Read a JSON File

ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HKEFDBOL_00001	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HKEFDBOL_00002	5.38e-39	-	-	-	-	-	-	-	-
HKEFDBOL_00003	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HKEFDBOL_00004	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HKEFDBOL_00005	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HKEFDBOL_00006	5.58e-191	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKEFDBOL_00007	1.87e-81	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HKEFDBOL_00008	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HKEFDBOL_00009	1.92e-315	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKEFDBOL_00010	1.05e-240	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HKEFDBOL_00011	1.13e-48	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HKEFDBOL_00012	5.14e-268	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HKEFDBOL_00013	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKEFDBOL_00014	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKEFDBOL_00015	1.93e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HKEFDBOL_00016	7.46e-108	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HKEFDBOL_00017	1.89e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HKEFDBOL_00018	4.75e-239	-	-	-	M	-	-	-	Glycosyl transferase
HKEFDBOL_00019	3.67e-225	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
HKEFDBOL_00020	1.11e-154	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HKEFDBOL_00021	2.42e-204	-	-	-	L	-	-	-	HNH nucleases
HKEFDBOL_00022	3.35e-170	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
HKEFDBOL_00023	8.73e-53	-	-	-	S	-	-	-	Transglycosylase associated protein
HKEFDBOL_00024	2.66e-157	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HKEFDBOL_00025	4.09e-11	-	-	-	L	ko:K07496	-	ko00000	Transposase
HKEFDBOL_00026	8.17e-18	-	-	-	S	-	-	-	Transposase C of IS166 homeodomain
HKEFDBOL_00027	7.23e-78	-	-	-	L	ko:K07484	-	ko00000	IS66 Orf2 like protein
HKEFDBOL_00028	5.91e-08	-	-	-	-	-	-	-	-
HKEFDBOL_00029	1.94e-217	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HKEFDBOL_00030	9.08e-234	-	-	-	K	-	-	-	Transcriptional regulator
HKEFDBOL_00031	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKEFDBOL_00032	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKEFDBOL_00033	9.39e-141	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HKEFDBOL_00034	0.0	snf	-	-	KL	-	-	-	domain protein
HKEFDBOL_00035	1.73e-48	-	-	-	-	-	-	-	-
HKEFDBOL_00036	1.24e-08	-	-	-	-	-	-	-	-
HKEFDBOL_00037	4.83e-136	pncA	-	-	Q	-	-	-	Isochorismatase family
HKEFDBOL_00038	1.51e-159	-	-	-	-	-	-	-	-
HKEFDBOL_00041	4.13e-83	-	-	-	-	-	-	-	-
HKEFDBOL_00042	3.56e-47	-	-	-	-	-	-	-	-
HKEFDBOL_00043	9.91e-150	-	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HKEFDBOL_00044	9.67e-104	-	-	-	-	-	-	-	-
HKEFDBOL_00045	6.74e-309	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HKEFDBOL_00046	1.68e-277	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HKEFDBOL_00047	1.85e-90	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HKEFDBOL_00048	1.18e-139	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HKEFDBOL_00049	8.47e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HKEFDBOL_00050	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HKEFDBOL_00051	1.92e-148	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKEFDBOL_00052	6.91e-149	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
HKEFDBOL_00053	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HKEFDBOL_00054	1.66e-116	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
HKEFDBOL_00055	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HKEFDBOL_00056	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HKEFDBOL_00057	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HKEFDBOL_00058	3.02e-173	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
HKEFDBOL_00059	5.87e-228	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HKEFDBOL_00060	2.71e-260	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HKEFDBOL_00061	4.87e-236	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HKEFDBOL_00062	1.28e-150	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HKEFDBOL_00063	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HKEFDBOL_00064	4.4e-215	-	-	-	-	-	-	-	-
HKEFDBOL_00065	4.01e-184	-	-	-	-	-	-	-	-
HKEFDBOL_00066	1.27e-133	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HKEFDBOL_00067	3.49e-36	-	-	-	-	-	-	-	-
HKEFDBOL_00068	3.85e-193	-	-	-	-	-	-	-	-
HKEFDBOL_00069	2.54e-176	-	-	-	-	-	-	-	-
HKEFDBOL_00070	1.65e-180	-	-	-	-	-	-	-	-
HKEFDBOL_00071	1.33e-161	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKEFDBOL_00072	1.25e-80	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
HKEFDBOL_00073	2.86e-307	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HKEFDBOL_00074	8.12e-196	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HKEFDBOL_00075	2.8e-159	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HKEFDBOL_00076	5.37e-106	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HKEFDBOL_00077	4.34e-166	-	-	-	S	-	-	-	Peptidase family M23
HKEFDBOL_00078	9e-255	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HKEFDBOL_00079	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HKEFDBOL_00080	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HKEFDBOL_00081	9.03e-229	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HKEFDBOL_00082	3.38e-172	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HKEFDBOL_00083	1.37e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HKEFDBOL_00084	3.58e-129	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HKEFDBOL_00085	1.74e-224	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HKEFDBOL_00086	1.08e-92	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HKEFDBOL_00087	4.83e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HKEFDBOL_00088	6.94e-199	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HKEFDBOL_00089	1.34e-22	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
HKEFDBOL_00090	2e-149	-	-	-	S	-	-	-	Peptidase family M23
HKEFDBOL_00091	1.22e-136	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKEFDBOL_00093	2.83e-205	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKEFDBOL_00094	5.47e-151	-	-	-	-	-	-	-	-
HKEFDBOL_00095	3.06e-202	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HKEFDBOL_00096	2.95e-283	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HKEFDBOL_00097	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HKEFDBOL_00098	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HKEFDBOL_00099	6.83e-133	yrgI	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Histidine phosphatase superfamily (branch 1)
HKEFDBOL_00100	0.0	-	-	-	L	-	-	-	PLD-like domain
HKEFDBOL_00101	5.97e-55	-	-	-	S	-	-	-	SnoaL-like domain
HKEFDBOL_00102	6.13e-70	-	-	-	K	-	-	-	sequence-specific DNA binding
HKEFDBOL_00103	8.71e-31	-	-	-	G	-	-	-	Ribose/Galactose Isomerase
HKEFDBOL_00104	5.51e-35	-	-	-	-	-	-	-	-
HKEFDBOL_00105	1.15e-64	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HKEFDBOL_00106	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HKEFDBOL_00107	5.88e-157	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKEFDBOL_00108	4.99e-150	-	-	-	-	-	-	-	-
HKEFDBOL_00109	5.04e-154	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
HKEFDBOL_00110	1.13e-126	-	-	-	-	-	-	-	-
HKEFDBOL_00111	6.93e-140	-	-	-	K	-	-	-	LysR substrate binding domain
HKEFDBOL_00112	4.04e-29	-	-	-	-	-	-	-	-
HKEFDBOL_00113	1.07e-287	-	-	-	S	-	-	-	Sterol carrier protein domain
HKEFDBOL_00114	1.76e-122	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HKEFDBOL_00115	2.01e-135	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
HKEFDBOL_00116	5.39e-84	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HKEFDBOL_00117	2.4e-297	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
HKEFDBOL_00118	3.03e-177	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HKEFDBOL_00119	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HKEFDBOL_00120	4.97e-64	-	-	-	S	-	-	-	Metal binding domain of Ada
HKEFDBOL_00121	5.01e-55	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HKEFDBOL_00122	4.39e-268	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HKEFDBOL_00123	2.89e-173	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKEFDBOL_00124	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKEFDBOL_00125	1.41e-155	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HKEFDBOL_00126	7.63e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HKEFDBOL_00127	1.14e-164	terC	-	-	P	-	-	-	Integral membrane protein TerC family
HKEFDBOL_00128	1.74e-75	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
HKEFDBOL_00129	2.38e-59	-	-	-	S	-	-	-	Bacterial PH domain
HKEFDBOL_00130	1.14e-119	-	-	-	S	-	-	-	Phage integrase family
HKEFDBOL_00131	6.65e-121	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HKEFDBOL_00132	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HKEFDBOL_00133	7e-131	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HKEFDBOL_00134	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKEFDBOL_00135	6.87e-277	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HKEFDBOL_00136	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HKEFDBOL_00137	3.74e-109	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HKEFDBOL_00138	6.02e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HKEFDBOL_00139	5.35e-223	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HKEFDBOL_00140	1.64e-198	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HKEFDBOL_00141	1.67e-79	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HKEFDBOL_00142	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HKEFDBOL_00143	1.61e-64	ylxQ	-	-	J	-	-	-	ribosomal protein
HKEFDBOL_00144	3.75e-63	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HKEFDBOL_00145	1.19e-259	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HKEFDBOL_00146	3.4e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HKEFDBOL_00147	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKEFDBOL_00148	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HKEFDBOL_00149	6.38e-254	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HKEFDBOL_00150	3.93e-181	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HKEFDBOL_00151	6.38e-178	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HKEFDBOL_00152	1.22e-121	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HKEFDBOL_00153	5.86e-168	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HKEFDBOL_00154	1.76e-235	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HKEFDBOL_00155	2.21e-180	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HKEFDBOL_00156	2.03e-251	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HKEFDBOL_00157	1.65e-151	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HKEFDBOL_00158	8.61e-296	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HKEFDBOL_00159	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HKEFDBOL_00160	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKEFDBOL_00161	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKEFDBOL_00162	1.3e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HKEFDBOL_00163	4.16e-51	ynzC	-	-	S	-	-	-	UPF0291 protein
HKEFDBOL_00164	9.86e-146	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HKEFDBOL_00165	7.18e-187	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HKEFDBOL_00166	1.15e-154	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
HKEFDBOL_00167	4.96e-270	-	-	-	S	-	-	-	SLAP domain
HKEFDBOL_00168	1.64e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HKEFDBOL_00169	1.63e-173	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HKEFDBOL_00170	2.08e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HKEFDBOL_00171	6.78e-60	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HKEFDBOL_00172	1.34e-289	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKEFDBOL_00173	5.56e-72	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HKEFDBOL_00174	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
HKEFDBOL_00175	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HKEFDBOL_00176	5.41e-172	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKEFDBOL_00177	2.1e-31	-	-	-	-	-	-	-	-
HKEFDBOL_00178	1.69e-06	-	-	-	-	-	-	-	-
HKEFDBOL_00179	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKEFDBOL_00180	4.69e-226	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HKEFDBOL_00181	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HKEFDBOL_00182	2.8e-160	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HKEFDBOL_00183	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HKEFDBOL_00184	2.46e-302	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HKEFDBOL_00185	7.81e-169	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
HKEFDBOL_00186	3.35e-55	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HKEFDBOL_00187	3.74e-182	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKEFDBOL_00188	7.92e-221	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKEFDBOL_00189	3.27e-229	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKEFDBOL_00190	1.21e-245	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKEFDBOL_00191	7.32e-46	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKEFDBOL_00192	3.69e-233	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HKEFDBOL_00193	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HKEFDBOL_00194	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HKEFDBOL_00195	8.29e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HKEFDBOL_00196	1.33e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HKEFDBOL_00197	2.29e-41	-	-	-	-	-	-	-	-
HKEFDBOL_00198	1.1e-159	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HKEFDBOL_00199	7.49e-154	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HKEFDBOL_00200	1.71e-208	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HKEFDBOL_00201	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HKEFDBOL_00202	3.28e-179	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HKEFDBOL_00203	7.82e-311	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HKEFDBOL_00204	1.27e-219	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HKEFDBOL_00205	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKEFDBOL_00206	2.37e-46	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HKEFDBOL_00207	5.97e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HKEFDBOL_00208	2.19e-100	-	-	-	S	-	-	-	ASCH
HKEFDBOL_00209	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HKEFDBOL_00210	7.22e-197	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HKEFDBOL_00211	6.44e-205	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HKEFDBOL_00212	1.53e-47	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKEFDBOL_00213	1.97e-248	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKEFDBOL_00214	7.19e-199	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKEFDBOL_00215	2.78e-85	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HKEFDBOL_00216	7.98e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HKEFDBOL_00217	2.11e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKEFDBOL_00218	2.14e-257	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HKEFDBOL_00219	7.95e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HKEFDBOL_00220	6.82e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HKEFDBOL_00221	5.24e-194	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKEFDBOL_00222	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HKEFDBOL_00224	2.07e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HKEFDBOL_00225	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HKEFDBOL_00226	8.21e-200	cinI	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
HKEFDBOL_00227	1.16e-269	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HKEFDBOL_00229	1.23e-227	lipA	-	-	I	-	-	-	Carboxylesterase family
HKEFDBOL_00230	1.82e-86	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
HKEFDBOL_00231	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HKEFDBOL_00232	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HKEFDBOL_00233	1.14e-189	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HKEFDBOL_00234	4.3e-66	-	-	-	-	-	-	-	-
HKEFDBOL_00235	8.51e-50	-	-	-	-	-	-	-	-
HKEFDBOL_00236	2.48e-80	-	-	-	S	-	-	-	Alpha beta hydrolase
HKEFDBOL_00237	6.78e-24	-	-	-	S	-	-	-	Alpha beta hydrolase
HKEFDBOL_00238	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HKEFDBOL_00239	2.88e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HKEFDBOL_00240	8.74e-62	-	-	-	-	-	-	-	-
HKEFDBOL_00241	6.79e-190	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HKEFDBOL_00242	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HKEFDBOL_00243	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HKEFDBOL_00244	4.22e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HKEFDBOL_00245	8.31e-313	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HKEFDBOL_00246	9.05e-231	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HKEFDBOL_00247	2.9e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HKEFDBOL_00248	8.81e-212	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HKEFDBOL_00249	1.56e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HKEFDBOL_00250	5.5e-154	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HKEFDBOL_00251	4.37e-132	-	-	-	GM	-	-	-	NmrA-like family
HKEFDBOL_00252	2.99e-07	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HKEFDBOL_00253	1.44e-57	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HKEFDBOL_00254	5.1e-139	-	-	-	L	-	-	-	PFAM Integrase catalytic
HKEFDBOL_00255	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HKEFDBOL_00256	3.23e-59	-	-	-	-	-	-	-	-
HKEFDBOL_00257	9.46e-159	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HKEFDBOL_00258	7.73e-199	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HKEFDBOL_00259	6.51e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HKEFDBOL_00260	5.01e-150	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HKEFDBOL_00261	7.68e-63	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HKEFDBOL_00262	1.43e-309	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HKEFDBOL_00263	2.44e-285	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKEFDBOL_00264	0.0	potE	-	-	E	-	-	-	Amino Acid
HKEFDBOL_00265	2.65e-107	-	-	-	S	-	-	-	Fic/DOC family
HKEFDBOL_00266	0.0	-	-	-	-	-	-	-	-
HKEFDBOL_00267	5.87e-110	-	-	-	-	-	-	-	-
HKEFDBOL_00268	1.92e-113	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
HKEFDBOL_00269	2.65e-89	-	-	-	O	-	-	-	OsmC-like protein
HKEFDBOL_00270	1.36e-266	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKEFDBOL_00271	3e-290	sptS	-	-	T	-	-	-	Histidine kinase
HKEFDBOL_00272	4e-31	dltr	-	-	K	-	-	-	response regulator
HKEFDBOL_00273	6.89e-93	-	-	-	K	ko:K03484	-	ko00000,ko03000	Periplasmic binding protein domain
HKEFDBOL_00274	2.14e-48	-	-	-	-	-	-	-	-
HKEFDBOL_00275	1.6e-251	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HKEFDBOL_00276	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HKEFDBOL_00277	4.16e-280	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HKEFDBOL_00278	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HKEFDBOL_00279	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HKEFDBOL_00280	1.48e-210	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HKEFDBOL_00281	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HKEFDBOL_00282	5.06e-184	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HKEFDBOL_00283	2.84e-240	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HKEFDBOL_00284	2.44e-210	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
