ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
KBFHEIFM_00001 5.55e-301 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KBFHEIFM_00002 9.88e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KBFHEIFM_00003 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
KBFHEIFM_00004 7.52e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KBFHEIFM_00005 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
KBFHEIFM_00006 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KBFHEIFM_00007 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KBFHEIFM_00008 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
KBFHEIFM_00011 4.32e-232 yaaC - - S - - - YaaC-like Protein
KBFHEIFM_00012 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KBFHEIFM_00013 3.75e-316 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KBFHEIFM_00014 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KBFHEIFM_00015 3.34e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KBFHEIFM_00016 9.79e-296 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KBFHEIFM_00018 3.72e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
KBFHEIFM_00019 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
KBFHEIFM_00020 2.57e-276 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
KBFHEIFM_00021 5.64e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
KBFHEIFM_00022 1.05e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KBFHEIFM_00023 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KBFHEIFM_00024 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KBFHEIFM_00025 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KBFHEIFM_00026 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
KBFHEIFM_00027 6.2e-48 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
KBFHEIFM_00028 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
KBFHEIFM_00031 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
KBFHEIFM_00032 3.28e-133 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
KBFHEIFM_00033 5.05e-260 yaaN - - P - - - Belongs to the TelA family
KBFHEIFM_00034 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
KBFHEIFM_00035 1.34e-145 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KBFHEIFM_00036 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
KBFHEIFM_00037 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
KBFHEIFM_00038 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
KBFHEIFM_00039 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
KBFHEIFM_00040 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
KBFHEIFM_00041 1.14e-177 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
KBFHEIFM_00042 4.19e-65 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
KBFHEIFM_00043 7.26e-208 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KBFHEIFM_00044 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
KBFHEIFM_00045 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KBFHEIFM_00046 5.9e-184 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
KBFHEIFM_00047 4.1e-278 yabE - - T - - - protein conserved in bacteria
KBFHEIFM_00048 4.77e-124 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KBFHEIFM_00049 7.15e-199 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KBFHEIFM_00050 3.18e-198 yabG - - S ko:K06436 - ko00000 peptidase
KBFHEIFM_00051 5.32e-53 veg - - S - - - protein conserved in bacteria
KBFHEIFM_00052 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KBFHEIFM_00053 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
KBFHEIFM_00054 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
KBFHEIFM_00055 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
KBFHEIFM_00056 1.05e-308 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KBFHEIFM_00057 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KBFHEIFM_00058 6.9e-135 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KBFHEIFM_00059 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KBFHEIFM_00060 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
KBFHEIFM_00061 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KBFHEIFM_00062 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
KBFHEIFM_00063 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KBFHEIFM_00064 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
KBFHEIFM_00065 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KBFHEIFM_00066 1.91e-66 yabP - - S - - - Sporulation protein YabP
KBFHEIFM_00067 1.49e-137 yabQ - - S - - - spore cortex biosynthesis protein
KBFHEIFM_00068 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
KBFHEIFM_00069 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
KBFHEIFM_00072 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
KBFHEIFM_00073 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
KBFHEIFM_00074 1.15e-234 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
KBFHEIFM_00075 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KBFHEIFM_00076 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
KBFHEIFM_00077 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KBFHEIFM_00078 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KBFHEIFM_00079 4.53e-206 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KBFHEIFM_00080 5.49e-195 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
KBFHEIFM_00081 1.54e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
KBFHEIFM_00082 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KBFHEIFM_00083 1.72e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
KBFHEIFM_00084 4.4e-214 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
KBFHEIFM_00085 4.53e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KBFHEIFM_00086 4.62e-81 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KBFHEIFM_00087 4.56e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KBFHEIFM_00088 1.81e-41 yazB - - K - - - transcriptional
KBFHEIFM_00089 1.59e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KBFHEIFM_00090 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
KBFHEIFM_00091 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
KBFHEIFM_00101 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
KBFHEIFM_00102 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
KBFHEIFM_00103 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
KBFHEIFM_00104 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
KBFHEIFM_00105 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
KBFHEIFM_00106 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KBFHEIFM_00107 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KBFHEIFM_00108 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
KBFHEIFM_00109 1.75e-160 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KBFHEIFM_00110 2.59e-112 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
KBFHEIFM_00111 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KBFHEIFM_00112 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
KBFHEIFM_00113 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
KBFHEIFM_00114 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KBFHEIFM_00115 1.01e-172 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KBFHEIFM_00116 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
KBFHEIFM_00117 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
KBFHEIFM_00118 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KBFHEIFM_00119 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
KBFHEIFM_00120 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KBFHEIFM_00121 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KBFHEIFM_00122 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KBFHEIFM_00123 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KBFHEIFM_00124 5.1e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
KBFHEIFM_00125 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KBFHEIFM_00126 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KBFHEIFM_00127 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
KBFHEIFM_00128 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KBFHEIFM_00129 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KBFHEIFM_00130 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KBFHEIFM_00131 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KBFHEIFM_00132 3.58e-237 ybaC - - S - - - Alpha/beta hydrolase family
KBFHEIFM_00133 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
KBFHEIFM_00134 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KBFHEIFM_00135 7.98e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
KBFHEIFM_00136 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KBFHEIFM_00137 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KBFHEIFM_00138 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KBFHEIFM_00139 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KBFHEIFM_00140 5.9e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KBFHEIFM_00141 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KBFHEIFM_00142 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
KBFHEIFM_00143 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KBFHEIFM_00144 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KBFHEIFM_00145 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KBFHEIFM_00146 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KBFHEIFM_00147 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KBFHEIFM_00148 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KBFHEIFM_00149 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KBFHEIFM_00150 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KBFHEIFM_00151 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KBFHEIFM_00152 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
KBFHEIFM_00153 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
KBFHEIFM_00154 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KBFHEIFM_00155 2.51e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KBFHEIFM_00156 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
KBFHEIFM_00157 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KBFHEIFM_00158 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
KBFHEIFM_00159 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KBFHEIFM_00160 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KBFHEIFM_00161 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KBFHEIFM_00162 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
KBFHEIFM_00163 7.5e-200 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KBFHEIFM_00164 1.1e-196 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KBFHEIFM_00165 3.23e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KBFHEIFM_00166 4.16e-180 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KBFHEIFM_00167 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KBFHEIFM_00168 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
KBFHEIFM_00169 1.24e-185 ybaJ - - Q - - - Methyltransferase domain
KBFHEIFM_00170 5.12e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
KBFHEIFM_00171 9.05e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
KBFHEIFM_00172 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
KBFHEIFM_00173 1.04e-122 gerD - - - ko:K06294 - ko00000 -
KBFHEIFM_00174 5.95e-133 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
KBFHEIFM_00175 7.14e-180 pdaB - - G - - - Polysaccharide deacetylase
KBFHEIFM_00176 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
KBFHEIFM_00179 7.15e-101 - - - L - - - Phage integrase, N-terminal SAM-like domain
KBFHEIFM_00180 5.09e-31 xkdA - - E - - - IrrE N-terminal-like domain
KBFHEIFM_00182 1.41e-23 - - - K - - - Helix-turn-helix domain
KBFHEIFM_00184 1e-15 - - - S - - - Helix-turn-helix domain
KBFHEIFM_00185 3.29e-57 - - - - - - - -
KBFHEIFM_00189 8.24e-230 - - - D - - - nuclear chromosome segregation
KBFHEIFM_00191 4.43e-147 - - - L ko:K07455 - ko00000,ko03400 RecT family
KBFHEIFM_00192 6.93e-131 - - - S - - - Metallo-beta-lactamase superfamily
KBFHEIFM_00194 3.12e-33 - - - L - - - primosome component and related proteins
KBFHEIFM_00196 1.85e-227 - 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
KBFHEIFM_00199 1.03e-63 - 3.1.22.4 - - ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 -
KBFHEIFM_00200 4.91e-90 - - - - - - - -
KBFHEIFM_00204 2.22e-33 - - - - - - - -
KBFHEIFM_00209 1.3e-77 - - - - - - - -
KBFHEIFM_00210 4.94e-50 - - - - - - - -
KBFHEIFM_00212 3.56e-05 - - - - - - - -
KBFHEIFM_00215 2.47e-74 - - - K - - - DNA binding
KBFHEIFM_00216 1.23e-159 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
KBFHEIFM_00217 5.5e-42 - - - - - - - -
KBFHEIFM_00218 4.73e-110 - - - - - - - -
KBFHEIFM_00219 9.16e-297 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
KBFHEIFM_00220 2.77e-313 yqbA - - S - - - portal protein
KBFHEIFM_00221 9.03e-188 - - - S - - - Phage Mu protein F like protein
KBFHEIFM_00223 9.71e-126 yqbD - - L - - - Putative phage serine protease XkdF
KBFHEIFM_00224 1.1e-191 xkdG - - S - - - Phage capsid family
KBFHEIFM_00225 1.19e-30 - - - S - - - YqbF, hypothetical protein domain
KBFHEIFM_00226 1.88e-60 - - - S - - - Protein of unknown function (DUF3199)
KBFHEIFM_00227 2.78e-73 yqbH - - S - - - Domain of unknown function (DUF3599)
KBFHEIFM_00228 1.65e-110 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
KBFHEIFM_00229 3.63e-90 yqbJ - - - - - - -
KBFHEIFM_00230 6.01e-33 - - - - - - - -
KBFHEIFM_00231 2.91e-311 xkdK - - S - - - Phage tail sheath C-terminal domain
KBFHEIFM_00232 6.75e-96 xkdM - - S - - - Phage tail tube protein
KBFHEIFM_00233 3.71e-87 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
KBFHEIFM_00234 0.0 xkdO - - L - - - Transglycosylase SLT domain
KBFHEIFM_00235 9.05e-152 xkdP - - S - - - Lysin motif
KBFHEIFM_00236 3.33e-56 ebrA - - U ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
KBFHEIFM_00237 1.09e-226 xkdQ - - G - - - NLP P60 protein
KBFHEIFM_00238 5.75e-42 xkdR - - S - - - Protein of unknown function (DUF2577)
KBFHEIFM_00239 3.02e-87 xkdS - - S - - - Protein of unknown function (DUF2634)
KBFHEIFM_00240 1.75e-234 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
KBFHEIFM_00241 1.65e-127 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
KBFHEIFM_00242 6.32e-47 - - - - - - - -
KBFHEIFM_00243 4.39e-225 - - - - - - - -
KBFHEIFM_00244 3.15e-58 xkdW - - S - - - XkdW protein
KBFHEIFM_00245 8.43e-27 - - - - - - - -
KBFHEIFM_00246 6.51e-193 xepA - - - - - - -
KBFHEIFM_00247 2.42e-36 xhlA - - S - - - Haemolysin XhlA
KBFHEIFM_00248 8.15e-44 xhlB - - S - - - SPP1 phage holin
KBFHEIFM_00249 1.87e-156 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
KBFHEIFM_00250 1.38e-73 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
KBFHEIFM_00251 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
KBFHEIFM_00252 4.87e-244 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
KBFHEIFM_00254 4.52e-19 - - - - - - - -
KBFHEIFM_00256 1.75e-10 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KBFHEIFM_00263 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
KBFHEIFM_00264 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
KBFHEIFM_00265 2.13e-08 - - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
KBFHEIFM_00266 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
KBFHEIFM_00268 5.36e-203 ybaS - - S - - - Na -dependent transporter
KBFHEIFM_00269 1.24e-178 ybbA - - S ko:K07017 - ko00000 Putative esterase
KBFHEIFM_00270 8.27e-227 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KBFHEIFM_00271 1.17e-225 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KBFHEIFM_00272 1.26e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
KBFHEIFM_00273 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
KBFHEIFM_00274 6.97e-304 ybbC - - S - - - protein conserved in bacteria
KBFHEIFM_00275 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
KBFHEIFM_00276 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
KBFHEIFM_00277 7.29e-304 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KBFHEIFM_00278 1.1e-193 ybbH - - K - - - transcriptional
KBFHEIFM_00279 5.5e-209 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KBFHEIFM_00280 3.13e-114 ybbJ - - J - - - acetyltransferase
KBFHEIFM_00281 4.19e-101 ybbK - - S - - - Protein of unknown function (DUF523)
KBFHEIFM_00287 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KBFHEIFM_00288 2.73e-152 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
KBFHEIFM_00289 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KBFHEIFM_00290 3.55e-291 ybbR - - S - - - protein conserved in bacteria
KBFHEIFM_00291 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KBFHEIFM_00292 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KBFHEIFM_00293 6.55e-221 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KBFHEIFM_00294 6.2e-155 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
KBFHEIFM_00295 7.45e-129 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KBFHEIFM_00296 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
KBFHEIFM_00297 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
KBFHEIFM_00298 2.23e-119 ybcF - - P - - - carbonic anhydrase
KBFHEIFM_00299 4.6e-63 - - - - - - - -
KBFHEIFM_00300 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
KBFHEIFM_00302 9.45e-67 - - - K - - - Helix-turn-helix domain
KBFHEIFM_00303 7.69e-257 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
KBFHEIFM_00305 7.24e-304 - - - J - - - 4Fe-4S single cluster domain
KBFHEIFM_00306 0.0 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
KBFHEIFM_00307 4.48e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KBFHEIFM_00308 1.1e-310 skfF - - S - - - ABC transporter
KBFHEIFM_00309 3.88e-118 - - - C - - - HEAT repeats
KBFHEIFM_00310 5.88e-103 - - - CO - - - Thioredoxin-like domain
KBFHEIFM_00311 8.07e-233 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KBFHEIFM_00312 2.93e-159 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
KBFHEIFM_00313 4.12e-221 - - - T - - - His Kinase A (phospho-acceptor) domain
KBFHEIFM_00315 5.03e-181 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
KBFHEIFM_00316 1.56e-194 ybdN - - - - - - -
KBFHEIFM_00317 1.97e-277 ybdO - - S - - - Domain of unknown function (DUF4885)
KBFHEIFM_00318 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
KBFHEIFM_00319 5.46e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
KBFHEIFM_00320 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
KBFHEIFM_00321 3.02e-45 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
KBFHEIFM_00322 1.76e-102 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
KBFHEIFM_00323 1.09e-313 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
KBFHEIFM_00324 1.11e-54 ybyB - - - - - - -
KBFHEIFM_00325 0.0 ybeC - - E - - - amino acid
KBFHEIFM_00326 8.52e-212 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
KBFHEIFM_00327 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
KBFHEIFM_00328 1.02e-46 - - - S - - - Protein of unknown function (DUF2651)
KBFHEIFM_00329 7.04e-217 ybfA - - K - - - FR47-like protein
KBFHEIFM_00330 1.59e-285 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
KBFHEIFM_00332 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
KBFHEIFM_00333 2.13e-204 ybfH - - EG - - - EamA-like transporter family
KBFHEIFM_00334 1.74e-186 ybfI - - K - - - AraC-like ligand binding domain
KBFHEIFM_00335 2.18e-269 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KBFHEIFM_00336 5.04e-230 mpr - - M - - - Belongs to the peptidase S1B family
KBFHEIFM_00338 1.78e-210 - - - S - - - Alpha/beta hydrolase family
KBFHEIFM_00339 1.15e-122 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KBFHEIFM_00340 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
KBFHEIFM_00341 8.38e-188 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
KBFHEIFM_00342 3.88e-60 ybfN - - - - - - -
KBFHEIFM_00343 0.0 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
KBFHEIFM_00344 5.14e-214 ybfP - - K ko:K13653 - ko00000,ko03000 Transcriptional regulator
KBFHEIFM_00345 2.35e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
KBFHEIFM_00346 6.04e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KBFHEIFM_00347 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KBFHEIFM_00348 3.15e-176 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KBFHEIFM_00349 1.18e-164 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
KBFHEIFM_00351 3.08e-259 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
KBFHEIFM_00352 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
KBFHEIFM_00353 8.72e-232 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
KBFHEIFM_00354 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
KBFHEIFM_00355 2.16e-238 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
KBFHEIFM_00356 4.83e-292 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KBFHEIFM_00357 7.01e-217 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
KBFHEIFM_00358 1.18e-221 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
KBFHEIFM_00359 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KBFHEIFM_00360 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KBFHEIFM_00361 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
KBFHEIFM_00362 2.3e-161 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
KBFHEIFM_00363 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
KBFHEIFM_00364 4.99e-222 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
KBFHEIFM_00365 1.24e-32 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
KBFHEIFM_00366 1.35e-213 eamA1 - - EG - - - spore germination
KBFHEIFM_00367 2.24e-161 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KBFHEIFM_00368 3.08e-214 ycbM - - T - - - Histidine kinase
KBFHEIFM_00369 6.75e-216 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KBFHEIFM_00370 4.25e-150 - - - S - - - ABC-2 family transporter protein
KBFHEIFM_00371 2.21e-76 ycbP - - S - - - Protein of unknown function (DUF2512)
KBFHEIFM_00372 1.82e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
KBFHEIFM_00373 1.56e-173 ycbR - - T - - - vWA found in TerF C terminus
KBFHEIFM_00374 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
KBFHEIFM_00375 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KBFHEIFM_00376 7.6e-160 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KBFHEIFM_00377 2.52e-156 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KBFHEIFM_00378 3.48e-268 ycbU - - E - - - Selenocysteine lyase
KBFHEIFM_00379 2.87e-308 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
KBFHEIFM_00380 4.42e-130 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
KBFHEIFM_00381 6.87e-257 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KBFHEIFM_00382 1.63e-146 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
KBFHEIFM_00383 1.24e-77 - - - S - - - RDD family
KBFHEIFM_00384 5.86e-254 yccF - - K ko:K07039 - ko00000 SEC-C motif
KBFHEIFM_00385 2.51e-212 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
KBFHEIFM_00386 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
KBFHEIFM_00387 2.2e-170 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
KBFHEIFM_00388 7.66e-255 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
KBFHEIFM_00389 9.67e-222 yccK - - C - - - Aldo keto reductase
KBFHEIFM_00390 1.35e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
KBFHEIFM_00391 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KBFHEIFM_00392 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KBFHEIFM_00393 2.27e-124 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
KBFHEIFM_00394 2.86e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
KBFHEIFM_00395 1.96e-179 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
KBFHEIFM_00396 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
KBFHEIFM_00397 2.27e-220 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
KBFHEIFM_00398 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KBFHEIFM_00399 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KBFHEIFM_00400 2.07e-238 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KBFHEIFM_00401 3.75e-141 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
KBFHEIFM_00402 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
KBFHEIFM_00403 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
KBFHEIFM_00404 1.18e-175 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
KBFHEIFM_00405 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
KBFHEIFM_00406 2.96e-245 yceH - - P - - - Belongs to the TelA family
KBFHEIFM_00407 7.75e-278 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
KBFHEIFM_00408 1.07e-263 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
KBFHEIFM_00409 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
KBFHEIFM_00410 1.05e-291 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
KBFHEIFM_00411 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
KBFHEIFM_00412 2.01e-210 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
KBFHEIFM_00413 1.97e-276 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
KBFHEIFM_00414 0.0 ycgA - - S - - - Membrane
KBFHEIFM_00415 2.72e-105 ycgB - - - - - - -
KBFHEIFM_00416 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
KBFHEIFM_00417 1.69e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
KBFHEIFM_00418 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
KBFHEIFM_00419 0.0 mdr - - EGP - - - the major facilitator superfamily
KBFHEIFM_00420 3.7e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
KBFHEIFM_00421 6.42e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
KBFHEIFM_00422 1.85e-195 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
KBFHEIFM_00423 0.0 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
KBFHEIFM_00424 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
KBFHEIFM_00425 5.24e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KBFHEIFM_00426 7.28e-138 tmrB - - S - - - AAA domain
KBFHEIFM_00427 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KBFHEIFM_00428 2.06e-183 - - - Q - - - ubiE/COQ5 methyltransferase family
KBFHEIFM_00429 2.39e-229 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
KBFHEIFM_00430 2.7e-232 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
KBFHEIFM_00431 2.6e-185 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
KBFHEIFM_00432 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
KBFHEIFM_00433 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
KBFHEIFM_00434 2.64e-316 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KBFHEIFM_00435 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
KBFHEIFM_00436 3.82e-195 ycgQ - - S ko:K08986 - ko00000 membrane
KBFHEIFM_00437 2.41e-184 ycgR - - S ko:K07089 - ko00000 permeases
KBFHEIFM_00438 6.94e-202 ycgS - - I - - - alpha/beta hydrolase fold
KBFHEIFM_00439 2.45e-244 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
KBFHEIFM_00440 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
KBFHEIFM_00441 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
KBFHEIFM_00442 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KBFHEIFM_00443 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KBFHEIFM_00444 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
KBFHEIFM_00445 2.24e-282 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
KBFHEIFM_00446 4.38e-24 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
KBFHEIFM_00447 7.52e-144 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
KBFHEIFM_00448 1.16e-128 - - - M - - - ErfK YbiS YcfS YnhG
KBFHEIFM_00449 1.6e-289 yciC - - S - - - GTPases (G3E family)
KBFHEIFM_00450 2.99e-149 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
KBFHEIFM_00451 3.76e-187 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
KBFHEIFM_00452 1.01e-68 yckD - - S - - - Protein of unknown function (DUF2680)
KBFHEIFM_00453 1.29e-58 - - - K - - - MarR family
KBFHEIFM_00454 9e-32 - - - - - - - -
KBFHEIFM_00455 9.38e-07 cysA1 - - S - - - AAA domain
KBFHEIFM_00456 1.04e-123 - - - S - - - AAA domain
KBFHEIFM_00457 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KBFHEIFM_00458 3.36e-91 nin - - S - - - Competence protein J (ComJ)
KBFHEIFM_00459 2.66e-98 nucA - - M - - - Deoxyribonuclease NucA/NucB
KBFHEIFM_00460 5.32e-268 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KBFHEIFM_00461 7.96e-127 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
KBFHEIFM_00462 9.74e-138 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
KBFHEIFM_00463 6.05e-86 hxlR - - K - - - transcriptional
KBFHEIFM_00464 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KBFHEIFM_00465 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KBFHEIFM_00466 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
KBFHEIFM_00467 4.68e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
KBFHEIFM_00468 6.53e-290 - - - EGP - - - Major Facilitator Superfamily
KBFHEIFM_00469 1.88e-125 - - - S - - - YcxB-like protein
KBFHEIFM_00470 8.03e-206 ycxC - - EG - - - EamA-like transporter family
KBFHEIFM_00471 0.0 ycxD - - K - - - GntR family transcriptional regulator
KBFHEIFM_00472 4.76e-145 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
KBFHEIFM_00473 8.71e-148 yczE - - S ko:K07149 - ko00000 membrane
KBFHEIFM_00474 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
KBFHEIFM_00475 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
KBFHEIFM_00476 1.44e-186 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
KBFHEIFM_00477 5.32e-209 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
KBFHEIFM_00478 2.24e-140 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
KBFHEIFM_00479 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
KBFHEIFM_00480 9.86e-53 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
KBFHEIFM_00481 6.65e-104 yclD - - - - - - -
KBFHEIFM_00482 1.45e-197 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
KBFHEIFM_00483 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
KBFHEIFM_00484 0.0 yclG - - M - - - Pectate lyase superfamily protein
KBFHEIFM_00486 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
KBFHEIFM_00487 2.79e-295 gerKC - - S ko:K06297 - ko00000 spore germination
KBFHEIFM_00488 3.8e-253 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
KBFHEIFM_00489 6.85e-155 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
KBFHEIFM_00490 1.05e-273 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
KBFHEIFM_00491 6.39e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KBFHEIFM_00492 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
KBFHEIFM_00493 2.18e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
KBFHEIFM_00495 1.58e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
KBFHEIFM_00497 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
KBFHEIFM_00498 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KBFHEIFM_00499 3.85e-210 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KBFHEIFM_00500 5.63e-176 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KBFHEIFM_00501 1.91e-211 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
KBFHEIFM_00502 0.0 ycnB - - EGP - - - the major facilitator superfamily
KBFHEIFM_00503 2.91e-198 ycnC - - K - - - Transcriptional regulator
KBFHEIFM_00504 2.48e-173 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
KBFHEIFM_00505 1.68e-60 ycnE - - S - - - Monooxygenase
KBFHEIFM_00506 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
KBFHEIFM_00507 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KBFHEIFM_00508 6.58e-311 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KBFHEIFM_00509 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KBFHEIFM_00510 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
KBFHEIFM_00511 3.82e-183 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KBFHEIFM_00512 3.99e-134 ycnI - - S - - - protein conserved in bacteria
KBFHEIFM_00513 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
KBFHEIFM_00514 1.22e-137 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
KBFHEIFM_00515 1.34e-74 - - - - - - - -
KBFHEIFM_00516 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
KBFHEIFM_00517 8.3e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
KBFHEIFM_00518 4.4e-268 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
KBFHEIFM_00519 4.82e-255 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
KBFHEIFM_00520 3.78e-126 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KBFHEIFM_00521 1.92e-140 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
KBFHEIFM_00522 7.69e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
KBFHEIFM_00524 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
KBFHEIFM_00525 4.46e-180 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
KBFHEIFM_00526 1.32e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
KBFHEIFM_00527 1.65e-188 ycsI - - S - - - Belongs to the D-glutamate cyclase family
KBFHEIFM_00528 5.04e-173 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
KBFHEIFM_00529 2.33e-237 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
KBFHEIFM_00530 1.55e-170 kipR - - K - - - Transcriptional regulator
KBFHEIFM_00531 5.94e-154 ycsK - - E - - - anatomical structure formation involved in morphogenesis
KBFHEIFM_00533 7.67e-66 yczJ - - S - - - biosynthesis
KBFHEIFM_00534 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
KBFHEIFM_00535 1.73e-219 ycsN - - S - - - Oxidoreductase
KBFHEIFM_00536 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
KBFHEIFM_00537 0.0 ydaB - - IQ - - - acyl-CoA ligase
KBFHEIFM_00538 3.36e-126 ydaC - - Q - - - Methyltransferase domain
KBFHEIFM_00539 3.74e-207 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KBFHEIFM_00540 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
KBFHEIFM_00541 1.82e-131 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KBFHEIFM_00542 5.24e-101 ydaG - - S - - - general stress protein
KBFHEIFM_00543 1.31e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
KBFHEIFM_00544 3.12e-61 ydzA - - EGP - - - Domain of unknown function (DUF3817)
KBFHEIFM_00545 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
KBFHEIFM_00546 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KBFHEIFM_00547 5.97e-265 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
KBFHEIFM_00548 6.34e-193 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
KBFHEIFM_00549 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
KBFHEIFM_00550 1.93e-304 ydaM - - M - - - Glycosyl transferase family group 2
KBFHEIFM_00551 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
KBFHEIFM_00552 0.0 ydaO - - E - - - amino acid
KBFHEIFM_00553 4.21e-100 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
KBFHEIFM_00554 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
KBFHEIFM_00555 2.5e-52 - - - - - - - -
KBFHEIFM_00556 7.87e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
KBFHEIFM_00557 1.67e-42 ydaS - - S - - - membrane
KBFHEIFM_00558 2.25e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
KBFHEIFM_00559 4.3e-190 ydbA - - P - - - EcsC protein family
