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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MHAKHEAG_00001	1.71e-138	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MHAKHEAG_00002	6.65e-314	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MHAKHEAG_00003	8.01e-277	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MHAKHEAG_00004	2.9e-231	-	-	-	L	-	-	-	Excalibur calcium-binding domain
MHAKHEAG_00005	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MHAKHEAG_00006	7.09e-120	-	-	-	D	-	-	-	nuclear chromosome segregation
MHAKHEAG_00007	2.23e-164	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MHAKHEAG_00008	9.04e-186	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MHAKHEAG_00009	7.85e-241	yfiH	-	-	Q	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
MHAKHEAG_00010	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32 C-terminal domain
MHAKHEAG_00013	1.95e-128	-	-	-	-	-	-	-	-
MHAKHEAG_00014	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative DNA-binding domain
MHAKHEAG_00015	2.11e-69	-	-	-	L	-	-	-	PFAM Integrase catalytic
MHAKHEAG_00016	7.82e-278	-	-	-	L	-	-	-	PFAM Integrase catalytic
MHAKHEAG_00017	4.85e-185	istB	-	-	L	-	-	-	IstB-like ATP binding protein
MHAKHEAG_00018	3.67e-82	-	-	-	D	-	-	-	MobA/MobL family
MHAKHEAG_00019	1.18e-99	-	-	-	-	-	-	-	-
MHAKHEAG_00021	9.62e-218	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
MHAKHEAG_00023	3.22e-114	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
MHAKHEAG_00024	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
MHAKHEAG_00025	0.0	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MHAKHEAG_00026	6.52e-289	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MHAKHEAG_00027	2.22e-231	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MHAKHEAG_00028	1.06e-57	pacL	3.6.3.8, 3.6.3.9	-	P	ko:K01537,ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	ko00000,ko00001,ko01000,ko04147	ATPase, P-type transporting, HAD superfamily, subfamily IC
MHAKHEAG_00029	2.93e-298	-	-	-	T	-	-	-	Histidine kinase
MHAKHEAG_00030	2.19e-153	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MHAKHEAG_00031	4.91e-150	-	-	-	P	ko:K07220	-	ko00000	Protein of unknown function DUF47
MHAKHEAG_00032	7.55e-243	pitB	-	-	P	ko:K03306	-	ko00000	Phosphate transporter family
MHAKHEAG_00033	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
MHAKHEAG_00034	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MHAKHEAG_00035	1.53e-33	-	-	-	-	-	-	-	-
MHAKHEAG_00036	1.48e-232	-	-	-	-	-	-	-	-
MHAKHEAG_00037	5.06e-46	-	-	-	L	-	-	-	Transposase
MHAKHEAG_00038	2.88e-60	-	-	-	L	-	-	-	Integrase core domain
MHAKHEAG_00040	4.36e-237	-	-	-	S	-	-	-	Protein of unknown function DUF262
MHAKHEAG_00041	2.29e-152	-	-	-	S	-	-	-	Protein of unknown function (DUF3800)
MHAKHEAG_00042	1.76e-18	-	-	-	-	-	-	-	-
MHAKHEAG_00043	1.46e-37	-	-	-	-	-	-	-	-
MHAKHEAG_00044	7.78e-59	-	-	-	S	-	-	-	Protein of unknown function (DUF1294)
MHAKHEAG_00045	3.84e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF1294)
MHAKHEAG_00048	2.81e-157	-	-	-	-	-	-	-	-
MHAKHEAG_00049	3.97e-116	-	-	-	S	-	-	-	Domain of unknown function (DUF1846)
MHAKHEAG_00050	0.0	pta	2.3.1.8	-	C	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphate acetyltransferase
MHAKHEAG_00051	1.39e-296	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MHAKHEAG_00052	0.0	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MHAKHEAG_00053	1.07e-143	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Peptidase family S51
MHAKHEAG_00054	6.7e-93	-	-	-	L	-	-	-	Phage integrase family
MHAKHEAG_00055	2.57e-67	-	-	-	L	-	-	-	Phage integrase family
MHAKHEAG_00057	8.41e-280	-	-	-	-	-	-	-	-
MHAKHEAG_00058	0.0	glgX	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
MHAKHEAG_00059	5.78e-162	-	-	-	L	-	-	-	NUDIX domain
MHAKHEAG_00060	5.17e-219	-	-	-	L	-	-	-	NIF3 (NGG1p interacting factor 3)
MHAKHEAG_00061	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MHAKHEAG_00062	5.44e-161	pdtaR	-	-	T	ko:K22010	-	ko00000,ko00002,ko02022	Response regulator receiver domain protein
MHAKHEAG_00064	1.71e-142	aspA	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
MHAKHEAG_00065	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
MHAKHEAG_00066	1.68e-229	terC	-	-	P	ko:K05794	-	ko00000	Integral membrane protein, TerC family
MHAKHEAG_00067	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MHAKHEAG_00068	4.53e-139	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MHAKHEAG_00069	0.0	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MHAKHEAG_00070	1.41e-209	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MHAKHEAG_00071	1.55e-232	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
MHAKHEAG_00072	2.33e-209	-	-	-	P	ko:K02074	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MHAKHEAG_00073	2.15e-177	znuB	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
MHAKHEAG_00074	3.64e-108	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MHAKHEAG_00075	1.99e-131	carD	-	-	K	ko:K07736	-	ko00000,ko03000	CarD-like/TRCF domain
MHAKHEAG_00076	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MHAKHEAG_00077	9.32e-164	cseB	-	-	T	-	-	-	Response regulator receiver domain protein
MHAKHEAG_00078	2.06e-259	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
MHAKHEAG_00079	3.2e-93	umuD	-	-	KT	ko:K03503	-	ko00000,ko01000,ko01002,ko03400	Peptidase S24-like
MHAKHEAG_00080	3.82e-167	pyrE_1	-	-	S	-	-	-	Phosphoribosyl transferase domain
MHAKHEAG_00081	2.33e-200	-	-	-	T	-	-	-	Eukaryotic phosphomannomutase
MHAKHEAG_00082	1.05e-85	-	-	-	S	-	-	-	Zincin-like metallopeptidase
MHAKHEAG_00083	0.0	-	-	-	-	-	-	-	-
MHAKHEAG_00084	0.0	-	-	-	S	-	-	-	Glycosyl transferase, family 2
MHAKHEAG_00085	2.82e-72	whiB2	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
MHAKHEAG_00086	0.0	lytR2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
MHAKHEAG_00087	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
MHAKHEAG_00088	6.69e-61	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
MHAKHEAG_00089	0.0	pdtaS	2.7.13.3	-	T	ko:K00936	-	ko00000,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
MHAKHEAG_00090	5.58e-193	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
MHAKHEAG_00091	2.65e-139	-	-	-	-	-	-	-	-
MHAKHEAG_00092	1.67e-104	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MHAKHEAG_00093	8.53e-95	fkbP	5.2.1.8	-	G	ko:K01802	-	ko00000,ko01000	Peptidyl-prolyl cis-trans
MHAKHEAG_00094	0.0	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
MHAKHEAG_00095	4.4e-126	-	-	-	-	-	-	-	-
MHAKHEAG_00097	2.41e-233	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
MHAKHEAG_00098	3.62e-137	-	-	-	S	ko:K09009	-	ko00000	Protein of unknown function (DUF501)
MHAKHEAG_00099	1.03e-131	-	-	-	D	-	-	-	Septum formation initiator
MHAKHEAG_00100	7.41e-315	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MHAKHEAG_00101	2.04e-194	pabC	2.6.1.42, 2.6.1.85, 4.1.3.38	-	E	ko:K00826,ko:K01665,ko:K02619,ko:K03342	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	branched-chain-amino-acid transaminase activity
MHAKHEAG_00102	0.0	pabB	2.6.1.85, 4.1.3.27, 4.1.3.38	-	EH	ko:K01657,ko:K01665,ko:K03342,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000,ko01007	chorismate binding enzyme
MHAKHEAG_00103	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MHAKHEAG_00104	3.48e-146	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MHAKHEAG_00105	1.45e-123	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
MHAKHEAG_00106	1.97e-186	rfbB2	3.6.3.40	-	GM	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MHAKHEAG_00107	1.4e-193	-	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
MHAKHEAG_00108	1.21e-252	-	-	-	GM	-	-	-	GDP-mannose 4,6 dehydratase
MHAKHEAG_00109	1.82e-165	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MHAKHEAG_00111	3.3e-281	-	-	-	I	ko:K13663	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
MHAKHEAG_00112	0.0	-	2.7.8.14, 2.7.8.47	-	M	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MHAKHEAG_00113	5.02e-264	-	2.7.8.14, 2.7.8.47	-	M	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MHAKHEAG_00114	0.0	-	-	-	S	ko:K09118	-	ko00000	Uncharacterised protein family (UPF0182)
MHAKHEAG_00115	6.64e-296	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
MHAKHEAG_00116	5.63e-253	-	-	-	-	-	-	-	-
MHAKHEAG_00117	2.07e-195	-	-	-	V	ko:K02003,ko:K09810	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MHAKHEAG_00118	3.07e-244	-	-	-	V	-	-	-	N-Acetylmuramoyl-L-alanine amidase
MHAKHEAG_00119	0.0	argE	-	-	E	-	-	-	Peptidase dimerisation domain
MHAKHEAG_00120	2.94e-134	-	-	-	S	-	-	-	Protein of unknown function (DUF3043)
MHAKHEAG_00121	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MHAKHEAG_00122	2.47e-181	-	-	-	S	-	-	-	Domain of unknown function (DUF4191)
MHAKHEAG_00123	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MHAKHEAG_00124	1.34e-24	-	-	-	-	-	-	-	-
MHAKHEAG_00126	8.73e-21	-	-	-	-	-	-	-	-
MHAKHEAG_00130	2.02e-203	-	-	-	S	-	-	-	Protein conserved in bacteria
MHAKHEAG_00131	8.24e-270	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MHAKHEAG_00132	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MHAKHEAG_00133	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
MHAKHEAG_00134	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MHAKHEAG_00135	3.23e-90	-	2.8.2.22	-	S	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
MHAKHEAG_00136	3.64e-177	-	-	-	P	ko:K16784	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MHAKHEAG_00137	3.37e-270	-	-	-	E	-	-	-	Aminotransferase class I and II
MHAKHEAG_00138	2.21e-178	ppgK	2.7.1.2, 2.7.1.63	-	GK	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MHAKHEAG_00139	1.39e-135	-	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MHAKHEAG_00140	0.0	-	-	-	GP	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MHAKHEAG_00141	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MHAKHEAG_00142	0.0	rarA	-	-	L	ko:K07478	-	ko00000	Recombination factor protein RarA
MHAKHEAG_00143	0.0	-	-	-	L	-	-	-	DEAD DEAH box helicase
MHAKHEAG_00144	1.68e-253	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
MHAKHEAG_00145	6.57e-253	gluD	-	-	E	ko:K10007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MHAKHEAG_00146	2.97e-144	gluC	-	-	E	ko:K10006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MHAKHEAG_00147	1.45e-196	gluB	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MHAKHEAG_00148	9.73e-179	gluA	-	-	E	ko:K10008	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding protein of ABC transporter for glutamate K02028
MHAKHEAG_00149	3.09e-118	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
MHAKHEAG_00150	4.51e-107	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MHAKHEAG_00151	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MHAKHEAG_00152	0.0	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
MHAKHEAG_00153	5.86e-299	-	-	-	S	-	-	-	Domain of Unknown Function (DUF349)
MHAKHEAG_00157	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
MHAKHEAG_00158	9.86e-237	uspA	-	-	T	-	-	-	Belongs to the universal stress protein A family
MHAKHEAG_00159	1.49e-251	-	-	-	S	-	-	-	Protein of unknown function (DUF3027)
MHAKHEAG_00160	7.13e-87	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
MHAKHEAG_00161	0.0	phoR	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
MHAKHEAG_00162	1.23e-171	phoP	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulator receiver domain protein
MHAKHEAG_00163	6.66e-222	-	-	-	-	-	-	-	-
MHAKHEAG_00164	8.25e-53	-	-	-	S	-	-	-	Proteins of 100 residues with WXG
MHAKHEAG_00165	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MHAKHEAG_00166	2.97e-41	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
MHAKHEAG_00167	4.24e-105	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
MHAKHEAG_00168	2.11e-185	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MHAKHEAG_00169	1.22e-251	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
MHAKHEAG_00170	1.13e-225	-	-	-	S	-	-	-	Protein of unknown function DUF58
MHAKHEAG_00171	3.59e-121	-	-	-	-	-	-	-	-
MHAKHEAG_00172	1.86e-245	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
MHAKHEAG_00173	2.85e-198	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
MHAKHEAG_00174	2.27e-117	-	-	-	-	-	-	-	-
MHAKHEAG_00176	0.0	-	-	-	S	-	-	-	PGAP1-like protein
MHAKHEAG_00177	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminal
MHAKHEAG_00178	0.0	-	-	-	S	-	-	-	Lysylphosphatidylglycerol synthase TM region
MHAKHEAG_00179	4.7e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
MHAKHEAG_00180	0.0	pafA	6.3.1.19	-	O	ko:K13571	-	ko00000,ko00002,ko01000,ko03051	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MHAKHEAG_00181	1.05e-28	pup	-	-	S	ko:K13570	-	ko00000,ko04121	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
MHAKHEAG_00182	3.29e-202	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
MHAKHEAG_00183	0.0	dop	3.5.1.119	-	S	ko:K20814	-	ko00000,ko01000,ko03051	Pup-ligase protein
MHAKHEAG_00184	0.0	arc	-	-	O	ko:K13527	ko03050,map03050	ko00000,ko00001,ko00002,ko03051	AAA ATPase forming ring-shaped complexes
MHAKHEAG_00185	2.25e-178	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
MHAKHEAG_00186	1.29e-233	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MHAKHEAG_00187	3.86e-174	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MHAKHEAG_00188	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MHAKHEAG_00189	7.86e-285	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MHAKHEAG_00190	9.87e-70	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MHAKHEAG_00191	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
MHAKHEAG_00192	7.42e-212	-	-	-	S	-	-	-	Protein conserved in bacteria
MHAKHEAG_00193	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MHAKHEAG_00194	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
MHAKHEAG_00195	4.91e-144	-	-	-	-	-	-	-	-
MHAKHEAG_00196	2.63e-313	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHAKHEAG_00197	1.87e-172	-	-	-	S	-	-	-	Protein of unknown function (DUF3159)
MHAKHEAG_00198	3.78e-196	-	-	-	S	-	-	-	Protein of unknown function (DUF3710)
MHAKHEAG_00199	5.8e-215	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