HKEFDBOL_00285	5.55e-137	-	-	-	K	-	-	-	Transcriptional regulator, AbiEi antitoxin
HKEFDBOL_00286	4.05e-242	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
HKEFDBOL_00287	1.18e-95	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	domain protein
HKEFDBOL_00289	5.89e-316	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Adenine deaminase C-terminal domain
HKEFDBOL_00290	1.22e-195	-	-	-	P	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKEFDBOL_00291	4.48e-174	potA11	3.6.3.30	-	P	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HKEFDBOL_00292	7.05e-146	potC3	-	-	E	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKEFDBOL_00293	1.46e-48	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKEFDBOL_00294	1.59e-108	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HKEFDBOL_00295	2.58e-13	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HKEFDBOL_00296	6.9e-141	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HKEFDBOL_00297	4.42e-45	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
HKEFDBOL_00298	1.4e-74	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
HKEFDBOL_00299	6.48e-279	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HKEFDBOL_00300	1.48e-166	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKEFDBOL_00301	3.74e-70	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HKEFDBOL_00302	1.03e-112	nanK	-	-	GK	-	-	-	ROK family
HKEFDBOL_00303	2.65e-154	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
HKEFDBOL_00304	1.57e-84	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HKEFDBOL_00305	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKEFDBOL_00306	2.86e-13	-	-	-	K	ko:K15773	-	ko00000,ko02048,ko03000	peptidyl-tyrosine sulfation
HKEFDBOL_00307	1.28e-09	-	-	-	S	-	-	-	PFAM HicB family
HKEFDBOL_00308	2.81e-144	-	-	-	S	-	-	-	interspecies interaction between organisms
HKEFDBOL_00309	6.78e-47	-	-	-	-	-	-	-	-
HKEFDBOL_00313	2.09e-205	-	-	-	-	-	-	-	-
HKEFDBOL_00314	2.37e-219	-	-	-	-	-	-	-	-
HKEFDBOL_00315	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HKEFDBOL_00316	2.05e-286	ynbB	-	-	P	-	-	-	aluminum resistance
HKEFDBOL_00317	3.84e-216	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HKEFDBOL_00318	4.95e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HKEFDBOL_00319	1e-47	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HKEFDBOL_00320	3.25e-154	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
HKEFDBOL_00321	7.92e-126	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HKEFDBOL_00322	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HKEFDBOL_00323	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HKEFDBOL_00324	0.0	-	-	-	S	-	-	-	membrane
HKEFDBOL_00325	7.04e-218	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
HKEFDBOL_00326	9.43e-52	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HKEFDBOL_00327	2.74e-69	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
HKEFDBOL_00328	2.22e-60	hupB2	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HKEFDBOL_00329	1.49e-178	-	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
HKEFDBOL_00330	1.55e-201	isdF	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKEFDBOL_00331	2.07e-203	isdE	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HKEFDBOL_00332	7.04e-159	-	-	-	M	ko:K14193	ko05150,map05150	ko00000,ko00001	Iron Transport-associated domain
HKEFDBOL_00334	6.09e-121	-	-	-	-	-	-	-	-
HKEFDBOL_00335	1.29e-164	-	-	-	S	-	-	-	SLAP domain
HKEFDBOL_00336	6.91e-67	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HKEFDBOL_00337	2.04e-60	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
HKEFDBOL_00338	1.3e-175	-	-	-	S	-	-	-	Protein of unknown function (DUF3100)
HKEFDBOL_00339	5.84e-312	-	-	-	S	ko:K12941	-	ko00000,ko01002	Peptidase dimerisation domain
HKEFDBOL_00340	2.77e-292	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
HKEFDBOL_00341	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKEFDBOL_00342	1.76e-193	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKEFDBOL_00343	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
HKEFDBOL_00344	1.8e-34	-	-	-	-	-	-	-	-
HKEFDBOL_00345	5.5e-203	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HKEFDBOL_00346	8.21e-215	ldh3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
HKEFDBOL_00347	1.72e-92	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKEFDBOL_00348	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKEFDBOL_00349	2.9e-254	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HKEFDBOL_00350	1.3e-117	ydiM	-	-	G	-	-	-	Major facilitator superfamily
HKEFDBOL_00351	1.24e-169	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HKEFDBOL_00352	8.08e-117	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HKEFDBOL_00353	1.02e-67	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HKEFDBOL_00354	1.89e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKEFDBOL_00355	4.11e-150	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
HKEFDBOL_00356	1.8e-142	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
HKEFDBOL_00358	4.87e-81	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HKEFDBOL_00359	3.23e-172	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKEFDBOL_00360	5.58e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HKEFDBOL_00361	2.43e-216	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKEFDBOL_00362	2.08e-95	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
HKEFDBOL_00363	2.42e-69	-	-	-	S	-	-	-	Abi-like protein
HKEFDBOL_00364	7.24e-284	-	-	-	S	-	-	-	SLAP domain
HKEFDBOL_00365	9.04e-162	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKEFDBOL_00366	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKEFDBOL_00367	3.52e-163	csrR	-	-	K	-	-	-	response regulator
HKEFDBOL_00368	2.19e-125	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HKEFDBOL_00369	4.63e-275	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HKEFDBOL_00370	5.09e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HKEFDBOL_00371	9.22e-141	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HKEFDBOL_00372	1.77e-157	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HKEFDBOL_00373	5.03e-256	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HKEFDBOL_00374	6.85e-109	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HKEFDBOL_00375	3.01e-255	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
HKEFDBOL_00376	1.25e-192	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HKEFDBOL_00377	8.69e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HKEFDBOL_00378	9.64e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HKEFDBOL_00379	1.07e-93	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HKEFDBOL_00380	6.18e-123	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HKEFDBOL_00381	1.1e-128	-	-	-	E	ko:K02054	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKEFDBOL_00382	2.25e-30	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	domain protein
HKEFDBOL_00383	1.08e-217	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKEFDBOL_00384	9.29e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HKEFDBOL_00385	8.95e-70	-	-	-	K	-	-	-	LytTr DNA-binding domain
HKEFDBOL_00388	6.49e-137	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKEFDBOL_00389	5.59e-98	-	-	-	-	-	-	-	-
HKEFDBOL_00390	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKEFDBOL_00391	1.31e-215	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HKEFDBOL_00392	0.0	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
HKEFDBOL_00393	1.29e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HKEFDBOL_00394	2.16e-136	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HKEFDBOL_00395	7.81e-199	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HKEFDBOL_00396	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKEFDBOL_00397	1.98e-35	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HKEFDBOL_00398	2.53e-139	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HKEFDBOL_00399	1.33e-67	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HKEFDBOL_00400	2.43e-239	-	-	-	S	-	-	-	Bacteriocin helveticin-J
HKEFDBOL_00401	1.35e-11	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKEFDBOL_00402	1.15e-180	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
HKEFDBOL_00403	0.0	-	-	-	M	-	-	-	Peptidase family M1 domain
HKEFDBOL_00404	2.04e-226	-	-	-	S	-	-	-	SLAP domain
HKEFDBOL_00405	4.65e-278	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HKEFDBOL_00406	2.59e-313	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HKEFDBOL_00407	1.28e-156	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKEFDBOL_00408	1.35e-71	ytpP	-	-	CO	-	-	-	Thioredoxin
HKEFDBOL_00410	2.16e-163	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HKEFDBOL_00411	1.63e-281	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HKEFDBOL_00412	3.67e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKEFDBOL_00413	1.61e-101	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
HKEFDBOL_00414	1.2e-41	-	-	-	-	-	-	-	-
HKEFDBOL_00415	3.12e-196	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HKEFDBOL_00416	5.74e-96	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
HKEFDBOL_00417	3.94e-285	-	-	-	-	-	-	-	-
HKEFDBOL_00418	5.15e-35	-	-	-	-	-	-	-	-
HKEFDBOL_00419	9.67e-33	-	-	-	S	-	-	-	Domain of unknown function DUF1829
HKEFDBOL_00421	4.53e-239	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HKEFDBOL_00422	0.0	yhaN	-	-	L	-	-	-	AAA domain
HKEFDBOL_00423	4.24e-289	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HKEFDBOL_00424	8.43e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HKEFDBOL_00425	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HKEFDBOL_00426	1.21e-207	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HKEFDBOL_00427	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HKEFDBOL_00428	7.62e-134	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HKEFDBOL_00429	5.46e-182	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HKEFDBOL_00430	4.95e-164	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HKEFDBOL_00431	4.77e-248	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HKEFDBOL_00432	1.28e-226	-	-	-	S	-	-	-	PFAM Archaeal ATPase
HKEFDBOL_00433	1.08e-161	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
HKEFDBOL_00434	1.48e-139	-	-	-	EGP	-	-	-	Major Facilitator
HKEFDBOL_00435	9.16e-301	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HKEFDBOL_00436	7.84e-95	-	-	-	EGP	-	-	-	Major Facilitator
HKEFDBOL_00437	7.35e-45	-	-	-	-	-	-	-	-
HKEFDBOL_00440	3.3e-42	-	-	-	-	-	-	-	-
HKEFDBOL_00441	3.98e-97	-	-	-	M	-	-	-	LysM domain
HKEFDBOL_00443	4.12e-204	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HKEFDBOL_00444	2.29e-112	-	-	-	-	-	-	-	-
HKEFDBOL_00445	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKEFDBOL_00446	1.24e-232	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKEFDBOL_00447	5.07e-190	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKEFDBOL_00449	1.01e-98	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HKEFDBOL_00450	7.02e-36	-	-	-	-	-	-	-	-
HKEFDBOL_00451	1.32e-105	-	-	-	S	-	-	-	PFAM Archaeal ATPase
HKEFDBOL_00452	9.32e-107	-	-	-	S	-	-	-	PFAM Archaeal ATPase
HKEFDBOL_00453	6.03e-218	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HKEFDBOL_00454	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HKEFDBOL_00455	5.6e-129	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HKEFDBOL_00456	2.23e-197	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HKEFDBOL_00457	9.64e-307	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HKEFDBOL_00459	1.59e-61	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HKEFDBOL_00460	3.54e-300	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
HKEFDBOL_00461	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKEFDBOL_00462	2.69e-156	phoB	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HKEFDBOL_00463	6.07e-138	-	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HKEFDBOL_00464	4.66e-179	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKEFDBOL_00465	8.63e-195	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HKEFDBOL_00466	8.73e-205	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HKEFDBOL_00467	9.14e-187	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HKEFDBOL_00468	4.84e-42	-	-	-	-	-	-	-	-
HKEFDBOL_00469	3.11e-256	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKEFDBOL_00470	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HKEFDBOL_00471	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HKEFDBOL_00472	1.39e-156	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HKEFDBOL_00473	6.75e-216	-	-	-	K	-	-	-	LysR substrate binding domain
HKEFDBOL_00474	9.32e-109	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HKEFDBOL_00475	1.41e-51	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HKEFDBOL_00476	3.01e-294	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HKEFDBOL_00477	1.03e-206	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HKEFDBOL_00478	2.47e-153	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HKEFDBOL_00479	1.76e-165	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HKEFDBOL_00480	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HKEFDBOL_00481	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HKEFDBOL_00482	9.83e-236	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HKEFDBOL_00483	4.75e-302	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HKEFDBOL_00484	3.14e-27	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HKEFDBOL_00485	3.75e-168	-	-	-	K	-	-	-	rpiR family
HKEFDBOL_00486	7.66e-248	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HKEFDBOL_00487	3.48e-268	-	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKEFDBOL_00488	1.32e-151	-	-	-	S	-	-	-	Putative esterase
HKEFDBOL_00489	3.39e-154	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HKEFDBOL_00490	1.92e-102	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HKEFDBOL_00492	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
HKEFDBOL_00493	7.29e-287	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HKEFDBOL_00496	5.31e-211	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HKEFDBOL_00497	9.71e-47	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HKEFDBOL_00498	5.3e-32	-	-	-	-	-	-	-	-
HKEFDBOL_00499	4.26e-86	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HKEFDBOL_00500	1.38e-165	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HKEFDBOL_00501	9.06e-184	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HKEFDBOL_00502	1.44e-53	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HKEFDBOL_00503	4.98e-37	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HKEFDBOL_00504	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HKEFDBOL_00505	1.23e-129	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HKEFDBOL_00506	3.2e-143	-	-	-	S	-	-	-	SNARE associated Golgi protein
HKEFDBOL_00507	2.52e-194	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKEFDBOL_00508	1.15e-201	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HKEFDBOL_00509	9.75e-20	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
HKEFDBOL_00510	1.41e-37	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
HKEFDBOL_00511	2.35e-117	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HKEFDBOL_00512	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HKEFDBOL_00513	9.28e-290	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
HKEFDBOL_00514	1.2e-220	-	-	-	-	-	-	-	-
HKEFDBOL_00515	1.86e-31	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKEFDBOL_00517	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HKEFDBOL_00518	1.53e-127	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKEFDBOL_00519	9.18e-187	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HKEFDBOL_00520	2.62e-199	epsV	-	-	S	-	-	-	glycosyl transferase family 2
HKEFDBOL_00521	5.29e-164	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HKEFDBOL_00522	1.89e-205	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HKEFDBOL_00523	1.4e-207	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HKEFDBOL_00524	1.23e-309	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKEFDBOL_00525	0.0	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
HKEFDBOL_00526	3.25e-186	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKEFDBOL_00527	1.64e-202	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
HKEFDBOL_00528	5.26e-259	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKEFDBOL_00529	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKEFDBOL_00530	7.24e-204	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HKEFDBOL_00531	1.29e-230	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
HKEFDBOL_00532	5.11e-203	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HKEFDBOL_00533	2.23e-150	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HKEFDBOL_00534	2.94e-74	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HKEFDBOL_00535	7.8e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HKEFDBOL_00536	3.85e-180	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HKEFDBOL_00537	4.53e-11	-	-	-	-	-	-	-	-
HKEFDBOL_00538	1.02e-75	-	-	-	-	-	-	-	-
HKEFDBOL_00539	2.62e-69	-	-	-	-	-	-	-	-
HKEFDBOL_00541	4.4e-165	-	-	-	S	-	-	-	PAS domain
HKEFDBOL_00542	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
HKEFDBOL_00543	1.28e-228	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HKEFDBOL_00544	1.75e-168	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HKEFDBOL_00545	2.37e-242	-	-	-	T	-	-	-	GHKL domain
HKEFDBOL_00546	2.88e-98	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HKEFDBOL_00547	5.59e-109	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HKEFDBOL_00548	8e-108	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HKEFDBOL_00549	8.64e-85	yybA	-	-	K	-	-	-	Transcriptional regulator
HKEFDBOL_00550	2.91e-83	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HKEFDBOL_00551	1.13e-201	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HKEFDBOL_00552	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKEFDBOL_00553	1.04e-80	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HKEFDBOL_00554	1.45e-36	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HKEFDBOL_00555	2.15e-299	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HKEFDBOL_00556	1.24e-75	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HKEFDBOL_00557	1.48e-134	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKEFDBOL_00558	1.95e-218	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HKEFDBOL_00559	1.88e-125	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HKEFDBOL_00560	1.36e-96	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HKEFDBOL_00561	7.09e-184	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HKEFDBOL_00562	6.89e-136	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
HKEFDBOL_00563	7.06e-138	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HKEFDBOL_00564	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HKEFDBOL_00565	1.47e-158	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HKEFDBOL_00566	7.53e-163	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
HKEFDBOL_00567	1.87e-308	-	-	-	S	-	-	-	response to antibiotic
HKEFDBOL_00568	1.34e-162	-	-	-	-	-	-	-	-