KBFHEIFM_00560 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
KBFHEIFM_00561 6.37e-46 ydbB - - G - - - Cupin domain
KBFHEIFM_00562 4.45e-83 ydbC - - S - - - Domain of unknown function (DUF4937
KBFHEIFM_00563 9.11e-197 ydbD - - P ko:K07217 - ko00000 Catalase
KBFHEIFM_00564 7.39e-253 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
KBFHEIFM_00565 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
KBFHEIFM_00566 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
KBFHEIFM_00567 8.93e-290 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KBFHEIFM_00568 1.32e-230 ydbI - - S - - - AI-2E family transporter
KBFHEIFM_00569 2.28e-219 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KBFHEIFM_00570 2.99e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KBFHEIFM_00571 9.32e-70 ydbL - - - - - - -
KBFHEIFM_00572 4.31e-279 ydbM - - I - - - acyl-CoA dehydrogenase
KBFHEIFM_00573 1.14e-26 - - - S - - - Fur-regulated basic protein B
KBFHEIFM_00575 2.72e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KBFHEIFM_00576 4.19e-75 ydbP - - CO - - - Thioredoxin
KBFHEIFM_00577 3.58e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
KBFHEIFM_00578 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KBFHEIFM_00579 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KBFHEIFM_00580 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
KBFHEIFM_00581 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
KBFHEIFM_00582 2e-136 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
KBFHEIFM_00583 3.78e-76 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KBFHEIFM_00584 1.9e-233 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
KBFHEIFM_00585 1.77e-282 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KBFHEIFM_00586 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
KBFHEIFM_00587 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
KBFHEIFM_00588 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
KBFHEIFM_00589 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
KBFHEIFM_00590 2.45e-89 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
KBFHEIFM_00591 1.31e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
KBFHEIFM_00592 1.62e-69 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
KBFHEIFM_00593 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
KBFHEIFM_00594 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KBFHEIFM_00595 1.86e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
KBFHEIFM_00596 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
KBFHEIFM_00597 1.59e-109 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
KBFHEIFM_00605 3.16e-63 ydcL - - L - - - Belongs to the 'phage' integrase family
KBFHEIFM_00608 1.33e-189 - - - S - - - Serine aminopeptidase, S33
KBFHEIFM_00610 1.54e-46 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
KBFHEIFM_00611 2.98e-53 - - - - - - - -
KBFHEIFM_00615 3.35e-143 ydeA - - S - - - DJ-1/PfpI family
KBFHEIFM_00616 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
KBFHEIFM_00617 5.92e-102 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
KBFHEIFM_00618 2.79e-181 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KBFHEIFM_00619 1.47e-211 - - - K - - - AraC-like ligand binding domain
KBFHEIFM_00620 3.23e-220 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KBFHEIFM_00621 8.83e-208 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
KBFHEIFM_00622 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KBFHEIFM_00623 1.27e-275 ydeG - - EGP - - - Major facilitator superfamily
KBFHEIFM_00624 3.21e-70 ydeH - - - - - - -
KBFHEIFM_00625 2.63e-31 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
KBFHEIFM_00626 7.74e-51 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
KBFHEIFM_00627 4.78e-139 - - - - - - - -
KBFHEIFM_00628 2.4e-41 - - - S - - - SNARE associated Golgi protein
KBFHEIFM_00629 1.64e-19 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
KBFHEIFM_00630 2.44e-110 - - - K - - - Transcriptional regulator C-terminal region
KBFHEIFM_00631 1.05e-193 ydeK - - EG - - - -transporter
KBFHEIFM_00632 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KBFHEIFM_00633 1.23e-95 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
KBFHEIFM_00634 1.87e-132 - - - S ko:K07002 - ko00000 Serine hydrolase
KBFHEIFM_00635 1.75e-73 - - - K - - - HxlR-like helix-turn-helix
KBFHEIFM_00636 6.56e-194 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KBFHEIFM_00637 5.03e-91 ydeP - - K - - - Transcriptional regulator
KBFHEIFM_00638 6.98e-142 ywrO - - S ko:K11748 - ko00000,ko02000 NADPH-quinone reductase (modulator of drug activity B)
KBFHEIFM_00639 1.32e-255 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
KBFHEIFM_00640 1.78e-134 ydeS - - K - - - Transcriptional regulator
KBFHEIFM_00641 6.06e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
KBFHEIFM_00642 1.06e-295 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KBFHEIFM_00643 9.03e-188 - - - J - - - GNAT acetyltransferase
KBFHEIFM_00644 8.37e-205 - - - EG - - - EamA-like transporter family
KBFHEIFM_00645 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KBFHEIFM_00646 2.84e-149 ydfE - - S - - - Flavin reductase like domain
KBFHEIFM_00647 5.24e-159 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
KBFHEIFM_00648 1.12e-103 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KBFHEIFM_00650 7.24e-247 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KBFHEIFM_00651 3.82e-141 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KBFHEIFM_00652 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
KBFHEIFM_00653 3.8e-223 - - - S - - - Alpha/beta hydrolase family
KBFHEIFM_00654 6.51e-150 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
KBFHEIFM_00655 1.23e-188 - - - K - - - Bacterial transcription activator, effector binding domain
KBFHEIFM_00656 5.22e-199 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KBFHEIFM_00657 4.7e-143 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
KBFHEIFM_00658 9.49e-239 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
KBFHEIFM_00659 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
KBFHEIFM_00660 3.11e-73 ydfQ - - CO - - - Thioredoxin
KBFHEIFM_00661 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
KBFHEIFM_00662 5.33e-39 - - - - - - - -
KBFHEIFM_00664 6.08e-153 ydfR - - S - - - Protein of unknown function (DUF421)
KBFHEIFM_00665 1.05e-158 ydfS - - S - - - Protein of unknown function (DUF421)
KBFHEIFM_00666 8.99e-99 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
KBFHEIFM_00667 2.74e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
KBFHEIFM_00668 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
KBFHEIFM_00669 1.51e-121 ydgC - - K - - - Bacterial regulatory proteins, tetR family
KBFHEIFM_00670 5.53e-68 - - - S - - - DoxX-like family
KBFHEIFM_00671 4.66e-110 yycN - - K - - - Acetyltransferase
KBFHEIFM_00672 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
KBFHEIFM_00673 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
KBFHEIFM_00674 4.18e-118 - - - S - - - DinB family
KBFHEIFM_00675 1.19e-103 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
KBFHEIFM_00676 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
KBFHEIFM_00677 1.84e-146 ydgI - - C - - - nitroreductase
KBFHEIFM_00678 3.29e-90 - - - K - - - Winged helix DNA-binding domain
KBFHEIFM_00679 2.33e-264 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
KBFHEIFM_00680 2.51e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
KBFHEIFM_00681 5.24e-158 ydhC - - K - - - FCD
KBFHEIFM_00682 1.46e-299 ydhD - - M - - - Glycosyl hydrolase
KBFHEIFM_00683 9.61e-290 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KBFHEIFM_00684 1.43e-161 - - - - - - - -
KBFHEIFM_00685 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
KBFHEIFM_00686 4.73e-89 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
KBFHEIFM_00688 8.94e-107 - - - K - - - Acetyltransferase (GNAT) domain
KBFHEIFM_00689 3.15e-230 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
KBFHEIFM_00690 7.76e-128 ydhK - - M - - - Protein of unknown function (DUF1541)
KBFHEIFM_00691 6.3e-255 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
KBFHEIFM_00692 1.09e-62 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KBFHEIFM_00693 4.82e-67 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KBFHEIFM_00694 4.58e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KBFHEIFM_00695 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KBFHEIFM_00696 7.75e-171 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
KBFHEIFM_00697 1.36e-211 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
KBFHEIFM_00698 2.32e-236 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
KBFHEIFM_00699 2.64e-268 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
KBFHEIFM_00700 4.02e-201 ydhU - - P ko:K07217 - ko00000 Catalase
KBFHEIFM_00703 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
KBFHEIFM_00706 2.22e-230 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KBFHEIFM_00707 1.82e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
KBFHEIFM_00708 1.76e-163 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
KBFHEIFM_00709 2.84e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KBFHEIFM_00710 7.76e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KBFHEIFM_00711 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
KBFHEIFM_00712 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
KBFHEIFM_00713 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KBFHEIFM_00714 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KBFHEIFM_00715 3.55e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KBFHEIFM_00716 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
KBFHEIFM_00717 1.22e-166 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
KBFHEIFM_00718 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KBFHEIFM_00719 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KBFHEIFM_00720 2.57e-191 ydjC - - S - - - Abhydrolase domain containing 18
KBFHEIFM_00721 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
KBFHEIFM_00722 5.88e-256 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
KBFHEIFM_00723 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
KBFHEIFM_00724 1.42e-219 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
KBFHEIFM_00725 9.24e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
KBFHEIFM_00726 1.48e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KBFHEIFM_00727 6.57e-176 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
KBFHEIFM_00728 3.61e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
KBFHEIFM_00729 1.95e-248 - - - S - - - Ion transport 2 domain protein
KBFHEIFM_00730 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KBFHEIFM_00731 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
KBFHEIFM_00732 1.79e-84 ydjM - - M - - - Lytic transglycolase
KBFHEIFM_00733 1.14e-207 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
KBFHEIFM_00735 9.99e-48 ydjO - - S - - - Cold-inducible protein YdjO
KBFHEIFM_00736 7.25e-202 - - - I - - - Alpha/beta hydrolase family
KBFHEIFM_00737 1.44e-228 yeaA - - S - - - Protein of unknown function (DUF4003)
KBFHEIFM_00738 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
KBFHEIFM_00739 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
KBFHEIFM_00740 1.76e-198 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KBFHEIFM_00741 2.79e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
KBFHEIFM_00742 3.74e-284 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
KBFHEIFM_00743 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
KBFHEIFM_00744 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
KBFHEIFM_00745 7.4e-49 - - - - - - - -
KBFHEIFM_00746 1.68e-115 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KBFHEIFM_00747 0.0 - - - S - - - Domain of unknown function (DUF4179)
KBFHEIFM_00748 1.7e-283 pbuG - - S ko:K06901 - ko00000,ko02000 permease
KBFHEIFM_00749 1.95e-163 yebC - - M - - - Membrane
KBFHEIFM_00751 2.66e-120 yebE - - S - - - UPF0316 protein
KBFHEIFM_00752 3.13e-38 yebG - - S - - - NETI protein
KBFHEIFM_00753 9.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KBFHEIFM_00754 2.79e-273 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KBFHEIFM_00755 6.85e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KBFHEIFM_00756 5.86e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
KBFHEIFM_00757 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KBFHEIFM_00758 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KBFHEIFM_00759 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KBFHEIFM_00760 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KBFHEIFM_00761 1.71e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
KBFHEIFM_00762 8.88e-138 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KBFHEIFM_00763 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
KBFHEIFM_00764 4.67e-297 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
KBFHEIFM_00765 1.06e-95 - - - K - - - helix_turn_helix ASNC type
KBFHEIFM_00766 2.9e-292 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
KBFHEIFM_00767 9.89e-37 - - - S - - - Protein of unknown function (DUF2892)
KBFHEIFM_00768 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
KBFHEIFM_00769 2.35e-244 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
KBFHEIFM_00770 7.62e-68 yerC - - S - - - protein conserved in bacteria
KBFHEIFM_00771 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
KBFHEIFM_00773 1.1e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KBFHEIFM_00774 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
KBFHEIFM_00775 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KBFHEIFM_00776 1.77e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
KBFHEIFM_00777 2.02e-249 yerI - - S - - - homoserine kinase type II (protein kinase fold)
KBFHEIFM_00778 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
KBFHEIFM_00779 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KBFHEIFM_00780 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KBFHEIFM_00781 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KBFHEIFM_00782 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KBFHEIFM_00783 4.5e-185 yerO - - K - - - Transcriptional regulator
KBFHEIFM_00784 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KBFHEIFM_00785 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KBFHEIFM_00786 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KBFHEIFM_00787 1.12e-100 - - - K - - - Helix-turn-helix
KBFHEIFM_00788 5.73e-316 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system
KBFHEIFM_00789 2.57e-106 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 DNA specificity domain
KBFHEIFM_00790 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
KBFHEIFM_00791 3.44e-38 - - - S - - - Transcriptional Coactivator p15 (PC4)
KBFHEIFM_00793 2.34e-42 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
KBFHEIFM_00794 1.5e-70 - - - S - - - Tetratricopeptide repeat
KBFHEIFM_00795 9.5e-06 - - - - - - - -
KBFHEIFM_00796 5.45e-23 - - - - - - - -
KBFHEIFM_00797 2.38e-199 - - - S - - - Bacterial EndoU nuclease
KBFHEIFM_00799 1.62e-125 - - - L - - - endonuclease activity
KBFHEIFM_00800 3.42e-16 - - - S - - - Lysozyme inhibitor LprI
KBFHEIFM_00801 4.93e-82 - - - S - - - membrane
KBFHEIFM_00802 3e-272 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
KBFHEIFM_00804 6.29e-162 yeeN - - K - - - transcriptional regulatory protein
KBFHEIFM_00806 2.44e-130 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
KBFHEIFM_00807 2.02e-106 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
KBFHEIFM_00808 9.46e-201 yesF - - GM - - - NAD(P)H-binding
KBFHEIFM_00809 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
KBFHEIFM_00810 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
KBFHEIFM_00811 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
KBFHEIFM_00812 1.76e-132 yesJ - - K - - - Acetyltransferase (GNAT) family
KBFHEIFM_00814 3.52e-135 yesL - - S - - - Protein of unknown function, DUF624
KBFHEIFM_00815 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KBFHEIFM_00816 5.07e-260 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
KBFHEIFM_00817 5.06e-315 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KBFHEIFM_00818 3.35e-217 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KBFHEIFM_00819 2.08e-209 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KBFHEIFM_00820 1.88e-252 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
KBFHEIFM_00821 0.0 yesS - - K - - - Transcriptional regulator
KBFHEIFM_00822 2.22e-165 - - - E - - - GDSL-like Lipase/Acylhydrolase
KBFHEIFM_00823 7.22e-163 yesU - - S - - - Domain of unknown function (DUF1961)
KBFHEIFM_00824 7.78e-143 - - - S - - - Protein of unknown function, DUF624
KBFHEIFM_00825 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
KBFHEIFM_00826 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
KBFHEIFM_00827 7.51e-159 - - - E - - - GDSL-like Lipase/Acylhydrolase
KBFHEIFM_00828 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
KBFHEIFM_00829 0.0 yetA - - - - - - -
KBFHEIFM_00830 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KBFHEIFM_00831 1.13e-224 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
KBFHEIFM_00832 7.52e-207 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KBFHEIFM_00833 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
KBFHEIFM_00834 3.66e-157 yetF - - S - - - membrane
KBFHEIFM_00835 4.67e-73 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
KBFHEIFM_00836 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KBFHEIFM_00837 1.75e-44 - - - - - - - -
KBFHEIFM_00838 1.25e-184 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KBFHEIFM_00839 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
KBFHEIFM_00840 4.23e-134 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
KBFHEIFM_00841 2.73e-198 - - - EG - - - EamA-like transporter family
KBFHEIFM_00842 2.64e-114 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
KBFHEIFM_00843 4.9e-263 yetM - - CH - - - FAD binding domain
KBFHEIFM_00844 6.1e-255 yetN - - S - - - Protein of unknown function (DUF3900)
KBFHEIFM_00845 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
KBFHEIFM_00846 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
KBFHEIFM_00847 5.07e-189 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
KBFHEIFM_00848 6.8e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
KBFHEIFM_00849 3.99e-231 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
KBFHEIFM_00850 2.44e-286 yfnE - - S - - - Glycosyltransferase like family 2
KBFHEIFM_00851 3.72e-240 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
KBFHEIFM_00852 5.1e-267 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KBFHEIFM_00853 4.49e-169 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
KBFHEIFM_00854 3.41e-312 yfnA - - E ko:K03294 - ko00000 amino acid
KBFHEIFM_00855 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KBFHEIFM_00856 5.14e-161 yfmS - - NT - - - chemotaxis protein
KBFHEIFM_00857 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KBFHEIFM_00858 6.23e-97 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
KBFHEIFM_00859 4.14e-89 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
KBFHEIFM_00860 7.24e-265 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
KBFHEIFM_00861 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KBFHEIFM_00862 7.25e-264 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
KBFHEIFM_00863 3.58e-76 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
KBFHEIFM_00864 4.71e-239 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
KBFHEIFM_00865 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
KBFHEIFM_00866 2.1e-223 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KBFHEIFM_00867 6.71e-220 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KBFHEIFM_00868 5.57e-219 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
KBFHEIFM_00869 1.06e-31 - - - S - - - Protein of unknown function (DUF3212)
KBFHEIFM_00870 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
KBFHEIFM_00871 4.74e-305 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
KBFHEIFM_00872 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
KBFHEIFM_00873 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
KBFHEIFM_00874 1.88e-152 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
KBFHEIFM_00875 9.38e-229 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
KBFHEIFM_00876 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
KBFHEIFM_00877 5.93e-193 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
KBFHEIFM_00878 1.67e-276 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KBFHEIFM_00879 2.97e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
KBFHEIFM_00880 3.42e-157 yflK - - S - - - protein conserved in bacteria
KBFHEIFM_00881 1.1e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
KBFHEIFM_00882 6.9e-27 yflI - - - - - - -
KBFHEIFM_00883 2.1e-65 yflH - - S - - - Protein of unknown function (DUF3243)
KBFHEIFM_00884 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
KBFHEIFM_00885 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
KBFHEIFM_00886 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
KBFHEIFM_00887 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
KBFHEIFM_00888 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
KBFHEIFM_00889 2.56e-248 yfkT - - E ko:K06309 - ko00000 Spore germination protein
KBFHEIFM_00891 2.28e-271 yfkR - - S ko:K06297,ko:K06308 - ko00000 spore germination
KBFHEIFM_00892 0.0 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
KBFHEIFM_00893 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KBFHEIFM_00894 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
KBFHEIFM_00895 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
KBFHEIFM_00896 6.16e-160 frp - - C - - - nitroreductase
KBFHEIFM_00897 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KBFHEIFM_00898 5.48e-114 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
KBFHEIFM_00899 6.21e-266 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
KBFHEIFM_00900 5.99e-41 yfkK - - S - - - Belongs to the UPF0435 family
KBFHEIFM_00901 8.37e-108 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KBFHEIFM_00902 1.03e-66 yfkI - - S - - - gas vesicle protein
KBFHEIFM_00903 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
KBFHEIFM_00904 1.9e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
KBFHEIFM_00905 1.34e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
KBFHEIFM_00906 3.69e-189 yfkD - - S - - - YfkD-like protein
KBFHEIFM_00907 3.65e-190 yfkC - - M - - - Mechanosensitive ion channel
KBFHEIFM_00908 1.76e-283 yfkA - - S - - - YfkB-like domain
KBFHEIFM_00909 3.26e-36 yfjT - - - - - - -
KBFHEIFM_00910 5.95e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
KBFHEIFM_00911 1.38e-193 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
KBFHEIFM_00912 7.8e-237 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
KBFHEIFM_00913 3.76e-212 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KBFHEIFM_00914 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KBFHEIFM_00915 3.04e-59 - - - S - - - YfzA-like protein
KBFHEIFM_00916 1.65e-241 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KBFHEIFM_00917 1.07e-107 yfjM - - S - - - Psort location Cytoplasmic, score
KBFHEIFM_00920 1.36e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KBFHEIFM_00921 6.2e-241 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KBFHEIFM_00922 6.64e-262 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KBFHEIFM_00923 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KBFHEIFM_00924 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
KBFHEIFM_00925 2.75e-34 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
KBFHEIFM_00926 7.42e-75 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
KBFHEIFM_00927 3.73e-101 - - - S - - - Family of unknown function (DUF5381)
KBFHEIFM_00928 6.08e-131 yfjD - - S - - - Family of unknown function (DUF5381)
KBFHEIFM_00929 2.5e-185 yfjC - - - - - - -
KBFHEIFM_00930 1.94e-270 yfjB - - - - - - -
KBFHEIFM_00931 3.78e-59 yfjA - - S - - - Belongs to the WXG100 family
KBFHEIFM_00932 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KBFHEIFM_00933 6.12e-181 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
KBFHEIFM_00934 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KBFHEIFM_00935 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
KBFHEIFM_00936 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
KBFHEIFM_00937 3.34e-83 yfiD3 - - S - - - DoxX
KBFHEIFM_00938 5.98e-208 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
KBFHEIFM_00940 2.42e-272 baeS - - T - - - Histidine kinase
KBFHEIFM_00941 1.01e-144 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
KBFHEIFM_00942 6.21e-214 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KBFHEIFM_00943 4.37e-266 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
KBFHEIFM_00944 5.69e-261 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
KBFHEIFM_00945 1.89e-128 padR - - K - - - transcriptional
KBFHEIFM_00946 7.87e-128 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
KBFHEIFM_00947 6.57e-253 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KBFHEIFM_00948 9.43e-127 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
KBFHEIFM_00949 0.0 yfiU - - EGP - - - the major facilitator superfamily
KBFHEIFM_00950 1.27e-104 yfiV - - K - - - transcriptional
KBFHEIFM_00951 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KBFHEIFM_00952 1.01e-226 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
KBFHEIFM_00953 1.54e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KBFHEIFM_00954 5.18e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KBFHEIFM_00955 7.61e-215 yfhB - - S - - - PhzF family
KBFHEIFM_00956 2.87e-138 yfhC - - C - - - nitroreductase
KBFHEIFM_00957 8.86e-35 yfhD - - S - - - YfhD-like protein
KBFHEIFM_00959 1.13e-221 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
KBFHEIFM_00960 3.25e-181 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
KBFHEIFM_00961 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
KBFHEIFM_00963 2.45e-268 yfhI - - EGP - - - -transporter
KBFHEIFM_00964 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
KBFHEIFM_00965 8.95e-60 yfhJ - - S - - - WVELL protein
KBFHEIFM_00966 4.18e-118 yfhK - - T - - - Bacterial SH3 domain homologues
KBFHEIFM_00967 3.34e-62 yfhL - - S - - - SdpI/YhfL protein family
KBFHEIFM_00968 1.13e-217 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
KBFHEIFM_00969 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
KBFHEIFM_00970 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
KBFHEIFM_00971 7.22e-237 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
KBFHEIFM_00972 1.99e-266 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
KBFHEIFM_00973 1.73e-48 yfhS - - - - - - -
KBFHEIFM_00974 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KBFHEIFM_00975 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
KBFHEIFM_00976 2.01e-49 ygaB - - S - - - YgaB-like protein
KBFHEIFM_00977 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
KBFHEIFM_00978 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
KBFHEIFM_00979 1.87e-238 ygaE - - S - - - Membrane
KBFHEIFM_00980 3.26e-312 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
KBFHEIFM_00981 1.69e-112 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
KBFHEIFM_00982 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
KBFHEIFM_00983 1.57e-73 ygzB - - S - - - UPF0295 protein
KBFHEIFM_00984 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
KBFHEIFM_00985 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
KBFHEIFM_01002 3.69e-184 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
KBFHEIFM_01003 1.58e-36 - - - - - - - -
KBFHEIFM_01004 1.11e-169 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
KBFHEIFM_01005 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KBFHEIFM_01006 0.0 ygaK - - C - - - Berberine and berberine like
KBFHEIFM_01008 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
KBFHEIFM_01009 2.21e-179 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
KBFHEIFM_01010 8.45e-218 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
KBFHEIFM_01011 4.82e-189 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KBFHEIFM_01012 9.35e-276 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
KBFHEIFM_01014 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KBFHEIFM_01015 2.79e-102 ygaO - - - - - - -
KBFHEIFM_01016 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
KBFHEIFM_01018 1.92e-147 yhzB - - S - - - B3/4 domain
KBFHEIFM_01019 3.44e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KBFHEIFM_01020 2.55e-221 yhbB - - S - - - Putative amidase domain
KBFHEIFM_01021 1.08e-111 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KBFHEIFM_01022 9.75e-143 yhbD - - K - - - Protein of unknown function (DUF4004)
KBFHEIFM_01023 1.32e-95 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
KBFHEIFM_01024 4.06e-103 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
KBFHEIFM_01025 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
KBFHEIFM_01026 9.92e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
KBFHEIFM_01027 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
KBFHEIFM_01028 3.8e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
KBFHEIFM_01029 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
KBFHEIFM_01030 4.87e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
KBFHEIFM_01031 9.3e-58 yhcC - - - - - - -
KBFHEIFM_01032 1.03e-69 - - - - - - - -
KBFHEIFM_01033 4.78e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
KBFHEIFM_01034 3.24e-156 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KBFHEIFM_01035 1.85e-212 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KBFHEIFM_01036 5.71e-211 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KBFHEIFM_01037 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
KBFHEIFM_01038 1.06e-192 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
KBFHEIFM_01039 2.88e-250 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
KBFHEIFM_01040 8.74e-300 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KBFHEIFM_01041 1.13e-70 yhcM - - - - - - -
KBFHEIFM_01042 2.69e-111 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KBFHEIFM_01043 2.29e-226 yhcP - - - - - - -
KBFHEIFM_01044 1.68e-146 yhcQ - - M - - - Spore coat protein
KBFHEIFM_01045 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KBFHEIFM_01046 4.36e-133 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
KBFHEIFM_01047 2.76e-217 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
KBFHEIFM_01048 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
KBFHEIFM_01049 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
KBFHEIFM_01050 2.5e-154 yhcW - - S ko:K07025 - ko00000 hydrolase
KBFHEIFM_01051 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KBFHEIFM_01052 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KBFHEIFM_01053 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KBFHEIFM_01054 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
KBFHEIFM_01055 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KBFHEIFM_01056 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KBFHEIFM_01057 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
KBFHEIFM_01058 4.42e-271 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
KBFHEIFM_01059 9.41e-145 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KBFHEIFM_01060 2.7e-115 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
KBFHEIFM_01061 1.65e-51 yhdB - - S - - - YhdB-like protein
KBFHEIFM_01062 1.02e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
KBFHEIFM_01063 2.79e-274 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
KBFHEIFM_01064 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
KBFHEIFM_01065 4.33e-306 ygxB - - M - - - Conserved TM helix
KBFHEIFM_01066 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
KBFHEIFM_01067 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
KBFHEIFM_01068 7.21e-204 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
KBFHEIFM_01069 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
KBFHEIFM_01070 5.28e-261 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
KBFHEIFM_01071 1.3e-204 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KBFHEIFM_01072 8.94e-317 yhdG - - E ko:K03294 - ko00000 amino acid
KBFHEIFM_01073 4.29e-310 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KBFHEIFM_01074 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KBFHEIFM_01075 1.68e-98 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KBFHEIFM_01076 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
KBFHEIFM_01077 1.44e-256 yhdL - - S - - - Sigma factor regulator N-terminal
KBFHEIFM_01078 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KBFHEIFM_01079 6.74e-244 yhdN - - C - - - Aldo keto reductase
KBFHEIFM_01080 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KBFHEIFM_01081 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
KBFHEIFM_01082 7.39e-98 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
KBFHEIFM_01083 1.03e-283 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
KBFHEIFM_01084 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
KBFHEIFM_01085 1.18e-64 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KBFHEIFM_01086 5.83e-87 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KBFHEIFM_01087 3.68e-172 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
KBFHEIFM_01088 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
KBFHEIFM_01089 1.06e-258 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
KBFHEIFM_01090 1.63e-177 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
KBFHEIFM_01091 5.24e-196 nodB1 - - G - - - deacetylase
KBFHEIFM_01092 3.16e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
KBFHEIFM_01093 2.83e-300 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
KBFHEIFM_01094 1.53e-108 nhaX - - T - - - Belongs to the universal stress protein A family
KBFHEIFM_01095 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
KBFHEIFM_01096 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
KBFHEIFM_01097 3.18e-141 yheG - - GM - - - NAD(P)H-binding
KBFHEIFM_01098 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
KBFHEIFM_01099 6.53e-49 yheE - - S - - - Family of unknown function (DUF5342)
KBFHEIFM_01100 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
KBFHEIFM_01101 3.37e-276 yheC - - HJ - - - YheC/D like ATP-grasp
KBFHEIFM_01102 4.85e-258 yheB - - S - - - Belongs to the UPF0754 family
KBFHEIFM_01103 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
KBFHEIFM_01104 1.06e-260 yhaZ - - L - - - DNA alkylation repair enzyme
KBFHEIFM_01105 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
