKF_00453	6.32e-114	-	-	-	-	-	-	-	-
NPEPPOKF_00454	3.83e-100	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
NPEPPOKF_00455	3.97e-174	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
NPEPPOKF_00456	1.64e-83	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NPEPPOKF_00457	1.18e-250	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NPEPPOKF_00458	7.03e-307	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
NPEPPOKF_00459	4.59e-73	-	-	-	-	-	-	-	-
NPEPPOKF_00460	6.88e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NPEPPOKF_00461	6.92e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
NPEPPOKF_00462	2.37e-109	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NPEPPOKF_00463	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NPEPPOKF_00464	3.5e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
NPEPPOKF_00465	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
NPEPPOKF_00466	1.58e-117	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NPEPPOKF_00467	1.92e-133	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NPEPPOKF_00468	3.19e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NPEPPOKF_00469	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NPEPPOKF_00470	8.51e-155	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
NPEPPOKF_00471	1.04e-141	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
NPEPPOKF_00472	4.07e-60	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
NPEPPOKF_00473	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
NPEPPOKF_00474	2.71e-108	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
NPEPPOKF_00475	1.11e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NPEPPOKF_00476	5.21e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
NPEPPOKF_00477	1.1e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
NPEPPOKF_00478	2.87e-47	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
NPEPPOKF_00479	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
NPEPPOKF_00480	3.04e-29	-	-	-	S	-	-	-	Virus attachment protein p12 family
NPEPPOKF_00481	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
NPEPPOKF_00482	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
NPEPPOKF_00483	1.29e-148	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NPEPPOKF_00484	2.94e-71	ytzB	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
NPEPPOKF_00485	2.8e-155	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NPEPPOKF_00486	7.24e-197	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
NPEPPOKF_00487	8.17e-285	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
NPEPPOKF_00488	1.1e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPPOKF_00489	3.6e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
NPEPPOKF_00490	6.76e-73	-	-	-	-	-	-	-	-
NPEPPOKF_00491	1.09e-196	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NPEPPOKF_00492	1.78e-153	draG	-	-	O	-	-	-	ADP-ribosylglycohydrolase
NPEPPOKF_00493	5.76e-135	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
NPEPPOKF_00494	2.82e-138	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
NPEPPOKF_00495	1.94e-247	-	-	-	S	-	-	-	Fn3-like domain
NPEPPOKF_00496	1.65e-80	-	-	-	-	-	-	-	-
NPEPPOKF_00497	0.0	-	-	-	-	-	-	-	-
NPEPPOKF_00498	4.26e-308	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
NPEPPOKF_00499	3.22e-147	zmp2	-	-	O	-	-	-	Zinc-dependent metalloprotease
NPEPPOKF_00500	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
NPEPPOKF_00501	1.62e-158	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NPEPPOKF_00502	5.96e-69	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
NPEPPOKF_00503	9.43e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
NPEPPOKF_00504	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NPEPPOKF_00505	4.91e-265	yacL	-	-	S	-	-	-	domain protein
NPEPPOKF_00506	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NPEPPOKF_00507	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NPEPPOKF_00508	1.35e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NPEPPOKF_00509	1.49e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NPEPPOKF_00510	1.44e-125	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
NPEPPOKF_00511	1.12e-130	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
NPEPPOKF_00512	4.55e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
NPEPPOKF_00513	1e-39	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NPEPPOKF_00514	1.89e-128	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
NPEPPOKF_00515	2.81e-202	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NPEPPOKF_00516	9.76e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NPEPPOKF_00517	2.69e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NPEPPOKF_00518	3.72e-105	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NPEPPOKF_00519	2.76e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NPEPPOKF_00520	1.01e-226	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
NPEPPOKF_00521	4.82e-86	-	-	-	L	-	-	-	nuclease
NPEPPOKF_00522	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NPEPPOKF_00523	2.37e-140	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
NPEPPOKF_00524	2.47e-253	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPEPPOKF_00525	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPEPPOKF_00526	8.42e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
NPEPPOKF_00527	6.7e-141	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
NPEPPOKF_00528	7.57e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NPEPPOKF_00529	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NPEPPOKF_00530	8.34e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NPEPPOKF_00531	6.22e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NPEPPOKF_00532	1.01e-51	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
NPEPPOKF_00533	1.82e-152	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NPEPPOKF_00534	1.39e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
NPEPPOKF_00535	2.33e-239	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NPEPPOKF_00536	8.46e-77	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
NPEPPOKF_00537	2.64e-213	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NPEPPOKF_00538	1.29e-190	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
NPEPPOKF_00539	4.95e-246	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
NPEPPOKF_00540	5.35e-270	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
NPEPPOKF_00541	2.8e-187	phnX	3.11.1.1	-	E	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the HAD-like hydrolase superfamily. PhnX family
NPEPPOKF_00542	3.33e-184	phnE1	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NPEPPOKF_00543	2.18e-176	phnE2	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter permease
NPEPPOKF_00544	3.8e-176	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NPEPPOKF_00545	3.46e-242	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
NPEPPOKF_00546	6.84e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
NPEPPOKF_00547	4.66e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
NPEPPOKF_00548	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NPEPPOKF_00549	3.62e-249	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NPEPPOKF_00550	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
NPEPPOKF_00551	3.67e-154	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NPEPPOKF_00552	2.38e-140	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NPEPPOKF_00553	9.82e-55	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NPEPPOKF_00554	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NPEPPOKF_00555	0.0	ydaO	-	-	E	-	-	-	amino acid
NPEPPOKF_00556	7.29e-247	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
NPEPPOKF_00557	6.57e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
NPEPPOKF_00558	3.7e-149	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
NPEPPOKF_00559	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
NPEPPOKF_00560	2.94e-164	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
NPEPPOKF_00561	1.27e-129	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NPEPPOKF_00562	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NPEPPOKF_00563	3.41e-257	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NPEPPOKF_00564	1.05e-275	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
NPEPPOKF_00565	1.49e-170	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
NPEPPOKF_00566	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NPEPPOKF_00567	2.31e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
NPEPPOKF_00568	9.05e-206	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
NPEPPOKF_00569	5.04e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
NPEPPOKF_00570	9.78e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NPEPPOKF_00571	4.47e-177	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NPEPPOKF_00572	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
NPEPPOKF_00573	2.78e-65	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
NPEPPOKF_00574	2.87e-71	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
NPEPPOKF_00575	2.55e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NPEPPOKF_00576	6.26e-213	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NPEPPOKF_00577	4e-235	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
NPEPPOKF_00578	1.13e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
NPEPPOKF_00579	6.37e-160	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
NPEPPOKF_00580	0.0	nox	-	-	C	-	-	-	NADH oxidase
NPEPPOKF_00581	8.65e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NPEPPOKF_00582	4.31e-141	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
NPEPPOKF_00583	7.54e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
NPEPPOKF_00584	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NPEPPOKF_00585	5.9e-170	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
NPEPPOKF_00586	0.0	nox2	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NPEPPOKF_00587	1.89e-134	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NPEPPOKF_00588	5.33e-268	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
NPEPPOKF_00589	3.85e-151	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
NPEPPOKF_00590	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NPEPPOKF_00591	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NPEPPOKF_00592	2.21e-113	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NPEPPOKF_00593	7.5e-302	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
NPEPPOKF_00594	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
NPEPPOKF_00595	3.51e-113	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
NPEPPOKF_00596	1.71e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
NPEPPOKF_00597	5.32e-242	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
NPEPPOKF_00598	1.21e-215	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
NPEPPOKF_00599	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
NPEPPOKF_00600	8.58e-223	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPEPPOKF_00601	5.11e-133	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NPEPPOKF_00603	1.14e-311	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
NPEPPOKF_00604	5.75e-242	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
NPEPPOKF_00605	2.02e-245	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NPEPPOKF_00606	1.31e-285	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
NPEPPOKF_00607	7.15e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NPEPPOKF_00608	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NPEPPOKF_00609	2.83e-168	-	-	-	-	-	-	-	-
NPEPPOKF_00610	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
NPEPPOKF_00611	3.55e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
NPEPPOKF_00612	3.83e-179	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
NPEPPOKF_00613	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NPEPPOKF_00614	2.4e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NPEPPOKF_00615	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
NPEPPOKF_00616	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NPEPPOKF_00617	9.36e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NPEPPOKF_00618	7.98e-137	-	-	-	-	-	-	-	-
NPEPPOKF_00619	1.98e-199	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NPEPPOKF_00620	1.4e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NPEPPOKF_00621	1.23e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
NPEPPOKF_00622	1.29e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
NPEPPOKF_00623	2.52e-114	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NPEPPOKF_00624	2.41e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NPEPPOKF_00625	2.53e-198	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
NPEPPOKF_00626	3.09e-213	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
NPEPPOKF_00627	6.24e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
NPEPPOKF_00628	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
NPEPPOKF_00629	3.07e-119	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NPEPPOKF_00630	8.06e-156	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
NPEPPOKF_00631	2.39e-191	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NPEPPOKF_00632	2.18e-182	ybbR	-	-	S	-	-	-	YbbR-like protein
NPEPPOKF_00633	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NPEPPOKF_00634	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NPEPPOKF_00635	2e-98	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	general stress protein
NPEPPOKF_00636	5.16e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NPEPPOKF_00637	8.38e-152	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
NPEPPOKF_00638	2.71e-150	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
NPEPPOKF_00639	7.18e-189	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NPEPPOKF_00640	1.96e-116	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
NPEPPOKF_00641	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
NPEPPOKF_00642	5.77e-151	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NPEPPOKF_00643	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
NPEPPOKF_00644	4.7e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NPEPPOKF_00645	3.68e-235	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
NPEPPOKF_00647	6.46e-113	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
NPEPPOKF_00648	3.03e-27	-	-	-	-	ko:K02671	-	ko00000,ko02035,ko02044	-
NPEPPOKF_00649	1.5e-108	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
NPEPPOKF_00650	1.97e-72	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
NPEPPOKF_00651	6.2e-242	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
NPEPPOKF_00652	2.57e-224	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
NPEPPOKF_00653	2.06e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NPEPPOKF_00654	2.21e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
NPEPPOKF_00655	2.44e-65	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
NPEPPOKF_00656	3.21e-210	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
NPEPPOKF_00657	5.44e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
NPEPPOKF_00658	7.36e-274	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
NPEPPOKF_00659	9.86e-82	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NPEPPOKF_00660	1.6e-96	-	-	-	-	-	-	-	-
NPEPPOKF_00661	1.88e-75	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NPEPPOKF_00662	2.31e-202	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
NPEPPOKF_00663	6.72e-289	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NPEPPOKF_00664	2.29e-112	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NPEPPOKF_00665	7.94e-114	ykuL	-	-	S	-	-	-	(CBS) domain
NPEPPOKF_00666	4.03e-125	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
NPEPPOKF_00667	8.49e-144	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NPEPPOKF_00668	5.06e-194	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
NPEPPOKF_00669	1.45e-161	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
NPEPPOKF_00670	3e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
NPEPPOKF_00671	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NPEPPOKF_00672	1.06e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NPEPPOKF_00673	1.31e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
NPEPPOKF_00674	5.39e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NPEPPOKF_00675	5e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
NPEPPOKF_00676	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NPEPPOKF_00677	2.79e-316	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NPEPPOKF_00678	8.32e-227	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
NPEPPOKF_00679	2.48e-276	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NPEPPOKF_00680	1.32e-63	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
NPEPPOKF_00681	9.91e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NPEPPOKF_00682	5.87e-256	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NPEPPOKF_00683	2.62e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NPEPPOKF_00684	2.83e-138	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NPEPPOKF_00685	4.02e-114	-	-	-	-	-	-	-	-
NPEPPOKF_00686	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
NPEPPOKF_00687	1.3e-91	-	-	-	-	-	-	-	-
NPEPPOKF_00688	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
NPEPPOKF_00689	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NPEPPOKF_00690	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NPEPPOKF_00691	6.18e-197	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
NPEPPOKF_00692	6.57e-291	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
NPEPPOKF_00693	2.43e-264	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NPEPPOKF_00694	3.83e-295	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
NPEPPOKF_00695	1.92e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NPEPPOKF_00696	5.74e-172	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
NPEPPOKF_00697	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
NPEPPOKF_00698	3.55e-296	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
NPEPPOKF_00699	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
NPEPPOKF_00700	2.61e-199	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
NPEPPOKF_00701	3.17e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NPEPPOKF_00702	1.89e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
NPEPPOKF_00703	1.23e-187	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
NPEPPOKF_00704	3.81e-150	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NPEPPOKF_00705	9.47e-115	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
NPEPPOKF_00706	3.76e-184	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
NPEPPOKF_00707	1.74e-211	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
NPEPPOKF_00708	1.15e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
NPEPPOKF_00709	5.62e-316	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
NPEPPOKF_00710	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NPEPPOKF_00711	3.56e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NPEPPOKF_00712	1.57e-299	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
NPEPPOKF_00713	8.93e-291	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NPEPPOKF_00714	2.59e-277	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
NPEPPOKF_00716	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NPEPPOKF_00717	7.5e-105	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
NPEPPOKF_00718	2.15e-137	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NPEPPOKF_00719	4.02e-145	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
NPEPPOKF_00720	1.63e-104	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
NPEPPOKF_00721	1.24e-139	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
NPEPPOKF_00722	9.17e-59	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
NPEPPOKF_00723	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
NPEPPOKF_00724	7.27e-303	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
NPEPPOKF_00725	1.34e-52	-	-	-	-	-	-	-	-
NPEPPOKF_00726	2.37e-107	uspA	-	-	T	-	-	-	universal stress protein
NPEPPOKF_00727	1.1e-258	bla2	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
NPEPPOKF_00728	4.7e-207	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NPEPPOKF_00729	0.0	glpQ3	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
NPEPPOKF_00730	6.54e-273	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
NPEPPOKF_00731	7.55e-242	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NPEPPOKF_00732	3.26e-227	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
NPEPPOKF_00733	3.34e-215	hicD3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
NPEPPOKF_00734	8.69e-191	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
NPEPPOKF_00735	2.1e-151	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NPEPPOKF_00736	2.24e-239	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NPEPPOKF_00737	3.2e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
NPEPPOKF_00738	2.15e-280	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