HKEFDBOL_00569	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HKEFDBOL_00570	6.28e-87	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HKEFDBOL_00571	1.42e-57	-	-	-	-	-	-	-	-
HKEFDBOL_00572	4.71e-239	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
HKEFDBOL_00573	1.43e-176	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
HKEFDBOL_00574	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
HKEFDBOL_00575	2.15e-197	-	-	-	-	-	-	-	-
HKEFDBOL_00576	3.32e-13	-	-	-	-	-	-	-	-
HKEFDBOL_00577	6.57e-113	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HKEFDBOL_00578	1.18e-136	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HKEFDBOL_00581	3.67e-92	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HKEFDBOL_00582	1.36e-136	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HKEFDBOL_00583	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HKEFDBOL_00584	6.38e-95	-	-	-	L	-	-	-	Transposase DDE domain
HKEFDBOL_00585	5.7e-69	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
HKEFDBOL_00587	3.49e-50	-	-	-	-	-	-	-	-
HKEFDBOL_00588	1.76e-233	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKEFDBOL_00589	8.37e-161	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKEFDBOL_00590	1.3e-176	-	-	-	-	-	-	-	-
HKEFDBOL_00591	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HKEFDBOL_00592	1.01e-170	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKEFDBOL_00593	7.36e-291	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HKEFDBOL_00594	2.43e-263	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HKEFDBOL_00595	2.45e-164	-	-	-	-	-	-	-	-
HKEFDBOL_00596	6.89e-258	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HKEFDBOL_00597	2.23e-166	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HKEFDBOL_00598	4.67e-200	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKEFDBOL_00599	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
HKEFDBOL_00600	3.75e-278	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HKEFDBOL_00601	5.18e-141	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
HKEFDBOL_00602	3.16e-184	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HKEFDBOL_00603	1.93e-155	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HKEFDBOL_00604	8.55e-191	epsB	-	-	M	-	-	-	biosynthesis protein
HKEFDBOL_00605	1.53e-245	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HKEFDBOL_00606	2.09e-63	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
HKEFDBOL_00607	9.52e-56	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HKEFDBOL_00609	2.01e-286	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKEFDBOL_00610	2.08e-222	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HKEFDBOL_00612	3.01e-54	-	-	-	-	-	-	-	-
HKEFDBOL_00613	1.73e-167	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
HKEFDBOL_00614	1.28e-174	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HKEFDBOL_00615	1.47e-114	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
HKEFDBOL_00616	4.26e-115	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
HKEFDBOL_00617	4.52e-56	-	-	-	-	-	-	-	-
HKEFDBOL_00618	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
HKEFDBOL_00619	8.77e-144	-	-	-	-	-	-	-	-
HKEFDBOL_00620	5.48e-283	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
HKEFDBOL_00621	4.75e-101	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
HKEFDBOL_00622	1.96e-226	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKEFDBOL_00623	1.16e-101	-	-	-	-	-	-	-	-
HKEFDBOL_00624	1.58e-143	-	-	-	S	-	-	-	Peptidase_C39 like family
HKEFDBOL_00625	7.36e-109	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HKEFDBOL_00626	7.35e-174	-	-	-	S	-	-	-	Putative threonine/serine exporter
HKEFDBOL_00627	0.0	-	-	-	S	-	-	-	ABC transporter
HKEFDBOL_00628	2.52e-76	-	-	-	-	-	-	-	-
HKEFDBOL_00629	8.69e-93	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HKEFDBOL_00630	5.49e-46	-	-	-	-	-	-	-	-
HKEFDBOL_00631	7.2e-40	-	-	-	-	-	-	-	-
HKEFDBOL_00632	2.33e-143	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HKEFDBOL_00633	5.74e-256	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HKEFDBOL_00634	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HKEFDBOL_00635	7.27e-42	-	-	-	-	-	-	-	-
HKEFDBOL_00636	1.47e-91	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Prophage maintenance system killer protein
HKEFDBOL_00639	4.61e-37	-	-	-	S	-	-	-	Enterocin A Immunity
HKEFDBOL_00642	1.13e-35	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HKEFDBOL_00643	0.000868	-	-	-	-	-	-	-	-
HKEFDBOL_00644	2.04e-277	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HKEFDBOL_00645	6.6e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HKEFDBOL_00646	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HKEFDBOL_00647	1.59e-172	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HKEFDBOL_00648	1.63e-152	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HKEFDBOL_00649	9.9e-209	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HKEFDBOL_00650	4.47e-56	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HKEFDBOL_00651	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HKEFDBOL_00652	2.18e-215	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HKEFDBOL_00653	3.14e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HKEFDBOL_00654	6.39e-279	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKEFDBOL_00655	3.09e-212	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKEFDBOL_00656	3.41e-88	-	-	-	-	-	-	-	-
HKEFDBOL_00657	2.52e-32	-	-	-	-	-	-	-	-
HKEFDBOL_00658	6.32e-42	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
HKEFDBOL_00659	4.74e-107	-	-	-	-	-	-	-	-
HKEFDBOL_00660	7.87e-30	-	-	-	-	-	-	-	-
HKEFDBOL_00664	5.02e-180	blpT	-	-	-	-	-	-	-
HKEFDBOL_00665	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HKEFDBOL_00666	2.08e-164	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HKEFDBOL_00667	8.83e-170	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HKEFDBOL_00668	1.89e-23	-	-	-	-	-	-	-	-
HKEFDBOL_00669	0.0	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
HKEFDBOL_00670	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HKEFDBOL_00671	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HKEFDBOL_00672	4.48e-34	-	-	-	-	-	-	-	-
HKEFDBOL_00673	1.07e-35	-	-	-	-	-	-	-	-
HKEFDBOL_00674	1.95e-45	-	-	-	-	-	-	-	-
HKEFDBOL_00675	6.94e-70	-	-	-	S	-	-	-	Enterocin A Immunity
HKEFDBOL_00676	7.79e-186	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HKEFDBOL_00677	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HKEFDBOL_00678	9.28e-271	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HKEFDBOL_00679	8.32e-157	vanR	-	-	K	-	-	-	response regulator
HKEFDBOL_00681	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HKEFDBOL_00682	1.67e-32	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HKEFDBOL_00683	1.68e-179	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HKEFDBOL_00684	1.22e-190	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HKEFDBOL_00685	3.93e-176	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HKEFDBOL_00686	6.88e-257	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HKEFDBOL_00687	1.1e-59	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HKEFDBOL_00688	1.49e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HKEFDBOL_00689	4.99e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HKEFDBOL_00690	2.91e-191	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HKEFDBOL_00691	3.66e-166	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HKEFDBOL_00692	2.99e-75	cvpA	-	-	S	-	-	-	Colicin V production protein
HKEFDBOL_00694	5.24e-230	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKEFDBOL_00695	9.48e-194	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HKEFDBOL_00696	2.58e-126	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HKEFDBOL_00697	3.41e-125	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HKEFDBOL_00698	1.25e-143	-	-	-	K	-	-	-	WHG domain
HKEFDBOL_00699	2.63e-50	-	-	-	-	-	-	-	-
HKEFDBOL_00700	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKEFDBOL_00701	2.12e-132	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKEFDBOL_00702	1.05e-233	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HKEFDBOL_00703	1.45e-119	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKEFDBOL_00704	2.75e-143	-	-	-	G	-	-	-	phosphoglycerate mutase
HKEFDBOL_00705	9.79e-181	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HKEFDBOL_00706	1.45e-183	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HKEFDBOL_00707	5.5e-155	-	-	-	-	-	-	-	-
HKEFDBOL_00708	9.18e-202	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HKEFDBOL_00709	2.07e-250	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HKEFDBOL_00710	2.61e-23	-	-	-	-	-	-	-	-
HKEFDBOL_00711	1.16e-123	-	-	-	S	-	-	-	membrane
HKEFDBOL_00712	5.3e-92	-	-	-	K	-	-	-	LytTr DNA-binding domain
HKEFDBOL_00713	6.93e-34	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HKEFDBOL_00714	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HKEFDBOL_00715	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HKEFDBOL_00716	2.2e-79	lysM	-	-	M	-	-	-	LysM domain
HKEFDBOL_00717	7.62e-223	-	-	-	-	-	-	-	-
HKEFDBOL_00718	6.74e-212	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HKEFDBOL_00719	1.27e-58	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HKEFDBOL_00720	1.86e-114	ymdB	-	-	S	-	-	-	Macro domain protein
HKEFDBOL_00725	4.73e-84	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKEFDBOL_00726	1.39e-197	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKEFDBOL_00727	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKEFDBOL_00728	2.73e-282	-	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKEFDBOL_00729	2.85e-266	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKEFDBOL_00730	7.7e-149	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HKEFDBOL_00731	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HKEFDBOL_00732	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HKEFDBOL_00733	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HKEFDBOL_00734	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
HKEFDBOL_00735	6.36e-230	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HKEFDBOL_00736	4.24e-46	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HKEFDBOL_00737	3.47e-19	-	-	-	-	ko:K07473	-	ko00000,ko02048	-
HKEFDBOL_00738	1e-131	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HKEFDBOL_00739	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HKEFDBOL_00740	3.66e-186	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HKEFDBOL_00741	1.74e-248	-	-	-	G	-	-	-	Transmembrane secretion effector
HKEFDBOL_00742	5.63e-171	-	-	-	V	-	-	-	ABC transporter transmembrane region
HKEFDBOL_00743	3.65e-285	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HKEFDBOL_00744	1.83e-91	-	-	-	V	-	-	-	ABC transporter transmembrane region
HKEFDBOL_00745	6.69e-84	-	-	-	L	-	-	-	RelB antitoxin
HKEFDBOL_00746	1.51e-168	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HKEFDBOL_00747	8.6e-108	-	-	-	M	-	-	-	NlpC/P60 family
HKEFDBOL_00750	1.02e-200	-	-	-	-	-	-	-	-
HKEFDBOL_00751	1.03e-07	-	-	-	-	-	-	-	-
HKEFDBOL_00752	5.51e-47	-	-	-	-	-	-	-	-
HKEFDBOL_00753	4.48e-206	-	-	-	EG	-	-	-	EamA-like transporter family
HKEFDBOL_00754	3.18e-209	-	-	-	EG	-	-	-	EamA-like transporter family
HKEFDBOL_00755	3.75e-178	yicL	-	-	EG	-	-	-	EamA-like transporter family
HKEFDBOL_00756	1.32e-137	-	-	-	-	-	-	-	-
HKEFDBOL_00757	9.07e-143	-	-	-	-	-	-	-	-
HKEFDBOL_00758	1.84e-238	-	-	-	S	-	-	-	DUF218 domain
HKEFDBOL_00759	0.0	yheS_2	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
HKEFDBOL_00760	6.77e-111	-	-	-	-	-	-	-	-
HKEFDBOL_00761	1.09e-74	-	-	-	-	-	-	-	-
HKEFDBOL_00762	7.26e-35	-	-	-	S	-	-	-	Protein conserved in bacteria
HKEFDBOL_00763	2.27e-71	-	-	-	S	-	-	-	protein encoded in hypervariable junctions of pilus gene clusters
HKEFDBOL_00764	1.01e-38	-	-	-	S	-	-	-	HicA toxin of bacterial toxin-antitoxin,
HKEFDBOL_00765	2.62e-95	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKEFDBOL_00766	7.13e-313	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HKEFDBOL_00767	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HKEFDBOL_00768	1.35e-238	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKEFDBOL_00771	1.84e-263	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
HKEFDBOL_00772	5.12e-242	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HKEFDBOL_00773	6.45e-291	-	-	-	E	-	-	-	amino acid
HKEFDBOL_00774	6.65e-179	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HKEFDBOL_00776	1.95e-221	-	-	-	V	-	-	-	HNH endonuclease
HKEFDBOL_00777	6.36e-173	-	-	-	S	-	-	-	PFAM Archaeal ATPase
HKEFDBOL_00778	5.27e-314	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HKEFDBOL_00779	2.58e-310	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HKEFDBOL_00780	5.08e-149	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HKEFDBOL_00781	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
HKEFDBOL_00782	7.86e-212	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKEFDBOL_00783	3.09e-304	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKEFDBOL_00784	1.68e-161	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKEFDBOL_00785	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HKEFDBOL_00786	1.96e-49	-	-	-	-	-	-	-	-
HKEFDBOL_00787	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HKEFDBOL_00788	1.34e-183	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HKEFDBOL_00789	2.5e-172	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HKEFDBOL_00790	1.97e-227	pbpX2	-	-	V	-	-	-	Beta-lactamase
HKEFDBOL_00791	5.44e-315	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HKEFDBOL_00792	4.98e-48	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKEFDBOL_00793	2.95e-304	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HKEFDBOL_00794	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKEFDBOL_00795	1.3e-26	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HKEFDBOL_00796	1.42e-58	-	-	-	-	-	-	-	-
HKEFDBOL_00797	5.11e-265	-	-	-	S	-	-	-	Membrane
HKEFDBOL_00798	3.41e-107	ykuL	-	-	S	-	-	-	(CBS) domain
HKEFDBOL_00799	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HKEFDBOL_00800	5.71e-263	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
HKEFDBOL_00801	2.49e-63	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HKEFDBOL_00802	1.68e-55	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
HKEFDBOL_00803	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
HKEFDBOL_00804	1.91e-200	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKEFDBOL_00805	1.05e-67	-	-	-	-	-	-	-	-
HKEFDBOL_00806	3.62e-202	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HKEFDBOL_00807	1.49e-141	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
HKEFDBOL_00808	3.43e-155	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKEFDBOL_00809	5.14e-248	-	-	-	S	-	-	-	DUF218 domain
HKEFDBOL_00810	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKEFDBOL_00811	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HKEFDBOL_00812	5.9e-130	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HKEFDBOL_00813	1.19e-31	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
HKEFDBOL_00814	1.06e-203	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
HKEFDBOL_00815	4.57e-232	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
HKEFDBOL_00816	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
HKEFDBOL_00817	8.8e-262	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HKEFDBOL_00818	2.1e-220	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HKEFDBOL_00819	3.08e-205	-	-	-	S	-	-	-	Aldo/keto reductase family
HKEFDBOL_00820	1.15e-173	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HKEFDBOL_00821	9.85e-154	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
HKEFDBOL_00822	1.06e-159	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
HKEFDBOL_00823	6.64e-94	-	-	-	-	-	-	-	-
HKEFDBOL_00824	2.56e-179	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HKEFDBOL_00825	9.69e-292	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HKEFDBOL_00826	3.85e-97	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKEFDBOL_00827	4.03e-75	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKEFDBOL_00828	8.34e-116	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKEFDBOL_00829	3.31e-154	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKEFDBOL_00830	3.82e-294	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HKEFDBOL_00831	3.69e-54	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
HKEFDBOL_00832	5.05e-11	-	-	-	-	-	-	-	-
HKEFDBOL_00833	3.58e-61	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
HKEFDBOL_00835	4.06e-108	yneE	-	-	K	-	-	-	Transcriptional regulator
HKEFDBOL_00836	1.92e-80	yneE	-	-	K	-	-	-	Transcriptional regulator
HKEFDBOL_00837	9.01e-287	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
HKEFDBOL_00838	8.73e-187	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HKEFDBOL_00839	1.28e-292	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HKEFDBOL_00840	7.19e-77	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKEFDBOL_00841	7.23e-50	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HKEFDBOL_00842	3.61e-212	-	-	-	V	-	-	-	ABC transporter transmembrane region
HKEFDBOL_00843	1.26e-176	-	-	-	-	-	-	-	-
HKEFDBOL_00847	2.23e-48	-	-	-	-	-	-	-	-
HKEFDBOL_00848	1.99e-73	-	-	-	S	-	-	-	Cupredoxin-like domain
HKEFDBOL_00849	3.27e-58	-	-	-	S	-	-	-	Cupredoxin-like domain
HKEFDBOL_00850	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HKEFDBOL_00851	6.63e-147	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HKEFDBOL_00852	3.14e-137	-	-	-	-	-	-	-	-
HKEFDBOL_00853	1.83e-316	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
HKEFDBOL_00854	6.46e-27	-	-	-	-	-	-	-	-
HKEFDBOL_00855	3.91e-269	-	-	-	-	-	-	-	-
HKEFDBOL_00856	6.57e-175	-	-	-	S	-	-	-	SLAP domain
HKEFDBOL_00857	1.14e-154	-	-	-	S	-	-	-	SLAP domain
HKEFDBOL_00858	4.54e-135	-	-	-	S	-	-	-	Bacteriocin helveticin-J
HKEFDBOL_00859	2.35e-58	-	-	-	-	-	-	-	-
HKEFDBOL_00860	8.29e-76	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKEFDBOL_00861	1.98e-41	-	-	-	E	-	-	-	Zn peptidase
HKEFDBOL_00862	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HKEFDBOL_00864	1.42e-74	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HKEFDBOL_00871	5.44e-20	-	-	-	-	-	-	-	-
HKEFDBOL_00872	3.02e-08	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
HKEFDBOL_00880	2.16e-240	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
HKEFDBOL_00886	5.41e-13	cll	-	-	-	-	-	-	-
HKEFDBOL_00894	5.16e-23	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3850)
HKEFDBOL_00897	1.2e-211	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HKEFDBOL_00899	8.97e-41	-	-	-	O	-	-	-	AAA ATPase central domain protein
HKEFDBOL_00903	1.02e-12	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKEFDBOL_00905	1.48e-23	-	-	-	-	-	-	-	-
HKEFDBOL_00906	6.58e-310	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HKEFDBOL_00907	5.48e-112	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HKEFDBOL_00908	9.63e-16	-	-	-	-	-	-	-	-
HKEFDBOL_00914	1.14e-115	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
HKEFDBOL_00915	7.6e-113	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKEFDBOL_00916	3.56e-191	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HKEFDBOL_00917	2.65e-108	usp5	-	-	T	-	-	-	universal stress protein