KBFHEIFM_01106 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
KBFHEIFM_01107 3.74e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
KBFHEIFM_01108 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
KBFHEIFM_01110 5.06e-171 yhaR - - I - - - enoyl-CoA hydratase
KBFHEIFM_01111 2.29e-36 - - - S - - - YhzD-like protein
KBFHEIFM_01112 1.31e-213 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KBFHEIFM_01113 5.99e-271 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
KBFHEIFM_01114 6.11e-297 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
KBFHEIFM_01115 0.0 yhaN - - L - - - AAA domain
KBFHEIFM_01116 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
KBFHEIFM_01117 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
KBFHEIFM_01118 6.57e-179 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KBFHEIFM_01119 4.02e-116 yhaK - - S - - - Putative zincin peptidase
KBFHEIFM_01120 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
KBFHEIFM_01121 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
KBFHEIFM_01122 1.74e-54 yhaH - - S - - - YtxH-like protein
KBFHEIFM_01123 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
KBFHEIFM_01124 2.51e-260 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KBFHEIFM_01125 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KBFHEIFM_01126 1.28e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
KBFHEIFM_01127 5.15e-271 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
KBFHEIFM_01128 1.67e-160 ecsC - - S - - - EcsC protein family
KBFHEIFM_01129 1.27e-290 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KBFHEIFM_01130 1.1e-311 yhfA - - C - - - membrane
KBFHEIFM_01131 1.33e-23 - - - C - - - Rubrerythrin
KBFHEIFM_01132 7.6e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
KBFHEIFM_01133 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KBFHEIFM_01134 2.14e-258 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KBFHEIFM_01135 3.41e-231 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
KBFHEIFM_01136 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KBFHEIFM_01137 5.79e-132 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
KBFHEIFM_01138 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
KBFHEIFM_01139 1.77e-236 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KBFHEIFM_01140 1.88e-177 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
KBFHEIFM_01141 1.55e-252 yhfE - - G - - - peptidase M42
KBFHEIFM_01142 1.53e-93 - - - S - - - ASCH
KBFHEIFM_01143 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KBFHEIFM_01144 1.4e-181 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
KBFHEIFM_01145 4.06e-245 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
KBFHEIFM_01146 2.04e-141 yhfK - - GM - - - NmrA-like family
KBFHEIFM_01147 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
KBFHEIFM_01148 2.78e-85 yhfM - - - - - - -
KBFHEIFM_01149 2.76e-307 yhfN - - O - - - Peptidase M48
KBFHEIFM_01150 1.7e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KBFHEIFM_01151 2.54e-101 - - - K - - - acetyltransferase
KBFHEIFM_01152 2.4e-232 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
KBFHEIFM_01153 7.94e-223 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
KBFHEIFM_01154 1.13e-139 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
KBFHEIFM_01155 8.58e-250 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
KBFHEIFM_01156 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
KBFHEIFM_01157 1.21e-117 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
KBFHEIFM_01158 6.15e-259 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
KBFHEIFM_01159 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
KBFHEIFM_01160 7.82e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KBFHEIFM_01161 9.84e-45 yhzC - - S - - - IDEAL
KBFHEIFM_01162 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
KBFHEIFM_01163 1.21e-214 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
KBFHEIFM_01164 5.64e-54 yhjA - - S - - - Excalibur calcium-binding domain
KBFHEIFM_01165 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KBFHEIFM_01166 9.31e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
KBFHEIFM_01167 2.12e-77 yhjD - - - - - - -
KBFHEIFM_01168 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
KBFHEIFM_01169 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KBFHEIFM_01170 0.0 yhjG - - CH - - - FAD binding domain
KBFHEIFM_01171 7.77e-120 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
KBFHEIFM_01172 2.11e-271 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
KBFHEIFM_01173 4.46e-254 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
KBFHEIFM_01174 3.07e-204 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
KBFHEIFM_01175 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
KBFHEIFM_01176 3.07e-239 yhjM - - K - - - Transcriptional regulator
KBFHEIFM_01177 4.14e-258 yhjN - - S ko:K07120 - ko00000 membrane
KBFHEIFM_01178 1.73e-270 - - - EGP - - - Transmembrane secretion effector
KBFHEIFM_01179 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
KBFHEIFM_01180 9.3e-102 yhjR - - S - - - Rubrerythrin
KBFHEIFM_01181 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
KBFHEIFM_01182 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
KBFHEIFM_01183 2.32e-279 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KBFHEIFM_01184 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
KBFHEIFM_01185 6.4e-65 yisB - - V - - - COG1403 Restriction endonuclease
KBFHEIFM_01186 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
KBFHEIFM_01187 4.08e-88 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
KBFHEIFM_01188 7.36e-34 gerPD - - S ko:K06302 - ko00000 Spore germination protein
KBFHEIFM_01189 2.88e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
KBFHEIFM_01190 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
KBFHEIFM_01191 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
KBFHEIFM_01192 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
KBFHEIFM_01193 2.2e-221 cotH - - M ko:K06330 - ko00000 Spore Coat
KBFHEIFM_01194 7.64e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
KBFHEIFM_01195 1.02e-74 yisL - - S - - - UPF0344 protein
KBFHEIFM_01196 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KBFHEIFM_01197 3.39e-128 yisN - - S - - - Protein of unknown function (DUF2777)
KBFHEIFM_01198 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
KBFHEIFM_01199 1.07e-114 yizA - - S - - - Damage-inducible protein DinB
KBFHEIFM_01200 4.6e-191 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
KBFHEIFM_01201 1.01e-310 yisQ - - V - - - Mate efflux family protein
KBFHEIFM_01202 1.41e-207 yisR - - K - - - Transcriptional regulator
KBFHEIFM_01203 1.06e-234 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KBFHEIFM_01204 9.59e-245 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
KBFHEIFM_01205 5.98e-121 yisT - - S - - - DinB family
KBFHEIFM_01206 1.49e-137 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
KBFHEIFM_01207 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KBFHEIFM_01208 6.86e-73 yisX - - S - - - Pentapeptide repeats (9 copies)
KBFHEIFM_01209 2.25e-199 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KBFHEIFM_01210 1.66e-144 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
KBFHEIFM_01211 3.23e-294 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
KBFHEIFM_01212 1.58e-183 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
KBFHEIFM_01213 1.01e-157 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
KBFHEIFM_01214 1.75e-179 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
KBFHEIFM_01215 6.62e-140 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
KBFHEIFM_01216 4.32e-283 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
KBFHEIFM_01217 1.67e-290 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KBFHEIFM_01218 2.23e-197 yitH - - K - - - Acetyltransferase (GNAT) domain
KBFHEIFM_01219 1.25e-92 - - - S - - - Acetyltransferase (GNAT) domain
KBFHEIFM_01220 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
KBFHEIFM_01221 1.06e-77 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
KBFHEIFM_01222 1.59e-203 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
KBFHEIFM_01223 4.16e-122 - - - - - - - -
KBFHEIFM_01224 1.17e-217 - - - - - - - -
KBFHEIFM_01225 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
KBFHEIFM_01226 1.2e-76 - - - K - - - Transcriptional regulator PadR-like family
KBFHEIFM_01227 5.24e-121 - - - - - - - -
KBFHEIFM_01228 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
KBFHEIFM_01229 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
KBFHEIFM_01230 9.13e-202 yitS - - S - - - protein conserved in bacteria
KBFHEIFM_01231 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KBFHEIFM_01232 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
KBFHEIFM_01233 1.01e-25 - - - S - - - Protein of unknown function (DUF3813)
KBFHEIFM_01234 1.92e-08 - - - - - - - -
KBFHEIFM_01235 1.52e-198 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
KBFHEIFM_01236 1.98e-182 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
KBFHEIFM_01237 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
KBFHEIFM_01238 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
KBFHEIFM_01239 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
KBFHEIFM_01240 3.24e-114 yitZ - - G - - - Major Facilitator Superfamily
KBFHEIFM_01241 9.68e-251 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KBFHEIFM_01242 1.74e-293 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KBFHEIFM_01243 7.35e-175 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
KBFHEIFM_01244 2.8e-277 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
KBFHEIFM_01245 2.33e-262 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
KBFHEIFM_01246 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
KBFHEIFM_01247 4.27e-225 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KBFHEIFM_01248 2.51e-39 yjzC - - S - - - YjzC-like protein
KBFHEIFM_01249 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
KBFHEIFM_01250 1.4e-181 yjaU - - I - - - carboxylic ester hydrolase activity
KBFHEIFM_01251 4.28e-131 yjaV - - - - - - -
KBFHEIFM_01252 3.7e-234 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
KBFHEIFM_01253 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
KBFHEIFM_01254 2.67e-38 yjzB - - - - - - -
KBFHEIFM_01255 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KBFHEIFM_01256 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KBFHEIFM_01257 3.86e-192 yjaZ - - O - - - Zn-dependent protease
KBFHEIFM_01258 4.15e-232 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KBFHEIFM_01259 4.01e-235 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KBFHEIFM_01260 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
KBFHEIFM_01261 6.73e-216 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KBFHEIFM_01262 1.03e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KBFHEIFM_01263 3.18e-190 yjbA - - S - - - Belongs to the UPF0736 family
KBFHEIFM_01264 2.06e-233 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
KBFHEIFM_01265 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
KBFHEIFM_01266 1.03e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KBFHEIFM_01267 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KBFHEIFM_01268 3.92e-249 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KBFHEIFM_01269 4.43e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KBFHEIFM_01270 5.3e-257 yjbB - - EGP - - - Major Facilitator Superfamily
KBFHEIFM_01271 8.88e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KBFHEIFM_01272 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KBFHEIFM_01273 7.1e-144 yjbE - - P - - - Integral membrane protein TerC family
KBFHEIFM_01274 4.65e-149 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KBFHEIFM_01275 8.84e-282 coiA - - S ko:K06198 - ko00000 Competence protein
KBFHEIFM_01276 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
KBFHEIFM_01277 2.68e-28 - - - - - - - -
KBFHEIFM_01279 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
KBFHEIFM_01280 4.97e-93 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
KBFHEIFM_01281 3.42e-127 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KBFHEIFM_01282 7.02e-128 yjbK - - S - - - protein conserved in bacteria
KBFHEIFM_01283 2.18e-80 yjbL - - S - - - Belongs to the UPF0738 family
KBFHEIFM_01284 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
KBFHEIFM_01285 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KBFHEIFM_01286 4.28e-202 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
KBFHEIFM_01287 1.91e-179 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
KBFHEIFM_01288 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KBFHEIFM_01289 5.7e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KBFHEIFM_01290 2.32e-138 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
KBFHEIFM_01291 2.46e-272 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
KBFHEIFM_01292 2.18e-41 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
KBFHEIFM_01293 6.78e-174 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
KBFHEIFM_01294 1.02e-236 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KBFHEIFM_01295 1.97e-190 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
KBFHEIFM_01296 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
KBFHEIFM_01297 6.3e-105 yjbX - - S - - - Spore coat protein
KBFHEIFM_01298 4.76e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
KBFHEIFM_01299 3.12e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
KBFHEIFM_01300 5.34e-98 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
KBFHEIFM_01301 1.66e-38 cotW - - - ko:K06341 - ko00000 -
KBFHEIFM_01302 1.88e-68 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
KBFHEIFM_01303 2.05e-74 yjcA - - S - - - Protein of unknown function (DUF1360)
KBFHEIFM_01306 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
KBFHEIFM_01307 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
KBFHEIFM_01308 2.57e-50 - - - - - - - -
KBFHEIFM_01309 7.75e-94 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KBFHEIFM_01310 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
KBFHEIFM_01311 1.63e-178 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
KBFHEIFM_01312 1.98e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
KBFHEIFM_01313 7.47e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
KBFHEIFM_01314 9.74e-126 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
KBFHEIFM_01315 1.74e-272 yjcL - - S - - - Protein of unknown function (DUF819)
KBFHEIFM_01319 7.57e-269 - - - S - - - Putative amidase domain
KBFHEIFM_01320 4.37e-68 yjcN - - - - - - -
KBFHEIFM_01321 1.04e-48 yqaS - - L - - - DNA packaging
KBFHEIFM_01322 1.27e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
KBFHEIFM_01323 2.81e-180 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
KBFHEIFM_01324 0.000141 - - - - - - - -
KBFHEIFM_01325 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
KBFHEIFM_01326 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KBFHEIFM_01327 8.8e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
KBFHEIFM_01328 3.93e-77 yjdF3 - - S - - - Protein of unknown function (DUF2992)
KBFHEIFM_01329 5.12e-117 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
KBFHEIFM_01331 1.18e-104 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KBFHEIFM_01332 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
KBFHEIFM_01333 2.31e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
KBFHEIFM_01334 2.16e-223 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KBFHEIFM_01336 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
KBFHEIFM_01337 8.68e-106 - - - S - - - Protein of unknown function (DUF2690)
KBFHEIFM_01338 1.13e-29 yjfB - - S - - - Putative motility protein
KBFHEIFM_01339 1.52e-208 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
KBFHEIFM_01340 3.95e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
KBFHEIFM_01341 4.96e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
KBFHEIFM_01342 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
KBFHEIFM_01343 1.6e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
KBFHEIFM_01345 1.06e-146 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
KBFHEIFM_01347 1.11e-284 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
KBFHEIFM_01348 7.18e-279 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KBFHEIFM_01349 3.2e-41 - - - - - - - -
KBFHEIFM_01350 7.14e-188 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
KBFHEIFM_01351 9.04e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
KBFHEIFM_01352 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KBFHEIFM_01353 1.81e-224 yjlA - - EG - - - Putative multidrug resistance efflux transporter
KBFHEIFM_01354 2.46e-118 yjlB - - S - - - Cupin domain
KBFHEIFM_01355 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
KBFHEIFM_01356 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
KBFHEIFM_01357 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
KBFHEIFM_01358 6.16e-314 - - - G ko:K03292 - ko00000 symporter YjmB
KBFHEIFM_01359 3.45e-240 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
KBFHEIFM_01360 6.24e-244 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
KBFHEIFM_01361 1.86e-271 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
KBFHEIFM_01362 5.47e-196 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KBFHEIFM_01363 5.58e-289 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
KBFHEIFM_01364 1.64e-236 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
KBFHEIFM_01365 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
KBFHEIFM_01366 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
KBFHEIFM_01367 1.59e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
KBFHEIFM_01368 2.71e-103 yjoA - - S - - - DinB family
KBFHEIFM_01369 1.43e-312 VCP - - O - - - AAA domain (dynein-related subfamily)
KBFHEIFM_01370 8.59e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
KBFHEIFM_01372 1.47e-54 - - - S - - - YCII-related domain
KBFHEIFM_01373 5.34e-218 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
KBFHEIFM_01374 1.35e-80 yjqA - - S - - - Bacterial PH domain
KBFHEIFM_01375 5.99e-143 yjqB - - S - - - Pfam:DUF867
KBFHEIFM_01376 3.73e-203 yjqC - - P ko:K07217 - ko00000 Catalase
KBFHEIFM_01377 7.3e-143 xkdA - - E - - - IrrE N-terminal-like domain
KBFHEIFM_01378 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
KBFHEIFM_01380 1.78e-201 xkdB - - K - - - sequence-specific DNA binding
KBFHEIFM_01381 5.88e-150 xkdC - - L - - - Bacterial dnaA protein
KBFHEIFM_01386 2.83e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
KBFHEIFM_01387 2.27e-177 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
KBFHEIFM_01388 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
KBFHEIFM_01389 0.0 yqbA - - S - - - portal protein
KBFHEIFM_01390 9.88e-177 xkdF3 - - L - - - Putative phage serine protease XkdF
KBFHEIFM_01391 3.91e-217 xkdG - - S - - - Phage capsid family
KBFHEIFM_01392 3.85e-81 yqbG - - S - - - Protein of unknown function (DUF3199)
KBFHEIFM_01393 5.02e-84 yqbH - - S - - - Domain of unknown function (DUF3599)
KBFHEIFM_01394 1.96e-113 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
KBFHEIFM_01395 9.26e-98 xkdJ - - - - - - -
KBFHEIFM_01396 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
KBFHEIFM_01397 6.01e-99 xkdM - - S - - - Phage tail tube protein
KBFHEIFM_01398 3.21e-99 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
KBFHEIFM_01399 0.0 xkdO - - L - - - Transglycosylase SLT domain
KBFHEIFM_01400 4.87e-156 xkdP - - S - - - Lysin motif
KBFHEIFM_01401 9.42e-232 xkdQ - - G - - - NLP P60 protein
KBFHEIFM_01402 4.32e-53 xkdR - - S - - - Protein of unknown function (DUF2577)
KBFHEIFM_01403 1.97e-92 xkdS - - S - - - Protein of unknown function (DUF2634)
KBFHEIFM_01404 7.59e-245 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
KBFHEIFM_01405 3.23e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
KBFHEIFM_01406 4.43e-56 - - - - - - - -
KBFHEIFM_01407 5.96e-231 - - - - - - - -
KBFHEIFM_01408 5.66e-70 xkdW - - S - - - XkdW protein
KBFHEIFM_01409 2.68e-32 xkdX - - - - - - -
KBFHEIFM_01410 1.1e-193 xepA - - - - - - -
KBFHEIFM_01411 2.21e-51 xhlA - - S - - - Haemolysin XhlA
KBFHEIFM_01412 3.87e-51 xhlB - - S - - - SPP1 phage holin
KBFHEIFM_01413 1.93e-208 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
KBFHEIFM_01414 9.5e-77 - - - G - - - Acyltransferase family
KBFHEIFM_01415 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
KBFHEIFM_01416 1.97e-174 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
KBFHEIFM_01417 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
KBFHEIFM_01418 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
KBFHEIFM_01419 2.57e-309 steT - - E ko:K03294 - ko00000 amino acid
KBFHEIFM_01420 9.82e-234 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
KBFHEIFM_01421 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KBFHEIFM_01422 2.21e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
KBFHEIFM_01424 2.4e-282 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KBFHEIFM_01425 1.58e-176 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
KBFHEIFM_01426 5.7e-196 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
KBFHEIFM_01427 5.61e-203 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KBFHEIFM_01428 3.02e-224 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KBFHEIFM_01429 9.48e-237 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KBFHEIFM_01430 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
KBFHEIFM_01432 8.23e-226 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
KBFHEIFM_01433 5.9e-258 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
KBFHEIFM_01434 4.96e-217 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KBFHEIFM_01435 8.44e-237 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KBFHEIFM_01436 5.69e-261 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
KBFHEIFM_01437 1.78e-205 ykgA - - E - - - Amidinotransferase
KBFHEIFM_01438 1.55e-119 ykhA - - I - - - Acyl-CoA hydrolase
KBFHEIFM_01439 2.18e-288 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KBFHEIFM_01440 7.15e-14 - - - - - - - -
KBFHEIFM_01441 3.95e-167 ykjA - - S - - - Protein of unknown function (DUF421)
KBFHEIFM_01442 1.84e-127 ykkA - - S - - - Protein of unknown function (DUF664)
KBFHEIFM_01443 1.46e-127 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KBFHEIFM_01444 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
KBFHEIFM_01445 1.36e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
KBFHEIFM_01446 1.66e-217 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
KBFHEIFM_01447 3.68e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KBFHEIFM_01448 1.6e-289 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KBFHEIFM_01449 1.97e-92 ohrA - - O - - - Organic hydroperoxide resistance protein
KBFHEIFM_01450 1.21e-98 ohrR - - K - - - COG1846 Transcriptional regulators
KBFHEIFM_01451 8.15e-94 ohrB - - O - - - Organic hydroperoxide resistance protein
KBFHEIFM_01452 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
KBFHEIFM_01453 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KBFHEIFM_01454 3.66e-226 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KBFHEIFM_01455 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KBFHEIFM_01456 1.04e-172 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
KBFHEIFM_01457 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KBFHEIFM_01458 5.67e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
KBFHEIFM_01459 2.44e-142 ykoF - - S - - - YKOF-related Family
KBFHEIFM_01460 2.13e-159 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KBFHEIFM_01461 8.98e-309 ykoH - - T - - - Histidine kinase
KBFHEIFM_01462 8.81e-142 ykoI - - S - - - Peptidase propeptide and YPEB domain
KBFHEIFM_01463 1.3e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
KBFHEIFM_01464 1.45e-08 - - - - - - - -
KBFHEIFM_01466 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
KBFHEIFM_01467 1.49e-70 tnrA - - K - - - transcriptional
KBFHEIFM_01468 1.63e-25 - - - - - - - -
KBFHEIFM_01469 3.04e-36 ykoL - - - - - - -
KBFHEIFM_01470 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
KBFHEIFM_01471 1.19e-281 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
KBFHEIFM_01472 2.48e-129 ykoP - - G - - - polysaccharide deacetylase
KBFHEIFM_01473 4.35e-198 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
KBFHEIFM_01474 0.0 ykoS - - - - - - -
KBFHEIFM_01475 5.72e-239 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
KBFHEIFM_01476 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
KBFHEIFM_01477 1.25e-204 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KBFHEIFM_01478 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
KBFHEIFM_01479 1.71e-143 ykoX - - S - - - membrane-associated protein
KBFHEIFM_01480 5.4e-226 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
KBFHEIFM_01481 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KBFHEIFM_01482 2.56e-209 rsgI - - S - - - Anti-sigma factor N-terminus
KBFHEIFM_01483 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
KBFHEIFM_01484 6.31e-159 ykrK - - S - - - Domain of unknown function (DUF1836)
KBFHEIFM_01485 3.97e-199 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
KBFHEIFM_01486 4.28e-309 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
KBFHEIFM_01488 8.76e-29 ykzE - - - - - - -
KBFHEIFM_01489 1.12e-242 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
KBFHEIFM_01490 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KBFHEIFM_01491 1.12e-114 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KBFHEIFM_01493 5.4e-252 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KBFHEIFM_01494 4.77e-291 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
KBFHEIFM_01495 1.99e-193 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KBFHEIFM_01496 6.56e-294 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KBFHEIFM_01497 2.29e-293 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
KBFHEIFM_01498 1.77e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KBFHEIFM_01499 1.51e-145 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
KBFHEIFM_01500 8.7e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KBFHEIFM_01501 3.6e-67 - - - S - - - Protein of unknown function (DUF1232)
KBFHEIFM_01503 1.18e-94 eag - - - - - - -
KBFHEIFM_01504 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
KBFHEIFM_01505 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
KBFHEIFM_01506 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
KBFHEIFM_01507 1.65e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
KBFHEIFM_01508 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
KBFHEIFM_01509 4.26e-230 ykvI - - S - - - membrane
KBFHEIFM_01510 1.11e-161 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KBFHEIFM_01511 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
KBFHEIFM_01512 3.56e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KBFHEIFM_01513 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KBFHEIFM_01514 7.06e-80 - - - K - - - HxlR-like helix-turn-helix
KBFHEIFM_01515 7.68e-172 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
KBFHEIFM_01516 2.69e-275 - - - M - - - Glycosyl transferases group 1
KBFHEIFM_01517 1.85e-48 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
KBFHEIFM_01518 2.5e-169 - - - G - - - Glycosyl hydrolases family 18
KBFHEIFM_01519 2.67e-62 ykvR - - S - - - Protein of unknown function (DUF3219)
KBFHEIFM_01520 5.43e-35 ykvS - - S - - - protein conserved in bacteria
KBFHEIFM_01521 2.6e-39 - - - - - - - -
KBFHEIFM_01522 9.09e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
KBFHEIFM_01523 1.12e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KBFHEIFM_01524 5.79e-117 stoA - - CO - - - thiol-disulfide
KBFHEIFM_01525 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
KBFHEIFM_01526 3.99e-09 - - - - - - - -
KBFHEIFM_01527 7.85e-266 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
KBFHEIFM_01529 3.28e-230 ykvZ - - K - - - Transcriptional regulator
KBFHEIFM_01531 3.41e-168 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
KBFHEIFM_01532 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KBFHEIFM_01533 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
KBFHEIFM_01534 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KBFHEIFM_01535 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
KBFHEIFM_01536 2.13e-257 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
KBFHEIFM_01537 2.24e-169 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KBFHEIFM_01538 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KBFHEIFM_01539 1.4e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
KBFHEIFM_01540 5.36e-172 ykwD - - J - - - protein with SCP PR1 domains
KBFHEIFM_01541 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
KBFHEIFM_01542 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KBFHEIFM_01543 1.78e-284 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KBFHEIFM_01544 1.05e-22 - - - - - - - -
KBFHEIFM_01545 4.95e-216 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
KBFHEIFM_01546 3.71e-110 ykyB - - S - - - YkyB-like protein
KBFHEIFM_01547 8.89e-306 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
KBFHEIFM_01548 7.1e-116 ykuD - - S - - - protein conserved in bacteria
KBFHEIFM_01549 5.77e-211 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
KBFHEIFM_01550 4.31e-181 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KBFHEIFM_01551 0.0 ybfG - - M - - - Putative peptidoglycan binding domain
KBFHEIFM_01553 1.76e-298 ykuI - - T - - - Diguanylate phosphodiesterase
KBFHEIFM_01554 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
KBFHEIFM_01555 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
KBFHEIFM_01556 7.83e-38 ykzF - - S - - - Antirepressor AbbA
KBFHEIFM_01557 5.15e-100 ykuL - - S - - - CBS domain
KBFHEIFM_01558 6.52e-216 ccpC - - K - - - Transcriptional regulator
KBFHEIFM_01559 7.72e-114 - - - C ko:K03839 - ko00000 Flavodoxin domain
KBFHEIFM_01560 1.33e-226 ykuO - - - - - - -
KBFHEIFM_01561 1.3e-104 fld - - C ko:K03839 - ko00000 Flavodoxin
KBFHEIFM_01562 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KBFHEIFM_01563 7.99e-276 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KBFHEIFM_01564 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
KBFHEIFM_01565 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
KBFHEIFM_01566 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
KBFHEIFM_01567 6.25e-106 ykuV - - CO - - - thiol-disulfide
KBFHEIFM_01568 4.71e-122 rok - - K - - - Repressor of ComK
KBFHEIFM_01569 5.72e-199 yknT - - - ko:K06437 - ko00000 -
KBFHEIFM_01570 9.21e-142 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
KBFHEIFM_01571 1.79e-243 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KBFHEIFM_01572 4.29e-313 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
KBFHEIFM_01573 3.44e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
KBFHEIFM_01574 6.61e-110 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
KBFHEIFM_01575 6.92e-45 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KBFHEIFM_01576 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
KBFHEIFM_01577 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
KBFHEIFM_01578 2.17e-149 yknW - - S - - - Yip1 domain
KBFHEIFM_01579 6.69e-233 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KBFHEIFM_01580 8.67e-160 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KBFHEIFM_01581 3.88e-265 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
KBFHEIFM_01582 7.41e-176 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
KBFHEIFM_01583 8.21e-215 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
KBFHEIFM_01584 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
KBFHEIFM_01585 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KBFHEIFM_01586 5.43e-52 ykoA - - - - - - -
KBFHEIFM_01587 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KBFHEIFM_01588 3.34e-214 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KBFHEIFM_01589 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
KBFHEIFM_01590 1.09e-18 - - - S - - - Uncharacterized protein YkpC
KBFHEIFM_01591 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
KBFHEIFM_01592 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
KBFHEIFM_01593 4.59e-307 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
KBFHEIFM_01594 3.42e-198 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
KBFHEIFM_01595 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
KBFHEIFM_01596 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KBFHEIFM_01597 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KBFHEIFM_01598 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
KBFHEIFM_01599 1.18e-186 ykrA - - S - - - hydrolases of the HAD superfamily
KBFHEIFM_01600 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KBFHEIFM_01601 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
KBFHEIFM_01602 6.82e-149 ykyA - - L - - - Putative cell-wall binding lipoprotein
KBFHEIFM_01603 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KBFHEIFM_01604 3.52e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KBFHEIFM_01605 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KBFHEIFM_01606 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KBFHEIFM_01607 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
KBFHEIFM_01608 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
KBFHEIFM_01609 1.34e-56 yktA - - S - - - Belongs to the UPF0223 family
KBFHEIFM_01610 5.28e-152 yktB - - S - - - Belongs to the UPF0637 family
KBFHEIFM_01611 4.48e-35 ykzI - - - - - - -
KBFHEIFM_01612 9.48e-195 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
KBFHEIFM_01613 1.48e-100 ykzC - - S - - - Acetyltransferase (GNAT) family
KBFHEIFM_01614 2.88e-220 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KBFHEIFM_01615 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
KBFHEIFM_01616 0.0 ylaA - - - - - - -
KBFHEIFM_01617 1.18e-55 ylaB - - - - - - -
KBFHEIFM_01618 3.56e-115 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KBFHEIFM_01620 4.02e-56 ylaE - - - - - - -
KBFHEIFM_01621 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
KBFHEIFM_01622 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
KBFHEIFM_01623 4.4e-63 ylaH - - S - - - YlaH-like protein
KBFHEIFM_01624 8.92e-44 ylaI - - S - - - protein conserved in bacteria
KBFHEIFM_01625 9.93e-126 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KBFHEIFM_01626 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
KBFHEIFM_01627 1.09e-110 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KBFHEIFM_01628 4.96e-219 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