NPEPPOKF_00739	1.04e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
NPEPPOKF_00740	1.52e-57	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
NPEPPOKF_00741	1.44e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
NPEPPOKF_00742	1.68e-132	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
NPEPPOKF_00743	4.85e-314	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NPEPPOKF_00744	5.95e-74	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
NPEPPOKF_00745	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NPEPPOKF_00746	9.14e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NPEPPOKF_00747	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NPEPPOKF_00748	2.03e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NPEPPOKF_00749	5.41e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NPEPPOKF_00750	1.81e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NPEPPOKF_00751	4.82e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
NPEPPOKF_00752	1.01e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
NPEPPOKF_00753	7.21e-145	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
NPEPPOKF_00754	2.31e-132	thgA3	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
NPEPPOKF_00755	2.49e-167	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
NPEPPOKF_00756	8.81e-205	-	-	-	S	-	-	-	Alpha beta hydrolase
NPEPPOKF_00757	1.39e-143	-	-	-	GM	-	-	-	NmrA-like family
NPEPPOKF_00758	1.74e-101	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
NPEPPOKF_00759	5.72e-207	-	-	-	K	-	-	-	Transcriptional regulator
NPEPPOKF_00760	3.78e-221	cryZ	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
NPEPPOKF_00762	0.0	nox4	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NPEPPOKF_00763	1.51e-132	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
NPEPPOKF_00764	5.11e-266	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NPEPPOKF_00765	1.27e-174	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
NPEPPOKF_00766	4.17e-204	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NPEPPOKF_00768	6.64e-109	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
NPEPPOKF_00769	2.25e-93	-	-	-	K	-	-	-	MarR family
NPEPPOKF_00770	1.49e-147	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NPEPPOKF_00771	0.000138	yjdF	-	-	S	-	-	-	Protein of unknown function (DUF2992)
NPEPPOKF_00772	1.03e-206	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPPOKF_00773	6.05e-170	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NPEPPOKF_00774	1.43e-251	-	-	-	-	-	-	-	-
NPEPPOKF_00775	5.23e-256	-	-	-	-	-	-	-	-
NPEPPOKF_00776	4.94e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPPOKF_00777	1.18e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
NPEPPOKF_00778	1.74e-251	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NPEPPOKF_00779	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NPEPPOKF_00780	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
NPEPPOKF_00781	8.64e-224	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
NPEPPOKF_00782	2.84e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
NPEPPOKF_00783	7.92e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NPEPPOKF_00784	1.15e-94	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
NPEPPOKF_00785	3.14e-109	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NPEPPOKF_00786	4.81e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
NPEPPOKF_00787	9.21e-94	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
NPEPPOKF_00788	1.09e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
NPEPPOKF_00789	2.32e-194	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NPEPPOKF_00790	1.78e-140	-	-	-	C	-	-	-	Enoyl-(Acyl carrier protein) reductase
NPEPPOKF_00791	1.42e-217	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NPEPPOKF_00792	1.84e-284	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NPEPPOKF_00793	4.35e-204	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NPEPPOKF_00794	2.61e-132	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NPEPPOKF_00795	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NPEPPOKF_00796	2.47e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
NPEPPOKF_00797	4.01e-200	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
NPEPPOKF_00798	2.29e-207	-	-	-	G	-	-	-	Fructosamine kinase
NPEPPOKF_00799	2.43e-150	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
NPEPPOKF_00800	8.2e-102	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NPEPPOKF_00801	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NPEPPOKF_00802	2.56e-76	-	-	-	-	-	-	-	-
NPEPPOKF_00803	3.13e-172	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NPEPPOKF_00804	2.04e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
NPEPPOKF_00805	5.28e-146	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
NPEPPOKF_00806	4.78e-65	-	-	-	-	-	-	-	-
NPEPPOKF_00807	1.73e-67	-	-	-	-	-	-	-	-
NPEPPOKF_00810	1.01e-158	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NPEPPOKF_00811	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NPEPPOKF_00812	1.68e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NPEPPOKF_00813	5.75e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPEPPOKF_00814	3.27e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
NPEPPOKF_00815	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPEPPOKF_00816	8.59e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
NPEPPOKF_00817	8.49e-266	pbpX2	-	-	V	-	-	-	Beta-lactamase
NPEPPOKF_00818	2.54e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NPEPPOKF_00819	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
NPEPPOKF_00820	4.52e-111	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NPEPPOKF_00821	4.42e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NPEPPOKF_00822	1.19e-169	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
NPEPPOKF_00823	2.53e-240	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
NPEPPOKF_00824	8.94e-221	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NPEPPOKF_00825	2.41e-113	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NPEPPOKF_00826	1.21e-245	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
NPEPPOKF_00827	1.19e-285	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NPEPPOKF_00828	1.63e-121	-	-	-	-	-	-	-	-
NPEPPOKF_00829	3.67e-275	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NPEPPOKF_00830	0.0	-	-	-	G	-	-	-	Major Facilitator
NPEPPOKF_00831	3.04e-71	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NPEPPOKF_00832	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NPEPPOKF_00833	3.28e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
NPEPPOKF_00834	2.95e-65	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
NPEPPOKF_00835	4.46e-275	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
NPEPPOKF_00836	9.74e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
NPEPPOKF_00837	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NPEPPOKF_00838	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NPEPPOKF_00839	4.64e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
NPEPPOKF_00840	1.13e-175	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
NPEPPOKF_00841	3.17e-190	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NPEPPOKF_00842	9.83e-113	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NPEPPOKF_00843	3.01e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
NPEPPOKF_00844	1.88e-194	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NPEPPOKF_00845	6.33e-185	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
NPEPPOKF_00846	2.92e-172	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
NPEPPOKF_00847	1.92e-239	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPEPPOKF_00848	5.67e-64	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
NPEPPOKF_00849	2.11e-171	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
NPEPPOKF_00850	8.8e-155	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
NPEPPOKF_00851	3.96e-44	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
NPEPPOKF_00852	7.68e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
NPEPPOKF_00853	7.22e-149	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NPEPPOKF_00854	7.8e-123	-	-	-	-	-	-	-	-
NPEPPOKF_00855	1.56e-276	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
NPEPPOKF_00856	1.38e-98	-	-	-	-	-	-	-	-
NPEPPOKF_00857	3.81e-87	-	-	-	-	-	-	-	-
NPEPPOKF_00858	1.14e-226	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family 2
NPEPPOKF_00859	2.19e-131	-	-	-	L	-	-	-	Helix-turn-helix domain
NPEPPOKF_00860	4.46e-281	ywtF_2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
NPEPPOKF_00861	3.82e-184	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NPEPPOKF_00862	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NPEPPOKF_00863	1.96e-293	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Cell cycle protein
NPEPPOKF_00865	4.92e-212	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
NPEPPOKF_00866	2.53e-233	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NPEPPOKF_00867	1.89e-208	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
NPEPPOKF_00868	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NPEPPOKF_00869	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NPEPPOKF_00870	7.76e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
NPEPPOKF_00871	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
NPEPPOKF_00872	0.0	-	-	-	S	ko:K06889	-	ko00000	Alpha beta
NPEPPOKF_00873	6.07e-33	-	-	-	-	-	-	-	-
NPEPPOKF_00874	4.37e-128	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
NPEPPOKF_00875	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
NPEPPOKF_00876	2.6e-212	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
NPEPPOKF_00877	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
NPEPPOKF_00878	1.53e-213	mleR	-	-	K	-	-	-	LysR family
NPEPPOKF_00879	4.54e-207	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
NPEPPOKF_00880	2.32e-121	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
NPEPPOKF_00881	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
NPEPPOKF_00882	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NPEPPOKF_00883	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
NPEPPOKF_00884	1.51e-206	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
NPEPPOKF_00885	1.23e-58	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
NPEPPOKF_00886	3.07e-241	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NPEPPOKF_00887	1.11e-263	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
NPEPPOKF_00888	8.69e-230	citR	-	-	K	-	-	-	sugar-binding domain protein
NPEPPOKF_00889	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
NPEPPOKF_00890	9.2e-215	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NPEPPOKF_00891	1.18e-66	-	-	-	-	-	-	-	-
NPEPPOKF_00892	4.26e-222	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
NPEPPOKF_00893	1.76e-180	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
NPEPPOKF_00894	2.04e-170	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NPEPPOKF_00895	3.16e-196	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NPEPPOKF_00896	6.07e-252	-	-	-	K	-	-	-	Helix-turn-helix domain
NPEPPOKF_00897	4.28e-225	ttdA	4.2.1.32	-	C	ko:K03779	ko00630,map00630	ko00000,ko00001,ko01000	Fumarate hydratase (Fumerase)
NPEPPOKF_00898	1.41e-147	-	4.2.1.2, 4.2.1.32	-	C	ko:K01676,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
NPEPPOKF_00899	1.51e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
NPEPPOKF_00900	1.49e-281	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
NPEPPOKF_00902	1.33e-255	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NPEPPOKF_00903	3.3e-235	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	DAHP synthetase I family
NPEPPOKF_00904	1.65e-211	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NPEPPOKF_00905	0.0	tkt2	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NPEPPOKF_00906	2.99e-208	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
NPEPPOKF_00907	9.14e-38	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
NPEPPOKF_00908	1.68e-221	-	-	-	S	-	-	-	Membrane
NPEPPOKF_00909	8.51e-210	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
NPEPPOKF_00910	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
NPEPPOKF_00911	4.58e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NPEPPOKF_00912	3.06e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NPEPPOKF_00913	2.29e-182	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPEPPOKF_00914	2.01e-211	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPEPPOKF_00915	1.98e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPEPPOKF_00916	3.08e-264	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NPEPPOKF_00917	3.19e-194	-	-	-	S	-	-	-	FMN_bind
NPEPPOKF_00918	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
NPEPPOKF_00919	4.42e-111	-	-	-	S	-	-	-	NusG domain II
NPEPPOKF_00920	1.41e-122	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
NPEPPOKF_00921	1.02e-233	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NPEPPOKF_00922	7.76e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
NPEPPOKF_00923	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPEPPOKF_00924	7.71e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NPEPPOKF_00925	9.65e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NPEPPOKF_00926	9.87e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NPEPPOKF_00927	1.84e-160	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NPEPPOKF_00928	5.95e-300	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NPEPPOKF_00929	1.32e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
NPEPPOKF_00930	8.44e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
NPEPPOKF_00931	5.32e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NPEPPOKF_00932	1.75e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NPEPPOKF_00933	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NPEPPOKF_00934	4.99e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NPEPPOKF_00935	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NPEPPOKF_00936	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NPEPPOKF_00937	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NPEPPOKF_00938	1.96e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NPEPPOKF_00939	1.11e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
NPEPPOKF_00940	8.29e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NPEPPOKF_00941	5.46e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NPEPPOKF_00942	3.59e-69	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NPEPPOKF_00943	1.85e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NPEPPOKF_00944	6.61e-193	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NPEPPOKF_00945	2.27e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NPEPPOKF_00946	9.83e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
NPEPPOKF_00947	1.24e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NPEPPOKF_00948	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
NPEPPOKF_00949	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NPEPPOKF_00950	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NPEPPOKF_00951	4.19e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NPEPPOKF_00952	1.48e-149	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
NPEPPOKF_00953	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPEPPOKF_00954	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPEPPOKF_00955	1.16e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NPEPPOKF_00956	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NPEPPOKF_00957	9.78e-102	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
NPEPPOKF_00965	1.62e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NPEPPOKF_00966	1.11e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
NPEPPOKF_00967	7.48e-153	dacB	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
NPEPPOKF_00968	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
NPEPPOKF_00969	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
NPEPPOKF_00970	5.68e-117	-	-	-	K	-	-	-	Transcriptional regulator
NPEPPOKF_00971	3.03e-129	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
NPEPPOKF_00972	3.88e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NPEPPOKF_00973	4.15e-153	-	-	-	I	-	-	-	phosphatase
NPEPPOKF_00974	2.34e-242	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
NPEPPOKF_00975	5.98e-302	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
NPEPPOKF_00976	1.92e-67	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
NPEPPOKF_00977	3.14e-230	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
NPEPPOKF_00978	1.4e-162	-	-	-	S	-	-	-	DJ-1/PfpI family
NPEPPOKF_00979	7.65e-121	yfbM	-	-	K	-	-	-	FR47-like protein
NPEPPOKF_00980	8.64e-195	-	-	-	EG	-	-	-	EamA-like transporter family
NPEPPOKF_00981	2.7e-79	-	-	-	S	-	-	-	Protein of unknown function
NPEPPOKF_00982	7.44e-51	-	-	-	S	-	-	-	Protein of unknown function
NPEPPOKF_00983	0.0	fusA1	-	-	J	-	-	-	elongation factor G
NPEPPOKF_00984	1.63e-152	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NPEPPOKF_00985	1.67e-220	-	-	-	K	-	-	-	WYL domain
NPEPPOKF_00986	1.25e-164	-	-	-	F	-	-	-	glutamine amidotransferase
NPEPPOKF_00987	1.65e-106	-	-	-	S	-	-	-	ASCH
NPEPPOKF_00988	0.0	hpaH	1.14.14.8, 1.14.14.9	-	Q	ko:K00483,ko:K16901	ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220	ko00000,ko00001,ko01000	4-hydroxyphenylacetate
NPEPPOKF_00989	6.86e-175	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
NPEPPOKF_00990	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
NPEPPOKF_00991	7.63e-249	pva1	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NPEPPOKF_00992	1.56e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
NPEPPOKF_00993	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
NPEPPOKF_00994	5.07e-157	ydgI	-	-	C	-	-	-	Nitroreductase family
NPEPPOKF_00995	5.74e-204	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
NPEPPOKF_00996	4.06e-211	-	-	-	S	-	-	-	KR domain
NPEPPOKF_00997	4.48e-98	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NPEPPOKF_00998	2.49e-95	-	-	-	C	-	-	-	FMN binding
NPEPPOKF_00999	1.46e-204	-	-	-	K	-	-	-	LysR family
NPEPPOKF_01000	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
NPEPPOKF_01001	0.0	-	-	-	C	-	-	-	FMN_bind
NPEPPOKF_01002	1.57e-150	-	-	-	S	-	-	-	Elongation factor G-binding protein, N-terminal
NPEPPOKF_01003	4.95e-86	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
NPEPPOKF_01004	5.63e-86	pnb	-	-	C	-	-	-	nitroreductase
NPEPPOKF_01005	4.75e-42	pnb	-	-	C	-	-	-	nitroreductase
NPEPPOKF_01006	5.97e-157	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
NPEPPOKF_01007	6.96e-214	-	-	-	L	-	-	-	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
NPEPPOKF_01008	0.0	-	-	-	C	-	-	-	Belongs to the aldehyde dehydrogenase family
NPEPPOKF_01009	3.46e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NPEPPOKF_01010	6.08e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NPEPPOKF_01011	1.5e-253	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
NPEPPOKF_01012	1.71e-200	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
NPEPPOKF_01013	3.54e-195	yycI	-	-	S	-	-	-	YycH protein
NPEPPOKF_01014	3.55e-313	yycH	-	-	S	-	-	-	YycH protein
NPEPPOKF_01015	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NPEPPOKF_01016	2.22e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
NPEPPOKF_01018	2.54e-50	-	-	-	-	-	-	-	-
NPEPPOKF_01019	4.37e-43	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein domain
NPEPPOKF_01020	3.21e-104	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
NPEPPOKF_01021	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
NPEPPOKF_01022	1.1e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
NPEPPOKF_01023	8.38e-184	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
NPEPPOKF_01024	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
NPEPPOKF_01025	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NPEPPOKF_01026	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
NPEPPOKF_01027	3.49e-269	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
NPEPPOKF_01028	6.65e-282	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NPEPPOKF_01029	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NPEPPOKF_01030	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
NPEPPOKF_01032	2.19e-290	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NPEPPOKF_01033	9e-184	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NPEPPOKF_01034	4.96e-289	yttB	-	-	EGP	-	-	-	Major Facilitator
NPEPPOKF_01035	8.77e-317	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
NPEPPOKF_01036	3.44e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
NPEPPOKF_01037	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
NPEPPOKF_01038	2.69e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NPEPPOKF_01039	1.59e-95	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NPEPPOKF_01040	5.95e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
