ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HLJEPGAF_00001 7.17e-62 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HLJEPGAF_00002 2.15e-07 - - - K - - - transcriptional regulator
HLJEPGAF_00003 5.58e-274 - - - S - - - membrane
HLJEPGAF_00004 1.51e-105 - - - K - - - Bacterial regulatory proteins, tetR family
HLJEPGAF_00005 0.0 - - - S - - - Zinc finger, swim domain protein
HLJEPGAF_00006 8.09e-146 - - - GM - - - epimerase
HLJEPGAF_00007 6.34e-90 - - - S - - - Protein of unknown function (DUF1722)
HLJEPGAF_00008 2.65e-93 spx2 - - P ko:K16509 - ko00000 ArsC family
HLJEPGAF_00009 1.4e-137 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
HLJEPGAF_00010 1.68e-176 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
HLJEPGAF_00011 0.0 nox - - P - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HLJEPGAF_00012 1.3e-264 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HLJEPGAF_00013 4.38e-102 - - - K - - - Transcriptional regulator
HLJEPGAF_00014 4.6e-307 - - - U ko:K18926 - ko00000,ko00002,ko02000 Major Facilitator Superfamily
HLJEPGAF_00015 1.27e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HLJEPGAF_00016 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
HLJEPGAF_00017 1.68e-229 - - - C - - - Zinc-binding dehydrogenase
HLJEPGAF_00018 4.8e-278 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
HLJEPGAF_00019 1.93e-266 - - - - - - - -
HLJEPGAF_00020 6.11e-118 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
HLJEPGAF_00021 2.65e-81 - - - P - - - Rhodanese Homology Domain
HLJEPGAF_00022 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HLJEPGAF_00023 2.74e-112 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HLJEPGAF_00024 2.08e-213 drrA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HLJEPGAF_00025 2.52e-165 drrB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
HLJEPGAF_00026 1.75e-295 - - - M - - - O-Antigen ligase
HLJEPGAF_00027 6.85e-164 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HLJEPGAF_00028 1.09e-249 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HLJEPGAF_00029 1.29e-298 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HLJEPGAF_00030 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HLJEPGAF_00032 7.03e-40 - - - S - - - Protein of unknown function (DUF2929)
HLJEPGAF_00033 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HLJEPGAF_00034 8.69e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HLJEPGAF_00035 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
HLJEPGAF_00036 2.51e-98 ytwI - - S - - - Protein of unknown function (DUF441)
HLJEPGAF_00037 4.59e-217 yitL - - S ko:K00243 - ko00000 S1 domain
HLJEPGAF_00038 3.13e-211 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
HLJEPGAF_00039 3.99e-92 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLJEPGAF_00040 7.1e-176 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HLJEPGAF_00041 1.3e-132 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HLJEPGAF_00042 2.69e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HLJEPGAF_00043 2.24e-126 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HLJEPGAF_00044 3.38e-252 - - - S - - - Helix-turn-helix domain
HLJEPGAF_00045 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HLJEPGAF_00046 1.25e-39 - - - M - - - Lysin motif
HLJEPGAF_00047 1.27e-151 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HLJEPGAF_00048 1.98e-281 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HLJEPGAF_00049 5.89e-314 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HLJEPGAF_00050 5.57e-55 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HLJEPGAF_00051 2.08e-284 XK27_05225 - - S - - - Tetratricopeptide repeat protein
HLJEPGAF_00052 1.29e-192 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HLJEPGAF_00053 1.39e-185 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HLJEPGAF_00054 6.04e-290 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HLJEPGAF_00055 6.46e-109 - - - - - - - -
HLJEPGAF_00056 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
HLJEPGAF_00057 6.7e-241 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HLJEPGAF_00058 1.8e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HLJEPGAF_00059 2.03e-189 WQ51_01275 - - S - - - EDD domain protein, DegV family
HLJEPGAF_00060 1.19e-208 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
HLJEPGAF_00061 3.29e-147 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
HLJEPGAF_00062 9.33e-48 yozE - - S - - - Belongs to the UPF0346 family
HLJEPGAF_00063 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HLJEPGAF_00064 0.0 qacA - - EGP - - - Major Facilitator
HLJEPGAF_00065 4.28e-253 XK27_00915 - - C - - - Luciferase-like monooxygenase
HLJEPGAF_00066 3.53e-160 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
HLJEPGAF_00067 1.27e-222 - - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
HLJEPGAF_00068 1.73e-219 cpsY - - K - - - Transcriptional regulator, LysR family
HLJEPGAF_00069 5.99e-291 XK27_05470 - - E - - - Methionine synthase
HLJEPGAF_00071 2.25e-207 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HLJEPGAF_00072 8.64e-177 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HLJEPGAF_00073 2.33e-202 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
HLJEPGAF_00074 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HLJEPGAF_00075 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HLJEPGAF_00076 1.5e-227 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
HLJEPGAF_00077 6.84e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HLJEPGAF_00078 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HLJEPGAF_00079 3.64e-217 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HLJEPGAF_00080 2.4e-137 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HLJEPGAF_00081 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HLJEPGAF_00082 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HLJEPGAF_00083 2.21e-227 - - - K - - - Transcriptional regulator
HLJEPGAF_00084 3.21e-215 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
HLJEPGAF_00085 3.8e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
HLJEPGAF_00086 9.17e-126 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HLJEPGAF_00087 1.07e-43 - - - S - - - YozE SAM-like fold
HLJEPGAF_00088 3.59e-204 - - - L - - - Phage integrase, N-terminal SAM-like domain
HLJEPGAF_00089 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HLJEPGAF_00090 4.49e-315 - - - M - - - Glycosyl transferase family group 2
HLJEPGAF_00091 3.22e-87 - - - - - - - -
HLJEPGAF_00092 0.0 gshR1 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
HLJEPGAF_00093 1.48e-98 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HLJEPGAF_00094 4.87e-123 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HLJEPGAF_00095 0.0 tarL 2.7.8.14, 2.7.8.47 - H ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HLJEPGAF_00096 1.43e-273 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - H ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HLJEPGAF_00097 6.51e-247 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HLJEPGAF_00098 2.13e-151 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HLJEPGAF_00099 4.76e-290 - - - - - - - -
HLJEPGAF_00100 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HLJEPGAF_00101 7.79e-78 - - - - - - - -
HLJEPGAF_00102 2.79e-181 - - - - - - - -
HLJEPGAF_00103 1.06e-312 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HLJEPGAF_00104 1.05e-176 XK27_00890 - - S ko:K08974 - ko00000 Domain of unknown function (DUF368)
HLJEPGAF_00105 9.3e-167 yejC - - S - - - Protein of unknown function (DUF1003)
HLJEPGAF_00106 1.33e-67 XK27_08430 - - S - - - Staphylococcal protein of unknown function (DUF960)
HLJEPGAF_00108 6e-268 pmrB - - EGP - - - Major Facilitator Superfamily
HLJEPGAF_00109 4.87e-191 - - - C - - - Domain of unknown function (DUF4931)
HLJEPGAF_00110 2.37e-65 - - - - - - - -
HLJEPGAF_00111 1.27e-35 - - - - - - - -
HLJEPGAF_00112 1.96e-168 - - - S - - - Protein of unknown function (DUF975)
HLJEPGAF_00113 2.47e-101 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
HLJEPGAF_00114 4.53e-205 - - - S - - - EDD domain protein, DegV family
HLJEPGAF_00115 1.97e-87 - - - K - - - Transcriptional regulator
HLJEPGAF_00116 0.0 FbpA - - K - - - Fibronectin-binding protein
HLJEPGAF_00117 1.6e-171 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HLJEPGAF_00118 2.16e-208 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HLJEPGAF_00119 1.37e-119 - - - F - - - NUDIX domain
HLJEPGAF_00120 1.19e-176 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2087)
HLJEPGAF_00121 2.08e-92 - - - S - - - LuxR family transcriptional regulator
HLJEPGAF_00122 1.92e-168 cat 2.3.1.28 - V ko:K19271 - br01600,ko00000,ko01000,ko01504 Chloramphenicol acetyltransferase
HLJEPGAF_00125 1.9e-93 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
HLJEPGAF_00126 3.34e-144 - - - G - - - Phosphoglycerate mutase family
HLJEPGAF_00127 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HLJEPGAF_00128 4.89e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
HLJEPGAF_00129 1.9e-115 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HLJEPGAF_00130 9.72e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HLJEPGAF_00131 1.65e-97 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HLJEPGAF_00132 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
HLJEPGAF_00133 5.89e-81 esbA - - S - - - Family of unknown function (DUF5322)
HLJEPGAF_00134 3.28e-87 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
HLJEPGAF_00135 2.44e-267 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 FAD dependent oxidoreductase
HLJEPGAF_00136 2.13e-186 - - - S - - - hydrolase activity, acting on ester bonds
HLJEPGAF_00137 2.27e-247 - - - - - - - -
HLJEPGAF_00138 1.9e-156 - - - P ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HLJEPGAF_00139 4.35e-159 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
HLJEPGAF_00140 1.38e-232 - - - V - - - LD-carboxypeptidase
HLJEPGAF_00141 1.23e-311 - - - M ko:K07273 - ko00000 hydrolase, family 25
HLJEPGAF_00143 2.16e-208 - - - K - - - Transcriptional regulator
HLJEPGAF_00144 2.43e-206 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
HLJEPGAF_00145 1.66e-211 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
HLJEPGAF_00146 5.73e-100 - - - K - - - Winged helix DNA-binding domain
HLJEPGAF_00147 0.0 ycaM - - E - - - amino acid
HLJEPGAF_00148 2.38e-164 aroC1 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Type I 3-dehydroquinase
HLJEPGAF_00149 4.3e-44 - - - - - - - -
HLJEPGAF_00150 0.0 - - - M - - - Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HLJEPGAF_00151 9.78e-187 - - - M - - - Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HLJEPGAF_00152 0.0 - - - M - - - Domain of unknown function (DUF5011)
HLJEPGAF_00153 4.75e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
HLJEPGAF_00154 0.0 - - - - ko:K21471 - ko00000,ko01000,ko01002,ko01011 -
HLJEPGAF_00155 1.54e-131 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
HLJEPGAF_00156 1.96e-224 serA1 - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HLJEPGAF_00157 3.98e-204 - - - EG - - - EamA-like transporter family
HLJEPGAF_00158 6.86e-232 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HLJEPGAF_00159 5.06e-196 - - - S - - - hydrolase
HLJEPGAF_00160 7.63e-107 - - - - - - - -
HLJEPGAF_00161 1.75e-156 pgm7 - - G - - - Phosphoglycerate mutase family
HLJEPGAF_00162 1.4e-181 epsV - - S - - - glycosyl transferase family 2
HLJEPGAF_00163 1.23e-166 gntR - - K ko:K03489 - ko00000,ko03000 UTRA
HLJEPGAF_00164 1.86e-64 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HLJEPGAF_00165 6.7e-74 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
HLJEPGAF_00166 0.0 pbg5 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HLJEPGAF_00167 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HLJEPGAF_00168 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
HLJEPGAF_00169 4.29e-173 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HLJEPGAF_00170 9.24e-231 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HLJEPGAF_00171 6.09e-152 - - - K - - - Transcriptional regulator
HLJEPGAF_00172 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HLJEPGAF_00173 7.54e-115 yrxA - - S ko:K07105 - ko00000 3H domain
HLJEPGAF_00174 4.43e-294 - - - S - - - Sterol carrier protein domain
HLJEPGAF_00175 2.45e-269 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
HLJEPGAF_00176 3.25e-48 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
HLJEPGAF_00177 5.41e-172 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
HLJEPGAF_00178 2.26e-91 - - - FG - - - Scavenger mRNA decapping enzyme C-term binding
HLJEPGAF_00179 1.13e-132 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
HLJEPGAF_00180 5.88e-142 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HLJEPGAF_00181 2.99e-38 - - - S - - - Pentapeptide repeats (8 copies)
HLJEPGAF_00182 4.65e-186 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HLJEPGAF_00183 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
HLJEPGAF_00184 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HLJEPGAF_00186 1.21e-69 - - - - - - - -
HLJEPGAF_00187 1.52e-151 - - - - - - - -
HLJEPGAF_00188 1.16e-110 - - - F - - - belongs to the nudix hydrolase family
HLJEPGAF_00189 3.03e-299 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
HLJEPGAF_00190 4.79e-13 - - - - - - - -
HLJEPGAF_00191 5.92e-67 - - - - - - - -
HLJEPGAF_00192 1.76e-114 - - - - - - - -
HLJEPGAF_00193 5.7e-95 gtcA - - S - - - Teichoic acid glycosylation protein
HLJEPGAF_00194 3.64e-46 - - - - - - - -
HLJEPGAF_00195 1.1e-103 usp5 - - T - - - universal stress protein
HLJEPGAF_00196 4.21e-175 - - - - - - - -
HLJEPGAF_00197 7.89e-212 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HLJEPGAF_00198 8.2e-81 - - - K - - - Transcriptional regulator, GntR family
HLJEPGAF_00199 1.87e-53 - - - - - - - -
HLJEPGAF_00200 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HLJEPGAF_00201 2.05e-178 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HLJEPGAF_00202 3.7e-233 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
HLJEPGAF_00203 6.89e-190 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HLJEPGAF_00204 5.95e-153 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
HLJEPGAF_00205 4.81e-188 ptp3 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HLJEPGAF_00206 5.76e-243 lplL 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Bacterial lipoate protein ligase C-terminus
HLJEPGAF_00207 9.92e-143 - - - S - - - NADPH-dependent FMN reductase
HLJEPGAF_00208 4.57e-304 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
HLJEPGAF_00209 3.77e-104 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HLJEPGAF_00210 2.87e-270 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HLJEPGAF_00211 3.39e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HLJEPGAF_00212 1.17e-55 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLJEPGAF_00213 6.91e-164 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLJEPGAF_00214 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLJEPGAF_00215 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HLJEPGAF_00216 4.22e-243 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HLJEPGAF_00217 5.35e-133 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HLJEPGAF_00218 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HLJEPGAF_00219 9.06e-279 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HLJEPGAF_00220 1.83e-157 - - - E - - - Methionine synthase
HLJEPGAF_00221 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
HLJEPGAF_00222 1.85e-121 - - - - - - - -
HLJEPGAF_00223 1.25e-199 - - - T - - - EAL domain
HLJEPGAF_00224 2.24e-206 - - - GM - - - NmrA-like family
HLJEPGAF_00225 5.67e-280 pbuG - - S ko:K06901 - ko00000,ko02000 Permease family
HLJEPGAF_00226 3.1e-305 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
HLJEPGAF_00227 0.0 pucR_2 - - QT ko:K09684 - ko00000,ko03000 Purine catabolism regulatory protein-like family
HLJEPGAF_00228 7.13e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HLJEPGAF_00229 2.02e-219 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HLJEPGAF_00230 1.61e-308 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HLJEPGAF_00231 2.76e-271 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HLJEPGAF_00232 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HLJEPGAF_00233 1.04e-218 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HLJEPGAF_00234 1.55e-161 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HLJEPGAF_00235 5.46e-145 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HLJEPGAF_00236 1.12e-216 oroP - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
HLJEPGAF_00237 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HLJEPGAF_00238 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HLJEPGAF_00239 3.86e-124 - - - K - - - Acetyltransferase (GNAT) family
HLJEPGAF_00240 1.29e-148 - - - GM - - - NAD(P)H-binding
HLJEPGAF_00241 6.68e-207 mleR - - K - - - LysR family
HLJEPGAF_00242 2.09e-169 - - - S ko:K07090 - ko00000 membrane transporter protein
HLJEPGAF_00243 3.59e-26 - - - - - - - -
HLJEPGAF_00244 1.84e-204 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HLJEPGAF_00245 1.02e-277 araT2 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HLJEPGAF_00246 0.0 gabR - - K ko:K00375 - ko00000,ko03000 Bacterial regulatory proteins, gntR family
HLJEPGAF_00247 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HLJEPGAF_00248 4.71e-74 - - - S - - - SdpI/YhfL protein family
HLJEPGAF_00249 4.68e-161 - - - C - - - Zinc-binding dehydrogenase
HLJEPGAF_00250 9.75e-39 - - - C - - - Zinc-binding dehydrogenase
HLJEPGAF_00251 3.45e-83 - - - K - - - helix_turn_helix, mercury resistance
HLJEPGAF_00252 2.03e-271 yttB - - EGP - - - Major Facilitator
HLJEPGAF_00253 0.0 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
HLJEPGAF_00254 1.18e-114 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
HLJEPGAF_00255 0.0 yhdP - - S - - - Transporter associated domain
HLJEPGAF_00256 2.97e-76 - - - - - - - -
HLJEPGAF_00257 2.61e-96 hsp2 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HLJEPGAF_00258 1.55e-79 - - - - - - - -
HLJEPGAF_00259 1.7e-118 - - - K - - - Domain of unknown function (DUF1836)
HLJEPGAF_00260 8.05e-179 rrp8 - - K - - - LytTr DNA-binding domain
HLJEPGAF_00261 1.97e-150 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HLJEPGAF_00262 2.48e-178 - - - - - - - -
HLJEPGAF_00263 4.75e-117 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HLJEPGAF_00264 3.53e-169 - - - K - - - Transcriptional regulator
HLJEPGAF_00265 2.01e-209 - - - S - - - Putative esterase
HLJEPGAF_00266 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
HLJEPGAF_00267 1.25e-283 - - - M - - - Glycosyl transferases group 1
HLJEPGAF_00268 1.38e-30 - - - S - - - Protein of unknown function (DUF2929)
HLJEPGAF_00269 4.05e-64 - - - K - - - Cro/C1-type HTH DNA-binding domain
HLJEPGAF_00270 2.5e-203 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HLJEPGAF_00271 2.51e-103 uspA3 - - T - - - universal stress protein
HLJEPGAF_00272 0.0 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Bacterial SH3 domain
HLJEPGAF_00273 4.26e-250 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
HLJEPGAF_00274 4.15e-78 - - - - - - - -
HLJEPGAF_00275 1.65e-97 - - - - - - - -
HLJEPGAF_00276 6.94e-106 - - - S - - - Protein of unknown function (DUF2798)
HLJEPGAF_00277 2.57e-70 - - - - - - - -
HLJEPGAF_00278 3.89e-62 - - - - - - - -
HLJEPGAF_00279 3.87e-262 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
HLJEPGAF_00280 9.89e-74 ytpP - - CO - - - Thioredoxin
HLJEPGAF_00281 1.19e-186 - - - S ko:K06889 - ko00000 Dienelactone hydrolase family
HLJEPGAF_00282 1.83e-37 - - - - - - - -
HLJEPGAF_00283 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HLJEPGAF_00284 3.2e-70 - - - - - - - -
HLJEPGAF_00285 3.15e-78 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HLJEPGAF_00286 1.57e-179 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HLJEPGAF_00287 6.42e-123 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HLJEPGAF_00288 9.99e-53 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
HLJEPGAF_00289 1.6e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HLJEPGAF_00290 7.69e-300 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HLJEPGAF_00291 1.46e-77 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HLJEPGAF_00292 2.85e-293 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HLJEPGAF_00293 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HLJEPGAF_00294 4.49e-167 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HLJEPGAF_00295 3.33e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HLJEPGAF_00296 2.17e-244 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HLJEPGAF_00297 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HLJEPGAF_00298 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
HLJEPGAF_00299 7.09e-76 yloU - - S - - - Asp23 family, cell envelope-related function
HLJEPGAF_00300 1.61e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HLJEPGAF_00301 1.84e-160 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
HLJEPGAF_00302 3.16e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HLJEPGAF_00303 1.21e-209 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HLJEPGAF_00304 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HLJEPGAF_00305 1.62e-173 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
HLJEPGAF_00306 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HLJEPGAF_00307 1.01e-222 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HLJEPGAF_00308 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HLJEPGAF_00309 1.28e-276 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HLJEPGAF_00310 3.93e-41 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HLJEPGAF_00311 6.96e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HLJEPGAF_00312 8.28e-73 - - - - - - - -
HLJEPGAF_00313 1.36e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HLJEPGAF_00314 3.8e-224 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HLJEPGAF_00315 7.11e-135 opuCB - - E ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HLJEPGAF_00316 4.51e-284 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HLJEPGAF_00317 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HLJEPGAF_00318 2.15e-99 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HLJEPGAF_00319 4.49e-192 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
HLJEPGAF_00320 7.16e-201 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HLJEPGAF_00321 7.55e-44 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLJEPGAF_00322 3.28e-312 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLJEPGAF_00323 4.82e-194 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HLJEPGAF_00324 2.82e-91 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HLJEPGAF_00325 1.7e-96 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
HLJEPGAF_00326 1.43e-129 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HLJEPGAF_00327 4.08e-247 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HLJEPGAF_00328 2.33e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HLJEPGAF_00329 7.97e-71 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
HLJEPGAF_00330 1.55e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HLJEPGAF_00331 8.15e-125 - - - K - - - Transcriptional regulator
HLJEPGAF_00332 9.81e-27 - - - - - - - -
HLJEPGAF_00335 2.97e-41 - - - - - - - -
HLJEPGAF_00336 3.11e-73 - - - - - - - -
HLJEPGAF_00337 2.92e-126 - - - S - - - Protein conserved in bacteria
HLJEPGAF_00338 1.34e-232 - - - - - - - -
HLJEPGAF_00339 1.18e-205 - - - - - - - -
HLJEPGAF_00340 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HLJEPGAF_00341 7.79e-85 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
HLJEPGAF_00342 3.8e-224 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HLJEPGAF_00343 7.77e-179 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
HLJEPGAF_00344 1.44e-31 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
HLJEPGAF_00345 1.15e-89 yqhL - - P - - - Rhodanese-like protein
HLJEPGAF_00346 1.62e-141 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
HLJEPGAF_00347 2.6e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
HLJEPGAF_00348 6.33e-46 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
HLJEPGAF_00349 3.52e-153 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
HLJEPGAF_00350 9.29e-132 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HLJEPGAF_00351 5.33e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HLJEPGAF_00352 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HLJEPGAF_00353 0.0 - - - S - - - membrane
HLJEPGAF_00354 6.12e-72 yneR - - S - - - Belongs to the HesB IscA family
HLJEPGAF_00355 5.72e-99 - - - K - - - LytTr DNA-binding domain
HLJEPGAF_00356 9.72e-146 - - - S - - - membrane
HLJEPGAF_00357 1.09e-105 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HLJEPGAF_00358 7.5e-146 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
HLJEPGAF_00359 6.11e-249 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HLJEPGAF_00360 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HLJEPGAF_00361 6.88e-257 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HLJEPGAF_00362 2.58e-82 yodB - - K - - - Transcriptional regulator, HxlR family