MHAKHEAG_00200	0.0	-	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MHAKHEAG_00201	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
MHAKHEAG_00202	0.0	oppD	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MHAKHEAG_00203	5.29e-212	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
MHAKHEAG_00204	4.8e-226	oppB1	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MHAKHEAG_00205	2.74e-235	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
MHAKHEAG_00206	2.67e-56	-	-	-	-	-	-	-	-
MHAKHEAG_00207	2.1e-245	tyrA	1.3.1.12	-	E	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
MHAKHEAG_00208	7.12e-254	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
MHAKHEAG_00209	1.83e-109	-	-	-	-	-	-	-	-
MHAKHEAG_00210	0.0	typA	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
MHAKHEAG_00211	8.76e-299	iscS1	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
MHAKHEAG_00212	9.56e-211	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
MHAKHEAG_00213	0.0	nadB	1.4.3.16, 2.4.2.19	-	H	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
MHAKHEAG_00214	0.0	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MHAKHEAG_00215	6.03e-191	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX hydrolase
MHAKHEAG_00216	6.08e-145	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MHAKHEAG_00217	8.34e-194	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MHAKHEAG_00218	1.31e-194	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
MHAKHEAG_00219	9.73e-228	xerD	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	recombinase XerD
MHAKHEAG_00220	5.46e-81	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MHAKHEAG_00221	3.31e-35	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
MHAKHEAG_00222	2.16e-137	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MHAKHEAG_00223	1.4e-10	-	-	-	S	-	-	-	Spermine/spermidine synthase domain
MHAKHEAG_00224	3.41e-172	-	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamin pyrophosphokinase, vitamin B1 binding domain
MHAKHEAG_00225	3.39e-254	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MHAKHEAG_00226	6.06e-119	ybaK	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MHAKHEAG_00228	5.38e-230	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MHAKHEAG_00229	7.58e-248	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MHAKHEAG_00230	3.35e-84	-	-	-	-	-	-	-	-
MHAKHEAG_00231	9.94e-149	sigH	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MHAKHEAG_00232	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MHAKHEAG_00233	1.26e-244	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
MHAKHEAG_00234	3.1e-289	-	2.6.1.33	-	M	ko:K20429	-	ko00000,ko01000	DegT/DnrJ/EryC1/StrS aminotransferase family
MHAKHEAG_00235	6.99e-307	-	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp
MHAKHEAG_00236	2.31e-174	-	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MHAKHEAG_00237	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
MHAKHEAG_00238	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
MHAKHEAG_00240	7.52e-126	-	-	-	F	-	-	-	NUDIX domain
MHAKHEAG_00241	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
MHAKHEAG_00242	0.0	-	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MHAKHEAG_00243	7.55e-249	dppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MHAKHEAG_00244	3.06e-242	dppB	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MHAKHEAG_00245	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
MHAKHEAG_00246	4.41e-309	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
MHAKHEAG_00247	5.93e-196	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MHAKHEAG_00248	2.39e-275	-	-	-	GK	-	-	-	ROK family
MHAKHEAG_00249	1.98e-168	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
MHAKHEAG_00250	2.53e-284	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MHAKHEAG_00251	2.87e-217	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
MHAKHEAG_00252	3.73e-301	-	-	-	G	-	-	-	Major Facilitator Superfamily
MHAKHEAG_00253	2.9e-109	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MHAKHEAG_00256	1.01e-232	ftsQ	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
MHAKHEAG_00257	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MHAKHEAG_00258	3.15e-276	murG	2.4.1.227, 6.3.2.8	GT28	M	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MHAKHEAG_00259	4.49e-297	ftsW	2.4.1.227	GT28	D	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	Belongs to the SEDS family
MHAKHEAG_00260	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MHAKHEAG_00261	8.76e-261	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MHAKHEAG_00262	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MHAKHEAG_00263	2.48e-231	-	-	-	M	-	-	-	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MHAKHEAG_00264	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding protein, transpeptidase domain protein
MHAKHEAG_00265	1.96e-97	-	-	-	D	-	-	-	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MHAKHEAG_00266	6.21e-246	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MHAKHEAG_00267	8.85e-118	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MHAKHEAG_00268	0.0	-	-	-	L	-	-	-	DNA helicase
MHAKHEAG_00269	5.58e-291	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
MHAKHEAG_00270	2.55e-107	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MHAKHEAG_00271	3.99e-64	-	-	-	M	-	-	-	Lysin motif
MHAKHEAG_00272	3.03e-166	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MHAKHEAG_00273	2.62e-211	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHAKHEAG_00274	1.88e-224	ldh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MHAKHEAG_00275	0.0	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MHAKHEAG_00276	3.25e-222	-	-	-	-	-	-	-	-
MHAKHEAG_00277	2.51e-157	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
MHAKHEAG_00278	0.0	hrpA	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Helicase associated domain (HA2) Add an annotation
MHAKHEAG_00279	1.2e-241	-	-	-	M	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
MHAKHEAG_00280	5.77e-35	-	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major facilitator Superfamily
MHAKHEAG_00281	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
MHAKHEAG_00282	0.0	glnA2	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MHAKHEAG_00283	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2252)
MHAKHEAG_00284	4.81e-167	hisA	5.3.1.16, 5.3.1.24	-	E	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
MHAKHEAG_00285	2.24e-155	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MHAKHEAG_00286	1.84e-151	-	-	-	-	-	-	-	-
MHAKHEAG_00287	1.08e-145	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
MHAKHEAG_00288	1.85e-285	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MHAKHEAG_00289	0.0	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MHAKHEAG_00290	2.91e-214	-	-	-	S	-	-	-	Protein conserved in bacteria
MHAKHEAG_00293	1.19e-97	-	-	-	S	-	-	-	Domain of unknown function (DUF4186)
MHAKHEAG_00294	3.65e-222	dkgV	-	-	C	-	-	-	Aldo/keto reductase family
MHAKHEAG_00295	5.5e-199	-	-	-	S	-	-	-	Aldo/keto reductase family
MHAKHEAG_00296	1.24e-258	-	-	-	K	-	-	-	WYL domain
MHAKHEAG_00298	5e-05	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MHAKHEAG_00299	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
MHAKHEAG_00300	1.9e-62	-	-	-	J	ko:K07574	-	ko00000,ko03009	CRS1_YhbY
MHAKHEAG_00301	1.63e-155	-	-	-	S	-	-	-	zinc-ribbon domain
MHAKHEAG_00302	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
MHAKHEAG_00303	1.11e-53	cscA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
MHAKHEAG_00304	1.32e-23	fosC	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
MHAKHEAG_00305	1.65e-245	-	-	-	S	-	-	-	Domain of unknown function (DUF1963)
MHAKHEAG_00306	2.53e-198	uppS	2.5.1.31, 2.5.1.86, 2.5.1.88	-	H	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MHAKHEAG_00307	1.5e-184	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MHAKHEAG_00308	0.0	-	-	-	I	-	-	-	acetylesterase activity
MHAKHEAG_00309	1.6e-298	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MHAKHEAG_00310	1.45e-280	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MHAKHEAG_00311	2.84e-313	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
MHAKHEAG_00313	3.79e-16	-	-	-	L	-	-	-	PFAM Integrase catalytic
MHAKHEAG_00314	9.38e-13	-	-	-	-	-	-	-	-
MHAKHEAG_00315	1.07e-115	-	-	-	-	-	-	-	-
MHAKHEAG_00317	1.29e-186	-	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	RNA pseudouridylate synthase
MHAKHEAG_00318	1.38e-103	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MHAKHEAG_00319	5e-285	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain protein
MHAKHEAG_00320	4.29e-203	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in cellular division
MHAKHEAG_00321	8.34e-299	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Cell division ATP-binding protein FtsE
MHAKHEAG_00322	5.51e-263	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MHAKHEAG_00323	3.72e-220	dapD	2.3.1.117	-	E	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
MHAKHEAG_00324	1.25e-82	-	-	-	-	-	-	-	-
MHAKHEAG_00326	1.89e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MHAKHEAG_00327	4.6e-148	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MHAKHEAG_00328	1.65e-191	-	-	-	V	-	-	-	DivIVA protein
MHAKHEAG_00329	1.35e-56	-	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
MHAKHEAG_00330	9.4e-105	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MHAKHEAG_00331	3.27e-294	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MHAKHEAG_00332	8.15e-315	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MHAKHEAG_00333	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
MHAKHEAG_00334	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Domain of unknown function (DUF4982)
MHAKHEAG_00335	3.39e-200	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MHAKHEAG_00336	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MHAKHEAG_00337	1.62e-110	-	-	-	-	-	-	-	-
MHAKHEAG_00338	1.98e-290	-	-	-	O	ko:K13525	ko04141,ko05134,map04141,map05134	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	AAA domain (Cdc48 subfamily)
MHAKHEAG_00339	1.21e-209	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MHAKHEAG_00340	2.08e-79	-	-	-	S	-	-	-	Thiamine-binding protein
MHAKHEAG_00341	5.62e-179	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MHAKHEAG_00342	4.52e-86	-	-	-	S	-	-	-	Protein of unknown function (DUF3052)
MHAKHEAG_00343	2.91e-193	sdrC	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MHAKHEAG_00344	0.0	-	-	-	S	-	-	-	Zincin-like metallopeptidase
MHAKHEAG_00345	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MHAKHEAG_00346	0.0	mphA	-	-	S	-	-	-	Aminoglycoside phosphotransferase
MHAKHEAG_00347	9.31e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF3107)
MHAKHEAG_00348	2.09e-212	PPA1328	3.1.3.97, 3.1.4.57	-	S	ko:K07053,ko:K20859	ko00440,map00440	ko00000,ko00001,ko01000	DNA polymerase alpha chain like domain
MHAKHEAG_00349	4.82e-147	-	-	-	S	-	-	-	Vitamin K epoxide reductase
MHAKHEAG_00350	4.94e-214	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
MHAKHEAG_00351	5.49e-196	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MHAKHEAG_00352	1.31e-219	-	-	-	S	-	-	-	Patatin-like phospholipase
MHAKHEAG_00353	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
MHAKHEAG_00354	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MHAKHEAG_00355	6.07e-116	-	-	-	K	-	-	-	MarR family
MHAKHEAG_00356	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
MHAKHEAG_00357	0.0	egtA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Glutamate-cysteine ligase family 2(GCS2)
MHAKHEAG_00358	4.55e-212	-	-	-	-	-	-	-	-
MHAKHEAG_00359	0.0	hgdC	-	-	I	-	-	-	CoA enzyme activase uncharacterised domain (DUF2229)
MHAKHEAG_00361	5.91e-179	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MHAKHEAG_00362	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
MHAKHEAG_00363	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHAKHEAG_00364	1.47e-56	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHAKHEAG_00365	2.23e-258	-	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
MHAKHEAG_00367	5.95e-05	malR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MHAKHEAG_00368	4.73e-234	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
MHAKHEAG_00369	0.0	-	-	-	OP	-	-	-	Sulfurtransferase TusA
MHAKHEAG_00370	8.74e-193	thiF	2.7.7.73, 2.7.7.80, 2.8.1.11	-	H	ko:K03148,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
MHAKHEAG_00371	4.8e-171	tmp1	-	-	S	-	-	-	Domain of unknown function (DUF4391)
MHAKHEAG_00372	1.3e-200	ppx1	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
MHAKHEAG_00373	7.65e-293	aspB	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class-V
MHAKHEAG_00374	2.43e-129	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
MHAKHEAG_00375	0.0	-	-	-	S	-	-	-	zinc finger
MHAKHEAG_00376	3.18e-160	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MHAKHEAG_00377	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MHAKHEAG_00378	0.0	vpr	-	-	O	-	-	-	Subtilase family
MHAKHEAG_00379	0.0	pepN	3.4.11.2	-	E	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Peptidase family M1 domain
MHAKHEAG_00380	0.0	rnj	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHAKHEAG_00381	6.97e-208	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MHAKHEAG_00382	1.16e-169	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MHAKHEAG_00383	1.19e-75	-	-	-	L	-	-	-	Transposase
MHAKHEAG_00384	3.22e-33	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MHAKHEAG_00385	8.46e-55	-	-	-	L	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
MHAKHEAG_00386	3.56e-86	gsiA	-	-	P	ko:K02031,ko:K02032,ko:K12371,ko:K13892	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MHAKHEAG_00387	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
MHAKHEAG_00388	2.39e-195	-	-	-	K	-	-	-	-acetyltransferase
MHAKHEAG_00389	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	Belongs to the helicase family. UvrD subfamily
MHAKHEAG_00390	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
MHAKHEAG_00391	0.0	pknK	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