NPEPPOKF_01043	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NPEPPOKF_01044	7.24e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NPEPPOKF_01045	3.82e-51	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
NPEPPOKF_01046	8.19e-267	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NPEPPOKF_01047	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NPEPPOKF_01048	4.62e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
NPEPPOKF_01049	3.74e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NPEPPOKF_01050	1.55e-158	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NPEPPOKF_01051	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
NPEPPOKF_01052	3.75e-305	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
NPEPPOKF_01053	2.14e-155	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
NPEPPOKF_01054	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NPEPPOKF_01055	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NPEPPOKF_01056	2.16e-142	-	-	-	S	-	-	-	Cell surface protein
NPEPPOKF_01057	2.13e-209	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
NPEPPOKF_01059	0.0	-	-	-	-	-	-	-	-
NPEPPOKF_01060	2.76e-141	sip3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NPEPPOKF_01062	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
NPEPPOKF_01063	2.89e-80	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
NPEPPOKF_01064	3.3e-202	degV1	-	-	S	-	-	-	DegV family
NPEPPOKF_01065	3.66e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NPEPPOKF_01066	1.13e-182	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
NPEPPOKF_01067	8.59e-85	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
NPEPPOKF_01068	1.56e-262	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
NPEPPOKF_01069	0.0	-	-	-	-	-	-	-	-
NPEPPOKF_01070	1.45e-260	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
NPEPPOKF_01071	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NPEPPOKF_01072	1.91e-66	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
NPEPPOKF_01073	8.61e-132	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
NPEPPOKF_01074	7.04e-108	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NPEPPOKF_01075	1.05e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
NPEPPOKF_01076	2.1e-161	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
NPEPPOKF_01077	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
NPEPPOKF_01078	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
NPEPPOKF_01079	8.43e-240	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
NPEPPOKF_01080	1.18e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
NPEPPOKF_01081	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NPEPPOKF_01082	1.8e-135	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NPEPPOKF_01083	1.29e-200	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NPEPPOKF_01084	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NPEPPOKF_01085	9.34e-201	-	-	-	S	-	-	-	Tetratricopeptide repeat
NPEPPOKF_01086	4.38e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NPEPPOKF_01087	3.21e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NPEPPOKF_01088	7.8e-300	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NPEPPOKF_01089	9.6e-143	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
NPEPPOKF_01090	1.3e-65	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
NPEPPOKF_01091	6.47e-95	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
NPEPPOKF_01092	5.12e-31	-	-	-	-	-	-	-	-
NPEPPOKF_01093	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
NPEPPOKF_01094	3.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NPEPPOKF_01095	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NPEPPOKF_01096	8.45e-162	epsB	-	-	M	-	-	-	biosynthesis protein
NPEPPOKF_01097	2.02e-156	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
NPEPPOKF_01098	5.54e-189	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
NPEPPOKF_01099	8.71e-231	cps4D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
NPEPPOKF_01100	3.18e-162	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
NPEPPOKF_01101	1.43e-223	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
NPEPPOKF_01102	1.82e-132	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
NPEPPOKF_01103	7.88e-48	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
NPEPPOKF_01104	1.91e-297	-	-	-	-	-	-	-	-
NPEPPOKF_01105	4.82e-228	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
NPEPPOKF_01106	0.0	cps4J	-	-	S	-	-	-	MatE
NPEPPOKF_01107	0.0	-	3.1.4.53	-	S	ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
NPEPPOKF_01108	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
NPEPPOKF_01109	4.24e-218	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NPEPPOKF_01110	3.02e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
NPEPPOKF_01111	1.55e-311	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NPEPPOKF_01112	6.62e-62	-	-	-	-	-	-	-	-
NPEPPOKF_01113	8.34e-228	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NPEPPOKF_01114	7.09e-180	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
NPEPPOKF_01115	1.84e-67	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
NPEPPOKF_01116	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
NPEPPOKF_01117	1.52e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NPEPPOKF_01118	3.58e-129	-	-	-	K	-	-	-	Helix-turn-helix domain
NPEPPOKF_01119	1.66e-269	-	-	-	EGP	-	-	-	Major facilitator Superfamily
NPEPPOKF_01120	2.84e-75	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
NPEPPOKF_01121	2.21e-178	-	-	-	Q	-	-	-	Methyltransferase
NPEPPOKF_01122	5.03e-43	-	-	-	-	-	-	-	-
NPEPPOKF_01123	6.15e-75	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NPEPPOKF_01130	2.59e-99	-	-	-	K	-	-	-	Peptidase S24-like
NPEPPOKF_01131	1.56e-27	-	-	-	-	-	-	-	-
NPEPPOKF_01134	7.34e-80	-	-	-	S	-	-	-	DNA binding
NPEPPOKF_01141	2e-25	-	-	-	-	-	-	-	-
NPEPPOKF_01143	4.24e-188	-	-	-	S	-	-	-	Protein of unknown function (DUF1351)
NPEPPOKF_01144	3.98e-151	-	-	-	S	-	-	-	AAA domain
NPEPPOKF_01145	3.13e-127	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
NPEPPOKF_01146	2.93e-167	-	-	-	S	-	-	-	Putative HNHc nuclease
NPEPPOKF_01147	2.84e-169	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
NPEPPOKF_01149	4.01e-87	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
NPEPPOKF_01150	2.95e-06	-	-	-	-	-	-	-	-
NPEPPOKF_01152	8.89e-118	-	-	-	L	-	-	-	C-5 cytosine-specific DNA methylase
NPEPPOKF_01154	1.28e-09	-	-	-	S	-	-	-	YopX protein
NPEPPOKF_01155	5.27e-72	-	-	-	-	-	-	-	-
NPEPPOKF_01156	2.2e-23	-	-	-	-	-	-	-	-
NPEPPOKF_01157	1.13e-84	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
NPEPPOKF_01158	7.81e-113	-	-	-	L	-	-	-	HNH nucleases
NPEPPOKF_01160	6.68e-103	-	-	-	L	-	-	-	Phage terminase, small subunit
NPEPPOKF_01161	0.0	-	-	-	S	-	-	-	Phage Terminase
NPEPPOKF_01162	6.68e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF1056)
NPEPPOKF_01163	6.97e-284	-	-	-	S	-	-	-	Phage portal protein
NPEPPOKF_01164	5.99e-164	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
NPEPPOKF_01165	1.03e-254	-	-	-	S	-	-	-	Phage capsid family
NPEPPOKF_01166	9.36e-65	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
NPEPPOKF_01167	3.45e-76	-	-	-	S	-	-	-	Phage head-tail joining protein
NPEPPOKF_01168	2.25e-86	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
NPEPPOKF_01169	7.47e-74	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
NPEPPOKF_01170	2.16e-131	-	-	-	S	-	-	-	Phage tail tube protein
NPEPPOKF_01171	1.35e-75	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
NPEPPOKF_01172	6.36e-34	-	-	-	-	-	-	-	-
NPEPPOKF_01173	0.0	-	-	-	D	-	-	-	domain protein
NPEPPOKF_01174	0.0	-	-	-	S	-	-	-	Phage tail protein
NPEPPOKF_01175	0.0	-	-	-	S	-	-	-	Phage minor structural protein
NPEPPOKF_01179	1.93e-102	-	-	-	-	-	-	-	-
NPEPPOKF_01180	2.91e-29	-	-	-	-	-	-	-	-
NPEPPOKF_01181	6.18e-191	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
NPEPPOKF_01182	1.66e-101	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NPEPPOKF_01183	3.46e-267	mccF	-	-	V	-	-	-	LD-carboxypeptidase
NPEPPOKF_01184	9.63e-307	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
NPEPPOKF_01185	9.19e-95	-	-	-	S	-	-	-	SnoaL-like domain
NPEPPOKF_01186	4.17e-186	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
NPEPPOKF_01187	1.55e-309	-	-	-	P	-	-	-	Major Facilitator Superfamily
NPEPPOKF_01188	1.26e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
NPEPPOKF_01189	1.44e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
NPEPPOKF_01191	9.98e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NPEPPOKF_01192	2.12e-142	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
NPEPPOKF_01193	3.6e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NPEPPOKF_01194	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
NPEPPOKF_01195	4.64e-228	phnT	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NPEPPOKF_01196	8.06e-234	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NPEPPOKF_01197	0.0	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NPEPPOKF_01198	5.32e-109	-	-	-	T	-	-	-	Universal stress protein family
NPEPPOKF_01199	1.58e-203	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
NPEPPOKF_01200	2.45e-142	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NPEPPOKF_01201	2.32e-238	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NPEPPOKF_01203	9.32e-165	dnaD	-	-	L	ko:K02086	-	ko00000	Replication initiation and membrane attachment
NPEPPOKF_01204	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
NPEPPOKF_01205	3.1e-289	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
NPEPPOKF_01206	2.53e-107	ypmB	-	-	S	-	-	-	protein conserved in bacteria
NPEPPOKF_01207	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
NPEPPOKF_01208	2.61e-141	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
NPEPPOKF_01209	1.1e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
NPEPPOKF_01210	2.94e-261	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
NPEPPOKF_01211	8.61e-251	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NPEPPOKF_01212	3.36e-247	galM2	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
NPEPPOKF_01213	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
NPEPPOKF_01214	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
NPEPPOKF_01215	3.24e-155	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
NPEPPOKF_01216	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
NPEPPOKF_01217	3.86e-192	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
NPEPPOKF_01218	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
NPEPPOKF_01219	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NPEPPOKF_01220	3.23e-58	-	-	-	-	-	-	-	-
NPEPPOKF_01221	1.25e-66	-	-	-	-	-	-	-	-
NPEPPOKF_01222	5.03e-182	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
NPEPPOKF_01223	1.48e-218	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
NPEPPOKF_01224	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NPEPPOKF_01225	8.39e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
NPEPPOKF_01226	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NPEPPOKF_01227	1.06e-53	-	-	-	-	-	-	-	-
NPEPPOKF_01228	4e-40	-	-	-	S	-	-	-	CsbD-like
NPEPPOKF_01229	2.22e-55	-	-	-	S	-	-	-	transglycosylase associated protein
NPEPPOKF_01230	5.79e-21	-	-	-	-	-	-	-	-
NPEPPOKF_01231	8.76e-48	-	-	-	-	-	-	-	-
NPEPPOKF_01232	1.21e-209	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
NPEPPOKF_01233	5.58e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
NPEPPOKF_01234	5.28e-100	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
NPEPPOKF_01235	6.05e-108	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
NPEPPOKF_01236	2.05e-55	-	-	-	-	-	-	-	-
NPEPPOKF_01237	5.93e-60	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
NPEPPOKF_01238	9.96e-147	-	1.14.99.53	AA10	S	ko:K21713	-	ko00000,ko01000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
NPEPPOKF_01239	3.2e-37	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
NPEPPOKF_01240	6.57e-274	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
NPEPPOKF_01241	2.02e-39	-	-	-	-	-	-	-	-
NPEPPOKF_01242	1.48e-71	-	-	-	-	-	-	-	-
NPEPPOKF_01243	1.14e-193	-	-	-	O	-	-	-	Band 7 protein
NPEPPOKF_01244	0.0	-	-	-	EGP	-	-	-	Major Facilitator
NPEPPOKF_01245	4.09e-119	-	-	-	K	-	-	-	transcriptional regulator
NPEPPOKF_01246	4.4e-246	rsgA_2	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NPEPPOKF_01247	2.01e-113	ykhA	-	-	I	-	-	-	Thioesterase superfamily
NPEPPOKF_01248	7.52e-207	-	-	-	K	-	-	-	LysR substrate binding domain
NPEPPOKF_01249	1.48e-161	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
NPEPPOKF_01250	5.01e-129	-	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
NPEPPOKF_01251	2.29e-175	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
NPEPPOKF_01252	4.82e-179	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
NPEPPOKF_01253	6.43e-203	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NPEPPOKF_01254	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
NPEPPOKF_01255	1.71e-91	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
NPEPPOKF_01256	2.14e-95	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NPEPPOKF_01257	1.8e-288	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NPEPPOKF_01258	1.26e-162	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
NPEPPOKF_01259	3.47e-215	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
NPEPPOKF_01260	6.16e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NPEPPOKF_01261	1.62e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NPEPPOKF_01262	8.55e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NPEPPOKF_01263	1.62e-229	yneE	-	-	K	-	-	-	Transcriptional regulator
NPEPPOKF_01264	6.84e-186	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
NPEPPOKF_01266	1.49e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
NPEPPOKF_01267	2.69e-252	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
NPEPPOKF_01268	3.38e-274	hipO1	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	Peptidase family M20/M25/M40
NPEPPOKF_01269	1.62e-276	-	-	-	E	-	-	-	glutamate:sodium symporter activity
NPEPPOKF_01270	1.95e-88	ybbJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
NPEPPOKF_01271	1.36e-210	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
NPEPPOKF_01272	5.89e-126	entB	-	-	Q	-	-	-	Isochorismatase family
NPEPPOKF_01273	4.82e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NPEPPOKF_01274	5.13e-287	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NPEPPOKF_01275	1.57e-142	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
NPEPPOKF_01276	2.41e-165	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
NPEPPOKF_01277	6.03e-226	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NPEPPOKF_01278	8.08e-135	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
NPEPPOKF_01279	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
NPEPPOKF_01281	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
NPEPPOKF_01282	2.05e-179	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
NPEPPOKF_01283	9.06e-112	-	-	-	-	-	-	-	-
NPEPPOKF_01284	2.81e-194	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
NPEPPOKF_01285	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NPEPPOKF_01286	1.56e-46	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
NPEPPOKF_01287	3.91e-289	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NPEPPOKF_01288	2.29e-292	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NPEPPOKF_01289	2.16e-241	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NPEPPOKF_01290	2.04e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
NPEPPOKF_01291	1.41e-285	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
NPEPPOKF_01292	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NPEPPOKF_01293	1.24e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
NPEPPOKF_01294	5.6e-41	-	-	-	-	-	-	-	-
NPEPPOKF_01295	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
NPEPPOKF_01296	3.29e-95	-	-	-	L	-	-	-	Integrase
NPEPPOKF_01297	3.4e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
NPEPPOKF_01298	5.67e-231	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NPEPPOKF_01299	4.86e-258	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NPEPPOKF_01300	3.59e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPEPPOKF_01301	3.44e-210	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPEPPOKF_01302	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
NPEPPOKF_01303	3.85e-76	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
NPEPPOKF_01304	1.01e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NPEPPOKF_01305	1.36e-208	lysR5	-	-	K	-	-	-	LysR substrate binding domain
NPEPPOKF_01306	1.01e-250	-	-	-	M	-	-	-	MucBP domain
NPEPPOKF_01307	0.0	-	-	-	-	-	-	-	-
NPEPPOKF_01308	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NPEPPOKF_01309	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
NPEPPOKF_01310	1.22e-218	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
NPEPPOKF_01311	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
NPEPPOKF_01312	7.89e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
NPEPPOKF_01313	6.04e-94	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
NPEPPOKF_01314	1.13e-257	yueF	-	-	S	-	-	-	AI-2E family transporter
NPEPPOKF_01315	7.3e-216	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
NPEPPOKF_01316	7.17e-39	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
NPEPPOKF_01317	3.97e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
NPEPPOKF_01318	1.94e-170	lytE	-	-	M	-	-	-	NlpC/P60 family
NPEPPOKF_01319	6.62e-138	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
NPEPPOKF_01320	1.01e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
NPEPPOKF_01321	1.34e-168	-	-	-	-	-	-	-	-
NPEPPOKF_01322	1.68e-131	-	-	-	K	-	-	-	DNA-templated transcription, initiation
NPEPPOKF_01323	3.31e-35	-	-	-	-	-	-	-	-
NPEPPOKF_01324	1.95e-41	-	-	-	-	-	-	-	-
NPEPPOKF_01325	1.04e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
NPEPPOKF_01326	9.02e-70	-	-	-	-	-	-	-	-
NPEPPOKF_01328	3.98e-169	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
NPEPPOKF_01329	1.95e-197	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
NPEPPOKF_01330	3.34e-267	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NPEPPOKF_01331	3.3e-281	pbpX	-	-	V	-	-	-	Beta-lactamase
NPEPPOKF_01332	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
NPEPPOKF_01333	8.31e-139	-	-	-	-	-	-	-	-
NPEPPOKF_01334	7.62e-97	-	-	-	-	-	-	-	-
NPEPPOKF_01336	3.21e-209	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NPEPPOKF_01337	3.15e-313	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPEPPOKF_01338	3.93e-99	-	-	-	T	-	-	-	Universal stress protein family
NPEPPOKF_01340	5.62e-316	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
NPEPPOKF_01341	7.89e-245	mocA	-	-	S	-	-	-	Oxidoreductase
NPEPPOKF_01342	6.22e-43	cspP	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
NPEPPOKF_01343	7.34e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
NPEPPOKF_01344	2.22e-185	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
NPEPPOKF_01345	5.63e-196	gntR	-	-	K	-	-	-	rpiR family
NPEPPOKF_01346	2.87e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NPEPPOKF_01347	7.06e-307	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPEPPOKF_01348	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
NPEPPOKF_01349	2.26e-129	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NPEPPOKF_01350	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NPEPPOKF_01351	1.59e-242	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
NPEPPOKF_01352	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NPEPPOKF_01353	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NPEPPOKF_01354	5.11e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NPEPPOKF_01355	9.48e-263	camS	-	-	S	-	-	-	sex pheromone
NPEPPOKF_01356	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NPEPPOKF_01357	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
NPEPPOKF_01358	1.39e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NPEPPOKF_01359	1.13e-120	yebE	-	-	S	-	-	-	UPF0316 protein
NPEPPOKF_01360	2.01e-134	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NPEPPOKF_01361	1.97e-145	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
NPEPPOKF_01362	7.78e-235	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
NPEPPOKF_01363	1.37e-83	-	-	-	K	-	-	-	Helix-turn-helix domain
NPEPPOKF_01364	1.08e-71	-	-	-	-	-	-	-	-
NPEPPOKF_01365	1.66e-96	-	-	-	-	-	-	-	-
NPEPPOKF_01366	6.67e-30	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
NPEPPOKF_01367	8.56e-38	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
NPEPPOKF_01368	9.16e-61	-	-	-	L	-	-	-	Helix-turn-helix domain
NPEPPOKF_01370	3.56e-171	spoVK	-	-	O	ko:K06413	-	ko00000	ATPase family associated with various cellular activities (AAA)
NPEPPOKF_01372	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
NPEPPOKF_01373	1.22e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
NPEPPOKF_01374	8.45e-211	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
NPEPPOKF_01375	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