HLJEPGAF_00363 1.72e-120 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HLJEPGAF_00364 4.46e-179 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLJEPGAF_00365 1.37e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
HLJEPGAF_00366 6.94e-209 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLJEPGAF_00367 4.18e-121 - - - S - - - SdpI/YhfL protein family
HLJEPGAF_00368 1.36e-288 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HLJEPGAF_00369 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
HLJEPGAF_00370 1.93e-218 ubiA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
HLJEPGAF_00371 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HLJEPGAF_00372 1.38e-155 csrR - - K - - - response regulator
HLJEPGAF_00373 2.56e-310 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
HLJEPGAF_00374 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HLJEPGAF_00375 1.09e-223 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HLJEPGAF_00376 3.06e-124 - - - S - - - Peptidase propeptide and YPEB domain
HLJEPGAF_00377 3.66e-127 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
HLJEPGAF_00378 3.04e-280 ylbM - - S - - - Belongs to the UPF0348 family
HLJEPGAF_00379 3.3e-180 yqeM - - Q - - - Methyltransferase
HLJEPGAF_00380 1.06e-76 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HLJEPGAF_00381 1.71e-149 yqeK - - H - - - Hydrolase, HD family
HLJEPGAF_00382 4.19e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HLJEPGAF_00383 2.19e-67 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
HLJEPGAF_00384 3.81e-276 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
HLJEPGAF_00385 5.7e-127 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
HLJEPGAF_00386 6.32e-114 - - - - - - - -
HLJEPGAF_00387 1.7e-281 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
HLJEPGAF_00388 3.97e-174 racD 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HLJEPGAF_00389 1.64e-83 ydeP - - K - - - Transcriptional regulator, HxlR family
HLJEPGAF_00390 1.18e-250 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HLJEPGAF_00391 7.03e-307 - - - L ko:K07478 - ko00000 AAA C-terminal domain
HLJEPGAF_00392 4.59e-73 - - - - - - - -
HLJEPGAF_00393 6.88e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HLJEPGAF_00394 6.92e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HLJEPGAF_00395 2.37e-109 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HLJEPGAF_00396 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HLJEPGAF_00397 3.5e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
HLJEPGAF_00398 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
HLJEPGAF_00399 1.58e-117 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HLJEPGAF_00400 1.92e-133 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HLJEPGAF_00401 3.19e-202 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HLJEPGAF_00402 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HLJEPGAF_00403 8.51e-155 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
HLJEPGAF_00404 1.04e-141 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
HLJEPGAF_00405 4.07e-60 - - - S - - - Iron-sulfur cluster assembly protein
HLJEPGAF_00406 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
HLJEPGAF_00407 2.71e-108 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
HLJEPGAF_00408 1.11e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HLJEPGAF_00409 5.21e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
HLJEPGAF_00410 1.1e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
HLJEPGAF_00411 2.87e-47 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
HLJEPGAF_00412 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
HLJEPGAF_00413 3.04e-29 - - - S - - - Virus attachment protein p12 family
HLJEPGAF_00415 1.96e-293 rodA - - D ko:K05837 - ko00000,ko03036 Cell cycle protein
HLJEPGAF_00416 0.0 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HLJEPGAF_00417 3.82e-184 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HLJEPGAF_00418 4.46e-281 ywtF_2 - - K - - - Cell envelope-related transcriptional attenuator domain
HLJEPGAF_00419 2.19e-131 - - - L - - - Helix-turn-helix domain
HLJEPGAF_00420 1.14e-226 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyltransferase like family 2
HLJEPGAF_00421 3.81e-87 - - - - - - - -
HLJEPGAF_00422 1.38e-98 - - - - - - - -
HLJEPGAF_00423 1.56e-276 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
HLJEPGAF_00424 7.8e-123 - - - - - - - -
HLJEPGAF_00425 7.22e-149 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HLJEPGAF_00426 7.68e-48 ynzC - - S - - - UPF0291 protein
HLJEPGAF_00427 3.96e-44 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
HLJEPGAF_00428 8.8e-155 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
HLJEPGAF_00429 2.11e-171 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
HLJEPGAF_00430 5.67e-64 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
HLJEPGAF_00431 1.92e-239 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLJEPGAF_00432 2.92e-172 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
HLJEPGAF_00433 6.33e-185 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HLJEPGAF_00434 1.88e-194 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HLJEPGAF_00435 3.01e-165 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HLJEPGAF_00436 9.83e-113 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HLJEPGAF_00437 3.17e-190 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HLJEPGAF_00438 1.13e-175 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HLJEPGAF_00439 4.64e-294 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HLJEPGAF_00440 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HLJEPGAF_00441 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HLJEPGAF_00442 9.74e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HLJEPGAF_00443 4.46e-275 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HLJEPGAF_00444 2.95e-65 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
HLJEPGAF_00445 3.28e-63 ylxQ - - J - - - ribosomal protein
HLJEPGAF_00446 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HLJEPGAF_00447 3.04e-71 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HLJEPGAF_00448 0.0 - - - G - - - Major Facilitator
HLJEPGAF_00449 3.67e-275 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HLJEPGAF_00450 1.63e-121 - - - - - - - -
HLJEPGAF_00451 1.19e-285 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HLJEPGAF_00452 1.21e-245 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
HLJEPGAF_00453 2.41e-113 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HLJEPGAF_00454 8.94e-221 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HLJEPGAF_00455 2.53e-240 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HLJEPGAF_00456 1.19e-169 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
HLJEPGAF_00457 4.42e-248 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HLJEPGAF_00458 4.52e-111 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HLJEPGAF_00459 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HLJEPGAF_00460 2.54e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HLJEPGAF_00461 8.49e-266 pbpX2 - - V - - - Beta-lactamase
HLJEPGAF_00462 8.59e-27 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
HLJEPGAF_00463 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLJEPGAF_00464 3.27e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
HLJEPGAF_00465 5.75e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLJEPGAF_00466 1.68e-312 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HLJEPGAF_00467 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HLJEPGAF_00468 1.01e-158 int7 - - L - - - Belongs to the 'phage' integrase family
HLJEPGAF_00471 1.73e-67 - - - - - - - -
HLJEPGAF_00472 4.78e-65 - - - - - - - -
HLJEPGAF_00473 5.28e-146 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
HLJEPGAF_00474 2.04e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
HLJEPGAF_00475 3.13e-172 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HLJEPGAF_00476 2.56e-76 - - - - - - - -
HLJEPGAF_00477 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HLJEPGAF_00478 8.2e-102 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HLJEPGAF_00479 2.43e-150 yjcF - - J - - - HAD-hyrolase-like
HLJEPGAF_00480 2.29e-207 - - - G - - - Fructosamine kinase
HLJEPGAF_00481 4.01e-200 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
HLJEPGAF_00482 2.47e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HLJEPGAF_00483 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HLJEPGAF_00484 2.61e-132 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HLJEPGAF_00485 4.35e-204 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HLJEPGAF_00486 1.84e-284 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HLJEPGAF_00487 1.42e-217 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HLJEPGAF_00488 1.78e-140 - - - C - - - Enoyl-(Acyl carrier protein) reductase
HLJEPGAF_00489 2.32e-194 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HLJEPGAF_00490 1.09e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HLJEPGAF_00491 9.21e-94 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
HLJEPGAF_00492 4.81e-229 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
HLJEPGAF_00493 3.14e-109 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HLJEPGAF_00494 1.15e-94 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
HLJEPGAF_00495 7.92e-217 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HLJEPGAF_00496 2.84e-189 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HLJEPGAF_00497 8.64e-224 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
HLJEPGAF_00498 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
HLJEPGAF_00499 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HLJEPGAF_00500 1.74e-251 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HLJEPGAF_00501 1.18e-85 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
HLJEPGAF_00502 4.94e-213 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HLJEPGAF_00503 5.23e-256 - - - - - - - -
HLJEPGAF_00504 1.43e-251 - - - - - - - -
HLJEPGAF_00505 6.05e-170 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HLJEPGAF_00506 1.03e-206 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HLJEPGAF_00507 0.000138 yjdF - - S - - - Protein of unknown function (DUF2992)
HLJEPGAF_00508 1.49e-147 - - - S - - - Psort location CytoplasmicMembrane, score
HLJEPGAF_00509 2.25e-93 - - - K - - - MarR family
HLJEPGAF_00510 6.64e-109 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HLJEPGAF_00512 4.17e-204 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HLJEPGAF_00513 1.27e-174 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
HLJEPGAF_00514 5.11e-266 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HLJEPGAF_00515 1.51e-132 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
HLJEPGAF_00516 0.0 nox4 - - C - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HLJEPGAF_00518 3.78e-221 cryZ 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
HLJEPGAF_00519 5.72e-207 - - - K - - - Transcriptional regulator
HLJEPGAF_00520 1.74e-101 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2255)
HLJEPGAF_00521 1.39e-143 - - - GM - - - NmrA-like family
HLJEPGAF_00522 8.81e-205 - - - S - - - Alpha beta hydrolase
HLJEPGAF_00523 2.49e-167 - - - K - - - Helix-turn-helix domain, rpiR family
HLJEPGAF_00524 2.31e-132 thgA3 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
HLJEPGAF_00525 7.21e-145 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
HLJEPGAF_00526 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
HLJEPGAF_00527 3.67e-154 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HLJEPGAF_00528 2.38e-140 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
HLJEPGAF_00529 9.82e-55 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HLJEPGAF_00530 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HLJEPGAF_00531 0.0 ydaO - - E - - - amino acid
HLJEPGAF_00532 7.29e-247 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
HLJEPGAF_00533 6.57e-199 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HLJEPGAF_00534 3.7e-149 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
HLJEPGAF_00535 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
HLJEPGAF_00536 2.94e-164 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
HLJEPGAF_00537 1.27e-129 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HLJEPGAF_00538 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HLJEPGAF_00539 3.41e-257 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HLJEPGAF_00540 1.05e-275 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
HLJEPGAF_00541 1.49e-170 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HLJEPGAF_00542 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HLJEPGAF_00543 2.31e-199 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HLJEPGAF_00544 9.05e-206 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HLJEPGAF_00545 5.04e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
HLJEPGAF_00546 9.78e-190 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HLJEPGAF_00547 4.47e-177 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HLJEPGAF_00548 1.55e-150 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
HLJEPGAF_00549 2.78e-65 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 positive regulation of macromolecule biosynthetic process
HLJEPGAF_00550 2.87e-71 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
HLJEPGAF_00551 2.55e-225 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HLJEPGAF_00552 6.26e-213 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HLJEPGAF_00553 4e-235 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HLJEPGAF_00554 1.13e-218 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HLJEPGAF_00555 6.37e-160 - - - T - - - Putative diguanylate phosphodiesterase
HLJEPGAF_00556 0.0 nox - - C - - - NADH oxidase
HLJEPGAF_00557 8.65e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HLJEPGAF_00558 4.31e-141 yviA - - S - - - Protein of unknown function (DUF421)
HLJEPGAF_00559 7.54e-99 - - - S - - - Protein of unknown function (DUF3290)
HLJEPGAF_00560 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HLJEPGAF_00561 5.9e-170 - - - T - - - Putative diguanylate phosphodiesterase
HLJEPGAF_00562 0.0 nox2 - - S - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HLJEPGAF_00563 1.89e-134 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HLJEPGAF_00564 5.33e-268 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
HLJEPGAF_00565 3.85e-151 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
HLJEPGAF_00566 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HLJEPGAF_00567 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HLJEPGAF_00568 2.21e-113 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HLJEPGAF_00569 7.5e-302 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HLJEPGAF_00570 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
HLJEPGAF_00571 3.51e-113 - - - S - - - Short repeat of unknown function (DUF308)
HLJEPGAF_00572 1.71e-207 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HLJEPGAF_00573 5.32e-242 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
HLJEPGAF_00574 1.21e-215 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HLJEPGAF_00575 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HLJEPGAF_00576 8.58e-223 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLJEPGAF_00577 5.11e-133 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HLJEPGAF_00579 1.14e-311 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Sigma-54 factor, core binding domain
HLJEPGAF_00580 5.75e-242 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
HLJEPGAF_00581 2.02e-245 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HLJEPGAF_00582 1.31e-285 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
HLJEPGAF_00583 7.15e-179 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HLJEPGAF_00584 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HLJEPGAF_00585 2.83e-168 - - - - - - - -
HLJEPGAF_00586 0.0 eriC - - P ko:K03281 - ko00000 chloride
HLJEPGAF_00587 3.55e-43 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HLJEPGAF_00588 3.83e-179 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
HLJEPGAF_00589 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HLJEPGAF_00590 2.4e-107 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HLJEPGAF_00591 0.0 - - - M - - - Domain of unknown function (DUF5011)
HLJEPGAF_00592 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HLJEPGAF_00593 9.36e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HLJEPGAF_00594 7.98e-137 - - - - - - - -
HLJEPGAF_00595 1.98e-199 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
HLJEPGAF_00596 1.4e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HLJEPGAF_00597 1.23e-227 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
HLJEPGAF_00598 1.29e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
HLJEPGAF_00599 2.52e-114 - - - J - - - Acetyltransferase (GNAT) domain
HLJEPGAF_00600 2.41e-129 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HLJEPGAF_00601 2.53e-198 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HLJEPGAF_00602 3.09e-213 ysjB - - S ko:K03810 - ko00000 Oxidoreductase family, NAD-binding Rossmann fold
HLJEPGAF_00603 6.24e-214 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
HLJEPGAF_00604 0.0 yvgP - - P ko:K03316 - ko00000 Sodium proton antiporter
HLJEPGAF_00605 3.07e-119 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HLJEPGAF_00606 8.06e-156 - - - S - - - Protein of unknown function (DUF1361)
HLJEPGAF_00607 2.39e-191 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HLJEPGAF_00608 2.18e-182 ybbR - - S - - - YbbR-like protein
HLJEPGAF_00609 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HLJEPGAF_00610 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HLJEPGAF_00611 8.59e-85 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
HLJEPGAF_00612 1.13e-182 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
HLJEPGAF_00613 3.66e-113 - - - K - - - Acetyltransferase (GNAT) domain
HLJEPGAF_00614 3.3e-202 degV1 - - S - - - DegV family
HLJEPGAF_00615 2.89e-80 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
HLJEPGAF_00616 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
HLJEPGAF_00618 2.76e-141 sip3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HLJEPGAF_00619 0.0 - - - - - - - -
HLJEPGAF_00621 2.13e-209 - - - S - - - Bacterial protein of unknown function (DUF916)
HLJEPGAF_00622 2.16e-142 - - - S - - - Cell surface protein
HLJEPGAF_00623 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HLJEPGAF_00624 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HLJEPGAF_00625 2.14e-155 jag - - S ko:K06346 - ko00000 R3H domain protein
HLJEPGAF_00626 3.75e-305 - - - Q - - - Imidazolonepropionase and related amidohydrolases
HLJEPGAF_00627 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HLJEPGAF_00628 1.55e-158 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLJEPGAF_00629 3.74e-75 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HLJEPGAF_00630 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HLJEPGAF_00631 8.19e-267 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HLJEPGAF_00632 3.82e-51 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
HLJEPGAF_00633 7.24e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HLJEPGAF_00634 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLJEPGAF_00635 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLJEPGAF_00636 5.95e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HLJEPGAF_00637 1.59e-95 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HLJEPGAF_00638 2.69e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HLJEPGAF_00639 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
HLJEPGAF_00640 3.44e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HLJEPGAF_00641 8.77e-317 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HLJEPGAF_00642 4.96e-289 yttB - - EGP - - - Major Facilitator
HLJEPGAF_00643 9e-184 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HLJEPGAF_00644 2.19e-290 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HLJEPGAF_00646 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HLJEPGAF_00647 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HLJEPGAF_00648 6.65e-282 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HLJEPGAF_00649 3.49e-269 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
HLJEPGAF_00650 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
HLJEPGAF_00651 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HLJEPGAF_00652 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HLJEPGAF_00653 8.38e-184 - - - S - - - haloacid dehalogenase-like hydrolase
HLJEPGAF_00654 1.1e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
HLJEPGAF_00655 0.0 trePP 2.4.1.216, 2.4.1.8 GH65 G ko:K00691,ko:K03731 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65 central catalytic domain
HLJEPGAF_00656 3.21e-104 - - - S - - - Pyridoxamine 5'-phosphate oxidase
HLJEPGAF_00657 4.37e-43 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock protein domain
HLJEPGAF_00658 2.54e-50 - - - - - - - -
HLJEPGAF_00660 2.22e-169 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HLJEPGAF_00661 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HLJEPGAF_00662 3.55e-313 yycH - - S - - - YycH protein
HLJEPGAF_00663 3.54e-195 yycI - - S - - - YycH protein
HLJEPGAF_00664 1.71e-200 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
HLJEPGAF_00665 1.5e-253 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
HLJEPGAF_00666 6.08e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HLJEPGAF_00667 3.46e-124 - - - K - - - Bacterial regulatory proteins, tetR family
HLJEPGAF_00668 0.0 - - - C - - - Belongs to the aldehyde dehydrogenase family
HLJEPGAF_00669 6.96e-214 - - - L - - - Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HLJEPGAF_00670 5.97e-157 ung2 - - L - - - Uracil-DNA glycosylase
HLJEPGAF_00671 4.75e-42 pnb - - C - - - nitroreductase
HLJEPGAF_00672 5.63e-86 pnb - - C - - - nitroreductase
HLJEPGAF_00673 4.95e-86 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
HLJEPGAF_00674 1.57e-150 - - - S - - - Elongation factor G-binding protein, N-terminal
HLJEPGAF_00675 0.0 - - - C - - - FMN_bind
HLJEPGAF_00676 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HLJEPGAF_00677 1.46e-204 - - - K - - - LysR family
HLJEPGAF_00678 2.49e-95 - - - C - - - FMN binding
HLJEPGAF_00679 4.48e-98 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HLJEPGAF_00680 4.06e-211 - - - S - - - KR domain
HLJEPGAF_00681 5.74e-204 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
HLJEPGAF_00682 5.07e-157 ydgI - - C - - - Nitroreductase family
HLJEPGAF_00683 0.0 - - - QT - - - PucR C-terminal helix-turn-helix domain
HLJEPGAF_00684 1.56e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
HLJEPGAF_00685 7.63e-249 pva1 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HLJEPGAF_00686 0.0 - - - S - - - Putative threonine/serine exporter
HLJEPGAF_00687 6.86e-175 ptp1 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HLJEPGAF_00688 0.0 hpaH 1.14.14.8, 1.14.14.9 - Q ko:K00483,ko:K16901 ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220 ko00000,ko00001,ko01000 4-hydroxyphenylacetate
HLJEPGAF_00689 1.65e-106 - - - S - - - ASCH
HLJEPGAF_00690 1.25e-164 - - - F - - - glutamine amidotransferase
HLJEPGAF_00691 1.67e-220 - - - K - - - WYL domain
HLJEPGAF_00692 1.63e-152 azoR - - C ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HLJEPGAF_00693 0.0 fusA1 - - J - - - elongation factor G
HLJEPGAF_00694 7.44e-51 - - - S - - - Protein of unknown function
HLJEPGAF_00695 2.7e-79 - - - S - - - Protein of unknown function
HLJEPGAF_00696 8.64e-195 - - - EG - - - EamA-like transporter family
HLJEPGAF_00697 7.65e-121 yfbM - - K - - - FR47-like protein
HLJEPGAF_00698 1.4e-162 - - - S - - - DJ-1/PfpI family
HLJEPGAF_00699 3.14e-230 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
HLJEPGAF_00700 1.92e-67 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HLJEPGAF_00701 5.98e-302 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
HLJEPGAF_00702 9.63e-307 - - - M - - - Glycosyltransferase, group 2 family protein
HLJEPGAF_00703 9.19e-95 - - - S - - - SnoaL-like domain
HLJEPGAF_00704 4.17e-186 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
HLJEPGAF_00705 1.55e-309 - - - P - - - Major Facilitator Superfamily
HLJEPGAF_00706 1.26e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HLJEPGAF_00707 1.44e-282 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HLJEPGAF_00709 9.98e-75 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HLJEPGAF_00710 2.12e-142 ypsA - - S - - - Belongs to the UPF0398 family
HLJEPGAF_00711 3.6e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HLJEPGAF_00712 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
HLJEPGAF_00713 4.64e-228 phnT 3.6.3.30 - P ko:K02010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HLJEPGAF_00714 8.06e-234 ftpB - - P ko:K02012 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HLJEPGAF_00715 0.0 ftpA - - P ko:K02011 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HLJEPGAF_00716 5.32e-109 - - - T - - - Universal stress protein family