KBFHEIFM_01629 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
KBFHEIFM_01630 8.22e-270 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
KBFHEIFM_01631 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KBFHEIFM_01632 2.44e-213 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
KBFHEIFM_01633 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KBFHEIFM_01634 2.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
KBFHEIFM_01635 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KBFHEIFM_01636 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
KBFHEIFM_01637 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
KBFHEIFM_01638 1.48e-214 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
KBFHEIFM_01639 1.61e-81 ylbA - - S - - - YugN-like family
KBFHEIFM_01640 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
KBFHEIFM_01641 3.61e-255 ylbC - - S - - - protein with SCP PR1 domains
KBFHEIFM_01642 3.24e-89 ylbD - - S - - - Putative coat protein
KBFHEIFM_01643 1.73e-48 ylbE - - S - - - YlbE-like protein
KBFHEIFM_01644 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
KBFHEIFM_01645 5.1e-51 ylbG - - S - - - UPF0298 protein
KBFHEIFM_01646 1.43e-124 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
KBFHEIFM_01647 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KBFHEIFM_01648 1.58e-281 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
KBFHEIFM_01649 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
KBFHEIFM_01650 4.34e-238 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
KBFHEIFM_01651 6.13e-18 yqgA - - - - - - -
KBFHEIFM_01652 2.19e-152 ylbM - - S - - - Belongs to the UPF0348 family
KBFHEIFM_01654 6.94e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
KBFHEIFM_01655 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
KBFHEIFM_01656 4.72e-107 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
KBFHEIFM_01657 1.33e-115 ylbP - - K - - - n-acetyltransferase
KBFHEIFM_01658 4.57e-214 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KBFHEIFM_01659 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KBFHEIFM_01660 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
KBFHEIFM_01661 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KBFHEIFM_01662 3.42e-68 ftsL - - D - - - Essential cell division protein
KBFHEIFM_01663 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
KBFHEIFM_01664 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
KBFHEIFM_01665 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KBFHEIFM_01666 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KBFHEIFM_01667 3.48e-68 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KBFHEIFM_01668 7.18e-221 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KBFHEIFM_01669 1.47e-101 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
KBFHEIFM_01670 9.43e-45 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
KBFHEIFM_01671 2.12e-95 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KBFHEIFM_01672 5.04e-86 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KBFHEIFM_01673 1.3e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
KBFHEIFM_01674 2.41e-171 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KBFHEIFM_01675 1.35e-143 ylxW - - S - - - protein conserved in bacteria
KBFHEIFM_01676 1.03e-123 ylxX - - S - - - protein conserved in bacteria
KBFHEIFM_01677 2.56e-74 sbp - - S - - - small basic protein
KBFHEIFM_01678 4.01e-298 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KBFHEIFM_01679 1.61e-219 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KBFHEIFM_01680 0.0 - - - Q ko:K15662 ko01054,map01054 ko00000,ko00001,ko01008 Non-ribosomal peptide synthetase modules and related proteins
KBFHEIFM_01681 0.0 - - - Q - - - Non-ribosomal peptide synthetase modules and related proteins
KBFHEIFM_01682 1.36e-53 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KBFHEIFM_01683 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
KBFHEIFM_01685 2.11e-220 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
KBFHEIFM_01686 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KBFHEIFM_01687 7.99e-180 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KBFHEIFM_01688 4.49e-188 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
KBFHEIFM_01689 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
KBFHEIFM_01690 3.58e-51 ylmC - - S - - - sporulation protein
KBFHEIFM_01691 5.94e-200 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
KBFHEIFM_01692 9.03e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KBFHEIFM_01693 5.44e-88 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KBFHEIFM_01694 1.22e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
KBFHEIFM_01695 1.49e-178 ylmH - - S - - - conserved protein, contains S4-like domain
KBFHEIFM_01696 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
KBFHEIFM_01697 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KBFHEIFM_01698 9.18e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
KBFHEIFM_01699 2.71e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KBFHEIFM_01700 3.24e-221 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
KBFHEIFM_01701 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KBFHEIFM_01702 7.49e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
KBFHEIFM_01703 8.15e-211 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
KBFHEIFM_01704 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KBFHEIFM_01705 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
KBFHEIFM_01706 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
KBFHEIFM_01707 2.91e-180 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KBFHEIFM_01708 6.05e-221 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KBFHEIFM_01709 9.32e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KBFHEIFM_01710 2.57e-148 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KBFHEIFM_01712 3.44e-181 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
KBFHEIFM_01713 6.01e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
KBFHEIFM_01714 2.15e-284 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
KBFHEIFM_01715 1.59e-141 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
KBFHEIFM_01716 5.9e-185 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
KBFHEIFM_01717 1.19e-186 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
KBFHEIFM_01718 2.28e-108 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
KBFHEIFM_01719 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
KBFHEIFM_01720 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
KBFHEIFM_01721 4.86e-201 yloC - - S - - - stress-induced protein
KBFHEIFM_01722 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
KBFHEIFM_01723 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
KBFHEIFM_01724 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KBFHEIFM_01725 5.13e-286 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KBFHEIFM_01726 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KBFHEIFM_01727 4.8e-109 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KBFHEIFM_01728 1.22e-223 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KBFHEIFM_01729 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KBFHEIFM_01730 8.79e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KBFHEIFM_01731 4.13e-179 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
KBFHEIFM_01732 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
KBFHEIFM_01733 1.37e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KBFHEIFM_01734 1.34e-152 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
KBFHEIFM_01735 8.13e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
KBFHEIFM_01736 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
KBFHEIFM_01737 3.65e-78 yloU - - S - - - protein conserved in bacteria
KBFHEIFM_01738 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
KBFHEIFM_01739 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
KBFHEIFM_01740 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
KBFHEIFM_01741 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KBFHEIFM_01742 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
KBFHEIFM_01743 8.33e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KBFHEIFM_01744 3.09e-217 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
KBFHEIFM_01745 3.5e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
KBFHEIFM_01746 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
KBFHEIFM_01747 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KBFHEIFM_01748 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
KBFHEIFM_01749 3.95e-226 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KBFHEIFM_01750 1.67e-114 - - - - - - - -
KBFHEIFM_01751 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KBFHEIFM_01752 3.95e-308 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KBFHEIFM_01753 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
KBFHEIFM_01754 2.95e-50 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
KBFHEIFM_01755 5.89e-81 ylqD - - S - - - YlqD protein
KBFHEIFM_01756 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KBFHEIFM_01757 6.9e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
KBFHEIFM_01758 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KBFHEIFM_01759 1.2e-201 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KBFHEIFM_01760 2.89e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KBFHEIFM_01761 0.0 ylqG - - - - - - -
KBFHEIFM_01762 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
KBFHEIFM_01763 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
KBFHEIFM_01764 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KBFHEIFM_01765 2.66e-217 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
KBFHEIFM_01766 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KBFHEIFM_01767 5.45e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KBFHEIFM_01768 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
KBFHEIFM_01769 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KBFHEIFM_01770 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KBFHEIFM_01771 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KBFHEIFM_01772 1.62e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
KBFHEIFM_01773 7.54e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
KBFHEIFM_01774 1.58e-52 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
KBFHEIFM_01775 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
KBFHEIFM_01776 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KBFHEIFM_01777 1.92e-144 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
KBFHEIFM_01778 1.74e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
KBFHEIFM_01779 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
KBFHEIFM_01780 5.08e-84 ylxF - - S - - - MgtE intracellular N domain
KBFHEIFM_01781 1.28e-311 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
KBFHEIFM_01782 3.99e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
KBFHEIFM_01783 1.09e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
KBFHEIFM_01784 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
KBFHEIFM_01785 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KBFHEIFM_01786 4.29e-241 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KBFHEIFM_01787 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
KBFHEIFM_01788 7.87e-137 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
KBFHEIFM_01789 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
KBFHEIFM_01790 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
KBFHEIFM_01791 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
KBFHEIFM_01792 2.74e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KBFHEIFM_01793 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KBFHEIFM_01794 2.3e-255 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
KBFHEIFM_01795 6.33e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
KBFHEIFM_01796 7.38e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
KBFHEIFM_01797 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
KBFHEIFM_01798 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
KBFHEIFM_01799 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
KBFHEIFM_01800 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
KBFHEIFM_01801 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KBFHEIFM_01802 6.91e-101 ylxL - - - - - - -
KBFHEIFM_01803 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
KBFHEIFM_01804 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KBFHEIFM_01805 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
KBFHEIFM_01806 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KBFHEIFM_01807 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KBFHEIFM_01808 5.77e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
KBFHEIFM_01809 3.26e-275 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
KBFHEIFM_01810 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
KBFHEIFM_01811 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KBFHEIFM_01812 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KBFHEIFM_01813 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
KBFHEIFM_01814 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
KBFHEIFM_01815 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
KBFHEIFM_01816 6.16e-63 ylxQ - - J - - - ribosomal protein
KBFHEIFM_01817 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KBFHEIFM_01818 7.83e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
KBFHEIFM_01819 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KBFHEIFM_01820 4.96e-219 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KBFHEIFM_01821 1.1e-230 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
KBFHEIFM_01822 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KBFHEIFM_01823 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KBFHEIFM_01824 1.69e-231 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
KBFHEIFM_01825 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
KBFHEIFM_01826 1.53e-56 ymxH - - S - - - YlmC YmxH family
KBFHEIFM_01827 5.3e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
KBFHEIFM_01828 3.33e-140 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
KBFHEIFM_01829 9.62e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KBFHEIFM_01830 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
KBFHEIFM_01831 3.7e-200 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KBFHEIFM_01832 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KBFHEIFM_01833 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
KBFHEIFM_01834 8.23e-43 - - - S - - - YlzJ-like protein
KBFHEIFM_01835 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
KBFHEIFM_01836 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
KBFHEIFM_01837 2.08e-267 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KBFHEIFM_01838 4.03e-300 albE - - S - - - Peptidase M16
KBFHEIFM_01839 3.23e-307 ymfH - - S - - - zinc protease
KBFHEIFM_01840 1.49e-166 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
KBFHEIFM_01841 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
KBFHEIFM_01842 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
KBFHEIFM_01843 3.05e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
KBFHEIFM_01844 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KBFHEIFM_01845 3.71e-300 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
KBFHEIFM_01846 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KBFHEIFM_01847 4e-280 pbpX - - V - - - Beta-lactamase
KBFHEIFM_01848 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
KBFHEIFM_01849 6.18e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
KBFHEIFM_01850 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
KBFHEIFM_01851 4.81e-252 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
KBFHEIFM_01852 2.8e-276 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KBFHEIFM_01853 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KBFHEIFM_01854 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
KBFHEIFM_01855 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
KBFHEIFM_01856 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KBFHEIFM_01857 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KBFHEIFM_01858 1.64e-92 - - - S - - - Regulatory protein YrvL
KBFHEIFM_01859 9.3e-126 ymcC - - S - - - Membrane
KBFHEIFM_01860 1.2e-140 pksA - - K - - - Transcriptional regulator
KBFHEIFM_01861 4.02e-167 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
KBFHEIFM_01862 5.32e-208 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
KBFHEIFM_01864 2.33e-236 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
KBFHEIFM_01865 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
KBFHEIFM_01866 5.46e-51 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
KBFHEIFM_01867 4.36e-303 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KBFHEIFM_01868 1.13e-312 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
KBFHEIFM_01869 1.44e-183 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
KBFHEIFM_01870 4.29e-174 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
KBFHEIFM_01871 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
KBFHEIFM_01872 0.0 - - - Q ko:K13612 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KBFHEIFM_01873 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
KBFHEIFM_01874 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
KBFHEIFM_01875 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
KBFHEIFM_01876 2.05e-296 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
KBFHEIFM_01877 2.8e-81 ymzB - - - - - - -
KBFHEIFM_01878 4.8e-210 - - - S - - - Metallo-beta-lactamase superfamily
KBFHEIFM_01879 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
KBFHEIFM_01881 3.96e-163 ymaC - - S - - - Replication protein
KBFHEIFM_01882 1.03e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
KBFHEIFM_01883 1.57e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
KBFHEIFM_01884 1.21e-67 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
KBFHEIFM_01886 5.41e-76 ymaF - - S - - - YmaF family
KBFHEIFM_01887 9.69e-224 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KBFHEIFM_01888 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
KBFHEIFM_01889 1.63e-31 - - - - - - - -
KBFHEIFM_01890 1.2e-30 ymzA - - - - - - -
KBFHEIFM_01891 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
KBFHEIFM_01892 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KBFHEIFM_01893 4.74e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KBFHEIFM_01894 2.24e-141 - - - - - - - -
KBFHEIFM_01895 9.94e-151 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
KBFHEIFM_01896 5.4e-225 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
KBFHEIFM_01897 1.05e-292 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KBFHEIFM_01898 1.67e-310 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
KBFHEIFM_01899 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
KBFHEIFM_01900 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
KBFHEIFM_01901 1.19e-78 - - - L - - - Belongs to the 'phage' integrase family
KBFHEIFM_01902 1.92e-120 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
KBFHEIFM_01903 2.98e-21 - - - S - - - Bacteriophage holin family
KBFHEIFM_01904 7.07e-31 - - - S - - - Pfam:Phage_holin_4_1
KBFHEIFM_01905 3.78e-136 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
KBFHEIFM_01906 1.83e-66 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
KBFHEIFM_01907 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
KBFHEIFM_01908 1.88e-27 - - - D - - - nuclear chromosome segregation
KBFHEIFM_01910 8.58e-50 - - - T - - - Histidine kinase
KBFHEIFM_01911 2.39e-13 - - - L - - - phage terminase small subunit
KBFHEIFM_01912 1.28e-68 - - - L - - - phage terminase small subunit
KBFHEIFM_01913 3.03e-14 - - - S - - - Terminase
KBFHEIFM_01917 1.82e-15 - - - - - - - -
KBFHEIFM_01919 1.03e-19 - - - - - - - -
KBFHEIFM_01920 6.58e-109 - - - - - - - -
KBFHEIFM_01921 1.39e-49 - - - - - - - -
KBFHEIFM_01922 1.18e-115 - - - G - - - SMI1-KNR4 cell-wall
KBFHEIFM_01923 6.08e-181 ynaC - - - - - - -
KBFHEIFM_01924 3.38e-125 ynaD - - J - - - Acetyltransferase (GNAT) domain
KBFHEIFM_01926 1.14e-93 - - - S - - - CAAX protease self-immunity
KBFHEIFM_01927 1.32e-10 ywlA - - S - - - Uncharacterised protein family (UPF0715)
KBFHEIFM_01928 5.14e-27 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
KBFHEIFM_01929 6.61e-144 - - - S - - - Domain of unknown function (DUF3885)
KBFHEIFM_01930 1.1e-74 ynaF - - - - - - -
KBFHEIFM_01932 1.28e-102 - - - E - - - phosphoribosylanthranilate isomerase activity
KBFHEIFM_01933 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
KBFHEIFM_01934 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
KBFHEIFM_01935 2.48e-275 xylR - - GK - - - ROK family
KBFHEIFM_01936 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
KBFHEIFM_01937 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
KBFHEIFM_01938 1.24e-145 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
KBFHEIFM_01939 3.64e-313 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KBFHEIFM_01940 3.05e-281 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KBFHEIFM_01941 3.44e-110 - - - S - - - Protein of unknown function (DUF2691)
KBFHEIFM_01942 3.01e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
KBFHEIFM_01943 7.54e-22 - - - - - - - -
KBFHEIFM_01946 9.21e-209 - - - S - - - Thymidylate synthase
KBFHEIFM_01948 3.35e-167 - - - S - - - Domain of unknown function, YrpD
KBFHEIFM_01951 1.96e-33 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
KBFHEIFM_01952 8.92e-96 - - - - - - - -
KBFHEIFM_01953 3.12e-104 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
KBFHEIFM_01956 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
KBFHEIFM_01957 1.95e-250 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
KBFHEIFM_01958 9.64e-290 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
KBFHEIFM_01959 9.15e-199 yndG - - S - - - DoxX-like family
KBFHEIFM_01960 2.87e-147 - - - S - - - Domain of unknown function (DUF4166)
KBFHEIFM_01961 0.0 yndJ - - S - - - YndJ-like protein
KBFHEIFM_01963 8e-176 yndL - - S - - - Replication protein
KBFHEIFM_01964 1.32e-96 yndM - - S - - - Protein of unknown function (DUF2512)
KBFHEIFM_01965 4.44e-104 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
KBFHEIFM_01966 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KBFHEIFM_01967 8.5e-65 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
KBFHEIFM_01968 2.29e-144 yneB - - L - - - resolvase
KBFHEIFM_01969 1.15e-43 ynzC - - S - - - UPF0291 protein
KBFHEIFM_01970 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KBFHEIFM_01971 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
KBFHEIFM_01972 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
KBFHEIFM_01973 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
KBFHEIFM_01974 4.13e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
KBFHEIFM_01975 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
KBFHEIFM_01976 7.21e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
KBFHEIFM_01977 1.14e-96 yneK - - S - - - Protein of unknown function (DUF2621)
KBFHEIFM_01978 2.35e-84 cotM - - O ko:K06335 - ko00000 Spore coat protein
KBFHEIFM_01979 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
KBFHEIFM_01980 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
KBFHEIFM_01981 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KBFHEIFM_01982 2.53e-118 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KBFHEIFM_01983 9.26e-10 - - - S - - - Fur-regulated basic protein B
KBFHEIFM_01985 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
KBFHEIFM_01986 1.4e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
KBFHEIFM_01987 1.63e-71 yneQ - - - - - - -
KBFHEIFM_01988 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
KBFHEIFM_01989 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KBFHEIFM_01990 1.21e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
KBFHEIFM_01991 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KBFHEIFM_01992 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KBFHEIFM_01993 1.82e-18 - - - - - - - -
KBFHEIFM_01994 1.06e-75 ynfC - - - - - - -
KBFHEIFM_01995 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
KBFHEIFM_01996 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
KBFHEIFM_01998 7.88e-316 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
KBFHEIFM_01999 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
KBFHEIFM_02000 3.48e-103 yngA - - S - - - membrane
KBFHEIFM_02001 2.74e-210 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
KBFHEIFM_02002 2.01e-134 yngC - - S - - - membrane-associated protein
KBFHEIFM_02003 1.28e-296 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
KBFHEIFM_02004 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KBFHEIFM_02005 7.04e-174 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
KBFHEIFM_02006 6.73e-212 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
KBFHEIFM_02007 2.4e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
KBFHEIFM_02008 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
KBFHEIFM_02009 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KBFHEIFM_02010 6.68e-262 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
KBFHEIFM_02011 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
KBFHEIFM_02012 1.01e-82 yngL - - S - - - Protein of unknown function (DUF1360)
KBFHEIFM_02013 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
KBFHEIFM_02014 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KBFHEIFM_02015 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KBFHEIFM_02016 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KBFHEIFM_02017 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KBFHEIFM_02018 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
KBFHEIFM_02019 6.44e-239 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
KBFHEIFM_02020 9.8e-313 yoeA - - V - - - MATE efflux family protein
KBFHEIFM_02021 7.14e-128 yoeB - - S - - - IseA DL-endopeptidase inhibitor
KBFHEIFM_02023 1.14e-124 - - - L - - - Integrase
KBFHEIFM_02024 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
KBFHEIFM_02025 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
KBFHEIFM_02026 6.17e-201 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
KBFHEIFM_02027 4.18e-237 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
KBFHEIFM_02028 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
KBFHEIFM_02029 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
KBFHEIFM_02030 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
KBFHEIFM_02031 1.35e-261 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KBFHEIFM_02032 2.72e-185 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KBFHEIFM_02033 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
KBFHEIFM_02034 3.77e-158 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
KBFHEIFM_02035 1.15e-54 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
KBFHEIFM_02036 1.34e-185 yoxB - - - - - - -
KBFHEIFM_02037 5.91e-125 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KBFHEIFM_02038 1.11e-300 yoaB - - EGP - - - the major facilitator superfamily
KBFHEIFM_02039 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
KBFHEIFM_02040 3.41e-243 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KBFHEIFM_02041 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KBFHEIFM_02042 3.48e-43 yoaF - - - - - - -
KBFHEIFM_02043 5.83e-216 - - - EGP ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KBFHEIFM_02044 3.41e-259 - - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
KBFHEIFM_02045 3.73e-193 - 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
KBFHEIFM_02046 1.99e-114 degA - - K - - - Transcriptional regulator
KBFHEIFM_02047 6.86e-12 - - - - - - - -
KBFHEIFM_02048 1.46e-19 - - - - - - - -
KBFHEIFM_02049 6.78e-61 - - - S - - - Protein of unknown function (DUF4025)
KBFHEIFM_02050 8.71e-287 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
KBFHEIFM_02051 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
KBFHEIFM_02052 2.61e-171 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
KBFHEIFM_02053 2.01e-142 yoaK - - S - - - Membrane
KBFHEIFM_02054 3.38e-251 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
KBFHEIFM_02055 4.88e-169 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
KBFHEIFM_02057 1.54e-293 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
KBFHEIFM_02059 9.48e-188 yoaP - - K - - - YoaP-like
KBFHEIFM_02060 6.07e-87 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
KBFHEIFM_02061 6.51e-114 - - - - - - - -
KBFHEIFM_02062 3.63e-218 yoaR - - V - - - vancomycin resistance protein
KBFHEIFM_02063 1.31e-97 yoaS - - S - - - Protein of unknown function (DUF2975)
KBFHEIFM_02064 7.38e-50 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
KBFHEIFM_02065 7.76e-189 yoaT - - S - - - Protein of unknown function (DUF817)
KBFHEIFM_02066 1.11e-201 yoaU - - K - - - LysR substrate binding domain
KBFHEIFM_02067 1.06e-200 yoaV - - EG - - - EamA-like transporter family
KBFHEIFM_02068 5.63e-102 yoaW - - - - - - -
KBFHEIFM_02069 1.15e-145 lin0465 - - S - - - DJ-1/PfpI family
KBFHEIFM_02070 4.72e-211 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
KBFHEIFM_02073 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
KBFHEIFM_02074 1.07e-156 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
KBFHEIFM_02075 7.35e-17 - - - - - - - -
KBFHEIFM_02081 1.56e-12 ywlA - - S - - - Uncharacterised protein family (UPF0715)
KBFHEIFM_02083 1.03e-85 - - - O - - - Torsin
KBFHEIFM_02084 1.85e-49 - - - - - - - -
KBFHEIFM_02086 4.81e-152 - - - O - - - Subtilase family
KBFHEIFM_02087 5e-134 - - - - - - - -
KBFHEIFM_02088 3.23e-86 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
KBFHEIFM_02089 1.24e-22 - - - - - - - -
KBFHEIFM_02091 1.95e-135 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
KBFHEIFM_02093 1.95e-26 - - - - - - - -
KBFHEIFM_02094 1.13e-20 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
KBFHEIFM_02095 2.8e-132 yokH - - G - - - SMI1 / KNR4 family
KBFHEIFM_02096 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
KBFHEIFM_02097 8.66e-70 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
KBFHEIFM_02098 2.13e-174 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
KBFHEIFM_02099 2.41e-179 - - - J - - - FR47-like protein
KBFHEIFM_02100 3.09e-127 yobS - - K - - - Transcriptional regulator
KBFHEIFM_02101 1.34e-169 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
KBFHEIFM_02102 8.64e-112 - - - K - - - Bacterial transcription activator, effector binding domain
KBFHEIFM_02103 2.68e-225 yobV - - K - - - WYL domain
KBFHEIFM_02104 3.01e-120 yobW - - - - - - -
KBFHEIFM_02105 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
KBFHEIFM_02106 3.28e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KBFHEIFM_02107 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
KBFHEIFM_02108 2.6e-185 - - - - - - - -
KBFHEIFM_02109 1.08e-121 yocC - - - - - - -
KBFHEIFM_02110 2.73e-240 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
KBFHEIFM_02111 6.62e-257 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
KBFHEIFM_02112 2.37e-250 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KBFHEIFM_02113 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KBFHEIFM_02114 2.89e-175 yocH - - M - - - COG1388 FOG LysM repeat
KBFHEIFM_02115 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
KBFHEIFM_02116 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KBFHEIFM_02117 1.42e-107 yocK - - T - - - general stress protein
KBFHEIFM_02118 3.02e-70 yocL - - - - - - -
KBFHEIFM_02119 2.02e-43 - - - - - - - -
KBFHEIFM_02120 2.69e-114 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
KBFHEIFM_02121 2.94e-55 yozN - - - - - - -
KBFHEIFM_02122 1.83e-49 yocN - - - - - - -
KBFHEIFM_02123 2.17e-74 yozO - - S - - - Bacterial PH domain
KBFHEIFM_02124 1.91e-42 yozC - - - - - - -
KBFHEIFM_02125 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KBFHEIFM_02126 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
KBFHEIFM_02127 6.49e-210 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
KBFHEIFM_02128 6.18e-300 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KBFHEIFM_02129 9.48e-214 yocS - - S ko:K03453 - ko00000 -transporter
KBFHEIFM_02130 2.59e-264 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
KBFHEIFM_02131 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
KBFHEIFM_02132 0.0 yojO - - P - - - Von Willebrand factor
KBFHEIFM_02133 1.28e-205 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
KBFHEIFM_02134 6.01e-141 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KBFHEIFM_02135 1.3e-267 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
KBFHEIFM_02136 2.29e-293 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
KBFHEIFM_02137 4.31e-141 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KBFHEIFM_02139 2.93e-313 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
KBFHEIFM_02140 1.01e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KBFHEIFM_02141 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
KBFHEIFM_02142 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
KBFHEIFM_02143 1.85e-58 - - - - - - - -
KBFHEIFM_02144 1.92e-206 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
KBFHEIFM_02145 7.43e-107 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
KBFHEIFM_02146 1.95e-14 - - - - - - - -
KBFHEIFM_02147 2.65e-289 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
KBFHEIFM_02148 5.64e-84 iolK - - S - - - tautomerase
KBFHEIFM_02149 2.63e-73 yodB - - K - - - transcriptional
KBFHEIFM_02150 1.11e-139 yodC - - C - - - nitroreductase
KBFHEIFM_02151 8.86e-145 yahD - - S ko:K06999 - ko00000 Carboxylesterase
KBFHEIFM_02152 5.61e-222 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
KBFHEIFM_02153 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
KBFHEIFM_02154 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KBFHEIFM_02155 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
KBFHEIFM_02156 3.69e-167 yodH - - Q - - - Methyltransferase
KBFHEIFM_02157 5.91e-42 yodI - - - - - - -
KBFHEIFM_02158 4.46e-188 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
KBFHEIFM_02159 3.4e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
KBFHEIFM_02160 2.08e-12 - - - - - - - -
KBFHEIFM_02161 1.17e-71 yodL - - S - - - YodL-like
KBFHEIFM_02162 4.02e-138 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
KBFHEIFM_02163 5.18e-34 yozD - - S - - - YozD-like protein
KBFHEIFM_02165 1.29e-159 yodN - - - - - - -
KBFHEIFM_02166 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
KBFHEIFM_02167 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
KBFHEIFM_02168 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
KBFHEIFM_02169 1.24e-195 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