NPEPPOKF_01376	4.51e-143	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
NPEPPOKF_01377	4.16e-227	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
NPEPPOKF_01378	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
NPEPPOKF_01379	2.07e-161	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
NPEPPOKF_01380	1.35e-165	pgm3	-	-	G	-	-	-	Phosphoglycerate mutase family
NPEPPOKF_01381	1.61e-36	-	-	-	-	-	-	-	-
NPEPPOKF_01382	3.5e-64	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
NPEPPOKF_01383	4.6e-102	rppH3	-	-	F	-	-	-	NUDIX domain
NPEPPOKF_01384	5.95e-300	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NPEPPOKF_01385	1.81e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NPEPPOKF_01386	2.93e-109	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NPEPPOKF_01387	3.22e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NPEPPOKF_01388	7.26e-92	-	-	-	K	-	-	-	MarR family
NPEPPOKF_01389	8.87e-191	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
NPEPPOKF_01390	6.26e-96	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NPEPPOKF_01391	9.38e-317	steT	-	-	E	ko:K03294	-	ko00000	amino acid
NPEPPOKF_01392	4.87e-180	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
NPEPPOKF_01393	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
NPEPPOKF_01394	7.77e-197	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
NPEPPOKF_01395	7.04e-108	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NPEPPOKF_01396	1.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NPEPPOKF_01397	3.14e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NPEPPOKF_01398	3.39e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
NPEPPOKF_01399	2.3e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NPEPPOKF_01401	1.28e-54	-	-	-	-	-	-	-	-
NPEPPOKF_01402	2.07e-217	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPEPPOKF_01403	1.05e-234	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NPEPPOKF_01404	1.94e-95	gph1	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant
NPEPPOKF_01405	1.01e-188	-	-	-	-	-	-	-	-
NPEPPOKF_01406	8.84e-18	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
NPEPPOKF_01407	2.02e-106	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
NPEPPOKF_01408	2.45e-134	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
NPEPPOKF_01409	1.48e-27	-	-	-	-	-	-	-	-
NPEPPOKF_01410	7.48e-96	-	-	-	F	-	-	-	Nudix hydrolase
NPEPPOKF_01411	1.23e-189	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
NPEPPOKF_01412	6.12e-115	-	-	-	-	-	-	-	-
NPEPPOKF_01413	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
NPEPPOKF_01414	3.8e-61	-	-	-	-	-	-	-	-
NPEPPOKF_01415	1.55e-89	-	-	-	O	-	-	-	OsmC-like protein
NPEPPOKF_01416	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NPEPPOKF_01417	0.0	oatA	-	-	I	-	-	-	Acyltransferase
NPEPPOKF_01418	5.01e-229	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NPEPPOKF_01419	3.45e-231	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
NPEPPOKF_01420	0.0	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
NPEPPOKF_01421	5.47e-198	ribC1	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
NPEPPOKF_01422	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
NPEPPOKF_01423	1.79e-287	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
NPEPPOKF_01424	1.36e-27	-	-	-	-	-	-	-	-
NPEPPOKF_01425	3.68e-107	-	-	-	K	-	-	-	Transcriptional regulator
NPEPPOKF_01426	7.8e-196	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
NPEPPOKF_01427	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
NPEPPOKF_01428	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NPEPPOKF_01429	4.45e-226	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
NPEPPOKF_01430	3.49e-315	-	-	-	EGP	-	-	-	Major Facilitator
NPEPPOKF_01431	1.71e-116	-	-	-	V	-	-	-	VanZ like family
NPEPPOKF_01432	3.88e-46	-	-	-	-	-	-	-	-
NPEPPOKF_01433	5.45e-94	spx1	-	-	P	ko:K16509	-	ko00000	ArsC family
NPEPPOKF_01435	6.37e-186	-	-	-	-	-	-	-	-
NPEPPOKF_01436	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NPEPPOKF_01437	7.08e-197	-	-	-	G	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
NPEPPOKF_01438	2.87e-168	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
NPEPPOKF_01439	2.49e-95	-	-	-	-	-	-	-	-
NPEPPOKF_01440	3.38e-70	-	-	-	-	-	-	-	-
NPEPPOKF_01441	1.46e-263	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
NPEPPOKF_01442	1.21e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NPEPPOKF_01443	8.04e-190	-	3.1.3.23	-	S	ko:K07757	-	ko00000,ko01000	Sucrose-6F-phosphate phosphohydrolase
NPEPPOKF_01444	5.44e-159	-	-	-	T	-	-	-	EAL domain
NPEPPOKF_01445	7.81e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NPEPPOKF_01446	3.04e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NPEPPOKF_01447	1.79e-243	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NPEPPOKF_01448	3.44e-204	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NPEPPOKF_01449	1.88e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NPEPPOKF_01450	1.54e-141	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
NPEPPOKF_01451	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
NPEPPOKF_01452	3.04e-174	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
NPEPPOKF_01453	4.07e-249	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
NPEPPOKF_01454	3.76e-245	ampC	-	-	V	-	-	-	Beta-lactamase
NPEPPOKF_01455	8.57e-41	-	-	-	-	-	-	-	-
NPEPPOKF_01456	1.9e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
NPEPPOKF_01457	1.33e-77	-	-	-	-	-	-	-	-
NPEPPOKF_01458	1.08e-181	-	-	-	-	-	-	-	-
NPEPPOKF_01459	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
NPEPPOKF_01460	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NPEPPOKF_01461	1.81e-85	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
NPEPPOKF_01462	2.91e-177	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
NPEPPOKF_01463	2.93e-73	-	-	-	V	-	-	-	Abortive infection bacteriophage resistance protein
NPEPPOKF_01464	5.11e-59	-	-	-	S	-	-	-	Bacteriophage holin
NPEPPOKF_01465	1.7e-255	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
NPEPPOKF_01467	1.4e-27	-	-	-	-	-	-	-	-
NPEPPOKF_01468	1.4e-108	-	-	-	-	-	-	-	-
NPEPPOKF_01472	8.28e-127	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
NPEPPOKF_01473	2.64e-220	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
NPEPPOKF_01474	0.0	-	-	-	M	-	-	-	Prophage endopeptidase tail
NPEPPOKF_01475	9.72e-173	-	-	-	S	-	-	-	phage tail
NPEPPOKF_01476	0.0	-	-	-	D	-	-	-	domain protein
NPEPPOKF_01478	5.37e-107	-	-	-	S	-	-	-	Phage tail assembly chaperone protein, TAC
NPEPPOKF_01479	2.09e-123	-	-	-	-	-	-	-	-
NPEPPOKF_01480	5.59e-81	-	-	-	-	-	-	-	-
NPEPPOKF_01481	9.66e-123	-	-	-	-	-	-	-	-
NPEPPOKF_01482	5.46e-67	-	-	-	-	-	-	-	-
NPEPPOKF_01483	3.11e-75	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
NPEPPOKF_01484	2.45e-247	gpG	-	-	-	-	-	-	-
NPEPPOKF_01485	2.66e-110	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
NPEPPOKF_01486	5.76e-216	-	-	-	S	-	-	-	Phage Mu protein F like protein
NPEPPOKF_01487	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
NPEPPOKF_01488	2.91e-316	-	-	-	S	ko:K06909	-	ko00000	Phage terminase, large subunit
NPEPPOKF_01490	3.13e-98	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
NPEPPOKF_01493	7.56e-25	-	-	-	-	-	-	-	-
NPEPPOKF_01494	1.15e-40	-	-	-	S	-	-	-	ASCH
NPEPPOKF_01495	2.49e-97	-	-	-	K	-	-	-	acetyltransferase
NPEPPOKF_01500	3.54e-18	-	-	-	S	-	-	-	YopX protein
NPEPPOKF_01502	9.03e-83	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
NPEPPOKF_01503	3.24e-67	-	-	-	-	-	-	-	-
NPEPPOKF_01504	7.28e-213	-	-	-	L	-	-	-	DnaD domain protein
NPEPPOKF_01505	6.45e-80	-	-	-	-	-	-	-	-
NPEPPOKF_01506	8e-70	-	-	-	S	-	-	-	Bacteriophage Mu Gam like protein
NPEPPOKF_01508	2.15e-110	-	-	-	-	-	-	-	-
NPEPPOKF_01509	6.59e-72	-	-	-	-	-	-	-	-
NPEPPOKF_01511	7.19e-51	-	-	-	K	-	-	-	Helix-turn-helix
NPEPPOKF_01512	2.67e-80	-	-	-	K	-	-	-	Helix-turn-helix domain
NPEPPOKF_01513	1.92e-97	-	-	-	E	-	-	-	IrrE N-terminal-like domain
NPEPPOKF_01514	2.69e-38	-	-	-	S	-	-	-	TerB N-terminal domain
NPEPPOKF_01516	4.23e-19	-	-	-	S	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
NPEPPOKF_01520	9.38e-279	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NPEPPOKF_01522	1.98e-40	-	-	-	-	-	-	-	-
NPEPPOKF_01525	1.02e-80	-	-	-	-	-	-	-	-
NPEPPOKF_01526	1.75e-48	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
NPEPPOKF_01527	0.0	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
NPEPPOKF_01528	6.16e-260	-	-	-	S	-	-	-	Phage portal protein
NPEPPOKF_01530	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
NPEPPOKF_01531	1.9e-109	terS	-	-	L	-	-	-	Phage terminase, small subunit
NPEPPOKF_01532	1.05e-88	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	Phage-associated protein
NPEPPOKF_01533	3.24e-62	-	-	-	S	-	-	-	Head-tail joining protein
NPEPPOKF_01535	3.36e-96	-	-	-	-	-	-	-	-
NPEPPOKF_01536	0.0	-	-	-	S	-	-	-	Virulence-associated protein E
NPEPPOKF_01537	1.5e-187	-	-	-	L	-	-	-	DNA replication protein
NPEPPOKF_01538	2.62e-40	-	-	-	-	-	-	-	-
NPEPPOKF_01541	1.1e-06	-	-	-	K	ko:K07727	-	ko00000,ko03000	transcriptional regulator
NPEPPOKF_01542	1.79e-289	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NPEPPOKF_01543	1.28e-51	-	-	-	-	-	-	-	-
NPEPPOKF_01544	9.28e-58	-	-	-	-	-	-	-	-
NPEPPOKF_01545	1.27e-109	-	-	-	K	-	-	-	MarR family
NPEPPOKF_01546	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
NPEPPOKF_01547	2.55e-217	inlJ	-	-	M	-	-	-	MucBP domain
NPEPPOKF_01548	9.05e-22	-	-	-	-	-	-	-	-
NPEPPOKF_01549	2.69e-23	-	-	-	-	-	-	-	-
NPEPPOKF_01550	5.72e-21	-	-	-	-	-	-	-	-
NPEPPOKF_01551	6.21e-26	-	-	-	-	-	-	-	-
NPEPPOKF_01552	4.63e-24	-	-	-	-	-	-	-	-
NPEPPOKF_01563	3.26e-119	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
NPEPPOKF_01564	6.36e-237	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
NPEPPOKF_01565	1.25e-124	-	-	-	-	-	-	-	-
NPEPPOKF_01566	1.58e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NPEPPOKF_01567	2.98e-46	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
NPEPPOKF_01568	3.47e-134	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
NPEPPOKF_01570	2.19e-291	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
NPEPPOKF_01571	6.21e-241	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
NPEPPOKF_01572	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
NPEPPOKF_01573	2.75e-216	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
NPEPPOKF_01574	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
NPEPPOKF_01575	3.35e-157	-	-	-	-	-	-	-	-
NPEPPOKF_01576	2.78e-273	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NPEPPOKF_01577	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
NPEPPOKF_01578	1.37e-60	-	-	-	N	-	-	-	Cell shape-determining protein MreB
NPEPPOKF_01579	1.21e-185	-	-	-	N	-	-	-	Cell shape-determining protein MreB
NPEPPOKF_01580	0.0	-	-	-	S	-	-	-	Pfam Methyltransferase
NPEPPOKF_01581	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
NPEPPOKF_01582	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
NPEPPOKF_01583	9.32e-40	-	-	-	-	-	-	-	-
NPEPPOKF_01584	3.03e-122	mraW1	-	-	J	-	-	-	Putative rRNA methylase
NPEPPOKF_01585	3.58e-161	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
NPEPPOKF_01586	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
NPEPPOKF_01587	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
NPEPPOKF_01588	5.04e-176	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NPEPPOKF_01589	3.03e-193	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NPEPPOKF_01590	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
NPEPPOKF_01591	2.16e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
NPEPPOKF_01592	2.92e-258	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
NPEPPOKF_01593	1.13e-221	ugpA	-	-	U	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NPEPPOKF_01594	3.05e-193	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NPEPPOKF_01595	5.01e-229	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NPEPPOKF_01596	2.07e-155	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
NPEPPOKF_01597	3.55e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NPEPPOKF_01598	3e-315	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
NPEPPOKF_01600	3.34e-160	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
NPEPPOKF_01601	3.06e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NPEPPOKF_01602	2.57e-226	-	-	-	K	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
NPEPPOKF_01604	6.96e-198	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NPEPPOKF_01605	5.2e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NPEPPOKF_01606	1.64e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
NPEPPOKF_01607	9.36e-205	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NPEPPOKF_01608	1.89e-189	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NPEPPOKF_01609	7.83e-140	-	-	-	-	-	-	-	-
NPEPPOKF_01610	2.08e-283	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
NPEPPOKF_01611	9.01e-179	agrA	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
NPEPPOKF_01612	5.37e-74	-	-	-	-	-	-	-	-
NPEPPOKF_01613	4.56e-78	-	-	-	-	-	-	-	-
NPEPPOKF_01614	1.23e-145	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NPEPPOKF_01615	2.2e-111	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
NPEPPOKF_01616	8.82e-119	-	-	-	-	-	-	-	-
NPEPPOKF_01617	7.12e-62	-	-	-	-	-	-	-	-
NPEPPOKF_01618	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
NPEPPOKF_01621	4.29e-87	-	-	-	-	-	-	-	-
NPEPPOKF_01622	9.03e-16	-	-	-	-	-	-	-	-
NPEPPOKF_01623	3.89e-237	-	-	-	-	-	-	-	-
NPEPPOKF_01624	4.91e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
NPEPPOKF_01625	8.01e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
NPEPPOKF_01626	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NPEPPOKF_01627	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NPEPPOKF_01628	0.0	-	-	-	S	-	-	-	Protein conserved in bacteria
NPEPPOKF_01629	7.32e-292	sat	2.7.7.4	-	H	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
NPEPPOKF_01630	3.72e-145	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
NPEPPOKF_01631	2.54e-225	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
NPEPPOKF_01632	0.0	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
NPEPPOKF_01633	0.0	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
NPEPPOKF_01634	4.75e-157	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NPEPPOKF_01635	1.13e-171	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
NPEPPOKF_01636	4.87e-156	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NPEPPOKF_01637	4.32e-294	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
NPEPPOKF_01638	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
NPEPPOKF_01639	1.96e-137	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
NPEPPOKF_01640	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
NPEPPOKF_01641	1.17e-135	-	-	-	K	-	-	-	transcriptional regulator
NPEPPOKF_01642	2.04e-158	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
NPEPPOKF_01643	1.49e-63	-	-	-	-	-	-	-	-
NPEPPOKF_01644	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
NPEPPOKF_01645	5.06e-236	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
NPEPPOKF_01646	2.87e-56	-	-	-	-	-	-	-	-
NPEPPOKF_01647	1.6e-73	-	-	-	-	-	-	-	-
NPEPPOKF_01648	6.86e-311	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPEPPOKF_01649	2.78e-167	yidA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
NPEPPOKF_01650	9.86e-65	-	-	-	-	-	-	-	-
NPEPPOKF_01651	2.58e-163	rrp2	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
NPEPPOKF_01652	1.72e-315	hpk2	-	-	T	-	-	-	Histidine kinase
NPEPPOKF_01653	2.2e-86	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NPEPPOKF_01654	0.0	ydiC	-	-	EGP	-	-	-	Major Facilitator
NPEPPOKF_01655	3.13e-55	-	-	-	-	-	-	-	-
NPEPPOKF_01656	6.37e-52	-	-	-	-	-	-	-	-
NPEPPOKF_01657	4.5e-150	-	-	-	-	-	-	-	-
NPEPPOKF_01658	4.02e-301	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
NPEPPOKF_01659	8.62e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NPEPPOKF_01660	8.9e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
NPEPPOKF_01661	2.73e-92	-	-	-	-	-	-	-	-
NPEPPOKF_01662	3.37e-129	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NPEPPOKF_01663	0.0	tagF2	2.7.8.12	-	H	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NPEPPOKF_01664	5.71e-306	tagB	2.7.8.12, 2.7.8.45	-	M	ko:K09809,ko:K21591	-	ko00000,ko01000	glycerophosphotransferase
NPEPPOKF_01665	1.21e-94	tagD	2.7.7.15, 2.7.7.39	-	IM	ko:K00968,ko:K00980	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Glycerol-3-phosphate cytidylyltransferase
NPEPPOKF_01666	2.6e-185	-	-	-	-	-	-	-	-
NPEPPOKF_01667	0.0	pts5ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
NPEPPOKF_01668	0.0	pts4ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NPEPPOKF_01669	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
NPEPPOKF_01670	1.68e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
NPEPPOKF_01671	6.35e-56	-	-	-	-	-	-	-	-
NPEPPOKF_01672	7.55e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
NPEPPOKF_01673	1.27e-181	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
NPEPPOKF_01674	6.72e-203	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
NPEPPOKF_01675	2.52e-209	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
NPEPPOKF_01676	7.87e-266	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
NPEPPOKF_01677	2.13e-124	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
NPEPPOKF_01678	1.82e-126	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
NPEPPOKF_01679	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
NPEPPOKF_01680	2.41e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
NPEPPOKF_01681	1.73e-89	-	-	-	-	-	-	-	-
NPEPPOKF_01682	2.37e-123	-	-	-	-	-	-	-	-
NPEPPOKF_01683	5.92e-67	-	-	-	-	-	-	-	-
NPEPPOKF_01684	4.81e-76	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
NPEPPOKF_01685	1.21e-111	-	-	-	-	-	-	-	-
NPEPPOKF_01686	1.76e-280	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
NPEPPOKF_01687	5.33e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPEPPOKF_01688	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
NPEPPOKF_01689	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NPEPPOKF_01690	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NPEPPOKF_01691	7.02e-126	-	-	-	K	-	-	-	Helix-turn-helix domain
NPEPPOKF_01692	3.91e-283	-	-	-	C	-	-	-	FAD dependent oxidoreductase
NPEPPOKF_01693	1.82e-220	-	-	-	P	-	-	-	Major Facilitator Superfamily
NPEPPOKF_01694	3.16e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NPEPPOKF_01695	2.32e-43	ygzD	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
NPEPPOKF_01696	1.2e-91	-	-	-	-	-	-	-	-
NPEPPOKF_01697	1.05e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NPEPPOKF_01698	5.3e-202	dkgB	-	-	S	-	-	-	reductase
NPEPPOKF_01699	6.07e-117	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
NPEPPOKF_01700	2.02e-131	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC transporter permease
NPEPPOKF_01701	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NPEPPOKF_01702	1.5e-150	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
NPEPPOKF_01703	9.01e-215	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
NPEPPOKF_01704	7.76e-181	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
NPEPPOKF_01705	2.38e-99	-	-	-	-	-	-	-	-
NPEPPOKF_01706	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
NPEPPOKF_01707	2.4e-180	-	-	-	-	-	-	-	-
NPEPPOKF_01708	4.07e-05	-	-	-	-	-	-	-	-
NPEPPOKF_01709	5.66e-184	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
NPEPPOKF_01710	1.67e-54	-	-	-	-	-	-	-	-
NPEPPOKF_01711	4.29e-166	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NPEPPOKF_01712	9.79e-192	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
NPEPPOKF_01713	1.84e-235	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
NPEPPOKF_01714	1.15e-155	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
NPEPPOKF_01715	7.9e-306	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
NPEPPOKF_01716	1.78e-160	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
NPEPPOKF_01717	3.58e-174	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
NPEPPOKF_01718	1.19e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
NPEPPOKF_01719	2.6e-193	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
NPEPPOKF_01720	7.11e-227	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
NPEPPOKF_01722	1.87e-175	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NPEPPOKF_01723	7.44e-192	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NPEPPOKF_01724	1.61e-144	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NPEPPOKF_01725	1.45e-261	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
NPEPPOKF_01726	2.39e-174	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
NPEPPOKF_01727	0.0	-	-	-	L	-	-	-	HIRAN domain
NPEPPOKF_01728	1.24e-109	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
NPEPPOKF_01729	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
NPEPPOKF_01730	5.18e-159	-	-	-	-	-	-	-	-
NPEPPOKF_01731	2.07e-191	-	-	-	I	-	-	-	Alpha/beta hydrolase family
NPEPPOKF_01732	0.0	pacL1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