MHAKHEAG_00392	0.0	-	-	-	S	-	-	-	Fibronectin type 3 domain
MHAKHEAG_00393	0.0	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
MHAKHEAG_00394	6.42e-299	-	-	-	S	-	-	-	Protein of unknown function DUF58
MHAKHEAG_00395	0.0	-	-	-	E	-	-	-	Transglutaminase-like superfamily
MHAKHEAG_00396	9.56e-211	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
MHAKHEAG_00397	1.2e-100	-	-	-	B	-	-	-	Belongs to the OprB family
MHAKHEAG_00398	5.36e-124	-	-	-	T	-	-	-	Forkhead associated domain
MHAKHEAG_00399	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHAKHEAG_00400	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHAKHEAG_00401	4.96e-126	-	-	-	-	-	-	-	-
MHAKHEAG_00402	2.13e-234	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	FES
MHAKHEAG_00403	3.46e-43	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	Putative cell wall binding repeat
MHAKHEAG_00404	6.75e-76	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	Putative cell wall binding repeat
MHAKHEAG_00405	5.27e-156	spoU	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MHAKHEAG_00406	8.76e-234	-	-	-	S	-	-	-	Membrane
MHAKHEAG_00407	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
MHAKHEAG_00408	3.23e-58	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
MHAKHEAG_00409	1.32e-308	-	-	-	EGP	-	-	-	Sugar (and other) transporter
MHAKHEAG_00410	2.4e-296	galK	2.7.1.6, 2.7.7.12	-	G	ko:K00849,ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
MHAKHEAG_00411	0.0	galT	2.7.7.12	-	C	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, N-terminal domain
MHAKHEAG_00412	7e-186	-	-	-	K	-	-	-	DeoR C terminal sensor domain
MHAKHEAG_00413	2.85e-289	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
MHAKHEAG_00414	3.02e-277	namA	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
MHAKHEAG_00415	0.0	pon1	-	-	M	-	-	-	Transglycosylase
MHAKHEAG_00416	4.67e-173	crp	-	-	K	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
MHAKHEAG_00417	8.97e-151	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
MHAKHEAG_00418	3.62e-245	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MHAKHEAG_00419	0.0	ptrB	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Peptidase, S9A B C family, catalytic domain protein
MHAKHEAG_00420	0.0	-	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2183)
MHAKHEAG_00421	2.17e-93	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
MHAKHEAG_00422	0.0	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
MHAKHEAG_00424	1.2e-204	-	-	-	I	-	-	-	Alpha/beta hydrolase family
MHAKHEAG_00425	3.88e-152	-	-	-	F	-	-	-	Domain of unknown function (DUF4916)
MHAKHEAG_00426	2.57e-78	trxA	1.8.1.9	-	O	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	ko00000,ko00001,ko01000,ko03110	Belongs to the thioredoxin family
MHAKHEAG_00427	2.49e-230	-	-	-	S	ko:K21688	-	ko00000	G5
MHAKHEAG_00428	0.0	-	-	-	-	-	-	-	-
MHAKHEAG_00429	9.03e-56	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
MHAKHEAG_00430	8.83e-147	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
MHAKHEAG_00431	1.53e-123	rfbP	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
MHAKHEAG_00432	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
MHAKHEAG_00433	2.93e-297	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
MHAKHEAG_00434	2.77e-158	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
MHAKHEAG_00435	5.17e-218	-	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
MHAKHEAG_00436	1.61e-258	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
MHAKHEAG_00437	1.79e-142	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
MHAKHEAG_00438	7.08e-148	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
MHAKHEAG_00441	4.7e-143	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MHAKHEAG_00442	2.37e-198	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MHAKHEAG_00443	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
MHAKHEAG_00445	5.12e-266	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
MHAKHEAG_00446	1.9e-169	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHAKHEAG_00447	1.03e-201	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MHAKHEAG_00448	2.33e-81	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MHAKHEAG_00449	4.86e-166	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Class II Aldolase and Adducin N-terminal domain
MHAKHEAG_00450	6.29e-220	-	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
MHAKHEAG_00451	0.0	-	2.7.1.53	-	G	ko:K00880	ko00040,ko00053,map00040,map00053	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
MHAKHEAG_00452	1.46e-283	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
MHAKHEAG_00453	8.57e-222	-	-	-	K	-	-	-	Putative sugar-binding domain
MHAKHEAG_00454	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MHAKHEAG_00455	0.0	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MHAKHEAG_00456	8.95e-74	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	Cation transporting ATPase, C-terminus
MHAKHEAG_00457	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	Cation transporting ATPase, C-terminus
MHAKHEAG_00458	4.87e-155	mgtC	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
MHAKHEAG_00460	6.19e-263	-	-	-	-	-	-	-	-
MHAKHEAG_00462	2.09e-272	-	-	-	-	-	-	-	-
MHAKHEAG_00463	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MHAKHEAG_00466	6.28e-225	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
MHAKHEAG_00467	3.97e-152	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MHAKHEAG_00468	6.69e-173	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MHAKHEAG_00469	1.17e-314	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MHAKHEAG_00471	1.26e-118	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
MHAKHEAG_00472	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
MHAKHEAG_00473	1.56e-179	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MHAKHEAG_00474	2.72e-34	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MHAKHEAG_00475	8.83e-147	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
MHAKHEAG_00476	3.01e-184	-	-	-	-	-	-	-	-
MHAKHEAG_00477	3.67e-105	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MHAKHEAG_00478	1.04e-76	-	-	-	S	-	-	-	Protein of unknown function (DUF3039)
MHAKHEAG_00479	0.0	yjjK	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter
MHAKHEAG_00480	6.63e-174	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase C26
MHAKHEAG_00481	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MHAKHEAG_00482	4.14e-212	-	-	-	P	-	-	-	Cation efflux family
MHAKHEAG_00483	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MHAKHEAG_00484	1.64e-283	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
MHAKHEAG_00485	5.28e-129	-	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
MHAKHEAG_00486	0.0	-	-	-	EK	ko:K05825,ko:K18907	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko00002,ko01000,ko01504,ko03000	Alanine-glyoxylate amino-transferase
MHAKHEAG_00487	2.4e-80	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MHAKHEAG_00488	3.56e-47	-	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
MHAKHEAG_00489	1.08e-137	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MHAKHEAG_00490	9.36e-229	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MHAKHEAG_00491	5.32e-108	-	-	-	O	-	-	-	Hsp20/alpha crystallin family
MHAKHEAG_00492	1.93e-139	-	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
MHAKHEAG_00494	3.78e-156	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Conserved hypothetical protein 95
MHAKHEAG_00495	0.0	-	-	-	U	ko:K06956	-	ko00000	Sodium:dicarboxylate symporter family
MHAKHEAG_00496	0.0	-	-	-	-	-	-	-	-
MHAKHEAG_00499	1.74e-278	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MHAKHEAG_00500	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	helicase superfamily c-terminal domain
MHAKHEAG_00501	7.42e-41	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
MHAKHEAG_00502	2.69e-256	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
MHAKHEAG_00504	7.08e-308	-	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
MHAKHEAG_00505	9.29e-168	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MHAKHEAG_00506	1.35e-12	-	-	-	T	-	-	-	Toxic component of a toxin-antitoxin (TA) module
MHAKHEAG_00507	1.77e-72	-	-	-	L	-	-	-	RelB antitoxin
MHAKHEAG_00508	4.54e-46	-	-	-	I	-	-	-	carboxylic ester hydrolase activity
MHAKHEAG_00509	1.01e-292	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MHAKHEAG_00510	2.11e-160	tam	2.1.1.144	-	S	ko:K00598	-	ko00000,ko01000	Methyltransferase domain
MHAKHEAG_00515	1.9e-45	-	-	-	-	-	-	-	-
MHAKHEAG_00517	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
MHAKHEAG_00518	4.78e-54	-	-	-	K	-	-	-	Transcriptional regulator
MHAKHEAG_00519	1.18e-85	-	-	-	S	ko:K06889	-	ko00000	alpha beta
MHAKHEAG_00521	9.14e-13	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 28 family
MHAKHEAG_00522	3.94e-294	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
MHAKHEAG_00523	1.37e-306	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MHAKHEAG_00524	1.51e-153	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MHAKHEAG_00525	2.44e-168	-	-	-	M	-	-	-	Mechanosensitive ion channel
MHAKHEAG_00526	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MHAKHEAG_00528	5.72e-199	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
MHAKHEAG_00529	2.03e-147	-	-	-	S	-	-	-	Domain of unknown function (DUF4854)
MHAKHEAG_00530	6.52e-271	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MHAKHEAG_00531	0.0	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
MHAKHEAG_00532	0.0	-	-	-	M	-	-	-	domain protein
MHAKHEAG_00533	2.45e-70	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Acylphosphatase
MHAKHEAG_00534	3.39e-188	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MHAKHEAG_00535	1.72e-247	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MHAKHEAG_00536	1.28e-174	-	-	-	M	-	-	-	Protein of unknown function (DUF3152)
MHAKHEAG_00537	3.99e-176	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MHAKHEAG_00539	3.29e-53	-	-	-	E	-	-	-	Domain of unknown function (DUF5011)
MHAKHEAG_00540	2.6e-185	istB	-	-	L	-	-	-	IstB-like ATP binding protein
MHAKHEAG_00541	5e-251	-	-	-	L	-	-	-	PFAM Integrase catalytic
MHAKHEAG_00542	9.43e-25	-	-	-	E	-	-	-	Domain of unknown function (DUF5011)
MHAKHEAG_00543	9.21e-52	-	-	-	S	-	-	-	Parallel beta-helix repeats
MHAKHEAG_00545	2.34e-92	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MHAKHEAG_00546	1.51e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MHAKHEAG_00547	1.12e-110	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
MHAKHEAG_00548	6.47e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MHAKHEAG_00549	1.51e-227	-	-	-	T	-	-	-	Pfam Adenylate and Guanylate cyclase catalytic domain
MHAKHEAG_00550	6.29e-55	-	-	-	-	-	-	-	-
MHAKHEAG_00551	2.85e-54	-	-	-	-	-	-	-	-
MHAKHEAG_00552	0.0	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MHAKHEAG_00553	1.26e-242	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MHAKHEAG_00554	0.0	-	3.2.1.97	GH101	G	ko:K17624	-	ko00000,ko01000	Glycosyl hydrolase 101 beta sandwich domain
MHAKHEAG_00555	1.73e-253	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
MHAKHEAG_00556	1.42e-278	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MHAKHEAG_00557	1.38e-227	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
MHAKHEAG_00558	1.27e-221	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
MHAKHEAG_00559	6.4e-164	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MHAKHEAG_00560	4.95e-44	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MHAKHEAG_00562	2.89e-294	aspC	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
MHAKHEAG_00563	6.1e-256	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MHAKHEAG_00564	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MHAKHEAG_00565	6.29e-274	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MHAKHEAG_00566	2.12e-53	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
MHAKHEAG_00567	1.44e-62	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MHAKHEAG_00568	0.0	rne	3.1.26.12	-	J	ko:K08300,ko:K08301	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	Ribonuclease E/G family
MHAKHEAG_00569	2e-304	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
MHAKHEAG_00570	9.55e-215	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
MHAKHEAG_00571	0.0	-	-	-	V	-	-	-	Efflux ABC transporter, permease protein
MHAKHEAG_00572	1.59e-210	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MHAKHEAG_00573	2.73e-76	-	-	-	-	-	-	-	-
MHAKHEAG_00574	5.49e-85	-	-	-	-	-	-	-	-
MHAKHEAG_00575	0.0	maf	-	-	DF	ko:K06287	-	ko00000	Maf-like protein
MHAKHEAG_00576	5.51e-239	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MHAKHEAG_00577	1.79e-304	hom	1.1.1.3, 2.7.2.4	-	E	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
MHAKHEAG_00578	0.0	nagE	2.7.1.193	-	G	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
MHAKHEAG_00579	5.94e-107	-	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MHAKHEAG_00580	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MHAKHEAG_00581	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MHAKHEAG_00582	3.93e-230	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
MHAKHEAG_00583	2.69e-82	psp1	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	Endoribonuclease L-PSP
MHAKHEAG_00584	5.51e-193	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
MHAKHEAG_00585	2.53e-240	pdxB	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHAKHEAG_00586	1.06e-197	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
MHAKHEAG_00587	1.38e-183	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	oligopeptide transport protein of the ABC superfamily, ATP-binding component
MHAKHEAG_00588	1.5e-209	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MHAKHEAG_00589	1.72e-218	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MHAKHEAG_00590	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
MHAKHEAG_00591	2.65e-184	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MHAKHEAG_00592	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MHAKHEAG_00593	3.42e-84	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	carbohydrate transport
MHAKHEAG_00594	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