KBFHEIFM_02170 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
KBFHEIFM_02171 2.71e-152 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KBFHEIFM_02172 4.64e-159 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KBFHEIFM_02173 9.36e-317 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KBFHEIFM_02175 6.61e-183 yiiD - - K ko:K06323 - ko00000 acetyltransferase
KBFHEIFM_02176 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
KBFHEIFM_02177 3.04e-59 cgeC - - - ko:K06321 - ko00000 -
KBFHEIFM_02178 5.57e-86 cgeA - - - ko:K06319 - ko00000 -
KBFHEIFM_02179 2.43e-239 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
KBFHEIFM_02180 1.56e-277 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
KBFHEIFM_02181 1.66e-157 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
KBFHEIFM_02182 7.13e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
KBFHEIFM_02183 8.41e-134 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KBFHEIFM_02184 4.14e-94 ypoP - - K - - - transcriptional
KBFHEIFM_02185 1.36e-287 mepA - - V - - - MATE efflux family protein
KBFHEIFM_02186 2.13e-40 ypmT - - S - - - Uncharacterized ympT
KBFHEIFM_02187 6.8e-129 ypmS - - S - - - protein conserved in bacteria
KBFHEIFM_02188 1.28e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
KBFHEIFM_02189 3.23e-139 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
KBFHEIFM_02190 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
KBFHEIFM_02191 3.64e-310 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KBFHEIFM_02192 1.4e-236 yplP - - K - - - Transcriptional regulator
KBFHEIFM_02193 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
KBFHEIFM_02194 1.71e-145 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KBFHEIFM_02195 9.96e-124 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KBFHEIFM_02196 1.21e-201 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KBFHEIFM_02197 8.91e-121 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
KBFHEIFM_02198 3.47e-148 ypjP - - S - - - YpjP-like protein
KBFHEIFM_02199 6.15e-187 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
KBFHEIFM_02200 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
KBFHEIFM_02201 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
KBFHEIFM_02202 9.9e-205 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
KBFHEIFM_02203 2.23e-136 yagB - - S ko:K06950 - ko00000 phosphohydrolase
KBFHEIFM_02204 2.58e-113 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
KBFHEIFM_02205 1.28e-226 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KBFHEIFM_02207 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
KBFHEIFM_02208 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
KBFHEIFM_02209 1.17e-22 degR - - - - - - -
KBFHEIFM_02210 1.05e-40 - - - S - - - Protein of unknown function (DUF2564)
KBFHEIFM_02211 7.99e-41 ypeQ - - S - - - Zinc-finger
KBFHEIFM_02212 2.31e-162 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
KBFHEIFM_02213 3.27e-136 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KBFHEIFM_02214 1.6e-89 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
KBFHEIFM_02215 5.23e-05 - - - - ko:K06429 - ko00000 -
KBFHEIFM_02216 2.26e-213 ypcP - - L - - - 5'3' exonuclease
KBFHEIFM_02217 1.08e-11 - - - - - - - -
KBFHEIFM_02218 4.07e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
KBFHEIFM_02219 0.0 ypbR - - S - - - Dynamin family
KBFHEIFM_02220 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
KBFHEIFM_02221 5.09e-263 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
KBFHEIFM_02222 1.17e-289 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
KBFHEIFM_02223 6.7e-128 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KBFHEIFM_02224 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KBFHEIFM_02225 3.35e-223 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
KBFHEIFM_02226 5.97e-132 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
KBFHEIFM_02227 2.83e-237 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
KBFHEIFM_02228 1.19e-234 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
KBFHEIFM_02229 1.2e-202 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KBFHEIFM_02230 1.88e-175 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KBFHEIFM_02231 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
KBFHEIFM_02233 2.72e-284 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
KBFHEIFM_02234 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KBFHEIFM_02235 2.06e-129 ypsA - - S - - - Belongs to the UPF0398 family
KBFHEIFM_02236 2.94e-300 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
KBFHEIFM_02237 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
KBFHEIFM_02238 6.45e-111 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
KBFHEIFM_02239 4.33e-95 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
KBFHEIFM_02240 8.72e-68 yppG - - S - - - YppG-like protein
KBFHEIFM_02241 9.21e-11 - - - S - - - YppF-like protein
KBFHEIFM_02242 7.9e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
KBFHEIFM_02245 5.3e-240 yppC - - S - - - Protein of unknown function (DUF2515)
KBFHEIFM_02246 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KBFHEIFM_02247 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KBFHEIFM_02248 1.17e-120 ypoC - - - - - - -
KBFHEIFM_02249 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KBFHEIFM_02250 6.62e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
KBFHEIFM_02251 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
KBFHEIFM_02252 7.24e-284 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
KBFHEIFM_02253 2.27e-103 ypmB - - S - - - protein conserved in bacteria
KBFHEIFM_02254 6.21e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
KBFHEIFM_02255 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
KBFHEIFM_02256 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KBFHEIFM_02257 5.47e-200 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KBFHEIFM_02258 4.85e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
KBFHEIFM_02259 1.63e-232 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KBFHEIFM_02260 4.5e-280 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KBFHEIFM_02261 8.54e-268 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
KBFHEIFM_02262 1.1e-165 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
KBFHEIFM_02263 8.45e-92 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
KBFHEIFM_02264 2.4e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KBFHEIFM_02265 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
KBFHEIFM_02266 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KBFHEIFM_02267 6.84e-183 ypjB - - S - - - sporulation protein
KBFHEIFM_02268 3.84e-124 ypjA - - S - - - membrane
KBFHEIFM_02269 1.35e-189 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
KBFHEIFM_02270 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
KBFHEIFM_02271 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
KBFHEIFM_02272 2.26e-99 ypiF - - S - - - Protein of unknown function (DUF2487)
KBFHEIFM_02273 1.83e-129 ypiB - - S - - - Belongs to the UPF0302 family
KBFHEIFM_02274 2.5e-297 ypiA - - S - - - COG0457 FOG TPR repeat
KBFHEIFM_02275 7.8e-299 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KBFHEIFM_02276 1.21e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
KBFHEIFM_02277 3.54e-256 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KBFHEIFM_02278 1.28e-184 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KBFHEIFM_02279 1.09e-293 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KBFHEIFM_02280 5.25e-149 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
KBFHEIFM_02281 2.07e-145 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
KBFHEIFM_02282 6.08e-230 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KBFHEIFM_02283 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KBFHEIFM_02284 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
KBFHEIFM_02285 4.7e-262 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KBFHEIFM_02286 1.44e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KBFHEIFM_02287 3.69e-183 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
KBFHEIFM_02288 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KBFHEIFM_02289 1.17e-248 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KBFHEIFM_02290 1.34e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KBFHEIFM_02291 8.72e-178 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
KBFHEIFM_02292 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
KBFHEIFM_02293 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
KBFHEIFM_02294 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KBFHEIFM_02295 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KBFHEIFM_02296 2.5e-175 yphF - - - - - - -
KBFHEIFM_02297 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
KBFHEIFM_02298 2.57e-230 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
KBFHEIFM_02299 4.77e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
KBFHEIFM_02300 8.69e-40 ypzH - - - - - - -
KBFHEIFM_02301 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
KBFHEIFM_02302 2.73e-134 yphA - - - - - - -
KBFHEIFM_02303 1.13e-11 - - - S - - - YpzI-like protein
KBFHEIFM_02304 5.43e-234 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KBFHEIFM_02305 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
KBFHEIFM_02306 2.36e-145 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
KBFHEIFM_02307 1.74e-32 - - - S - - - Family of unknown function (DUF5359)
KBFHEIFM_02308 4.63e-144 ypfA - - M - - - Flagellar protein YcgR
KBFHEIFM_02309 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
KBFHEIFM_02310 6.93e-208 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
KBFHEIFM_02311 1.76e-153 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
KBFHEIFM_02312 2.99e-223 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
KBFHEIFM_02313 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
KBFHEIFM_02314 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KBFHEIFM_02315 3.56e-187 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
KBFHEIFM_02316 4.08e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
KBFHEIFM_02317 3.99e-134 ypbE - - M - - - Lysin motif
KBFHEIFM_02318 3.55e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
KBFHEIFM_02319 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
KBFHEIFM_02320 2.48e-252 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
KBFHEIFM_02321 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
KBFHEIFM_02322 3.59e-121 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KBFHEIFM_02323 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KBFHEIFM_02324 4.79e-174 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KBFHEIFM_02325 4.12e-238 rsiX - - - - - - -
KBFHEIFM_02326 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KBFHEIFM_02327 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KBFHEIFM_02328 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KBFHEIFM_02329 4.67e-279 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
KBFHEIFM_02330 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
KBFHEIFM_02331 5.04e-127 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
KBFHEIFM_02332 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
KBFHEIFM_02333 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
KBFHEIFM_02334 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
KBFHEIFM_02335 9.67e-272 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KBFHEIFM_02336 2.92e-126 ypuI - - S - - - Protein of unknown function (DUF3907)
KBFHEIFM_02337 9.54e-134 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KBFHEIFM_02338 9.09e-166 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KBFHEIFM_02339 1.7e-118 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
KBFHEIFM_02340 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KBFHEIFM_02341 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KBFHEIFM_02342 1.27e-291 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KBFHEIFM_02343 1.24e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
KBFHEIFM_02344 2.41e-259 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KBFHEIFM_02345 5.98e-72 ypuD - - - - - - -
KBFHEIFM_02346 3.39e-132 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KBFHEIFM_02347 1.28e-45 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
KBFHEIFM_02349 3.82e-09 - - - S - - - SNARE associated Golgi protein
KBFHEIFM_02351 6.1e-11 - - - M - - - Domain of Unknown Function (DUF1259)
KBFHEIFM_02353 2.61e-34 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KBFHEIFM_02358 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KBFHEIFM_02359 3.12e-192 ypuA - - S - - - Secreted protein
KBFHEIFM_02360 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KBFHEIFM_02361 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
KBFHEIFM_02362 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
KBFHEIFM_02363 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
KBFHEIFM_02364 6.02e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
KBFHEIFM_02365 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
KBFHEIFM_02366 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
KBFHEIFM_02367 1.15e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
KBFHEIFM_02368 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KBFHEIFM_02369 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
KBFHEIFM_02370 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
KBFHEIFM_02371 3.37e-271 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KBFHEIFM_02372 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KBFHEIFM_02373 6.8e-294 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
KBFHEIFM_02374 1.59e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
KBFHEIFM_02375 2.25e-49 - - - S - - - Protein of unknown function (DUF4227)
KBFHEIFM_02376 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
KBFHEIFM_02377 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
KBFHEIFM_02378 3.08e-43 yqkK - - - - - - -
KBFHEIFM_02379 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
KBFHEIFM_02380 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
KBFHEIFM_02381 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
KBFHEIFM_02382 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
KBFHEIFM_02383 3.18e-77 ansR - - K - - - Transcriptional regulator
KBFHEIFM_02384 1.98e-278 yqxK - - L - - - DNA helicase
KBFHEIFM_02385 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
KBFHEIFM_02386 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
KBFHEIFM_02387 8.88e-216 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
KBFHEIFM_02388 6.61e-26 yqkE - - S - - - Protein of unknown function (DUF3886)
KBFHEIFM_02389 5.8e-222 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
KBFHEIFM_02390 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
KBFHEIFM_02391 3.57e-72 yqkB - - S - - - Belongs to the HesB IscA family
KBFHEIFM_02392 1.87e-247 yqkA - - K - - - GrpB protein
KBFHEIFM_02393 6.7e-73 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
KBFHEIFM_02394 5.46e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
KBFHEIFM_02395 9.27e-66 yqiX - - S - - - YolD-like protein
KBFHEIFM_02396 1.2e-303 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KBFHEIFM_02398 1.08e-289 yqjV - - G - - - Major Facilitator Superfamily
KBFHEIFM_02400 1.33e-95 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KBFHEIFM_02401 6.6e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
KBFHEIFM_02402 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
KBFHEIFM_02403 3.41e-185 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
KBFHEIFM_02404 3.27e-229 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
KBFHEIFM_02405 2.29e-188 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KBFHEIFM_02406 0.0 rocB - - E - - - arginine degradation protein
KBFHEIFM_02407 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
KBFHEIFM_02408 4.33e-185 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KBFHEIFM_02409 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
KBFHEIFM_02410 7.66e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KBFHEIFM_02411 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KBFHEIFM_02412 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KBFHEIFM_02413 7.8e-301 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KBFHEIFM_02414 1.77e-32 yqzJ - - - - - - -
KBFHEIFM_02415 3.36e-184 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KBFHEIFM_02416 4.68e-179 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
KBFHEIFM_02417 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
KBFHEIFM_02418 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KBFHEIFM_02419 1.9e-94 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
KBFHEIFM_02421 1.4e-127 yqjB - - S - - - protein conserved in bacteria
KBFHEIFM_02422 1.73e-221 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
KBFHEIFM_02423 1.28e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
KBFHEIFM_02424 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
KBFHEIFM_02425 1.43e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
KBFHEIFM_02426 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
KBFHEIFM_02427 4.23e-214 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KBFHEIFM_02428 5.12e-266 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
KBFHEIFM_02429 6.38e-195 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
KBFHEIFM_02430 1.13e-289 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KBFHEIFM_02431 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KBFHEIFM_02432 1.92e-238 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KBFHEIFM_02433 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KBFHEIFM_02434 3.39e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
KBFHEIFM_02435 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
KBFHEIFM_02436 3.02e-199 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
KBFHEIFM_02437 0.0 bkdR - - KT - - - Transcriptional regulator
KBFHEIFM_02438 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
KBFHEIFM_02439 1.77e-208 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KBFHEIFM_02440 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
KBFHEIFM_02441 9.18e-265 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
KBFHEIFM_02442 1.73e-268 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
KBFHEIFM_02443 6.9e-199 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
KBFHEIFM_02444 3.3e-280 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
KBFHEIFM_02445 7.42e-172 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
KBFHEIFM_02446 1.34e-137 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
KBFHEIFM_02447 4.74e-37 - - - - - - - -
KBFHEIFM_02448 1.63e-272 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
KBFHEIFM_02450 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
KBFHEIFM_02451 1.79e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
KBFHEIFM_02452 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
KBFHEIFM_02453 3.75e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
KBFHEIFM_02454 1.77e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
KBFHEIFM_02455 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KBFHEIFM_02456 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KBFHEIFM_02457 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KBFHEIFM_02458 3.55e-312 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KBFHEIFM_02459 1.07e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KBFHEIFM_02460 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KBFHEIFM_02461 1.65e-88 yqhY - - S - - - protein conserved in bacteria
KBFHEIFM_02462 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KBFHEIFM_02463 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KBFHEIFM_02464 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
KBFHEIFM_02465 8.86e-148 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
KBFHEIFM_02466 1.28e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
KBFHEIFM_02467 6.28e-256 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
KBFHEIFM_02468 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
KBFHEIFM_02469 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
KBFHEIFM_02470 1.63e-110 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
KBFHEIFM_02471 1.22e-218 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
KBFHEIFM_02472 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
KBFHEIFM_02473 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KBFHEIFM_02474 3.65e-250 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
KBFHEIFM_02475 1.17e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
KBFHEIFM_02476 1.14e-120 yqhR - - S - - - Conserved membrane protein YqhR
KBFHEIFM_02477 4.24e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
KBFHEIFM_02478 5.18e-81 yqhP - - - - - - -
KBFHEIFM_02479 5.75e-209 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
KBFHEIFM_02480 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
KBFHEIFM_02481 9.17e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
KBFHEIFM_02482 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
KBFHEIFM_02483 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KBFHEIFM_02484 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KBFHEIFM_02485 1.11e-260 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
KBFHEIFM_02486 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
KBFHEIFM_02487 9.14e-197 yqhG - - S - - - Bacterial protein YqhG of unknown function
KBFHEIFM_02488 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
KBFHEIFM_02489 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
KBFHEIFM_02490 9e-182 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
KBFHEIFM_02491 4.27e-97 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
KBFHEIFM_02492 1.8e-152 yqxM - - - ko:K19433 - ko00000 -
KBFHEIFM_02493 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
KBFHEIFM_02494 6.96e-37 yqzE - - S - - - YqzE-like protein
KBFHEIFM_02495 1.54e-56 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
KBFHEIFM_02496 1.18e-45 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
KBFHEIFM_02497 3.45e-76 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
KBFHEIFM_02498 3.12e-90 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
KBFHEIFM_02499 5.33e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
KBFHEIFM_02500 1.24e-218 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
KBFHEIFM_02501 2.59e-256 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KBFHEIFM_02503 3.73e-09 yhcV - - S - - - COG0517 FOG CBS domain
KBFHEIFM_02504 5.89e-231 yqxL - - P - - - Mg2 transporter protein
KBFHEIFM_02505 2.01e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
KBFHEIFM_02506 2.49e-192 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KBFHEIFM_02508 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
KBFHEIFM_02509 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
KBFHEIFM_02510 1.85e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
KBFHEIFM_02511 7.78e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
KBFHEIFM_02512 7.34e-66 yqgV - - S - - - Thiamine-binding protein
KBFHEIFM_02513 1.89e-256 yqgU - - - - - - -
KBFHEIFM_02514 4.84e-280 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
KBFHEIFM_02515 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
KBFHEIFM_02516 3.28e-230 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
KBFHEIFM_02517 9.15e-45 yqgQ - - S - - - Protein conserved in bacteria
KBFHEIFM_02518 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
KBFHEIFM_02519 3.38e-14 yqgO - - - - - - -
KBFHEIFM_02520 3.8e-135 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KBFHEIFM_02521 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
KBFHEIFM_02522 2.58e-253 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
KBFHEIFM_02524 3.42e-68 yqzD - - - - - - -
KBFHEIFM_02525 1.09e-93 yqzC - - S - - - YceG-like family
KBFHEIFM_02526 1.57e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KBFHEIFM_02527 9.78e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KBFHEIFM_02528 8.71e-201 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
KBFHEIFM_02529 7.11e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
KBFHEIFM_02530 5.26e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
KBFHEIFM_02531 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
KBFHEIFM_02532 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
KBFHEIFM_02533 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
KBFHEIFM_02534 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
KBFHEIFM_02535 2.74e-168 yqgB - - S - - - Protein of unknown function (DUF1189)
KBFHEIFM_02536 2.34e-62 yqfZ - - M ko:K06417 - ko00000 LysM domain
KBFHEIFM_02537 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KBFHEIFM_02538 4.8e-80 yqfX - - S - - - membrane
KBFHEIFM_02539 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
KBFHEIFM_02540 2.47e-106 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
KBFHEIFM_02541 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KBFHEIFM_02542 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
KBFHEIFM_02543 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KBFHEIFM_02544 6.32e-310 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KBFHEIFM_02545 5.25e-49 yqfQ - - S - - - YqfQ-like protein
KBFHEIFM_02546 8.66e-227 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KBFHEIFM_02547 8.5e-266 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KBFHEIFM_02548 1.98e-149 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
KBFHEIFM_02549 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
KBFHEIFM_02550 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KBFHEIFM_02551 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KBFHEIFM_02552 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
KBFHEIFM_02553 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KBFHEIFM_02554 3.29e-144 ccpN - - K - - - CBS domain
KBFHEIFM_02555 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
KBFHEIFM_02556 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
KBFHEIFM_02557 7.48e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
KBFHEIFM_02558 5.29e-27 - - - S - - - YqzL-like protein
KBFHEIFM_02559 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KBFHEIFM_02560 6.71e-93 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KBFHEIFM_02561 4.75e-80 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
KBFHEIFM_02562 8.68e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KBFHEIFM_02563 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
KBFHEIFM_02565 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
KBFHEIFM_02566 9.93e-241 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
KBFHEIFM_02567 2.07e-60 yqfC - - S - - - sporulation protein YqfC
KBFHEIFM_02568 1.37e-73 yqfB - - - - - - -
KBFHEIFM_02569 2.06e-190 yqfA - - S - - - UPF0365 protein
KBFHEIFM_02570 9.29e-291 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
KBFHEIFM_02571 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
KBFHEIFM_02572 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
KBFHEIFM_02573 4.02e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
KBFHEIFM_02574 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
KBFHEIFM_02575 1.38e-178 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KBFHEIFM_02576 4.63e-225 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
KBFHEIFM_02577 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KBFHEIFM_02578 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
KBFHEIFM_02579 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KBFHEIFM_02580 1.65e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KBFHEIFM_02581 1.68e-275 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
KBFHEIFM_02582 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KBFHEIFM_02583 7.06e-70 yqxA - - S - - - Protein of unknown function (DUF3679)
KBFHEIFM_02584 3.88e-283 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
KBFHEIFM_02585 3.42e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KBFHEIFM_02586 8.09e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
KBFHEIFM_02587 2.35e-243 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
KBFHEIFM_02588 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
KBFHEIFM_02589 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
KBFHEIFM_02590 3.85e-137 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
KBFHEIFM_02591 1.1e-188 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KBFHEIFM_02592 1.39e-178 yqeM - - Q - - - Methyltransferase
KBFHEIFM_02593 3.83e-79 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KBFHEIFM_02594 3.95e-132 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
KBFHEIFM_02595 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KBFHEIFM_02596 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
KBFHEIFM_02597 4.01e-199 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KBFHEIFM_02598 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KBFHEIFM_02599 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
KBFHEIFM_02601 2.24e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
KBFHEIFM_02602 7.45e-180 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
KBFHEIFM_02603 3.97e-136 yqeD - - S - - - SNARE associated Golgi protein
KBFHEIFM_02604 6.26e-216 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
KBFHEIFM_02605 9.38e-171 - - - - - - - -
KBFHEIFM_02606 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
KBFHEIFM_02607 7.53e-161 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KBFHEIFM_02608 2.72e-82 - - - K - - - BetI-type transcriptional repressor, C-terminal
KBFHEIFM_02609 5.34e-177 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
KBFHEIFM_02610 8.68e-120 - - - S - - - Tetratricopeptide repeat
KBFHEIFM_02613 1.3e-199 - - - S - - - Bacterial EndoU nuclease
KBFHEIFM_02614 5.46e-32 - - - S - - - SMI1-KNR4 cell-wall
KBFHEIFM_02615 2.55e-90 yokH - - G - - - SMI1 / KNR4 family
KBFHEIFM_02616 2.15e-69 - - - V - - - HNH endonuclease
KBFHEIFM_02617 6.57e-164 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
KBFHEIFM_02618 1.76e-33 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
KBFHEIFM_02619 8.88e-72 yqaS - - L - - - DNA packaging
KBFHEIFM_02620 0.000188 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
KBFHEIFM_02621 2.54e-36 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
KBFHEIFM_02622 5.15e-53 yqaQ - - L - - - Transposase
KBFHEIFM_02624 3.56e-08 - - - S - - - Bacillus cereus group antimicrobial protein
KBFHEIFM_02626 3.57e-49 yqaM - - L - - - IstB-like ATP binding protein
KBFHEIFM_02628 1.85e-204 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
KBFHEIFM_02629 1.31e-116 - - - K - - - Transcriptional regulator PadR-like family
KBFHEIFM_02630 1.5e-123 yqaC - - F - - - adenylate kinase activity
KBFHEIFM_02632 4.05e-130 xkdA - - E - - - IrrE N-terminal-like domain
KBFHEIFM_02633 1.42e-78 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KBFHEIFM_02634 2.15e-90 psiE - - S ko:K13256 - ko00000 Protein PsiE homolog
KBFHEIFM_02635 7.32e-306 yrkQ - - T - - - Histidine kinase
KBFHEIFM_02636 1.24e-164 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
KBFHEIFM_02637 7.53e-283 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
KBFHEIFM_02638 1.33e-134 yrkN - - K - - - Acetyltransferase (GNAT) family
KBFHEIFM_02639 5.71e-126 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
KBFHEIFM_02640 3.13e-104 - - - S - - - Protein of unknown function with HXXEE motif
KBFHEIFM_02641 1.21e-170 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
KBFHEIFM_02642 2.63e-48 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
KBFHEIFM_02643 4e-261 yrkH - - P - - - Rhodanese Homology Domain
KBFHEIFM_02644 0.000112 perX - - S - - - DsrE/DsrF-like family
KBFHEIFM_02645 1.61e-126 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
KBFHEIFM_02646 1.96e-108 yrkE - - O - - - DsrE/DsrF/DrsH-like family
KBFHEIFM_02647 4.38e-52 yrkD - - S - - - protein conserved in bacteria
KBFHEIFM_02648 4.45e-138 yrkC - - G - - - Cupin domain
KBFHEIFM_02649 1.39e-191 bltR - - K - - - helix_turn_helix, mercury resistance
KBFHEIFM_02650 6.23e-268 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
KBFHEIFM_02651 5.09e-107 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
KBFHEIFM_02652 2.15e-299 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
KBFHEIFM_02653 2.45e-23 - - - S - - - YrzO-like protein
KBFHEIFM_02654 8.49e-217 yrdR - - EG - - - EamA-like transporter family
KBFHEIFM_02655 2.42e-204 - - - K - - - Transcriptional regulator
KBFHEIFM_02656 3.02e-254 trkA - - P ko:K07222 - ko00000 Oxidoreductase
KBFHEIFM_02657 2.79e-202 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
KBFHEIFM_02658 2.05e-86 yodA - - S - - - tautomerase
KBFHEIFM_02659 2.43e-208 - - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
KBFHEIFM_02660 5.81e-291 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
KBFHEIFM_02661 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
KBFHEIFM_02662 9.34e-176 azlC - - E - - - AzlC protein
KBFHEIFM_02663 8.34e-104 bkdR - - K - - - helix_turn_helix ASNC type
KBFHEIFM_02664 2.73e-33 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
KBFHEIFM_02665 1.44e-294 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
KBFHEIFM_02667 2.11e-130 yrdC - - Q - - - Isochorismatase family
KBFHEIFM_02668 2.99e-71 - - - S - - - Protein of unknown function (DUF2568)
KBFHEIFM_02669 2.75e-116 yrdA - - S - - - DinB family
KBFHEIFM_02670 2.1e-212 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
KBFHEIFM_02671 3.79e-249 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
KBFHEIFM_02673 4.15e-189 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
KBFHEIFM_02674 5.63e-161 yrpD - - S - - - Domain of unknown function, YrpD
KBFHEIFM_02676 3.1e-168 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
KBFHEIFM_02677 2.14e-122 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KBFHEIFM_02678 6.96e-239 yrpG - - C - - - Aldo/keto reductase family
KBFHEIFM_02679 2.63e-286 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
KBFHEIFM_02680 5.13e-211 yraN - - K - - - Transcriptional regulator
KBFHEIFM_02681 1.4e-261 yraM - - S - - - PrpF protein
KBFHEIFM_02682 5.73e-202 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
KBFHEIFM_02683 1.45e-55 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KBFHEIFM_02684 3.31e-194 - - - S - - - Alpha beta hydrolase
KBFHEIFM_02685 6.61e-80 - - - T - - - sh3 domain protein
KBFHEIFM_02686 1.05e-81 - - - T - - - sh3 domain protein
KBFHEIFM_02687 1.56e-85 - - - E - - - Glyoxalase-like domain
KBFHEIFM_02688 1.2e-49 yraG - - - ko:K06440 - ko00000 -