NPEPPOKF_01733	1.34e-183	-	-	-	F	-	-	-	Phosphorylase superfamily
NPEPPOKF_01734	2.92e-38	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
NPEPPOKF_01735	1.72e-142	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
NPEPPOKF_01736	1.27e-98	-	-	-	K	-	-	-	Transcriptional regulator
NPEPPOKF_01737	3.99e-96	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
NPEPPOKF_01738	5.51e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
NPEPPOKF_01739	5.38e-290	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
NPEPPOKF_01740	3.98e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
NPEPPOKF_01741	2.79e-274	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
NPEPPOKF_01743	2.16e-204	morA	-	-	S	-	-	-	reductase
NPEPPOKF_01744	8.21e-213	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo keto reductase
NPEPPOKF_01745	1.92e-106	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase like
NPEPPOKF_01746	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
NPEPPOKF_01747	7.45e-103	-	-	-	-	-	-	-	-
NPEPPOKF_01748	0.0	-	-	-	-	-	-	-	-
NPEPPOKF_01749	6.49e-268	-	-	-	C	-	-	-	Oxidoreductase
NPEPPOKF_01750	3.28e-193	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
NPEPPOKF_01751	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NPEPPOKF_01752	2.57e-128	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
NPEPPOKF_01754	4.37e-167	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
NPEPPOKF_01755	4.14e-72	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
NPEPPOKF_01756	2.09e-171	-	-	-	-	-	-	-	-
NPEPPOKF_01757	1.57e-191	-	-	-	-	-	-	-	-
NPEPPOKF_01758	3.37e-115	-	-	-	-	-	-	-	-
NPEPPOKF_01759	1.01e-184	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
NPEPPOKF_01760	6.03e-218	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NPEPPOKF_01761	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
NPEPPOKF_01762	8.03e-151	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
NPEPPOKF_01763	0.0	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
NPEPPOKF_01764	9.67e-98	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
NPEPPOKF_01766	5.29e-121	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NPEPPOKF_01767	2.35e-243	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
NPEPPOKF_01768	3.05e-236	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
NPEPPOKF_01769	7.88e-131	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
NPEPPOKF_01770	6.76e-75	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
NPEPPOKF_01771	2.32e-171	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
NPEPPOKF_01772	2.65e-245	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
NPEPPOKF_01773	1.83e-231	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
NPEPPOKF_01774	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
NPEPPOKF_01775	4.15e-191	yxeH	-	-	S	-	-	-	hydrolase
NPEPPOKF_01776	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
NPEPPOKF_01777	1.14e-202	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
NPEPPOKF_01778	2.87e-101	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
NPEPPOKF_01779	2.96e-89	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NPEPPOKF_01780	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NPEPPOKF_01781	5.84e-312	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NPEPPOKF_01782	2.28e-290	sdaC	-	-	E	ko:K03837	-	ko00000,ko02000	amino acid
NPEPPOKF_01783	7.51e-159	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
NPEPPOKF_01784	2.81e-202	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NPEPPOKF_01785	6.59e-170	-	-	-	S	-	-	-	YheO-like PAS domain
NPEPPOKF_01786	4.01e-36	-	-	-	-	-	-	-	-
NPEPPOKF_01787	2.08e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NPEPPOKF_01788	1.26e-305	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NPEPPOKF_01789	1.91e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
NPEPPOKF_01790	2.57e-274	-	-	-	J	-	-	-	translation release factor activity
NPEPPOKF_01791	3.14e-164	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
NPEPPOKF_01792	5.35e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
NPEPPOKF_01793	1.6e-194	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
NPEPPOKF_01794	1.84e-189	-	-	-	-	-	-	-	-
NPEPPOKF_01795	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NPEPPOKF_01796	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NPEPPOKF_01797	9.32e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NPEPPOKF_01798	4.79e-273	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NPEPPOKF_01799	2.58e-85	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
NPEPPOKF_01800	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
NPEPPOKF_01801	1.37e-248	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	ABC transporter, substratebinding protein
NPEPPOKF_01802	3.03e-202	-	-	-	U	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NPEPPOKF_01803	5.79e-171	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NPEPPOKF_01804	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
NPEPPOKF_01805	7.48e-260	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
NPEPPOKF_01806	8.87e-245	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NPEPPOKF_01807	2.29e-292	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NPEPPOKF_01808	2.36e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
NPEPPOKF_01809	3.52e-273	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
NPEPPOKF_01810	1.52e-240	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NPEPPOKF_01811	1.3e-110	queT	-	-	S	-	-	-	QueT transporter
NPEPPOKF_01812	1.4e-147	-	-	-	S	-	-	-	(CBS) domain
NPEPPOKF_01813	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
NPEPPOKF_01814	2.79e-226	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NPEPPOKF_01815	1.43e-129	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NPEPPOKF_01816	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NPEPPOKF_01817	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
NPEPPOKF_01818	7.72e-57	yabO	-	-	J	-	-	-	S4 domain protein
NPEPPOKF_01820	2.02e-83	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
NPEPPOKF_01821	1.07e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
NPEPPOKF_01822	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NPEPPOKF_01823	4.3e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
NPEPPOKF_01824	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NPEPPOKF_01825	1.93e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NPEPPOKF_01826	5.33e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NPEPPOKF_01827	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
NPEPPOKF_01828	1.97e-110	-	-	-	S	-	-	-	Pfam:DUF3816
NPEPPOKF_01829	1.21e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NPEPPOKF_01830	1.27e-143	-	-	-	-	-	-	-	-
NPEPPOKF_01831	1.08e-229	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
NPEPPOKF_01832	3.84e-185	-	-	-	S	-	-	-	Peptidase_C39 like family
NPEPPOKF_01833	1.04e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
NPEPPOKF_01834	3.38e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
NPEPPOKF_01835	9.38e-189	-	-	-	KT	-	-	-	helix_turn_helix, mercury resistance
NPEPPOKF_01836	3.41e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NPEPPOKF_01837	1.86e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
NPEPPOKF_01838	1.2e-240	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
NPEPPOKF_01839	1.18e-155	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPPOKF_01840	2.76e-117	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
NPEPPOKF_01841	5.72e-238	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
NPEPPOKF_01842	3.55e-127	ywjB	-	-	H	-	-	-	RibD C-terminal domain
NPEPPOKF_01843	9.35e-257	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NPEPPOKF_01844	7.1e-152	-	-	-	S	-	-	-	Membrane
NPEPPOKF_01845	2.11e-199	mleP3	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
NPEPPOKF_01846	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
NPEPPOKF_01847	4.32e-261	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NPEPPOKF_01848	7.22e-163	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
NPEPPOKF_01849	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
NPEPPOKF_01850	4.03e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
NPEPPOKF_01851	8.99e-133	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
NPEPPOKF_01852	2.17e-222	-	-	-	S	-	-	-	Conserved hypothetical protein 698
NPEPPOKF_01853	5.9e-194	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
NPEPPOKF_01854	0.0	tagE5	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
NPEPPOKF_01855	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
NPEPPOKF_01857	2.24e-78	-	-	-	M	-	-	-	LysM domain
NPEPPOKF_01858	6.5e-119	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
NPEPPOKF_01859	1.65e-212	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPPOKF_01860	3.91e-269	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NPEPPOKF_01861	6.27e-166	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
NPEPPOKF_01862	4.72e-72	cmd	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
NPEPPOKF_01863	4.77e-100	yphH	-	-	S	-	-	-	Cupin domain
NPEPPOKF_01864	5.19e-103	-	-	-	K	-	-	-	transcriptional regulator, MerR family
NPEPPOKF_01865	4.87e-298	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
NPEPPOKF_01866	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
NPEPPOKF_01867	1.74e-156	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPPOKF_01869	1.19e-150	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NPEPPOKF_01870	3.18e-141	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
NPEPPOKF_01871	1.03e-150	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NPEPPOKF_01873	4.86e-111	-	-	-	-	-	-	-	-
NPEPPOKF_01874	1.04e-110	yvbK	-	-	K	-	-	-	GNAT family
NPEPPOKF_01875	9.76e-50	-	-	-	-	-	-	-	-
NPEPPOKF_01876	2.81e-64	-	-	-	-	-	-	-	-
NPEPPOKF_01877	7.44e-143	pgm8	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
NPEPPOKF_01878	6.09e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
NPEPPOKF_01879	1.51e-200	-	-	-	K	-	-	-	LysR substrate binding domain
NPEPPOKF_01880	1.52e-135	-	-	-	GM	-	-	-	NAD(P)H-binding
NPEPPOKF_01881	1.66e-247	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
NPEPPOKF_01882	2.9e-194	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
NPEPPOKF_01883	1.28e-45	-	-	-	-	-	-	-	-
NPEPPOKF_01884	2.1e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
NPEPPOKF_01885	2.09e-124	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
NPEPPOKF_01886	1.76e-162	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
NPEPPOKF_01887	1.03e-40	-	-	-	-	-	-	-	-
NPEPPOKF_01888	0.0	-	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
NPEPPOKF_01889	0.0	cadA	-	-	P	-	-	-	P-type ATPase
NPEPPOKF_01891	9.45e-160	-	-	-	S	-	-	-	YjbR
NPEPPOKF_01892	4.04e-37	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
NPEPPOKF_01893	3.23e-215	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
NPEPPOKF_01894	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NPEPPOKF_01895	1.44e-255	glmS2	-	-	M	-	-	-	SIS domain
NPEPPOKF_01896	2.07e-35	-	-	-	S	-	-	-	Belongs to the LOG family
NPEPPOKF_01897	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
NPEPPOKF_01898	3.98e-315	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
NPEPPOKF_01899	5.85e-92	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NPEPPOKF_01900	5.38e-92	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NPEPPOKF_01901	4.75e-112	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
NPEPPOKF_01902	1.07e-206	-	-	-	GM	-	-	-	NmrA-like family
NPEPPOKF_01903	2.14e-86	-	-	-	K	ko:K22296	-	ko00000,ko03000	Winged helix DNA-binding domain
NPEPPOKF_01904	9.97e-94	spxA	-	-	P	ko:K16509	-	ko00000	ArsC family
NPEPPOKF_01905	3.46e-87	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
NPEPPOKF_01906	1.7e-70	-	-	-	-	-	-	-	-
NPEPPOKF_01907	4.98e-275	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
NPEPPOKF_01908	2.11e-82	-	-	-	-	-	-	-	-
NPEPPOKF_01909	1.36e-112	-	-	-	-	-	-	-	-
NPEPPOKF_01910	4.58e-103	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
NPEPPOKF_01911	3.78e-73	-	-	-	-	-	-	-	-
NPEPPOKF_01912	4.79e-21	-	-	-	-	-	-	-	-
NPEPPOKF_01913	3.57e-150	-	-	-	GM	-	-	-	NmrA-like family
NPEPPOKF_01914	2.52e-107	-	-	-	S	ko:K02348	-	ko00000	GNAT family
NPEPPOKF_01915	9.43e-203	-	-	-	EG	-	-	-	EamA-like transporter family
NPEPPOKF_01916	2.66e-155	-	-	-	S	-	-	-	membrane
NPEPPOKF_01917	1.47e-144	-	-	-	S	-	-	-	VIT family
NPEPPOKF_01918	4.38e-243	pva2	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
NPEPPOKF_01919	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
NPEPPOKF_01920	8.01e-97	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
NPEPPOKF_01921	4.26e-54	-	-	-	-	-	-	-	-
NPEPPOKF_01922	3.43e-96	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
NPEPPOKF_01923	8.8e-315	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
NPEPPOKF_01924	7.21e-35	-	-	-	-	-	-	-	-
NPEPPOKF_01925	2.55e-65	-	-	-	-	-	-	-	-
NPEPPOKF_01926	2.51e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF1398)
NPEPPOKF_01927	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
NPEPPOKF_01928	1.77e-282	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
NPEPPOKF_01929	9.92e-230	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
NPEPPOKF_01930	6.1e-101	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
NPEPPOKF_01931	1.14e-110	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
NPEPPOKF_01932	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
NPEPPOKF_01933	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
NPEPPOKF_01934	2.3e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
NPEPPOKF_01935	1.36e-209	yvgN	-	-	C	-	-	-	Aldo keto reductase
NPEPPOKF_01936	2.57e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
NPEPPOKF_01937	1.7e-101	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
NPEPPOKF_01938	1.5e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
NPEPPOKF_01939	2.69e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NPEPPOKF_01940	5.94e-118	ymdB	-	-	S	-	-	-	Macro domain protein
NPEPPOKF_01941	6.47e-124	-	-	-	K	ko:K22041	-	ko00000,ko03000	transcriptional regulator
NPEPPOKF_01942	1.58e-66	-	-	-	-	-	-	-	-
NPEPPOKF_01943	2.41e-212	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
NPEPPOKF_01944	0.0	-	-	-	-	-	-	-	-
NPEPPOKF_01945	2.08e-161	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
NPEPPOKF_01946	3.5e-205	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NPEPPOKF_01947	2.97e-244	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
NPEPPOKF_01948	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
NPEPPOKF_01949	1.55e-230	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
NPEPPOKF_01950	5.55e-100	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
NPEPPOKF_01951	6.61e-29	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
NPEPPOKF_01952	1.11e-33	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
NPEPPOKF_01953	3.38e-50	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
NPEPPOKF_01954	1.29e-235	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
NPEPPOKF_01955	5.91e-297	-	-	-	P	ko:K06610	-	ko00000,ko02000	Major Facilitator Superfamily
NPEPPOKF_01956	0.0	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
NPEPPOKF_01957	2.9e-293	-	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
NPEPPOKF_01958	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
NPEPPOKF_01959	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
NPEPPOKF_01960	1.95e-140	aqpZ	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
NPEPPOKF_01961	3.7e-279	-	-	-	S	-	-	-	associated with various cellular activities
NPEPPOKF_01962	9.34e-317	-	-	-	S	-	-	-	Putative metallopeptidase domain
NPEPPOKF_01963	1.03e-65	-	-	-	-	-	-	-	-
NPEPPOKF_01964	8.19e-134	yezE	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
NPEPPOKF_01965	7.83e-60	-	-	-	-	-	-	-	-
NPEPPOKF_01966	4.23e-129	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
NPEPPOKF_01967	8.67e-160	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
NPEPPOKF_01968	1.83e-235	-	-	-	S	-	-	-	Cell surface protein
NPEPPOKF_01969	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
NPEPPOKF_01970	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
NPEPPOKF_01971	1.06e-106	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NPEPPOKF_01972	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
NPEPPOKF_01973	1.82e-152	rcfA	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
NPEPPOKF_01974	2.98e-44	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
NPEPPOKF_01975	4.27e-126	dpsB	-	-	P	-	-	-	Belongs to the Dps family
NPEPPOKF_01976	1.01e-26	-	-	-	-	-	-	-	-
NPEPPOKF_01977	4.82e-55	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
NPEPPOKF_01978	5.73e-73	trxA3	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
NPEPPOKF_01979	9.44e-183	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
NPEPPOKF_01980	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
NPEPPOKF_01981	8.06e-232	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
NPEPPOKF_01982	1.5e-165	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
NPEPPOKF_01983	4.16e-175	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NPEPPOKF_01984	4.84e-230	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
NPEPPOKF_01985	1.12e-134	-	-	-	K	-	-	-	transcriptional regulator
NPEPPOKF_01987	9.39e-84	-	-	-	-	-	-	-	-
NPEPPOKF_01989	5.77e-81	-	-	-	-	-	-	-	-
NPEPPOKF_01990	6.18e-71	-	-	-	-	-	-	-	-
NPEPPOKF_01991	1.88e-96	-	-	-	M	-	-	-	PFAM NLP P60 protein
NPEPPOKF_01992	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
NPEPPOKF_01993	4.45e-38	-	-	-	-	-	-	-	-
NPEPPOKF_01994	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
NPEPPOKF_01995	3.81e-150	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NPEPPOKF_01996	3.08e-113	-	-	-	K	-	-	-	Winged helix DNA-binding domain
NPEPPOKF_01997	1.63e-176	yesN	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
NPEPPOKF_01998	3.17e-170	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
NPEPPOKF_01999	1.56e-71	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
NPEPPOKF_02000	2.56e-131	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
NPEPPOKF_02001	8.07e-163	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
NPEPPOKF_02002	6.36e-134	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NPEPPOKF_02003	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
NPEPPOKF_02004	1.56e-108	-	-	-	-	-	-	-	-
NPEPPOKF_02005	5.97e-96	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
NPEPPOKF_02006	9.2e-243	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NPEPPOKF_02007	7.3e-245	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NPEPPOKF_02008	3.7e-30	-	-	-	-	-	-	-	-
NPEPPOKF_02009	1.38e-131	-	-	-	-	-	-	-	-
NPEPPOKF_02010	3.46e-210	-	-	-	K	-	-	-	LysR substrate binding domain
NPEPPOKF_02011	4.34e-314	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
NPEPPOKF_02012	0.0	-	4.1.1.98	-	H	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
NPEPPOKF_02013	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
NPEPPOKF_02014	1.37e-182	-	-	-	S	-	-	-	zinc-ribbon domain
NPEPPOKF_02016	4.29e-50	-	-	-	-	-	-	-	-
NPEPPOKF_02017	1.4e-137	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
NPEPPOKF_02018	1.4e-20	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
NPEPPOKF_02019	2.35e-231	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
NPEPPOKF_02020	0.0	-	-	-	I	-	-	-	acetylesterase activity
NPEPPOKF_02021	6.08e-78	-	-	-	M	-	-	-	Collagen binding domain
NPEPPOKF_02022	6.92e-206	yicL	-	-	EG	-	-	-	EamA-like transporter family
NPEPPOKF_02023	6.12e-166	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
NPEPPOKF_02024	3.39e-225	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
NPEPPOKF_02025	5.93e-144	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
NPEPPOKF_02026	5.07e-62	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
NPEPPOKF_02027	3.06e-206	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
NPEPPOKF_02028	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
NPEPPOKF_02029	9.86e-117	-	-	-	-	-	-	-	-
NPEPPOKF_02030	1.02e-164	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
NPEPPOKF_02031	9.21e-234	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
NPEPPOKF_02032	7.39e-121	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
NPEPPOKF_02033	5.85e-204	ccpB	-	-	K	-	-	-	lacI family
NPEPPOKF_02034	2.21e-154	yceE	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
NPEPPOKF_02035	8.08e-154	ydgI3	-	-	C	-	-	-	Nitroreductase family
NPEPPOKF_02036	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
NPEPPOKF_02037	4.21e-150	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NPEPPOKF_02038	5.82e-198	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NPEPPOKF_02039	6.97e-216	XK27_00670	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
NPEPPOKF_02040	0.0	-	-	-	-	-	-	-	-
NPEPPOKF_02041	4.71e-81	-	-	-	-	-	-	-	-
NPEPPOKF_02042	5.52e-242	-	-	-	S	-	-	-	Cell surface protein