MHAKHEAG_00595	4.22e-160	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
MHAKHEAG_00596	2.17e-243	-	-	-	K	-	-	-	Periplasmic binding protein domain
MHAKHEAG_00597	3.53e-25	-	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MHAKHEAG_00598	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
MHAKHEAG_00600	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MHAKHEAG_00601	4.8e-73	-	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
MHAKHEAG_00602	0.0	aldH	1.2.1.3, 1.2.99.10	-	C	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldehyde dehydrogenase family
MHAKHEAG_00603	8.77e-179	hflK	-	-	O	-	-	-	prohibitin homologues
MHAKHEAG_00604	1.81e-310	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
MHAKHEAG_00605	3.15e-298	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
MHAKHEAG_00606	0.0	nox	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
MHAKHEAG_00607	9.17e-284	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
MHAKHEAG_00608	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MHAKHEAG_00609	0.0	-	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
MHAKHEAG_00610	2.11e-249	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
MHAKHEAG_00611	2.92e-131	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease, DNA polymerase III, epsilon subunit family
MHAKHEAG_00612	0.0	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
MHAKHEAG_00613	6.17e-192	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
MHAKHEAG_00614	1.56e-186	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
MHAKHEAG_00615	0.0	pepO	3.4.24.11, 3.4.24.71	-	O	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase family M13
MHAKHEAG_00616	1.9e-154	ssb2	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
MHAKHEAG_00617	5.42e-219	-	-	-	-	-	-	-	-
MHAKHEAG_00618	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MHAKHEAG_00619	2.45e-230	-	-	-	I	-	-	-	PAP2 superfamily
MHAKHEAG_00620	2.83e-47	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
MHAKHEAG_00621	0.0	-	-	-	L	-	-	-	PIF1-like helicase
MHAKHEAG_00622	6.98e-206	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MHAKHEAG_00623	1.91e-156	orn	-	-	L	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MHAKHEAG_00624	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
MHAKHEAG_00625	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MHAKHEAG_00626	1.06e-260	rfe	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 4
MHAKHEAG_00627	7.44e-151	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
MHAKHEAG_00628	3.71e-78	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Bacterial transferase hexapeptide repeat protein
MHAKHEAG_00629	5.94e-237	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MHAKHEAG_00630	1.66e-246	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MHAKHEAG_00631	1.85e-48	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
MHAKHEAG_00633	5.15e-247	-	-	-	K	ko:K13633	-	ko00000,ko03000	helix_turn_helix, arabinose operon control protein
MHAKHEAG_00634	1.58e-208	-	-	-	G	ko:K05340	-	ko00000,ko02000	Sugar transport protein
MHAKHEAG_00635	1.92e-239	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
MHAKHEAG_00636	0.0	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	Mycolic acid cyclopropane synthetase
MHAKHEAG_00637	3.57e-144	-	-	-	-	-	-	-	-
MHAKHEAG_00638	2.66e-217	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
MHAKHEAG_00639	7.95e-189	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
MHAKHEAG_00640	0.0	-	-	-	JKL	-	-	-	helicase superfamily c-terminal domain
MHAKHEAG_00641	1.23e-210	-	-	-	EG	-	-	-	EamA-like transporter family
MHAKHEAG_00642	4.81e-185	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MHAKHEAG_00643	1.43e-188	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
MHAKHEAG_00645	7.33e-271	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MHAKHEAG_00646	0.0	-	2.5.1.49	-	H	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.98
MHAKHEAG_00647	4.43e-58	-	-	-	C	-	-	-	Aldo/keto reductase family
MHAKHEAG_00648	1.94e-94	-	-	-	EGP	-	-	-	Major facilitator superfamily
MHAKHEAG_00649	3.68e-229	glkA	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MHAKHEAG_00650	0.0	-	-	-	S	-	-	-	ATPases associated with a variety of cellular activities
MHAKHEAG_00651	2.9e-75	-	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	Major facilitator Superfamily
MHAKHEAG_00652	1.7e-200	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MHAKHEAG_00653	4.04e-149	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
MHAKHEAG_00655	7.29e-65	-	-	-	S	-	-	-	DUF218 domain
MHAKHEAG_00656	8.79e-139	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
MHAKHEAG_00657	1.54e-201	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
MHAKHEAG_00658	2.05e-146	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MHAKHEAG_00660	1.76e-161	-	-	-	-	-	-	-	-
MHAKHEAG_00661	1.66e-224	-	-	-	M	-	-	-	domain, Protein
MHAKHEAG_00662	8.64e-24	-	-	-	M	-	-	-	domain, Protein
MHAKHEAG_00663	0.0	yjjK	-	-	S	-	-	-	ATP-binding cassette protein, ChvD family
MHAKHEAG_00664	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	hydrolase family 20, catalytic
MHAKHEAG_00665	1.88e-219	tesB	-	-	I	ko:K10805	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	Thioesterase-like superfamily
MHAKHEAG_00666	2.35e-107	-	-	-	S	-	-	-	Protein of unknown function (DUF3180)
MHAKHEAG_00667	0.0	folK	2.7.6.3, 4.1.2.25	-	H	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MHAKHEAG_00668	1.12e-210	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MHAKHEAG_00669	2.05e-130	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
MHAKHEAG_00670	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MHAKHEAG_00671	2.65e-127	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
MHAKHEAG_00672	3.48e-269	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MHAKHEAG_00673	0.0	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-Ala-D-Ala carboxypeptidase 3 (S13) family
MHAKHEAG_00674	0.0	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
MHAKHEAG_00675	2.26e-215	natA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MHAKHEAG_00676	3.97e-295	-	-	-	M	-	-	-	Glycosyl transferase family 21
MHAKHEAG_00677	0.0	-	-	-	S	-	-	-	AI-2E family transporter
MHAKHEAG_00678	1.89e-227	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MHAKHEAG_00679	1.48e-271	fucO	1.1.1.77, 1.1.99.37, 1.2.98.1	-	C	ko:K00048,ko:K17067	ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
MHAKHEAG_00682	4.46e-100	-	-	-	S	-	-	-	Domain of unknown function (DUF4190)
MHAKHEAG_00683	4.62e-254	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MHAKHEAG_00684	2.24e-194	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MHAKHEAG_00686	6.43e-16	-	-	-	-	-	-	-	-
MHAKHEAG_00687	3.18e-30	-	-	-	-	-	-	-	-
MHAKHEAG_00688	3.68e-296	-	-	-	S	-	-	-	Helix-turn-helix domain
MHAKHEAG_00689	4.34e-126	-	-	-	S	ko:K18955	-	ko00000,ko03000	Transcription factor WhiB
MHAKHEAG_00690	2.08e-133	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	AAA domain
MHAKHEAG_00691	1.43e-47	-	-	-	-	-	-	-	-
MHAKHEAG_00692	1.03e-91	-	-	-	-	-	-	-	-
MHAKHEAG_00693	3.5e-36	-	-	-	-	-	-	-	-
MHAKHEAG_00694	6.52e-157	-	-	-	K	-	-	-	Helix-turn-helix domain protein
MHAKHEAG_00696	0.0	-	-	-	M	-	-	-	Cell surface antigen C-terminus
MHAKHEAG_00697	2.3e-56	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	PFAM ABC-2 type transporter
MHAKHEAG_00698	4.07e-50	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPase activity
MHAKHEAG_00701	2.76e-104	-	-	-	-	-	-	-	-
MHAKHEAG_00702	3.3e-138	-	-	-	-	-	-	-	-
MHAKHEAG_00703	8.73e-154	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MHAKHEAG_00704	1.98e-125	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
MHAKHEAG_00705	4.57e-248	-	-	-	-	-	-	-	-
MHAKHEAG_00706	6.87e-172	-	-	-	V	-	-	-	ABC transporter
MHAKHEAG_00707	1.35e-239	-	-	-	V	-	-	-	Putative peptidoglycan binding domain
MHAKHEAG_00708	2.29e-154	-	-	-	-	-	-	-	-
MHAKHEAG_00709	1.03e-77	-	-	-	-	-	-	-	-
MHAKHEAG_00710	1.02e-153	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
MHAKHEAG_00711	1.1e-296	-	2.7.13.3	-	T	ko:K18351	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	GHKL domain
MHAKHEAG_00712	1e-125	-	-	-	K	-	-	-	transcriptional regulator
MHAKHEAG_00713	1.78e-57	-	-	-	-	-	-	-	-
MHAKHEAG_00714	1.44e-42	-	-	-	-	-	-	-	-
MHAKHEAG_00715	2.17e-183	-	-	-	-	-	-	-	-
MHAKHEAG_00716	7.5e-83	-	-	-	S	-	-	-	PrgI family protein
MHAKHEAG_00717	0.0	-	-	-	U	-	-	-	type IV secretory pathway VirB4
MHAKHEAG_00718	3.71e-265	-	-	-	M	-	-	-	CHAP domain
MHAKHEAG_00719	4.29e-91	-	-	-	-	-	-	-	-
MHAKHEAG_00720	2.16e-117	-	-	-	-	-	-	-	-
MHAKHEAG_00721	1.12e-74	-	-	-	-	-	-	-	-
MHAKHEAG_00724	1.1e-155	-	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
MHAKHEAG_00727	0.0	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	Type IV secretory system Conjugative DNA transfer
MHAKHEAG_00728	7.01e-83	-	-	-	-	-	-	-	-
MHAKHEAG_00729	5.65e-60	-	-	-	-	-	-	-	-
MHAKHEAG_00730	6.3e-161	-	-	-	-	-	-	-	-
MHAKHEAG_00731	1.33e-312	-	-	-	S	-	-	-	Antirestriction protein (ArdA)
MHAKHEAG_00732	5.98e-169	-	-	-	-	-	-	-	-
MHAKHEAG_00733	2.79e-184	-	-	-	S	-	-	-	Protein of unknown function (DUF3801)
MHAKHEAG_00734	1.89e-311	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
MHAKHEAG_00735	1.08e-88	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
MHAKHEAG_00736	1.96e-96	-	-	-	-	-	-	-	-
MHAKHEAG_00737	6.28e-54	-	-	-	-	-	-	-	-
MHAKHEAG_00738	4.13e-308	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	ParB-like nuclease domain
MHAKHEAG_00739	3.49e-126	-	-	-	S	-	-	-	Domain of unknown function (DUF4192)
MHAKHEAG_00740	2.09e-205	-	-	-	T	-	-	-	Histidine kinase
MHAKHEAG_00741	8.98e-139	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MHAKHEAG_00742	4.92e-89	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MHAKHEAG_00743	2.01e-20	-	-	-	-	-	-	-	-
MHAKHEAG_00744	8.1e-220	-	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MHAKHEAG_00745	5.42e-41	-	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MHAKHEAG_00746	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
MHAKHEAG_00747	1.22e-100	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MHAKHEAG_00748	2.4e-91	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MHAKHEAG_00749	1.12e-60	-	-	-	T	-	-	-	Histidine kinase
MHAKHEAG_00750	1.16e-95	-	-	-	K	-	-	-	Bacterial regulatory proteins, luxR family
MHAKHEAG_00751	1.38e-96	-	-	-	KLT	-	-	-	serine threonine protein kinase
MHAKHEAG_00753	2.68e-35	ptrB	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Protease II
MHAKHEAG_00754	3.37e-90	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
MHAKHEAG_00755	8.68e-293	intA	-	-	L	-	-	-	Phage integrase family
MHAKHEAG_00756	1.27e-10	intA	-	-	L	-	-	-	Phage integrase family
MHAKHEAG_00759	1.66e-283	intA	-	-	L	-	-	-	Phage integrase family
MHAKHEAG_00760	1.31e-108	-	-	-	-	-	-	-	-
MHAKHEAG_00761	9.25e-27	-	-	-	S	-	-	-	Helix-turn-helix domain
MHAKHEAG_00762	7.77e-24	-	-	-	S	ko:K18955	-	ko00000,ko03000	Transcription factor WhiB
MHAKHEAG_00763	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
MHAKHEAG_00764	0.0	lacZ6	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
MHAKHEAG_00765	5.98e-111	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
MHAKHEAG_00766	1.38e-228	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
MHAKHEAG_00767	1.35e-299	-	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MHAKHEAG_00768	5.05e-153	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
MHAKHEAG_00770	3.34e-131	-	-	-	-	-	-	-	-
MHAKHEAG_00771	6.51e-234	-	-	-	V	-	-	-	N-Acetylmuramoyl-L-alanine amidase
MHAKHEAG_00772	1.11e-138	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MHAKHEAG_00773	4.81e-236	-	-	-	-	-	-	-	-
MHAKHEAG_00774	2.57e-14	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
MHAKHEAG_00775	1.25e-288	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MHAKHEAG_00776	7.89e-270	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
MHAKHEAG_00777	3.41e-143	vex	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MHAKHEAG_00778	1.55e-66	-	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
MHAKHEAG_00779	1.04e-248	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MHAKHEAG_00780	2e-125	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	low molecular weight
MHAKHEAG_00781	5.46e-165	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dihydrofolate reductase
MHAKHEAG_00782	4.99e-223	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MHAKHEAG_00783	1.52e-94	-	-	-	O	-	-	-	OsmC-like protein
MHAKHEAG_00784	1.31e-244	-	-	-	T	-	-	-	Universal stress protein family
MHAKHEAG_00785	9.72e-153	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
MHAKHEAG_00786	1.05e-231	-	-	-	S	-	-	-	CHAP domain
MHAKHEAG_00787	2e-274	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MHAKHEAG_00788	4.6e-53	-	-	-	-	-	-	-	-
MHAKHEAG_00789	3.76e-287	senX3	2.7.13.3	-	T	ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
MHAKHEAG_00790	9.33e-153	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
MHAKHEAG_00791	2.85e-13	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MHAKHEAG_00792	3.69e-178	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MHAKHEAG_00793	2.37e-223	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
MHAKHEAG_00794	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
MHAKHEAG_00796	3.69e-278	-	-	-	EGP	ko:K08156,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
MHAKHEAG_00797	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4037)
MHAKHEAG_00798	2.25e-144	-	-	-	S	-	-	-	Protein of unknown function (DUF4125)
MHAKHEAG_00799	2.71e-195	-	-	-	-	-	-	-	-
MHAKHEAG_00800	0.0	pspC	-	-	KT	-	-	-	PspC domain
MHAKHEAG_00801	0.0	tcsS3	-	-	KT	-	-	-	PspC domain
MHAKHEAG_00802	5.87e-163	tcsR3	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MHAKHEAG_00803	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MHAKHEAG_00804	5.83e-181	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
MHAKHEAG_00805	4.36e-239	opcA	-	-	G	-	-	-	Glucose-6-phosphate dehydrogenase subunit
MHAKHEAG_00806	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MHAKHEAG_00807	2.95e-121	-	-	-	-	-	-	-	-