HKEFDBOL_00919	1.78e-212	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HKEFDBOL_00920	6.34e-180	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HKEFDBOL_00921	1.91e-168	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKEFDBOL_00922	1.29e-190	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKEFDBOL_00923	7.05e-103	-	-	-	L	-	-	-	COG3385 FOG Transposase and inactivated derivatives
HKEFDBOL_00924	6.06e-58	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HKEFDBOL_00925	6.27e-161	-	-	-	L	-	-	-	Transposase
HKEFDBOL_00933	5.86e-69	-	-	-	S	-	-	-	Phage capsid family
HKEFDBOL_00934	4.37e-110	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HKEFDBOL_00935	2.23e-169	-	-	-	S	-	-	-	Phage portal protein
HKEFDBOL_00937	2.23e-261	-	-	-	S	-	-	-	Phage Terminase
HKEFDBOL_00938	1.57e-61	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
HKEFDBOL_00939	6.84e-10	-	-	-	S	-	-	-	HicA toxin of bacterial toxin-antitoxin,
HKEFDBOL_00940	1.2e-71	-	-	-	L	-	-	-	Phage terminase, small subunit
HKEFDBOL_00945	1.25e-54	-	-	-	S	-	-	-	VRR-NUC domain
HKEFDBOL_00951	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
HKEFDBOL_00954	2.27e-187	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HKEFDBOL_00956	2.83e-90	-	-	-	S	-	-	-	AAA domain
HKEFDBOL_00963	1.7e-23	-	-	-	-	-	-	-	-
HKEFDBOL_00966	1.29e-37	-	-	-	-	-	-	-	-
HKEFDBOL_00967	4.01e-62	-	-	-	K	-	-	-	ORF6N domain
HKEFDBOL_00968	6.76e-57	-	-	-	K	-	-	-	ORF6N domain
HKEFDBOL_00969	1.28e-23	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKEFDBOL_00970	1.63e-24	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HKEFDBOL_00982	1.47e-34	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
HKEFDBOL_00983	7.82e-80	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
HKEFDBOL_00984	4.19e-160	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HKEFDBOL_00985	2.56e-45	-	-	-	M	-	-	-	LysM domain protein
HKEFDBOL_00986	5.18e-193	-	-	-	KL	-	-	-	domain protein
HKEFDBOL_00987	3.52e-42	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HKEFDBOL_00989	6.4e-136	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
HKEFDBOL_00990	2.89e-18	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HKEFDBOL_00993	1.76e-36	-	-	-	S	ko:K06915	-	ko00000	cog cog0433
HKEFDBOL_00994	2.41e-39	-	-	-	-	-	-	-	-
HKEFDBOL_00997	1.3e-64	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKEFDBOL_00998	0.0	-	-	-	L	-	-	-	Transposase DDE domain
HKEFDBOL_00999	1.18e-235	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
HKEFDBOL_01001	1.87e-220	-	-	-	L	-	-	-	COG3385 FOG Transposase and inactivated derivatives
HKEFDBOL_01002	5.61e-138	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HKEFDBOL_01003	5.18e-109	-	-	-	-	-	-	-	-
HKEFDBOL_01004	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HKEFDBOL_01005	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HKEFDBOL_01006	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
HKEFDBOL_01007	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HKEFDBOL_01008	1.35e-180	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKEFDBOL_01009	5.8e-131	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HKEFDBOL_01010	2.19e-292	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HKEFDBOL_01011	1.62e-277	yqjV	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKEFDBOL_01012	5.34e-77	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
HKEFDBOL_01013	1.01e-33	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HKEFDBOL_01016	1.65e-38	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
HKEFDBOL_01017	2.45e-108	-	-	-	S	-	-	-	N-acetylmuramoyl-L-alanine amidase activity
HKEFDBOL_01018	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HKEFDBOL_01022	1.79e-85	-	-	-	K	-	-	-	LytTr DNA-binding domain
HKEFDBOL_01023	6.11e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HKEFDBOL_01030	3.9e-59	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
HKEFDBOL_01031	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HKEFDBOL_01032	3.87e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HKEFDBOL_01033	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HKEFDBOL_01034	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HKEFDBOL_01035	6.55e-97	-	-	-	-	-	-	-	-
HKEFDBOL_01036	3.75e-48	-	-	-	S	-	-	-	PFAM Archaeal ATPase
HKEFDBOL_01038	4.53e-76	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HKEFDBOL_01039	3.61e-60	-	-	-	-	-	-	-	-
HKEFDBOL_01040	9.07e-51	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
HKEFDBOL_01041	1.39e-53	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKEFDBOL_01042	1.44e-164	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKEFDBOL_01043	2.47e-104	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HKEFDBOL_01044	1.5e-93	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HKEFDBOL_01045	1.27e-20	-	-	-	-	-	-	-	-
HKEFDBOL_01046	1.75e-26	-	-	-	S	-	-	-	Phage uncharacterised protein (Phage_XkdX)
HKEFDBOL_01049	6.3e-25	-	-	-	-	-	-	-	-
HKEFDBOL_01050	3.62e-40	-	-	-	-	-	-	-	-
HKEFDBOL_01052	9e-132	-	-	-	L	-	-	-	Integrase
HKEFDBOL_01053	4.02e-91	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
HKEFDBOL_01054	5.32e-42	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
HKEFDBOL_01055	1.39e-143	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HKEFDBOL_01064	1.61e-155	-	-	-	S	-	-	-	Phage minor structural protein
HKEFDBOL_01066	2.77e-25	-	-	-	-	-	-	-	-
HKEFDBOL_01067	1.21e-40	-	-	-	-	-	-	-	-
HKEFDBOL_01068	1.05e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HKEFDBOL_01069	1.82e-134	-	-	-	S	-	-	-	SLAP domain
HKEFDBOL_01070	6.87e-27	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HKEFDBOL_01072	5.32e-190	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HKEFDBOL_01074	8.49e-100	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HKEFDBOL_01075	2.85e-54	-	-	-	-	-	-	-	-
HKEFDBOL_01077	2.52e-06	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
HKEFDBOL_01078	0.0	-	3.6.3.6	-	P	ko:K01535	ko00190,map00190	ko00000,ko00001,ko01000	Cation transporter/ATPase, N-terminus
HKEFDBOL_01079	4.97e-45	-	3.6.3.2, 3.6.3.6, 3.6.3.8	-	P	ko:K01531,ko:K01535,ko:K01537,ko:K12952	ko00190,map00190	ko00000,ko00001,ko01000	cation transport ATPase
HKEFDBOL_01081	3.28e-101	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HKEFDBOL_01082	1.41e-97	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HKEFDBOL_01083	1.47e-70	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HKEFDBOL_01084	5.38e-184	-	-	-	K	-	-	-	LysR substrate binding domain
HKEFDBOL_01085	4.12e-205	pct	2.8.3.1	-	I	ko:K01026	ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120	ko00000,ko00001,ko01000	Coenzyme A transferase
HKEFDBOL_01086	8.45e-102	pct	2.8.3.1	-	I	ko:K01026	ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120	ko00000,ko00001,ko01000	Coenzyme A transferase
HKEFDBOL_01087	4.36e-181	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKEFDBOL_01089	1.2e-71	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HKEFDBOL_01090	1.3e-162	-	-	-	S	-	-	-	SLAP domain
HKEFDBOL_01092	7.88e-59	-	-	-	L	-	-	-	Transposase, IS116 IS110 IS902 family
HKEFDBOL_01093	5.48e-103	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HKEFDBOL_01094	3.77e-144	aapA	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HKEFDBOL_01096	7.24e-191	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HKEFDBOL_01097	1.08e-229	-	-	-	L	-	-	-	DDE superfamily endonuclease
HKEFDBOL_01098	3.43e-175	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKEFDBOL_01099	3.93e-118	-	-	-	G	-	-	-	FGGY family of carbohydrate kinases, C-terminal domain
HKEFDBOL_01100	2.59e-219	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HKEFDBOL_01101	5.21e-29	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKEFDBOL_01102	1.14e-44	-	2.7.1.200	-	GT	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKEFDBOL_01103	1.75e-145	-	-	-	G	-	-	-	Fructose-bisphosphate aldolase class-II
HKEFDBOL_01104	4.24e-78	farR	-	-	K	-	-	-	Helix-turn-helix domain
HKEFDBOL_01106	1.87e-55	-	-	-	S	-	-	-	ASCH domain
HKEFDBOL_01107	6.09e-130	-	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	sulfate reduction
HKEFDBOL_01109	1.24e-40	-	-	-	-	-	-	-	-
HKEFDBOL_01110	9.09e-143	-	-	-	K	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
HKEFDBOL_01111	1.26e-108	-	-	-	L	-	-	-	transposase activity
HKEFDBOL_01112	1.01e-270	-	-	-	S	ko:K06909	-	ko00000	Terminase RNAseH like domain
HKEFDBOL_01113	4.77e-269	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HKEFDBOL_01114	1.87e-214	-	-	-	S	-	-	-	Phage minor capsid protein 2
HKEFDBOL_01116	1.89e-53	-	-	-	S	-	-	-	Phage minor structural protein GP20
HKEFDBOL_01117	6.19e-195	gpG	-	-	-	-	-	-	-
HKEFDBOL_01118	6.65e-58	-	-	-	-	-	-	-	-
HKEFDBOL_01119	2.27e-52	-	-	-	S	-	-	-	Minor capsid protein
HKEFDBOL_01120	1.92e-41	-	-	-	S	-	-	-	Minor capsid protein
HKEFDBOL_01121	1.67e-67	-	-	-	S	-	-	-	Minor capsid protein from bacteriophage
HKEFDBOL_01122	1.61e-105	-	-	-	N	-	-	-	domain, Protein
HKEFDBOL_01123	2.11e-45	-	-	-	-	-	-	-	-
HKEFDBOL_01124	4.82e-110	-	-	-	S	-	-	-	Bacteriophage Gp15 protein
HKEFDBOL_01125	0.0	-	-	-	D	-	-	-	domain protein
HKEFDBOL_01126	2.14e-138	-	-	-	S	-	-	-	phage tail
HKEFDBOL_01127	0.0	-	-	-	S	-	-	-	Phage minor structural protein
HKEFDBOL_01130	7.7e-126	-	-	-	L	-	-	-	Helix-turn-helix domain
HKEFDBOL_01131	1.47e-286	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HKEFDBOL_01132	8.93e-233	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
HKEFDBOL_01133	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HKEFDBOL_01134	2.47e-138	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HKEFDBOL_01135	1.68e-207	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HKEFDBOL_01136	1.98e-168	-	-	-	-	-	-	-	-
HKEFDBOL_01137	1.72e-149	-	-	-	-	-	-	-	-
HKEFDBOL_01138	4.51e-171	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKEFDBOL_01139	5.18e-128	-	-	-	G	-	-	-	Aldose 1-epimerase
HKEFDBOL_01140	2.92e-258	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HKEFDBOL_01141	1.03e-145	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HKEFDBOL_01142	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
HKEFDBOL_01151	1.41e-47	-	-	-	L	-	-	-	HNH endonuclease
HKEFDBOL_01154	1.38e-220	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
HKEFDBOL_01156	2.43e-126	-	-	-	S	-	-	-	Phage portal protein
HKEFDBOL_01157	1.83e-65	-	-	-	S	-	-	-	Clp protease
HKEFDBOL_01158	2.07e-108	-	-	-	S	-	-	-	Phage capsid family
HKEFDBOL_01161	3.91e-38	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HKEFDBOL_01166	3.51e-160	-	-	-	D	-	-	-	domain protein
HKEFDBOL_01168	2.88e-203	-	-	-	S	-	-	-	Phage minor structural protein
HKEFDBOL_01173	1.44e-132	-	-	-	-	-	-	-	-
HKEFDBOL_01174	0.0	-	-	-	U	-	-	-	Psort location Cytoplasmic, score
HKEFDBOL_01175	1.03e-138	-	-	-	-	-	-	-	-
HKEFDBOL_01183	8.2e-46	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HKEFDBOL_01184	1.84e-06	-	-	-	S	-	-	-	Antirestriction protein (ArdA)
HKEFDBOL_01189	5.76e-06	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HKEFDBOL_01190	1.28e-108	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HKEFDBOL_01196	9.07e-91	-	-	-	-	-	-	-	-
HKEFDBOL_01198	1.32e-263	-	-	-	M	-	-	-	Psort location Cellwall, score
HKEFDBOL_01199	5.88e-12	-	-	-	S	-	-	-	SLAP domain
HKEFDBOL_01203	9.57e-108	-	-	-	-	ko:K18640	-	ko00000,ko04812	-
HKEFDBOL_01206	2.16e-155	-	-	-	U	-	-	-	TraM recognition site of TraD and TraG
HKEFDBOL_01212	1.57e-36	-	-	-	-	-	-	-	-
HKEFDBOL_01216	6.46e-51	-	-	-	M	-	-	-	Bacteriophage peptidoglycan hydrolase
HKEFDBOL_01218	8.09e-11	-	-	-	M	-	-	-	MucBP domain
HKEFDBOL_01222	5.86e-73	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HKEFDBOL_01225	2.4e-08	-	-	-	L	-	-	-	Initiator Replication protein
HKEFDBOL_01226	3.15e-56	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
HKEFDBOL_01227	1.94e-104	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HKEFDBOL_01237	1.23e-285	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HKEFDBOL_01240	4.22e-54	-	-	-	-	-	-	-	-
HKEFDBOL_01241	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HKEFDBOL_01245	1.39e-15	-	-	-	-	-	-	-	-
HKEFDBOL_01247	4.53e-74	-	-	-	L	-	-	-	ribosomal rna small subunit methyltransferase
HKEFDBOL_01248	1.35e-71	-	-	-	-	-	-	-	-
HKEFDBOL_01251	3.62e-68	-	-	-	Q	-	-	-	methyltransferase
HKEFDBOL_01252	8.26e-128	-	-	-	L	-	-	-	Integrase
HKEFDBOL_01255	4.95e-314	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HKEFDBOL_01257	4.78e-261	-	-	-	S	-	-	-	Domain of unknown function (DUF389)
HKEFDBOL_01258	1.9e-13	-	-	-	K	-	-	-	FCD
HKEFDBOL_01259	1.45e-34	-	-	-	K	-	-	-	FCD
HKEFDBOL_01260	6.55e-76	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HKEFDBOL_01261	5.93e-50	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HKEFDBOL_01262	2.39e-222	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
HKEFDBOL_01263	1.17e-102	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HKEFDBOL_01264	6.47e-86	-	-	-	M	-	-	-	Capsular polysaccharide synthesis protein
HKEFDBOL_01265	0.0	-	-	-	S	-	-	-	Fibronectin type III domain
HKEFDBOL_01266	7.03e-307	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HKEFDBOL_01267	9.39e-71	-	-	-	-	-	-	-	-
HKEFDBOL_01269	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HKEFDBOL_01270	1.77e-157	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HKEFDBOL_01271	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKEFDBOL_01272	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKEFDBOL_01273	1.08e-265	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKEFDBOL_01274	1.34e-191	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKEFDBOL_01275	6.71e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKEFDBOL_01276	6.08e-253	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKEFDBOL_01277	6.54e-222	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKEFDBOL_01278	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HKEFDBOL_01279	8.35e-94	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HKEFDBOL_01280	2.02e-38	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKEFDBOL_01282	1.08e-92	-	-	-	-	-	-	-	-
HKEFDBOL_01285	3.34e-139	-	-	-	S	-	-	-	Baseplate J-like protein
HKEFDBOL_01286	6.21e-38	-	-	-	-	-	-	-	-
HKEFDBOL_01287	5.47e-47	-	-	-	-	-	-	-	-
HKEFDBOL_01288	3.05e-126	-	-	-	-	-	-	-	-
HKEFDBOL_01289	9.82e-61	-	-	-	-	-	-	-	-
HKEFDBOL_01290	1.94e-08	lyc2	3.2.1.17	-	M	ko:K01185,ko:K07273	-	ko00000,ko01000	family 25
HKEFDBOL_01291	2.24e-238	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
HKEFDBOL_01294	8.17e-168	-	-	-	S	-	-	-	Protein of unknown function (DUF3383)
HKEFDBOL_01297	5.56e-22	-	-	-	-	-	-	-	-
HKEFDBOL_01298	4.47e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF4054)
HKEFDBOL_01300	8.98e-25	-	-	-	-	-	-	-	-
HKEFDBOL_01301	1.35e-73	-	-	-	S	ko:K09960	-	ko00000	Uncharacterized protein conserved in bacteria (DUF2213)
HKEFDBOL_01302	9.61e-28	-	-	-	S	-	-	-	Lysin motif
HKEFDBOL_01303	9.45e-70	-	-	-	S	-	-	-	Phage Mu protein F like protein
HKEFDBOL_01304	2.06e-111	-	-	-	S	ko:K09961	-	ko00000	Protein of unknown function (DUF1073)
HKEFDBOL_01305	2.12e-234	-	-	-	S	-	-	-	Terminase-like family
HKEFDBOL_01308	9.77e-27	-	-	-	S	-	-	-	N-methyltransferase activity
HKEFDBOL_01316	3.69e-15	-	-	-	S	-	-	-	VRR_NUC
HKEFDBOL_01318	7.58e-90	-	-	-	S	-	-	-	ORF6C domain
HKEFDBOL_01323	9.64e-54	-	-	-	Q	-	-	-	methyltransferase
HKEFDBOL_01328	5.95e-24	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
HKEFDBOL_01329	2.43e-136	-	-	-	L	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
HKEFDBOL_01331	1.36e-13	xre	-	-	K	-	-	-	sequence-specific DNA binding
HKEFDBOL_01333	2.25e-55	-	-	-	S	-	-	-	ERF superfamily
HKEFDBOL_01334	9.01e-65	-	-	-	S	-	-	-	Protein of unknown function (DUF1351)
HKEFDBOL_01338	9.56e-08	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKEFDBOL_01341	2.78e-32	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
HKEFDBOL_01343	3.05e-19	-	-	-	K	-	-	-	Helix-turn-helix domain
HKEFDBOL_01346	2.63e-194	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKEFDBOL_01354	4.65e-219	-	-	-	L	-	-	-	Bifunctional protein
HKEFDBOL_01355	1.67e-143	-	-	-	-	-	-	-	-
HKEFDBOL_01357	1.66e-143	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
HKEFDBOL_01358	4.07e-245	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HKEFDBOL_01359	4.29e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
HKEFDBOL_01360	4.57e-135	-	-	-	S	ko:K06872	-	ko00000	TPM domain
HKEFDBOL_01361	7.26e-172	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
HKEFDBOL_01362	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
HKEFDBOL_01363	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HKEFDBOL_01364	2.72e-189	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HKEFDBOL_01365	5.17e-129	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HKEFDBOL_01366	2.56e-193	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HKEFDBOL_01367	9.99e-53	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HKEFDBOL_01368	2.91e-190	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HKEFDBOL_01369	3.12e-308	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HKEFDBOL_01370	5.52e-113	-	-	-	-	-	-	-	-
HKEFDBOL_01371	0.0	-	-	-	S	-	-	-	SLAP domain
HKEFDBOL_01372	5.4e-226	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKEFDBOL_01373	2.04e-123	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HKEFDBOL_01374	3.46e-80	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HKEFDBOL_01375	8.76e-83	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
HKEFDBOL_01378	1.64e-19	-	-	-	-	-	-	-	-
HKEFDBOL_01380	3.86e-87	-	-	-	S	-	-	-	AAA domain
HKEFDBOL_01381	8.93e-33	-	-	-	S	-	-	-	HNH endonuclease
HKEFDBOL_01387	7.09e-36	-	-	-	-	-	-	-	-
HKEFDBOL_01388	1.12e-159	-	-	-	K	-	-	-	ORF6N domain
HKEFDBOL_01389	1.24e-22	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKEFDBOL_01390	1.7e-23	-	-	-	-	-	-	-	-
HKEFDBOL_01393	1.3e-214	-	-	-	GK	-	-	-	ROK family
HKEFDBOL_01394	9.91e-56	-	-	-	-	-	-	-	-
HKEFDBOL_01395	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HKEFDBOL_01396	1.75e-89	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HKEFDBOL_01397	2.38e-88	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HKEFDBOL_01398	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HKEFDBOL_01399	1.89e-312	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKEFDBOL_01400	7.28e-97	-	-	-	K	-	-	-	acetyltransferase
HKEFDBOL_01401	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKEFDBOL_01402	2.73e-201	msmR	-	-	K	-	-	-	AraC-like ligand binding domain
HKEFDBOL_01403	1.08e-289	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HKEFDBOL_01404	7.92e-135	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HKEFDBOL_01405	1.1e-54	-	-	-	K	-	-	-	Helix-turn-helix
HKEFDBOL_01406	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HKEFDBOL_01408	1.89e-129	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HKEFDBOL_01409	6.79e-270	-	-	-	M	-	-	-	Rib/alpha-like repeat
HKEFDBOL_01410	1.27e-311	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HKEFDBOL_01411	1.64e-59	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HKEFDBOL_01412	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HKEFDBOL_01413	6.98e-78	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HKEFDBOL_01414	1.39e-224	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HKEFDBOL_01415	6.22e-232	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HKEFDBOL_01416	4.43e-179	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HKEFDBOL_01417	7.11e-173	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKEFDBOL_01419	4.14e-113	-	-	-	K	ko:K03484	-	ko00000,ko03000	Periplasmic binding protein domain