NPEPPOKF_02043	1.27e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
NPEPPOKF_02044	5.06e-82	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
NPEPPOKF_02045	3.13e-42	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
NPEPPOKF_02046	2.78e-158	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
NPEPPOKF_02047	5.21e-180	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
NPEPPOKF_02048	2.29e-193	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
NPEPPOKF_02049	4.54e-191	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
NPEPPOKF_02050	1.04e-269	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
NPEPPOKF_02052	1.15e-43	-	-	-	-	-	-	-	-
NPEPPOKF_02053	4.84e-227	-	-	-	-	-	-	-	-
NPEPPOKF_02054	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
NPEPPOKF_02055	7.1e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
NPEPPOKF_02056	2.64e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
NPEPPOKF_02057	2.15e-209	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
NPEPPOKF_02058	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
NPEPPOKF_02059	2.36e-285	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NPEPPOKF_02060	8.65e-228	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
NPEPPOKF_02061	1.21e-268	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
NPEPPOKF_02062	3.95e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NPEPPOKF_02063	6.45e-111	-	-	-	-	-	-	-	-
NPEPPOKF_02064	4.86e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
NPEPPOKF_02065	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NPEPPOKF_02066	3.45e-240	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
NPEPPOKF_02067	2.16e-39	-	-	-	-	-	-	-	-
NPEPPOKF_02068	2.62e-168	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
NPEPPOKF_02069	5.35e-220	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NPEPPOKF_02070	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NPEPPOKF_02071	1.02e-155	-	-	-	S	-	-	-	repeat protein
NPEPPOKF_02072	2.41e-157	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
NPEPPOKF_02073	0.0	-	-	-	N	-	-	-	domain, Protein
NPEPPOKF_02074	2.02e-247	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
NPEPPOKF_02075	4.17e-153	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
NPEPPOKF_02076	4.64e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
NPEPPOKF_02077	9.64e-307	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
NPEPPOKF_02078	1.53e-284	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NPEPPOKF_02079	4.94e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
NPEPPOKF_02080	8.09e-275	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
NPEPPOKF_02081	5.85e-158	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NPEPPOKF_02082	7.74e-47	-	-	-	-	-	-	-	-
NPEPPOKF_02083	3.51e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
NPEPPOKF_02084	3.46e-242	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NPEPPOKF_02085	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NPEPPOKF_02086	6.52e-124	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
NPEPPOKF_02087	2.06e-187	ylmH	-	-	S	-	-	-	S4 domain protein
NPEPPOKF_02088	6.45e-49	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
NPEPPOKF_02089	1.56e-93	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NPEPPOKF_02090	9.39e-295	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NPEPPOKF_02091	3.55e-312	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NPEPPOKF_02092	2.34e-208	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NPEPPOKF_02093	2.04e-252	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NPEPPOKF_02094	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NPEPPOKF_02095	2.81e-231	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NPEPPOKF_02096	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
NPEPPOKF_02097	7.01e-76	ftsL	-	-	D	-	-	-	Cell division protein FtsL
NPEPPOKF_02098	1.74e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NPEPPOKF_02099	7.24e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
NPEPPOKF_02100	3.22e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
NPEPPOKF_02101	4.1e-223	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
NPEPPOKF_02102	4.08e-101	-	-	-	K	-	-	-	MerR family regulatory protein
NPEPPOKF_02103	7.54e-200	-	-	-	GM	-	-	-	NmrA-like family
NPEPPOKF_02104	0.0	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NPEPPOKF_02105	1.25e-164	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
NPEPPOKF_02107	2.95e-100	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
NPEPPOKF_02108	8.44e-304	-	-	-	S	-	-	-	module of peptide synthetase
NPEPPOKF_02109	1.16e-135	-	-	-	-	-	-	-	-
NPEPPOKF_02110	1.55e-114	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
NPEPPOKF_02111	1.28e-77	-	-	-	S	-	-	-	Enterocin A Immunity
NPEPPOKF_02112	6.46e-49	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
NPEPPOKF_02113	7.47e-77	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
NPEPPOKF_02114	1.33e-100	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
NPEPPOKF_02115	2.8e-135	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NPEPPOKF_02116	4.14e-84	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
NPEPPOKF_02117	2.88e-164	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
NPEPPOKF_02118	1.56e-185	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
NPEPPOKF_02119	1.03e-34	-	-	-	-	-	-	-	-
NPEPPOKF_02120	7.02e-151	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
NPEPPOKF_02121	0.0	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
NPEPPOKF_02122	2.85e-210	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
NPEPPOKF_02123	9.07e-233	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
NPEPPOKF_02124	1.49e-253	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
NPEPPOKF_02125	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
NPEPPOKF_02126	2.05e-72	-	-	-	S	-	-	-	Enterocin A Immunity
NPEPPOKF_02127	3.66e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NPEPPOKF_02128	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NPEPPOKF_02129	4.17e-235	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NPEPPOKF_02130	1.02e-187	ptp2	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
NPEPPOKF_02131	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPEPPOKF_02133	4.62e-107	-	-	-	-	-	-	-	-
NPEPPOKF_02134	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
NPEPPOKF_02136	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
NPEPPOKF_02137	1.07e-211	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NPEPPOKF_02138	3.1e-228	ydbI	-	-	K	-	-	-	AI-2E family transporter
NPEPPOKF_02139	1.38e-275	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
NPEPPOKF_02140	1.63e-77	-	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
NPEPPOKF_02141	1.97e-60	qacH	-	-	U	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
NPEPPOKF_02142	2.94e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
NPEPPOKF_02143	7.27e-73	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
NPEPPOKF_02144	1.3e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
NPEPPOKF_02145	8.03e-28	-	-	-	-	-	-	-	-
NPEPPOKF_02146	3.91e-124	tag2	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
NPEPPOKF_02147	5.59e-271	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
NPEPPOKF_02148	2.01e-134	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
NPEPPOKF_02149	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
NPEPPOKF_02150	1.8e-134	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
NPEPPOKF_02151	1.59e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
NPEPPOKF_02152	9.61e-84	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NPEPPOKF_02153	4.26e-109	cvpA	-	-	S	-	-	-	Colicin V production protein
NPEPPOKF_02154	5.61e-216	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
NPEPPOKF_02155	8.83e-317	-	-	-	EGP	-	-	-	Major Facilitator
NPEPPOKF_02157	4.54e-54	-	-	-	-	-	-	-	-
NPEPPOKF_02158	2.81e-167	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
NPEPPOKF_02159	2.88e-106	gtcA3	-	-	S	-	-	-	GtrA-like protein
NPEPPOKF_02160	3.35e-157	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NPEPPOKF_02161	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
NPEPPOKF_02162	1.18e-94	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
NPEPPOKF_02163	7.03e-62	-	-	-	-	-	-	-	-
NPEPPOKF_02164	1.81e-150	-	-	-	S	-	-	-	SNARE associated Golgi protein
NPEPPOKF_02165	8.58e-65	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
NPEPPOKF_02166	7.89e-124	-	-	-	P	-	-	-	Cadmium resistance transporter
NPEPPOKF_02167	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPPOKF_02168	3.93e-38	-	-	-	P	-	-	-	Concanavalin A-like lectin/glucanases superfamily
NPEPPOKF_02170	2.03e-84	-	-	-	-	-	-	-	-
NPEPPOKF_02171	1.58e-204	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
NPEPPOKF_02172	1.21e-73	-	-	-	-	-	-	-	-
NPEPPOKF_02173	1.24e-194	-	-	-	K	-	-	-	Helix-turn-helix domain
NPEPPOKF_02174	3.91e-100	pts23A	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NPEPPOKF_02175	7.47e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NPEPPOKF_02176	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPEPPOKF_02177	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NPEPPOKF_02178	4.32e-235	-	-	-	GM	-	-	-	Male sterility protein
NPEPPOKF_02179	2.1e-99	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NPEPPOKF_02180	4.61e-101	-	-	-	M	-	-	-	LysM domain
NPEPPOKF_02181	7.94e-126	-	-	-	M	-	-	-	Lysin motif
NPEPPOKF_02182	5.71e-138	-	-	-	S	-	-	-	SdpI/YhfL protein family
NPEPPOKF_02183	1.58e-72	nudA	-	-	S	-	-	-	ASCH
NPEPPOKF_02184	5.76e-212	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
NPEPPOKF_02185	3.57e-120	-	-	-	-	-	-	-	-
NPEPPOKF_02186	1.92e-155	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
NPEPPOKF_02187	3.55e-281	-	-	-	T	-	-	-	diguanylate cyclase
NPEPPOKF_02188	7.43e-97	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
NPEPPOKF_02189	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
NPEPPOKF_02190	2.31e-277	-	-	-	-	-	-	-	-
NPEPPOKF_02191	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NPEPPOKF_02192	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPPOKF_02194	3.23e-290	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
NPEPPOKF_02195	2.96e-209	yhxD	-	-	IQ	-	-	-	KR domain
NPEPPOKF_02197	1.97e-92	-	-	-	-	-	-	-	-
NPEPPOKF_02198	1.43e-184	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NPEPPOKF_02199	0.0	-	-	-	E	-	-	-	Amino Acid
NPEPPOKF_02200	4.8e-86	lysM	-	-	M	-	-	-	LysM domain
NPEPPOKF_02201	4.2e-286	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
NPEPPOKF_02202	6.8e-272	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
NPEPPOKF_02203	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
NPEPPOKF_02204	1.23e-57	-	-	-	S	-	-	-	Cupredoxin-like domain
NPEPPOKF_02205	1.36e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
NPEPPOKF_02206	2.69e-316	dinF	-	-	V	-	-	-	MatE
NPEPPOKF_02207	1.79e-42	-	-	-	-	-	-	-	-
NPEPPOKF_02209	8.2e-102	yybD	-	-	S	ko:K02348	-	ko00000	Acetyltransferase (GNAT) domain
NPEPPOKF_02210	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
NPEPPOKF_02211	4.64e-106	-	-	-	-	-	-	-	-
NPEPPOKF_02212	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
NPEPPOKF_02213	1.04e-136	-	-	-	-	-	-	-	-
NPEPPOKF_02214	0.0	celR	-	-	K	-	-	-	PRD domain
NPEPPOKF_02215	1.34e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
NPEPPOKF_02216	2.37e-68	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
NPEPPOKF_02217	4.9e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NPEPPOKF_02218	1.71e-277	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPEPPOKF_02219	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NPEPPOKF_02220	3.5e-271	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
NPEPPOKF_02221	2.34e-146	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
NPEPPOKF_02222	1.65e-46	dltC2	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPEPPOKF_02223	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	Alanine-glyoxylate amino-transferase
NPEPPOKF_02224	8.08e-133	argO	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
NPEPPOKF_02225	5.58e-271	arcT	-	-	E	-	-	-	Aminotransferase
NPEPPOKF_02226	2.07e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NPEPPOKF_02227	2.43e-18	-	-	-	-	-	-	-	-
NPEPPOKF_02228	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
NPEPPOKF_02229	9.94e-71	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
NPEPPOKF_02230	4.47e-296	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
NPEPPOKF_02231	0.0	yhaN	-	-	L	-	-	-	AAA domain
NPEPPOKF_02232	1.03e-240	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
NPEPPOKF_02233	1.05e-272	-	-	-	-	-	-	-	-
NPEPPOKF_02234	2.41e-233	-	-	-	M	-	-	-	Peptidase family S41
NPEPPOKF_02235	1.09e-225	-	-	-	K	-	-	-	LysR substrate binding domain
NPEPPOKF_02236	9.9e-144	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
NPEPPOKF_02237	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
NPEPPOKF_02238	4.43e-129	-	-	-	-	-	-	-	-
NPEPPOKF_02239	1.17e-100	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
NPEPPOKF_02240	1.15e-235	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
NPEPPOKF_02241	7.78e-20	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NPEPPOKF_02242	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NPEPPOKF_02243	4.29e-26	-	-	-	S	-	-	-	NUDIX domain
NPEPPOKF_02244	0.0	-	-	-	S	-	-	-	membrane
NPEPPOKF_02245	4.26e-218	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NPEPPOKF_02246	2.61e-95	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
NPEPPOKF_02247	2.08e-284	ribA	3.5.4.25, 4.1.99.12	-	H	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
NPEPPOKF_02248	1.23e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NPEPPOKF_02249	5.21e-137	-	-	-	S	ko:K09962	-	ko00000	Nucleotidyltransferase
NPEPPOKF_02250	1.96e-137	-	-	-	-	-	-	-	-
NPEPPOKF_02251	3.3e-151	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
NPEPPOKF_02252	1.08e-95	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NPEPPOKF_02253	1.75e-47	-	-	-	K	-	-	-	MerR HTH family regulatory protein
NPEPPOKF_02254	2.03e-155	azlC	-	-	E	-	-	-	branched-chain amino acid
NPEPPOKF_02255	3.43e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
NPEPPOKF_02256	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
NPEPPOKF_02257	9.85e-281	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
NPEPPOKF_02258	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NPEPPOKF_02259	0.0	xylP2	-	-	G	-	-	-	symporter
NPEPPOKF_02260	4.24e-246	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NPEPPOKF_02261	3.33e-64	-	-	-	-	-	-	-	-
NPEPPOKF_02262	1.24e-155	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
NPEPPOKF_02263	7.84e-117	-	-	-	K	-	-	-	FR47-like protein
NPEPPOKF_02264	4.18e-163	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
NPEPPOKF_02265	1.89e-277	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
NPEPPOKF_02266	2.26e-243	-	-	-	-	-	-	-	-
NPEPPOKF_02267	2.91e-179	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
NPEPPOKF_02268	5.06e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
NPEPPOKF_02269	9.95e-211	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NPEPPOKF_02270	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
NPEPPOKF_02271	4.95e-44	-	-	-	L	-	-	-	leucine-zipper of insertion element IS481
NPEPPOKF_02272	9.05e-55	-	-	-	-	-	-	-	-
NPEPPOKF_02273	1.32e-290	-	-	-	L	-	-	-	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NPEPPOKF_02274	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NPEPPOKF_02275	3.39e-255	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
NPEPPOKF_02276	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
NPEPPOKF_02277	1.64e-149	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NPEPPOKF_02278	4.3e-106	-	-	-	K	-	-	-	Transcriptional regulator
NPEPPOKF_02280	5.68e-266	-	-	-	C	-	-	-	FMN_bind
NPEPPOKF_02281	4.37e-120	-	-	-	C	-	-	-	FMN_bind
NPEPPOKF_02282	3.93e-220	-	-	-	K	-	-	-	Transcriptional regulator
NPEPPOKF_02283	7.39e-54	-	-	-	K	-	-	-	Helix-turn-helix domain
NPEPPOKF_02284	2.56e-60	-	-	-	K	-	-	-	Helix-turn-helix domain
NPEPPOKF_02285	7.45e-180	-	-	-	K	-	-	-	sequence-specific DNA binding
NPEPPOKF_02286	1.73e-113	-	-	-	S	-	-	-	AAA domain
NPEPPOKF_02287	1.42e-08	-	-	-	-	-	-	-	-
NPEPPOKF_02288	5.1e-315	-	-	-	M	-	-	-	MucBP domain
NPEPPOKF_02289	0.0	-	-	-	M	-	-	-	MucBP domain
NPEPPOKF_02290	4.85e-119	XK27_09665	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
NPEPPOKF_02291	3.79e-57	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
NPEPPOKF_02292	4.61e-222	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NPEPPOKF_02293	5.09e-81	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
NPEPPOKF_02294	9.16e-190	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
NPEPPOKF_02295	2.92e-118	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
NPEPPOKF_02296	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
NPEPPOKF_02297	3.73e-131	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
NPEPPOKF_02298	2.33e-283	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
NPEPPOKF_02299	1.07e-131	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
NPEPPOKF_02300	1.8e-249	-	-	-	C	-	-	-	Aldo/keto reductase family
NPEPPOKF_02302	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NPEPPOKF_02303	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NPEPPOKF_02304	6.27e-316	-	-	-	EGP	-	-	-	Major Facilitator
NPEPPOKF_02309	2.06e-313	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
NPEPPOKF_02310	1.23e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
NPEPPOKF_02311	6.88e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
NPEPPOKF_02312	4.36e-197	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
NPEPPOKF_02313	1.39e-134	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NPEPPOKF_02314	8.76e-126	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
NPEPPOKF_02315	2.09e-287	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NPEPPOKF_02316	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
NPEPPOKF_02317	5.69e-191	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
NPEPPOKF_02318	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
NPEPPOKF_02319	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
NPEPPOKF_02320	1.35e-264	-	-	-	EGP	-	-	-	Major facilitator Superfamily
NPEPPOKF_02321	1.54e-219	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NPEPPOKF_02322	1.76e-298	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
NPEPPOKF_02323	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
NPEPPOKF_02324	9.55e-205	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NPEPPOKF_02325	1.01e-167	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
NPEPPOKF_02326	0.0	-	-	-	-	-	-	-	-
NPEPPOKF_02327	2e-52	-	-	-	S	-	-	-	Cytochrome B5
NPEPPOKF_02328	8.68e-118	pts21A	-	-	G	ko:K02755	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NPEPPOKF_02329	6.48e-135	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
NPEPPOKF_02330	1.91e-165	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NPEPPOKF_02331	1.22e-226	-	-	-	EG	-	-	-	EamA-like transporter family
NPEPPOKF_02332	3.06e-214	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
NPEPPOKF_02333	5.37e-233	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
NPEPPOKF_02334	1.05e-172	accA1	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
NPEPPOKF_02335	1.49e-183	accD1	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NPEPPOKF_02336	1.7e-315	accC1	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
NPEPPOKF_02337	9.24e-85	accB1	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin-requiring enzyme
NPEPPOKF_02338	3.15e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NPEPPOKF_02339	4.5e-113	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
NPEPPOKF_02340	4.16e-93	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
NPEPPOKF_02341	0.0	levR	-	-	K	-	-	-	Sigma-54 interaction domain
NPEPPOKF_02342	9.05e-85	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
NPEPPOKF_02343	4.22e-216	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
NPEPPOKF_02344	4.51e-172	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
NPEPPOKF_02345	6.46e-218	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
NPEPPOKF_02346	1.53e-195	-	-	-	G	-	-	-	Peptidase_C39 like family
NPEPPOKF_02348	1.9e-198	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NPEPPOKF_02349	1.71e-302	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
NPEPPOKF_02350	3.09e-106	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
NPEPPOKF_02351	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
NPEPPOKF_02352	2.57e-94	-	-	-	-	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	-
NPEPPOKF_02353	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
NPEPPOKF_02354	1.51e-196	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NPEPPOKF_02355	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NPEPPOKF_02356	5.44e-175	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NPEPPOKF_02357	5.41e-160	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