MHAKHEAG_00809	0.0	-	3.2.1.50	-	G	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
MHAKHEAG_00811	1.21e-302	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MHAKHEAG_00812	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
MHAKHEAG_00813	1.12e-270	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
MHAKHEAG_00814	2.93e-197	arbG	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
MHAKHEAG_00815	0.0	ptsG	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system, glucose-specific IIABC component
MHAKHEAG_00817	1.74e-95	-	-	-	M	-	-	-	Spy0128-like isopeptide containing domain
MHAKHEAG_00819	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
MHAKHEAG_00820	0.0	merA	1.16.1.1	-	C	ko:K00520,ko:K21739	-	ko00000,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MHAKHEAG_00821	0.0	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylglucosaminidase
MHAKHEAG_00822	2.41e-258	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHAKHEAG_00823	7.42e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MHAKHEAG_00824	5.18e-07	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
MHAKHEAG_00825	1.63e-140	-	-	-	-	-	-	-	-
MHAKHEAG_00826	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MHAKHEAG_00827	6.67e-300	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin kinase
MHAKHEAG_00828	2.35e-290	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MHAKHEAG_00829	1.77e-123	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MHAKHEAG_00830	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MHAKHEAG_00831	8.14e-242	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MHAKHEAG_00832	4.96e-222	-	-	-	-	-	-	-	-
MHAKHEAG_00833	3.08e-110	tnp3503b	-	-	L	-	-	-	Transposase and inactivated derivatives
MHAKHEAG_00835	5.51e-199	-	-	-	E	-	-	-	Transglutaminase/protease-like homologues
MHAKHEAG_00836	0.0	gcs2	-	-	S	ko:K06048	-	ko00000,ko01000	A circularly permuted ATPgrasp
MHAKHEAG_00837	2.01e-219	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MHAKHEAG_00838	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	hydrolase family 20, catalytic
MHAKHEAG_00839	3.77e-95	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MHAKHEAG_00840	1.4e-236	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHAKHEAG_00841	7.34e-86	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MHAKHEAG_00842	2.84e-82	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MHAKHEAG_00843	1.03e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MHAKHEAG_00844	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MHAKHEAG_00845	4.79e-129	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MHAKHEAG_00846	0.0	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MHAKHEAG_00847	1.51e-94	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
MHAKHEAG_00848	1.46e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30p/L7e
MHAKHEAG_00849	5.38e-147	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MHAKHEAG_00850	1.53e-76	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MHAKHEAG_00851	2.69e-122	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MHAKHEAG_00852	9.65e-91	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MHAKHEAG_00853	7.06e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MHAKHEAG_00854	1.6e-133	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MHAKHEAG_00855	9.32e-70	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MHAKHEAG_00856	7.32e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MHAKHEAG_00857	9.4e-57	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MHAKHEAG_00858	6.77e-51	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MHAKHEAG_00859	2.71e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MHAKHEAG_00860	5.27e-159	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MHAKHEAG_00861	2.21e-74	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MHAKHEAG_00862	1.4e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MHAKHEAG_00863	1.15e-196	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MHAKHEAG_00864	2.54e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MHAKHEAG_00865	1.34e-154	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MHAKHEAG_00866	6.65e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MHAKHEAG_00867	5.42e-67	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MHAKHEAG_00868	8.68e-24	-	-	-	S	-	-	-	YwiC-like protein
MHAKHEAG_00869	1.36e-213	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
MHAKHEAG_00870	0.0	adhE	1.1.1.1, 1.2.1.10, 1.2.1.81	-	C	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
MHAKHEAG_00871	2.39e-295	-	-	-	GK	-	-	-	transcriptional repressor of nag (N-acetylglucosamine) operon K02565
MHAKHEAG_00872	0.0	glgX	3.2.1.196, 3.2.1.68	CBM48,GH13	G	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
MHAKHEAG_00873	1.71e-99	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MHAKHEAG_00874	2.64e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MHAKHEAG_00875	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
MHAKHEAG_00876	7.22e-153	-	-	-	-	-	-	-	-
MHAKHEAG_00877	1.63e-146	yigZ	-	-	S	-	-	-	Uncharacterized protein family UPF0029
MHAKHEAG_00878	0.0	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
MHAKHEAG_00880	1.74e-302	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MHAKHEAG_00881	5.74e-285	dapC	-	-	E	-	-	-	Aminotransferase class I and II
MHAKHEAG_00882	3.55e-81	fdxA	-	-	C	ko:K05524	-	ko00000	4Fe-4S binding domain
MHAKHEAG_00883	4.5e-279	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
MHAKHEAG_00884	2.71e-35	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
MHAKHEAG_00888	3.93e-74	-	-	-	KLT	-	-	-	Associated with various cellular activities
MHAKHEAG_00889	2.01e-165	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
MHAKHEAG_00890	3.49e-63	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MHAKHEAG_00891	7.19e-256	-	-	-	-	-	-	-	-
MHAKHEAG_00892	9.98e-121	rimJ	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MHAKHEAG_00893	5.69e-154	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
MHAKHEAG_00894	1.88e-51	-	-	-	S	-	-	-	Putative regulatory protein
MHAKHEAG_00895	2.1e-141	-	-	-	NO	-	-	-	SAF
MHAKHEAG_00896	1.66e-55	-	-	-	-	-	-	-	-
MHAKHEAG_00897	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
MHAKHEAG_00898	0.0	-	-	-	T	-	-	-	Forkhead associated domain
MHAKHEAG_00900	5.13e-61	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MHAKHEAG_00901	5.06e-115	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MHAKHEAG_00902	5.87e-229	xynB2	1.1.1.169	-	E	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	lipolytic protein G-D-S-L family
MHAKHEAG_00903	0.0	-	-	-	G	-	-	-	BNR repeat-like domain
MHAKHEAG_00905	5.92e-313	-	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
MHAKHEAG_00907	1.74e-217	-	-	-	S	-	-	-	Protein conserved in bacteria
MHAKHEAG_00908	1.29e-189	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MHAKHEAG_00909	7.7e-233	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
MHAKHEAG_00910	8.51e-219	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MHAKHEAG_00911	1.71e-262	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import
MHAKHEAG_00912	5.44e-165	regX3	-	-	KT	ko:K07776	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
MHAKHEAG_00913	8.66e-310	phoR	2.7.13.3	-	T	ko:K07636,ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
MHAKHEAG_00914	2.57e-159	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MHAKHEAG_00915	0.0	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MHAKHEAG_00916	2.07e-141	-	-	-	-	-	-	-	-
MHAKHEAG_00917	1.83e-244	cbs	2.5.1.47, 4.2.1.22	-	E	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
MHAKHEAG_00918	4.33e-281	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
MHAKHEAG_00919	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
MHAKHEAG_00920	1.27e-118	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MHAKHEAG_00921	4.1e-39	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MHAKHEAG_00922	2.63e-121	cysE	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MHAKHEAG_00923	0.0	aap1	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
MHAKHEAG_00924	0.0	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MHAKHEAG_00925	1.45e-312	dgt	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
MHAKHEAG_00926	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MHAKHEAG_00927	3.19e-205	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
MHAKHEAG_00928	2.99e-289	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
MHAKHEAG_00929	2.12e-59	-	-	-	S	ko:K06990	-	ko00000,ko04812	Memo-like protein
MHAKHEAG_00931	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MHAKHEAG_00932	5.85e-228	yogA	-	-	C	-	-	-	Zinc-binding dehydrogenase
MHAKHEAG_00933	5.14e-111	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MHAKHEAG_00934	5.14e-291	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MHAKHEAG_00935	8.27e-96	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
MHAKHEAG_00936	5.38e-61	-	-	-	-	-	-	-	-
MHAKHEAG_00937	9.36e-66	-	-	-	S	-	-	-	TIGRFAM TIGR03943 family protein
MHAKHEAG_00938	1.7e-84	-	-	-	S	-	-	-	TIGRFAM TIGR03943 family protein
MHAKHEAG_00939	2.92e-257	-	-	-	S	ko:K07089	-	ko00000	Predicted permease
MHAKHEAG_00940	6.34e-33	-	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal L32p protein family
MHAKHEAG_00941	3.05e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L36
MHAKHEAG_00942	1.79e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
MHAKHEAG_00943	4.85e-65	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MHAKHEAG_00944	4.39e-62	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
MHAKHEAG_00945	1.82e-178	-	-	-	S	-	-	-	cobalamin synthesis protein
MHAKHEAG_00946	5.31e-210	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
MHAKHEAG_00947	0.0	lysX	-	-	S	-	-	-	Uncharacterised conserved protein (DUF2156)
MHAKHEAG_00948	0.0	-	-	-	S	-	-	-	Putative esterase
MHAKHEAG_00949	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
MHAKHEAG_00950	5.35e-307	purD	6.3.3.1, 6.3.4.13	-	F	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
MHAKHEAG_00951	1.21e-244	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
MHAKHEAG_00952	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MHAKHEAG_00953	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	DNA-damage repair protein (DNA polymerase IV) K00961
MHAKHEAG_00954	9.82e-45	-	-	-	-	-	-	-	-
MHAKHEAG_00955	1.64e-90	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHAKHEAG_00956	4.51e-44	-	-	-	K	-	-	-	DNA-binding transcription factor activity
MHAKHEAG_00957	3.14e-188	nnrE	-	-	L	-	-	-	Uracil DNA glycosylase superfamily
MHAKHEAG_00958	2.2e-140	-	-	-	S	-	-	-	Protein of unknown function (DUF4230)
MHAKHEAG_00959	5.92e-142	-	-	-	-	-	-	-	-
MHAKHEAG_00960	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
MHAKHEAG_00961	2.05e-177	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
MHAKHEAG_00962	1.91e-298	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MHAKHEAG_00963	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
MHAKHEAG_00964	4.41e-291	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
MHAKHEAG_00965	5.42e-255	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
MHAKHEAG_00967	5.77e-81	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MHAKHEAG_00968	9.4e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MHAKHEAG_00969	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MHAKHEAG_00970	5.83e-293	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MHAKHEAG_00971	0.0	-	-	-	S	-	-	-	Esterase-like activity of phytase
MHAKHEAG_00972	1.68e-251	-	-	-	EGP	-	-	-	Transmembrane secretion effector
MHAKHEAG_00974	3.8e-135	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MHAKHEAG_00975	2.04e-150	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MHAKHEAG_00976	9.86e-304	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
MHAKHEAG_00977	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
MHAKHEAG_00978	0.0	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MHAKHEAG_00979	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
MHAKHEAG_00980	6.09e-152	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MHAKHEAG_00981	0.0	-	-	-	T	-	-	-	Histidine kinase
MHAKHEAG_00982	2.17e-151	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
MHAKHEAG_00983	8.71e-176	-	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MHAKHEAG_00984	1.83e-217	-	-	-	EG	-	-	-	EamA-like transporter family
MHAKHEAG_00985	1.42e-156	ywaC	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
MHAKHEAG_00986	0.0	miaB	2.8.4.3	-	H	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MHAKHEAG_00987	2.09e-234	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MHAKHEAG_00988	3.82e-176	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
MHAKHEAG_00989	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE family protein
MHAKHEAG_00990	6.37e-160	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MHAKHEAG_00991	1.14e-124	cinA	3.5.1.42	-	S	ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
MHAKHEAG_00992	2.53e-106	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MHAKHEAG_00993	1.96e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF3046)
MHAKHEAG_00994	7.71e-276	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MHAKHEAG_00995	1.39e-95	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
MHAKHEAG_00997	3.68e-152	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MHAKHEAG_00998	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MHAKHEAG_00999	1.86e-245	trpD	2.4.2.18	-	F	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MHAKHEAG_01000	3.08e-140	-	-	-	-	-	-	-	-
MHAKHEAG_01001	3.55e-172	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
MHAKHEAG_01002	0.0	pknL	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	PASTA
MHAKHEAG_01003	2.13e-255	idsA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MHAKHEAG_01004	1.98e-157	-	-	-	-	-	-	-	-
MHAKHEAG_01005	3.09e-252	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MHAKHEAG_01006	0.0	gyrB2	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
MHAKHEAG_01007	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