HLJEPGAF_00717 1.58e-203 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HLJEPGAF_00718 2.45e-142 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HLJEPGAF_00719 2.32e-238 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HLJEPGAF_00721 9.32e-165 dnaD - - L ko:K02086 - ko00000 Replication initiation and membrane attachment
HLJEPGAF_00722 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
HLJEPGAF_00723 3.1e-289 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HLJEPGAF_00724 2.53e-107 ypmB - - S - - - protein conserved in bacteria
HLJEPGAF_00725 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
HLJEPGAF_00726 1.48e-217 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
HLJEPGAF_00727 1.1e-230 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
HLJEPGAF_00728 2.94e-261 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
HLJEPGAF_00729 8.61e-251 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HLJEPGAF_00730 3.36e-247 galM2 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HLJEPGAF_00731 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HLJEPGAF_00732 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HLJEPGAF_00733 3.24e-155 - - - S - - - Domain of unknown function (DUF4767)
HLJEPGAF_00734 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
HLJEPGAF_00735 3.86e-192 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HLJEPGAF_00736 0.0 - - - E ko:K03294 - ko00000 Amino Acid
HLJEPGAF_00737 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HLJEPGAF_00738 3.23e-58 - - - - - - - -
HLJEPGAF_00739 1.25e-66 - - - - - - - -
HLJEPGAF_00740 5.03e-182 - - - U ko:K10716 - ko00000,ko02000 Ion channel
HLJEPGAF_00741 1.48e-218 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
HLJEPGAF_00742 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HLJEPGAF_00743 8.39e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
HLJEPGAF_00744 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HLJEPGAF_00745 1.06e-53 - - - - - - - -
HLJEPGAF_00746 4e-40 - - - S - - - CsbD-like
HLJEPGAF_00747 2.22e-55 - - - S - - - transglycosylase associated protein
HLJEPGAF_00748 5.79e-21 - - - - - - - -
HLJEPGAF_00749 8.76e-48 - - - - - - - -
HLJEPGAF_00750 1.21e-209 - - - I - - - Diacylglycerol kinase catalytic domain
HLJEPGAF_00751 5.58e-87 - - - S - - - Protein of unknown function (DUF805)
HLJEPGAF_00752 5.28e-100 - - - T - - - Belongs to the universal stress protein A family
HLJEPGAF_00753 6.05e-108 tspO - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 TspO/MBR family
HLJEPGAF_00754 2.05e-55 - - - - - - - -
HLJEPGAF_00755 5.93e-60 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
HLJEPGAF_00756 9.96e-147 - 1.14.99.53 AA10 S ko:K21713 - ko00000,ko01000 Lytic polysaccharide mono-oxygenase, cellulose-degrading
HLJEPGAF_00757 3.2e-37 - - - L ko:K07497 - ko00000 hmm pf00665
HLJEPGAF_00758 6.57e-274 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
HLJEPGAF_00759 2.02e-39 - - - - - - - -
HLJEPGAF_00760 1.48e-71 - - - - - - - -
HLJEPGAF_00761 1.14e-193 - - - O - - - Band 7 protein
HLJEPGAF_00762 0.0 - - - EGP - - - Major Facilitator
HLJEPGAF_00763 4.09e-119 - - - K - - - transcriptional regulator
HLJEPGAF_00764 4.4e-246 rsgA_2 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HLJEPGAF_00765 2.01e-113 ykhA - - I - - - Thioesterase superfamily
HLJEPGAF_00766 7.52e-207 - - - K - - - LysR substrate binding domain
HLJEPGAF_00767 1.48e-161 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HLJEPGAF_00768 5.01e-129 - - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
HLJEPGAF_00769 2.29e-175 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
HLJEPGAF_00770 4.82e-179 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
HLJEPGAF_00771 6.43e-203 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HLJEPGAF_00772 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
HLJEPGAF_00773 1.71e-91 fabZ2 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
HLJEPGAF_00774 2.14e-95 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HLJEPGAF_00775 1.8e-288 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HLJEPGAF_00776 1.26e-162 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
HLJEPGAF_00777 3.47e-215 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
HLJEPGAF_00778 6.16e-48 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HLJEPGAF_00779 1.62e-229 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HLJEPGAF_00780 8.55e-99 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HLJEPGAF_00781 1.62e-229 yneE - - K - - - Transcriptional regulator
HLJEPGAF_00782 6.84e-186 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HLJEPGAF_00784 1.49e-77 - - - S - - - Protein of unknown function (DUF1648)
HLJEPGAF_00785 2.69e-252 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HLJEPGAF_00786 3.38e-274 hipO1 - - E ko:K21613 - ko00000,ko01000,ko01002 Peptidase family M20/M25/M40
HLJEPGAF_00787 1.62e-276 - - - E - - - glutamate:sodium symporter activity
HLJEPGAF_00788 1.95e-88 ybbJ - - K - - - Acetyltransferase (GNAT) family
HLJEPGAF_00789 1.36e-210 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 Zinc-binding dehydrogenase
HLJEPGAF_00790 5.89e-126 entB - - Q - - - Isochorismatase family
HLJEPGAF_00791 4.82e-183 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HLJEPGAF_00792 5.13e-287 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HLJEPGAF_00793 1.57e-142 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
HLJEPGAF_00794 2.41e-165 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
HLJEPGAF_00795 6.03e-226 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HLJEPGAF_00796 8.08e-135 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Peptidase C26
HLJEPGAF_00797 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Anthranilate synthase component I, N terminal region
HLJEPGAF_00799 0.0 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
HLJEPGAF_00800 2.05e-179 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HLJEPGAF_00801 9.06e-112 - - - - - - - -
HLJEPGAF_00802 2.81e-194 - - - M - - - LPXTG-motif cell wall anchor domain protein
HLJEPGAF_00803 3.62e-249 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HLJEPGAF_00804 5.74e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HLJEPGAF_00805 4.66e-131 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
HLJEPGAF_00806 6.84e-167 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
HLJEPGAF_00807 3.46e-242 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
HLJEPGAF_00808 3.8e-176 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HLJEPGAF_00809 2.18e-176 phnE2 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter permease
HLJEPGAF_00810 3.33e-184 phnE1 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HLJEPGAF_00811 2.8e-187 phnX 3.11.1.1 - E ko:K05306 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the HAD-like hydrolase superfamily. PhnX family
HLJEPGAF_00812 5.35e-270 phnW 2.6.1.37 - E ko:K03430 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000,ko01007 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HLJEPGAF_00813 4.95e-246 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HLJEPGAF_00814 1.29e-190 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
HLJEPGAF_00815 2.64e-213 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HLJEPGAF_00816 8.46e-77 yabA - - L - - - Involved in initiation control of chromosome replication
HLJEPGAF_00817 2.33e-239 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HLJEPGAF_00818 1.39e-70 yaaQ - - S - - - Cyclic-di-AMP receptor
HLJEPGAF_00819 1.82e-152 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HLJEPGAF_00820 1.01e-51 yaaL - - S - - - Protein of unknown function (DUF2508)
HLJEPGAF_00821 6.22e-140 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HLJEPGAF_00822 8.34e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HLJEPGAF_00823 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HLJEPGAF_00824 7.57e-119 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HLJEPGAF_00825 6.7e-141 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
HLJEPGAF_00826 8.42e-50 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
HLJEPGAF_00827 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLJEPGAF_00828 2.47e-253 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLJEPGAF_00829 2.37e-140 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HLJEPGAF_00830 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HLJEPGAF_00831 4.82e-86 - - - L - - - nuclease
HLJEPGAF_00832 1.01e-226 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
HLJEPGAF_00833 2.76e-74 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HLJEPGAF_00834 3.72e-105 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HLJEPGAF_00835 2.69e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HLJEPGAF_00836 9.76e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HLJEPGAF_00837 2.81e-202 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HLJEPGAF_00838 1.89e-128 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HLJEPGAF_00839 1e-39 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HLJEPGAF_00840 4.55e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HLJEPGAF_00841 1.12e-130 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Sigma-70 region 2
HLJEPGAF_00842 1.44e-125 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
HLJEPGAF_00843 1.49e-177 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLJEPGAF_00844 1.35e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HLJEPGAF_00845 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HLJEPGAF_00846 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HLJEPGAF_00847 4.91e-265 yacL - - S - - - domain protein
HLJEPGAF_00848 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HLJEPGAF_00849 9.43e-127 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
HLJEPGAF_00850 5.96e-69 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
HLJEPGAF_00851 1.62e-158 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HLJEPGAF_00852 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HLJEPGAF_00853 3.22e-147 zmp2 - - O - - - Zinc-dependent metalloprotease
HLJEPGAF_00854 1.91e-165 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HLJEPGAF_00855 1.22e-226 - - - EG - - - EamA-like transporter family
HLJEPGAF_00856 3.06e-214 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
HLJEPGAF_00857 5.37e-233 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HLJEPGAF_00858 1.05e-172 accA1 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
HLJEPGAF_00859 1.49e-183 accD1 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HLJEPGAF_00860 1.7e-315 accC1 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase C-terminal domain
HLJEPGAF_00861 9.24e-85 accB1 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin-requiring enzyme
HLJEPGAF_00862 3.15e-229 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HLJEPGAF_00863 4.5e-113 manX 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HLJEPGAF_00864 4.16e-93 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HLJEPGAF_00865 0.0 levR - - K - - - Sigma-54 interaction domain
HLJEPGAF_00866 9.05e-85 manO - - S - - - Domain of unknown function (DUF956)
HLJEPGAF_00867 4.22e-216 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
HLJEPGAF_00868 4.51e-172 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
HLJEPGAF_00869 6.46e-218 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HLJEPGAF_00870 1.53e-195 - - - G - - - Peptidase_C39 like family
HLJEPGAF_00872 1.9e-198 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HLJEPGAF_00873 1.71e-302 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
HLJEPGAF_00874 3.09e-106 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
HLJEPGAF_00875 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
HLJEPGAF_00876 2.57e-94 - - - - ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 -
HLJEPGAF_00877 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HLJEPGAF_00878 1.51e-196 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HLJEPGAF_00879 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HLJEPGAF_00880 5.44e-175 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HLJEPGAF_00881 5.41e-160 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
HLJEPGAF_00882 2.92e-280 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
HLJEPGAF_00883 2.18e-174 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HLJEPGAF_00884 1.06e-195 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
HLJEPGAF_00885 1.59e-247 ysdE - - P - - - Citrate transporter
HLJEPGAF_00886 3.1e-212 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
HLJEPGAF_00887 1.38e-71 - - - S - - - Cupin domain
HLJEPGAF_00888 9.02e-66 - - - S - - - Cupin 2, conserved barrel domain protein
HLJEPGAF_00892 1.75e-193 - - - S - - - Calcineurin-like phosphoesterase
HLJEPGAF_00893 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
HLJEPGAF_00894 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HLJEPGAF_00895 1.56e-46 ykuJ - - S - - - Protein of unknown function (DUF1797)
HLJEPGAF_00896 3.91e-289 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HLJEPGAF_00897 2.29e-292 dacA2 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HLJEPGAF_00898 2.16e-241 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HLJEPGAF_00899 2.04e-254 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HLJEPGAF_00900 1.41e-285 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HLJEPGAF_00901 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HLJEPGAF_00902 1.24e-52 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
HLJEPGAF_00903 5.6e-41 - - - - - - - -
HLJEPGAF_00904 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
HLJEPGAF_00905 3.29e-95 - - - L - - - Integrase
HLJEPGAF_00906 3.4e-85 - - - K - - - Winged helix DNA-binding domain
HLJEPGAF_00907 5.67e-231 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HLJEPGAF_00908 4.86e-258 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HLJEPGAF_00909 3.59e-241 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLJEPGAF_00910 3.44e-210 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLJEPGAF_00911 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HLJEPGAF_00912 3.85e-76 ywjH - - S - - - Protein of unknown function (DUF1634)
HLJEPGAF_00913 1.01e-172 - - - S ko:K07090 - ko00000 membrane transporter protein
HLJEPGAF_00914 1.36e-208 lysR5 - - K - - - LysR substrate binding domain
HLJEPGAF_00915 1.01e-250 - - - M - - - MucBP domain
HLJEPGAF_00916 0.0 - - - - - - - -
HLJEPGAF_00917 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HLJEPGAF_00918 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
HLJEPGAF_00919 1.22e-218 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
HLJEPGAF_00920 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HLJEPGAF_00921 7.89e-290 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
HLJEPGAF_00922 6.04e-94 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
HLJEPGAF_00923 1.13e-257 yueF - - S - - - AI-2E family transporter
HLJEPGAF_00924 7.3e-216 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HLJEPGAF_00925 7.17e-39 - - - S - - - Antitoxin component of a toxin-antitoxin (TA) module
HLJEPGAF_00926 3.97e-64 - - - K - - - sequence-specific DNA binding
HLJEPGAF_00927 1.94e-170 lytE - - M - - - NlpC/P60 family
HLJEPGAF_00928 6.62e-138 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
HLJEPGAF_00929 1.01e-181 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
HLJEPGAF_00930 1.34e-168 - - - - - - - -
HLJEPGAF_00931 1.68e-131 - - - K - - - DNA-templated transcription, initiation
HLJEPGAF_00932 3.31e-35 - - - - - - - -
HLJEPGAF_00933 1.95e-41 - - - - - - - -
HLJEPGAF_00934 1.04e-45 - - - S - - - Protein of unknown function (DUF2922)
HLJEPGAF_00935 9.02e-70 - - - - - - - -
HLJEPGAF_00937 3.98e-169 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HLJEPGAF_00938 1.95e-197 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
HLJEPGAF_00939 3.34e-267 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HLJEPGAF_00940 3.3e-281 pbpX - - V - - - Beta-lactamase
HLJEPGAF_00941 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HLJEPGAF_00942 8.31e-139 - - - - - - - -
HLJEPGAF_00943 7.62e-97 - - - - - - - -
HLJEPGAF_00945 3.21e-209 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HLJEPGAF_00946 3.15e-313 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLJEPGAF_00947 3.93e-99 - - - T - - - Universal stress protein family
HLJEPGAF_00949 5.62e-316 yfmL - - L - - - DEAD DEAH box helicase
HLJEPGAF_00950 7.89e-245 mocA - - S - - - Oxidoreductase
HLJEPGAF_00951 6.22e-43 cspP - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
HLJEPGAF_00952 7.34e-83 - - - S - - - Domain of unknown function (DUF4828)
HLJEPGAF_00953 2.22e-185 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HLJEPGAF_00954 5.63e-196 gntR - - K - - - rpiR family
HLJEPGAF_00955 2.87e-215 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HLJEPGAF_00956 7.06e-307 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLJEPGAF_00957 0.0 yfgQ - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
HLJEPGAF_00958 2.26e-129 yobS - - K - - - Bacterial regulatory proteins, tetR family
HLJEPGAF_00959 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HLJEPGAF_00960 1.59e-242 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
HLJEPGAF_00961 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLJEPGAF_00962 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HLJEPGAF_00963 5.11e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLJEPGAF_00964 9.48e-263 camS - - S - - - sex pheromone
HLJEPGAF_00965 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HLJEPGAF_00966 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HLJEPGAF_00967 1.39e-279 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HLJEPGAF_00968 1.13e-120 yebE - - S - - - UPF0316 protein
HLJEPGAF_00969 2.01e-134 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HLJEPGAF_00970 1.97e-145 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
HLJEPGAF_00971 7.78e-235 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HLJEPGAF_00972 7.8e-58 - - - K - - - Helix-turn-helix domain
HLJEPGAF_00973 1.08e-71 - - - - - - - -
HLJEPGAF_00974 1.66e-96 - - - - - - - -
HLJEPGAF_00975 6.67e-30 - - - L ko:K07497 - ko00000 hmm pf00665
HLJEPGAF_00976 8.56e-38 - - - L ko:K07497 - ko00000 hmm pf00665
HLJEPGAF_00977 9.16e-61 - - - L - - - Helix-turn-helix domain
HLJEPGAF_00979 3.56e-171 spoVK - - O ko:K06413 - ko00000 ATPase family associated with various cellular activities (AAA)
HLJEPGAF_00981 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HLJEPGAF_00982 1.22e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
HLJEPGAF_00983 8.45e-211 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
HLJEPGAF_00984 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HLJEPGAF_00985 4.51e-143 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
HLJEPGAF_00986 4.16e-227 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
HLJEPGAF_00987 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
HLJEPGAF_00988 2.07e-161 gpm2 - - G - - - Phosphoglycerate mutase family
HLJEPGAF_00989 1.35e-165 pgm3 - - G - - - Phosphoglycerate mutase family
HLJEPGAF_00990 1.61e-36 - - - - - - - -
HLJEPGAF_00991 3.5e-64 sugE - - U ko:K11741 - ko00000,ko02000 Multidrug resistance protein
HLJEPGAF_00992 4.6e-102 rppH3 - - F - - - NUDIX domain
HLJEPGAF_00993 5.95e-300 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HLJEPGAF_00994 1.81e-128 - - - K - - - Bacterial regulatory proteins, tetR family
HLJEPGAF_00995 2.93e-109 - - - S ko:K07090 - ko00000 membrane transporter protein
HLJEPGAF_00996 3.22e-269 - - - EGP - - - Major Facilitator Superfamily
HLJEPGAF_00997 7.26e-92 - - - K - - - MarR family
HLJEPGAF_00998 8.87e-191 - - - S - - - Sulfite exporter TauE/SafE
HLJEPGAF_00999 6.26e-96 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HLJEPGAF_01000 9.38e-317 steT - - E ko:K03294 - ko00000 amino acid
HLJEPGAF_01001 4.87e-180 - 3.5.1.105 - G ko:K03478 - ko00000,ko01000 YdjC-like protein
HLJEPGAF_01002 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HLJEPGAF_01003 7.77e-197 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HLJEPGAF_01004 7.04e-108 - - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HLJEPGAF_01005 1.27e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HLJEPGAF_01006 3.14e-140 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HLJEPGAF_01007 3.39e-190 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HLJEPGAF_01008 2.3e-172 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HLJEPGAF_01010 1.28e-54 - - - - - - - -
HLJEPGAF_01011 2.07e-217 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLJEPGAF_01012 1.05e-234 aspC 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HLJEPGAF_01013 1.94e-95 gph1 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant
HLJEPGAF_01014 1.01e-188 - - - - - - - -
HLJEPGAF_01015 8.84e-18 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
HLJEPGAF_01016 2.02e-106 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HLJEPGAF_01017 2.45e-134 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
HLJEPGAF_01018 1.48e-27 - - - - - - - -
HLJEPGAF_01019 7.48e-96 - - - F - - - Nudix hydrolase
HLJEPGAF_01020 1.23e-189 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
HLJEPGAF_01021 6.12e-115 - - - - - - - -
HLJEPGAF_01022 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
HLJEPGAF_01023 3.8e-61 - - - - - - - -
HLJEPGAF_01024 1.55e-89 - - - O - - - OsmC-like protein
HLJEPGAF_01025 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HLJEPGAF_01026 0.0 oatA - - I - - - Acyltransferase
HLJEPGAF_01027 5.01e-229 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HLJEPGAF_01028 3.45e-231 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HLJEPGAF_01029 0.0 pox2 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HLJEPGAF_01030 5.47e-198 ribC1 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HLJEPGAF_01031 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HLJEPGAF_01032 1.79e-287 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HLJEPGAF_01033 1.36e-27 - - - - - - - -
HLJEPGAF_01034 3.68e-107 - - - K - - - Transcriptional regulator
HLJEPGAF_01035 7.8e-196 licD - - M ko:K07271 - ko00000,ko01000 LicD family
HLJEPGAF_01036 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HLJEPGAF_01037 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HLJEPGAF_01038 4.45e-226 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HLJEPGAF_01039 3.49e-315 - - - EGP - - - Major Facilitator
HLJEPGAF_01040 1.71e-116 - - - V - - - VanZ like family
HLJEPGAF_01041 3.88e-46 - - - - - - - -
HLJEPGAF_01042 5.45e-94 spx1 - - P ko:K16509 - ko00000 ArsC family
HLJEPGAF_01044 6.37e-186 - - - - - - - -
HLJEPGAF_01045 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HLJEPGAF_01046 7.08e-197 - - - G ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
HLJEPGAF_01047 2.87e-168 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
HLJEPGAF_01048 2.49e-95 - - - - - - - -
HLJEPGAF_01049 3.38e-70 - - - - - - - -
HLJEPGAF_01050 1.46e-263 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HLJEPGAF_01051 1.21e-135 - - - K - - - Bacterial regulatory proteins, tetR family
HLJEPGAF_01052 8.04e-190 - 3.1.3.23 - S ko:K07757 - ko00000,ko01000 Sucrose-6F-phosphate phosphohydrolase
HLJEPGAF_01053 5.44e-159 - - - T - - - EAL domain
HLJEPGAF_01054 0.0 - - - P - - - Sodium:sulfate symporter transmembrane region
HLJEPGAF_01055 0.0 astA 2.8.2.22 - M ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
HLJEPGAF_01056 2.54e-225 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain
HLJEPGAF_01057 3.72e-145 cysC 2.7.1.25 - F ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
HLJEPGAF_01058 7.32e-292 sat 2.7.7.4 - H ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HLJEPGAF_01059 0.0 - - - S - - - Protein conserved in bacteria
HLJEPGAF_01060 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HLJEPGAF_01061 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HLJEPGAF_01062 8.01e-77 - - - S - - - Protein of unknown function (DUF1516)
HLJEPGAF_01063 4.91e-117 gtcA1 - - S - - - Teichoic acid glycosylation protein
HLJEPGAF_01064 3.89e-237 - - - - - - - -
HLJEPGAF_01065 9.03e-16 - - - - - - - -
HLJEPGAF_01066 4.29e-87 - - - - - - - -
HLJEPGAF_01069 0.0 uvrA2 - - L - - - ABC transporter
HLJEPGAF_01070 7.12e-62 - - - - - - - -
HLJEPGAF_01071 8.82e-119 - - - - - - - -
HLJEPGAF_01072 2.2e-111 ohrR - - K ko:K18906 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
HLJEPGAF_01073 1.23e-145 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
HLJEPGAF_01074 4.56e-78 - - - - - - - -
HLJEPGAF_01075 5.37e-74 - - - - - - - -
HLJEPGAF_01076 9.01e-179 agrA - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HLJEPGAF_01077 2.08e-283 pltK 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HLJEPGAF_01078 7.83e-140 - - - - - - - -