NPEPPOKF_02358	2.92e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NPEPPOKF_02359	2.18e-174	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NPEPPOKF_02360	1.06e-195	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
NPEPPOKF_02361	1.59e-247	ysdE	-	-	P	-	-	-	Citrate transporter
NPEPPOKF_02362	3.1e-212	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
NPEPPOKF_02363	1.38e-71	-	-	-	S	-	-	-	Cupin domain
NPEPPOKF_02364	9.02e-66	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
NPEPPOKF_02368	1.75e-193	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NPEPPOKF_02369	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
NPEPPOKF_02371	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
NPEPPOKF_02372	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
NPEPPOKF_02373	1.08e-221	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
NPEPPOKF_02374	0.0	treP	2.4.1.64	GH65	G	ko:K05342	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
NPEPPOKF_02375	1.3e-203	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
NPEPPOKF_02376	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NPEPPOKF_02377	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NPEPPOKF_02378	2.62e-216	pbg9	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NPEPPOKF_02379	3.72e-200	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
NPEPPOKF_02380	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NPEPPOKF_02381	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NPEPPOKF_02382	2.26e-269	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
NPEPPOKF_02383	6.87e-202	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
NPEPPOKF_02384	1.67e-208	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NPEPPOKF_02385	0.0	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPEPPOKF_02386	5.44e-174	-	-	-	K	-	-	-	UTRA domain
NPEPPOKF_02387	1.78e-198	estA	-	-	S	-	-	-	Putative esterase
NPEPPOKF_02388	2.97e-83	-	-	-	-	-	-	-	-
NPEPPOKF_02389	1.75e-268	-	-	-	G	-	-	-	Major Facilitator Superfamily
NPEPPOKF_02390	5.79e-209	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
NPEPPOKF_02391	1.66e-215	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NPEPPOKF_02392	1.33e-274	-	-	-	G	-	-	-	Transporter
NPEPPOKF_02393	5.56e-167	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NPEPPOKF_02394	1.23e-228	apbE3	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NPEPPOKF_02395	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
NPEPPOKF_02396	2.86e-85	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
NPEPPOKF_02397	1.42e-245	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
NPEPPOKF_02398	3.69e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
NPEPPOKF_02399	3.51e-252	galM3	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
NPEPPOKF_02400	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
NPEPPOKF_02401	6.39e-169	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
NPEPPOKF_02402	8.05e-166	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NPEPPOKF_02403	1.9e-230	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
NPEPPOKF_02404	2.26e-209	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NPEPPOKF_02405	6.87e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
NPEPPOKF_02406	1.19e-201	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NPEPPOKF_02407	1.6e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NPEPPOKF_02408	1.63e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
NPEPPOKF_02410	2.53e-106	mutR	-	-	K	ko:K20373,ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
NPEPPOKF_02411	1.81e-273	-	-	-	EGP	ko:K02030	-	ko00000,ko00002,ko02000	Drug resistance transporter Bcr CflA subfamily
NPEPPOKF_02412	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NPEPPOKF_02413	4.64e-92	-	-	-	F	-	-	-	DNA mismatch repair protein MutT
NPEPPOKF_02414	1.12e-205	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
NPEPPOKF_02415	3.56e-170	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
NPEPPOKF_02416	7.71e-228	-	-	-	-	-	-	-	-
NPEPPOKF_02417	1.37e-290	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
NPEPPOKF_02418	1.36e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
NPEPPOKF_02419	4.87e-243	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NPEPPOKF_02420	1.6e-77	chpA	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
NPEPPOKF_02421	5.9e-46	-	-	-	-	-	-	-	-
NPEPPOKF_02422	1.69e-97	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
NPEPPOKF_02423	9.68e-34	-	-	-	-	-	-	-	-
NPEPPOKF_02424	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPEPPOKF_02425	2.69e-166	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
NPEPPOKF_02426	2.35e-243	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NPEPPOKF_02427	1.38e-179	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
NPEPPOKF_02428	0.0	-	-	-	L	-	-	-	DNA helicase
NPEPPOKF_02429	4.23e-64	axe	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
NPEPPOKF_02430	3.74e-144	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NPEPPOKF_02431	4.56e-144	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
NPEPPOKF_02432	8.02e-152	plnU	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NPEPPOKF_02433	2.6e-140	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NPEPPOKF_02434	1.17e-306	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
NPEPPOKF_02435	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NPEPPOKF_02436	2.59e-19	-	-	-	-	-	-	-	-
NPEPPOKF_02437	1.93e-31	plnF	-	-	-	-	-	-	-
NPEPPOKF_02438	8.15e-167	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NPEPPOKF_02439	2.2e-280	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
NPEPPOKF_02440	5.66e-74	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NPEPPOKF_02441	3.18e-77	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NPEPPOKF_02442	3.81e-18	-	-	-	-	-	-	-	-
NPEPPOKF_02443	1.29e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NPEPPOKF_02444	4.37e-208	fbpA	-	-	K	-	-	-	Domain of unknown function (DUF814)
NPEPPOKF_02445	1.15e-79	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
NPEPPOKF_02446	6.33e-46	-	-	-	-	-	-	-	-
NPEPPOKF_02447	3.38e-227	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
NPEPPOKF_02448	6.7e-148	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
NPEPPOKF_02449	1.24e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NPEPPOKF_02450	1.45e-278	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPEPPOKF_02451	2.65e-102	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
NPEPPOKF_02452	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
NPEPPOKF_02453	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
NPEPPOKF_02454	1.03e-201	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
NPEPPOKF_02456	0.0	-	-	-	M	-	-	-	domain protein
NPEPPOKF_02457	5.44e-35	mleR	-	-	K	-	-	-	LysR substrate binding domain
NPEPPOKF_02458	1.63e-163	mleR	-	-	K	-	-	-	LysR substrate binding domain
NPEPPOKF_02459	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
NPEPPOKF_02460	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
NPEPPOKF_02461	4.71e-210	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
NPEPPOKF_02462	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
NPEPPOKF_02463	3.97e-229	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
NPEPPOKF_02464	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
NPEPPOKF_02465	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NPEPPOKF_02466	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
NPEPPOKF_02467	6.27e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
NPEPPOKF_02468	1.17e-60	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
NPEPPOKF_02469	1.5e-104	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NPEPPOKF_02470	5.55e-22	-	-	-	G	ko:K11203	-	ko00000,ko00002,ko02000	PTS system, fructose subfamily
NPEPPOKF_02471	2.52e-35	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NPEPPOKF_02472	9.49e-155	fptC	-	-	U	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase system, EIIC
NPEPPOKF_02473	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
NPEPPOKF_02474	2.24e-116	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
NPEPPOKF_02475	3.54e-190	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
NPEPPOKF_02476	2.69e-194	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
NPEPPOKF_02477	6.26e-101	-	-	-	-	-	-	-	-
NPEPPOKF_02478	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NPEPPOKF_02479	2.93e-151	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPPOKF_02480	2.44e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
NPEPPOKF_02481	3.73e-263	-	-	-	S	-	-	-	DUF218 domain
NPEPPOKF_02482	1.06e-232	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
NPEPPOKF_02483	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
NPEPPOKF_02484	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NPEPPOKF_02485	1.6e-200	-	-	-	S	-	-	-	Putative adhesin
NPEPPOKF_02486	1.73e-132	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
NPEPPOKF_02487	2.86e-68	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
NPEPPOKF_02488	1.07e-127	-	-	-	KT	-	-	-	response to antibiotic
NPEPPOKF_02489	1.26e-161	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
NPEPPOKF_02490	3.02e-176	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NPEPPOKF_02491	2.11e-158	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NPEPPOKF_02492	2.13e-167	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
NPEPPOKF_02493	2.07e-302	-	-	-	EK	-	-	-	Aminotransferase, class I
NPEPPOKF_02494	3.36e-216	-	-	-	K	-	-	-	LysR substrate binding domain
NPEPPOKF_02495	3.66e-189	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NPEPPOKF_02496	2.89e-312	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
NPEPPOKF_02497	2.1e-116	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
NPEPPOKF_02498	1.06e-16	-	-	-	-	-	-	-	-
NPEPPOKF_02499	1.96e-21	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
NPEPPOKF_02500	0.0	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
NPEPPOKF_02501	1.32e-101	nrp	-	-	K	ko:K16509	-	ko00000	ArsC family
NPEPPOKF_02502	7.42e-174	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
NPEPPOKF_02503	3.78e-212	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
NPEPPOKF_02504	9.62e-19	-	-	-	-	-	-	-	-
NPEPPOKF_02505	1.51e-85	-	-	-	KOT	ko:K07813	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01002	May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
NPEPPOKF_02506	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
NPEPPOKF_02508	8.76e-72	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
NPEPPOKF_02509	6.67e-165	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
NPEPPOKF_02510	0.0	pox4	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
NPEPPOKF_02511	5.03e-95	-	-	-	K	-	-	-	Transcriptional regulator
NPEPPOKF_02512	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
NPEPPOKF_02513	6.96e-83	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
NPEPPOKF_02514	5.88e-233	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
NPEPPOKF_02515	1.23e-129	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
NPEPPOKF_02516	3.33e-113	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
NPEPPOKF_02517	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
NPEPPOKF_02518	1.56e-185	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
NPEPPOKF_02519	2.53e-209	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
NPEPPOKF_02520	2.03e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NPEPPOKF_02521	4.52e-209	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NPEPPOKF_02522	1.88e-240	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NPEPPOKF_02523	3.36e-06	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
NPEPPOKF_02524	2.46e-08	-	-	-	-	-	-	-	-
NPEPPOKF_02525	1.23e-26	-	-	-	-	-	-	-	-
NPEPPOKF_02526	1.1e-147	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
NPEPPOKF_02527	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NPEPPOKF_02528	9.2e-317	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPEPPOKF_02529	2.09e-85	-	-	-	-	-	-	-	-
NPEPPOKF_02530	2.85e-83	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
NPEPPOKF_02531	2.15e-281	-	-	-	S	-	-	-	Membrane
NPEPPOKF_02532	1.04e-59	-	-	-	S	-	-	-	Protein of unknown function (DUF3781)
NPEPPOKF_02533	1.31e-139	yoaZ	-	-	S	-	-	-	intracellular protease amidase
NPEPPOKF_02534	2.33e-56	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
NPEPPOKF_02535	5.36e-76	-	-	-	-	-	-	-	-
NPEPPOKF_02536	1.46e-81	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NPEPPOKF_02537	5.31e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
NPEPPOKF_02538	3.17e-258	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
NPEPPOKF_02539	2e-62	-	-	-	K	-	-	-	Helix-turn-helix domain
NPEPPOKF_02540	3.87e-115	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NPEPPOKF_02541	1.06e-72	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NPEPPOKF_02542	5.53e-114	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPPOKF_02543	6.79e-53	-	-	-	-	-	-	-	-
NPEPPOKF_02544	5.06e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NPEPPOKF_02545	1.6e-233	ydbI	-	-	K	-	-	-	AI-2E family transporter
NPEPPOKF_02546	9.28e-271	xylR	-	-	GK	-	-	-	ROK family
NPEPPOKF_02547	2.92e-143	-	-	-	-	-	-	-	-
NPEPPOKF_02548	3.66e-295	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
NPEPPOKF_02549	3.32e-210	-	-	-	-	-	-	-	-
NPEPPOKF_02550	1.86e-256	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
NPEPPOKF_02551	9.58e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
NPEPPOKF_02552	2.47e-125	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
NPEPPOKF_02553	9.69e-99	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
NPEPPOKF_02554	1.05e-225	hicD1	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
NPEPPOKF_02555	8.95e-60	-	-	-	-	-	-	-	-
NPEPPOKF_02556	1.99e-26	zmp1	-	-	O	-	-	-	Zinc-dependent metalloprotease
NPEPPOKF_02557	8.36e-154	rpiA2	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
NPEPPOKF_02558	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
NPEPPOKF_02559	5.34e-72	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
NPEPPOKF_02560	1.31e-124	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
NPEPPOKF_02561	1.54e-292	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
NPEPPOKF_02562	5.89e-108	-	-	-	K	-	-	-	Winged helix-turn-helix transcription repressor, HrcA DNA-binding
NPEPPOKF_02563	2.16e-103	-	-	-	-	-	-	-	-
NPEPPOKF_02564	2.32e-101	accB3	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NPEPPOKF_02565	1.49e-223	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
NPEPPOKF_02566	2.42e-207	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
NPEPPOKF_02567	4.06e-102	-	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
NPEPPOKF_02568	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NPEPPOKF_02569	2.7e-230	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPPOKF_02570	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
NPEPPOKF_02571	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NPEPPOKF_02572	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
NPEPPOKF_02573	2.14e-174	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
NPEPPOKF_02574	0.0	-	-	-	M	-	-	-	domain protein
NPEPPOKF_02575	6.75e-85	-	-	-	M	-	-	-	dTDP-4-dehydrorhamnose reductase activity
NPEPPOKF_02576	1.82e-34	-	-	-	S	-	-	-	Immunity protein 74
NPEPPOKF_02577	6.57e-226	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
NPEPPOKF_02578	5.83e-87	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
NPEPPOKF_02579	2.63e-146	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
NPEPPOKF_02580	2.16e-241	ynjC	-	-	S	-	-	-	Cell surface protein
NPEPPOKF_02581	3.15e-130	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
NPEPPOKF_02582	1.47e-83	-	-	-	-	-	-	-	-
NPEPPOKF_02583	7.39e-300	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
NPEPPOKF_02584	4.13e-157	-	-	-	-	-	-	-	-
NPEPPOKF_02585	1.06e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
NPEPPOKF_02586	3.25e-81	ytcD	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NPEPPOKF_02587	5.78e-269	-	-	-	EGP	-	-	-	Major Facilitator
NPEPPOKF_02588	7.81e-148	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
NPEPPOKF_02589	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
NPEPPOKF_02590	6.58e-173	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
NPEPPOKF_02591	5.93e-281	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
NPEPPOKF_02592	1.15e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NPEPPOKF_02593	2.09e-213	-	-	-	GM	-	-	-	NmrA-like family
NPEPPOKF_02594	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
NPEPPOKF_02595	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
NPEPPOKF_02596	1.62e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF1905)
NPEPPOKF_02597	2.56e-83	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
NPEPPOKF_02598	1.89e-169	-	-	-	S	-	-	-	KR domain
NPEPPOKF_02599	5.61e-39	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NPEPPOKF_02600	1.74e-184	yxeH	-	-	S	-	-	-	hydrolase
NPEPPOKF_02601	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NPEPPOKF_02602	1.68e-146	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NPEPPOKF_02603	1.17e-305	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
NPEPPOKF_02604	7.29e-61	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system galactitol-specific IIB component
NPEPPOKF_02605	1.58e-101	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NPEPPOKF_02606	0.0	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NPEPPOKF_02607	9.14e-146	gph3	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
NPEPPOKF_02608	5.26e-247	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
NPEPPOKF_02609	8.37e-296	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
NPEPPOKF_02610	6e-60	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NPEPPOKF_02611	3.99e-106	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NPEPPOKF_02612	1.83e-146	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
NPEPPOKF_02613	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
NPEPPOKF_02614	3.76e-180	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
NPEPPOKF_02615	6.47e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
NPEPPOKF_02616	8.16e-48	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NPEPPOKF_02617	3.21e-127	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NPEPPOKF_02618	3.89e-205	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NPEPPOKF_02619	0.0	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NPEPPOKF_02620	4.01e-263	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NPEPPOKF_02621	9.03e-173	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
NPEPPOKF_02622	1.33e-196	nanK	-	-	GK	-	-	-	ROK family
NPEPPOKF_02623	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
NPEPPOKF_02624	4.97e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NPEPPOKF_02625	2.5e-147	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
NPEPPOKF_02626	3.59e-301	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
NPEPPOKF_02628	1.12e-207	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
NPEPPOKF_02629	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NPEPPOKF_02630	9.52e-264	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
NPEPPOKF_02631	2.68e-75	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
NPEPPOKF_02632	1.6e-246	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
NPEPPOKF_02633	7.21e-150	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
NPEPPOKF_02634	6.31e-222	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NPEPPOKF_02635	1.29e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NPEPPOKF_02636	1.83e-156	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
NPEPPOKF_02637	2.24e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
NPEPPOKF_02638	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
NPEPPOKF_02639	1.52e-231	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
NPEPPOKF_02640	1.64e-17	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
NPEPPOKF_02641	7.12e-170	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NPEPPOKF_02642	9.28e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NPEPPOKF_02643	2.81e-178	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
NPEPPOKF_02644	1.08e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
NPEPPOKF_02660	0.0	acdH	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
NPEPPOKF_02661	8.16e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
NPEPPOKF_02663	2.75e-304	xylP1	-	-	G	-	-	-	MFS/sugar transport protein
NPEPPOKF_02664	5.81e-170	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
NPEPPOKF_02665	3.48e-40	-	-	-	-	-	-	-	-
NPEPPOKF_02666	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NPEPPOKF_02667	6.4e-54	-	-	-	-	-	-	-	-
NPEPPOKF_02668	7.31e-122	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