MHAKHEAG_01009	2.83e-22	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
MHAKHEAG_01010	1.65e-34	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
MHAKHEAG_01011	0.0	lhr	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
MHAKHEAG_01012	0.0	gyrA2	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
MHAKHEAG_01013	3.3e-300	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
MHAKHEAG_01014	7.18e-236	-	-	-	S	-	-	-	Protein of unknown function (DUF3071)
MHAKHEAG_01015	2.45e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4193)
MHAKHEAG_01016	5.02e-110	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
MHAKHEAG_01017	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MHAKHEAG_01018	2.33e-39	-	-	-	-	-	-	-	-
MHAKHEAG_01020	9.23e-266	-	-	-	E	-	-	-	Belongs to the peptidase S1B family
MHAKHEAG_01021	1.78e-89	-	-	-	T	-	-	-	Toxic component of a toxin-antitoxin (TA) module
MHAKHEAG_01022	9.55e-66	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MHAKHEAG_01023	3.42e-134	ppiA	5.2.1.8	-	G	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MHAKHEAG_01024	2.76e-212	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MHAKHEAG_01025	1.73e-107	-	-	-	P	-	-	-	ABC-type metal ion transport system permease component
MHAKHEAG_01026	2e-285	-	-	-	S	-	-	-	Peptidase dimerisation domain
MHAKHEAG_01027	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MHAKHEAG_01028	3.51e-52	-	-	-	-	-	-	-	-
MHAKHEAG_01029	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
MHAKHEAG_01030	3.65e-222	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MHAKHEAG_01031	1.94e-146	-	-	-	S	-	-	-	Protein of unknown function (DUF3000)
MHAKHEAG_01032	0.0	rnd	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
MHAKHEAG_01033	5.17e-307	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MHAKHEAG_01034	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
MHAKHEAG_01035	4.05e-147	clpP1	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MHAKHEAG_01036	9.32e-164	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MHAKHEAG_01037	1.23e-311	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MHAKHEAG_01040	4.28e-297	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
MHAKHEAG_01041	1.67e-290	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MHAKHEAG_01042	7.06e-221	fmt2	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
MHAKHEAG_01043	1.01e-150	safC	-	-	S	-	-	-	O-methyltransferase
MHAKHEAG_01044	3.57e-235	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
MHAKHEAG_01045	2.23e-93	yraN	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
MHAKHEAG_01046	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
MHAKHEAG_01047	0.0	dprA	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
MHAKHEAG_01048	0.0	sdhA	1.3.5.1, 1.3.5.4, 1.4.3.16	-	C	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Succinate dehydrogenase flavoprotein subunit
MHAKHEAG_01049	3.62e-212	pdxY	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
MHAKHEAG_01050	2.83e-201	-	-	-	S	-	-	-	Putative ABC-transporter type IV
MHAKHEAG_01051	0.0	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Aminotransferase class-V
MHAKHEAG_01052	1.63e-209	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MHAKHEAG_01053	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
MHAKHEAG_01054	0.0	-	-	-	I	-	-	-	PAP2 superfamily
MHAKHEAG_01055	4.15e-171	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MHAKHEAG_01056	0.0	-	-	-	T	-	-	-	Histidine kinase
MHAKHEAG_01057	0.0	pip	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	alpha/beta hydrolase fold
MHAKHEAG_01058	1.74e-182	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MHAKHEAG_01059	2.32e-210	iaaA	3.4.19.5	-	E	ko:K13051	-	ko00000,ko01000,ko01002	Asparaginase
MHAKHEAG_01060	1.28e-187	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
MHAKHEAG_01061	3.45e-240	acoA	1.2.4.1	-	C	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
MHAKHEAG_01062	1.1e-235	acoB	1.2.4.1, 1.2.4.4	-	C	ko:K00162,ko:K11381,ko:K21417	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
MHAKHEAG_01063	2.72e-261	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MHAKHEAG_01064	9.77e-123	-	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MHAKHEAG_01065	1.27e-292	-	2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83	-	E	ko:K00812,ko:K08969,ko:K10206,ko:K10907,ko:K14260,ko:K14261	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
MHAKHEAG_01066	1.02e-257	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MHAKHEAG_01067	1.44e-71	-	2.1.1.113, 2.1.1.72	-	L	ko:K00571,ko:K00590	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
MHAKHEAG_01068	3.61e-243	mod	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	PFAM DNA methylase
MHAKHEAG_01069	3.42e-298	-	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme res subunit
MHAKHEAG_01070	1.34e-75	-	-	-	J	-	-	-	tRNA cytidylyltransferase activity
MHAKHEAG_01071	1.3e-10	rep	3.6.4.12	-	L	ko:K03656,ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction
MHAKHEAG_01074	5.2e-63	-	-	-	-	-	-	-	-
MHAKHEAG_01075	8.04e-313	-	-	-	K	-	-	-	Fic/DOC family
MHAKHEAG_01076	2.73e-162	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
MHAKHEAG_01077	5.59e-78	yccF	-	-	S	-	-	-	Inner membrane component domain
MHAKHEAG_01078	3.83e-202	-	-	-	J	-	-	-	Methyltransferase domain
MHAKHEAG_01079	6.29e-103	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
MHAKHEAG_01080	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
MHAKHEAG_01081	6.04e-103	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MHAKHEAG_01083	1.1e-30	-	-	-	-	-	-	-	-
MHAKHEAG_01084	1.14e-261	-	-	-	S	-	-	-	Short C-terminal domain
MHAKHEAG_01085	1.1e-112	-	-	-	S	-	-	-	Helix-turn-helix
MHAKHEAG_01086	7.03e-86	-	-	-	S	-	-	-	Zincin-like metallopeptidase
MHAKHEAG_01088	1.66e-46	-	-	-	S	ko:K07069	-	ko00000	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
MHAKHEAG_01089	3.2e-48	-	-	-	-	-	-	-	-
MHAKHEAG_01090	1.5e-96	fms	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
MHAKHEAG_01091	2.14e-160	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
MHAKHEAG_01092	0.0	-	2.7.11.1	-	S	ko:K12132	-	ko00000,ko01000,ko01001	PASTA domain
MHAKHEAG_01094	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MHAKHEAG_01095	5.28e-152	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
MHAKHEAG_01096	8.63e-185	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
MHAKHEAG_01097	4.33e-238	-	-	-	S	-	-	-	Conserved hypothetical protein 698
MHAKHEAG_01098	1.72e-204	-	-	-	G	-	-	-	Phosphoglycerate mutase family
MHAKHEAG_01099	2.75e-304	rutG	-	-	F	ko:K02824,ko:K03458	-	ko00000,ko02000	Permease family
MHAKHEAG_01100	1.84e-98	-	-	-	K	-	-	-	AraC-like ligand binding domain
MHAKHEAG_01102	7.28e-71	-	-	-	IQ	-	-	-	oxidoreductase activity
MHAKHEAG_01103	9.25e-176	-	-	-	V	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
MHAKHEAG_01104	9.68e-173	-	-	-	V	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MHAKHEAG_01105	4.53e-205	tsnR	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHAKHEAG_01106	4.32e-259	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MHAKHEAG_01107	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Phenylalanyl-tRNA synthetase beta
MHAKHEAG_01108	1.23e-133	-	-	-	-	-	-	-	-
MHAKHEAG_01109	4.51e-261	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MHAKHEAG_01110	1.82e-275	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MHAKHEAG_01111	4.12e-227	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
MHAKHEAG_01112	4.83e-314	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
MHAKHEAG_01113	2.51e-234	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MHAKHEAG_01114	1.29e-112	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
MHAKHEAG_01115	5.96e-304	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
MHAKHEAG_01116	5.13e-61	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
MHAKHEAG_01117	2.11e-225	-	-	-	L	-	-	-	Phage integrase family
MHAKHEAG_01118	2e-41	-	-	-	-	-	-	-	-
MHAKHEAG_01119	2.59e-198	-	-	-	S	-	-	-	Domain of unknown function (DUF4357)
MHAKHEAG_01120	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	modification (methylase) protein of type I restriction-modification system K03427
MHAKHEAG_01121	3.19e-132	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
MHAKHEAG_01122	0.0	-	-	-	K	-	-	-	Putative DNA-binding domain
MHAKHEAG_01123	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
MHAKHEAG_01124	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
MHAKHEAG_01125	9.62e-142	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MHAKHEAG_01126	3.54e-185	-	-	-	S	-	-	-	Putative ABC-transporter type IV
MHAKHEAG_01127	0.0	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MHAKHEAG_01128	1.36e-267	-	-	-	L	-	-	-	Tetratricopeptide repeat
MHAKHEAG_01129	1.53e-242	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
MHAKHEAG_01131	9.34e-175	tlyA	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
MHAKHEAG_01132	1.03e-139	-	-	-	-	-	-	-	-
MHAKHEAG_01133	5.24e-150	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
MHAKHEAG_01134	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
MHAKHEAG_01135	3.15e-235	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MHAKHEAG_01136	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MHAKHEAG_01137	1.24e-158	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MHAKHEAG_01138	2.84e-77	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
MHAKHEAG_01139	2.47e-224	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MHAKHEAG_01140	6.5e-163	-	-	-	S	-	-	-	ABC-2 family transporter protein
MHAKHEAG_01141	3.24e-158	-	-	-	S	-	-	-	ABC-2 family transporter protein
MHAKHEAG_01142	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase N terminus
MHAKHEAG_01143	2.93e-299	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MHAKHEAG_01144	4.42e-121	-	-	-	-	-	-	-	-
MHAKHEAG_01145	5.93e-187	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MHAKHEAG_01146	2.54e-243	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MHAKHEAG_01148	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MHAKHEAG_01149	6.1e-89	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MHAKHEAG_01150	1.92e-176	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
MHAKHEAG_01151	2.55e-100	-	-	-	S	-	-	-	Bacterial PH domain
MHAKHEAG_01152	0.0	treS_1	-	-	G	-	-	-	Alpha amylase, catalytic domain
MHAKHEAG_01154	1.58e-158	-	-	-	-	-	-	-	-
MHAKHEAG_01155	2.32e-169	-	-	-	C	-	-	-	Putative TM nitroreductase
MHAKHEAG_01156	6.22e-188	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
MHAKHEAG_01157	3.34e-92	pdxH	-	-	S	ko:K07006	-	ko00000	Pfam:Pyridox_oxidase
MHAKHEAG_01158	1.06e-67	-	-	-	KT	-	-	-	RESPONSE REGULATOR receiver
MHAKHEAG_01159	5.57e-247	-	-	-	V	-	-	-	VanZ like family
MHAKHEAG_01160	5.99e-143	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MHAKHEAG_01161	2.67e-124	-	-	-	S	-	-	-	Putative ABC-transporter type IV
MHAKHEAG_01162	5.09e-203	-	-	-	-	-	-	-	-
MHAKHEAG_01164	3.33e-128	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
MHAKHEAG_01165	3.19e-38	-	-	-	EGP	ko:K03446,ko:K03466,ko:K03762,ko:K08217	-	br01600,ko00000,ko00002,ko01504,ko02000,ko03036	Major facilitator Superfamily
MHAKHEAG_01166	9.32e-225	-	-	-	M	-	-	-	heme binding
MHAKHEAG_01167	1.31e-103	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHAKHEAG_01169	1.72e-52	-	-	-	-	-	-	-	-
MHAKHEAG_01170	1.4e-170	-	-	-	S	-	-	-	SOS response associated peptidase (SRAP)
MHAKHEAG_01171	4.77e-97	qseC	2.7.13.3	-	T	ko:K02484,ko:K07637,ko:K07643,ko:K07645,ko:K07649,ko:K07653,ko:K18351	ko01502,ko01503,ko02020,ko02024,map01502,map01503,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	Histidine kinase
MHAKHEAG_01172	4.88e-236	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MHAKHEAG_01174	3.14e-117	-	-	-	F	-	-	-	Hydrolase of X-linked nucleoside diphosphate N terminal
MHAKHEAG_01175	6.31e-42	-	-	-	K	-	-	-	Transcriptional regulator
MHAKHEAG_01176	2.67e-117	-	-	-	K	-	-	-	FR47-like protein
MHAKHEAG_01177	1.3e-161	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MHAKHEAG_01178	9.61e-84	-	-	-	K	-	-	-	Protein of unknown function, DUF488
MHAKHEAG_01179	9.92e-206	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MHAKHEAG_01180	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MHAKHEAG_01181	9.92e-184	-	-	-	S	-	-	-	Domain of unknown function (DUF4194)
MHAKHEAG_01182	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MHAKHEAG_01183	0.0	-	-	-	E	-	-	-	Serine carboxypeptidase
MHAKHEAG_01184	1.72e-208	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
MHAKHEAG_01185	2.45e-218	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MHAKHEAG_01186	7.56e-214	-	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MHAKHEAG_01187	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MHAKHEAG_01188	2.02e-161	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
MHAKHEAG_01189	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
MHAKHEAG_01190	2.59e-232	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MHAKHEAG_01191	3.13e-153	tsaE	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
MHAKHEAG_01192	2.83e-203	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Glycoprotease family
MHAKHEAG_01193	7.03e-134	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	FR47-like protein
MHAKHEAG_01194	1.61e-250	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MHAKHEAG_01196	2.46e-167	-	-	-	M	-	-	-	Peptidase family M23
MHAKHEAG_01197	0.0	fadD1	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
MHAKHEAG_01198	0.0	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
MHAKHEAG_01199	1.35e-306	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
MHAKHEAG_01200	1.59e-255	guaB3	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase family protein
MHAKHEAG_01201	3.59e-118	-	-	-	-	-	-	-	-
MHAKHEAG_01202	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	long-chain-fatty acid CoA ligase
MHAKHEAG_01203	4.26e-113	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MHAKHEAG_01204	3.07e-188	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MHAKHEAG_01205	4.78e-188	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MHAKHEAG_01206	3.84e-165	-	-	-	S	-	-	-	alpha beta