HLJEPGAF_01079 1.89e-189 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HLJEPGAF_01080 9.36e-205 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HLJEPGAF_01081 1.64e-151 - - - GM - - - NAD(P)H-binding
HLJEPGAF_01082 5.2e-85 - - - K - - - helix_turn_helix, mercury resistance
HLJEPGAF_01083 6.96e-198 mrsA1 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HLJEPGAF_01085 2.57e-226 - - - K ko:K01990 - ko00000,ko00002,ko02000 LytTr DNA-binding domain
HLJEPGAF_01086 3.06e-201 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HLJEPGAF_01087 3.34e-160 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
HLJEPGAF_01089 3e-315 XK27_06930 - - V ko:K01421 - ko00000 domain protein
HLJEPGAF_01090 3.55e-72 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HLJEPGAF_01091 2.07e-155 dgk2 - - F - - - deoxynucleoside kinase
HLJEPGAF_01092 5.01e-229 ugpB - - G ko:K05813 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HLJEPGAF_01093 3.05e-193 ugpE - - G ko:K05815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HLJEPGAF_01094 1.13e-221 ugpA - - U ko:K02025,ko:K05814 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HLJEPGAF_01095 2.92e-258 ugpC 3.6.3.20 - E ko:K05816,ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the ABC transporter superfamily
HLJEPGAF_01096 2.16e-109 - - - T - - - Belongs to the universal stress protein A family
HLJEPGAF_01097 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
HLJEPGAF_01098 3.03e-193 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HLJEPGAF_01099 5.04e-176 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HLJEPGAF_01100 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HLJEPGAF_01101 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HLJEPGAF_01102 3.58e-161 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
HLJEPGAF_01103 3.03e-122 mraW1 - - J - - - Putative rRNA methylase
HLJEPGAF_01104 9.32e-40 - - - - - - - -
HLJEPGAF_01105 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HLJEPGAF_01106 0.0 tagE2 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HLJEPGAF_01107 0.0 - - - S - - - Pfam Methyltransferase
HLJEPGAF_01108 1.21e-185 - - - N - - - Cell shape-determining protein MreB
HLJEPGAF_01109 1.37e-60 - - - N - - - Cell shape-determining protein MreB
HLJEPGAF_01110 0.0 mdr - - EGP - - - Major Facilitator
HLJEPGAF_01111 2.78e-273 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HLJEPGAF_01112 3.35e-157 - - - - - - - -
HLJEPGAF_01113 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HLJEPGAF_01114 2.75e-216 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
HLJEPGAF_01115 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HLJEPGAF_01116 6.21e-241 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
HLJEPGAF_01117 2.19e-291 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HLJEPGAF_01119 3.47e-134 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
HLJEPGAF_01120 2.98e-46 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
HLJEPGAF_01121 1.58e-122 - - - K - - - Acetyltransferase (GNAT) domain
HLJEPGAF_01122 1.25e-124 - - - - - - - -
HLJEPGAF_01123 6.36e-237 - - - P ko:K06901 - ko00000,ko02000 secondary active sulfate transmembrane transporter activity
HLJEPGAF_01124 3.26e-119 - 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Phosphoribosyl transferase domain
HLJEPGAF_01135 2.8e-63 - - - - - - - -
HLJEPGAF_01136 1.23e-75 - - - - - - - -
HLJEPGAF_01137 1.86e-210 - - - - - - - -
HLJEPGAF_01138 1.4e-95 - - - K - - - Transcriptional regulator
HLJEPGAF_01139 0.0 pepF2 - - E - - - Oligopeptidase F
HLJEPGAF_01140 8.94e-221 ybcH - - D ko:K06889 - ko00000 Alpha beta
HLJEPGAF_01141 7.2e-61 - - - S - - - Enterocin A Immunity
HLJEPGAF_01142 8.34e-86 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
HLJEPGAF_01143 1.01e-161 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HLJEPGAF_01144 2.66e-172 - - - - - - - -
HLJEPGAF_01145 9.38e-139 pncA - - Q - - - Isochorismatase family
HLJEPGAF_01146 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HLJEPGAF_01147 0.0 nhaP2 - - P ko:K03316 - ko00000 Sodium proton antiporter
HLJEPGAF_01148 8.97e-253 yhhX - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
HLJEPGAF_01149 2.48e-227 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HLJEPGAF_01150 5.91e-150 - - - K - - - Helix-turn-helix domain, rpiR family
HLJEPGAF_01151 1.48e-201 ccpB - - K - - - lacI family
HLJEPGAF_01152 2.2e-157 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HLJEPGAF_01153 3.68e-203 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HLJEPGAF_01154 5.02e-228 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
HLJEPGAF_01155 3e-127 - - - C - - - Nitroreductase family
HLJEPGAF_01156 6.04e-217 - - - S - - - Polyphosphate kinase 2 (PPK2)
HLJEPGAF_01157 2.14e-183 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HLJEPGAF_01158 2.71e-234 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
HLJEPGAF_01159 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
HLJEPGAF_01160 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HLJEPGAF_01161 6.05e-98 yjcF - - S - - - Acetyltransferase (GNAT) domain
HLJEPGAF_01162 1.78e-279 - - - M - - - domain protein
HLJEPGAF_01163 6.32e-67 - - - M - - - domain protein
HLJEPGAF_01164 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
HLJEPGAF_01165 1.06e-145 - - - S - - - Protein of unknown function (DUF1211)
HLJEPGAF_01166 1.45e-46 - - - - - - - -
HLJEPGAF_01167 5.48e-236 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HLJEPGAF_01168 1.97e-254 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HLJEPGAF_01169 4.54e-126 - - - J - - - glyoxalase III activity
HLJEPGAF_01170 1.01e-189 - - - GM - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HLJEPGAF_01171 4.73e-118 rmeB - - K - - - transcriptional regulator, MerR family
HLJEPGAF_01172 6.7e-74 - - - S - - - Domain of unknown function (DU1801)
HLJEPGAF_01173 7.28e-213 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
HLJEPGAF_01174 3.72e-283 ysaA - - V - - - RDD family
HLJEPGAF_01175 4.54e-208 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphate phosphatase, HisJ
HLJEPGAF_01176 2.3e-275 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HLJEPGAF_01177 1.69e-151 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HLJEPGAF_01178 7.8e-299 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HLJEPGAF_01179 2.46e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
HLJEPGAF_01180 2.23e-142 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HLJEPGAF_01181 5.62e-165 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HLJEPGAF_01182 1.27e-172 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HLJEPGAF_01183 6.12e-78 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HLJEPGAF_01184 1.07e-68 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
HLJEPGAF_01185 1.9e-258 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HLJEPGAF_01186 2.47e-125 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HLJEPGAF_01187 1.18e-175 yceF - - P ko:K05794 - ko00000 membrane
HLJEPGAF_01188 9.51e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
HLJEPGAF_01189 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
HLJEPGAF_01190 1.32e-178 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HLJEPGAF_01191 6.03e-196 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HLJEPGAF_01192 9.31e-225 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HLJEPGAF_01193 1.53e-213 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
HLJEPGAF_01194 6.08e-312 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HLJEPGAF_01195 6.83e-292 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
HLJEPGAF_01196 3.45e-209 - - - S - - - Uncharacterised protein, DegV family COG1307
HLJEPGAF_01197 1.31e-242 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HLJEPGAF_01198 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HLJEPGAF_01199 2.64e-61 - - - - - - - -
HLJEPGAF_01200 2.35e-106 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLJEPGAF_01201 4.75e-157 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HLJEPGAF_01202 1.13e-171 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
HLJEPGAF_01203 4.87e-156 vex2 - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HLJEPGAF_01204 4.32e-294 vex3 - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
HLJEPGAF_01205 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
HLJEPGAF_01206 1.96e-137 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
HLJEPGAF_01207 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
HLJEPGAF_01208 1.17e-135 - - - K - - - transcriptional regulator
HLJEPGAF_01209 2.04e-158 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
HLJEPGAF_01210 1.49e-63 - - - - - - - -
HLJEPGAF_01211 0.0 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
HLJEPGAF_01212 5.06e-236 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HLJEPGAF_01213 2.87e-56 - - - - - - - -
HLJEPGAF_01214 1.6e-73 - - - - - - - -
HLJEPGAF_01215 6.86e-311 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLJEPGAF_01216 2.78e-167 yidA - - K - - - Helix-turn-helix domain, rpiR family
HLJEPGAF_01217 9.86e-65 - - - - - - - -
HLJEPGAF_01218 2.58e-163 rrp2 - - K - - - Transcriptional regulatory protein, C terminal
HLJEPGAF_01219 1.72e-315 hpk2 - - T - - - Histidine kinase
HLJEPGAF_01220 2.2e-86 - - - K - - - helix_turn_helix, mercury resistance
HLJEPGAF_01221 0.0 ydiC - - EGP - - - Major Facilitator
HLJEPGAF_01222 3.13e-55 - - - - - - - -
HLJEPGAF_01223 6.37e-52 - - - - - - - -
HLJEPGAF_01224 4.5e-150 - - - - - - - -
HLJEPGAF_01225 4.02e-301 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HLJEPGAF_01226 8.62e-155 - - - K - - - Bacterial regulatory proteins, tetR family
HLJEPGAF_01227 8.9e-96 ywnA - - K - - - Transcriptional regulator
HLJEPGAF_01228 2.73e-92 - - - - - - - -
HLJEPGAF_01229 3.37e-129 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HLJEPGAF_01230 0.0 tagF2 2.7.8.12 - H ko:K09809 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HLJEPGAF_01231 5.71e-306 tagB 2.7.8.12, 2.7.8.45 - M ko:K09809,ko:K21591 - ko00000,ko01000 glycerophosphotransferase
HLJEPGAF_01232 1.21e-94 tagD 2.7.7.15, 2.7.7.39 - IM ko:K00968,ko:K00980 ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231 ko00000,ko00001,ko00002,ko01000 Glycerol-3-phosphate cytidylyltransferase
HLJEPGAF_01233 2.6e-185 - - - - - - - -
HLJEPGAF_01234 0.0 pts5ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HLJEPGAF_01235 0.0 pts4ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HLJEPGAF_01236 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HLJEPGAF_01237 1.68e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
HLJEPGAF_01238 6.35e-56 - - - - - - - -
HLJEPGAF_01239 7.55e-58 - - - S - - - Protein of unknown function (DUF2089)
HLJEPGAF_01240 1.27e-181 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
HLJEPGAF_01241 6.72e-203 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
HLJEPGAF_01242 2.52e-209 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HLJEPGAF_01243 7.87e-266 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HLJEPGAF_01244 2.13e-124 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
HLJEPGAF_01245 1.82e-126 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
HLJEPGAF_01246 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
HLJEPGAF_01247 2.41e-106 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
HLJEPGAF_01248 1.73e-89 - - - - - - - -
HLJEPGAF_01249 2.37e-123 - - - - - - - -
HLJEPGAF_01250 5.92e-67 - - - - - - - -
HLJEPGAF_01251 4.81e-76 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HLJEPGAF_01252 1.21e-111 - - - - - - - -
HLJEPGAF_01253 1.76e-280 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
HLJEPGAF_01254 5.33e-103 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLJEPGAF_01255 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
HLJEPGAF_01256 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HLJEPGAF_01257 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HLJEPGAF_01258 7.02e-126 - - - K - - - Helix-turn-helix domain
HLJEPGAF_01259 3.91e-283 - - - C - - - FAD dependent oxidoreductase
HLJEPGAF_01260 1.82e-220 - - - P - - - Major Facilitator Superfamily
HLJEPGAF_01261 3.16e-170 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HLJEPGAF_01262 2.32e-43 ygzD - - K ko:K07729 - ko00000,ko03000 Transcriptional
HLJEPGAF_01263 1.2e-91 - - - - - - - -
HLJEPGAF_01264 1.05e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HLJEPGAF_01265 5.3e-202 dkgB - - S - - - reductase
HLJEPGAF_01266 6.07e-117 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
HLJEPGAF_01267 2.02e-131 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC transporter permease
HLJEPGAF_01268 0.0 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HLJEPGAF_01269 1.5e-150 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
HLJEPGAF_01270 2.34e-242 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HLJEPGAF_01271 4.15e-153 - - - I - - - phosphatase
HLJEPGAF_01272 3.88e-198 - - - I - - - alpha/beta hydrolase fold
HLJEPGAF_01273 3.03e-129 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HLJEPGAF_01274 5.68e-117 - - - K - - - Transcriptional regulator
HLJEPGAF_01275 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HLJEPGAF_01276 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
HLJEPGAF_01277 7.48e-153 dacB 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
HLJEPGAF_01278 1.11e-148 dgk2 - - F - - - deoxynucleoside kinase
HLJEPGAF_01279 1.62e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HLJEPGAF_01286 9.78e-102 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
HLJEPGAF_01287 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HLJEPGAF_01288 1.16e-140 - - - K - - - Bacterial regulatory proteins, tetR family
HLJEPGAF_01289 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLJEPGAF_01290 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLJEPGAF_01291 1.48e-149 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
HLJEPGAF_01292 4.19e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HLJEPGAF_01293 1.19e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HLJEPGAF_01294 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HLJEPGAF_01295 4.46e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HLJEPGAF_01296 1.24e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HLJEPGAF_01297 9.83e-141 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HLJEPGAF_01298 2.27e-59 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HLJEPGAF_01299 6.61e-193 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HLJEPGAF_01300 1.85e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HLJEPGAF_01301 3.59e-69 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HLJEPGAF_01302 5.46e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HLJEPGAF_01303 8.29e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HLJEPGAF_01304 1.11e-33 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HLJEPGAF_01305 1.96e-54 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HLJEPGAF_01306 2.98e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HLJEPGAF_01307 4.1e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HLJEPGAF_01308 3.53e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HLJEPGAF_01309 4.99e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HLJEPGAF_01310 2.14e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HLJEPGAF_01311 1.75e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HLJEPGAF_01312 5.32e-109 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HLJEPGAF_01313 8.44e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
HLJEPGAF_01314 1.32e-91 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HLJEPGAF_01315 5.95e-300 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HLJEPGAF_01316 1.84e-160 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HLJEPGAF_01317 9.87e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HLJEPGAF_01318 9.65e-79 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HLJEPGAF_01319 7.71e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HLJEPGAF_01320 2.19e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLJEPGAF_01321 7.76e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HLJEPGAF_01322 1.02e-233 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HLJEPGAF_01323 1.41e-122 hepA 2.5.1.30 - S ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase component I
HLJEPGAF_01324 4.42e-111 - - - S - - - NusG domain II
HLJEPGAF_01325 0.0 ndh 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HLJEPGAF_01326 3.19e-194 - - - S - - - FMN_bind
HLJEPGAF_01327 3.08e-264 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HLJEPGAF_01328 1.98e-197 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLJEPGAF_01329 2.01e-211 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLJEPGAF_01330 2.29e-182 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLJEPGAF_01331 3.06e-194 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HLJEPGAF_01332 4.58e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HLJEPGAF_01333 8.98e-86 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HLJEPGAF_01334 8.51e-210 yitS - - S - - - Uncharacterised protein, DegV family COG1307
HLJEPGAF_01335 1.68e-221 - - - S - - - Membrane
HLJEPGAF_01336 9.14e-38 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
HLJEPGAF_01337 2.99e-208 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
HLJEPGAF_01338 0.0 tkt2 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HLJEPGAF_01339 1.65e-211 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HLJEPGAF_01340 3.3e-235 aroF 2.5.1.54 - E ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 DAHP synthetase I family
HLJEPGAF_01341 1.33e-255 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HLJEPGAF_01343 1.49e-281 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HLJEPGAF_01344 1.51e-69 yitW - - S - - - Iron-sulfur cluster assembly protein
HLJEPGAF_01345 1.41e-147 - 4.2.1.2, 4.2.1.32 - C ko:K01676,ko:K03780 ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible hydration of fumarate to (S)- malate
HLJEPGAF_01346 4.28e-225 ttdA 4.2.1.32 - C ko:K03779 ko00630,map00630 ko00000,ko00001,ko01000 Fumarate hydratase (Fumerase)
HLJEPGAF_01347 6.07e-252 - - - K - - - Helix-turn-helix domain
HLJEPGAF_01348 3.16e-196 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HLJEPGAF_01349 2.04e-170 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HLJEPGAF_01350 1.76e-180 mtsB - - U ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
HLJEPGAF_01351 4.26e-222 mntA - - P ko:K19975,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HLJEPGAF_01352 1.18e-66 - - - - - - - -
HLJEPGAF_01353 1.01e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
HLJEPGAF_01354 4.82e-165 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HLJEPGAF_01355 1.81e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HLJEPGAF_01356 5.41e-77 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HLJEPGAF_01357 2.03e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HLJEPGAF_01358 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HLJEPGAF_01359 9.14e-213 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HLJEPGAF_01360 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HLJEPGAF_01361 5.95e-74 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HLJEPGAF_01362 4.85e-314 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HLJEPGAF_01363 1.68e-132 - - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HLJEPGAF_01364 1.44e-230 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
HLJEPGAF_01365 1.52e-57 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
HLJEPGAF_01366 1.04e-45 - - - S - - - Protein of unknown function (DUF2969)
HLJEPGAF_01367 2.15e-280 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HLJEPGAF_01368 3.2e-64 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
HLJEPGAF_01369 2.24e-239 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HLJEPGAF_01370 2.1e-151 metI - - U ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HLJEPGAF_01371 8.69e-191 metQ - - M ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HLJEPGAF_01372 3.34e-215 hicD3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HLJEPGAF_01373 3.26e-227 - - - S - - - Protein of unknown function (DUF2785)
HLJEPGAF_01374 7.55e-242 - 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HLJEPGAF_01375 6.54e-273 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HLJEPGAF_01376 0.0 glpQ3 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
HLJEPGAF_01377 4.7e-207 - - - K - - - Helix-turn-helix XRE-family like proteins
HLJEPGAF_01378 1.1e-258 bla2 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
HLJEPGAF_01379 2.37e-107 uspA - - T - - - universal stress protein
HLJEPGAF_01380 1.34e-52 - - - - - - - -
HLJEPGAF_01381 7.27e-303 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
HLJEPGAF_01382 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
HLJEPGAF_01383 9.17e-59 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HLJEPGAF_01384 1.24e-139 - - - S - - - Protein of unknown function (DUF1648)
HLJEPGAF_01385 1.63e-104 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
HLJEPGAF_01386 4.02e-145 yktB - - S - - - Belongs to the UPF0637 family
HLJEPGAF_01387 2.15e-137 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HLJEPGAF_01388 7.5e-105 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
HLJEPGAF_01389 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HLJEPGAF_01391 2.59e-277 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HLJEPGAF_01392 8.93e-291 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HLJEPGAF_01393 1.57e-299 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
HLJEPGAF_01394 3.56e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HLJEPGAF_01395 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HLJEPGAF_01396 5.62e-316 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HLJEPGAF_01397 1.15e-150 radC - - L ko:K03630 - ko00000 DNA repair protein
HLJEPGAF_01398 1.74e-211 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
HLJEPGAF_01399 3.76e-184 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HLJEPGAF_01400 9.47e-115 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
HLJEPGAF_01401 3.81e-150 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HLJEPGAF_01402 1.23e-187 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
HLJEPGAF_01403 1.89e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HLJEPGAF_01404 3.17e-149 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HLJEPGAF_01405 2.61e-199 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
HLJEPGAF_01406 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HLJEPGAF_01407 3.55e-296 ymfF - - S - - - Peptidase M16 inactive domain protein
HLJEPGAF_01408 0.0 ymfH - - S - - - Peptidase M16
HLJEPGAF_01409 5.74e-172 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
HLJEPGAF_01410 1.92e-127 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HLJEPGAF_01411 3.83e-295 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
HLJEPGAF_01412 2.43e-264 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HLJEPGAF_01413 6.57e-291 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HLJEPGAF_01414 6.18e-197 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 YmdB-like protein
HLJEPGAF_01415 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HLJEPGAF_01416 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HLJEPGAF_01417 9.01e-215 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HLJEPGAF_01418 7.76e-181 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
HLJEPGAF_01419 2.38e-99 - - - - - - - -
HLJEPGAF_01420 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HLJEPGAF_01421 2.4e-180 - - - - - - - -
HLJEPGAF_01422 4.07e-05 - - - - - - - -
HLJEPGAF_01423 5.66e-184 ant1 2.7.7.47 - H ko:K00984 - ko00000,ko01000,ko01504 Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HLJEPGAF_01424 1.67e-54 - - - - - - - -
HLJEPGAF_01425 4.29e-166 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HLJEPGAF_01426 9.79e-192 - - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HLJEPGAF_01427 1.84e-235 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
HLJEPGAF_01428 1.15e-155 rcfB - - K - - - Crp-like helix-turn-helix domain
HLJEPGAF_01429 7.9e-306 larA 5.1.2.1 - S ko:K22373 ko00620,map00620 ko00000,ko00001,ko01000 Domain of unknown function (DUF2088)
HLJEPGAF_01430 1.78e-160 larB - - S ko:K06898 - ko00000 AIR carboxylase
HLJEPGAF_01431 3.58e-174 larC 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HLJEPGAF_01432 1.19e-170 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HLJEPGAF_01433 2.6e-193 larE - - S ko:K06864 - ko00000 NAD synthase
HLJEPGAF_01434 7.11e-227 - - - C - - - Zinc-binding dehydrogenase
HLJEPGAF_01435 1.87e-175 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HLJEPGAF_01436 7.44e-192 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HLJEPGAF_01437 1.61e-144 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HLJEPGAF_01438 1.45e-261 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
HLJEPGAF_01439 2.39e-174 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
HLJEPGAF_01440 0.0 - - - L - - - HIRAN domain