KBFHEIFM_02689 7.91e-83 yraF - - M - - - Spore coat protein
KBFHEIFM_02690 2.14e-282 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KBFHEIFM_02691 2.49e-35 yraE - - - ko:K06440 - ko00000 -
KBFHEIFM_02692 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
KBFHEIFM_02693 3.17e-68 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
KBFHEIFM_02694 2.5e-39 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
KBFHEIFM_02695 5.86e-254 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
KBFHEIFM_02696 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
KBFHEIFM_02697 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
KBFHEIFM_02698 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
KBFHEIFM_02699 6.11e-168 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
KBFHEIFM_02700 7.63e-107 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
KBFHEIFM_02701 4.41e-96 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
KBFHEIFM_02702 0.0 levR - - K - - - PTS system fructose IIA component
KBFHEIFM_02703 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
KBFHEIFM_02704 5.63e-137 yrhP - - E - - - LysE type translocator
KBFHEIFM_02705 8.04e-192 yrhO - - K - - - Archaeal transcriptional regulator TrmB
KBFHEIFM_02706 5.77e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KBFHEIFM_02707 2.47e-191 rsiV - - S - - - Protein of unknown function (DUF3298)
KBFHEIFM_02708 0.0 oatA - - I - - - Acyltransferase family
KBFHEIFM_02709 4.43e-61 yrhK - - S - - - YrhK-like protein
KBFHEIFM_02710 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
KBFHEIFM_02711 9.22e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
KBFHEIFM_02712 1.05e-124 yrhH - - Q - - - methyltransferase
KBFHEIFM_02713 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
KBFHEIFM_02715 1.38e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
KBFHEIFM_02716 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
KBFHEIFM_02717 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
KBFHEIFM_02718 1.22e-102 yrhD - - S - - - Protein of unknown function (DUF1641)
KBFHEIFM_02719 6.93e-49 yrhC - - S - - - YrhC-like protein
KBFHEIFM_02720 8.55e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
KBFHEIFM_02721 1.66e-216 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
KBFHEIFM_02722 1.97e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KBFHEIFM_02723 3.44e-153 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
KBFHEIFM_02724 7.02e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
KBFHEIFM_02725 1.42e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
KBFHEIFM_02726 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
KBFHEIFM_02727 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KBFHEIFM_02728 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
KBFHEIFM_02729 1.88e-312 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
KBFHEIFM_02730 5.18e-221 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
KBFHEIFM_02731 1.4e-154 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
KBFHEIFM_02732 2.51e-240 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KBFHEIFM_02733 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
KBFHEIFM_02734 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KBFHEIFM_02735 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
KBFHEIFM_02736 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KBFHEIFM_02737 1.03e-240 yrrI - - S - - - AI-2E family transporter
KBFHEIFM_02738 1.28e-167 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
KBFHEIFM_02739 2.12e-186 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
KBFHEIFM_02740 3.78e-138 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KBFHEIFM_02741 3.77e-139 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KBFHEIFM_02742 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
KBFHEIFM_02743 8.4e-42 yrzR - - - - - - -
KBFHEIFM_02744 9.73e-106 yrrD - - S - - - protein conserved in bacteria
KBFHEIFM_02745 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KBFHEIFM_02746 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
KBFHEIFM_02747 1.19e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KBFHEIFM_02748 3.78e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
KBFHEIFM_02749 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
KBFHEIFM_02750 9.91e-303 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
KBFHEIFM_02751 1.09e-174 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
KBFHEIFM_02752 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KBFHEIFM_02753 7.37e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
KBFHEIFM_02755 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
KBFHEIFM_02756 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KBFHEIFM_02757 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KBFHEIFM_02758 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KBFHEIFM_02759 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
KBFHEIFM_02760 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
KBFHEIFM_02761 2.18e-112 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
KBFHEIFM_02762 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KBFHEIFM_02763 5.53e-65 yrzD - - S - - - Post-transcriptional regulator
KBFHEIFM_02764 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KBFHEIFM_02765 5.83e-143 yrbG - - S - - - membrane
KBFHEIFM_02766 4.89e-95 yrzE - - S - - - Protein of unknown function (DUF3792)
KBFHEIFM_02767 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
KBFHEIFM_02768 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KBFHEIFM_02769 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KBFHEIFM_02770 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
KBFHEIFM_02771 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KBFHEIFM_02772 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KBFHEIFM_02773 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
KBFHEIFM_02774 0.0 csbX - - EGP - - - the major facilitator superfamily
KBFHEIFM_02775 7.93e-248 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
KBFHEIFM_02776 3.17e-150 yrzF - - T - - - serine threonine protein kinase
KBFHEIFM_02778 3.62e-67 - - - S - - - Family of unknown function (DUF5412)
KBFHEIFM_02779 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
KBFHEIFM_02780 4.1e-163 yebC - - K - - - transcriptional regulatory protein
KBFHEIFM_02781 1.47e-69 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KBFHEIFM_02782 2.43e-217 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
KBFHEIFM_02783 7.94e-273 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KBFHEIFM_02784 6.71e-207 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
KBFHEIFM_02785 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
KBFHEIFM_02786 8.59e-293 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
KBFHEIFM_02787 5.02e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
KBFHEIFM_02788 1.43e-208 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
KBFHEIFM_02789 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
KBFHEIFM_02790 9.66e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KBFHEIFM_02791 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
KBFHEIFM_02792 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
KBFHEIFM_02793 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
KBFHEIFM_02794 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
KBFHEIFM_02795 3.74e-208 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
KBFHEIFM_02796 1.83e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
KBFHEIFM_02797 6.84e-185 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
KBFHEIFM_02798 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
KBFHEIFM_02799 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
KBFHEIFM_02800 1.91e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
KBFHEIFM_02801 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
KBFHEIFM_02802 3.07e-65 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
KBFHEIFM_02810 3.28e-136 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
KBFHEIFM_02811 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
KBFHEIFM_02812 4.02e-109 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
KBFHEIFM_02813 5.98e-168 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
KBFHEIFM_02814 8.03e-71 - - - S - - - Pfam:Phage_holin_4_1
KBFHEIFM_02815 1.14e-24 - - - - - - - -
KBFHEIFM_02818 1.52e-64 - - - S - - - Domain of unknown function (DUF2479)
KBFHEIFM_02821 5.14e-62 - - - - - - - -
KBFHEIFM_02822 3.16e-274 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
KBFHEIFM_02823 4.84e-135 - - - S - - - Phage tail protein
KBFHEIFM_02824 0.0 - - - D - - - phage tail tape measure protein
KBFHEIFM_02827 3.23e-101 - - - S - - - Phage tail tube protein
KBFHEIFM_02829 1.19e-66 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
KBFHEIFM_02830 6.1e-51 - - - S - - - Phage head-tail joining protein
KBFHEIFM_02831 8.77e-54 - - - S - - - Phage gp6-like head-tail connector protein
KBFHEIFM_02832 1.83e-35 - - - - - - - -
KBFHEIFM_02833 1.94e-204 - - - S - - - capsid protein
KBFHEIFM_02834 5.33e-102 - - - S - - - peptidase activity
KBFHEIFM_02835 1.93e-220 - - - S - - - Phage portal protein
KBFHEIFM_02836 0.0 - - - S - - - Terminase
KBFHEIFM_02837 2.11e-101 - - - L - - - phage terminase small subunit
KBFHEIFM_02838 1.69e-66 - - - V ko:K07451 - ko00000,ko01000,ko02048 HNH endonuclease
KBFHEIFM_02841 3.1e-27 - - - N - - - PFAM YcfA family protein
KBFHEIFM_02842 1.15e-85 - - - S - - - regulation of transcription, DNA-dependent
KBFHEIFM_02843 4.97e-60 - - - - - - - -
KBFHEIFM_02846 2.05e-104 - - - - - - - -
KBFHEIFM_02847 3.14e-121 - - - S - - - nuclease activity
KBFHEIFM_02848 6.74e-86 - - - - - - - -
KBFHEIFM_02849 0.0 - - - S - - - hydrolase activity
KBFHEIFM_02850 3.5e-97 - - - S - - - Protein of unknown function (DUF669)
KBFHEIFM_02852 1.3e-211 - - - D - - - AAA domain
KBFHEIFM_02853 7.62e-120 - - - S - - - DNA protection
KBFHEIFM_02855 4.38e-29 - - - S - - - Uncharacterized protein YqaH
KBFHEIFM_02858 1.62e-12 - - - K - - - helix-turn-helix
KBFHEIFM_02859 8.51e-82 - - - S - - - sequence-specific DNA binding
KBFHEIFM_02860 4.72e-92 - - - S - - - Pfam:Peptidase_M78
KBFHEIFM_02861 5.65e-288 - - - S - - - Recombinase
KBFHEIFM_02862 3.36e-87 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
KBFHEIFM_02863 1e-131 maf - - D ko:K06287 - ko00000 septum formation protein Maf
KBFHEIFM_02864 1.01e-209 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
KBFHEIFM_02865 1.28e-108 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
KBFHEIFM_02866 3.19e-315 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
KBFHEIFM_02867 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KBFHEIFM_02868 1.53e-35 - - - - - - - -
KBFHEIFM_02869 1.96e-251 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KBFHEIFM_02870 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
KBFHEIFM_02871 1.44e-311 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
KBFHEIFM_02872 3.7e-233 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
KBFHEIFM_02873 7.14e-184 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
KBFHEIFM_02874 7.63e-221 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
KBFHEIFM_02875 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
KBFHEIFM_02876 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KBFHEIFM_02877 6.77e-116 ysxD - - - - - - -
KBFHEIFM_02878 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
KBFHEIFM_02879 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KBFHEIFM_02880 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
KBFHEIFM_02881 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KBFHEIFM_02882 2.96e-285 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KBFHEIFM_02883 1.11e-239 ysoA - - H - - - Tetratricopeptide repeat
KBFHEIFM_02884 1.26e-148 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KBFHEIFM_02885 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KBFHEIFM_02886 2.13e-255 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KBFHEIFM_02887 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KBFHEIFM_02888 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KBFHEIFM_02889 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
KBFHEIFM_02890 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
KBFHEIFM_02891 8.46e-101 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
KBFHEIFM_02892 4.1e-184 ysnF - - S - - - protein conserved in bacteria
KBFHEIFM_02894 4.05e-119 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
KBFHEIFM_02895 3.05e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KBFHEIFM_02896 3.53e-171 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KBFHEIFM_02897 1.62e-255 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
KBFHEIFM_02898 2.14e-192 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
KBFHEIFM_02899 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
KBFHEIFM_02900 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
KBFHEIFM_02901 2.18e-101 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
KBFHEIFM_02902 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
KBFHEIFM_02903 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
KBFHEIFM_02904 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
KBFHEIFM_02905 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
KBFHEIFM_02906 4.83e-276 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
KBFHEIFM_02907 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KBFHEIFM_02908 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
KBFHEIFM_02909 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
KBFHEIFM_02910 8.65e-228 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
KBFHEIFM_02911 1.28e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
KBFHEIFM_02912 3.12e-176 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
KBFHEIFM_02913 1.21e-130 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
KBFHEIFM_02914 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KBFHEIFM_02915 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
KBFHEIFM_02916 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KBFHEIFM_02917 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
KBFHEIFM_02918 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
KBFHEIFM_02919 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KBFHEIFM_02920 2.84e-213 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KBFHEIFM_02921 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KBFHEIFM_02922 1.81e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KBFHEIFM_02923 3.13e-171 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KBFHEIFM_02924 4.37e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
KBFHEIFM_02925 3.06e-261 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
KBFHEIFM_02926 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
KBFHEIFM_02927 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
KBFHEIFM_02928 2.94e-69 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
KBFHEIFM_02929 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
KBFHEIFM_02930 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
KBFHEIFM_02931 6.34e-192 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
KBFHEIFM_02932 3.22e-217 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
KBFHEIFM_02933 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
KBFHEIFM_02934 3.05e-281 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
KBFHEIFM_02935 6.06e-187 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
KBFHEIFM_02936 6.93e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
KBFHEIFM_02937 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
KBFHEIFM_02938 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
KBFHEIFM_02939 4.21e-243 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
KBFHEIFM_02940 4.35e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
KBFHEIFM_02941 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
KBFHEIFM_02942 1.27e-59 ysdA - - S - - - Membrane
KBFHEIFM_02943 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KBFHEIFM_02944 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
KBFHEIFM_02945 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KBFHEIFM_02947 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KBFHEIFM_02948 8.47e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KBFHEIFM_02949 3.95e-166 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
KBFHEIFM_02950 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KBFHEIFM_02951 1.98e-189 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
KBFHEIFM_02952 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KBFHEIFM_02954 3.46e-205 ytxC - - S - - - YtxC-like family
KBFHEIFM_02955 2.8e-143 ytxB - - S - - - SNARE associated Golgi protein
KBFHEIFM_02956 1.22e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
KBFHEIFM_02957 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
KBFHEIFM_02958 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KBFHEIFM_02959 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KBFHEIFM_02960 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KBFHEIFM_02961 9.85e-88 ytcD - - K - - - Transcriptional regulator
KBFHEIFM_02962 1.12e-254 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
KBFHEIFM_02963 4.54e-205 ytbE - - S - - - reductase
KBFHEIFM_02964 3.29e-125 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KBFHEIFM_02965 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
KBFHEIFM_02966 1.92e-200 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KBFHEIFM_02967 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KBFHEIFM_02968 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
KBFHEIFM_02969 1.62e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KBFHEIFM_02970 1.04e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
KBFHEIFM_02971 2.28e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
KBFHEIFM_02972 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
KBFHEIFM_02973 2.69e-94 ytwI - - S - - - membrane
KBFHEIFM_02974 2.73e-245 ytvI - - S - - - sporulation integral membrane protein YtvI
KBFHEIFM_02975 4.68e-82 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
KBFHEIFM_02976 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
KBFHEIFM_02977 1.62e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KBFHEIFM_02978 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KBFHEIFM_02979 2.17e-208 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KBFHEIFM_02980 8.53e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
KBFHEIFM_02981 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
KBFHEIFM_02982 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
KBFHEIFM_02983 5.12e-112 ytrI - - - - - - -
KBFHEIFM_02984 1.15e-39 - - - - - - - -
KBFHEIFM_02985 5.88e-229 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
KBFHEIFM_02986 2.15e-63 ytpI - - S - - - YtpI-like protein
KBFHEIFM_02987 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
KBFHEIFM_02988 6.14e-204 ytnM - - S ko:K07090 - ko00000 membrane transporter protein
KBFHEIFM_02989 5.28e-300 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
KBFHEIFM_02990 1.69e-166 - 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin kinase
KBFHEIFM_02991 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KBFHEIFM_02992 5.26e-63 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
KBFHEIFM_02993 1.52e-237 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KBFHEIFM_02994 6.61e-183 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
KBFHEIFM_02995 4.76e-155 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KBFHEIFM_02996 1.66e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KBFHEIFM_02997 1.34e-192 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
KBFHEIFM_02998 3.18e-195 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
KBFHEIFM_02999 8.39e-130 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
KBFHEIFM_03000 1.67e-221 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
KBFHEIFM_03001 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
KBFHEIFM_03002 1.98e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KBFHEIFM_03004 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
KBFHEIFM_03005 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
KBFHEIFM_03006 2.33e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
KBFHEIFM_03007 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KBFHEIFM_03008 3.78e-224 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
KBFHEIFM_03009 1.12e-115 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KBFHEIFM_03010 2.24e-96 ytfJ - - S - - - Sporulation protein YtfJ
KBFHEIFM_03011 5.63e-147 ytfI - - S - - - Protein of unknown function (DUF2953)
KBFHEIFM_03012 4.08e-112 yteJ - - S - - - RDD family
KBFHEIFM_03013 3.96e-229 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
KBFHEIFM_03014 2.92e-190 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KBFHEIFM_03015 0.0 ytcJ - - S - - - amidohydrolase
KBFHEIFM_03016 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KBFHEIFM_03017 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
KBFHEIFM_03018 6.26e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KBFHEIFM_03019 1.22e-269 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
KBFHEIFM_03020 8.23e-305 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
KBFHEIFM_03021 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KBFHEIFM_03022 3.73e-198 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
KBFHEIFM_03023 1.2e-141 yttP - - K - - - Transcriptional regulator
KBFHEIFM_03024 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
KBFHEIFM_03025 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
KBFHEIFM_03026 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KBFHEIFM_03028 6.47e-304 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KBFHEIFM_03029 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KBFHEIFM_03030 2.43e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
KBFHEIFM_03031 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
KBFHEIFM_03032 3.09e-291 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
KBFHEIFM_03033 1.15e-157 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
KBFHEIFM_03034 1.96e-186 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
KBFHEIFM_03035 1.7e-234 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
KBFHEIFM_03036 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
KBFHEIFM_03037 1.57e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
KBFHEIFM_03038 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
KBFHEIFM_03039 3.8e-26 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KBFHEIFM_03040 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
KBFHEIFM_03041 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
KBFHEIFM_03042 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KBFHEIFM_03043 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
KBFHEIFM_03044 3.17e-75 ytpP - - CO - - - Thioredoxin
KBFHEIFM_03045 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
KBFHEIFM_03046 3.71e-261 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
KBFHEIFM_03047 6.75e-67 ytzB - - S - - - small secreted protein
KBFHEIFM_03048 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
KBFHEIFM_03049 2.15e-190 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
KBFHEIFM_03050 2.52e-155 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KBFHEIFM_03051 9.51e-61 ytzH - - S - - - YtzH-like protein
KBFHEIFM_03052 3.02e-192 ytmP - - M - - - Phosphotransferase
KBFHEIFM_03053 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
KBFHEIFM_03054 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
KBFHEIFM_03055 8.15e-211 ytlQ - - - - - - -
KBFHEIFM_03056 5.22e-131 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KBFHEIFM_03057 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
KBFHEIFM_03058 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
KBFHEIFM_03059 2.86e-287 pbuO - - S ko:K06901 - ko00000,ko02000 permease
KBFHEIFM_03060 3.51e-255 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
KBFHEIFM_03061 5.66e-168 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KBFHEIFM_03062 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
KBFHEIFM_03063 7.43e-170 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
KBFHEIFM_03064 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KBFHEIFM_03065 6.99e-294 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
KBFHEIFM_03066 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
KBFHEIFM_03067 2.14e-36 yteV - - S - - - Sporulation protein Cse60
KBFHEIFM_03068 1.09e-149 yteU - - S - - - Integral membrane protein
KBFHEIFM_03069 0.0 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
KBFHEIFM_03070 2.76e-93 yteS - - G - - - transport
KBFHEIFM_03071 1.96e-277 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
KBFHEIFM_03072 1.31e-220 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
KBFHEIFM_03073 0.0 ytdP - - K - - - Transcriptional regulator
KBFHEIFM_03074 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
KBFHEIFM_03075 6.19e-193 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
KBFHEIFM_03076 2.21e-178 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
KBFHEIFM_03077 6.39e-279 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
KBFHEIFM_03078 7.57e-243 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KBFHEIFM_03079 2.68e-159 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KBFHEIFM_03080 3.28e-278 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KBFHEIFM_03081 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
KBFHEIFM_03082 7.82e-180 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
KBFHEIFM_03083 1.95e-220 - - - S - - - Acetyl xylan esterase (AXE1)
KBFHEIFM_03084 1.53e-242 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
KBFHEIFM_03085 6.33e-313 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KBFHEIFM_03086 1.66e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KBFHEIFM_03087 3.63e-184 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
KBFHEIFM_03088 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
KBFHEIFM_03089 1.22e-68 ytwF - - P - - - Sulfurtransferase
KBFHEIFM_03090 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
KBFHEIFM_03091 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
KBFHEIFM_03092 5.43e-183 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
KBFHEIFM_03093 1.21e-268 yttB - - EGP - - - Major facilitator superfamily
KBFHEIFM_03094 5.75e-78 yttA - - S - - - Pfam Transposase IS66
KBFHEIFM_03095 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
KBFHEIFM_03096 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
KBFHEIFM_03097 1.58e-239 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
KBFHEIFM_03098 1.77e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KBFHEIFM_03099 8.41e-298 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
KBFHEIFM_03100 1.02e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KBFHEIFM_03101 1.94e-192 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
KBFHEIFM_03102 3.35e-222 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
KBFHEIFM_03103 1.03e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KBFHEIFM_03104 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
KBFHEIFM_03106 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
KBFHEIFM_03107 4.06e-245 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
KBFHEIFM_03108 6.76e-137 ytqB - - J - - - Putative rRNA methylase
KBFHEIFM_03109 4.81e-276 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
KBFHEIFM_03110 2.33e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
KBFHEIFM_03111 8.35e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KBFHEIFM_03112 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
KBFHEIFM_03113 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
KBFHEIFM_03114 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KBFHEIFM_03115 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KBFHEIFM_03116 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
KBFHEIFM_03117 1.11e-189 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
KBFHEIFM_03118 1.13e-241 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KBFHEIFM_03119 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KBFHEIFM_03120 1.09e-182 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KBFHEIFM_03121 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
KBFHEIFM_03122 1.59e-81 ytkC - - S - - - Bacteriophage holin family
KBFHEIFM_03123 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
KBFHEIFM_03125 6.79e-95 ytkA - - S - - - YtkA-like
KBFHEIFM_03126 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KBFHEIFM_03127 8.96e-134 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
KBFHEIFM_03128 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
KBFHEIFM_03129 1.03e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
KBFHEIFM_03130 2.83e-239 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
KBFHEIFM_03131 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
KBFHEIFM_03132 9.65e-194 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
KBFHEIFM_03133 2.6e-296 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KBFHEIFM_03134 1.68e-176 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KBFHEIFM_03135 2.65e-217 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
KBFHEIFM_03136 7.07e-273 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
KBFHEIFM_03137 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KBFHEIFM_03138 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KBFHEIFM_03139 1.15e-195 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
KBFHEIFM_03140 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KBFHEIFM_03141 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
KBFHEIFM_03142 1.75e-168 yteA - - T - - - COG1734 DnaK suppressor protein
KBFHEIFM_03143 1.7e-196 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
KBFHEIFM_03144 3.93e-308 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KBFHEIFM_03145 2.48e-227 ytcB - - M - - - NAD-dependent epimerase dehydratase
KBFHEIFM_03146 3.7e-300 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
KBFHEIFM_03148 1.7e-263 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
KBFHEIFM_03149 3.53e-276 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
KBFHEIFM_03150 1.06e-259 cotI - - S ko:K06331 - ko00000 Spore coat protein
KBFHEIFM_03151 7.86e-71 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
KBFHEIFM_03152 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KBFHEIFM_03153 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
KBFHEIFM_03154 1.58e-239 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
KBFHEIFM_03155 2.84e-263 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KBFHEIFM_03156 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KBFHEIFM_03178 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
KBFHEIFM_03179 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
KBFHEIFM_03180 3.31e-120 - - - M - - - FR47-like protein
KBFHEIFM_03181 9.14e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
KBFHEIFM_03182 8e-108 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
KBFHEIFM_03183 1.95e-109 yuaE - - S - - - DinB superfamily
KBFHEIFM_03184 3.5e-138 yuaD - - - - - - -
KBFHEIFM_03185 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
KBFHEIFM_03186 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KBFHEIFM_03187 2.9e-122 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
KBFHEIFM_03188 5.83e-118 yuaB - - - - - - -
KBFHEIFM_03189 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
KBFHEIFM_03190 5.08e-299 - - - P ko:K03498 - ko00000,ko02000 Potassium
KBFHEIFM_03191 3.31e-52 yubF - - S - - - yiaA/B two helix domain
KBFHEIFM_03192 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KBFHEIFM_03193 0.0 yubD - - P - - - Major Facilitator Superfamily
KBFHEIFM_03194 3.95e-113 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
KBFHEIFM_03196 1.69e-26 - - - - - - - -
KBFHEIFM_03199 4.51e-34 - - - K - - - Helix-turn-helix domain
KBFHEIFM_03202 9.79e-139 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
KBFHEIFM_03203 2.63e-40 xhlB - - S - - - SPP1 phage holin
KBFHEIFM_03204 1.56e-36 xhlA - - S - - - Haemolysin XhlA
KBFHEIFM_03209 2.42e-273 - - - S - - - peptidoglycan catabolic process
KBFHEIFM_03210 8.87e-07 - - - S - - - phage tail component
KBFHEIFM_03211 3.83e-171 - - - - - - - -
KBFHEIFM_03212 2.08e-36 - - - S - - - Phage tail assembly chaperone protein, TAC
KBFHEIFM_03213 1.39e-41 - - - N - - - Bacterial Ig-like domain 2
KBFHEIFM_03214 4e-38 - - - S - - - Protein of unknown function (DUF3168)
KBFHEIFM_03215 1.74e-47 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
KBFHEIFM_03216 2.16e-35 - - - S - - - Phage head-tail joining protein
KBFHEIFM_03217 3.86e-39 - - - S - - - Phage gp6-like head-tail connector protein
KBFHEIFM_03220 4.26e-182 - - - S - - - Phage capsid family
KBFHEIFM_03221 2.07e-80 - - - S - - - Domain of unknown function (DUF4355)
KBFHEIFM_03224 4.75e-113 - - - S - - - Phage Mu protein F like protein
KBFHEIFM_03225 5.97e-257 - - - S - - - Phage portal protein, SPP1 Gp6-like
KBFHEIFM_03226 1.34e-281 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
KBFHEIFM_03227 2.12e-128 yqaS - - L - - - DNA packaging
KBFHEIFM_03229 7.39e-53 - - - L - - - Transposase
KBFHEIFM_03240 3.09e-06 - - - S - - - YopX protein
KBFHEIFM_03241 2.95e-64 - - - S - - - dUTPase
KBFHEIFM_03245 4.36e-35 yqaO - - S - - - Phage-like element PBSX protein XtrA
KBFHEIFM_03247 6.38e-71 - - - S - - - Protein of unknown function (DUF1064)
KBFHEIFM_03249 7.71e-16 - - - S - - - YopX protein
KBFHEIFM_03251 4.27e-102 yqaM - - L - - - IstB-like ATP binding protein
KBFHEIFM_03252 8.98e-63 yqaL - - L - - - DnaD domain protein
KBFHEIFM_03253 3.61e-171 recT - - L ko:K07455 - ko00000,ko03400 RecT family
KBFHEIFM_03254 9.35e-194 yqaJ - - L - - - YqaJ-like viral recombinase domain
KBFHEIFM_03260 4.76e-105 - - - - - - - -
KBFHEIFM_03261 7.88e-65 - - - S - - - DNA binding
KBFHEIFM_03262 5.71e-22 - - - S - - - Helix-turn-helix domain
KBFHEIFM_03263 2.19e-05 - - - K - - - Helix-turn-helix domain
KBFHEIFM_03264 2.02e-21 - - - K - - - Helix-turn-helix XRE-family like proteins
KBFHEIFM_03265 4.75e-14 - - - S - - - Short C-terminal domain
KBFHEIFM_03267 3.42e-64 xkdA - - E - - - IrrE N-terminal-like domain
KBFHEIFM_03268 1.67e-209 int7 - - L - - - Belongs to the 'phage' integrase family
KBFHEIFM_03270 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KBFHEIFM_03271 1.73e-252 yubA - - S - - - transporter activity
KBFHEIFM_03272 9.11e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