HKEFDBOL_01420	0.0	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
HKEFDBOL_01421	2.55e-65	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HKEFDBOL_01422	3.5e-185	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HKEFDBOL_01429	8.25e-65	-	-	-	V	ko:K01990,ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HKEFDBOL_01431	6.56e-86	sagB	-	-	C	-	-	-	Nitroreductase family
HKEFDBOL_01433	1.28e-162	sagD	-	-	S	-	-	-	YcaO cyclodehydratase, ATP-ad Mg2+-binding
HKEFDBOL_01435	1.38e-162	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKEFDBOL_01437	1.45e-133	-	-	-	-	-	-	-	-
HKEFDBOL_01438	1.75e-173	-	-	-	M	-	-	-	Rib/alpha-like repeat
HKEFDBOL_01439	5.22e-05	-	-	-	-	-	-	-	-
HKEFDBOL_01440	1.11e-95	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HKEFDBOL_01441	3.74e-125	-	-	-	-	-	-	-	-
HKEFDBOL_01442	2.12e-86	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
HKEFDBOL_01443	2.24e-36	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
HKEFDBOL_01446	1.8e-162	-	-	-	S	-	-	-	Phage minor structural protein
HKEFDBOL_01449	2.16e-75	-	-	-	V	-	-	-	Abi-like protein
HKEFDBOL_01450	8.88e-178	-	-	-	P	-	-	-	Voltage gated chloride channel
HKEFDBOL_01451	3.44e-238	-	-	-	C	-	-	-	FMN-dependent dehydrogenase
HKEFDBOL_01452	8.68e-69	-	-	-	-	-	-	-	-
HKEFDBOL_01453	1.17e-56	-	-	-	-	-	-	-	-
HKEFDBOL_01454	1.33e-295	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HKEFDBOL_01455	0.0	-	-	-	E	-	-	-	amino acid
HKEFDBOL_01456	1.64e-200	yhaX	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKEFDBOL_01457	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
HKEFDBOL_01458	1.07e-52	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HKEFDBOL_01459	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HKEFDBOL_01460	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HKEFDBOL_01461	9.39e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HKEFDBOL_01462	1.62e-276	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKEFDBOL_01463	8.41e-42	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HKEFDBOL_01464	2.24e-71	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HKEFDBOL_01472	3.15e-93	topB2	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKEFDBOL_01473	6.29e-25	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HKEFDBOL_01474	3.01e-63	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HKEFDBOL_01476	3.09e-42	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HKEFDBOL_01481	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKEFDBOL_01482	8.36e-148	-	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HKEFDBOL_01486	3.5e-280	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKEFDBOL_01487	4.04e-36	-	-	-	-	-	-	-	-
HKEFDBOL_01488	1.33e-72	-	-	-	-	-	-	-	-
HKEFDBOL_01489	1.74e-185	-	-	-	S	-	-	-	Replication initiation factor
HKEFDBOL_01490	1.36e-171	-	-	-	D	-	-	-	Ftsk spoiiie family protein
HKEFDBOL_01491	7.06e-110	-	-	-	-	-	-	-	-
HKEFDBOL_01492	7.2e-84	-	-	-	-	-	-	-	-
HKEFDBOL_01493	6.59e-296	-	-	-	L	-	-	-	Transposase DDE domain
HKEFDBOL_01494	1.23e-166	-	-	-	S	-	-	-	(CBS) domain
HKEFDBOL_01495	2.93e-234	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HKEFDBOL_01496	1.89e-134	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HKEFDBOL_01497	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKEFDBOL_01498	7.32e-46	yabO	-	-	J	-	-	-	S4 domain protein
HKEFDBOL_01499	7.52e-78	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HKEFDBOL_01500	1.61e-81	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
HKEFDBOL_01501	2.75e-307	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HKEFDBOL_01502	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKEFDBOL_01503	3.91e-214	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HKEFDBOL_01504	2.77e-248	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKEFDBOL_01505	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HKEFDBOL_01506	2.84e-108	-	-	-	K	-	-	-	FR47-like protein
HKEFDBOL_01511	4.19e-92	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HKEFDBOL_01515	1.91e-13	-	-	-	S	-	-	-	SLAP domain
HKEFDBOL_01516	1.89e-20	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HKEFDBOL_01518	8.5e-10	-	-	-	M	-	-	-	oxidoreductase activity
HKEFDBOL_01519	3.24e-13	-	-	-	S	-	-	-	SLAP domain
HKEFDBOL_01524	5.28e-165	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
HKEFDBOL_01528	6.51e-194	-	-	-	S	-	-	-	COG0433 Predicted ATPase
HKEFDBOL_01529	2.23e-24	lysM	-	-	M	-	-	-	LysM domain
HKEFDBOL_01532	1.29e-41	-	-	-	O	-	-	-	OsmC-like protein
HKEFDBOL_01534	1.33e-44	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HKEFDBOL_01535	1.8e-20	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKEFDBOL_01537	3.53e-35	-	-	-	C	ko:K21832	-	ko00000	nitric oxide dioxygenase activity
HKEFDBOL_01538	2.28e-78	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
HKEFDBOL_01539	1.94e-217	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
HKEFDBOL_01540	2.36e-217	degV1	-	-	S	-	-	-	DegV family
HKEFDBOL_01541	1.07e-171	-	-	-	V	-	-	-	ABC transporter transmembrane region
HKEFDBOL_01542	5.79e-214	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HKEFDBOL_01543	3.81e-18	-	-	-	S	-	-	-	CsbD-like
HKEFDBOL_01544	2.26e-31	-	-	-	S	-	-	-	Transglycosylase associated protein
HKEFDBOL_01545	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKEFDBOL_01546	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKEFDBOL_01547	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKEFDBOL_01548	7.71e-157	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HKEFDBOL_01549	1.47e-91	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HKEFDBOL_01550	1.39e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HKEFDBOL_01551	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HKEFDBOL_01552	1.63e-180	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
HKEFDBOL_01553	2.62e-95	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKEFDBOL_01554	5.39e-169	-	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	reverse transcriptase
HKEFDBOL_01555	6.34e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HKEFDBOL_01556	3.84e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HKEFDBOL_01557	4.68e-138	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HKEFDBOL_01558	1.14e-63	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HKEFDBOL_01559	3.3e-197	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HKEFDBOL_01560	1.14e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HKEFDBOL_01561	9.07e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HKEFDBOL_01562	8.7e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HKEFDBOL_01563	1.66e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HKEFDBOL_01564	1.45e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HKEFDBOL_01565	1.56e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HKEFDBOL_01566	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HKEFDBOL_01567	3.03e-44	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HKEFDBOL_01568	1.23e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HKEFDBOL_01569	1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKEFDBOL_01570	7.94e-90	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HKEFDBOL_01571	7.18e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HKEFDBOL_01572	4.84e-73	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HKEFDBOL_01573	3.73e-110	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HKEFDBOL_01574	2.22e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HKEFDBOL_01575	2.86e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HKEFDBOL_01576	3.59e-301	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HKEFDBOL_01577	3.7e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HKEFDBOL_01578	3.13e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HKEFDBOL_01579	1.89e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HKEFDBOL_01580	2.07e-73	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HKEFDBOL_01581	3.82e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HKEFDBOL_01582	3.62e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKEFDBOL_01583	2.23e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HKEFDBOL_01584	5.91e-198	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKEFDBOL_01585	1.58e-201	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKEFDBOL_01586	1.53e-175	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKEFDBOL_01587	5.69e-190	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HKEFDBOL_01588	3.22e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HKEFDBOL_01589	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HKEFDBOL_01590	1.44e-234	-	-	-	L	-	-	-	Phage integrase family
HKEFDBOL_01592	2.09e-105	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HKEFDBOL_01594	2.59e-32	-	-	-	S	-	-	-	Hypothetical protein (DUF2513)
HKEFDBOL_01595	5.03e-123	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
HKEFDBOL_01596	4.57e-135	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HKEFDBOL_01597	1.56e-152	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HKEFDBOL_01598	2.02e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HKEFDBOL_01599	3.16e-160	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
HKEFDBOL_01600	8.43e-206	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HKEFDBOL_01601	2.42e-33	-	-	-	-	-	-	-	-
HKEFDBOL_01602	9.82e-164	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKEFDBOL_01603	2.32e-234	-	-	-	S	-	-	-	AAA domain
HKEFDBOL_01604	8.69e-66	-	-	-	-	-	-	-	-
HKEFDBOL_01605	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HKEFDBOL_01606	1.11e-69	-	-	-	-	-	-	-	-
HKEFDBOL_01607	5.22e-131	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HKEFDBOL_01608	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HKEFDBOL_01609	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HKEFDBOL_01610	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HKEFDBOL_01611	2.45e-98	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HKEFDBOL_01612	2.69e-178	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKEFDBOL_01613	1.55e-122	comX	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
HKEFDBOL_01614	1.19e-45	-	-	-	-	-	-	-	-
HKEFDBOL_01615	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HKEFDBOL_01616	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HKEFDBOL_01617	3.73e-33	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HKEFDBOL_01618	5e-130	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HKEFDBOL_01619	2.69e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HKEFDBOL_01620	1.05e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HKEFDBOL_01621	5.48e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HKEFDBOL_01622	1.13e-210	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HKEFDBOL_01623	2.48e-196	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HKEFDBOL_01624	5.24e-187	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKEFDBOL_01625	3.83e-178	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKEFDBOL_01626	2.89e-151	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HKEFDBOL_01627	5.61e-118	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
HKEFDBOL_01629	3.72e-111	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HKEFDBOL_01630	1.61e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HKEFDBOL_01631	9.32e-189	-	2.1.1.172	-	J	ko:K00564,ko:K10716	-	ko00000,ko01000,ko02000,ko03009	Ion channel
HKEFDBOL_01632	5.31e-149	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HKEFDBOL_01633	6.15e-36	-	-	-	-	-	-	-	-
HKEFDBOL_01634	1.08e-117	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HKEFDBOL_01635	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKEFDBOL_01636	1.12e-136	-	-	-	M	-	-	-	family 8
HKEFDBOL_01637	1.15e-47	-	-	-	M	-	-	-	lipopolysaccharide 3-alpha-galactosyltransferase activity
HKEFDBOL_01638	6.31e-68	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HKEFDBOL_01639	9.21e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HKEFDBOL_01640	1.18e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HKEFDBOL_01641	1.15e-146	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HKEFDBOL_01642	1.58e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HKEFDBOL_01643	8.4e-199	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HKEFDBOL_01644	1.4e-80	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HKEFDBOL_01645	3.05e-200	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HKEFDBOL_01646	4.27e-167	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HKEFDBOL_01647	8.72e-111	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HKEFDBOL_01648	3.69e-171	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HKEFDBOL_01649	3.93e-125	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HKEFDBOL_01650	5.79e-247	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HKEFDBOL_01651	1.28e-311	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HKEFDBOL_01652	5.51e-46	-	-	-	S	-	-	-	Transposase C of IS166 homeodomain
HKEFDBOL_01653	4.01e-84	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
HKEFDBOL_01654	9.48e-31	-	-	-	-	-	-	-	-
HKEFDBOL_01655	3.06e-53	bbsF_1	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HKEFDBOL_01656	6.43e-230	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HKEFDBOL_01657	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HKEFDBOL_01658	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HKEFDBOL_01659	8.74e-146	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HKEFDBOL_01660	2.3e-36	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HKEFDBOL_01662	4.74e-110	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKEFDBOL_01663	1.21e-243	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
HKEFDBOL_01665	3.99e-56	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
HKEFDBOL_01666	2.14e-234	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HKEFDBOL_01667	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HKEFDBOL_01668	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKEFDBOL_01669	2.14e-231	-	-	-	M	-	-	-	CHAP domain
HKEFDBOL_01670	2.79e-102	-	-	-	-	-	-	-	-
HKEFDBOL_01671	1.06e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HKEFDBOL_01672	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HKEFDBOL_01673	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HKEFDBOL_01674	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HKEFDBOL_01675	3.89e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HKEFDBOL_01676	1.39e-237	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HKEFDBOL_01677	7.58e-69	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HKEFDBOL_01681	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HKEFDBOL_01682	6.15e-268	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKEFDBOL_01683	3.16e-231	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HKEFDBOL_01684	1.26e-303	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HKEFDBOL_01685	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HKEFDBOL_01686	5.32e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HKEFDBOL_01687	9.37e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HKEFDBOL_01688	1.18e-66	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HKEFDBOL_01689	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HKEFDBOL_01690	5.37e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HKEFDBOL_01691	2.34e-76	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HKEFDBOL_01692	5.62e-95	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HKEFDBOL_01693	4.13e-186	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HKEFDBOL_01694	8.12e-144	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HKEFDBOL_01695	1.55e-29	-	-	-	-	-	-	-	-
HKEFDBOL_01696	5.53e-147	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HKEFDBOL_01697	4.31e-175	-	-	-	-	-	-	-	-
HKEFDBOL_01698	4.52e-126	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKEFDBOL_01699	4.28e-187	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HKEFDBOL_01700	2.96e-23	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HKEFDBOL_01701	3.09e-71	-	-	-	-	-	-	-	-
HKEFDBOL_01702	1.6e-272	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HKEFDBOL_01703	1.23e-231	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HKEFDBOL_01704	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HKEFDBOL_01705	9.89e-74	-	-	-	-	-	-	-	-
HKEFDBOL_01706	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HKEFDBOL_01707	4.25e-119	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HKEFDBOL_01708	6.38e-184	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HKEFDBOL_01709	2.15e-137	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HKEFDBOL_01710	2.76e-49	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HKEFDBOL_01711	1.1e-145	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HKEFDBOL_01712	1.76e-234	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HKEFDBOL_01713	2.5e-136	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
HKEFDBOL_01731	2.53e-89	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKEFDBOL_01734	1.12e-21	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKEFDBOL_01736	2.99e-142	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
HKEFDBOL_01740	8.59e-107	-	-	-	S	-	-	-	Protein of unknown function (DUF1351)
HKEFDBOL_01741	1.27e-93	-	-	-	S	-	-	-	ERF superfamily
HKEFDBOL_01742	3.04e-85	-	-	-	L	-	-	-	DnaD domain protein
HKEFDBOL_01750	1.06e-30	-	-	-	N	-	-	-	PFAM Uncharacterised protein family UPF0150
HKEFDBOL_01751	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HKEFDBOL_01752	5.32e-285	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
HKEFDBOL_01753	4.38e-150	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
HKEFDBOL_01757	1.8e-49	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
HKEFDBOL_01758	7.31e-130	-	-	-	M	-	-	-	hydrolase, family 25
HKEFDBOL_01761	5.1e-09	-	-	-	-	-	-	-	-
HKEFDBOL_01774	1.72e-286	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
HKEFDBOL_01775	3.68e-256	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HKEFDBOL_01776	5.35e-224	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKEFDBOL_01777	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HKEFDBOL_01778	1.3e-40	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HKEFDBOL_01779	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HKEFDBOL_01780	1.58e-101	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HKEFDBOL_01782	1.58e-09	-	-	-	S	-	-	-	Phage uncharacterised protein (Phage_XkdX)
HKEFDBOL_01785	1.28e-22	-	-	-	-	-	-	-	-
HKEFDBOL_01786	1.66e-36	-	-	-	-	-	-	-	-
HKEFDBOL_01787	2.14e-103	-	-	-	-	-	-	-	-
HKEFDBOL_01789	2.72e-236	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HKEFDBOL_01790	9.65e-181	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HKEFDBOL_01791	3.51e-222	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HKEFDBOL_01792	1.31e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
HKEFDBOL_01793	2.07e-203	-	-	-	K	-	-	-	Transcriptional regulator
HKEFDBOL_01794	7.06e-111	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HKEFDBOL_01795	3.25e-308	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HKEFDBOL_01796	4.47e-58	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HKEFDBOL_01797	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HKEFDBOL_01798	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HKEFDBOL_01799	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