HLJEPGAF_01441 1.24e-109 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
HLJEPGAF_01442 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
HLJEPGAF_01443 5.18e-159 - - - - - - - -
HLJEPGAF_01444 2.07e-191 - - - I - - - Alpha/beta hydrolase family
HLJEPGAF_01445 0.0 pacL1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HLJEPGAF_01446 1.34e-183 - - - F - - - Phosphorylase superfamily
HLJEPGAF_01447 2.92e-38 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
HLJEPGAF_01448 1.72e-142 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
HLJEPGAF_01449 1.27e-98 - - - K - - - Transcriptional regulator
HLJEPGAF_01450 3.99e-96 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HLJEPGAF_01451 5.51e-106 - - - S - - - Protein of unknown function (DUF3021)
HLJEPGAF_01452 5.38e-290 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
HLJEPGAF_01453 3.98e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HLJEPGAF_01454 2.79e-274 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
HLJEPGAF_01456 2.16e-204 morA - - S - - - reductase
HLJEPGAF_01457 8.21e-213 - 1.1.1.65 - C ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 ko00000,ko00001,ko01000 Aldo keto reductase
HLJEPGAF_01458 1.92e-106 - - - F - - - Nucleoside 2-deoxyribosyltransferase like
HLJEPGAF_01459 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
HLJEPGAF_01460 7.45e-103 - - - - - - - -
HLJEPGAF_01461 0.0 - - - - - - - -
HLJEPGAF_01462 6.49e-268 - - - C - - - Oxidoreductase
HLJEPGAF_01463 3.28e-193 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
HLJEPGAF_01464 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HLJEPGAF_01465 2.57e-128 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
HLJEPGAF_01467 4.37e-167 - - - K ko:K03492 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
HLJEPGAF_01468 4.14e-72 - - - K - - - Transcriptional regulator PadR-like family
HLJEPGAF_01469 2.09e-171 - - - - - - - -
HLJEPGAF_01470 1.57e-191 - - - - - - - -
HLJEPGAF_01471 3.37e-115 - - - - - - - -
HLJEPGAF_01472 1.01e-184 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
HLJEPGAF_01473 6.03e-218 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HLJEPGAF_01474 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
HLJEPGAF_01475 8.03e-151 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
HLJEPGAF_01476 0.0 etfA 1.3.1.108 - C ko:K03522,ko:K22432 - ko00000,ko01000,ko04147 Electron transfer flavoprotein FAD-binding domain
HLJEPGAF_01477 9.67e-98 - - - T - - - ECF transporter, substrate-specific component
HLJEPGAF_01479 5.29e-121 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
HLJEPGAF_01480 2.35e-243 dhaK2 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak1 domain
HLJEPGAF_01481 3.05e-236 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
HLJEPGAF_01482 7.88e-131 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
HLJEPGAF_01483 6.76e-75 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
HLJEPGAF_01484 2.32e-171 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HLJEPGAF_01485 2.65e-245 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
HLJEPGAF_01486 1.83e-231 yvdE - - K - - - helix_turn _helix lactose operon repressor
HLJEPGAF_01487 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
HLJEPGAF_01488 4.15e-191 yxeH - - S - - - hydrolase
HLJEPGAF_01489 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
HLJEPGAF_01490 1.14e-202 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
HLJEPGAF_01491 2.87e-101 ywiB - - S - - - Domain of unknown function (DUF1934)
HLJEPGAF_01492 2.96e-89 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HLJEPGAF_01493 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HLJEPGAF_01494 5.84e-312 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HLJEPGAF_01495 2.28e-290 sdaC - - E ko:K03837 - ko00000,ko02000 amino acid
HLJEPGAF_01496 7.51e-159 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
HLJEPGAF_01497 2.81e-202 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HLJEPGAF_01498 6.59e-170 - - - S - - - YheO-like PAS domain
HLJEPGAF_01499 4.01e-36 - - - - - - - -
HLJEPGAF_01500 2.08e-302 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HLJEPGAF_01501 1.26e-305 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HLJEPGAF_01502 1.91e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HLJEPGAF_01503 2.57e-274 - - - J - - - translation release factor activity
HLJEPGAF_01504 3.14e-164 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
HLJEPGAF_01505 5.35e-121 lemA - - S ko:K03744 - ko00000 LemA family
HLJEPGAF_01506 1.6e-194 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HLJEPGAF_01507 1.84e-189 - - - - - - - -
HLJEPGAF_01508 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HLJEPGAF_01509 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HLJEPGAF_01510 9.32e-81 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HLJEPGAF_01511 4.79e-273 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HLJEPGAF_01512 2.58e-85 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HLJEPGAF_01513 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
HLJEPGAF_01514 1.37e-248 - - - P ko:K02051 - ko00000,ko00002,ko02000 ABC transporter, substratebinding protein
HLJEPGAF_01515 3.03e-202 - - - U ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HLJEPGAF_01516 5.79e-171 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HLJEPGAF_01517 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HLJEPGAF_01518 7.48e-260 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HLJEPGAF_01519 8.87e-245 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HLJEPGAF_01520 2.29e-292 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HLJEPGAF_01521 2.36e-166 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
HLJEPGAF_01522 3.52e-273 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine
HLJEPGAF_01523 1.52e-240 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HLJEPGAF_01524 1.3e-110 queT - - S - - - QueT transporter
HLJEPGAF_01525 1.4e-147 - - - S - - - (CBS) domain
HLJEPGAF_01526 0.0 - - - S - - - Putative peptidoglycan binding domain
HLJEPGAF_01527 2.79e-226 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HLJEPGAF_01528 1.43e-129 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HLJEPGAF_01529 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HLJEPGAF_01530 0.0 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HLJEPGAF_01531 7.72e-57 yabO - - J - - - S4 domain protein
HLJEPGAF_01533 2.02e-83 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
HLJEPGAF_01534 1.07e-103 yabR - - J ko:K07571 - ko00000 RNA binding
HLJEPGAF_01535 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HLJEPGAF_01536 4.3e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HLJEPGAF_01537 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HLJEPGAF_01538 1.93e-209 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HLJEPGAF_01539 5.33e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HLJEPGAF_01540 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HLJEPGAF_01541 4.63e-24 - - - - - - - -
HLJEPGAF_01542 2.69e-23 - - - - - - - -
HLJEPGAF_01543 9.05e-22 - - - - - - - -
HLJEPGAF_01544 2.55e-217 inlJ - - M - - - MucBP domain
HLJEPGAF_01545 0.0 - - - D - - - nuclear chromosome segregation
HLJEPGAF_01546 1.27e-109 - - - K - - - MarR family
HLJEPGAF_01547 9.28e-58 - - - - - - - -
HLJEPGAF_01548 1.28e-51 - - - - - - - -
HLJEPGAF_01549 1.79e-289 - - - L - - - Belongs to the 'phage' integrase family
HLJEPGAF_01550 1.1e-06 - - - K ko:K07727 - ko00000,ko03000 transcriptional regulator
HLJEPGAF_01553 2.62e-40 - - - - - - - -
HLJEPGAF_01554 1.5e-187 - - - L - - - DNA replication protein
HLJEPGAF_01555 0.0 - - - S - - - Virulence-associated protein E
HLJEPGAF_01556 3.36e-96 - - - - - - - -
HLJEPGAF_01558 3.24e-62 - - - S - - - Head-tail joining protein
HLJEPGAF_01559 1.05e-88 - - - L ko:K07451 - ko00000,ko01000,ko02048 Phage-associated protein
HLJEPGAF_01560 1.9e-109 terS - - L - - - Phage terminase, small subunit
HLJEPGAF_01561 0.0 terL - - S - - - overlaps another CDS with the same product name
HLJEPGAF_01563 6.16e-260 - - - S - - - Phage portal protein
HLJEPGAF_01564 0.0 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
HLJEPGAF_01565 1.75e-48 - - - S - - - Phage gp6-like head-tail connector protein
HLJEPGAF_01566 1.02e-80 - - - - - - - -
HLJEPGAF_01568 1.98e-40 - - - - - - - -
HLJEPGAF_01570 9.38e-279 int3 - - L - - - Belongs to the 'phage' integrase family
HLJEPGAF_01574 4.23e-19 - - - S ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
HLJEPGAF_01576 2.69e-38 - - - S - - - TerB N-terminal domain
HLJEPGAF_01577 1.92e-97 - - - E - - - IrrE N-terminal-like domain
HLJEPGAF_01578 2.67e-80 - - - K - - - Helix-turn-helix domain
HLJEPGAF_01579 7.19e-51 - - - K - - - Helix-turn-helix
HLJEPGAF_01581 6.59e-72 - - - - - - - -
HLJEPGAF_01582 2.15e-110 - - - - - - - -
HLJEPGAF_01584 8e-70 - - - S - - - Bacteriophage Mu Gam like protein
HLJEPGAF_01585 6.45e-80 - - - - - - - -
HLJEPGAF_01586 7.28e-213 - - - L - - - DnaD domain protein
HLJEPGAF_01587 3.24e-67 - - - - - - - -
HLJEPGAF_01589 3.54e-18 - - - S - - - YopX protein
HLJEPGAF_01594 2.49e-97 - - - K - - - acetyltransferase
HLJEPGAF_01595 1.15e-40 - - - S - - - ASCH
HLJEPGAF_01596 7.56e-25 - - - - - - - -
HLJEPGAF_01599 3.13e-98 - - - L ko:K07474 - ko00000 Terminase small subunit
HLJEPGAF_01601 2.91e-316 - - - S ko:K06909 - ko00000 Phage terminase, large subunit
HLJEPGAF_01602 0.0 - - - S - - - Phage portal protein, SPP1 Gp6-like
HLJEPGAF_01603 5.76e-216 - - - S - - - Phage Mu protein F like protein
HLJEPGAF_01604 2.66e-110 - - - S - - - Domain of unknown function (DUF4355)
HLJEPGAF_01605 2.45e-247 gpG - - - - - - -
HLJEPGAF_01606 3.11e-75 - - - S - - - Phage gp6-like head-tail connector protein
HLJEPGAF_01607 5.46e-67 - - - - - - - -
HLJEPGAF_01608 9.66e-123 - - - - - - - -
HLJEPGAF_01609 5.59e-81 - - - - - - - -
HLJEPGAF_01610 2.09e-123 - - - - - - - -
HLJEPGAF_01611 5.37e-107 - - - S - - - Phage tail assembly chaperone protein, TAC
HLJEPGAF_01613 0.0 - - - D - - - domain protein
HLJEPGAF_01614 9.72e-173 - - - S - - - phage tail
HLJEPGAF_01615 0.0 - - - M - - - Prophage endopeptidase tail
HLJEPGAF_01616 2.64e-220 - - - E - - - GDSL-like Lipase/Acylhydrolase family
HLJEPGAF_01617 8.28e-127 - - - S - - - Domain of unknown function (DUF2479)
HLJEPGAF_01621 1.4e-108 - - - - - - - -
HLJEPGAF_01622 1.4e-27 - - - - - - - -
HLJEPGAF_01624 1.41e-214 - - - M - - - Glycosyl hydrolases family 25
HLJEPGAF_01625 1.97e-110 - - - S - - - Pfam:DUF3816
HLJEPGAF_01626 1.21e-306 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HLJEPGAF_01627 1.27e-143 - - - - - - - -
HLJEPGAF_01628 1.08e-229 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HLJEPGAF_01629 3.84e-185 - - - S - - - Peptidase_C39 like family
HLJEPGAF_01630 1.04e-120 - - - S - - - Protein of unknown function (DUF1694)
HLJEPGAF_01631 3.38e-150 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HLJEPGAF_01632 9.38e-189 - - - KT - - - helix_turn_helix, mercury resistance
HLJEPGAF_01633 3.41e-295 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HLJEPGAF_01634 1.86e-123 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
HLJEPGAF_01635 1.2e-240 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HLJEPGAF_01636 1.18e-155 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HLJEPGAF_01637 2.76e-117 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
HLJEPGAF_01638 5.72e-238 iunH3 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
HLJEPGAF_01639 3.55e-127 ywjB - - H - - - RibD C-terminal domain
HLJEPGAF_01640 9.35e-257 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HLJEPGAF_01641 7.1e-152 - - - S - - - Membrane
HLJEPGAF_01642 2.11e-199 mleP3 - - S ko:K07088 - ko00000 Membrane transport protein
HLJEPGAF_01643 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
HLJEPGAF_01644 4.32e-261 - - - EGP - - - Major Facilitator Superfamily
HLJEPGAF_01645 7.22e-163 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HLJEPGAF_01646 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
HLJEPGAF_01647 4.03e-104 - - - S - - - Domain of unknown function (DUF4811)
HLJEPGAF_01648 8.99e-133 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HLJEPGAF_01649 2.17e-222 - - - S - - - Conserved hypothetical protein 698
HLJEPGAF_01650 5.9e-194 rlrG - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
HLJEPGAF_01651 0.0 tagE5 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
HLJEPGAF_01652 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HLJEPGAF_01654 2.24e-78 - - - M - - - LysM domain
HLJEPGAF_01655 6.5e-119 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
HLJEPGAF_01656 1.65e-212 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HLJEPGAF_01657 3.91e-269 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HLJEPGAF_01658 6.27e-166 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HLJEPGAF_01659 4.72e-72 cmd 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
HLJEPGAF_01660 4.77e-100 yphH - - S - - - Cupin domain
HLJEPGAF_01661 5.19e-103 - - - K - - - transcriptional regulator, MerR family
HLJEPGAF_01662 4.87e-298 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HLJEPGAF_01663 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HLJEPGAF_01664 1.74e-156 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HLJEPGAF_01666 1.19e-150 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HLJEPGAF_01667 3.18e-141 thgA3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HLJEPGAF_01668 1.03e-150 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HLJEPGAF_01670 4.86e-111 - - - - - - - -
HLJEPGAF_01671 1.04e-110 yvbK - - K - - - GNAT family
HLJEPGAF_01672 9.76e-50 - - - - - - - -
HLJEPGAF_01673 2.81e-64 - - - - - - - -
HLJEPGAF_01674 7.44e-143 pgm8 - - G - - - Histidine phosphatase superfamily (branch 1)
HLJEPGAF_01675 6.09e-83 - - - S - - - Domain of unknown function (DUF4440)
HLJEPGAF_01676 1.51e-200 - - - K - - - LysR substrate binding domain
HLJEPGAF_01677 1.52e-135 - - - GM - - - NAD(P)H-binding
HLJEPGAF_01678 1.66e-247 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HLJEPGAF_01679 2.9e-194 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HLJEPGAF_01680 1.28e-45 - - - - - - - -
HLJEPGAF_01681 2.1e-99 - - - T - - - Belongs to the universal stress protein A family
HLJEPGAF_01682 2.09e-124 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
HLJEPGAF_01683 1.76e-162 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HLJEPGAF_01684 1.03e-40 - - - - - - - -
HLJEPGAF_01685 0.0 - - - U ko:K03451 - ko00000 Belongs to the BCCT transporter (TC 2.A.15) family
HLJEPGAF_01686 0.0 cadA - - P - - - P-type ATPase
HLJEPGAF_01688 9.45e-160 - - - S - - - YjbR
HLJEPGAF_01689 4.04e-37 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
HLJEPGAF_01690 3.23e-215 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
HLJEPGAF_01691 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HLJEPGAF_01692 1.44e-255 glmS2 - - M - - - SIS domain
HLJEPGAF_01693 2.07e-35 - - - S - - - Belongs to the LOG family
HLJEPGAF_01694 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HLJEPGAF_01695 3.98e-315 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HLJEPGAF_01696 5.85e-92 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HLJEPGAF_01697 5.38e-92 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HLJEPGAF_01698 4.75e-112 pgpA - - I - - - Phosphatidylglycerophosphatase A
HLJEPGAF_01699 1.07e-206 - - - GM - - - NmrA-like family
HLJEPGAF_01700 2.14e-86 - - - K ko:K22296 - ko00000,ko03000 Winged helix DNA-binding domain
HLJEPGAF_01701 9.97e-94 spxA - - P ko:K16509 - ko00000 ArsC family
HLJEPGAF_01702 3.46e-87 yeaO - - S - - - Protein of unknown function, DUF488
HLJEPGAF_01703 1.7e-70 - - - - - - - -
HLJEPGAF_01704 4.98e-275 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
HLJEPGAF_01705 2.11e-82 - - - - - - - -
HLJEPGAF_01706 1.36e-112 - - - - - - - -
HLJEPGAF_01707 4.58e-103 hsp3 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HLJEPGAF_01708 3.78e-73 - - - - - - - -
HLJEPGAF_01709 4.79e-21 - - - - - - - -
HLJEPGAF_01710 3.57e-150 - - - GM - - - NmrA-like family
HLJEPGAF_01711 2.52e-107 - - - S ko:K02348 - ko00000 GNAT family
HLJEPGAF_01712 9.43e-203 - - - EG - - - EamA-like transporter family
HLJEPGAF_01713 2.66e-155 - - - S - - - membrane
HLJEPGAF_01714 1.47e-144 - - - S - - - VIT family
HLJEPGAF_01715 4.38e-243 pva2 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
HLJEPGAF_01716 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HLJEPGAF_01717 8.01e-97 copR - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
HLJEPGAF_01718 4.26e-54 - - - - - - - -
HLJEPGAF_01719 3.43e-96 - - - S - - - COG NOG18757 non supervised orthologous group
HLJEPGAF_01720 8.8e-315 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
HLJEPGAF_01721 7.21e-35 - - - - - - - -
HLJEPGAF_01722 2.55e-65 - - - - - - - -
HLJEPGAF_01723 2.51e-84 - - - S - - - Protein of unknown function (DUF1398)
HLJEPGAF_01724 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
HLJEPGAF_01725 1.77e-282 mdtG - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
HLJEPGAF_01726 9.92e-230 ybcH - - D ko:K06889 - ko00000 Alpha beta
HLJEPGAF_01727 6.1e-101 - - - K - - - Domain of unknown function (DUF1836)
HLJEPGAF_01728 1.14e-110 - - - F - - - Nucleoside 2-deoxyribosyltransferase
HLJEPGAF_01729 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
HLJEPGAF_01730 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HLJEPGAF_01731 2.3e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
HLJEPGAF_01732 1.36e-209 yvgN - - C - - - Aldo keto reductase
HLJEPGAF_01733 2.57e-171 - - - S - - - Putative threonine/serine exporter
HLJEPGAF_01734 1.7e-101 - - - S - - - Threonine/Serine exporter, ThrE
HLJEPGAF_01735 1.5e-56 - - - S - - - Protein of unknown function (DUF1093)
HLJEPGAF_01736 2.69e-190 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HLJEPGAF_01737 5.94e-118 ymdB - - S - - - Macro domain protein
HLJEPGAF_01738 6.47e-124 - - - K ko:K22041 - ko00000,ko03000 transcriptional regulator
HLJEPGAF_01739 1.58e-66 - - - - - - - -
HLJEPGAF_01740 2.41e-212 - - - S - - - Protein of unknown function (DUF1002)
HLJEPGAF_01741 0.0 - - - - - - - -
HLJEPGAF_01742 2.08e-161 - - - S - - - Bacterial protein of unknown function (DUF916)
HLJEPGAF_01743 5.03e-43 - - - - - - - -
HLJEPGAF_01744 2.21e-178 - - - Q - - - Methyltransferase
HLJEPGAF_01745 2.84e-75 ybjQ - - S - - - Belongs to the UPF0145 family
HLJEPGAF_01746 1.66e-269 - - - EGP - - - Major facilitator Superfamily
HLJEPGAF_01747 3.58e-129 - - - K - - - Helix-turn-helix domain
HLJEPGAF_01748 1.52e-120 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HLJEPGAF_01749 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HLJEPGAF_01750 1.84e-67 - - - S - - - Lipopolysaccharide assembly protein A domain
HLJEPGAF_01751 7.09e-180 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HLJEPGAF_01752 8.34e-228 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HLJEPGAF_01753 6.62e-62 - - - - - - - -
HLJEPGAF_01754 1.55e-311 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HLJEPGAF_01755 3.02e-175 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
HLJEPGAF_01756 4.24e-218 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HLJEPGAF_01757 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
HLJEPGAF_01758 0.0 - 3.1.4.53 - S ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
HLJEPGAF_01759 0.0 cps4J - - S - - - MatE
HLJEPGAF_01760 4.82e-228 cps4I - - M - - - Glycosyltransferase like family 2
HLJEPGAF_01761 1.91e-297 - - - - - - - -
HLJEPGAF_01762 7.88e-48 cps4G - - M - - - Glycosyltransferase Family 4
HLJEPGAF_01763 1.82e-132 cps4G - - M - - - Glycosyltransferase Family 4
HLJEPGAF_01764 1.43e-223 cps4F - - M - - - Glycosyl transferases group 1
HLJEPGAF_01765 3.18e-162 tuaA - - M - - - Bacterial sugar transferase
HLJEPGAF_01766 8.71e-231 cps4D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
HLJEPGAF_01767 5.54e-189 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
HLJEPGAF_01768 2.02e-156 ywqD - - D - - - Capsular exopolysaccharide family
HLJEPGAF_01769 8.45e-162 epsB - - M - - - biosynthesis protein
HLJEPGAF_01770 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HLJEPGAF_01771 3.97e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HLJEPGAF_01772 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HLJEPGAF_01773 5.12e-31 - - - - - - - -
HLJEPGAF_01774 6.47e-95 - - - S - - - Iron-sulphur cluster biosynthesis
HLJEPGAF_01775 1.3e-65 - - - S - - - mazG nucleotide pyrophosphohydrolase
HLJEPGAF_01776 9.6e-143 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HLJEPGAF_01777 7.8e-300 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HLJEPGAF_01778 3.21e-288 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HLJEPGAF_01779 4.38e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HLJEPGAF_01780 9.34e-201 - - - S - - - Tetratricopeptide repeat
HLJEPGAF_01781 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HLJEPGAF_01782 1.29e-200 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HLJEPGAF_01783 1.8e-135 - - - EGP - - - Major Facilitator Superfamily
HLJEPGAF_01784 2.9e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HLJEPGAF_01785 1.18e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HLJEPGAF_01786 8.43e-240 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HLJEPGAF_01787 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HLJEPGAF_01788 7.1e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
HLJEPGAF_01789 2.1e-161 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
HLJEPGAF_01790 1.05e-251 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HLJEPGAF_01791 7.04e-108 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HLJEPGAF_01792 8.61e-132 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
HLJEPGAF_01793 1.91e-66 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
HLJEPGAF_01794 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HLJEPGAF_01795 1.45e-260 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HLJEPGAF_01796 0.0 - - - - - - - -
HLJEPGAF_01797 1.56e-262 icaA - - M - - - Glycosyl transferase family group 2
HLJEPGAF_01798 1.2e-233 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HLJEPGAF_01799 2.97e-244 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HLJEPGAF_01800 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HLJEPGAF_01801 1.55e-230 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HLJEPGAF_01802 5.55e-100 - - - K ko:K07726 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
HLJEPGAF_01803 6.61e-29 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
HLJEPGAF_01804 1.11e-33 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
HLJEPGAF_01805 3.38e-50 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
HLJEPGAF_01806 1.29e-235 - - - K - - - helix_turn_helix, arabinose operon control protein
HLJEPGAF_01807 5.91e-297 - - - P ko:K06610 - ko00000,ko02000 Major Facilitator Superfamily
HLJEPGAF_01808 0.0 ram2 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HLJEPGAF_01809 2.9e-293 - - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
HLJEPGAF_01810 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HLJEPGAF_01811 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HLJEPGAF_01812 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
HLJEPGAF_01813 1.95e-140 aqpZ - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HLJEPGAF_01814 3.7e-279 - - - S - - - associated with various cellular activities
HLJEPGAF_01815 9.34e-317 - - - S - - - Putative metallopeptidase domain
HLJEPGAF_01816 1.03e-65 - - - - - - - -
HLJEPGAF_01817 8.19e-134 yezE - - K ko:K16137 - ko00000,ko03000 Bacterial regulatory proteins, tetR family
HLJEPGAF_01818 7.83e-60 - - - - - - - -
HLJEPGAF_01819 4.23e-129 - - - S - - - WxL domain surface cell wall-binding
HLJEPGAF_01820 8.67e-160 - - - S - - - WxL domain surface cell wall-binding
HLJEPGAF_01821 1.83e-235 - - - S - - - Cell surface protein
HLJEPGAF_01822 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
HLJEPGAF_01823 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
HLJEPGAF_01824 1.06e-106 yoaA - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HLJEPGAF_01825 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
HLJEPGAF_01826 1.82e-152 rcfA - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
HLJEPGAF_01827 2.98e-44 copZ - - P - - - Heavy-metal-associated domain
HLJEPGAF_01828 4.27e-126 dpsB - - P - - - Belongs to the Dps family
HLJEPGAF_01829 1.01e-26 - - - - - - - -
HLJEPGAF_01830 4.82e-55 yrkD - - S - - - Metal-sensitive transcriptional repressor
HLJEPGAF_01831 5.73e-73 trxA3 - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Thioredoxin-like domain
HLJEPGAF_01832 9.44e-183 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HLJEPGAF_01833 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
HLJEPGAF_01834 8.06e-232 - - - E - - - GDSL-like Lipase/Acylhydrolase family
HLJEPGAF_01835 1.5e-165 - - - S - - - Gram-negative-bacterium-type cell wall biogenesis
HLJEPGAF_01836 4.16e-175 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HLJEPGAF_01837 4.84e-230 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