NPEPPOKF_02669	6.8e-224	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NPEPPOKF_02670	3.08e-81	-	-	-	S	-	-	-	CHY zinc finger
NPEPPOKF_02671	3.51e-281	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NPEPPOKF_02672	1.57e-280	-	-	-	-	-	-	-	-
NPEPPOKF_02673	1.15e-198	tagG	-	-	U	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
NPEPPOKF_02674	9.42e-258	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NPEPPOKF_02675	3.93e-59	-	-	-	-	-	-	-	-
NPEPPOKF_02676	4.63e-119	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
NPEPPOKF_02677	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
NPEPPOKF_02678	3.5e-307	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
NPEPPOKF_02679	4.2e-88	gcsH1	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Glycine cleavage H-protein
NPEPPOKF_02680	4.29e-227	-	-	-	-	-	-	-	-
NPEPPOKF_02681	3.27e-168	-	-	-	-	-	-	-	-
NPEPPOKF_02682	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
NPEPPOKF_02683	3.01e-75	-	-	-	-	-	-	-	-
NPEPPOKF_02684	3.74e-284	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NPEPPOKF_02685	9.81e-33	-	-	-	S	ko:K02348	-	ko00000	GNAT family
NPEPPOKF_02686	1.02e-98	-	-	-	K	-	-	-	Transcriptional regulator
NPEPPOKF_02687	9.59e-288	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
NPEPPOKF_02688	2.18e-53	-	-	-	-	-	-	-	-
NPEPPOKF_02689	3.07e-264	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NPEPPOKF_02690	1.31e-179	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NPEPPOKF_02691	6.34e-190	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NPEPPOKF_02692	8.8e-264	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NPEPPOKF_02693	3.68e-125	-	-	-	K	-	-	-	Cupin domain
NPEPPOKF_02694	8.08e-110	-	-	-	S	-	-	-	ASCH
NPEPPOKF_02695	1.88e-111	-	-	-	K	-	-	-	GNAT family
NPEPPOKF_02696	2.14e-117	-	-	-	K	-	-	-	acetyltransferase
NPEPPOKF_02697	2.06e-30	-	-	-	-	-	-	-	-
NPEPPOKF_02698	5.05e-79	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
NPEPPOKF_02699	1.85e-208	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NPEPPOKF_02700	1.08e-243	-	-	-	-	-	-	-	-
NPEPPOKF_02701	2.07e-40	-	-	-	-	-	-	-	-
NPEPPOKF_02702	7.92e-140	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NPEPPOKF_02703	5.93e-73	-	-	-	S	-	-	-	branched-chain amino acid
NPEPPOKF_02704	2.05e-167	-	-	-	E	-	-	-	branched-chain amino acid
NPEPPOKF_02705	1.6e-114	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
NPEPPOKF_02706	3.1e-304	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NPEPPOKF_02707	5.61e-273	hpk31	-	-	T	-	-	-	Histidine kinase
NPEPPOKF_02708	1.14e-159	vanR	-	-	K	-	-	-	response regulator
NPEPPOKF_02709	2.4e-161	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
NPEPPOKF_02710	3.3e-208	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NPEPPOKF_02711	1.42e-269	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NPEPPOKF_02712	3.49e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
NPEPPOKF_02713	6.6e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NPEPPOKF_02714	1.4e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
NPEPPOKF_02715	7.16e-201	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NPEPPOKF_02716	1.01e-175	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
NPEPPOKF_02717	8.63e-191	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NPEPPOKF_02718	1.81e-168	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
NPEPPOKF_02719	4.76e-288	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
NPEPPOKF_02720	2.87e-270	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
NPEPPOKF_02721	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
NPEPPOKF_02722	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
NPEPPOKF_02723	6.46e-221	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
NPEPPOKF_02724	1.04e-98	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPEPPOKF_02726	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
NPEPPOKF_02727	1.53e-26	-	-	-	-	-	-	-	-
NPEPPOKF_02728	4.95e-103	-	-	-	-	-	-	-	-
NPEPPOKF_02730	1.32e-224	-	-	-	M	-	-	-	Peptidase family S41
NPEPPOKF_02731	7.34e-124	-	-	-	K	-	-	-	Helix-turn-helix domain
NPEPPOKF_02732	5.05e-05	-	-	-	S	-	-	-	FRG
NPEPPOKF_02733	6.34e-39	-	-	-	-	-	-	-	-
NPEPPOKF_02734	1.4e-13	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NPEPPOKF_02735	7.1e-81	-	-	-	S	-	-	-	Protein of unknown function (DUF2992)
NPEPPOKF_02736	9.04e-78	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
NPEPPOKF_02737	1.11e-59	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
NPEPPOKF_02738	1.26e-137	-	-	-	L	-	-	-	Integrase
NPEPPOKF_02739	2.08e-60	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
NPEPPOKF_02740	3.03e-49	-	-	-	K	-	-	-	sequence-specific DNA binding
NPEPPOKF_02741	9.13e-70	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
NPEPPOKF_02742	2.78e-231	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
NPEPPOKF_02743	1.98e-72	repA	-	-	S	-	-	-	Replication initiator protein A
NPEPPOKF_02744	1.32e-57	-	-	-	-	-	-	-	-
NPEPPOKF_02745	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
NPEPPOKF_02747	3.53e-38	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NPEPPOKF_02748	1.92e-18	mpr	-	-	E	-	-	-	Trypsin-like serine protease
NPEPPOKF_02750	3.53e-65	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NPEPPOKF_02751	2.63e-44	-	-	-	-	-	-	-	-
NPEPPOKF_02752	2.96e-246	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
NPEPPOKF_02753	4.33e-162	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain protein
NPEPPOKF_02754	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
NPEPPOKF_02755	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
NPEPPOKF_02756	5.79e-08	-	-	-	-	-	-	-	-
NPEPPOKF_02757	8.94e-91	-	-	-	-	-	-	-	-
NPEPPOKF_02758	0.0	-	-	-	S	-	-	-	MucBP domain
NPEPPOKF_02759	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
NPEPPOKF_02760	4.33e-205	-	-	-	K	-	-	-	LysR substrate binding domain
NPEPPOKF_02761	1.85e-201	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
NPEPPOKF_02762	0.0	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
NPEPPOKF_02763	0.0	lepA2	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NPEPPOKF_02764	6.88e-152	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NPEPPOKF_02765	7.19e-89	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
NPEPPOKF_02766	9.45e-299	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NPEPPOKF_02767	3.74e-302	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NPEPPOKF_02768	2.83e-206	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NPEPPOKF_02769	2.91e-190	malA	-	-	S	-	-	-	maltodextrose utilization protein MalA
NPEPPOKF_02770	0.0	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
NPEPPOKF_02771	2.44e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NPEPPOKF_02772	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
NPEPPOKF_02773	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
NPEPPOKF_02774	3.26e-102	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
NPEPPOKF_02775	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
NPEPPOKF_02776	2.66e-132	-	-	-	G	-	-	-	Glycogen debranching enzyme
NPEPPOKF_02777	5.6e-14	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
NPEPPOKF_02778	6.72e-208	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
NPEPPOKF_02779	2.02e-192	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
NPEPPOKF_02780	1.04e-94	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
NPEPPOKF_02781	1.1e-93	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
NPEPPOKF_02782	5.74e-32	-	-	-	-	-	-	-	-
NPEPPOKF_02783	1.37e-116	-	-	-	-	-	-	-	-
NPEPPOKF_02784	1.81e-50	ydaS	-	-	S	-	-	-	Transglycosylase associated protein
NPEPPOKF_02785	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase family
NPEPPOKF_02786	1.71e-59	-	-	-	S	-	-	-	MORN repeat
NPEPPOKF_02787	3.39e-52	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
NPEPPOKF_02788	5.3e-157	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
NPEPPOKF_02789	4.29e-101	-	-	-	-	-	-	-	-
NPEPPOKF_02790	5.09e-51	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
NPEPPOKF_02791	2.42e-127	-	-	-	FG	-	-	-	HIT domain
NPEPPOKF_02792	4.27e-223	ydhF	-	-	S	-	-	-	Aldo keto reductase
NPEPPOKF_02793	5.17e-70	-	-	-	S	-	-	-	Pfam:DUF59
NPEPPOKF_02794	4.56e-206	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NPEPPOKF_02795	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
NPEPPOKF_02796	1.87e-249	-	-	-	V	-	-	-	Beta-lactamase
NPEPPOKF_02797	3.74e-125	-	-	-	V	-	-	-	VanZ like family
NPEPPOKF_02798	2.81e-181	-	-	-	K	-	-	-	Helix-turn-helix domain
NPEPPOKF_02799	2.97e-51	-	-	-	S	ko:K07343	-	ko00000	TfoX C-terminal domain
NPEPPOKF_02800	3.56e-288	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
NPEPPOKF_02801	0.0	-	-	-	-	-	-	-	-
NPEPPOKF_02802	3.15e-98	-	-	-	-	-	-	-	-
NPEPPOKF_02803	7.81e-241	-	-	-	S	-	-	-	Cell surface protein
NPEPPOKF_02804	6.02e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
NPEPPOKF_02805	4.31e-179	-	-	-	-	-	-	-	-
NPEPPOKF_02806	2.82e-236	-	-	-	S	-	-	-	DUF218 domain
NPEPPOKF_02807	3.26e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NPEPPOKF_02808	9.06e-193	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
NPEPPOKF_02809	5.78e-292	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NPEPPOKF_02810	1.96e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
NPEPPOKF_02811	5.3e-49	-	-	-	-	-	-	-	-
NPEPPOKF_02812	2.95e-57	-	-	-	S	-	-	-	ankyrin repeats
NPEPPOKF_02813	5.13e-119	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
NPEPPOKF_02814	7.59e-64	-	-	-	-	-	-	-	-
NPEPPOKF_02815	6.83e-274	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
NPEPPOKF_02816	8.05e-178	-	-	-	F	-	-	-	NUDIX domain
NPEPPOKF_02817	2.68e-32	-	-	-	-	-	-	-	-
NPEPPOKF_02819	8.51e-209	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NPEPPOKF_02820	1.23e-222	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
NPEPPOKF_02821	3.43e-106	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
NPEPPOKF_02822	2.29e-48	-	-	-	-	-	-	-	-
NPEPPOKF_02823	4.54e-45	-	-	-	-	-	-	-	-
NPEPPOKF_02824	9.39e-277	-	-	-	T	-	-	-	diguanylate cyclase
NPEPPOKF_02825	7.76e-100	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
NPEPPOKF_02826	4.6e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
NPEPPOKF_02827	1.78e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
NPEPPOKF_02828	2.94e-155	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
NPEPPOKF_02829	1.36e-77	-	-	-	-	-	-	-	-
NPEPPOKF_02830	7.79e-112	-	-	-	K	-	-	-	MerR HTH family regulatory protein
NPEPPOKF_02831	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
NPEPPOKF_02832	2.72e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
NPEPPOKF_02833	1.46e-170	-	-	-	-	-	-	-	-
NPEPPOKF_02835	2.55e-218	-	-	-	EG	-	-	-	EamA-like transporter family
NPEPPOKF_02836	1.06e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
NPEPPOKF_02837	2.12e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
NPEPPOKF_02838	1.45e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
NPEPPOKF_02839	0.0	yclK	-	-	T	-	-	-	Histidine kinase
NPEPPOKF_02840	5.23e-277	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
NPEPPOKF_02841	2.51e-200	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
NPEPPOKF_02842	6.66e-115	-	-	-	-	-	-	-	-
NPEPPOKF_02843	2.29e-225	-	-	-	L	-	-	-	Initiator Replication protein
NPEPPOKF_02844	3.67e-41	-	-	-	-	-	-	-	-
NPEPPOKF_02845	1.87e-139	-	-	-	L	-	-	-	Integrase
NPEPPOKF_02846	4.17e-55	-	-	-	K	-	-	-	prlF antitoxin for toxin YhaV_toxin
NPEPPOKF_02847	1.03e-77	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
NPEPPOKF_02848	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
NPEPPOKF_02850	2.78e-80	-	-	-	M	-	-	-	Cna protein B-type domain
NPEPPOKF_02851	0.0	merA	1.16.1.1	-	C	ko:K00520,ko:K21739	-	ko00000,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NPEPPOKF_02852	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
NPEPPOKF_02853	4.67e-35	-	-	-	-	-	-	-	-
NPEPPOKF_02854	6.04e-43	-	-	-	-	-	-	-	-
NPEPPOKF_02855	1.74e-18	-	-	-	Q	-	-	-	Methyltransferase
NPEPPOKF_02856	0.0	-	3.6.3.44	-	P	ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
NPEPPOKF_02857	2.62e-76	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
NPEPPOKF_02858	1.89e-254	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
NPEPPOKF_02859	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPEPPOKF_02860	2.1e-33	-	-	-	-	-	-	-	-
NPEPPOKF_02861	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
NPEPPOKF_02862	9.51e-142	XK27_07075	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
NPEPPOKF_02863	1.07e-74	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
NPEPPOKF_02864	2.13e-167	-	-	-	L	-	-	-	Helix-turn-helix domain
NPEPPOKF_02865	4.73e-206	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
NPEPPOKF_02866	6.16e-298	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
NPEPPOKF_02867	5.87e-51	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
NPEPPOKF_02868	1.01e-117	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
NPEPPOKF_02869	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
NPEPPOKF_02870	4.2e-22	-	-	-	-	-	-	-	-
NPEPPOKF_02871	1.54e-125	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NPEPPOKF_02872	2.1e-78	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
NPEPPOKF_02873	2.64e-129	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
NPEPPOKF_02874	2.43e-241	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
NPEPPOKF_02876	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
NPEPPOKF_02877	2.51e-103	-	-	-	T	-	-	-	Universal stress protein family
NPEPPOKF_02878	7.43e-130	padR	-	-	K	-	-	-	Virulence activator alpha C-term
NPEPPOKF_02879	1.61e-74	mleR	-	-	K	-	-	-	LysR substrate binding domain
NPEPPOKF_02880	3.55e-169	-	-	-	K	-	-	-	LysR family
NPEPPOKF_02881	0.0	-	-	-	C	-	-	-	FMN_bind
NPEPPOKF_02882	2.17e-304	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
NPEPPOKF_02883	3.99e-101	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
NPEPPOKF_02886	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
NPEPPOKF_02887	7.39e-83	-	-	-	G	-	-	-	COG0662 Mannose-6-phosphate isomerase
NPEPPOKF_02888	2.85e-57	-	-	-	-	-	-	-	-
NPEPPOKF_02889	2.06e-66	ykoF	-	-	S	-	-	-	YKOF-related Family
NPEPPOKF_02890	5.63e-15	-	-	-	E	-	-	-	glutamine synthetase
NPEPPOKF_02891	9.73e-245	-	-	-	E	-	-	-	glutamine synthetase
NPEPPOKF_02892	3.2e-76	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
NPEPPOKF_02893	3.16e-59	-	-	-	T	ko:K07172	-	ko00000,ko02048	Antidote-toxin recognition MazE, bacterial antitoxin
NPEPPOKF_02894	9.24e-140	-	-	-	L	-	-	-	Integrase
NPEPPOKF_02895	3.72e-21	-	-	-	-	-	-	-	-
NPEPPOKF_02896	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
NPEPPOKF_02897	5.49e-237	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
NPEPPOKF_02898	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
NPEPPOKF_02899	1.19e-124	-	-	-	L	-	-	-	Resolvase, N terminal domain
NPEPPOKF_02900	7.8e-75	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
NPEPPOKF_02901	9.57e-315	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
NPEPPOKF_02902	2.37e-49	-	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
NPEPPOKF_02904	1.28e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Transcriptional regulator
NPEPPOKF_02905	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
NPEPPOKF_02906	9.4e-148	mdt(A)	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Major facilitator Superfamily
NPEPPOKF_02907	9.33e-249	-	-	-	U	ko:K07085	-	ko00000	Predicted Permease Membrane Region
NPEPPOKF_02908	5.32e-298	aspD	4.1.1.12	-	E	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	ko00000,ko00001,ko01000	Aminotransferase class I and II
NPEPPOKF_02909	1.48e-81	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NPEPPOKF_02910	2.09e-151	-	-	-	-	-	-	-	-
NPEPPOKF_02911	1.16e-84	-	-	-	-	-	-	-	-
NPEPPOKF_02912	6.47e-10	-	-	-	P	-	-	-	Cation efflux family
NPEPPOKF_02913	8.86e-35	-	-	-	-	-	-	-	-
NPEPPOKF_02914	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
NPEPPOKF_02915	2.44e-303	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NPEPPOKF_02916	1.89e-71	-	-	-	-	-	-	-	-
NPEPPOKF_02917	7.86e-68	-	-	-	L	-	-	-	Transposase IS66 family
NPEPPOKF_02918	2.89e-256	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
NPEPPOKF_02919	3.9e-34	-	-	-	-	-	-	-	-
NPEPPOKF_02920	5.03e-75	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
NPEPPOKF_02921	4.16e-06	-	-	-	S	-	-	-	Transposase C of IS166 homeodomain
NPEPPOKF_02924	4.87e-45	-	-	-	-	-	-	-	-
NPEPPOKF_02925	8.69e-185	-	-	-	D	-	-	-	AAA domain
NPEPPOKF_02926	1.95e-25	-	-	-	-	-	-	-	-
NPEPPOKF_02927	3.1e-172	repA	-	-	S	-	-	-	Replication initiator protein A
NPEPPOKF_02928	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
NPEPPOKF_02929	5.62e-49	kdpE	-	-	KT	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
NPEPPOKF_02930	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
NPEPPOKF_02931	1.74e-72	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NPEPPOKF_02932	5.17e-70	-	-	-	S	-	-	-	Nitroreductase
NPEPPOKF_02933	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
NPEPPOKF_02934	4.21e-174	bgaR	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
NPEPPOKF_02935	4.31e-196	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
NPEPPOKF_02936	1.39e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NPEPPOKF_02937	3.23e-150	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
NPEPPOKF_02938	4.27e-146	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
NPEPPOKF_02940	1.95e-62	-	-	-	S	-	-	-	Family of unknown function (DUF5388)
NPEPPOKF_02941	6.89e-190	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
NPEPPOKF_02942	5.6e-292	-	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
NPEPPOKF_02943	2.13e-159	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NPEPPOKF_02944	1.86e-210	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
NPEPPOKF_02945	3.77e-278	-	-	-	EGP	-	-	-	Major Facilitator
NPEPPOKF_02946	1.62e-150	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NPEPPOKF_02947	8.61e-19	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	adenosylhomocysteinase activity
NPEPPOKF_02948	5.41e-89	-	-	-	C	-	-	-	lyase activity
NPEPPOKF_02949	2.64e-233	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
NPEPPOKF_02950	3.79e-26	-	-	-	-	-	-	-	-
NPEPPOKF_02952	7.57e-122	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NPEPPOKF_02953	3.47e-244	-	1.1.1.219	-	GM	ko:K00091	-	ko00000,ko01000	Male sterility protein
NPEPPOKF_02954	1.27e-129	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
NPEPPOKF_02955	4.93e-54	-	-	-	-	-	-	-	-
NPEPPOKF_02956	1.39e-36	-	-	-	-	-	-	-	-
NPEPPOKF_02957	1.91e-34	-	-	-	-	-	-	-	-
NPEPPOKF_02958	2.44e-54	-	-	-	-	-	-	-	-
NPEPPOKF_02959	2.83e-58	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
NPEPPOKF_02960	6.45e-111	-	-	-	-	-	-	-	-
NPEPPOKF_02961	8.5e-55	-	-	-	-	-	-	-	-
NPEPPOKF_02962	1.34e-34	-	-	-	-	-	-	-	-
NPEPPOKF_02963	5.43e-167	-	-	-	S	-	-	-	Phage Mu protein F like protein
NPEPPOKF_02964	3.62e-22	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
NPEPPOKF_02965	9.4e-122	-	-	-	L	-	-	-	4.5 Transposon and IS
NPEPPOKF_02966	1.15e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase
NPEPPOKF_02968	6.03e-36	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPEPPOKF_02969	3.11e-17	-	-	-	S	-	-	-	protein with an alpha beta hydrolase fold
NPEPPOKF_02970	2.03e-31	-	-	-	S	-	-	-	Family of unknown function (DUF5388)
NPEPPOKF_02971	1.18e-184	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
NPEPPOKF_02973	6.13e-127	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
NPEPPOKF_02974	1.18e-192	degV	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
NPEPPOKF_02975	1.32e-107	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
NPEPPOKF_02976	2.26e-39	-	-	-	L	-	-	-	manually curated
NPEPPOKF_02977	2.67e-75	-	-	-	-	-	-	-	-
NPEPPOKF_02978	2.54e-42	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
NPEPPOKF_02979	4.19e-54	-	-	-	-	-	-	-	-
NPEPPOKF_02980	1.18e-194	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
NPEPPOKF_02981	3.72e-14	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
NPEPPOKF_02982	9.51e-135	-	-	-	-	-	-	-	-
NPEPPOKF_02983	1.41e-163	-	-	-	P	-	-	-	integral membrane protein, YkoY family
NPEPPOKF_02985	3.47e-47	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
NPEPPOKF_02986	4.05e-211	-	-	-	L	-	-	-	PFAM Integrase catalytic region
NPEPPOKF_02987	3.55e-76	-	-	-	-	-	-	-	-
NPEPPOKF_02988	2.43e-91	-	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
NPEPPOKF_02989	6.01e-49	-	-	-	S	-	-	-	Bacteriophage holin
NPEPPOKF_02990	2.58e-147	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NPEPPOKF_02991	8.81e-48	-	-	-	L	-	-	-	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NPEPPOKF_02993	4.64e-18	-	-	-	-	-	-	-	-
NPEPPOKF_02995	1.95e-114	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
NPEPPOKF_02996	3.76e-115	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
NPEPPOKF_02997	8.37e-108	-	-	-	L	-	-	-	Transposase DDE domain
NPEPPOKF_02998	2.69e-105	-	-	-	L	ko:K07498	-	ko00000	DDE domain