HKEFDBOL_01800	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKEFDBOL_01801	4.33e-40	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKEFDBOL_01802	5.75e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKEFDBOL_01803	2.7e-277	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HKEFDBOL_01804	5.26e-36	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HKEFDBOL_01805	1.78e-100	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HKEFDBOL_01806	3.36e-42	-	-	-	-	-	-	-	-
HKEFDBOL_01807	9.05e-78	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
HKEFDBOL_01808	6.94e-202	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKEFDBOL_01809	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
HKEFDBOL_01810	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HKEFDBOL_01811	1.23e-242	-	-	-	S	-	-	-	TerB-C domain
HKEFDBOL_01812	1.85e-141	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HKEFDBOL_01813	7.86e-138	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
HKEFDBOL_01815	5.53e-173	-	-	-	S	-	-	-	TerB-C domain
HKEFDBOL_01816	2.14e-312	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
HKEFDBOL_01817	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
HKEFDBOL_01818	7.82e-80	-	-	-	-	-	-	-	-
HKEFDBOL_01819	1.49e-290	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HKEFDBOL_01820	7.25e-59	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HKEFDBOL_01821	2.9e-82	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HKEFDBOL_01823	3.31e-79	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
HKEFDBOL_01824	1.08e-145	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HKEFDBOL_01825	3.65e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HKEFDBOL_01827	1.04e-41	-	-	-	-	-	-	-	-
HKEFDBOL_01828	1.32e-218	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
HKEFDBOL_01829	1.25e-17	-	-	-	-	-	-	-	-
HKEFDBOL_01830	1.83e-22	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKEFDBOL_01831	6.31e-99	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKEFDBOL_01832	2.57e-108	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKEFDBOL_01833	1.33e-130	-	-	-	M	-	-	-	LysM domain protein
HKEFDBOL_01834	5.68e-211	-	-	-	D	-	-	-	nuclear chromosome segregation
HKEFDBOL_01835	8.92e-136	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HKEFDBOL_01836	9.01e-115	-	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
HKEFDBOL_01837	1.9e-153	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
HKEFDBOL_01838	2.67e-148	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HKEFDBOL_01840	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
HKEFDBOL_01842	1.93e-266	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HKEFDBOL_01843	1.06e-139	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HKEFDBOL_01844	1.19e-83	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HKEFDBOL_01845	3.01e-154	rpiA1	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HKEFDBOL_01846	1.43e-186	-	-	-	K	-	-	-	SIS domain
HKEFDBOL_01847	1.76e-65	slpX	-	-	S	-	-	-	SLAP domain
HKEFDBOL_01848	3.98e-210	slpX	-	-	S	-	-	-	SLAP domain
HKEFDBOL_01849	6.39e-32	-	-	-	S	-	-	-	transposase or invertase
HKEFDBOL_01850	1.18e-13	-	-	-	-	-	-	-	-
HKEFDBOL_01851	4.41e-305	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HKEFDBOL_01854	7.83e-303	oppA2	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKEFDBOL_01855	1.15e-54	oppA2	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKEFDBOL_01856	2.17e-232	-	-	-	-	-	-	-	-
HKEFDBOL_01857	9.75e-163	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
HKEFDBOL_01858	3.68e-93	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HKEFDBOL_01859	3.02e-171	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HKEFDBOL_01860	1.03e-261	-	-	-	M	-	-	-	Glycosyl transferases group 1
HKEFDBOL_01861	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKEFDBOL_01862	1.91e-195	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HKEFDBOL_01863	9.83e-261	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
HKEFDBOL_01864	3.53e-309	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HKEFDBOL_01865	6.86e-281	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HKEFDBOL_01866	9.16e-287	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKEFDBOL_01867	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HKEFDBOL_01868	5.48e-173	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
HKEFDBOL_01869	2.62e-109	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HKEFDBOL_01871	2.26e-118	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HKEFDBOL_01872	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HKEFDBOL_01873	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKEFDBOL_01874	6.25e-268	camS	-	-	S	-	-	-	sex pheromone
HKEFDBOL_01875	5.42e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKEFDBOL_01876	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HKEFDBOL_01877	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKEFDBOL_01878	5.58e-219	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HKEFDBOL_01879	2.61e-148	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HKEFDBOL_01880	1.46e-75	-	-	-	-	-	-	-	-
HKEFDBOL_01881	9.92e-187	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HKEFDBOL_01882	2.79e-309	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HKEFDBOL_01883	1.01e-256	flp	-	-	V	-	-	-	Beta-lactamase
HKEFDBOL_01884	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKEFDBOL_01885	1.66e-121	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKEFDBOL_01890	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HKEFDBOL_01891	1.52e-119	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKEFDBOL_01892	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HKEFDBOL_01893	6.61e-186	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
HKEFDBOL_01894	1.6e-161	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKEFDBOL_01895	6.13e-110	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKEFDBOL_01896	5.94e-200	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HKEFDBOL_01897	8.97e-47	-	-	-	-	-	-	-	-
HKEFDBOL_01899	3.51e-96	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative DNA-binding domain
HKEFDBOL_01900	4.63e-32	-	-	-	-	-	-	-	-
HKEFDBOL_01901	6.72e-177	-	-	-	EP	-	-	-	Plasmid replication protein
HKEFDBOL_01902	6.79e-102	-	-	-	S	-	-	-	helix_turn_helix, Deoxyribose operon repressor
HKEFDBOL_01903	3.05e-110	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HKEFDBOL_01904	3.68e-176	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HKEFDBOL_01906	3.55e-28	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative DNA-binding domain
HKEFDBOL_01907	3.34e-303	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HKEFDBOL_01908	1.02e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HKEFDBOL_01909	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HKEFDBOL_01910	1.06e-195	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
HKEFDBOL_01911	2.33e-230	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
HKEFDBOL_01912	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HKEFDBOL_01913	6.07e-223	ydhF	-	-	S	-	-	-	Aldo keto reductase
HKEFDBOL_01914	1.53e-176	-	-	-	-	-	-	-	-
HKEFDBOL_01915	1.11e-256	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HKEFDBOL_01916	3.97e-33	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HKEFDBOL_01917	4.41e-307	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HKEFDBOL_01918	1.07e-165	-	-	-	F	-	-	-	glutamine amidotransferase
HKEFDBOL_01919	2.05e-188	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKEFDBOL_01920	2.53e-106	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HKEFDBOL_01921	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HKEFDBOL_01922	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
HKEFDBOL_01923	1.72e-129	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HKEFDBOL_01924	8.41e-314	-	-	-	G	-	-	-	MFS/sugar transport protein
HKEFDBOL_01925	5.43e-50	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
HKEFDBOL_01926	2.72e-60	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
HKEFDBOL_01927	2.8e-173	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKEFDBOL_01928	3.39e-187	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HKEFDBOL_01929	4.29e-122	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKEFDBOL_01930	3.65e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKEFDBOL_01931	1.04e-211	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
HKEFDBOL_01932	2.09e-110	-	-	-	-	-	-	-	-
HKEFDBOL_01933	1.25e-94	-	-	-	K	-	-	-	Helix-turn-helix domain
HKEFDBOL_01935	6.66e-27	-	-	-	S	-	-	-	CAAX protease self-immunity
HKEFDBOL_01936	2.67e-35	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HKEFDBOL_01938	4.11e-124	potE	-	-	E	-	-	-	thought to be involved in transport amino acids across the membrane
HKEFDBOL_01940	3.17e-189	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HKEFDBOL_01942	5.61e-38	-	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HKEFDBOL_01943	0.0	-	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HKEFDBOL_01944	1.09e-148	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HKEFDBOL_01945	3.26e-292	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HKEFDBOL_01946	3e-118	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HKEFDBOL_01947	1.38e-162	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKEFDBOL_01948	2.82e-17	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HKEFDBOL_01949	2.73e-21	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HKEFDBOL_01950	6.8e-48	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
HKEFDBOL_01951	3.48e-105	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
HKEFDBOL_01952	5.44e-299	-	-	-	V	-	-	-	N-6 DNA Methylase
HKEFDBOL_01953	1.11e-131	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
HKEFDBOL_01954	1.71e-156	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HKEFDBOL_01955	7.98e-35	-	-	-	GKT	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKEFDBOL_01956	4.68e-25	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKEFDBOL_01957	8.24e-257	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HKEFDBOL_01958	7.62e-32	-	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKEFDBOL_01960	1.78e-21	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
HKEFDBOL_01961	5.85e-67	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
HKEFDBOL_01963	1.54e-87	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
HKEFDBOL_01964	2.78e-45	-	-	-	-	-	-	-	-
HKEFDBOL_01966	7.63e-28	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKEFDBOL_01968	2.62e-155	-	-	-	L	-	-	-	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HKEFDBOL_01970	7.33e-19	-	-	-	-	-	-	-	-
HKEFDBOL_01971	1.02e-32	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
HKEFDBOL_01972	7.21e-54	-	-	-	E	-	-	-	Pfam:DUF955
HKEFDBOL_01973	3.71e-142	-	-	-	S	-	-	-	Fic/DOC family
HKEFDBOL_01974	4.2e-22	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HKEFDBOL_01975	2.64e-34	-	-	-	L	-	-	-	four-way junction helicase activity
HKEFDBOL_01979	4.26e-22	-	-	-	L	ko:K07467	-	ko00000	Replication initiation factor
HKEFDBOL_01980	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKEFDBOL_01981	5.23e-97	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
HKEFDBOL_01982	1.48e-249	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKEFDBOL_01983	1.07e-141	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
HKEFDBOL_01984	6.91e-92	-	-	-	L	-	-	-	IS1381, transposase OrfA
HKEFDBOL_01985	4.87e-96	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HKEFDBOL_01986	1.17e-38	-	-	-	-	-	-	-	-
HKEFDBOL_01987	4.65e-184	-	-	-	D	-	-	-	AAA domain
HKEFDBOL_01988	5.88e-212	repA	-	-	S	-	-	-	Replication initiator protein A
HKEFDBOL_01989	1.14e-164	-	-	-	S	-	-	-	Fic/DOC family
HKEFDBOL_01990	1.79e-74	-	-	-	L	-	-	-	Resolvase, N-terminal
HKEFDBOL_01991	4.18e-208	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
HKEFDBOL_01992	1.86e-243	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HKEFDBOL_01998	6.33e-221	ulaG	-	-	S	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Beta-lactamase superfamily domain
HKEFDBOL_01999	4.93e-80	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKEFDBOL_02000	6.58e-293	sgaT	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HKEFDBOL_02001	4.82e-42	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKEFDBOL_02002	2.85e-115	ulaD	4.1.1.85, 4.1.2.43	-	G	ko:K03078,ko:K08093	ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
HKEFDBOL_02003	1.78e-163	sga	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
HKEFDBOL_02004	1.52e-157	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HKEFDBOL_02005	5.85e-86	nt5e	3.1.3.18	-	L	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
HKEFDBOL_02006	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HKEFDBOL_02007	1.01e-22	-	-	-	L	-	-	-	Transposase
HKEFDBOL_02008	7.51e-16	-	-	-	L	-	-	-	Transposase
HKEFDBOL_02009	3.76e-18	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKEFDBOL_02010	3.52e-296	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HKEFDBOL_02011	2.2e-308	srrA1	-	-	G	ko:K02027,ko:K17244	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKEFDBOL_02012	7.29e-209	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HKEFDBOL_02013	8.52e-215	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKEFDBOL_02014	1.82e-161	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HKEFDBOL_02015	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HKEFDBOL_02016	1.01e-222	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HKEFDBOL_02017	6.63e-174	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HKEFDBOL_02018	3.18e-198	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HKEFDBOL_02019	2.9e-79	-	-	-	S	-	-	-	Enterocin A Immunity
HKEFDBOL_02020	4.44e-174	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HKEFDBOL_02021	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HKEFDBOL_02022	1.85e-205	-	-	-	S	-	-	-	Phospholipase, patatin family
HKEFDBOL_02023	7.44e-189	-	-	-	S	-	-	-	hydrolase
HKEFDBOL_02024	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HKEFDBOL_02025	6.89e-190	glvR	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
HKEFDBOL_02026	1.52e-103	-	-	-	-	-	-	-	-
HKEFDBOL_02027	1.96e-113	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HKEFDBOL_02028	1.76e-52	-	-	-	-	-	-	-	-
HKEFDBOL_02029	2.14e-154	-	-	-	C	-	-	-	nitroreductase
HKEFDBOL_02030	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HKEFDBOL_02031	8.59e-133	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HKEFDBOL_02032	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HKEFDBOL_02033	7.06e-114	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HKEFDBOL_02034	5.83e-67	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HKEFDBOL_02035	6.74e-269	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HKEFDBOL_02036	7.32e-157	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HKEFDBOL_02037	2.22e-296	-	-	-	E	ko:K03294	-	ko00000	amino acid
HKEFDBOL_02038	1.28e-33	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKEFDBOL_02039	6.73e-78	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HKEFDBOL_02040	2.16e-79	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HKEFDBOL_02041	4.89e-282	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HKEFDBOL_02042	3.76e-316	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKEFDBOL_02044	1.62e-278	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HKEFDBOL_02045	7.46e-113	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
HKEFDBOL_02046	5.14e-105	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HKEFDBOL_02047	9.98e-211	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HKEFDBOL_02048	3.44e-209	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HKEFDBOL_02049	3.22e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HKEFDBOL_02050	1.22e-272	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HKEFDBOL_02051	4.42e-269	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HKEFDBOL_02052	7.74e-61	-	-	-	-	-	-	-	-
HKEFDBOL_02053	1.04e-48	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HKEFDBOL_02054	1.94e-150	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HKEFDBOL_02055	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKEFDBOL_02056	2.79e-185	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HKEFDBOL_02057	1.74e-111	-	-	-	-	-	-	-	-
HKEFDBOL_02058	7.76e-98	-	-	-	-	-	-	-	-
HKEFDBOL_02059	1.76e-181	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
HKEFDBOL_02060	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HKEFDBOL_02061	5.93e-60	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
HKEFDBOL_02062	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HKEFDBOL_02063	3.3e-203	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HKEFDBOL_02064	7.13e-67	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
HKEFDBOL_02065	1.53e-189	-	5.2.1.13	-	Q	ko:K09835	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko00002,ko01000	HI0933-like protein
HKEFDBOL_02066	3.43e-79	-	-	-	C	-	-	-	2Fe-2S iron-sulfur cluster binding domain
HKEFDBOL_02067	1.28e-168	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
HKEFDBOL_02068	2.6e-37	-	-	-	-	-	-	-	-
HKEFDBOL_02069	1.29e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HKEFDBOL_02070	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKEFDBOL_02071	6.28e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HKEFDBOL_02072	8.7e-178	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HKEFDBOL_02073	2.63e-205	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HKEFDBOL_02074	5.74e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
HKEFDBOL_02075	2.44e-143	-	-	-	S	-	-	-	CYTH
HKEFDBOL_02076	1.7e-147	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HKEFDBOL_02077	1.91e-195	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKEFDBOL_02078	7.96e-221	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HKEFDBOL_02079	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HKEFDBOL_02080	3.77e-122	-	-	-	S	-	-	-	SNARE associated Golgi protein
HKEFDBOL_02081	1.01e-255	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HKEFDBOL_02082	1.99e-87	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HKEFDBOL_02083	2.19e-270	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
HKEFDBOL_02084	2.12e-136	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HKEFDBOL_02085	3.12e-91	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
HKEFDBOL_02086	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HKEFDBOL_02087	1.47e-284	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HKEFDBOL_02088	5.49e-301	ymfH	-	-	S	-	-	-	Peptidase M16
HKEFDBOL_02089	1.39e-171	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HKEFDBOL_02090	2.31e-154	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HKEFDBOL_02091	3.92e-123	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKEFDBOL_02092	1.17e-248	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HKEFDBOL_02093	3.03e-293	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HKEFDBOL_02094	1.94e-268	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