HLJEPGAF_01838 1.12e-134 - - - K - - - transcriptional regulator
HLJEPGAF_01840 9.39e-84 - - - - - - - -
HLJEPGAF_01842 5.77e-81 - - - - - - - -
HLJEPGAF_01843 6.18e-71 - - - - - - - -
HLJEPGAF_01844 1.88e-96 - - - M - - - PFAM NLP P60 protein
HLJEPGAF_01845 0.0 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
HLJEPGAF_01846 4.45e-38 - - - - - - - -
HLJEPGAF_01847 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
HLJEPGAF_01848 3.81e-150 - - - K - - - Bacterial regulatory proteins, tetR family
HLJEPGAF_01849 3.08e-113 - - - K - - - Winged helix DNA-binding domain
HLJEPGAF_01850 1.63e-176 yesN - - T ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HLJEPGAF_01851 3.17e-170 - - - S - - - WxL domain surface cell wall-binding
HLJEPGAF_01852 1.56e-71 - - - S - - - Bacterial protein of unknown function (DUF916)
HLJEPGAF_01853 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
HLJEPGAF_01854 2.92e-118 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
HLJEPGAF_01855 9.16e-190 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
HLJEPGAF_01856 5.09e-81 - - - V - - - Type I restriction modification DNA specificity domain
HLJEPGAF_01857 4.61e-222 - - - L - - - Belongs to the 'phage' integrase family
HLJEPGAF_01858 3.79e-57 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
HLJEPGAF_01859 4.85e-119 XK27_09665 - - G ko:K15640 - ko00000 Phosphoglycerate mutase family
HLJEPGAF_01860 0.0 - - - M - - - MucBP domain
HLJEPGAF_01861 5.1e-315 - - - M - - - MucBP domain
HLJEPGAF_01862 1.42e-08 - - - - - - - -
HLJEPGAF_01863 1.73e-113 - - - S - - - AAA domain
HLJEPGAF_01864 7.45e-180 - - - K - - - sequence-specific DNA binding
HLJEPGAF_01865 2.56e-60 - - - K - - - Helix-turn-helix domain
HLJEPGAF_01866 7.39e-54 - - - K - - - Helix-turn-helix domain
HLJEPGAF_01867 3.93e-220 - - - K - - - Transcriptional regulator
HLJEPGAF_01868 4.37e-120 - - - C - - - FMN_bind
HLJEPGAF_01869 5.68e-266 - - - C - - - FMN_bind
HLJEPGAF_01871 4.3e-106 - - - K - - - Transcriptional regulator
HLJEPGAF_01872 1.64e-149 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HLJEPGAF_01873 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
HLJEPGAF_01874 3.39e-255 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
HLJEPGAF_01875 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HLJEPGAF_01876 1.32e-290 - - - L - - - DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HLJEPGAF_01877 9.05e-55 - - - - - - - -
HLJEPGAF_01878 4.95e-44 - - - L - - - leucine-zipper of insertion element IS481
HLJEPGAF_01879 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HLJEPGAF_01880 9.95e-211 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HLJEPGAF_01881 5.06e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HLJEPGAF_01882 2.91e-179 - - - S - - - NADPH-dependent FMN reductase
HLJEPGAF_01883 2.26e-243 - - - - - - - -
HLJEPGAF_01884 1.89e-277 yibE - - S - - - overlaps another CDS with the same product name
HLJEPGAF_01885 4.18e-163 yibF - - S - - - overlaps another CDS with the same product name
HLJEPGAF_01886 7.84e-117 - - - K - - - FR47-like protein
HLJEPGAF_01887 1.24e-155 gpm5 - - G - - - Phosphoglycerate mutase family
HLJEPGAF_01888 3.33e-64 - - - - - - - -
HLJEPGAF_01889 4.24e-246 - - - I - - - alpha/beta hydrolase fold
HLJEPGAF_01890 0.0 xylP2 - - G - - - symporter
HLJEPGAF_01891 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HLJEPGAF_01892 9.85e-281 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
HLJEPGAF_01893 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HLJEPGAF_01894 3.43e-66 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
HLJEPGAF_01895 2.03e-155 azlC - - E - - - branched-chain amino acid
HLJEPGAF_01896 1.75e-47 - - - K - - - MerR HTH family regulatory protein
HLJEPGAF_01897 1.46e-170 - - - - - - - -
HLJEPGAF_01898 2.72e-152 - - - S - - - Domain of unknown function (DUF4811)
HLJEPGAF_01899 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
HLJEPGAF_01900 7.79e-112 - - - K - - - MerR HTH family regulatory protein
HLJEPGAF_01901 1.36e-77 - - - - - - - -
HLJEPGAF_01902 2.94e-155 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
HLJEPGAF_01903 1.78e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HLJEPGAF_01904 4.6e-169 - - - S - - - Putative threonine/serine exporter
HLJEPGAF_01905 7.76e-100 - - - S - - - Threonine/Serine exporter, ThrE
HLJEPGAF_01906 4.1e-223 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
HLJEPGAF_01907 3.22e-82 - - - S - - - Protein of unknown function (DUF3397)
HLJEPGAF_01908 7.24e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HLJEPGAF_01909 1.74e-224 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HLJEPGAF_01910 7.01e-76 ftsL - - D - - - Cell division protein FtsL
HLJEPGAF_01911 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HLJEPGAF_01912 2.81e-231 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HLJEPGAF_01913 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HLJEPGAF_01914 2.04e-252 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HLJEPGAF_01915 2.34e-208 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HLJEPGAF_01916 3.55e-312 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HLJEPGAF_01917 9.39e-295 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HLJEPGAF_01918 1.56e-93 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HLJEPGAF_01919 6.45e-49 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
HLJEPGAF_01920 2.06e-187 ylmH - - S - - - S4 domain protein
HLJEPGAF_01921 6.52e-124 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
HLJEPGAF_01922 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HLJEPGAF_01923 3.46e-242 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HLJEPGAF_01924 3.51e-125 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
HLJEPGAF_01925 7.74e-47 - - - - - - - -
HLJEPGAF_01926 5.85e-158 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HLJEPGAF_01927 8.09e-275 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HLJEPGAF_01928 4.94e-75 XK27_04120 - - S - - - Putative amino acid metabolism
HLJEPGAF_01929 1.53e-284 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HLJEPGAF_01930 9.64e-307 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
HLJEPGAF_01931 4.64e-150 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
HLJEPGAF_01932 4.17e-153 - - - N - - - WxL domain surface cell wall-binding
HLJEPGAF_01933 2.02e-247 - - - S - - - Bacterial protein of unknown function (DUF916)
HLJEPGAF_01934 0.0 - - - N - - - domain, Protein
HLJEPGAF_01935 2.41e-157 pgm6 - - G - - - phosphoglycerate mutase
HLJEPGAF_01936 1.02e-155 - - - S - - - repeat protein
HLJEPGAF_01937 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HLJEPGAF_01938 5.35e-220 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HLJEPGAF_01939 2.62e-168 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
HLJEPGAF_01940 2.16e-39 - - - - - - - -
HLJEPGAF_01941 3.45e-240 ytlR - - I - - - Diacylglycerol kinase catalytic domain
HLJEPGAF_01942 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HLJEPGAF_01943 4.86e-45 ykzG - - S - - - Belongs to the UPF0356 family
HLJEPGAF_01944 6.45e-111 - - - - - - - -
HLJEPGAF_01945 3.95e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HLJEPGAF_01946 1.21e-268 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
HLJEPGAF_01947 8.65e-228 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
HLJEPGAF_01948 2.36e-285 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HLJEPGAF_01949 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
HLJEPGAF_01950 2.15e-209 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 L-malate dehydrogenase activity
HLJEPGAF_01951 2.64e-62 yktA - - S - - - Belongs to the UPF0223 family
HLJEPGAF_01952 7.1e-177 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
HLJEPGAF_01953 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HLJEPGAF_01954 4.84e-227 - - - - - - - -
HLJEPGAF_01955 4.08e-101 - - - K - - - MerR family regulatory protein
HLJEPGAF_01956 7.54e-200 - - - GM - - - NmrA-like family
HLJEPGAF_01957 0.0 pts28ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HLJEPGAF_01958 1.25e-164 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
HLJEPGAF_01960 2.95e-100 - - - S - - - NADPH-dependent FMN reductase
HLJEPGAF_01961 8.44e-304 - - - S - - - module of peptide synthetase
HLJEPGAF_01962 1.16e-135 - - - - - - - -
HLJEPGAF_01963 1.55e-114 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
HLJEPGAF_01964 1.28e-77 - - - S - - - Enterocin A Immunity
HLJEPGAF_01965 6.46e-49 - - - S - - - Phospholipase_D-nuclease N-terminal
HLJEPGAF_01966 7.47e-77 - 3.1.4.17, 3.1.4.53 - S ko:K01120,ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
HLJEPGAF_01967 1.33e-100 - 3.1.4.17, 3.1.4.53 - S ko:K01120,ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
HLJEPGAF_01968 2.8e-135 - - - J - - - Acetyltransferase (GNAT) domain
HLJEPGAF_01969 4.14e-84 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
HLJEPGAF_01970 2.88e-164 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
HLJEPGAF_01971 1.56e-185 WQ51_01275 - - S - - - EDD domain protein, DegV family
HLJEPGAF_01972 1.03e-34 - - - - - - - -
HLJEPGAF_01973 7.02e-151 yugP - - S ko:K06973 - ko00000 Putative neutral zinc metallopeptidase
HLJEPGAF_01974 0.0 - 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 - Q ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 ko00000,ko00001,ko01000 Flavin containing amine oxidoreductase
HLJEPGAF_01975 2.85e-210 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Squalene/phytoene synthase
HLJEPGAF_01976 9.07e-233 - - - D ko:K06889 - ko00000 Alpha beta
HLJEPGAF_01977 1.49e-253 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HLJEPGAF_01978 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
HLJEPGAF_01979 2.05e-72 - - - S - - - Enterocin A Immunity
HLJEPGAF_01980 3.66e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HLJEPGAF_01981 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HLJEPGAF_01982 4.17e-235 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HLJEPGAF_01983 1.02e-187 ptp2 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HLJEPGAF_01984 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HLJEPGAF_01986 4.62e-107 - - - - - - - -
HLJEPGAF_01987 0.0 yhdG - - E ko:K03294 - ko00000 C-terminus of AA_permease
HLJEPGAF_01989 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
HLJEPGAF_01990 1.07e-211 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HLJEPGAF_01991 3.1e-228 ydbI - - K - - - AI-2E family transporter
HLJEPGAF_01992 1.38e-275 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HLJEPGAF_01993 1.63e-77 - - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
HLJEPGAF_01994 1.97e-60 qacH - - U ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
HLJEPGAF_01995 2.94e-149 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
HLJEPGAF_01996 7.27e-73 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
HLJEPGAF_01997 1.3e-207 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
HLJEPGAF_01998 8.03e-28 - - - - - - - -
HLJEPGAF_01999 3.91e-124 tag2 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
HLJEPGAF_02000 5.59e-271 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
HLJEPGAF_02001 2.01e-134 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
HLJEPGAF_02002 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HLJEPGAF_02003 1.8e-134 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
HLJEPGAF_02004 1.59e-121 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HLJEPGAF_02005 9.61e-84 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HLJEPGAF_02006 4.26e-109 cvpA - - S - - - Colicin V production protein
HLJEPGAF_02007 5.61e-216 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HLJEPGAF_02008 8.83e-317 - - - EGP - - - Major Facilitator
HLJEPGAF_02010 4.54e-54 - - - - - - - -
HLJEPGAF_02011 2.81e-167 zmp3 - - O - - - Zinc-dependent metalloprotease
HLJEPGAF_02012 2.88e-106 gtcA3 - - S - - - GtrA-like protein
HLJEPGAF_02013 3.35e-157 - - - K - - - Helix-turn-helix XRE-family like proteins
HLJEPGAF_02014 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HLJEPGAF_02015 1.18e-94 usp2 - - T - - - Belongs to the universal stress protein A family
HLJEPGAF_02016 7.03e-62 - - - - - - - -
HLJEPGAF_02017 1.81e-150 - - - S - - - SNARE associated Golgi protein
HLJEPGAF_02018 8.58e-65 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
HLJEPGAF_02019 7.89e-124 - - - P - - - Cadmium resistance transporter
HLJEPGAF_02020 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HLJEPGAF_02021 3.93e-38 - - - P - - - Concanavalin A-like lectin/glucanases superfamily
HLJEPGAF_02023 2.03e-84 - - - - - - - -
HLJEPGAF_02024 1.58e-204 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
HLJEPGAF_02025 1.21e-73 - - - - - - - -
HLJEPGAF_02026 1.24e-194 - - - K - - - Helix-turn-helix domain
HLJEPGAF_02027 3.91e-100 pts23A - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HLJEPGAF_02028 7.47e-70 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HLJEPGAF_02029 0.0 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLJEPGAF_02030 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HLJEPGAF_02031 4.32e-235 - - - GM - - - Male sterility protein
HLJEPGAF_02032 2.1e-99 - - - K - - - helix_turn_helix, mercury resistance
HLJEPGAF_02033 4.61e-101 - - - M - - - LysM domain
HLJEPGAF_02034 7.94e-126 - - - M - - - Lysin motif
HLJEPGAF_02035 5.71e-138 - - - S - - - SdpI/YhfL protein family
HLJEPGAF_02036 1.58e-72 nudA - - S - - - ASCH
HLJEPGAF_02037 5.76e-212 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HLJEPGAF_02038 3.57e-120 - - - - - - - -
HLJEPGAF_02039 1.92e-155 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Methyladenine glycosylase
HLJEPGAF_02040 3.55e-281 - - - T - - - diguanylate cyclase
HLJEPGAF_02041 7.43e-97 - - - S - - - Psort location Cytoplasmic, score
HLJEPGAF_02042 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
HLJEPGAF_02043 2.31e-277 - - - - - - - -
HLJEPGAF_02044 0.0 - - - V ko:K06147,ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HLJEPGAF_02045 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HLJEPGAF_02047 3.23e-290 amd - - E - - - Peptidase family M20/M25/M40
HLJEPGAF_02048 2.96e-209 yhxD - - IQ - - - KR domain
HLJEPGAF_02050 1.97e-92 - - - - - - - -
HLJEPGAF_02051 1.43e-184 - - - K - - - Helix-turn-helix XRE-family like proteins
HLJEPGAF_02052 0.0 - - - E - - - Amino Acid
HLJEPGAF_02053 4.8e-86 lysM - - M - - - LysM domain
HLJEPGAF_02054 4.2e-286 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
HLJEPGAF_02055 6.8e-272 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
HLJEPGAF_02056 0.0 copA 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HLJEPGAF_02057 1.23e-57 - - - S - - - Cupredoxin-like domain
HLJEPGAF_02058 1.36e-84 - - - S - - - Cupredoxin-like domain
HLJEPGAF_02059 2.69e-316 dinF - - V - - - MatE
HLJEPGAF_02060 1.79e-42 - - - - - - - -
HLJEPGAF_02062 8.2e-102 yybD - - S ko:K02348 - ko00000 Acetyltransferase (GNAT) domain
HLJEPGAF_02063 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HLJEPGAF_02064 4.64e-106 - - - - - - - -
HLJEPGAF_02065 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
HLJEPGAF_02066 1.04e-136 - - - - - - - -
HLJEPGAF_02067 0.0 celR - - K - - - PRD domain
HLJEPGAF_02068 1.34e-104 - - - S - - - Domain of unknown function (DUF3284)
HLJEPGAF_02069 2.37e-68 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
HLJEPGAF_02070 4.9e-64 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HLJEPGAF_02071 1.71e-277 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLJEPGAF_02072 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HLJEPGAF_02073 3.5e-271 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
HLJEPGAF_02074 2.34e-146 yciB - - M - - - ErfK YbiS YcfS YnhG
HLJEPGAF_02075 1.65e-46 dltC2 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLJEPGAF_02076 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 Alanine-glyoxylate amino-transferase
HLJEPGAF_02077 8.08e-133 argO - - S ko:K06895 - ko00000,ko02000 LysE type translocator
HLJEPGAF_02078 5.58e-271 arcT - - E - - - Aminotransferase
HLJEPGAF_02079 2.07e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HLJEPGAF_02080 2.43e-18 - - - - - - - -
HLJEPGAF_02081 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HLJEPGAF_02082 9.94e-71 yheA - - S - - - Belongs to the UPF0342 family
HLJEPGAF_02083 4.47e-296 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
HLJEPGAF_02084 0.0 yhaN - - L - - - AAA domain
HLJEPGAF_02085 1.03e-240 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
HLJEPGAF_02086 1.05e-272 - - - - - - - -
HLJEPGAF_02087 2.41e-233 - - - M - - - Peptidase family S41
HLJEPGAF_02088 1.09e-225 - - - K - - - LysR substrate binding domain
HLJEPGAF_02089 9.9e-144 - - - S - - - NADPH-dependent FMN reductase
HLJEPGAF_02090 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HLJEPGAF_02091 4.43e-129 - - - - - - - -
HLJEPGAF_02092 1.17e-100 - 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside 2-deoxyribosyltransferase
HLJEPGAF_02093 1.15e-235 ykoT - - M - - - Glycosyl transferase family 2
HLJEPGAF_02094 7.78e-20 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HLJEPGAF_02095 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HLJEPGAF_02096 4.29e-26 - - - S - - - NUDIX domain
HLJEPGAF_02097 0.0 - - - S - - - membrane
HLJEPGAF_02098 4.26e-218 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HLJEPGAF_02099 2.61e-95 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
HLJEPGAF_02100 2.08e-284 ribA 3.5.4.25, 4.1.99.12 - H ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HLJEPGAF_02101 1.23e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HLJEPGAF_02102 5.21e-137 - - - S ko:K09962 - ko00000 Nucleotidyltransferase
HLJEPGAF_02103 1.96e-137 - - - - - - - -
HLJEPGAF_02104 3.3e-151 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
HLJEPGAF_02105 1.08e-95 - - - K - - - Bacterial regulatory proteins, tetR family
HLJEPGAF_02106 2e-98 yugI - - J ko:K07570,ko:K07571 - ko00000 general stress protein
HLJEPGAF_02107 5.16e-141 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HLJEPGAF_02108 8.38e-152 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
HLJEPGAF_02109 2.71e-150 - - - S - - - Protein of unknown function (DUF1461)
HLJEPGAF_02110 7.18e-189 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HLJEPGAF_02111 1.96e-116 yutD - - S - - - Protein of unknown function (DUF1027)
HLJEPGAF_02112 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HLJEPGAF_02113 5.77e-151 - - - S - - - Calcineurin-like phosphoesterase
HLJEPGAF_02114 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HLJEPGAF_02115 4.7e-282 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HLJEPGAF_02116 3.68e-235 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
HLJEPGAF_02118 6.46e-113 - - - S - - - Prokaryotic N-terminal methylation motif
HLJEPGAF_02119 3.03e-27 - - - - ko:K02671 - ko00000,ko02035,ko02044 -
HLJEPGAF_02120 1.5e-108 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
HLJEPGAF_02121 1.97e-72 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
HLJEPGAF_02122 6.2e-242 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
HLJEPGAF_02123 2.57e-224 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
HLJEPGAF_02124 2.06e-205 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HLJEPGAF_02125 2.21e-168 yebC - - K - - - Transcriptional regulatory protein
HLJEPGAF_02126 2.44e-65 - - - S ko:K09004 - ko00000 DsrE/DsrF-like family
HLJEPGAF_02127 3.21e-210 - - - G - - - Xylose isomerase domain protein TIM barrel
HLJEPGAF_02128 5.44e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
HLJEPGAF_02129 7.36e-274 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HLJEPGAF_02130 9.86e-82 - - - K - - - helix_turn_helix, mercury resistance
HLJEPGAF_02131 1.6e-96 - - - - - - - -
HLJEPGAF_02132 1.88e-75 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HLJEPGAF_02133 2.31e-202 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
HLJEPGAF_02134 6.72e-289 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HLJEPGAF_02135 2.29e-112 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HLJEPGAF_02136 7.94e-114 ykuL - - S - - - (CBS) domain
HLJEPGAF_02137 4.03e-125 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
HLJEPGAF_02138 8.49e-144 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HLJEPGAF_02139 5.06e-194 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HLJEPGAF_02140 1.45e-161 yslB - - S - - - Protein of unknown function (DUF2507)
HLJEPGAF_02141 3e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HLJEPGAF_02142 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HLJEPGAF_02143 1.06e-49 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HLJEPGAF_02144 1.31e-63 yrzB - - S - - - Belongs to the UPF0473 family
HLJEPGAF_02145 5.39e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HLJEPGAF_02146 5e-57 yrzL - - S - - - Belongs to the UPF0297 family
HLJEPGAF_02147 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HLJEPGAF_02148 2.79e-316 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HLJEPGAF_02149 8.32e-227 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
HLJEPGAF_02150 2.48e-276 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HLJEPGAF_02151 1.32e-63 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HLJEPGAF_02152 9.91e-289 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HLJEPGAF_02153 5.87e-256 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HLJEPGAF_02154 2.62e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HLJEPGAF_02155 2.83e-138 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HLJEPGAF_02156 4.02e-114 - - - - - - - -
HLJEPGAF_02157 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
HLJEPGAF_02158 1.3e-91 - - - - - - - -
HLJEPGAF_02159 0.0 - - - L ko:K07487 - ko00000 Transposase
HLJEPGAF_02160 3.12e-201 - - - M - - - Glycosyl hydrolases family 25
HLJEPGAF_02161 2.91e-29 - - - - - - - -
HLJEPGAF_02162 1.93e-102 - - - - - - - -
HLJEPGAF_02166 4.43e-168 - - - S - - - Phage minor structural protein
HLJEPGAF_02167 0.0 - - - S - - - Phage tail protein
HLJEPGAF_02168 0.0 - - - D - - - domain protein
HLJEPGAF_02169 6.36e-34 - - - - - - - -
HLJEPGAF_02170 1.35e-75 - - - S - - - Phage tail assembly chaperone proteins, TAC
HLJEPGAF_02171 2.16e-131 - - - S - - - Phage tail tube protein
HLJEPGAF_02172 7.47e-74 - - - S - - - Protein of unknown function (DUF806)
HLJEPGAF_02173 2.25e-86 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
HLJEPGAF_02174 3.45e-76 - - - S - - - Phage head-tail joining protein
HLJEPGAF_02175 9.36e-65 - - - S - - - Phage gp6-like head-tail connector protein
HLJEPGAF_02176 1.03e-254 - - - S - - - Phage capsid family
HLJEPGAF_02177 5.99e-164 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
HLJEPGAF_02178 6.97e-284 - - - S - - - Phage portal protein
HLJEPGAF_02179 6.68e-35 - - - S - - - Protein of unknown function (DUF1056)
HLJEPGAF_02180 0.0 - - - S - - - Phage Terminase
HLJEPGAF_02181 6.68e-103 - - - L - - - Phage terminase, small subunit
HLJEPGAF_02183 7.81e-113 - - - L - - - HNH nucleases
HLJEPGAF_02184 1.13e-84 - - - S - - - Transcriptional regulator, RinA family
HLJEPGAF_02185 2.2e-23 - - - - - - - -
HLJEPGAF_02186 5.27e-72 - - - - - - - -
HLJEPGAF_02187 1.28e-09 - - - S - - - YopX protein
HLJEPGAF_02189 8.89e-118 - - - L - - - C-5 cytosine-specific DNA methylase
HLJEPGAF_02191 2.95e-06 - - - - - - - -
HLJEPGAF_02192 1.01e-20 - - - L - - - Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HLJEPGAF_02194 2.84e-169 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
HLJEPGAF_02195 2.93e-167 - - - S - - - Putative HNHc nuclease
HLJEPGAF_02196 3.13e-127 - - - S - - - Protein of unknown function (DUF669)
HLJEPGAF_02197 3.98e-151 - - - S - - - AAA domain
HLJEPGAF_02198 4.24e-188 - - - S - - - Protein of unknown function (DUF1351)
HLJEPGAF_02200 2e-25 - - - - - - - -
HLJEPGAF_02207 7.34e-80 - - - S - - - DNA binding
HLJEPGAF_02210 1.56e-27 - - - - - - - -
HLJEPGAF_02211 2.59e-99 - - - K - - - Peptidase S24-like
HLJEPGAF_02218 6.15e-75 int3 - - L - - - Belongs to the 'phage' integrase family
HLJEPGAF_02219 3.73e-131 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
HLJEPGAF_02220 2.33e-283 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
HLJEPGAF_02221 1.07e-131 - - - M - - - Protein of unknown function (DUF3737)
HLJEPGAF_02222 1.8e-249 - - - C - - - Aldo/keto reductase family
HLJEPGAF_02224 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HLJEPGAF_02225 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HLJEPGAF_02226 6.27e-316 - - - EGP - - - Major Facilitator
HLJEPGAF_02231 2.06e-313 yhgE - - V ko:K01421 - ko00000 domain protein
HLJEPGAF_02232 1.23e-123 - - - K - - - Transcriptional regulator (TetR family)
HLJEPGAF_02233 6.88e-71 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HLJEPGAF_02234 4.36e-197 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
HLJEPGAF_02235 1.39e-134 yokL3 - - J - - - Acetyltransferase (GNAT) domain
HLJEPGAF_02236 8.76e-126 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HLJEPGAF_02237 2.09e-287 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HLJEPGAF_02238 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