KBFHEIFM_03273 1.96e-316 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
KBFHEIFM_03274 8.22e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
KBFHEIFM_03275 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
KBFHEIFM_03276 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
KBFHEIFM_03277 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
KBFHEIFM_03278 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KBFHEIFM_03279 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KBFHEIFM_03280 2.29e-295 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KBFHEIFM_03281 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KBFHEIFM_03282 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
KBFHEIFM_03283 1.44e-47 - - - - - - - -
KBFHEIFM_03284 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
KBFHEIFM_03285 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
KBFHEIFM_03286 2.52e-300 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
KBFHEIFM_03287 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
KBFHEIFM_03288 2.16e-48 - - - - - - - -
KBFHEIFM_03289 2.12e-70 mstX - - S - - - Membrane-integrating protein Mistic
KBFHEIFM_03290 3.56e-233 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
KBFHEIFM_03291 4.22e-95 yugN - - S - - - YugN-like family
KBFHEIFM_03293 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
KBFHEIFM_03294 2.64e-289 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
KBFHEIFM_03295 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
KBFHEIFM_03296 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
KBFHEIFM_03297 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
KBFHEIFM_03298 5.43e-255 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
KBFHEIFM_03299 6.74e-112 alaR - - K - - - Transcriptional regulator
KBFHEIFM_03300 9.89e-201 yugF - - I - - - Hydrolase
KBFHEIFM_03301 8.84e-52 yugE - - S - - - Domain of unknown function (DUF1871)
KBFHEIFM_03302 4.53e-284 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KBFHEIFM_03303 8.71e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KBFHEIFM_03304 6.12e-92 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
KBFHEIFM_03305 8.49e-150 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
KBFHEIFM_03307 1.08e-242 yuxJ - - EGP - - - Major facilitator superfamily
KBFHEIFM_03308 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
KBFHEIFM_03309 1.92e-97 yuxK - - S - - - protein conserved in bacteria
KBFHEIFM_03310 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
KBFHEIFM_03311 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
KBFHEIFM_03312 3.26e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
KBFHEIFM_03313 9.13e-247 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
KBFHEIFM_03314 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KBFHEIFM_03315 6.39e-237 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KBFHEIFM_03316 1.71e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KBFHEIFM_03317 7.99e-309 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
KBFHEIFM_03318 1.73e-22 - - - - - - - -
KBFHEIFM_03319 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
KBFHEIFM_03320 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KBFHEIFM_03321 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KBFHEIFM_03322 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KBFHEIFM_03323 2.47e-101 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KBFHEIFM_03324 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KBFHEIFM_03325 5.97e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
KBFHEIFM_03326 7.81e-83 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
KBFHEIFM_03327 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KBFHEIFM_03328 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KBFHEIFM_03330 1.89e-164 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
KBFHEIFM_03331 6.29e-10 - - - S - - - DegQ (SacQ) family
KBFHEIFM_03332 8.73e-09 yuzC - - - - - - -
KBFHEIFM_03333 2.92e-298 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
KBFHEIFM_03334 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KBFHEIFM_03335 2.69e-133 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
KBFHEIFM_03336 2.19e-87 - - - S - - - Protein of unknown function (DUF1694)
KBFHEIFM_03337 3.17e-50 yueH - - S - - - YueH-like protein
KBFHEIFM_03338 7.15e-43 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
KBFHEIFM_03339 1.58e-243 yueF - - S - - - transporter activity
KBFHEIFM_03340 9.01e-90 - - - S - - - Protein of unknown function (DUF2283)
KBFHEIFM_03341 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
KBFHEIFM_03342 1.91e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
KBFHEIFM_03343 2.9e-169 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KBFHEIFM_03344 5.1e-96 yueC - - S - - - Family of unknown function (DUF5383)
KBFHEIFM_03345 0.0 yueB - - S - - - type VII secretion protein EsaA
KBFHEIFM_03346 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
KBFHEIFM_03347 4.28e-271 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
KBFHEIFM_03348 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
KBFHEIFM_03349 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
KBFHEIFM_03350 1.03e-292 yukF - - QT - - - Transcriptional regulator
KBFHEIFM_03351 6.66e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
KBFHEIFM_03352 1.2e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
KBFHEIFM_03353 4.08e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
KBFHEIFM_03354 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KBFHEIFM_03355 3.83e-229 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
KBFHEIFM_03356 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
KBFHEIFM_03357 4.24e-290 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
KBFHEIFM_03358 5.83e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
KBFHEIFM_03359 8.94e-213 eSD - - S ko:K07017 - ko00000 Putative esterase
KBFHEIFM_03360 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
KBFHEIFM_03361 2.39e-124 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
KBFHEIFM_03362 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
KBFHEIFM_03363 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KBFHEIFM_03364 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
KBFHEIFM_03365 2.69e-150 yuiC - - S - - - protein conserved in bacteria
KBFHEIFM_03366 9.78e-47 yuiB - - S - - - Putative membrane protein
KBFHEIFM_03367 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
KBFHEIFM_03368 5.51e-239 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
KBFHEIFM_03370 6.4e-235 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KBFHEIFM_03371 1.16e-148 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
KBFHEIFM_03372 6.88e-116 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KBFHEIFM_03373 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
KBFHEIFM_03374 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KBFHEIFM_03375 2.54e-269 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KBFHEIFM_03376 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
KBFHEIFM_03377 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
KBFHEIFM_03378 1.29e-72 yuzD - - S - - - protein conserved in bacteria
KBFHEIFM_03379 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
KBFHEIFM_03380 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
KBFHEIFM_03381 2.57e-221 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KBFHEIFM_03382 8.01e-252 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KBFHEIFM_03383 9.64e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
KBFHEIFM_03384 5.41e-254 yutH - - S - - - Spore coat protein
KBFHEIFM_03385 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
KBFHEIFM_03386 3.69e-183 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KBFHEIFM_03387 2.38e-99 yutE - - S - - - Protein of unknown function DUF86
KBFHEIFM_03388 3.2e-63 yutD - - S - - - protein conserved in bacteria
KBFHEIFM_03389 1.34e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KBFHEIFM_03390 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KBFHEIFM_03391 2.66e-252 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
KBFHEIFM_03392 3.49e-169 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
KBFHEIFM_03393 1.39e-64 yunC - - S - - - Domain of unknown function (DUF1805)
KBFHEIFM_03394 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KBFHEIFM_03395 1.79e-178 yunE - - S ko:K07090 - ko00000 membrane transporter protein
KBFHEIFM_03396 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
KBFHEIFM_03397 3.06e-79 yunG - - - - - - -
KBFHEIFM_03398 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
KBFHEIFM_03399 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
KBFHEIFM_03400 8.96e-293 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
KBFHEIFM_03401 2.24e-283 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
KBFHEIFM_03402 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
KBFHEIFM_03403 2.09e-72 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
KBFHEIFM_03404 4.18e-123 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
KBFHEIFM_03405 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
KBFHEIFM_03406 4.27e-188 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
KBFHEIFM_03407 1.2e-140 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
KBFHEIFM_03408 1.24e-234 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KBFHEIFM_03410 1.21e-305 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
KBFHEIFM_03411 1.44e-295 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
KBFHEIFM_03412 7.63e-217 bsn - - L - - - Ribonuclease
KBFHEIFM_03413 2.95e-263 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KBFHEIFM_03414 8.71e-175 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
KBFHEIFM_03415 7.86e-208 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
KBFHEIFM_03416 1.94e-216 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
KBFHEIFM_03417 3.54e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KBFHEIFM_03418 2.87e-307 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
KBFHEIFM_03419 5.27e-235 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
KBFHEIFM_03420 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
KBFHEIFM_03421 7.54e-264 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
KBFHEIFM_03423 1.94e-55 - - - - - - - -
KBFHEIFM_03424 1.24e-86 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KBFHEIFM_03425 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
KBFHEIFM_03426 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
KBFHEIFM_03427 5.67e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KBFHEIFM_03428 2.04e-310 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
KBFHEIFM_03429 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KBFHEIFM_03430 5.44e-81 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KBFHEIFM_03431 1.01e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
KBFHEIFM_03432 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
KBFHEIFM_03433 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KBFHEIFM_03434 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
KBFHEIFM_03435 2e-73 yusE - - CO - - - Thioredoxin
KBFHEIFM_03436 7.62e-97 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
KBFHEIFM_03437 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
KBFHEIFM_03438 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
KBFHEIFM_03439 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
KBFHEIFM_03440 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
KBFHEIFM_03441 1.34e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
KBFHEIFM_03442 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
KBFHEIFM_03443 1.11e-13 - - - S - - - YuzL-like protein
KBFHEIFM_03444 1.21e-211 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
KBFHEIFM_03445 2.23e-54 - - - - - - - -
KBFHEIFM_03446 8.66e-70 yusN - - M - - - Coat F domain
KBFHEIFM_03447 5.22e-97 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
KBFHEIFM_03448 0.0 yusP - - P - - - Major facilitator superfamily
KBFHEIFM_03449 1.7e-84 yusQ - - S - - - Tautomerase enzyme
KBFHEIFM_03450 7.05e-138 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
KBFHEIFM_03451 4.87e-203 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
KBFHEIFM_03452 3.66e-64 yusU - - S - - - Protein of unknown function (DUF2573)
KBFHEIFM_03453 1.06e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KBFHEIFM_03454 3.48e-88 - - - S - - - YusW-like protein
KBFHEIFM_03455 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
KBFHEIFM_03456 4.49e-196 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KBFHEIFM_03457 8.76e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
KBFHEIFM_03458 2.17e-302 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KBFHEIFM_03459 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KBFHEIFM_03460 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KBFHEIFM_03461 3.06e-204 yuxN - - K - - - Transcriptional regulator
KBFHEIFM_03462 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KBFHEIFM_03463 4.48e-34 - - - S - - - Protein of unknown function (DUF3970)
KBFHEIFM_03464 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
KBFHEIFM_03465 7.95e-251 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
KBFHEIFM_03466 1.02e-241 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
KBFHEIFM_03467 2.69e-140 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KBFHEIFM_03468 5.98e-235 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KBFHEIFM_03469 3.12e-163 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
KBFHEIFM_03470 1.57e-169 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
KBFHEIFM_03471 2.44e-143 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
KBFHEIFM_03472 1.07e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
KBFHEIFM_03473 4.58e-288 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
KBFHEIFM_03474 4.56e-130 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
KBFHEIFM_03475 1.22e-307 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
KBFHEIFM_03476 7.4e-234 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KBFHEIFM_03477 5.15e-219 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
KBFHEIFM_03478 6.08e-181 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KBFHEIFM_03479 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
KBFHEIFM_03480 0.0 yvrG - - T - - - Histidine kinase
KBFHEIFM_03481 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KBFHEIFM_03482 6.16e-33 - - - - - - - -
KBFHEIFM_03483 5.77e-127 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
KBFHEIFM_03484 1.41e-25 - - - S - - - YvrJ protein family
KBFHEIFM_03485 9.23e-292 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
KBFHEIFM_03486 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
KBFHEIFM_03487 1.17e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
KBFHEIFM_03488 1.62e-159 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KBFHEIFM_03489 2.31e-227 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
KBFHEIFM_03490 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KBFHEIFM_03491 4.78e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KBFHEIFM_03492 1.48e-237 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KBFHEIFM_03493 7.37e-224 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KBFHEIFM_03494 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
KBFHEIFM_03495 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
KBFHEIFM_03496 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
KBFHEIFM_03497 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
KBFHEIFM_03498 2.54e-214 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
KBFHEIFM_03499 2.11e-175 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
KBFHEIFM_03500 1.74e-153 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
KBFHEIFM_03501 1.03e-199 yvgN - - S - - - reductase
KBFHEIFM_03502 1.88e-111 yvgO - - - - - - -
KBFHEIFM_03503 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
KBFHEIFM_03504 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
KBFHEIFM_03505 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KBFHEIFM_03506 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
KBFHEIFM_03508 2.34e-139 yvgT - - S - - - membrane
KBFHEIFM_03509 1.99e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
KBFHEIFM_03510 3.45e-137 bdbD - - O - - - Thioredoxin
KBFHEIFM_03511 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
KBFHEIFM_03512 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
KBFHEIFM_03513 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
KBFHEIFM_03514 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
KBFHEIFM_03515 1.4e-247 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
KBFHEIFM_03516 3.59e-154 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KBFHEIFM_03517 0.0 - - - S - - - Fusaric acid resistance protein-like
KBFHEIFM_03518 2.36e-96 yvaD - - S - - - Family of unknown function (DUF5360)
KBFHEIFM_03519 2.04e-70 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
KBFHEIFM_03520 8.55e-129 - - - K - - - Bacterial regulatory proteins, tetR family
KBFHEIFM_03521 3.96e-182 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
KBFHEIFM_03523 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KBFHEIFM_03524 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KBFHEIFM_03525 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
KBFHEIFM_03526 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
KBFHEIFM_03527 4.04e-194 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
KBFHEIFM_03528 3.44e-48 yvzC - - K - - - transcriptional
KBFHEIFM_03529 4.08e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
KBFHEIFM_03530 9.82e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
KBFHEIFM_03531 3.85e-72 yvaP - - K - - - transcriptional
KBFHEIFM_03532 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KBFHEIFM_03533 9.2e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
KBFHEIFM_03534 8.27e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KBFHEIFM_03535 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
KBFHEIFM_03536 2.99e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KBFHEIFM_03537 1.15e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
KBFHEIFM_03538 9.67e-137 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
KBFHEIFM_03539 2.58e-223 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KBFHEIFM_03540 5.63e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
KBFHEIFM_03541 5.58e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KBFHEIFM_03542 1.74e-130 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
KBFHEIFM_03543 7.95e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
KBFHEIFM_03544 1.03e-145 yvbH - - S - - - YvbH-like oligomerisation region
KBFHEIFM_03545 3.95e-157 yvbI - - M - - - Membrane
KBFHEIFM_03546 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
KBFHEIFM_03547 2.8e-105 yvbK - - K - - - acetyltransferase
KBFHEIFM_03548 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KBFHEIFM_03549 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
KBFHEIFM_03550 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KBFHEIFM_03551 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
KBFHEIFM_03552 4.7e-237 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KBFHEIFM_03553 2.42e-237 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KBFHEIFM_03554 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KBFHEIFM_03555 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
KBFHEIFM_03556 1.04e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KBFHEIFM_03558 3.55e-201 yvbU - - K - - - Transcriptional regulator
KBFHEIFM_03559 3.93e-198 yvbV - - EG - - - EamA-like transporter family
KBFHEIFM_03560 7.07e-307 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
KBFHEIFM_03561 1.48e-249 - - - S - - - Glycosyl hydrolase
KBFHEIFM_03562 1.45e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KBFHEIFM_03563 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
KBFHEIFM_03564 9.08e-175 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KBFHEIFM_03565 4.36e-136 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KBFHEIFM_03566 1.54e-251 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KBFHEIFM_03567 6.83e-169 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
KBFHEIFM_03568 7.76e-205 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
KBFHEIFM_03570 1.46e-200 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
KBFHEIFM_03571 1.52e-265 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
KBFHEIFM_03572 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
KBFHEIFM_03573 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
KBFHEIFM_03574 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
KBFHEIFM_03575 8.76e-300 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
KBFHEIFM_03576 2.67e-291 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
KBFHEIFM_03577 1.3e-236 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
KBFHEIFM_03578 6.85e-146 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
KBFHEIFM_03579 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
KBFHEIFM_03580 9.59e-304 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
KBFHEIFM_03581 5.69e-44 yvfG - - S - - - YvfG protein
KBFHEIFM_03582 2.42e-237 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
KBFHEIFM_03583 1.01e-276 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
KBFHEIFM_03584 1.01e-77 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
KBFHEIFM_03585 3.19e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KBFHEIFM_03586 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KBFHEIFM_03587 1.05e-249 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
KBFHEIFM_03588 9.86e-262 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
KBFHEIFM_03589 1.22e-248 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
KBFHEIFM_03590 3.59e-264 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
KBFHEIFM_03591 2.06e-277 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
KBFHEIFM_03592 1.25e-201 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
KBFHEIFM_03593 2.83e-284 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
KBFHEIFM_03594 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
KBFHEIFM_03595 7.94e-150 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
KBFHEIFM_03596 2.78e-158 epsA - - M ko:K19420 - ko00000 biosynthesis protein
KBFHEIFM_03597 3.57e-98 - - - K ko:K19417 - ko00000,ko03000 transcriptional
KBFHEIFM_03598 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
KBFHEIFM_03600 3.13e-119 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
KBFHEIFM_03601 2.52e-45 - - - S - - - Protein of unknown function (DUF3237)
KBFHEIFM_03602 1.62e-158 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
KBFHEIFM_03603 0.0 pbpE - - V - - - Beta-lactamase
KBFHEIFM_03604 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
KBFHEIFM_03605 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
KBFHEIFM_03606 0.0 ybeC - - E - - - amino acid
KBFHEIFM_03607 1.17e-137 yvdT_1 - - K - - - Transcriptional regulator
KBFHEIFM_03608 1.81e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
KBFHEIFM_03609 8.49e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
KBFHEIFM_03610 9.18e-121 yvdQ - - S - - - Protein of unknown function (DUF3231)
KBFHEIFM_03611 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
KBFHEIFM_03612 1.99e-235 - - - S - - - Patatin-like phospholipase
KBFHEIFM_03614 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KBFHEIFM_03615 3e-153 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
KBFHEIFM_03616 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
KBFHEIFM_03617 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
KBFHEIFM_03618 1.34e-200 malA - - S - - - Protein of unknown function (DUF1189)
KBFHEIFM_03619 6.56e-188 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
KBFHEIFM_03620 8.65e-311 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
KBFHEIFM_03621 1.4e-300 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
KBFHEIFM_03622 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
KBFHEIFM_03623 2.28e-223 yvdE - - K - - - Transcriptional regulator
KBFHEIFM_03624 2.66e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
KBFHEIFM_03625 4.54e-70 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
KBFHEIFM_03626 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
KBFHEIFM_03627 3.73e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
KBFHEIFM_03628 1.34e-233 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KBFHEIFM_03629 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
KBFHEIFM_03630 4.46e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KBFHEIFM_03631 5.61e-251 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
KBFHEIFM_03632 3.84e-171 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KBFHEIFM_03633 1.37e-45 - - - - - - - -
KBFHEIFM_03634 1.89e-181 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
KBFHEIFM_03635 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
KBFHEIFM_03636 3.63e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
KBFHEIFM_03637 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
KBFHEIFM_03638 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
KBFHEIFM_03639 2.39e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KBFHEIFM_03640 1.18e-225 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KBFHEIFM_03641 1.08e-184 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
KBFHEIFM_03642 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
KBFHEIFM_03643 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
KBFHEIFM_03645 0.0 - - - - - - - -
KBFHEIFM_03646 3.26e-95 - - - - - - - -
KBFHEIFM_03647 3.87e-87 - - - - - - - -
KBFHEIFM_03649 6.85e-91 - - - - - - - -
KBFHEIFM_03650 1.01e-116 - - - S - - - Predicted membrane protein (DUF2339)
KBFHEIFM_03651 2.22e-142 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
KBFHEIFM_03652 2.79e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KBFHEIFM_03653 1.32e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KBFHEIFM_03654 1.98e-147 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KBFHEIFM_03655 2.87e-138 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
KBFHEIFM_03656 4.27e-291 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KBFHEIFM_03657 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KBFHEIFM_03658 4.87e-281 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KBFHEIFM_03659 6.12e-179 yvpB - - NU - - - protein conserved in bacteria
KBFHEIFM_03660 7.74e-154 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
KBFHEIFM_03661 1.52e-120 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
KBFHEIFM_03662 3.05e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
KBFHEIFM_03663 3.56e-209 yvoD - - P - - - COG0370 Fe2 transport system protein B
KBFHEIFM_03664 2.61e-194 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KBFHEIFM_03665 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KBFHEIFM_03666 3.42e-279 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
KBFHEIFM_03667 3.27e-170 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KBFHEIFM_03668 8.67e-171 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
KBFHEIFM_03669 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
KBFHEIFM_03670 2.22e-108 yvnA - - K - - - helix_turn_helix multiple antibiotic resistance protein
KBFHEIFM_03671 5.39e-292 cypX 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
KBFHEIFM_03672 3.4e-175 yvmC 2.3.2.22 - S ko:K17485 - ko00000,ko01000 Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
KBFHEIFM_03673 1.03e-112 yvmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
KBFHEIFM_03674 4.26e-272 yvmA - - EGP - - - Major Facilitator Superfamily
KBFHEIFM_03675 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
KBFHEIFM_03676 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
KBFHEIFM_03677 1.66e-220 yvlB - - S - - - Putative adhesin
KBFHEIFM_03678 8.09e-65 yvlA - - - - - - -
KBFHEIFM_03679 2.73e-46 yvkN - - - - - - -
KBFHEIFM_03680 9.95e-64 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KBFHEIFM_03681 9.04e-16 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KBFHEIFM_03682 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KBFHEIFM_03683 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KBFHEIFM_03684 2.54e-42 csbA - - S - - - protein conserved in bacteria
KBFHEIFM_03685 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
KBFHEIFM_03686 4.77e-130 yvkB - - K - - - Transcriptional regulator
KBFHEIFM_03687 2.13e-295 yvkA - - P - - - -transporter
KBFHEIFM_03688 1.29e-279 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KBFHEIFM_03689 1.38e-73 swrA - - S - - - Swarming motility protein
KBFHEIFM_03690 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
KBFHEIFM_03691 1.1e-198 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KBFHEIFM_03692 1.5e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
KBFHEIFM_03693 3.23e-75 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
KBFHEIFM_03694 6.5e-185 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KBFHEIFM_03695 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KBFHEIFM_03696 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KBFHEIFM_03697 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KBFHEIFM_03698 9.14e-88 - - - - - - - -
KBFHEIFM_03699 1.73e-08 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
KBFHEIFM_03700 5.15e-91 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
KBFHEIFM_03701 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KBFHEIFM_03702 3.03e-74 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
KBFHEIFM_03703 2.33e-160 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KBFHEIFM_03704 3.02e-40 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KBFHEIFM_03705 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KBFHEIFM_03706 6.92e-92 yviE - - - - - - -
KBFHEIFM_03707 3.8e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
KBFHEIFM_03708 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
KBFHEIFM_03709 6.78e-100 yvyG - - NOU - - - FlgN protein
KBFHEIFM_03710 1.02e-51 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
KBFHEIFM_03711 1.83e-96 yvyF - - S - - - flagellar protein
KBFHEIFM_03712 7.56e-161 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
KBFHEIFM_03713 1.04e-60 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
KBFHEIFM_03714 3.43e-96 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KBFHEIFM_03715 4.76e-224 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KBFHEIFM_03716 1.77e-198 degV - - S - - - protein conserved in bacteria
KBFHEIFM_03717 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KBFHEIFM_03718 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
KBFHEIFM_03719 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
KBFHEIFM_03720 3.81e-223 yvhJ - - K - - - Transcriptional regulator
KBFHEIFM_03721 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
KBFHEIFM_03722 3.3e-303 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
KBFHEIFM_03723 8.42e-187 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
KBFHEIFM_03724 2.02e-147 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
KBFHEIFM_03725 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
KBFHEIFM_03726 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KBFHEIFM_03727 5.68e-279 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
KBFHEIFM_03728 1.03e-315 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KBFHEIFM_03729 1.49e-143 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KBFHEIFM_03730 9e-109 - - - M - - - Glycosyltransferase like family 2
KBFHEIFM_03731 2.61e-264 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
KBFHEIFM_03732 0.0 lytB - - D - - - Stage II sporulation protein
KBFHEIFM_03733 5.88e-17 - - - - - - - -
KBFHEIFM_03734 1.16e-211 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
KBFHEIFM_03735 1.17e-271 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KBFHEIFM_03736 2.09e-103 - - - M - - - Glycosyltransferase like family 2
KBFHEIFM_03737 8.61e-119 - - - M - - - Glycosyl transferases group 1
KBFHEIFM_03739 3.9e-208 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
KBFHEIFM_03740 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KBFHEIFM_03741 1.67e-168 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
KBFHEIFM_03742 0.0 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KBFHEIFM_03743 2.19e-305 - - - M - - - Glycosyltransferase like family 2
KBFHEIFM_03744 1.2e-170 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KBFHEIFM_03745 1.32e-73 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
KBFHEIFM_03746 1.95e-110 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KBFHEIFM_03747 1.09e-116 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KBFHEIFM_03748 2.07e-134 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
KBFHEIFM_03749 5.68e-186 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
KBFHEIFM_03750 1.34e-109 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - M ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KBFHEIFM_03751 2.86e-235 tarL 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KBFHEIFM_03752 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KBFHEIFM_03753 2.73e-240 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
KBFHEIFM_03754 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
KBFHEIFM_03755 1.38e-253 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
KBFHEIFM_03756 1e-269 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
KBFHEIFM_03757 3.71e-314 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KBFHEIFM_03758 1.48e-222 ywtF_2 - - K - - - Transcriptional regulator
KBFHEIFM_03759 1.46e-204 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
KBFHEIFM_03760 4.58e-303 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KBFHEIFM_03761 1.33e-28 ywtC - - - - - - -
KBFHEIFM_03762 1.33e-277 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
KBFHEIFM_03763 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
KBFHEIFM_03764 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
KBFHEIFM_03765 1.09e-226 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
KBFHEIFM_03766 2.62e-206 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KBFHEIFM_03767 3.24e-84 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KBFHEIFM_03768 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
KBFHEIFM_03769 3.35e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KBFHEIFM_03770 6.36e-204 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