HKEFDBOL_02095	5.04e-154	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HKEFDBOL_02096	2.68e-314	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HKEFDBOL_02097	9.44e-169	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HKEFDBOL_02098	1.55e-122	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HKEFDBOL_02099	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKEFDBOL_02100	2.24e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HKEFDBOL_02101	8.33e-27	-	-	-	-	-	-	-	-
HKEFDBOL_02102	3.54e-230	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HKEFDBOL_02103	4.04e-203	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HKEFDBOL_02104	3.31e-239	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HKEFDBOL_02105	3.42e-232	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HKEFDBOL_02106	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HKEFDBOL_02107	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HKEFDBOL_02108	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HKEFDBOL_02109	1.55e-117	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HKEFDBOL_02110	2.44e-211	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HKEFDBOL_02111	2.78e-251	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HKEFDBOL_02112	8.59e-221	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HKEFDBOL_02113	1.16e-128	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HKEFDBOL_02114	0.0	-	-	-	S	-	-	-	SH3-like domain
HKEFDBOL_02115	3.16e-144	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKEFDBOL_02116	4.76e-168	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HKEFDBOL_02117	2.54e-225	ydbI	-	-	K	-	-	-	AI-2E family transporter
HKEFDBOL_02118	1.95e-134	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HKEFDBOL_02119	2.55e-26	-	-	-	-	-	-	-	-
HKEFDBOL_02120	1.06e-311	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HKEFDBOL_02121	2.81e-102	-	-	-	E	-	-	-	Zn peptidase
HKEFDBOL_02122	7.12e-55	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKEFDBOL_02123	7.61e-59	-	-	-	-	-	-	-	-
HKEFDBOL_02124	1.08e-79	-	-	-	S	-	-	-	Bacteriocin helveticin-J
HKEFDBOL_02125	3.56e-85	-	-	-	S	-	-	-	SLAP domain
HKEFDBOL_02126	8.58e-60	-	-	-	-	-	-	-	-
HKEFDBOL_02127	8.64e-176	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKEFDBOL_02128	4.76e-168	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HKEFDBOL_02129	3.35e-223	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HKEFDBOL_02130	7.75e-170	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HKEFDBOL_02131	7.93e-63	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HKEFDBOL_02132	5.49e-97	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HKEFDBOL_02133	9.52e-205	yvgN	-	-	C	-	-	-	Aldo keto reductase
HKEFDBOL_02134	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HKEFDBOL_02135	3.16e-192	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	haloacid dehalogenase-like hydrolase
HKEFDBOL_02136	3.74e-180	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKEFDBOL_02138	4.64e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HKEFDBOL_02139	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HKEFDBOL_02140	7.65e-101	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HKEFDBOL_02141	1.43e-178	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HKEFDBOL_02142	0.0	ycaM	-	-	E	-	-	-	amino acid
HKEFDBOL_02143	0.0	-	-	-	-	-	-	-	-
HKEFDBOL_02145	9.26e-241	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HKEFDBOL_02146	2.86e-244	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HKEFDBOL_02147	2.86e-286	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HKEFDBOL_02148	5.46e-183	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKEFDBOL_02149	1.18e-253	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
HKEFDBOL_02150	3.07e-124	-	-	-	-	-	-	-	-
HKEFDBOL_02151	1.45e-109	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKEFDBOL_02152	5.95e-66	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKEFDBOL_02153	1.64e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HKEFDBOL_02154	1.1e-232	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HKEFDBOL_02155	4.82e-113	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HKEFDBOL_02156	1.51e-127	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HKEFDBOL_02157	1.64e-207	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HKEFDBOL_02158	1.25e-263	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HKEFDBOL_02159	8.77e-173	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKEFDBOL_02160	3.69e-170	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKEFDBOL_02161	3.46e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKEFDBOL_02162	2.13e-194	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HKEFDBOL_02163	2.76e-221	ybbR	-	-	S	-	-	-	YbbR-like protein
HKEFDBOL_02164	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKEFDBOL_02165	8.04e-190	-	-	-	S	-	-	-	hydrolase
HKEFDBOL_02166	3.23e-98	copY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
HKEFDBOL_02167	2.85e-153	-	-	-	-	-	-	-	-
HKEFDBOL_02168	3.07e-112	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKEFDBOL_02169	2.52e-262	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HKEFDBOL_02170	8.39e-195	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HKEFDBOL_02171	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKEFDBOL_02172	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKEFDBOL_02173	5.12e-199	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HKEFDBOL_02174	1.74e-60	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HKEFDBOL_02175	4.11e-44	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HKEFDBOL_02176	2.21e-34	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
HKEFDBOL_02177	7.67e-135	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
HKEFDBOL_02178	2.64e-46	-	-	-	-	-	-	-	-
HKEFDBOL_02179	1.96e-110	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
HKEFDBOL_02180	1.14e-99	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKEFDBOL_02182	0.0	-	-	-	E	-	-	-	Amino acid permease
HKEFDBOL_02183	2.15e-127	-	-	-	L	-	-	-	Helix-turn-helix domain
HKEFDBOL_02184	4.31e-204	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HKEFDBOL_02186	3.96e-37	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKEFDBOL_02187	1.49e-130	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
HKEFDBOL_02188	2.33e-120	-	-	-	S	-	-	-	VanZ like family
HKEFDBOL_02189	5.65e-171	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HKEFDBOL_02190	5.04e-231	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HKEFDBOL_02191	1.72e-222	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HKEFDBOL_02192	7.88e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HKEFDBOL_02193	8.19e-91	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
HKEFDBOL_02194	1.68e-55	-	-	-	-	-	-	-	-
HKEFDBOL_02195	1.94e-100	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
HKEFDBOL_02196	3.69e-30	-	-	-	-	-	-	-	-
HKEFDBOL_02197	2.42e-238	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HKEFDBOL_02198	1.07e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKEFDBOL_02201	9.18e-188	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKEFDBOL_02203	1.74e-33	-	-	-	K	-	-	-	Helix-turn-helix domain
HKEFDBOL_02204	1.12e-28	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
HKEFDBOL_02205	2.91e-37	-	-	-	K	-	-	-	Helix-turn-helix domain
HKEFDBOL_02207	2.13e-14	-	-	-	S	-	-	-	Arc-like DNA binding domain
HKEFDBOL_02210	3.07e-35	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
HKEFDBOL_02218	6.57e-45	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
HKEFDBOL_02219	1.49e-47	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKEFDBOL_02221	9.34e-231	-	-	-	L	-	-	-	N-6 DNA Methylase
HKEFDBOL_02223	4.48e-10	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HKEFDBOL_02226	1e-22	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3850)
HKEFDBOL_02228	3e-128	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HKEFDBOL_02229	1.72e-288	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HKEFDBOL_02230	1.93e-242	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HKEFDBOL_02231	9.01e-90	-	-	-	S	-	-	-	SdpI/YhfL protein family
HKEFDBOL_02232	1.97e-170	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HKEFDBOL_02233	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HKEFDBOL_02234	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HKEFDBOL_02235	1.52e-136	vanZ	-	-	V	-	-	-	VanZ like family
HKEFDBOL_02236	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HKEFDBOL_02237	4.63e-274	-	-	-	EGP	-	-	-	Major Facilitator
HKEFDBOL_02238	3.94e-250	ampC	-	-	V	-	-	-	Beta-lactamase
HKEFDBOL_02241	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
HKEFDBOL_02242	9.98e-146	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HKEFDBOL_02243	6.6e-237	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HKEFDBOL_02244	1.24e-198	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HKEFDBOL_02245	1.36e-242	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HKEFDBOL_02246	5.28e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HKEFDBOL_02247	1.01e-166	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HKEFDBOL_02248	4.83e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKEFDBOL_02249	2.57e-83	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HKEFDBOL_02250	3.24e-120	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKEFDBOL_02251	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HKEFDBOL_02252	1.04e-221	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HKEFDBOL_02253	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HKEFDBOL_02254	2.45e-93	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HKEFDBOL_02255	2.54e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
HKEFDBOL_02256	4.81e-227	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HKEFDBOL_02257	1.59e-68	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HKEFDBOL_02258	5.13e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HKEFDBOL_02259	1.18e-275	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HKEFDBOL_02260	9.45e-104	uspA	-	-	T	-	-	-	universal stress protein
HKEFDBOL_02261	1.35e-56	-	-	-	-	-	-	-	-
HKEFDBOL_02262	5.98e-302	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HKEFDBOL_02263	8.08e-110	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HKEFDBOL_02264	3.07e-142	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HKEFDBOL_02265	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HKEFDBOL_02266	1.32e-271	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HKEFDBOL_02267	3.48e-288	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HKEFDBOL_02268	2.1e-232	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HKEFDBOL_02269	6.01e-153	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HKEFDBOL_02270	3.97e-57	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HKEFDBOL_02271	1.06e-86	-	-	-	S	-	-	-	GtrA-like protein
HKEFDBOL_02272	4.08e-218	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HKEFDBOL_02273	3.33e-123	-	-	-	S	-	-	-	Protein of unknown function (DUF3990)
HKEFDBOL_02274	8.53e-59	-	-	-	-	-	-	-	-
HKEFDBOL_02275	9.25e-13	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HKEFDBOL_02276	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HKEFDBOL_02277	3.02e-166	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
HKEFDBOL_02278	2.91e-67	-	-	-	-	-	-	-	-
HKEFDBOL_02279	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HKEFDBOL_02280	1.22e-306	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HKEFDBOL_02281	1.06e-162	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HKEFDBOL_02282	6.18e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HKEFDBOL_02283	8.26e-226	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HKEFDBOL_02284	8.27e-189	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HKEFDBOL_02285	5.43e-122	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
HKEFDBOL_02286	1.4e-09	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
HKEFDBOL_02287	1.02e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
HKEFDBOL_02288	5.63e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HKEFDBOL_02289	1.49e-223	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HKEFDBOL_02290	6.55e-72	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HKEFDBOL_02291	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HKEFDBOL_02292	4.43e-224	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HKEFDBOL_02293	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HKEFDBOL_02294	3.88e-264	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HKEFDBOL_02295	3.14e-194	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HKEFDBOL_02296	3.3e-315	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HKEFDBOL_02297	2.52e-300	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HKEFDBOL_02298	1.43e-96	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HKEFDBOL_02299	2.42e-60	yggT	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HKEFDBOL_02300	4.01e-192	ylmH	-	-	S	-	-	-	S4 domain protein
HKEFDBOL_02301	6.3e-138	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HKEFDBOL_02302	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HKEFDBOL_02303	2.32e-43	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HKEFDBOL_02304	5.18e-134	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HKEFDBOL_02305	1.22e-55	-	-	-	-	-	-	-	-
HKEFDBOL_02306	2.05e-163	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HKEFDBOL_02307	1.62e-276	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HKEFDBOL_02308	9.98e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HKEFDBOL_02309	4.47e-278	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HKEFDBOL_02310	4.7e-163	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
HKEFDBOL_02311	2.31e-148	-	-	-	S	-	-	-	repeat protein
HKEFDBOL_02312	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HKEFDBOL_02313	0.0	-	-	-	L	-	-	-	Nuclease-related domain
HKEFDBOL_02314	1.75e-211	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HKEFDBOL_02315	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKEFDBOL_02316	5.22e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HKEFDBOL_02317	2.79e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKEFDBOL_02318	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HKEFDBOL_02319	3.91e-268	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HKEFDBOL_02320	9.94e-71	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HKEFDBOL_02321	5.21e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HKEFDBOL_02322	7.07e-107	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HKEFDBOL_02323	1.42e-244	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HKEFDBOL_02324	2.7e-126	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HKEFDBOL_02325	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HKEFDBOL_02326	2.57e-226	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HKEFDBOL_02327	3.64e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HKEFDBOL_02328	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HKEFDBOL_02329	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKEFDBOL_02330	5.43e-191	-	-	-	-	-	-	-	-
HKEFDBOL_02331	5.76e-287	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKEFDBOL_02332	2.56e-291	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HKEFDBOL_02333	3.04e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HKEFDBOL_02334	1.59e-136	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HKEFDBOL_02335	2.58e-48	potE	-	-	E	-	-	-	Amino Acid
HKEFDBOL_02336	1.27e-220	potE	-	-	E	-	-	-	Amino Acid
HKEFDBOL_02337	6.25e-246	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HKEFDBOL_02338	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HKEFDBOL_02339	1.39e-312	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HKEFDBOL_02340	8.62e-105	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HKEFDBOL_02341	3.29e-280	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HKEFDBOL_02342	3.66e-225	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKEFDBOL_02343	6.89e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HKEFDBOL_02344	9.03e-277	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HKEFDBOL_02345	2.48e-252	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HKEFDBOL_02346	4.2e-249	pbpX1	-	-	V	-	-	-	Beta-lactamase
HKEFDBOL_02347	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
HKEFDBOL_02348	1.83e-54	-	-	-	C	-	-	-	FMN_bind
HKEFDBOL_02349	4.49e-108	-	-	-	-	-	-	-	-
HKEFDBOL_02350	3.14e-226	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
HKEFDBOL_02351	2.06e-111	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
HKEFDBOL_02352	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKEFDBOL_02353	4.65e-166	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA domain
HKEFDBOL_02354	2.19e-73	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKEFDBOL_02355	7.88e-79	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
HKEFDBOL_02356	1.33e-92	-	-	-	-	-	-	-	-
HKEFDBOL_02357	4.06e-88	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKEFDBOL_02358	1.64e-215	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKEFDBOL_02359	2.73e-92	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HKEFDBOL_02360	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKEFDBOL_02361	2.3e-169	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
HKEFDBOL_02362	4.22e-288	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKEFDBOL_02363	4.06e-39	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKEFDBOL_02364	1.31e-56	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKEFDBOL_02365	8.72e-258	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKEFDBOL_02366	2.08e-95	yfhC	-	-	C	-	-	-	nitroreductase
HKEFDBOL_02367	3.87e-16	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HKEFDBOL_02368	6.14e-107	-	-	-	-	-	-	-	-
HKEFDBOL_02369	1.67e-95	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HKEFDBOL_02370	8.44e-65	-	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HKEFDBOL_02371	9.89e-112	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKEFDBOL_02372	1.98e-47	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKEFDBOL_02373	4.22e-41	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKEFDBOL_02374	2.77e-177	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HKEFDBOL_02375	1.4e-137	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HKEFDBOL_02376	2.53e-268	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKEFDBOL_02377	3.17e-67	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HKEFDBOL_02378	7.28e-80	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HKEFDBOL_02379	3.44e-300	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HKEFDBOL_02380	4.9e-180	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HKEFDBOL_02381	2.42e-163	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HKEFDBOL_02382	1.9e-158	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HKEFDBOL_02383	7.01e-103	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HKEFDBOL_02384	2.27e-245	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKEFDBOL_02385	1.44e-07	-	-	-	S	-	-	-	YSIRK type signal peptide
HKEFDBOL_02387	3.45e-202	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HKEFDBOL_02388	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
HKEFDBOL_02389	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HKEFDBOL_02390	6.72e-261	pbpX	-	-	V	-	-	-	Beta-lactamase