HLJEPGAF_02239 5.69e-191 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HLJEPGAF_02240 0.0 - - - S - - - Predicted membrane protein (DUF2207)
HLJEPGAF_02241 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC
HLJEPGAF_02242 1.35e-264 - - - EGP - - - Major facilitator Superfamily
HLJEPGAF_02243 1.54e-219 ropB - - K - - - Helix-turn-helix XRE-family like proteins
HLJEPGAF_02244 1.76e-298 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
HLJEPGAF_02245 0.0 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
HLJEPGAF_02246 9.55e-205 - - - I - - - alpha/beta hydrolase fold
HLJEPGAF_02247 1.01e-167 treR - - K ko:K03486 - ko00000,ko03000 UTRA
HLJEPGAF_02248 0.0 - - - - - - - -
HLJEPGAF_02249 2e-52 - - - S - - - Cytochrome B5
HLJEPGAF_02250 8.68e-118 pts21A - - G ko:K02755 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HLJEPGAF_02251 6.48e-135 - - - T - - - Diguanylate cyclase, GGDEF domain
HLJEPGAF_02252 6.39e-169 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
HLJEPGAF_02253 8.05e-166 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HLJEPGAF_02254 1.9e-230 - - - S ko:K06889 - ko00000 Prolyl oligopeptidase family
HLJEPGAF_02255 2.26e-209 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HLJEPGAF_02256 6.87e-50 veg - - S - - - Biofilm formation stimulator VEG
HLJEPGAF_02257 1.19e-201 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HLJEPGAF_02258 1.6e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HLJEPGAF_02259 1.63e-187 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
HLJEPGAF_02261 2.53e-106 mutR - - K ko:K20373,ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
HLJEPGAF_02262 1.81e-273 - - - EGP ko:K02030 - ko00000,ko00002,ko02000 Drug resistance transporter Bcr CflA subfamily
HLJEPGAF_02263 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HLJEPGAF_02264 4.64e-92 - - - F - - - DNA mismatch repair protein MutT
HLJEPGAF_02265 1.12e-205 yunF - - F - - - Protein of unknown function DUF72
HLJEPGAF_02266 3.56e-170 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
HLJEPGAF_02267 7.71e-228 - - - - - - - -
HLJEPGAF_02268 1.37e-290 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
HLJEPGAF_02269 1.36e-214 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HLJEPGAF_02270 4.87e-243 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HLJEPGAF_02271 1.6e-77 chpA - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
HLJEPGAF_02272 5.9e-46 - - - - - - - -
HLJEPGAF_02273 1.69e-97 - - - S - - - Domain of unknown function (DUF3284)
HLJEPGAF_02274 9.68e-34 - - - - - - - -
HLJEPGAF_02275 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLJEPGAF_02276 2.69e-166 - - - K - - - UbiC transcription regulator-associated domain protein
HLJEPGAF_02277 2.35e-243 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HLJEPGAF_02278 1.38e-179 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
HLJEPGAF_02279 0.0 - - - L - - - DNA helicase
HLJEPGAF_02280 4.23e-64 axe - - K ko:K21498 - ko00000,ko02048 Helix-turn-helix XRE-family like proteins
HLJEPGAF_02281 3.74e-144 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HLJEPGAF_02282 4.56e-144 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
HLJEPGAF_02283 8.02e-152 plnU - - S ko:K07052 - ko00000 CAAX protease self-immunity
HLJEPGAF_02284 2.6e-140 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HLJEPGAF_02285 1.17e-306 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
HLJEPGAF_02286 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HLJEPGAF_02287 2.59e-19 - - - - - - - -
HLJEPGAF_02288 1.93e-31 plnF - - - - - - -
HLJEPGAF_02289 8.15e-167 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HLJEPGAF_02290 1.17e-60 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
HLJEPGAF_02291 6.27e-216 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
HLJEPGAF_02292 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HLJEPGAF_02293 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HLJEPGAF_02294 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
HLJEPGAF_02295 3.97e-229 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
HLJEPGAF_02296 0.0 - 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HLJEPGAF_02297 4.71e-210 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
HLJEPGAF_02298 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HLJEPGAF_02299 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HLJEPGAF_02300 1.63e-163 mleR - - K - - - LysR substrate binding domain
HLJEPGAF_02301 5.44e-35 mleR - - K - - - LysR substrate binding domain
HLJEPGAF_02302 0.0 - - - M - - - domain protein
HLJEPGAF_02304 1.03e-201 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
HLJEPGAF_02305 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HLJEPGAF_02306 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HLJEPGAF_02307 2.65e-102 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HLJEPGAF_02308 1.45e-278 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLJEPGAF_02309 1.24e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HLJEPGAF_02310 6.7e-148 pgm1 - - G - - - phosphoglycerate mutase
HLJEPGAF_02311 3.38e-227 yghZ - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
HLJEPGAF_02312 6.33e-46 - - - - - - - -
HLJEPGAF_02313 1.15e-79 - - - S - - - Domain of unknown function (DU1801)
HLJEPGAF_02314 4.37e-208 fbpA - - K - - - Domain of unknown function (DUF814)
HLJEPGAF_02315 1.29e-278 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HLJEPGAF_02316 3.81e-18 - - - - - - - -
HLJEPGAF_02317 3.18e-77 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLJEPGAF_02318 5.66e-74 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLJEPGAF_02319 2.2e-280 - - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
HLJEPGAF_02320 9.2e-215 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HLJEPGAF_02321 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HLJEPGAF_02322 8.69e-230 citR - - K - - - sugar-binding domain protein
HLJEPGAF_02323 1.11e-263 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
HLJEPGAF_02324 3.07e-241 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HLJEPGAF_02325 1.23e-58 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
HLJEPGAF_02326 1.51e-206 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
HLJEPGAF_02327 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
HLJEPGAF_02328 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HLJEPGAF_02329 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HLJEPGAF_02330 2.32e-121 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HLJEPGAF_02331 4.54e-207 mleR2 - - K - - - LysR family transcriptional regulator
HLJEPGAF_02332 1.53e-213 mleR - - K - - - LysR family
HLJEPGAF_02333 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
HLJEPGAF_02334 2.6e-212 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
HLJEPGAF_02335 0.0 - - - E ko:K03294 - ko00000 Amino Acid
HLJEPGAF_02336 4.37e-128 - - - S - - - ECF transporter, substrate-specific component
HLJEPGAF_02337 6.07e-33 - - - - - - - -
HLJEPGAF_02338 0.0 - - - S ko:K06889 - ko00000 Alpha beta
HLJEPGAF_02339 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
HLJEPGAF_02340 7.76e-234 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
HLJEPGAF_02341 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HLJEPGAF_02342 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HLJEPGAF_02343 1.89e-208 - - - S - - - L,D-transpeptidase catalytic domain
HLJEPGAF_02344 2.53e-233 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HLJEPGAF_02345 4.92e-212 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
HLJEPGAF_02346 1.5e-104 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HLJEPGAF_02347 5.55e-22 - - - G ko:K11203 - ko00000,ko00002,ko02000 PTS system, fructose subfamily
HLJEPGAF_02348 2.52e-35 - 2.7.1.202 - G ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HLJEPGAF_02349 9.49e-155 fptC - - U ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 Phosphotransferase system, EIIC
HLJEPGAF_02350 0.0 mngB 3.2.1.170 GH38 G ko:K15524 - ko00000,ko01000 Glycosyl hydrolases family 38 N-terminal domain
HLJEPGAF_02351 2.24e-116 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
HLJEPGAF_02352 3.54e-190 - - - S - - - haloacid dehalogenase-like hydrolase
HLJEPGAF_02353 2.69e-194 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
HLJEPGAF_02354 6.26e-101 - - - - - - - -
HLJEPGAF_02355 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HLJEPGAF_02356 2.93e-151 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HLJEPGAF_02357 2.44e-165 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
HLJEPGAF_02358 3.73e-263 - - - S - - - DUF218 domain
HLJEPGAF_02359 1.06e-232 purR2 - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
HLJEPGAF_02360 0.0 malL 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HLJEPGAF_02361 0.0 pts26BCA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HLJEPGAF_02362 1.6e-200 - - - S - - - Putative adhesin
HLJEPGAF_02363 1.73e-132 - - - S - - - Protein of unknown function (DUF1700)
HLJEPGAF_02364 2.86e-68 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator
HLJEPGAF_02365 1.07e-127 - - - KT - - - response to antibiotic
HLJEPGAF_02366 1.26e-161 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HLJEPGAF_02367 3.02e-176 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HLJEPGAF_02368 2.11e-158 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HLJEPGAF_02369 2.13e-167 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HLJEPGAF_02370 2.07e-302 - - - EK - - - Aminotransferase, class I
HLJEPGAF_02371 3.36e-216 - - - K - - - LysR substrate binding domain
HLJEPGAF_02372 3.66e-189 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HLJEPGAF_02373 2.89e-312 yfhO - - S - - - Bacterial membrane protein YfhO
HLJEPGAF_02374 1.15e-43 - - - - - - - -
HLJEPGAF_02376 1.04e-269 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
HLJEPGAF_02377 4.54e-191 livH - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
HLJEPGAF_02378 2.29e-193 livM - - E ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
HLJEPGAF_02379 5.21e-180 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
HLJEPGAF_02380 2.78e-158 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
HLJEPGAF_02381 3.13e-42 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
HLJEPGAF_02382 5.06e-82 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
HLJEPGAF_02383 1.27e-137 - - - S - - - WxL domain surface cell wall-binding
HLJEPGAF_02384 5.52e-242 - - - S - - - Cell surface protein
HLJEPGAF_02385 4.71e-81 - - - - - - - -
HLJEPGAF_02386 0.0 - - - - - - - -
HLJEPGAF_02387 6.97e-216 XK27_00670 - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HLJEPGAF_02388 5.82e-198 WQ51_06230 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HLJEPGAF_02389 4.21e-150 - - - S ko:K05833 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HLJEPGAF_02390 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HLJEPGAF_02391 8.08e-154 ydgI3 - - C - - - Nitroreductase family
HLJEPGAF_02392 2.21e-154 yceE - - S - - - haloacid dehalogenase-like hydrolase
HLJEPGAF_02393 5.85e-204 ccpB - - K - - - lacI family
HLJEPGAF_02394 7.39e-121 - - - K - - - Transcriptional regulator, MarR family
HLJEPGAF_02395 9.21e-234 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
HLJEPGAF_02396 1.02e-164 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
HLJEPGAF_02397 9.86e-117 - - - - - - - -
HLJEPGAF_02398 0.0 ybfG - - M - - - peptidoglycan-binding domain-containing protein
HLJEPGAF_02399 3.06e-206 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HLJEPGAF_02400 5.07e-62 - - - K - - - HxlR-like helix-turn-helix
HLJEPGAF_02401 5.93e-144 - - - K - - - Transcriptional regulator C-terminal region
HLJEPGAF_02402 3.39e-225 - 4.1.1.52 - S ko:K22213 - ko00000,ko01000 Amidohydrolase
HLJEPGAF_02403 6.12e-166 - - - E - - - lipolytic protein G-D-S-L family
HLJEPGAF_02404 6.92e-206 yicL - - EG - - - EamA-like transporter family
HLJEPGAF_02405 2.1e-116 - - - T - - - ECF transporter, substrate-specific component
HLJEPGAF_02406 1.06e-16 - - - - - - - -
HLJEPGAF_02407 1.96e-21 ytgB - - S - - - Transglycosylase associated protein
HLJEPGAF_02408 0.0 katA 1.11.1.6 - C ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 Belongs to the catalase family
HLJEPGAF_02409 1.32e-101 nrp - - K ko:K16509 - ko00000 ArsC family
HLJEPGAF_02410 7.42e-174 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HLJEPGAF_02411 3.78e-212 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HLJEPGAF_02412 9.62e-19 - - - - - - - -
HLJEPGAF_02413 1.51e-85 - - - KOT ko:K07813 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01002 May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
HLJEPGAF_02414 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
HLJEPGAF_02416 8.76e-72 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HLJEPGAF_02417 6.67e-165 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HLJEPGAF_02418 0.0 pox4 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HLJEPGAF_02419 5.03e-95 - - - K - - - Transcriptional regulator
HLJEPGAF_02420 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HLJEPGAF_02421 6.96e-83 pts38A 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
HLJEPGAF_02422 5.88e-233 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
HLJEPGAF_02423 1.23e-129 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
HLJEPGAF_02424 3.33e-113 srlM1 - - K - - - Glucitol operon activator protein (GutM)
HLJEPGAF_02425 0.0 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
HLJEPGAF_02426 1.56e-185 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
HLJEPGAF_02427 2.53e-209 rbsU - - U ko:K06216 - ko00000,ko02000 ribose uptake protein RbsU
HLJEPGAF_02428 2.03e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HLJEPGAF_02429 4.52e-209 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HLJEPGAF_02430 1.88e-240 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HLJEPGAF_02431 3.36e-06 - - - K ko:K07726 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
HLJEPGAF_02432 2.46e-08 - - - - - - - -
HLJEPGAF_02433 1.23e-26 - - - - - - - -
HLJEPGAF_02434 1.1e-147 - - - K ko:K03489 - ko00000,ko03000 UTRA
HLJEPGAF_02435 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HLJEPGAF_02436 9.2e-317 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLJEPGAF_02437 2.09e-85 - - - - - - - -
HLJEPGAF_02438 2.85e-83 - - - S - - - Protein of unknown function (DUF1093)
HLJEPGAF_02439 2.15e-281 - - - S - - - Membrane
HLJEPGAF_02440 1.04e-59 - - - S - - - Protein of unknown function (DUF3781)
HLJEPGAF_02441 1.31e-139 yoaZ - - S - - - intracellular protease amidase
HLJEPGAF_02442 2.33e-56 - - - K - - - HxlR-like helix-turn-helix
HLJEPGAF_02443 5.36e-76 - - - - - - - -
HLJEPGAF_02444 1.46e-81 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HLJEPGAF_02445 5.31e-66 - - - K - - - Helix-turn-helix domain
HLJEPGAF_02446 3.17e-258 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
HLJEPGAF_02447 2e-62 - - - K - - - Helix-turn-helix domain
HLJEPGAF_02448 3.87e-115 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HLJEPGAF_02449 1.06e-72 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HLJEPGAF_02450 5.53e-114 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HLJEPGAF_02451 6.79e-53 - - - - - - - -
HLJEPGAF_02452 5.06e-168 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HLJEPGAF_02453 1.6e-233 ydbI - - K - - - AI-2E family transporter
HLJEPGAF_02454 9.28e-271 xylR - - GK - - - ROK family
HLJEPGAF_02455 2.92e-143 - - - - - - - -
HLJEPGAF_02456 3.66e-295 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
HLJEPGAF_02457 3.32e-210 - - - - - - - -
HLJEPGAF_02458 1.86e-256 pkn2 - - KLT - - - Protein tyrosine kinase
HLJEPGAF_02459 9.58e-35 - - - S - - - Protein of unknown function (DUF4064)
HLJEPGAF_02460 2.47e-125 - - - S - - - Domain of unknown function (DUF4352)
HLJEPGAF_02461 9.69e-99 - - - S - - - Psort location Cytoplasmic, score
HLJEPGAF_02462 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HLJEPGAF_02463 3.51e-252 galM3 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HLJEPGAF_02464 3.69e-232 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HLJEPGAF_02465 1.42e-245 tas3 - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
HLJEPGAF_02466 2.86e-85 - - - S - - - pyridoxamine 5-phosphate
HLJEPGAF_02467 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HLJEPGAF_02468 1.23e-228 apbE3 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HLJEPGAF_02469 5.56e-167 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HLJEPGAF_02470 1.33e-274 - - - G - - - Transporter
HLJEPGAF_02471 1.66e-215 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HLJEPGAF_02472 5.79e-209 - - - K - - - Transcriptional regulator, LysR family
HLJEPGAF_02473 5.78e-269 - - - G - - - Major Facilitator Superfamily
HLJEPGAF_02474 2.97e-83 - - - - - - - -
HLJEPGAF_02475 1.78e-198 estA - - S - - - Putative esterase
HLJEPGAF_02476 5.44e-174 - - - K - - - UTRA domain
HLJEPGAF_02477 0.0 pts29C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLJEPGAF_02478 1.67e-208 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HLJEPGAF_02479 6.87e-202 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
HLJEPGAF_02480 2.26e-269 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
HLJEPGAF_02481 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HLJEPGAF_02482 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HLJEPGAF_02483 3.72e-200 bglG4 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HLJEPGAF_02484 2.62e-216 pbg9 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HLJEPGAF_02485 5.6e-292 - - - S - - - Pyridine nucleotide-disulphide oxidoreductase
HLJEPGAF_02486 2.13e-159 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HLJEPGAF_02487 1.86e-210 nanA 4.1.3.3 - EM ko:K01639 ko00520,map00520 ko00000,ko00001,ko01000 Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
HLJEPGAF_02488 1.33e-196 nanK - - GK - - - ROK family
HLJEPGAF_02489 9.03e-173 - - - G - - - Xylose isomerase domain protein TIM barrel
HLJEPGAF_02490 4.01e-263 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HLJEPGAF_02491 0.0 - - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HLJEPGAF_02492 3.89e-205 - - - I - - - alpha/beta hydrolase fold
HLJEPGAF_02493 3.21e-127 - - - I - - - alpha/beta hydrolase fold
HLJEPGAF_02494 8.16e-48 - - - I - - - alpha/beta hydrolase fold
HLJEPGAF_02495 6.47e-95 - - - S - - - Protein of unknown function (DUF1694)
HLJEPGAF_02496 3.76e-180 - - - K - - - Helix-turn-helix domain, rpiR family
HLJEPGAF_02497 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
HLJEPGAF_02498 1.83e-146 - - - K ko:K02444 - ko00000,ko03000 DeoR C terminal sensor domain
HLJEPGAF_02499 3.99e-106 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HLJEPGAF_02500 6e-60 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HLJEPGAF_02501 8.37e-296 gatC - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
HLJEPGAF_02502 5.26e-247 - 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
HLJEPGAF_02503 9.14e-146 gph3 - - S - - - Haloacid dehalogenase-like hydrolase
HLJEPGAF_02504 0.0 - - - G ko:K03483 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HLJEPGAF_02505 1.58e-101 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HLJEPGAF_02506 7.29e-61 ulaB 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system galactitol-specific IIB component
HLJEPGAF_02507 1.17e-305 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
HLJEPGAF_02508 1.68e-146 tal 2.2.1.2 - F ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HLJEPGAF_02509 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HLJEPGAF_02510 1.74e-184 yxeH - - S - - - hydrolase
HLJEPGAF_02511 5.61e-39 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HLJEPGAF_02512 1.05e-225 hicD1 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HLJEPGAF_02513 8.95e-60 - - - - - - - -
HLJEPGAF_02514 1.99e-26 zmp1 - - O - - - Zinc-dependent metalloprotease
HLJEPGAF_02515 8.36e-154 rpiA2 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HLJEPGAF_02516 0.0 sufI - - Q - - - Multicopper oxidase
HLJEPGAF_02517 5.34e-72 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
HLJEPGAF_02518 1.31e-124 yxkA - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
HLJEPGAF_02519 1.54e-292 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
HLJEPGAF_02520 5.89e-108 - - - K - - - Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HLJEPGAF_02521 2.16e-103 - - - - - - - -
HLJEPGAF_02522 2.32e-101 accB3 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HLJEPGAF_02523 1.49e-223 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
HLJEPGAF_02524 2.42e-207 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HLJEPGAF_02525 4.06e-102 - 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA-DNA hybrid ribonuclease activity
HLJEPGAF_02526 0.0 proWX - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HLJEPGAF_02527 2.7e-230 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HLJEPGAF_02528 0.0 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
HLJEPGAF_02529 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HLJEPGAF_02530 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
HLJEPGAF_02531 2.14e-174 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HLJEPGAF_02532 0.0 - - - M - - - domain protein
HLJEPGAF_02533 6.75e-85 - - - M - - - dTDP-4-dehydrorhamnose reductase activity
HLJEPGAF_02534 1.82e-34 - - - S - - - Immunity protein 74
HLJEPGAF_02535 1.89e-169 - - - S - - - KR domain
HLJEPGAF_02536 2.56e-83 - - - K - - - HxlR-like helix-turn-helix
HLJEPGAF_02537 1.62e-62 - - - S - - - Domain of unknown function (DUF1905)
HLJEPGAF_02538 0.0 - - - M - - - Glycosyl hydrolases family 25
HLJEPGAF_02539 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HLJEPGAF_02540 2.09e-213 - - - GM - - - NmrA-like family
HLJEPGAF_02541 1.15e-124 - - - K - - - Bacterial regulatory proteins, tetR family
HLJEPGAF_02542 5.93e-281 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HLJEPGAF_02543 6.58e-173 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HLJEPGAF_02544 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HLJEPGAF_02545 7.81e-148 - - - M - - - ErfK YbiS YcfS YnhG
HLJEPGAF_02546 5.78e-269 - - - EGP - - - Major Facilitator
HLJEPGAF_02547 3.25e-81 ytcD - - K - - - Transcriptional regulator, HxlR family
HLJEPGAF_02548 1.06e-149 - - - S - - - Haloacid dehalogenase-like hydrolase
HLJEPGAF_02549 4.13e-157 - - - - - - - -
HLJEPGAF_02550 7.39e-300 - - - NU - - - Mycoplasma protein of unknown function, DUF285
HLJEPGAF_02551 1.47e-83 - - - - - - - -
HLJEPGAF_02552 3.15e-130 - - - S - - - WxL domain surface cell wall-binding
HLJEPGAF_02553 2.16e-241 ynjC - - S - - - Cell surface protein
HLJEPGAF_02554 2.63e-146 - - - S - - - GyrI-like small molecule binding domain
HLJEPGAF_02555 5.83e-87 - - - S - - - Iron-sulphur cluster biosynthesis
HLJEPGAF_02556 6.57e-226 - - - C - - - Alcohol dehydrogenase GroES-like domain
HLJEPGAF_02557 2.56e-131 - - - T - - - Diguanylate cyclase, GGDEF domain
HLJEPGAF_02558 8.07e-163 - - - T - - - Putative diguanylate phosphodiesterase
HLJEPGAF_02559 6.36e-134 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HLJEPGAF_02560 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
HLJEPGAF_02561 1.56e-108 - - - - - - - -
HLJEPGAF_02562 5.97e-96 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
HLJEPGAF_02563 9.2e-243 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HLJEPGAF_02564 7.3e-245 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HLJEPGAF_02565 3.7e-30 - - - - - - - -
HLJEPGAF_02566 1.38e-131 - - - - - - - -
HLJEPGAF_02567 3.46e-210 - - - K - - - LysR substrate binding domain
HLJEPGAF_02568 4.34e-314 - - - P - - - Sodium:sulfate symporter transmembrane region
HLJEPGAF_02569 0.0 - 4.1.1.98 - H ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HLJEPGAF_02570 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
HLJEPGAF_02571 1.37e-182 - - - S - - - zinc-ribbon domain
HLJEPGAF_02573 4.29e-50 - - - - - - - -
HLJEPGAF_02574 1.4e-137 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
HLJEPGAF_02575 1.4e-20 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
HLJEPGAF_02576 2.35e-231 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
HLJEPGAF_02577 0.0 - - - I - - - acetylesterase activity
HLJEPGAF_02578 6.08e-78 - - - M - - - Collagen binding domain
HLJEPGAF_02593 1.08e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
HLJEPGAF_02594 2.81e-178 yhfI - - S - - - Metallo-beta-lactamase superfamily
HLJEPGAF_02595 9.28e-89 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HLJEPGAF_02596 7.12e-170 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HLJEPGAF_02597 1.64e-17 coiA - - S ko:K06198 - ko00000 Competence protein
HLJEPGAF_02598 1.52e-231 coiA - - S ko:K06198 - ko00000 Competence protein
HLJEPGAF_02599 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
HLJEPGAF_02600 2.24e-148 yjbH - - Q - - - Thioredoxin
HLJEPGAF_02601 1.83e-156 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