MHAKHEAG_01207	6.31e-171	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MHAKHEAG_01208	6.26e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MHAKHEAG_01209	1.27e-226	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
MHAKHEAG_01210	1.48e-289	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MHAKHEAG_01211	1.82e-179	hisF	4.1.3.27	-	E	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MHAKHEAG_01212	4.17e-97	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MHAKHEAG_01213	0.0	trpE	4.1.3.27	-	E	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MHAKHEAG_01214	6.09e-311	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MHAKHEAG_01215	3.93e-223	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MHAKHEAG_01216	5.52e-215	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
MHAKHEAG_01218	2.45e-61	-	-	-	-	-	-	-	-
MHAKHEAG_01219	9.16e-182	nfrA	-	-	C	-	-	-	Nitroreductase family
MHAKHEAG_01220	5.82e-89	-	-	-	S	-	-	-	Protein of unknown function (DUF4235)
MHAKHEAG_01221	3.05e-179	gpm2	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
MHAKHEAG_01223	2.63e-241	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MHAKHEAG_01224	0.0	strK	3.1.3.1, 3.1.3.39	-	P	ko:K01077,ko:K04342	ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
MHAKHEAG_01225	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MHAKHEAG_01226	8.46e-88	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MHAKHEAG_01227	1.35e-236	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	DnaJ molecular chaperone homology domain
MHAKHEAG_01228	6.42e-112	hspR	-	-	K	ko:K13640	-	ko00000,ko03000	transcriptional regulator, MerR family
MHAKHEAG_01229	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR repeat-like domain
MHAKHEAG_01230	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR Asp-box repeat
MHAKHEAG_01231	1.17e-171	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
MHAKHEAG_01233	2.18e-162	dedA1	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
MHAKHEAG_01234	5.14e-219	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MHAKHEAG_01235	1.6e-83	-	-	-	-	-	-	-	-
MHAKHEAG_01236	7.68e-170	-	-	-	-	-	-	-	-
MHAKHEAG_01237	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MHAKHEAG_01238	1.2e-107	-	-	-	K	-	-	-	Transcriptional regulator
MHAKHEAG_01240	0.0	-	-	-	G	ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
MHAKHEAG_01241	5.27e-235	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
MHAKHEAG_01242	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
MHAKHEAG_01244	3.34e-211	-	-	-	S	-	-	-	Glutamine amidotransferase domain
MHAKHEAG_01245	3.28e-176	-	-	-	T	ko:K06950	-	ko00000	HD domain
MHAKHEAG_01246	3.15e-259	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MHAKHEAG_01247	0.0	-	-	-	V	-	-	-	ABC transporter permease
MHAKHEAG_01248	0.0	-	-	-	H	-	-	-	Protein of unknown function (DUF4012)
MHAKHEAG_01249	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MHAKHEAG_01250	5.53e-211	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MHAKHEAG_01251	1.99e-36	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	ThiS family
MHAKHEAG_01252	0.0	-	-	-	-	-	-	-	-
MHAKHEAG_01253	7.47e-267	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
MHAKHEAG_01254	9.1e-39	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MHAKHEAG_01255	2.88e-25	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
MHAKHEAG_01256	8.69e-129	-	-	-	-	-	-	-	-
MHAKHEAG_01257	1.1e-282	mutT	3.6.1.55	-	LT	ko:K03574	-	ko00000,ko01000,ko03400	Phosphoglycerate mutase family
MHAKHEAG_01258	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MHAKHEAG_01260	1.34e-196	-	-	-	D	-	-	-	bacterial-type flagellum organization
MHAKHEAG_01261	6.74e-244	cpaF	-	-	U	ko:K02283	-	ko00000,ko02035,ko02044	Type II IV secretion system protein
MHAKHEAG_01262	2.62e-157	-	-	-	U	ko:K12510	-	ko00000,ko02044	Type ii secretion system
MHAKHEAG_01264	1.3e-20	-	-	-	NU	-	-	-	Type II secretion system (T2SS), protein F
MHAKHEAG_01265	3.96e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF4244)
MHAKHEAG_01266	1.04e-72	-	-	-	S	-	-	-	TIGRFAM helicase secretion neighborhood TadE-like protein
MHAKHEAG_01267	1.61e-274	-	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Diacylglycerol kinase catalytic domain protein
MHAKHEAG_01268	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III subunit gamma tau
MHAKHEAG_01269	1.21e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MHAKHEAG_01270	2.29e-176	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
MHAKHEAG_01271	1.42e-126	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
MHAKHEAG_01273	7.91e-271	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MHAKHEAG_01274	1.77e-148	-	-	-	-	-	-	-	-
MHAKHEAG_01275	0.0	-	2.7.11.1	-	S	ko:K12132	-	ko00000,ko01000,ko01001	PASTA domain
MHAKHEAG_01276	3.11e-19	-	2.7.11.1	-	S	ko:K12132	-	ko00000,ko01000,ko01001	PASTA domain
MHAKHEAG_01277	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MHAKHEAG_01278	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MHAKHEAG_01279	0.0	pbp5	-	-	M	-	-	-	Transglycosylase
MHAKHEAG_01280	1.8e-295	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
MHAKHEAG_01281	5.69e-176	-	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
MHAKHEAG_01282	0.0	-	-	-	M	-	-	-	PA domain
MHAKHEAG_01283	3.23e-251	-	-	-	I	-	-	-	PAP2 superfamily
MHAKHEAG_01284	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MHAKHEAG_01285	4.2e-158	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MHAKHEAG_01286	5.19e-273	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MHAKHEAG_01287	8.04e-257	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MHAKHEAG_01288	1.47e-50	hpr	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
MHAKHEAG_01289	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MHAKHEAG_01290	7.68e-62	-	-	-	S	-	-	-	Fic/DOC family
MHAKHEAG_01291	4.24e-49	-	-	-	S	-	-	-	Fic/DOC family
MHAKHEAG_01292	3.88e-250	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MHAKHEAG_01294	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	Iron permease FTR1 family
MHAKHEAG_01295	4.8e-150	-	-	-	P	ko:K07230	-	ko00000,ko02000	Fe2+ transport protein
MHAKHEAG_01296	8.34e-294	-	-	-	S	-	-	-	Predicted membrane protein (DUF2318)
MHAKHEAG_01297	2.54e-286	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MHAKHEAG_01298	9e-279	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MHAKHEAG_01299	2.6e-189	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MHAKHEAG_01300	8.08e-103	-	-	-	S	-	-	-	FMN_bind
MHAKHEAG_01301	1.5e-167	-	-	-	K	ko:K03489,ko:K03710	-	ko00000,ko03000	UTRA
MHAKHEAG_01302	1.13e-86	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MHAKHEAG_01303	0.0	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHAKHEAG_01304	5.95e-65	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MHAKHEAG_01305	2.92e-63	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
MHAKHEAG_01306	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
MHAKHEAG_01307	1.94e-38	-	-	-	Q	-	-	-	phosphatase activity
MHAKHEAG_01308	2.24e-103	-	-	-	-	-	-	-	-
MHAKHEAG_01309	2.65e-306	-	-	-	S	-	-	-	Putative ABC-transporter type IV
MHAKHEAG_01310	1.72e-209	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MHAKHEAG_01312	8.89e-111	-	-	-	E	-	-	-	IrrE N-terminal-like domain
MHAKHEAG_01313	9.77e-51	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
MHAKHEAG_01314	2.35e-156	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
MHAKHEAG_01316	9.34e-106	-	-	-	K	-	-	-	Winged helix DNA-binding domain
MHAKHEAG_01317	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MHAKHEAG_01318	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
MHAKHEAG_01319	6.48e-104	-	-	-	-	-	-	-	-
MHAKHEAG_01320	4.67e-68	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MHAKHEAG_01322	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
MHAKHEAG_01323	0.0	-	-	-	S	-	-	-	Glycosyl hydrolases related to GH101 family, GH129
MHAKHEAG_01324	6.85e-255	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyltransferase like family 2
MHAKHEAG_01325	1.36e-171	icaR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MHAKHEAG_01327	6.11e-277	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MHAKHEAG_01328	2.1e-305	amt	-	-	U	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
MHAKHEAG_01329	2.56e-72	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Nitrogen regulatory protein P-II
MHAKHEAG_01330	0.0	glnD	2.7.7.59	-	O	ko:K00990	ko02020,map02020	ko00000,ko00001,ko01000	Nucleotidyltransferase domain
MHAKHEAG_01331	0.0	dinF	-	-	V	-	-	-	MatE
MHAKHEAG_01332	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MHAKHEAG_01333	0.0	murE	-	-	M	-	-	-	Domain of unknown function (DUF1727)
MHAKHEAG_01334	1.02e-181	cobQ2	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
MHAKHEAG_01335	3.15e-44	-	-	-	S	-	-	-	granule-associated protein
MHAKHEAG_01336	0.0	-	-	-	S	ko:K03688	-	ko00000	ABC1 family
MHAKHEAG_01337	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
MHAKHEAG_01338	5.65e-57	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
MHAKHEAG_01339	2.51e-298	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
MHAKHEAG_01340	3.51e-164	pyrE1	-	-	F	-	-	-	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MHAKHEAG_01341	2.26e-212	trmH	2.1.1.34	-	J	ko:K00556	-	ko00000,ko01000,ko03016	RNA methyltransferase TrmH family
MHAKHEAG_01342	1.17e-75	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MHAKHEAG_01343	7.99e-73	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MHAKHEAG_01345	3.33e-64	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHAKHEAG_01346	0.0	gatA	6.3.5.6, 6.3.5.7	-	F	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MHAKHEAG_01347	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHAKHEAG_01348	1.96e-251	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MHAKHEAG_01349	6.51e-69	-	-	-	S	-	-	-	Protein of unknown function (DUF2469)
MHAKHEAG_01350	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
MHAKHEAG_01351	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MHAKHEAG_01352	8.37e-298	-	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K10907,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
MHAKHEAG_01353	1.56e-109	lrp_3	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	helix_turn_helix ASNC type
MHAKHEAG_01354	9.37e-96	tyrA	5.4.99.5	-	E	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
MHAKHEAG_01355	0.0	-	-	-	S	-	-	-	domain protein
MHAKHEAG_01356	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MHAKHEAG_01357	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
MHAKHEAG_01358	2.82e-160	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MHAKHEAG_01359	4.39e-172	glnR	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
MHAKHEAG_01360	5.6e-170	-	-	-	-	-	-	-	-
MHAKHEAG_01361	8.19e-134	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MHAKHEAG_01363	1.13e-118	ppa	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MHAKHEAG_01364	0.0	glgE	2.4.99.16	GH13	G	ko:K16147	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
MHAKHEAG_01365	0.0	-	-	-	K	-	-	-	RNA polymerase II activating transcription factor binding
MHAKHEAG_01366	8.85e-47	-	-	-	-	-	-	-	-
MHAKHEAG_01368	2.94e-265	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MHAKHEAG_01369	3.54e-188	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MHAKHEAG_01371	1.21e-40	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHAKHEAG_01372	7.5e-98	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MHAKHEAG_01373	8.04e-192	atpH	-	-	C	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHAKHEAG_01374	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MHAKHEAG_01375	2.73e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MHAKHEAG_01376	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MHAKHEAG_01377	1.39e-66	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MHAKHEAG_01378	1.06e-166	nucS	-	-	L	ko:K07503	-	ko00000,ko01000	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
MHAKHEAG_01379	8.27e-187	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
MHAKHEAG_01380	0.0	-	-	-	-	-	-	-	-
MHAKHEAG_01381	4.55e-194	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
MHAKHEAG_01382	2.14e-119	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
MHAKHEAG_01383	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase L chain, ATP binding domain protein
MHAKHEAG_01384	0.0	pccB	-	-	I	-	-	-	Carboxyl transferase domain
MHAKHEAG_01385	0.0	fas	-	-	I	ko:K11533	ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931	ko00000,ko00001,ko00002,ko01000,ko01004	Beta-ketoacyl synthase, C-terminal domain
MHAKHEAG_01386	6.8e-129	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MHAKHEAG_01387	1.64e-204	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
MHAKHEAG_01389	3.54e-167	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
MHAKHEAG_01391	1.77e-101	-	-	-	OU	-	-	-	Serine dehydrogenase proteinase
MHAKHEAG_01394	1.58e-75	-	-	-	-	-	-	-	-
MHAKHEAG_01395	3.76e-82	-	-	-	S	-	-	-	Bacterial PH domain
MHAKHEAG_01396	0.0	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylglucosaminidase
MHAKHEAG_01397	1.28e-154	-	-	-	-	-	-	-	-
MHAKHEAG_01398	8.32e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MHAKHEAG_01399	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MHAKHEAG_01400	1.16e-145	xylR	-	-	K	ko:K02529	-	ko00000,ko03000	purine nucleotide biosynthetic process
MHAKHEAG_01401	2.16e-122	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
MHAKHEAG_01402	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
MHAKHEAG_01403	5.25e-94	megL	4.4.1.11	-	E	ko:K01761	ko00270,ko00450,map00270,map00450	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
MHAKHEAG_01404	3.66e-241	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHAKHEAG_01405	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHAKHEAG_01406	1.36e-125	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
MHAKHEAG_01407	1.26e-55	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
MHAKHEAG_01408	2.79e-213	-	-	-	C	-	-	-	Oxidoreductase, aldo keto reductase family protein