HKEFDBOL_02391	1.05e-289	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HKEFDBOL_02392	4.19e-92	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HKEFDBOL_02393	3.73e-72	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HKEFDBOL_02394	1.43e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKEFDBOL_02395	1.23e-187	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HKEFDBOL_02396	1.94e-130	-	-	-	I	-	-	-	PAP2 superfamily
HKEFDBOL_02397	1.21e-243	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HKEFDBOL_02399	1.73e-227	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HKEFDBOL_02400	1.63e-109	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HKEFDBOL_02401	3.87e-15	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN_bind
HKEFDBOL_02402	2.33e-130	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
HKEFDBOL_02403	2.43e-95	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HKEFDBOL_02404	4.36e-93	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HKEFDBOL_02405	8.44e-300	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HKEFDBOL_02406	2.16e-50	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HKEFDBOL_02407	5.66e-16	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HKEFDBOL_02408	1.16e-13	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HKEFDBOL_02409	2.43e-118	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HKEFDBOL_02410	5.47e-103	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HKEFDBOL_02411	2.28e-281	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HKEFDBOL_02412	2.25e-137	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HKEFDBOL_02413	6.44e-257	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HKEFDBOL_02414	5.75e-152	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HKEFDBOL_02415	4.83e-107	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HKEFDBOL_02416	1.53e-142	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HKEFDBOL_02417	6.21e-153	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HKEFDBOL_02418	8.09e-314	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HKEFDBOL_02419	0.0	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
HKEFDBOL_02420	2.99e-114	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HKEFDBOL_02422	1.27e-42	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HKEFDBOL_02423	6.12e-60	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKEFDBOL_02425	2.81e-76	-	-	-	EGP	-	-	-	Major Facilitator
HKEFDBOL_02426	4.45e-156	rbtT	-	-	P	ko:K13021	-	ko00000,ko02000	Major Facilitator Superfamily
HKEFDBOL_02427	5.25e-258	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HKEFDBOL_02428	4.6e-113	-	-	-	K	-	-	-	GNAT family
HKEFDBOL_02429	1.46e-161	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HKEFDBOL_02431	2.46e-48	-	-	-	-	-	-	-	-
HKEFDBOL_02432	0.0	-	-	-	P	ko:K06148	-	ko00000,ko02000	ABC transporter
HKEFDBOL_02433	1.58e-10	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HKEFDBOL_02434	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HKEFDBOL_02435	1.8e-316	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HKEFDBOL_02436	2.99e-230	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HKEFDBOL_02437	7.89e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HKEFDBOL_02438	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HKEFDBOL_02439	2.57e-223	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HKEFDBOL_02440	2.16e-205	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HKEFDBOL_02441	3.87e-241	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKEFDBOL_02442	3.32e-122	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKEFDBOL_02443	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HKEFDBOL_02444	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HKEFDBOL_02445	1.66e-217	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HKEFDBOL_02446	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HKEFDBOL_02448	3.11e-13	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HKEFDBOL_02449	1.38e-107	-	-	-	J	-	-	-	FR47-like protein
HKEFDBOL_02450	3.37e-50	-	-	-	S	-	-	-	Cytochrome B5
HKEFDBOL_02451	1.31e-213	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
HKEFDBOL_02452	5.48e-235	-	-	-	M	-	-	-	Glycosyl transferase family 8
HKEFDBOL_02453	1.91e-236	-	-	-	M	-	-	-	Glycosyl transferase family 8
HKEFDBOL_02454	7.23e-201	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
HKEFDBOL_02455	4.19e-192	-	-	-	I	-	-	-	Acyl-transferase
HKEFDBOL_02457	1.09e-46	-	-	-	-	-	-	-	-
HKEFDBOL_02459	3.98e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HKEFDBOL_02460	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKEFDBOL_02461	0.0	yycH	-	-	S	-	-	-	YycH protein
HKEFDBOL_02462	7.44e-192	yycI	-	-	S	-	-	-	YycH protein
HKEFDBOL_02463	1.19e-188	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HKEFDBOL_02464	3.17e-224	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HKEFDBOL_02465	8.64e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HKEFDBOL_02466	5.26e-171	-	-	-	H	-	-	-	Aldolase/RraA
HKEFDBOL_02467	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HKEFDBOL_02468	8.46e-197	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HKEFDBOL_02469	5.17e-249	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HKEFDBOL_02470	1.6e-59	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
HKEFDBOL_02471	1.79e-214	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
HKEFDBOL_02472	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
HKEFDBOL_02473	1.24e-93	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
HKEFDBOL_02474	9.9e-30	-	-	-	-	-	-	-	-
HKEFDBOL_02475	2.58e-189	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HKEFDBOL_02476	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKEFDBOL_02477	5.38e-125	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HKEFDBOL_02478	8.1e-87	-	-	-	S	-	-	-	Domain of unknown function DUF1828
HKEFDBOL_02479	7.91e-14	-	-	-	-	-	-	-	-
HKEFDBOL_02480	2.41e-66	-	-	-	-	-	-	-	-
HKEFDBOL_02481	1.05e-226	citR	-	-	K	-	-	-	Putative sugar-binding domain
HKEFDBOL_02482	9.28e-317	-	-	-	S	-	-	-	Putative threonine/serine exporter
HKEFDBOL_02484	5.26e-15	-	-	-	-	-	-	-	-
HKEFDBOL_02485	1.3e-115	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HKEFDBOL_02486	4.8e-224	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HKEFDBOL_02487	3.8e-80	-	-	-	-	-	-	-	-
HKEFDBOL_02488	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKEFDBOL_02489	1.8e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HKEFDBOL_02490	7.1e-311	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HKEFDBOL_02491	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HKEFDBOL_02492	5.51e-284	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HKEFDBOL_02494	4.66e-277	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HKEFDBOL_02495	1.19e-43	-	-	-	S	-	-	-	reductase
HKEFDBOL_02496	2.98e-50	-	-	-	S	-	-	-	reductase
HKEFDBOL_02497	6.32e-41	-	-	-	S	-	-	-	reductase
HKEFDBOL_02498	1.83e-190	yxeH	-	-	S	-	-	-	hydrolase
HKEFDBOL_02499	1.14e-230	gyaR	1.1.1.26, 1.1.1.399, 1.1.1.95	-	CH	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKEFDBOL_02500	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HKEFDBOL_02501	1.58e-140	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
HKEFDBOL_02502	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HKEFDBOL_02503	1.88e-309	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HKEFDBOL_02504	7.81e-101	oatA	-	-	I	-	-	-	Acyltransferase
HKEFDBOL_02505	6.82e-223	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HKEFDBOL_02506	1.18e-183	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKEFDBOL_02507	3.57e-47	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HKEFDBOL_02508	5.14e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HKEFDBOL_02509	1.52e-171	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKEFDBOL_02513	2.34e-38	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
HKEFDBOL_02514	2.2e-105	-	-	-	S	-	-	-	N-acetylmuramoyl-L-alanine amidase activity
HKEFDBOL_02516	4.79e-15	-	-	-	-	-	-	-	-
HKEFDBOL_02517	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HKEFDBOL_02518	1.25e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HKEFDBOL_02519	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HKEFDBOL_02520	5.46e-233	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HKEFDBOL_02521	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HKEFDBOL_02522	1.21e-213	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HKEFDBOL_02523	6.74e-213	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HKEFDBOL_02524	1.13e-81	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKEFDBOL_02525	1.81e-169	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HKEFDBOL_02526	7.57e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HKEFDBOL_02527	4.65e-168	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HKEFDBOL_02528	1.64e-143	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HKEFDBOL_02529	1.13e-41	-	-	-	M	-	-	-	Lysin motif
HKEFDBOL_02530	1.96e-148	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HKEFDBOL_02531	1.4e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HKEFDBOL_02532	5.45e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HKEFDBOL_02533	8.21e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HKEFDBOL_02534	3.38e-291	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HKEFDBOL_02535	2e-299	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKEFDBOL_02536	2.95e-123	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HKEFDBOL_02537	1.87e-170	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HKEFDBOL_02538	7.24e-42	yxaM	-	-	EGP	-	-	-	Major facilitator Superfamily
HKEFDBOL_02539	1.5e-150	-	-	-	S	-	-	-	F420-0:Gamma-glutamyl ligase
HKEFDBOL_02540	1.83e-103	-	-	-	S	-	-	-	AAA domain
HKEFDBOL_02541	9.82e-80	-	-	-	F	-	-	-	NUDIX domain
HKEFDBOL_02542	1.05e-176	-	-	-	F	-	-	-	Phosphorylase superfamily
HKEFDBOL_02543	6.64e-185	-	-	-	F	-	-	-	Phosphorylase superfamily
HKEFDBOL_02544	2.16e-193	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
HKEFDBOL_02545	8.49e-85	-	-	-	E	-	-	-	amino acid
HKEFDBOL_02546	6.08e-161	yagE	-	-	E	-	-	-	Amino acid permease
HKEFDBOL_02547	9.58e-112	-	3.4.21.96	-	S	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	SLAP domain
HKEFDBOL_02548	1.22e-129	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKEFDBOL_02552	1.38e-132	-	-	-	K	-	-	-	Peptidase S24-like
HKEFDBOL_02559	2.23e-29	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HKEFDBOL_02563	3.77e-106	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKEFDBOL_02564	1.02e-102	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
HKEFDBOL_02565	1.93e-32	-	-	-	G	-	-	-	Peptidase_C39 like family
HKEFDBOL_02566	2.16e-207	-	-	-	M	-	-	-	NlpC/P60 family
HKEFDBOL_02567	6.67e-115	-	-	-	G	-	-	-	Peptidase_C39 like family
HKEFDBOL_02568	1.09e-223	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HKEFDBOL_02569	1.19e-114	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HKEFDBOL_02570	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKEFDBOL_02571	1.05e-222	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HKEFDBOL_02572	1.16e-207	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HKEFDBOL_02573	1.43e-125	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HKEFDBOL_02574	7.23e-244	ysdE	-	-	P	-	-	-	Citrate transporter
HKEFDBOL_02575	3.34e-92	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HKEFDBOL_02576	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
HKEFDBOL_02577	9.69e-25	-	-	-	-	-	-	-	-
HKEFDBOL_02580	2.78e-131	-	-	-	M	-	-	-	hydrolase, family 25
HKEFDBOL_02581	1.33e-201	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKEFDBOL_02582	5.13e-287	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HKEFDBOL_02583	1.8e-143	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HKEFDBOL_02584	8.83e-187	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HKEFDBOL_02585	9.85e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HKEFDBOL_02586	3.67e-88	-	-	-	P	-	-	-	NhaP-type Na H and K H
HKEFDBOL_02587	7.2e-49	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HKEFDBOL_02588	2.4e-118	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HKEFDBOL_02589	2.15e-198	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HKEFDBOL_02590	1e-168	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKEFDBOL_02591	1.5e-195	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HKEFDBOL_02592	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKEFDBOL_02593	8.35e-315	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HKEFDBOL_02594	2.09e-180	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
HKEFDBOL_02595	4.67e-116	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HKEFDBOL_02596	1.4e-313	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HKEFDBOL_02597	9.4e-232	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HKEFDBOL_02598	9.11e-110	-	-	-	C	-	-	-	Aldo keto reductase
HKEFDBOL_02599	9.44e-63	-	-	-	M	-	-	-	LysM domain protein
HKEFDBOL_02600	1.8e-36	-	-	-	M	-	-	-	LysM domain protein
HKEFDBOL_02601	2.15e-194	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HKEFDBOL_02602	7.64e-88	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKEFDBOL_02603	2.95e-84	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKEFDBOL_02604	1.31e-16	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HKEFDBOL_02605	3.03e-145	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HKEFDBOL_02606	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HKEFDBOL_02607	7.88e-121	-	-	-	C	-	-	-	Pyridoxamine 5'-phosphate oxidase
HKEFDBOL_02608	0.0	-	-	-	E	-	-	-	Amino acid permease
HKEFDBOL_02609	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
HKEFDBOL_02610	4.97e-311	ynbB	-	-	P	-	-	-	aluminum resistance
HKEFDBOL_02611	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HKEFDBOL_02612	3.6e-106	-	-	-	C	-	-	-	Flavodoxin
HKEFDBOL_02613	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
HKEFDBOL_02614	2.25e-241	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HKEFDBOL_02615	5.94e-148	-	-	-	I	-	-	-	Acid phosphatase homologues
HKEFDBOL_02616	1.35e-67	yvbK	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKEFDBOL_02617	1.12e-149	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HKEFDBOL_02618	1.59e-259	pbpX1	-	-	V	-	-	-	Beta-lactamase
HKEFDBOL_02619	3.1e-127	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HKEFDBOL_02620	7.89e-124	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HKEFDBOL_02621	1.87e-290	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HKEFDBOL_02622	5.74e-108	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKEFDBOL_02623	0.0	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HKEFDBOL_02624	1.38e-242	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
HKEFDBOL_02625	2.76e-86	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HKEFDBOL_02626	9.63e-204	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKEFDBOL_02627	2.02e-137	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKEFDBOL_02628	4.21e-129	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HKEFDBOL_02629	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HKEFDBOL_02631	5.3e-233	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKEFDBOL_02632	8.14e-222	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKEFDBOL_02640	9.21e-19	-	-	-	-	-	-	-	-
HKEFDBOL_02641	4.22e-76	-	-	-	-	-	-	-	-
HKEFDBOL_02643	1.34e-13	-	-	-	S	-	-	-	sequence-specific DNA binding
HKEFDBOL_02645	1.28e-29	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKEFDBOL_02647	1.38e-114	-	-	-	S	-	-	-	AntA/AntB antirepressor
HKEFDBOL_02653	2.36e-08	-	-	-	K	-	-	-	DNA-binding protein
HKEFDBOL_02655	1.63e-62	-	-	-	-	-	-	-	-
HKEFDBOL_02657	5.94e-73	-	-	-	S	-	-	-	Protein of unknown function (DUF1071)
HKEFDBOL_02658	2.55e-40	-	-	-	S	-	-	-	Conserved phage C-terminus (Phg_2220_C)
HKEFDBOL_02659	6.52e-64	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
HKEFDBOL_02665	5.88e-43	-	-	-	S	-	-	-	VRR_NUC
HKEFDBOL_02667	1.51e-10	-	-	-	-	-	-	-	-
HKEFDBOL_02675	8.27e-46	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
HKEFDBOL_02676	7.69e-16	-	-	-	N	-	-	-	HicA toxin of bacterial toxin-antitoxin,
HKEFDBOL_02677	1.27e-47	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
HKEFDBOL_02678	9.32e-289	-	-	-	S	-	-	-	Terminase-like family
HKEFDBOL_02679	6.56e-176	-	-	-	S	ko:K09961	-	ko00000	Protein of unknown function (DUF1073)
HKEFDBOL_02680	2.5e-121	-	-	-	S	-	-	-	Phage Mu protein F like protein
HKEFDBOL_02682	1.13e-32	-	-	-	S	-	-	-	HNH endonuclease
HKEFDBOL_02683	2.56e-30	-	-	-	S	-	-	-	Lysin motif
HKEFDBOL_02684	3.7e-130	-	-	-	S	ko:K09960	-	ko00000	Uncharacterized protein conserved in bacteria (DUF2213)
HKEFDBOL_02685	1.78e-76	-	-	-	-	-	-	-	-
HKEFDBOL_02686	7.46e-181	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2184)
HKEFDBOL_02688	4.4e-96	-	-	-	-	-	-	-	-
HKEFDBOL_02689	7.32e-59	-	-	-	-	-	-	-	-
HKEFDBOL_02690	7.95e-69	-	-	-	-	-	-	-	-
HKEFDBOL_02691	7.86e-194	-	-	-	S	-	-	-	Protein of unknown function (DUF3383)
HKEFDBOL_02692	1.33e-73	-	-	-	-	-	-	-	-
HKEFDBOL_02695	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
HKEFDBOL_02696	6.7e-68	-	-	-	M	-	-	-	LysM domain
HKEFDBOL_02697	4.87e-61	-	-	-	-	-	-	-	-
HKEFDBOL_02698	3.16e-128	-	-	-	-	-	-	-	-
HKEFDBOL_02699	4.6e-63	-	-	-	-	-	-	-	-
HKEFDBOL_02700	1.37e-42	-	-	-	-	-	-	-	-
HKEFDBOL_02701	2.41e-157	-	-	-	S	-	-	-	Baseplate J-like protein
HKEFDBOL_02705	1.14e-88	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HKEFDBOL_02707	3.02e-26	-	-	-	-	-	-	-	-
HKEFDBOL_02708	1e-45	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKEFDBOL_02709	1.43e-80	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
HKEFDBOL_02710	5.93e-302	XK27_01810	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HKEFDBOL_02712	0.0	-	-	-	S	-	-	-	SLAP domain
HKEFDBOL_02713	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	DEAD/DEAH box helicase
HKEFDBOL_02714	1.35e-208	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
HKEFDBOL_02715	5.22e-54	-	-	-	S	-	-	-	RloB-like protein
HKEFDBOL_02716	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HKEFDBOL_02717	2.08e-118	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HKEFDBOL_02718	4.81e-77	-	-	-	S	-	-	-	SIR2-like domain
HKEFDBOL_02720	3.05e-45	-	-	-	S	ko:K06915	-	ko00000	Domain of unknown function DUF87
HKEFDBOL_02721	9.86e-146	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HKEFDBOL_02722	8.81e-40	-	-	-	M	-	-	-	Mycoplasma protein of unknown function, DUF285
HKEFDBOL_02724	1.61e-70	-	-	-	-	-	-	-	-
HKEFDBOL_02725	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HKEFDBOL_02726	3.16e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HKEFDBOL_02727	3.24e-221	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HKEFDBOL_02728	4.13e-255	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HKEFDBOL_02729	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HKEFDBOL_02730	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HKEFDBOL_02731	2.06e-88	-	-	-	-	-	-	-	-
HKEFDBOL_02732	1.15e-204	-	-	-	S	-	-	-	EDD domain protein, DegV family
HKEFDBOL_02733	1.76e-30	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKEFDBOL_02734	0.0	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HKEFDBOL_02735	1.24e-258	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HKEFDBOL_02736	1.5e-90	-	-	-	-	-	-	-	-
HKEFDBOL_02737	4.36e-142	XK27_00160	-	-	S	-	-	-	Domain of unknown function (DUF5052)
HKEFDBOL_02738	3.35e-269	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25