HLJEPGAF_02602 1.29e-193 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HLJEPGAF_02603 6.31e-222 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HLJEPGAF_02604 7.21e-150 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
HLJEPGAF_02605 1.6e-246 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
HLJEPGAF_02606 2.68e-75 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
HLJEPGAF_02607 9.52e-264 XK27_05220 - - S - - - AI-2E family transporter
HLJEPGAF_02608 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HLJEPGAF_02609 1.12e-207 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
HLJEPGAF_02611 3.59e-301 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HLJEPGAF_02612 2.5e-147 - - - S ko:K07118 - ko00000 NAD(P)H-binding
HLJEPGAF_02613 4.97e-124 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HLJEPGAF_02614 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HLJEPGAF_02615 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HLJEPGAF_02616 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HLJEPGAF_02617 1.29e-148 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HLJEPGAF_02618 2.94e-71 ytzB - - S - - - Peptidase propeptide and YPEB domain
HLJEPGAF_02619 2.8e-155 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HLJEPGAF_02620 7.24e-197 ytmP - - M - - - Choline/ethanolamine kinase
HLJEPGAF_02621 8.17e-285 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HLJEPGAF_02622 1.1e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HLJEPGAF_02623 3.6e-106 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
HLJEPGAF_02624 6.76e-73 - - - - - - - -
HLJEPGAF_02625 1.09e-196 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HLJEPGAF_02626 1.78e-153 draG - - O - - - ADP-ribosylglycohydrolase
HLJEPGAF_02627 5.76e-135 - - - S - - - WxL domain surface cell wall-binding
HLJEPGAF_02628 2.82e-138 - - - S - - - WxL domain surface cell wall-binding
HLJEPGAF_02629 1.94e-247 - - - S - - - Fn3-like domain
HLJEPGAF_02630 1.65e-80 - - - - - - - -
HLJEPGAF_02631 0.0 - - - - - - - -
HLJEPGAF_02632 4.26e-308 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
HLJEPGAF_02633 0.0 acdH 1.1.1.1, 1.2.1.10, 1.2.1.87 - C ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
HLJEPGAF_02634 8.16e-207 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
HLJEPGAF_02636 2.75e-304 xylP1 - - G - - - MFS/sugar transport protein
HLJEPGAF_02637 5.81e-170 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
HLJEPGAF_02638 3.48e-40 - - - - - - - -
HLJEPGAF_02639 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HLJEPGAF_02640 6.4e-54 - - - - - - - -
HLJEPGAF_02641 7.31e-122 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HLJEPGAF_02642 6.8e-224 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HLJEPGAF_02643 3.08e-81 - - - S - - - CHY zinc finger
HLJEPGAF_02644 3.51e-281 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HLJEPGAF_02645 1.57e-280 - - - - - - - -
HLJEPGAF_02646 1.15e-198 tagG - - U ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
HLJEPGAF_02647 9.42e-258 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HLJEPGAF_02648 3.93e-59 - - - - - - - -
HLJEPGAF_02649 4.63e-119 - - - K - - - Transcriptional regulator PadR-like family
HLJEPGAF_02650 0.0 - - - P - - - Major Facilitator Superfamily
HLJEPGAF_02651 3.5e-307 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
HLJEPGAF_02652 1.08e-243 - - - - - - - -
HLJEPGAF_02653 1.85e-208 - - - V ko:K01990,ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HLJEPGAF_02654 5.05e-79 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
HLJEPGAF_02655 2.06e-30 - - - - - - - -
HLJEPGAF_02656 2.14e-117 - - - K - - - acetyltransferase
HLJEPGAF_02657 1.88e-111 - - - K - - - GNAT family
HLJEPGAF_02658 8.08e-110 - - - S - - - ASCH
HLJEPGAF_02659 3.68e-125 - - - K - - - Cupin domain
HLJEPGAF_02660 8.8e-264 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HLJEPGAF_02661 6.34e-190 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HLJEPGAF_02662 1.31e-179 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HLJEPGAF_02663 3.07e-264 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HLJEPGAF_02664 2.18e-53 - - - - - - - -
HLJEPGAF_02665 9.59e-288 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HLJEPGAF_02666 1.02e-98 - - - K - - - Transcriptional regulator
HLJEPGAF_02667 9.81e-33 - - - S ko:K02348 - ko00000 GNAT family
HLJEPGAF_02668 3.74e-284 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HLJEPGAF_02669 3.01e-75 - - - - - - - -
HLJEPGAF_02670 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
HLJEPGAF_02671 3.27e-168 - - - - - - - -
HLJEPGAF_02672 4.29e-227 - - - - - - - -
HLJEPGAF_02673 4.2e-88 gcsH1 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Glycine cleavage H-protein
HLJEPGAF_02674 7.81e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HLJEPGAF_02675 3.04e-297 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HLJEPGAF_02676 1.79e-243 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HLJEPGAF_02677 3.44e-204 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HLJEPGAF_02678 1.88e-251 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HLJEPGAF_02679 1.54e-141 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HLJEPGAF_02680 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
HLJEPGAF_02681 3.04e-174 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
HLJEPGAF_02682 4.07e-249 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HLJEPGAF_02683 3.76e-245 ampC - - V - - - Beta-lactamase
HLJEPGAF_02684 8.57e-41 - - - - - - - -
HLJEPGAF_02685 1.9e-260 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HLJEPGAF_02686 1.33e-77 - - - - - - - -
HLJEPGAF_02687 1.08e-181 - - - - - - - -
HLJEPGAF_02688 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
HLJEPGAF_02689 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
HLJEPGAF_02690 1.81e-85 yxeA - - S - - - Protein of unknown function (DUF1093)
HLJEPGAF_02691 2.91e-177 icaB - - G - - - Polysaccharide deacetylase
HLJEPGAF_02693 2.07e-40 - - - - - - - -
HLJEPGAF_02694 7.92e-140 - - - S ko:K07090 - ko00000 membrane transporter protein
HLJEPGAF_02695 5.93e-73 - - - S - - - branched-chain amino acid
HLJEPGAF_02696 2.05e-167 - - - E - - - branched-chain amino acid
HLJEPGAF_02697 1.6e-114 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
HLJEPGAF_02698 3.1e-304 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HLJEPGAF_02699 5.61e-273 hpk31 - - T - - - Histidine kinase
HLJEPGAF_02700 1.14e-159 vanR - - K - - - response regulator
HLJEPGAF_02701 2.4e-161 - - - S - - - Protein of unknown function (DUF1275)
HLJEPGAF_02702 3.3e-208 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HLJEPGAF_02703 1.42e-269 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HLJEPGAF_02704 3.49e-160 - - - S - - - Protein of unknown function (DUF1129)
HLJEPGAF_02705 6.6e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HLJEPGAF_02706 1.4e-40 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
HLJEPGAF_02707 7.16e-201 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HLJEPGAF_02708 1.01e-175 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
HLJEPGAF_02709 8.63e-191 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HLJEPGAF_02710 1.81e-168 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
HLJEPGAF_02711 4.76e-288 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
HLJEPGAF_02712 2.87e-270 yfhO - - S - - - Bacterial membrane protein YfhO
HLJEPGAF_02713 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
HLJEPGAF_02714 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HLJEPGAF_02715 1.25e-86 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HLJEPGAF_02716 6.46e-221 tnp2 - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
HLJEPGAF_02717 1.04e-98 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLJEPGAF_02719 0.0 prtP 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HLJEPGAF_02720 1.53e-26 - - - - - - - -
HLJEPGAF_02721 4.95e-103 - - - - - - - -
HLJEPGAF_02723 1.32e-224 - - - M - - - Peptidase family S41
HLJEPGAF_02724 7.34e-124 - - - K - - - Helix-turn-helix domain
HLJEPGAF_02725 5.05e-05 - - - S - - - FRG
HLJEPGAF_02727 1.92e-18 mpr - - E - - - Trypsin-like serine protease
HLJEPGAF_02728 3.53e-38 - - - S - - - Psort location CytoplasmicMembrane, score
HLJEPGAF_02730 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HLJEPGAF_02731 1.32e-57 - - - - - - - -
HLJEPGAF_02732 1.98e-72 repA - - S - - - Replication initiator protein A
HLJEPGAF_02733 2.78e-231 - - - U - - - Relaxase/Mobilisation nuclease domain
HLJEPGAF_02734 9.13e-70 - - - S - - - Bacterial mobilisation protein (MobC)
HLJEPGAF_02735 3.03e-49 - - - K - - - sequence-specific DNA binding
HLJEPGAF_02736 2.08e-60 - - - S - - - Phage derived protein Gp49-like (DUF891)
HLJEPGAF_02737 1.26e-137 - - - L - - - Integrase
HLJEPGAF_02738 1.11e-59 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
HLJEPGAF_02739 9.04e-78 - - - S - - - Bacterial toxin of type II toxin-antitoxin system, YafQ
HLJEPGAF_02740 7.1e-81 - - - S - - - Protein of unknown function (DUF2992)
HLJEPGAF_02741 1.4e-13 - - - K - - - Helix-turn-helix XRE-family like proteins
HLJEPGAF_02742 6.34e-39 - - - - - - - -
HLJEPGAF_02743 0.0 - - - S - - - MucBP domain
HLJEPGAF_02744 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HLJEPGAF_02745 4.33e-205 - - - K - - - LysR substrate binding domain
HLJEPGAF_02746 1.85e-201 - 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 NADH pyrophosphatase zinc ribbon domain
HLJEPGAF_02747 0.0 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
HLJEPGAF_02748 0.0 lepA2 - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HLJEPGAF_02749 6.88e-152 - - - K - - - Bacterial regulatory proteins, tetR family
HLJEPGAF_02750 7.19e-89 - - - NU - - - Mycoplasma protein of unknown function, DUF285
HLJEPGAF_02751 3.53e-65 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HLJEPGAF_02752 2.63e-44 - - - - - - - -
HLJEPGAF_02753 4.33e-162 hsdS 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain protein
HLJEPGAF_02754 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
HLJEPGAF_02755 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
HLJEPGAF_02756 5.79e-08 - - - - - - - -
HLJEPGAF_02757 8.94e-91 - - - - - - - -
HLJEPGAF_02758 9.45e-299 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HLJEPGAF_02759 3.74e-302 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HLJEPGAF_02760 2.83e-206 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HLJEPGAF_02761 2.91e-190 malA - - S - - - maltodextrose utilization protein MalA
HLJEPGAF_02762 0.0 malS 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Glycogen debranching enzyme, glucanotransferase domain
HLJEPGAF_02763 2.44e-267 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HLJEPGAF_02764 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HLJEPGAF_02765 0.0 - 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 85
HLJEPGAF_02766 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
HLJEPGAF_02767 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HLJEPGAF_02768 1.08e-221 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
HLJEPGAF_02769 0.0 treP 2.4.1.64 GH65 G ko:K05342 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HLJEPGAF_02770 1.3e-203 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HLJEPGAF_02771 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HLJEPGAF_02772 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HLJEPGAF_02773 3.26e-102 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
HLJEPGAF_02774 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
HLJEPGAF_02775 2.66e-132 - - - G - - - Glycogen debranching enzyme
HLJEPGAF_02776 5.6e-14 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
HLJEPGAF_02777 6.72e-208 yjdB - - S - - - Domain of unknown function (DUF4767)
HLJEPGAF_02778 2.02e-192 yisK 3.7.1.5, 4.1.1.68 - Q ko:K05921,ko:K16164 ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Fumarylacetoacetate (FAA) hydrolase family
HLJEPGAF_02779 1.04e-94 asp2 - - S - - - Asp23 family, cell envelope-related function
HLJEPGAF_02780 1.1e-93 asp1 - - S - - - Asp23 family, cell envelope-related function
HLJEPGAF_02781 5.74e-32 - - - - - - - -
HLJEPGAF_02782 1.37e-116 - - - - - - - -
HLJEPGAF_02783 1.81e-50 ydaS - - S - - - Transglycosylase associated protein
HLJEPGAF_02784 0.0 XK27_09800 - - I - - - Acyltransferase family
HLJEPGAF_02785 1.71e-59 - - - S - - - MORN repeat
HLJEPGAF_02786 3.39e-52 - - - S - - - Cysteine-rich secretory protein family
HLJEPGAF_02787 5.3e-157 - - - E - - - GDSL-like Lipase/Acylhydrolase family
HLJEPGAF_02788 4.29e-101 - - - - - - - -
HLJEPGAF_02789 5.09e-51 - - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
HLJEPGAF_02790 2.42e-127 - - - FG - - - HIT domain
HLJEPGAF_02791 4.27e-223 ydhF - - S - - - Aldo keto reductase
HLJEPGAF_02792 5.17e-70 - - - S - - - Pfam:DUF59
HLJEPGAF_02793 4.56e-206 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HLJEPGAF_02794 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
HLJEPGAF_02795 1.87e-249 - - - V - - - Beta-lactamase
HLJEPGAF_02796 3.74e-125 - - - V - - - VanZ like family
HLJEPGAF_02797 6.02e-137 - - - S - - - WxL domain surface cell wall-binding
HLJEPGAF_02798 7.81e-241 - - - S - - - Cell surface protein
HLJEPGAF_02799 3.15e-98 - - - - - - - -
HLJEPGAF_02800 0.0 - - - - - - - -
HLJEPGAF_02801 3.56e-288 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HLJEPGAF_02802 2.97e-51 - - - S ko:K07343 - ko00000 TfoX C-terminal domain
HLJEPGAF_02803 2.81e-181 - - - K - - - Helix-turn-helix domain
HLJEPGAF_02804 4.31e-179 - - - - - - - -
HLJEPGAF_02805 2.82e-236 - - - S - - - DUF218 domain
HLJEPGAF_02806 3.26e-228 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HLJEPGAF_02807 9.06e-193 bla1 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
HLJEPGAF_02808 5.78e-292 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HLJEPGAF_02809 1.96e-189 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
HLJEPGAF_02810 5.3e-49 - - - - - - - -
HLJEPGAF_02811 2.95e-57 - - - S - - - ankyrin repeats
HLJEPGAF_02812 5.13e-119 - - - S - - - ECF-type riboflavin transporter, S component
HLJEPGAF_02813 7.59e-64 - - - - - - - -
HLJEPGAF_02814 6.83e-274 yceI - - EGP ko:K08369 - ko00000,ko02000 Major Facilitator
HLJEPGAF_02815 8.05e-178 - - - F - - - NUDIX domain
HLJEPGAF_02816 2.68e-32 - - - - - - - -
HLJEPGAF_02818 8.51e-209 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HLJEPGAF_02819 1.23e-222 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 NlpC/P60 family
HLJEPGAF_02820 3.43e-106 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
HLJEPGAF_02821 2.29e-48 - - - - - - - -
HLJEPGAF_02822 4.54e-45 - - - - - - - -
HLJEPGAF_02823 9.39e-277 - - - T - - - diguanylate cyclase
HLJEPGAF_02825 2.55e-218 - - - EG - - - EamA-like transporter family
HLJEPGAF_02826 1.06e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
HLJEPGAF_02827 2.12e-308 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
HLJEPGAF_02828 1.45e-173 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
HLJEPGAF_02829 0.0 yclK - - T - - - Histidine kinase
HLJEPGAF_02830 5.23e-277 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 S-adenosylmethionine-dependent methyltransferase
HLJEPGAF_02831 2.51e-200 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
HLJEPGAF_02832 6.66e-115 - - - - - - - -
HLJEPGAF_02833 2.29e-225 - - - L - - - Initiator Replication protein
HLJEPGAF_02834 3.67e-41 - - - - - - - -
HLJEPGAF_02835 1.87e-139 - - - L - - - Integrase
HLJEPGAF_02836 4.17e-55 - - - K - - - prlF antitoxin for toxin YhaV_toxin
HLJEPGAF_02837 1.03e-77 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
HLJEPGAF_02838 0.0 ybfG - - M - - - peptidoglycan-binding domain-containing protein
HLJEPGAF_02840 0.0 - 3.6.3.44 - P ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter transmembrane region
HLJEPGAF_02841 2.62e-76 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HLJEPGAF_02842 1.89e-254 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HLJEPGAF_02843 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HLJEPGAF_02844 2.1e-33 - - - - - - - -
HLJEPGAF_02845 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HLJEPGAF_02846 9.51e-142 XK27_07075 - - V ko:K07052 - ko00000 CAAX protease self-immunity
HLJEPGAF_02847 1.07e-74 - - - K - - - HxlR-like helix-turn-helix
HLJEPGAF_02848 2.13e-167 - - - L - - - Helix-turn-helix domain
HLJEPGAF_02849 4.73e-206 - - - L ko:K07497 - ko00000 hmm pf00665
HLJEPGAF_02850 6.16e-298 yceJ - - EGP ko:K08221 - ko00000,ko02000 transporter
HLJEPGAF_02851 5.87e-51 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
HLJEPGAF_02852 1.01e-117 ydhK - - M - - - Protein of unknown function (DUF1541)
HLJEPGAF_02853 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
HLJEPGAF_02854 4.2e-22 - - - - - - - -
HLJEPGAF_02855 1.54e-125 - - - K - - - Bacterial regulatory proteins, tetR family
HLJEPGAF_02856 2.1e-78 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
HLJEPGAF_02857 2.64e-129 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
HLJEPGAF_02858 2.43e-241 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
HLJEPGAF_02860 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
HLJEPGAF_02861 5.49e-237 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
HLJEPGAF_02862 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HLJEPGAF_02863 0.0 traA - - L - - - MobA MobL family protein
HLJEPGAF_02864 0.0 merA 1.16.1.1 - C ko:K00520,ko:K21739 - ko00000,ko01000 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HLJEPGAF_02865 2.78e-80 - - - M - - - Cna protein B-type domain
HLJEPGAF_02868 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
HLJEPGAF_02869 1.61e-74 mleR - - K - - - LysR substrate binding domain
HLJEPGAF_02870 3.55e-169 - - - K - - - LysR family
HLJEPGAF_02871 0.0 - - - C - - - FMN_bind
HLJEPGAF_02872 2.17e-304 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HLJEPGAF_02873 3.99e-101 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HLJEPGAF_02874 7.43e-130 padR - - K - - - Virulence activator alpha C-term
HLJEPGAF_02875 2.51e-103 - - - T - - - Universal stress protein family
HLJEPGAF_02876 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
HLJEPGAF_02878 7.39e-83 - - - G - - - COG0662 Mannose-6-phosphate isomerase
HLJEPGAF_02879 2.85e-57 - - - - - - - -
HLJEPGAF_02880 2.06e-66 ykoF - - S - - - YKOF-related Family
HLJEPGAF_02881 5.63e-15 - - - E - - - glutamine synthetase
HLJEPGAF_02882 9.73e-245 - - - E - - - glutamine synthetase
HLJEPGAF_02883 3.2e-76 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
HLJEPGAF_02884 3.16e-59 - - - T ko:K07172 - ko00000,ko02048 Antidote-toxin recognition MazE, bacterial antitoxin
HLJEPGAF_02885 9.24e-140 - - - L - - - Integrase
HLJEPGAF_02886 3.72e-21 - - - - - - - -
HLJEPGAF_02887 1.19e-124 - - - L - - - Resolvase, N terminal domain
HLJEPGAF_02888 7.8e-75 usp2 - - T - - - Belongs to the universal stress protein A family
HLJEPGAF_02889 9.57e-315 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HLJEPGAF_02890 2.37e-49 - - - K ko:K03709 - ko00000,ko03000 Helix-turn-helix diphteria tox regulatory element
HLJEPGAF_02892 1.48e-81 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HLJEPGAF_02893 5.32e-298 aspD 4.1.1.12 - E ko:K09758 ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230 ko00000,ko00001,ko01000 Aminotransferase class I and II
HLJEPGAF_02894 9.33e-249 - - - U ko:K07085 - ko00000 Predicted Permease Membrane Region
HLJEPGAF_02895 6.47e-10 - - - P - - - Cation efflux family
HLJEPGAF_02896 8.86e-35 - - - - - - - -
HLJEPGAF_02897 0.0 sufI - - Q - - - Multicopper oxidase
HLJEPGAF_02898 2.44e-303 - - - EGP - - - Major Facilitator Superfamily
HLJEPGAF_02899 1.89e-71 - - - - - - - -
HLJEPGAF_02900 7.86e-68 - - - L - - - Transposase IS66 family
HLJEPGAF_02901 2.89e-256 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
HLJEPGAF_02902 3.9e-34 - - - - - - - -
HLJEPGAF_02903 5.03e-75 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
HLJEPGAF_02904 4.16e-06 - - - S - - - Transposase C of IS166 homeodomain
HLJEPGAF_02905 2.09e-151 - - - - - - - -
HLJEPGAF_02906 1.16e-84 - - - - - - - -
HLJEPGAF_02907 1.95e-25 - - - - - - - -
HLJEPGAF_02908 3.1e-172 repA - - S - - - Replication initiator protein A
HLJEPGAF_02909 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HLJEPGAF_02910 9.4e-148 mdt(A) - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Major facilitator Superfamily
HLJEPGAF_02911 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HLJEPGAF_02912 1.28e-98 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Transcriptional regulator
HLJEPGAF_02915 4.87e-45 - - - - - - - -
HLJEPGAF_02916 8.69e-185 - - - D - - - AAA domain
HLJEPGAF_02917 5.62e-49 kdpE - - KT ko:K02483,ko:K07667 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
HLJEPGAF_02918 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
HLJEPGAF_02919 1.74e-72 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HLJEPGAF_02920 5.17e-70 - - - S - - - Nitroreductase
HLJEPGAF_02921 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HLJEPGAF_02922 4.21e-174 bgaR - - K - - - helix_turn_helix, arabinose operon control protein
HLJEPGAF_02923 3.79e-26 - - - - - - - -
HLJEPGAF_02924 5.41e-89 - - - C - - - lyase activity
HLJEPGAF_02925 4.31e-196 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
HLJEPGAF_02926 1.39e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HLJEPGAF_02927 3.23e-150 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
HLJEPGAF_02928 4.27e-146 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
HLJEPGAF_02929 3.77e-278 - - - EGP - - - Major Facilitator
HLJEPGAF_02930 1.62e-150 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HLJEPGAF_02931 8.61e-19 - 3.3.1.1 - H ko:K01251 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 adenosylhomocysteinase activity
HLJEPGAF_02933 6.89e-190 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
HLJEPGAF_02934 1.95e-62 - - - S - - - Family of unknown function (DUF5388)
HLJEPGAF_02936 7.57e-122 - - - K - - - Bacterial regulatory proteins, tetR family
HLJEPGAF_02937 3.47e-244 - 1.1.1.219 - GM ko:K00091 - ko00000,ko01000 Male sterility protein
HLJEPGAF_02938 1.27e-129 - - - S - - - Protein of unknown function (DUF1211)
HLJEPGAF_02939 9.24e-140 - - - K ko:K06977 - ko00000 acetyltransferase
HLJEPGAF_02940 0.0 - - - S - - - ABC transporter, ATP-binding protein
HLJEPGAF_02941 5.11e-59 - - - S - - - Bacteriophage holin
HLJEPGAF_02942 2.93e-73 - - - V - - - Abortive infection bacteriophage resistance protein
HLJEPGAF_02943 1.39e-36 - - - - - - - -
HLJEPGAF_02944 2.83e-58 - - - L ko:K07473 - ko00000,ko02048 Addiction module antitoxin, RelB DinJ family
HLJEPGAF_02945 6.45e-111 - - - - - - - -
HLJEPGAF_02946 8.5e-55 - - - - - - - -
HLJEPGAF_02947 1.34e-34 - - - - - - - -
HLJEPGAF_02948 2.62e-160 - - - S - - - Phage Mu protein F like protein
HLJEPGAF_02949 3.62e-22 ytgB - - S - - - Transglycosylase associated protein
HLJEPGAF_02950 9.4e-122 - - - L - - - 4.5 Transposon and IS
HLJEPGAF_02951 1.15e-52 - - - L ko:K07483 - ko00000 Transposase
HLJEPGAF_02953 5.15e-174 - - - L - - - Replication protein
HLJEPGAF_02954 6.03e-36 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLJEPGAF_02955 3.11e-17 - - - S - - - protein with an alpha beta hydrolase fold
HLJEPGAF_02956 2.03e-31 - - - S - - - Family of unknown function (DUF5388)
HLJEPGAF_02957 1.18e-184 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
HLJEPGAF_02958 3.46e-267 mccF - - V - - - LD-carboxypeptidase
HLJEPGAF_02959 1.66e-101 - - - K - - - Acetyltransferase (GNAT) domain
HLJEPGAF_02961 6.13e-127 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
HLJEPGAF_02962 9.51e-135 - - - - - - - -
HLJEPGAF_02963 3.72e-14 icaA - - M - - - Glycosyl transferase family group 2
HLJEPGAF_02964 1.32e-107 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
HLJEPGAF_02965 2.26e-39 - - - L - - - manually curated
HLJEPGAF_02966 1.18e-192 degV - - S - - - Uncharacterised protein, DegV family COG1307
HLJEPGAF_02967 4.05e-211 - - - L - - - PFAM Integrase catalytic region
HLJEPGAF_02968 1.95e-114 - - - L ko:K07483,ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Helix-turn-helix domain
HLJEPGAF_02969 2.67e-75 - - - - - - - -
HLJEPGAF_02970 2.54e-42 cspA - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HLJEPGAF_02971 4.19e-54 - - - - - - - -
HLJEPGAF_02972 1.18e-194 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
HLJEPGAF_02973 1.41e-163 - - - P - - - integral membrane protein, YkoY family
HLJEPGAF_02975 3.47e-47 tnpR - - L - - - Resolvase, N terminal domain
HLJEPGAF_02976 6.04e-43 - - - - - - - -
HLJEPGAF_02977 1.74e-18 - - - Q - - - Methyltransferase
HLJEPGAF_02978 2.43e-91 - - - S - - - Pyrimidine dimer DNA glycosylase
HLJEPGAF_02979 3.55e-76 - - - - - - - -
HLJEPGAF_02980 6.01e-49 - - - S - - - Bacteriophage holin
HLJEPGAF_02981 2.58e-147 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HLJEPGAF_02982 4.64e-18 - - - - - - - -
HLJEPGAF_02985 8.81e-48 - - - L - - - DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HLJEPGAF_02986 8.37e-108 - - - L - - - Transposase DDE domain
HLJEPGAF_02988 2.69e-105 - - - L ko:K07498 - ko00000 DDE domain

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)