KBFHEIFM_03771 9.76e-120 batE - - T - - - Sh3 type 3 domain protein
KBFHEIFM_03772 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
KBFHEIFM_03773 8.76e-126 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
KBFHEIFM_03774 1.84e-187 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
KBFHEIFM_03775 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
KBFHEIFM_03776 3.36e-218 alsR - - K - - - LysR substrate binding domain
KBFHEIFM_03777 1.38e-280 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KBFHEIFM_03778 9.09e-164 ywrJ - - - - - - -
KBFHEIFM_03779 3.51e-190 cotB - - - ko:K06325 - ko00000 -
KBFHEIFM_03780 9.22e-269 cotH - - M ko:K06330 - ko00000 Spore Coat
KBFHEIFM_03781 2.17e-16 - - - - - - - -
KBFHEIFM_03782 7.22e-142 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KBFHEIFM_03783 1.13e-70 - - - S - - - Domain of unknown function (DUF4181)
KBFHEIFM_03784 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
KBFHEIFM_03785 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
KBFHEIFM_03786 4.53e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
KBFHEIFM_03787 6.07e-114 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
KBFHEIFM_03789 1.5e-129 ywqN - - S - - - NAD(P)H-dependent
KBFHEIFM_03790 4.73e-209 - - - K - - - Transcriptional regulator
KBFHEIFM_03791 3.56e-149 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
KBFHEIFM_03793 2.04e-302 ywqJ - - S - - - Pre-toxin TG
KBFHEIFM_03794 8.84e-52 ywqI - - S - - - Family of unknown function (DUF5344)
KBFHEIFM_03796 1.64e-193 ywqG - - S - - - Domain of unknown function (DUF1963)
KBFHEIFM_03797 4.66e-313 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KBFHEIFM_03798 1.75e-180 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
KBFHEIFM_03799 5.89e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
KBFHEIFM_03800 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
KBFHEIFM_03801 3.6e-25 - - - - - - - -
KBFHEIFM_03802 0.0 ywqB - - S - - - SWIM zinc finger
KBFHEIFM_03803 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
KBFHEIFM_03804 3.72e-202 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
KBFHEIFM_03805 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
KBFHEIFM_03806 8.53e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
KBFHEIFM_03807 5.26e-88 ywpG - - - - - - -
KBFHEIFM_03808 8.81e-89 ywpF - - S - - - YwpF-like protein
KBFHEIFM_03809 6.34e-66 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
KBFHEIFM_03810 8.54e-198 ywpD - - T - - - Histidine kinase
KBFHEIFM_03811 1.13e-79 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KBFHEIFM_03812 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KBFHEIFM_03813 4.47e-256 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
KBFHEIFM_03814 4.1e-182 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
KBFHEIFM_03815 8.4e-171 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
KBFHEIFM_03816 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
KBFHEIFM_03817 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
KBFHEIFM_03818 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
KBFHEIFM_03819 3.92e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
KBFHEIFM_03820 2.92e-312 ywoF - - P - - - Right handed beta helix region
KBFHEIFM_03821 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
KBFHEIFM_03822 7.65e-307 ywoD - - EGP - - - Major facilitator superfamily
KBFHEIFM_03823 1.48e-133 yjgF - - Q - - - Isochorismatase family
KBFHEIFM_03824 1.06e-100 - - - - - - - -
KBFHEIFM_03825 6.5e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
KBFHEIFM_03826 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
KBFHEIFM_03827 4.07e-133 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
KBFHEIFM_03828 8.15e-92 ywnJ - - S - - - VanZ like family
KBFHEIFM_03829 1.85e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
KBFHEIFM_03830 4.99e-113 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
KBFHEIFM_03831 2.22e-16 ywnC - - S - - - Family of unknown function (DUF5362)
KBFHEIFM_03832 7.07e-92 ywnF - - S - - - Family of unknown function (DUF5392)
KBFHEIFM_03833 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KBFHEIFM_03834 2.69e-93 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
KBFHEIFM_03835 1.24e-77 ywnC - - S - - - Family of unknown function (DUF5362)
KBFHEIFM_03836 4.32e-147 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
KBFHEIFM_03837 4.58e-85 ywnA - - K - - - Transcriptional regulator
KBFHEIFM_03838 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KBFHEIFM_03839 3.2e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
KBFHEIFM_03840 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
KBFHEIFM_03841 1.11e-21 csbD - - K - - - CsbD-like
KBFHEIFM_03842 2.18e-109 ywmF - - S - - - Peptidase M50
KBFHEIFM_03843 3.1e-129 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
KBFHEIFM_03844 1.08e-245 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KBFHEIFM_03845 5.24e-186 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KBFHEIFM_03847 1.02e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
KBFHEIFM_03848 1.89e-157 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
KBFHEIFM_03849 4.64e-232 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
KBFHEIFM_03850 1e-305 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KBFHEIFM_03851 2.68e-171 ywmB - - S - - - TATA-box binding
KBFHEIFM_03852 4.54e-45 ywzB - - S - - - membrane
KBFHEIFM_03853 7.16e-114 ywmA - - - - - - -
KBFHEIFM_03854 3.89e-72 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
KBFHEIFM_03855 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KBFHEIFM_03856 1.28e-194 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KBFHEIFM_03857 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KBFHEIFM_03858 2.89e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KBFHEIFM_03859 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KBFHEIFM_03860 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KBFHEIFM_03861 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
KBFHEIFM_03862 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
KBFHEIFM_03863 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KBFHEIFM_03864 4.36e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KBFHEIFM_03865 2.49e-123 ywlG - - S - - - Belongs to the UPF0340 family
KBFHEIFM_03866 1.36e-105 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
KBFHEIFM_03867 1.58e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KBFHEIFM_03868 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
KBFHEIFM_03869 1.22e-249 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KBFHEIFM_03870 1.79e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
KBFHEIFM_03871 1.14e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
KBFHEIFM_03872 9.69e-74 ywlA - - S - - - Uncharacterised protein family (UPF0715)
KBFHEIFM_03874 2.42e-204 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KBFHEIFM_03875 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KBFHEIFM_03876 1.19e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KBFHEIFM_03877 1.72e-116 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
KBFHEIFM_03878 4.6e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
KBFHEIFM_03879 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
KBFHEIFM_03880 9.96e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
KBFHEIFM_03881 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
KBFHEIFM_03882 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KBFHEIFM_03883 3.51e-225 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
KBFHEIFM_03884 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KBFHEIFM_03885 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KBFHEIFM_03886 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
KBFHEIFM_03887 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
KBFHEIFM_03888 9.11e-118 ywjG - - S - - - Domain of unknown function (DUF2529)
KBFHEIFM_03889 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KBFHEIFM_03890 2.07e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KBFHEIFM_03891 1.73e-268 acdA - - I - - - acyl-CoA dehydrogenase
KBFHEIFM_03892 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
KBFHEIFM_03893 6.74e-287 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
KBFHEIFM_03894 8.09e-235 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
KBFHEIFM_03895 1.32e-57 ywjC - - - - - - -
KBFHEIFM_03896 5.28e-122 ywjB - - H - - - RibD C-terminal domain
KBFHEIFM_03897 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
KBFHEIFM_03898 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KBFHEIFM_03899 5.91e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
KBFHEIFM_03900 1.18e-123 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
KBFHEIFM_03901 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
KBFHEIFM_03902 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KBFHEIFM_03903 8.67e-111 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
KBFHEIFM_03904 1.84e-179 ywiC - - S - - - YwiC-like protein
KBFHEIFM_03905 2.3e-168 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
KBFHEIFM_03906 1.2e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
KBFHEIFM_03907 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
KBFHEIFM_03908 4.64e-96 ywiB - - S - - - protein conserved in bacteria
KBFHEIFM_03909 3.71e-12 - - - S - - - Bacteriocin subtilosin A
KBFHEIFM_03910 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
KBFHEIFM_03912 1.5e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KBFHEIFM_03913 1.7e-297 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
KBFHEIFM_03914 5.69e-275 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
KBFHEIFM_03915 4.68e-315 - - - L - - - Peptidase, M16
KBFHEIFM_03917 0.0 ywhL - - CO - - - amine dehydrogenase activity
KBFHEIFM_03918 6.88e-284 ywhK - - CO - - - amine dehydrogenase activity
KBFHEIFM_03919 3.28e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
KBFHEIFM_03922 1.3e-10 - - - - - - - -
KBFHEIFM_03925 1.4e-74 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KBFHEIFM_03927 6.02e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
KBFHEIFM_03928 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KBFHEIFM_03929 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KBFHEIFM_03930 7.52e-121 ywhD - - S - - - YwhD family
KBFHEIFM_03931 1.9e-153 ywhC - - S - - - Peptidase family M50
KBFHEIFM_03932 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
KBFHEIFM_03933 1.45e-93 ywhA - - K - - - Transcriptional regulator
KBFHEIFM_03934 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KBFHEIFM_03936 2e-302 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
KBFHEIFM_03937 7.42e-102 yffB - - K - - - Transcriptional regulator
KBFHEIFM_03938 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
KBFHEIFM_03939 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
KBFHEIFM_03940 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
KBFHEIFM_03941 5.65e-147 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
KBFHEIFM_03942 2.5e-201 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
KBFHEIFM_03943 2.15e-199 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
KBFHEIFM_03944 3.73e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
KBFHEIFM_03945 1.67e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
KBFHEIFM_03946 3.43e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
KBFHEIFM_03947 7.94e-175 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
KBFHEIFM_03948 2.58e-296 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
KBFHEIFM_03949 3.91e-268 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
KBFHEIFM_03950 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
KBFHEIFM_03951 3.14e-178 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KBFHEIFM_03952 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
KBFHEIFM_03953 8.48e-145 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
KBFHEIFM_03954 6.3e-274 ywfA - - EGP - - - -transporter
KBFHEIFM_03955 2.65e-316 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
KBFHEIFM_03956 0.0 rocB - - E - - - arginine degradation protein
KBFHEIFM_03957 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
KBFHEIFM_03958 2.11e-310 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
KBFHEIFM_03959 1.51e-100 - - - - - - - -
KBFHEIFM_03960 1.52e-112 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
KBFHEIFM_03961 4.72e-204 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KBFHEIFM_03962 1.51e-232 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KBFHEIFM_03963 7.45e-178 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KBFHEIFM_03964 2.84e-240 spsG - - M - - - Spore Coat
KBFHEIFM_03965 3.51e-164 spsF - - M ko:K07257 - ko00000 Spore Coat
KBFHEIFM_03966 4.59e-270 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
KBFHEIFM_03967 4.22e-210 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
KBFHEIFM_03968 6.44e-285 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
KBFHEIFM_03969 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
KBFHEIFM_03970 4.68e-186 spsA - - M - - - Spore Coat
KBFHEIFM_03971 3.62e-112 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
KBFHEIFM_03972 1.59e-78 ywdK - - S - - - small membrane protein
KBFHEIFM_03973 5.1e-301 ywdJ - - F - - - Xanthine uracil
KBFHEIFM_03974 4.4e-63 ywdI - - S - - - Family of unknown function (DUF5327)
KBFHEIFM_03975 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KBFHEIFM_03976 2.71e-165 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KBFHEIFM_03977 2.71e-191 ywdF - - S - - - Glycosyltransferase like family 2
KBFHEIFM_03979 3.56e-145 ywdD - - - - - - -
KBFHEIFM_03980 1.6e-75 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
KBFHEIFM_03981 2.21e-187 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
KBFHEIFM_03982 1.25e-38 ywdA - - - - - - -
KBFHEIFM_03983 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
KBFHEIFM_03984 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KBFHEIFM_03985 8e-178 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
KBFHEIFM_03986 7.44e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
KBFHEIFM_03988 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KBFHEIFM_03989 9.87e-238 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KBFHEIFM_03990 9.4e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
KBFHEIFM_03991 1.26e-268 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
KBFHEIFM_03992 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
KBFHEIFM_03993 7.55e-82 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
KBFHEIFM_03994 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
KBFHEIFM_03995 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KBFHEIFM_03996 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
KBFHEIFM_03997 5.11e-49 ydaS - - S - - - membrane
KBFHEIFM_03998 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
KBFHEIFM_03999 4.2e-286 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KBFHEIFM_04000 2.25e-75 gtcA - - S - - - GtrA-like protein
KBFHEIFM_04001 3.42e-158 ywcC - - K - - - transcriptional regulator
KBFHEIFM_04003 3.02e-64 ywcB - - S - - - Protein of unknown function, DUF485
KBFHEIFM_04004 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KBFHEIFM_04005 5.38e-143 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
KBFHEIFM_04006 1.04e-306 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
KBFHEIFM_04007 2.42e-246 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
KBFHEIFM_04008 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
KBFHEIFM_04009 1.74e-146 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KBFHEIFM_04010 1.32e-184 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KBFHEIFM_04011 2.7e-203 ywbI - - K - - - Transcriptional regulator
KBFHEIFM_04012 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
KBFHEIFM_04013 1.21e-143 ywbG - - M - - - effector of murein hydrolase
KBFHEIFM_04014 1.76e-276 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
KBFHEIFM_04015 3.13e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
KBFHEIFM_04016 4e-280 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
KBFHEIFM_04017 4.01e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
KBFHEIFM_04018 8.61e-310 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KBFHEIFM_04019 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KBFHEIFM_04020 6.87e-311 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KBFHEIFM_04021 2.6e-195 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
KBFHEIFM_04022 4.41e-215 gspA - - M - - - General stress
KBFHEIFM_04023 5.18e-160 ywaF - - S - - - Integral membrane protein
KBFHEIFM_04024 3.57e-114 ywaE - - K - - - Transcriptional regulator
KBFHEIFM_04025 1.56e-297 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KBFHEIFM_04026 1.83e-316 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
KBFHEIFM_04027 2.67e-116 - - - K - - - Helix-turn-helix XRE-family like proteins
KBFHEIFM_04028 5.58e-64 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
KBFHEIFM_04029 4.57e-164 - - - EGP - - - Permeases of the major facilitator superfamily
KBFHEIFM_04030 1.46e-148 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
KBFHEIFM_04031 5.7e-210 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
KBFHEIFM_04032 1.27e-20 - - - S - - - D-Ala-teichoic acid biosynthesis protein
KBFHEIFM_04033 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KBFHEIFM_04034 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
KBFHEIFM_04035 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KBFHEIFM_04036 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KBFHEIFM_04037 4.83e-177 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
KBFHEIFM_04038 4.36e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
KBFHEIFM_04039 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KBFHEIFM_04040 8.33e-68 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KBFHEIFM_04041 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KBFHEIFM_04042 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
KBFHEIFM_04043 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
KBFHEIFM_04044 8.94e-28 yxzF - - - - - - -
KBFHEIFM_04045 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
KBFHEIFM_04046 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
KBFHEIFM_04047 3.52e-274 yxlH - - EGP - - - Major Facilitator Superfamily
KBFHEIFM_04048 1.88e-177 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KBFHEIFM_04049 1.41e-211 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KBFHEIFM_04050 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
KBFHEIFM_04051 2.92e-42 - - - - - - - -
KBFHEIFM_04052 4.05e-64 yxlC - - S - - - Family of unknown function (DUF5345)
KBFHEIFM_04053 1.29e-124 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KBFHEIFM_04054 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
KBFHEIFM_04055 1.52e-201 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KBFHEIFM_04056 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
KBFHEIFM_04057 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
KBFHEIFM_04058 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
KBFHEIFM_04059 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
KBFHEIFM_04060 3.97e-310 cimH - - C - - - COG3493 Na citrate symporter
KBFHEIFM_04061 0.0 - - - O - - - Peptidase family M48
KBFHEIFM_04063 8.75e-198 yxkH - - G - - - Polysaccharide deacetylase
KBFHEIFM_04064 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KBFHEIFM_04065 2.25e-209 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
KBFHEIFM_04066 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KBFHEIFM_04067 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
KBFHEIFM_04068 1.95e-99 yxkC - - S - - - Domain of unknown function (DUF4352)
KBFHEIFM_04069 6.06e-251 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
KBFHEIFM_04070 9.35e-101 - - - S - - - Protein of unknown function (DUF1453)
KBFHEIFM_04071 3.23e-257 - - - T - - - Signal transduction histidine kinase
KBFHEIFM_04072 1.1e-147 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
KBFHEIFM_04073 7.76e-299 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
KBFHEIFM_04076 2.88e-111 yxjI - - S - - - LURP-one-related
KBFHEIFM_04077 3.02e-277 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
KBFHEIFM_04078 3.81e-276 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
KBFHEIFM_04079 2.77e-174 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
KBFHEIFM_04080 5.91e-151 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KBFHEIFM_04081 1.33e-167 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KBFHEIFM_04082 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
KBFHEIFM_04083 4.55e-206 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
KBFHEIFM_04084 2.98e-269 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KBFHEIFM_04085 8.47e-133 - - - T - - - Domain of unknown function (DUF4163)
KBFHEIFM_04086 1.09e-61 yxiS - - - - - - -
KBFHEIFM_04087 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
KBFHEIFM_04088 1.16e-283 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
KBFHEIFM_04089 1.77e-183 bglS - - M - - - licheninase activity
KBFHEIFM_04090 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
KBFHEIFM_04091 1.07e-142 - - - - - - - -
KBFHEIFM_04092 7.02e-288 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
KBFHEIFM_04093 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
KBFHEIFM_04094 8.65e-275 - - - E - - - GDSL-like Lipase/Acylhydrolase
KBFHEIFM_04097 5.53e-65 yxiJ - - S - - - YxiJ-like protein
KBFHEIFM_04098 3.79e-125 yxiI - - S - - - Protein of unknown function (DUF2716)
KBFHEIFM_04099 6.22e-107 - - - - - - - -
KBFHEIFM_04100 1.2e-57 - - - - - - - -
KBFHEIFM_04101 8.76e-99 yxiG - - - - - - -
KBFHEIFM_04102 1.12e-82 - - - - - - - -
KBFHEIFM_04103 3.69e-111 - - - - - - - -
KBFHEIFM_04104 1.09e-94 yxxG - - - - - - -
KBFHEIFM_04105 0.0 wapA - - M - - - COG3209 Rhs family protein
KBFHEIFM_04106 2.16e-212 yxxF - - EG - - - EamA-like transporter family
KBFHEIFM_04107 2e-93 yxiE - - T - - - Belongs to the universal stress protein A family
KBFHEIFM_04108 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KBFHEIFM_04109 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KBFHEIFM_04110 2.54e-13 - - - - - - - -
KBFHEIFM_04111 3.73e-52 - - - - - - - -
KBFHEIFM_04112 9.02e-76 - - - - - - - -
KBFHEIFM_04113 5.46e-38 - - - - - - - -
KBFHEIFM_04114 1.9e-55 - - - - - - - -
KBFHEIFM_04116 2.48e-59 - - - - - - - -
KBFHEIFM_04117 3.94e-274 - - - S - - - nuclease activity
KBFHEIFM_04118 1.33e-52 yxiC - - S - - - Family of unknown function (DUF5344)
KBFHEIFM_04119 5.89e-34 - - - S - - - Domain of unknown function (DUF5082)
KBFHEIFM_04120 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
KBFHEIFM_04121 7.02e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
KBFHEIFM_04122 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
KBFHEIFM_04123 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KBFHEIFM_04124 7.8e-300 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
KBFHEIFM_04125 8.04e-230 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
KBFHEIFM_04126 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
KBFHEIFM_04127 8.11e-299 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
KBFHEIFM_04128 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KBFHEIFM_04129 1.96e-148 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KBFHEIFM_04130 4.97e-221 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KBFHEIFM_04131 3.56e-195 - - - S - - - Domain of Unknown Function (DUF1206)
KBFHEIFM_04132 2.21e-255 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
KBFHEIFM_04133 5.04e-315 yxeQ - - S - - - MmgE/PrpD family
KBFHEIFM_04134 4.1e-272 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
KBFHEIFM_04135 1.67e-171 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KBFHEIFM_04136 3e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
KBFHEIFM_04137 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
KBFHEIFM_04138 2.99e-119 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KBFHEIFM_04139 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KBFHEIFM_04140 6.97e-240 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
KBFHEIFM_04141 5.69e-194 yxeH - - S - - - hydrolases of the HAD superfamily
KBFHEIFM_04144 5.99e-41 yxeE - - - - - - -
KBFHEIFM_04145 4.34e-27 yxeD - - - - - - -
KBFHEIFM_04146 1.13e-89 - - - - - - - -
KBFHEIFM_04147 7.4e-227 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KBFHEIFM_04148 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
KBFHEIFM_04149 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
KBFHEIFM_04150 1.49e-178 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KBFHEIFM_04151 6.09e-228 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KBFHEIFM_04152 2.8e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KBFHEIFM_04153 6.95e-205 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
KBFHEIFM_04154 1.09e-186 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
KBFHEIFM_04155 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
KBFHEIFM_04156 4.44e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
KBFHEIFM_04157 2.32e-295 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
KBFHEIFM_04158 7.09e-222 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
KBFHEIFM_04159 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
KBFHEIFM_04160 1.23e-227 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
KBFHEIFM_04161 1.64e-198 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
KBFHEIFM_04162 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KBFHEIFM_04163 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
KBFHEIFM_04164 3.52e-224 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
KBFHEIFM_04166 2.13e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
KBFHEIFM_04167 1.02e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KBFHEIFM_04168 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
KBFHEIFM_04170 1.19e-192 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
KBFHEIFM_04171 2.84e-263 yxbF - - K - - - Bacterial regulatory proteins, tetR family
KBFHEIFM_04172 3.98e-312 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KBFHEIFM_04174 1.18e-26 yxaI - - S - - - membrane protein domain
KBFHEIFM_04175 2.63e-137 yxaL - - S - - - PQQ-like domain
KBFHEIFM_04176 3.11e-80 - - - S - - - Family of unknown function (DUF5391)
KBFHEIFM_04177 4.03e-99 yxaI - - S - - - membrane protein domain
KBFHEIFM_04178 3.08e-285 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
KBFHEIFM_04179 1.05e-250 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
KBFHEIFM_04180 3.22e-129 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
KBFHEIFM_04181 8.67e-255 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KBFHEIFM_04182 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
KBFHEIFM_04183 1.03e-77 - - - S ko:K06518 - ko00000,ko02000 LrgA family
KBFHEIFM_04184 2.19e-153 yxaC - - M - - - effector of murein hydrolase
KBFHEIFM_04185 7.3e-245 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
KBFHEIFM_04186 4.71e-263 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
KBFHEIFM_04187 4.42e-164 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
KBFHEIFM_04188 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
KBFHEIFM_04189 2.05e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
KBFHEIFM_04190 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KBFHEIFM_04191 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
KBFHEIFM_04192 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
KBFHEIFM_04193 2.24e-237 - - - S - - - Polysaccharide pyruvyl transferase
KBFHEIFM_04194 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KBFHEIFM_04195 7.55e-44 - 2.7.1.199 - G ko:K02777,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system
KBFHEIFM_04196 1.13e-158 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
KBFHEIFM_04197 8.35e-24 - - - - - - - -
KBFHEIFM_04198 5.49e-152 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
KBFHEIFM_04199 2.06e-143 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KBFHEIFM_04200 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
KBFHEIFM_04201 3.66e-304 - - - O - - - Subtilase family
KBFHEIFM_04202 1.77e-127 - - - O - - - ATPase family associated with various cellular activities (AAA)
KBFHEIFM_04203 8.3e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KBFHEIFM_04205 5.28e-86 - - - - - - - -
KBFHEIFM_04206 5.2e-297 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KBFHEIFM_04208 1.58e-41 yycQ - - S - - - Protein of unknown function (DUF2651)
KBFHEIFM_04209 2.83e-262 yycP - - - - - - -
KBFHEIFM_04210 4.81e-169 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KBFHEIFM_04211 2.92e-108 yycN - - K - - - Acetyltransferase
KBFHEIFM_04212 1.01e-237 - - - S - - - aspartate phosphatase
KBFHEIFM_04214 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
KBFHEIFM_04215 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
KBFHEIFM_04216 2.04e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
KBFHEIFM_04217 5.82e-20 - - - - - - - -
KBFHEIFM_04218 1.2e-119 - - - - - - - -
KBFHEIFM_04219 6.81e-19 - - - S - - - Sporulation delaying protein SdpA
KBFHEIFM_04220 3.95e-87 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
KBFHEIFM_04221 2.7e-53 sdpR - - K - - - transcriptional
KBFHEIFM_04222 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
KBFHEIFM_04223 9.16e-215 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
KBFHEIFM_04224 6.75e-122 - - - K ko:K02483 - ko00000,ko02022 PFAM response regulator receiver
KBFHEIFM_04225 2.16e-96 - - - S - - - Peptidase propeptide and YPEB domain
KBFHEIFM_04226 2.2e-42 - - - S - - - Peptidase propeptide and YPEB domain
KBFHEIFM_04227 1.56e-277 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KBFHEIFM_04228 1.15e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
KBFHEIFM_04229 9.86e-200 yycI - - S - - - protein conserved in bacteria
KBFHEIFM_04230 0.0 yycH - - S - - - protein conserved in bacteria
KBFHEIFM_04231 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KBFHEIFM_04232 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KBFHEIFM_04237 1.29e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KBFHEIFM_04238 2.32e-99 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KBFHEIFM_04239 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
KBFHEIFM_04240 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
KBFHEIFM_04242 1.89e-22 yycC - - K - - - YycC-like protein
KBFHEIFM_04243 6.95e-282 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
KBFHEIFM_04244 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KBFHEIFM_04245 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
KBFHEIFM_04246 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
KBFHEIFM_04247 1.5e-204 yybS - - S - - - membrane
KBFHEIFM_04249 2.89e-110 cotF - - M ko:K06329 - ko00000 Spore coat protein
KBFHEIFM_04250 1.3e-87 yybR - - K - - - Transcriptional regulator
KBFHEIFM_04251 4.89e-210 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
KBFHEIFM_04252 1.3e-89 - - - - - - - -
KBFHEIFM_04254 1.01e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KBFHEIFM_04255 4.38e-142 - - - K - - - TipAS antibiotic-recognition domain
KBFHEIFM_04256 2.39e-182 - - - - - - - -
KBFHEIFM_04257 4.29e-88 - - - S - - - SnoaL-like domain
KBFHEIFM_04258 3.28e-161 yybG - - S - - - Pentapeptide repeat-containing protein
KBFHEIFM_04259 4.31e-277 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KBFHEIFM_04260 1.31e-210 yybE - - K - - - Transcriptional regulator
KBFHEIFM_04261 2.18e-101 yjcF - - S - - - Acetyltransferase (GNAT) domain
KBFHEIFM_04262 1.22e-97 yybC - - - - - - -
KBFHEIFM_04263 2.16e-164 - - - S - - - Metallo-beta-lactamase superfamily
KBFHEIFM_04264 4.54e-100 yybA - - K - - - transcriptional
KBFHEIFM_04265 4.05e-93 yjcF - - S - - - Acetyltransferase (GNAT) domain
KBFHEIFM_04266 1.05e-125 yyaS - - S ko:K07149 - ko00000 Membrane
KBFHEIFM_04267 5.49e-119 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
KBFHEIFM_04268 1.75e-84 - - - S - - - YjbR
KBFHEIFM_04269 1.74e-136 yyaP - - H - - - RibD C-terminal domain
KBFHEIFM_04270 0.0 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
KBFHEIFM_04271 5.61e-33 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
KBFHEIFM_04272 3.8e-51 ydeP3 - - K - - - HxlR-like helix-turn-helix
KBFHEIFM_04273 3.16e-172 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
KBFHEIFM_04274 1.15e-99 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Catalyzes the reduction of arsenate As(V) to arsenite As(III)
KBFHEIFM_04275 4.81e-231 arsB - - P ko:K03325 - ko00000,ko02000 Arsenic resistance protein
KBFHEIFM_04276 5.55e-90 cadI 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KBFHEIFM_04277 2.97e-70 arsR - - K ko:K03892 - ko00000,ko03000 ArsR family transcriptional regulator
KBFHEIFM_04278 6.81e-109 - - - E - - - Transglutaminase-like superfamily
KBFHEIFM_04279 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
KBFHEIFM_04280 1.16e-212 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
KBFHEIFM_04281 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
KBFHEIFM_04282 3.81e-129 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
KBFHEIFM_04283 7.2e-90 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KBFHEIFM_04284 2.49e-229 ccpB - - K - - - Transcriptional regulator
KBFHEIFM_04285 1.63e-184 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
KBFHEIFM_04286 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KBFHEIFM_04287 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KBFHEIFM_04288 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
KBFHEIFM_04289 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KBFHEIFM_04290 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KBFHEIFM_04291 7.41e-45 yyzM - - S - - - protein conserved in bacteria
KBFHEIFM_04292 5.34e-227 yyaD - - S - - - Membrane
KBFHEIFM_04293 4.53e-145 yyaC - - S - - - Sporulation protein YyaC
KBFHEIFM_04294 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
KBFHEIFM_04295 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
KBFHEIFM_04296 5.36e-97 - - - S - - - Bacterial PH domain
KBFHEIFM_04297 9e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
KBFHEIFM_04298 1.01e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
KBFHEIFM_04299 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KBFHEIFM_04300 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KBFHEIFM_04301 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
KBFHEIFM_04302 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KBFHEIFM_04303 5.7e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)