MHAKHEAG_01409	5.31e-87	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
MHAKHEAG_01410	1.21e-58	tnp3521a2	-	-	L	-	-	-	Integrase core domain
MHAKHEAG_01411	5.58e-33	-	-	-	S	-	-	-	Adenine-specific methyltransferase EcoRI
MHAKHEAG_01412	9.3e-53	-	-	-	-	-	-	-	-
MHAKHEAG_01413	4.2e-145	pncA	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Isochorismatase family
MHAKHEAG_01415	2.02e-141	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MHAKHEAG_01416	1.25e-54	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MHAKHEAG_01418	1.67e-307	pbuX	-	-	F	ko:K03458	-	ko00000	Permease family
MHAKHEAG_01419	6.52e-139	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MHAKHEAG_01420	0.0	yrhL	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
MHAKHEAG_01421	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MHAKHEAG_01422	1e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4418)
MHAKHEAG_01423	9.28e-272	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MHAKHEAG_01424	1.29e-170	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MHAKHEAG_01425	1.83e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MHAKHEAG_01426	0.0	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
MHAKHEAG_01427	5.11e-172	-	5.4.2.12	-	G	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
MHAKHEAG_01428	4.03e-85	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
MHAKHEAG_01429	7.33e-50	-	-	-	-	-	-	-	-
MHAKHEAG_01430	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MHAKHEAG_01431	6.58e-99	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MHAKHEAG_01432	4.48e-247	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MHAKHEAG_01433	4.35e-68	-	3.4.23.43	-	S	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
MHAKHEAG_01434	4.5e-280	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MHAKHEAG_01435	0.0	aroB	2.7.1.71, 4.2.3.4	-	H	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MHAKHEAG_01436	1.6e-103	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
MHAKHEAG_01437	4.78e-138	-	-	-	-	-	-	-	-
MHAKHEAG_01438	3.46e-154	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MHAKHEAG_01439	1.76e-05	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase (surface protein transpeptidase)
MHAKHEAG_01440	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MHAKHEAG_01441	0.0	sufB	-	-	O	ko:K09014	-	ko00000	FeS assembly protein SufB
MHAKHEAG_01442	2.92e-298	sufD	-	-	O	ko:K09015	-	ko00000	FeS assembly protein SufD
MHAKHEAG_01443	2.13e-185	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
MHAKHEAG_01444	3.62e-306	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MHAKHEAG_01445	4.14e-132	iscU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
MHAKHEAG_01446	2.56e-141	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MHAKHEAG_01447	1.42e-308	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MHAKHEAG_01448	1.78e-208	spoU2	-	-	J	-	-	-	SpoU rRNA Methylase family
MHAKHEAG_01450	2.18e-175	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MHAKHEAG_01451	1.37e-76	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
MHAKHEAG_01452	1.49e-253	phoH	-	-	T	ko:K06217	-	ko00000	PhoH-like protein
MHAKHEAG_01453	1.82e-130	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MHAKHEAG_01454	0.0	corC	-	-	S	-	-	-	CBS domain
MHAKHEAG_01455	1.45e-236	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MHAKHEAG_01456	0.0	fadD2	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
MHAKHEAG_01457	5.66e-258	pntA	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	NAD(P) transhydrogenase subunit alpha part 1 K00324
MHAKHEAG_01458	1.08e-58	pntAB	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	4TM region of pyridine nucleotide transhydrogenase, mitoch
MHAKHEAG_01459	3.47e-306	pntB	1.6.1.2	-	C	ko:K00325	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MHAKHEAG_01460	4.21e-242	-	-	-	S	ko:K06889	-	ko00000	alpha beta
MHAKHEAG_01461	1.66e-128	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MHAKHEAG_01462	1.11e-287	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Amino-transferase class IV
MHAKHEAG_01464	3.19e-58	-	-	-	T	-	-	-	RNA ligase
MHAKHEAG_01465	2.68e-174	-	-	-	S	-	-	-	UPF0126 domain
MHAKHEAG_01466	3.91e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MHAKHEAG_01467	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MHAKHEAG_01468	3.85e-311	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
MHAKHEAG_01469	9.79e-18	-	-	-	S	ko:K07149	-	ko00000	Membrane
MHAKHEAG_01470	0.0	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K10907,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase, class I II
MHAKHEAG_01471	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
MHAKHEAG_01472	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase NADPH large subunit
MHAKHEAG_01473	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MHAKHEAG_01474	5.23e-107	-	-	-	-	-	-	-	-
MHAKHEAG_01475	5.58e-311	glgA	2.4.1.342	GT4	G	ko:K16148	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Starch synthase catalytic domain
MHAKHEAG_01476	4.56e-209	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MHAKHEAG_01477	2.18e-203	-	-	-	S	ko:K11206	-	ko00000,ko01000	Carbon-nitrogen hydrolase
MHAKHEAG_01478	4.78e-143	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
MHAKHEAG_01479	1.11e-239	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MHAKHEAG_01480	7.87e-51	-	-	-	L	-	-	-	Helix-turn-helix domain
MHAKHEAG_01481	2.81e-228	-	-	-	L	ko:K07485	-	ko00000	Transposase
MHAKHEAG_01482	1.09e-168	-	-	-	-	-	-	-	-
MHAKHEAG_01483	0.0	-	-	-	KL	-	-	-	Type III restriction enzyme res subunit
MHAKHEAG_01484	3.18e-49	-	-	-	L	-	-	-	Eco57I restriction-modification methylase
MHAKHEAG_01485	3.01e-71	-	-	-	L	-	-	-	Eco57I restriction-modification methylase
MHAKHEAG_01486	6.12e-233	-	-	-	V	-	-	-	Type III restriction enzyme res subunit
MHAKHEAG_01487	1.57e-67	-	-	-	S	-	-	-	SIR2-like domain
MHAKHEAG_01488	6.65e-317	-	-	-	S	ko:K06915	-	ko00000	AAA-like domain
MHAKHEAG_01489	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
MHAKHEAG_01490	7.96e-41	-	-	-	-	-	-	-	-
MHAKHEAG_01491	3.16e-118	-	-	-	E	-	-	-	Rard protein
MHAKHEAG_01492	1.17e-34	-	-	-	S	-	-	-	Rard protein
MHAKHEAG_01493	3.14e-225	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MHAKHEAG_01494	2e-265	trmI	2.1.1.219, 2.1.1.220	-	J	ko:K07442	-	ko00000,ko01000,ko03016	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MHAKHEAG_01495	1.67e-128	sixA	-	-	T	ko:K08296	-	ko00000,ko01000	Phosphoglycerate mutase family
MHAKHEAG_01496	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MHAKHEAG_01497	8.19e-209	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
MHAKHEAG_01499	0.0	glnE	2.7.7.42, 2.7.7.89	-	H	ko:K00982	-	ko00000,ko01000	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
MHAKHEAG_01500	2.71e-234	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MHAKHEAG_01501	1.83e-96	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
MHAKHEAG_01502	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MHAKHEAG_01503	3.99e-231	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
MHAKHEAG_01504	3.07e-201	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
MHAKHEAG_01505	1.01e-229	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MHAKHEAG_01506	5.01e-160	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MHAKHEAG_01507	9.04e-34	-	-	-	K	-	-	-	MerR family regulatory protein
MHAKHEAG_01508	1.09e-248	adh	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
MHAKHEAG_01509	6.71e-207	-	-	-	-	-	-	-	-
MHAKHEAG_01510	1.76e-19	-	-	-	KLT	-	-	-	Protein tyrosine kinase
MHAKHEAG_01511	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MHAKHEAG_01512	8.03e-311	-	-	-	V	-	-	-	MatE
MHAKHEAG_01513	6.88e-169	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
MHAKHEAG_01514	2.69e-172	-	-	-	L	ko:K07457	-	ko00000	endonuclease III
MHAKHEAG_01515	2.51e-120	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
MHAKHEAG_01516	3.24e-226	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MHAKHEAG_01517	2.58e-89	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin domain
MHAKHEAG_01518	3.44e-285	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	HipA N-terminal domain
MHAKHEAG_01519	1.17e-54	-	-	-	K	-	-	-	Helix-turn-helix
MHAKHEAG_01520	6.69e-61	tam	2.1.1.144, 2.1.1.197	-	FG	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	trans-aconitate 2-methyltransferase activity
MHAKHEAG_01521	9.14e-25	-	-	-	-	-	-	-	-
MHAKHEAG_01522	1.59e-129	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MHAKHEAG_01523	7.13e-35	-	-	-	T	-	-	-	Domain of unknown function (DUF4234)
MHAKHEAG_01524	7.12e-75	-	-	-	T	-	-	-	Domain of unknown function (DUF4234)
MHAKHEAG_01525	1.23e-221	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
MHAKHEAG_01526	6.72e-158	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MHAKHEAG_01527	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MHAKHEAG_01528	4.33e-185	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
MHAKHEAG_01529	5.71e-78	dkg	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
MHAKHEAG_01531	0.0	ugp	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MHAKHEAG_01532	0.0	-	-	-	K	-	-	-	WYL domain
MHAKHEAG_01533	1.29e-70	-	-	-	-	-	-	-	-
MHAKHEAG_01534	0.0	helY	-	-	L	ko:K03727	-	ko00000,ko01000	DEAD DEAH box helicase
MHAKHEAG_01535	1.11e-81	rbpA	-	-	K	-	-	-	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
MHAKHEAG_01536	5.93e-183	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
MHAKHEAG_01539	3.01e-117	-	-	-	K	-	-	-	Putative zinc ribbon domain
MHAKHEAG_01540	4.36e-162	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
MHAKHEAG_01541	4.2e-31	-	-	-	L	-	-	-	DNA integration
MHAKHEAG_01543	2.84e-82	-	-	-	-	-	-	-	-
MHAKHEAG_01544	5.64e-153	merR2	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MHAKHEAG_01545	2.88e-96	garA	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
MHAKHEAG_01546	2.65e-180	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
MHAKHEAG_01547	2.78e-57	sbp	-	-	S	-	-	-	Protein of unknown function (DUF1290)
MHAKHEAG_01548	5.59e-223	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
MHAKHEAG_01549	2.22e-151	pgsA2	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MHAKHEAG_01550	1.07e-200	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
MHAKHEAG_01551	1.2e-54	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-ATP pyrophosphohydrolase
MHAKHEAG_01552	8.92e-144	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3-epimerase
MHAKHEAG_01553	2.07e-237	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MHAKHEAG_01554	1.07e-208	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MHAKHEAG_01555	0.0	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MHAKHEAG_01556	0.0	der	-	-	F	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MHAKHEAG_01557	9.44e-187	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MHAKHEAG_01558	2.83e-166	-	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MHAKHEAG_01559	5.17e-56	-	-	-	-	-	-	-	-
MHAKHEAG_01560	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
MHAKHEAG_01561	1.1e-313	-	-	-	-	-	-	-	-
MHAKHEAG_01562	9.52e-212	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MHAKHEAG_01563	8.17e-285	sucC	6.2.1.5	-	F	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MHAKHEAG_01564	3.9e-131	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MHAKHEAG_01565	5.39e-65	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
MHAKHEAG_01566	8.06e-258	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MHAKHEAG_01567	3.69e-135	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MHAKHEAG_01569	2.64e-129	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MHAKHEAG_01570	2.79e-176	yebC	-	-	K	-	-	-	transcriptional regulatory protein
MHAKHEAG_01571	0.0	-	3.2.1.52	GH20	M	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
MHAKHEAG_01572	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MHAKHEAG_01573	0.0	-	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHAKHEAG_01576	0.0	-	-	-	-	-	-	-	-
MHAKHEAG_01580	2.89e-199	-	-	-	S	-	-	-	PAC2 family
MHAKHEAG_01581	8.18e-216	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MHAKHEAG_01582	8.17e-204	-	-	-	G	-	-	-	Fructosamine kinase
MHAKHEAG_01583	6.31e-273	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MHAKHEAG_01584	1.54e-274	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MHAKHEAG_01585	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
MHAKHEAG_01586	4.49e-258	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MHAKHEAG_01587	3.12e-182	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
MHAKHEAG_01588	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MHAKHEAG_01590	1.49e-308	-	-	-	V	-	-	-	MatE
MHAKHEAG_01591	2.44e-208	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MHAKHEAG_01592	1.18e-225	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
MHAKHEAG_01593	1.2e-45	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
MHAKHEAG_01594	3.84e-189	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MHAKHEAG_01595	6.71e-284	pgk	2.7.2.3, 5.3.1.1	-	F	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
MHAKHEAG_01596	3.23e-222	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MHAKHEAG_01597	3.02e-227	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MHAKHEAG_01598	2.6e-231	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate dehydrogenase substrate binding domain
MHAKHEAG_01599	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MHAKHEAG_01600	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MHAKHEAG_01601	2.59e-110	-	-	-	-	-	-	-	-
MHAKHEAG_01602	3.65e-08	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
MHAKHEAG_01603	5.01e-150	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
MHAKHEAG_01604	0.0	-	2.7.13.3	-	T	ko:K18351	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MHAKHEAG_01605	6.89e-180	-	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
MHAKHEAG_01606	0.0	ybiT	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
MHAKHEAG_01607	8.31e-254	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MHAKHEAG_01608	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MHAKHEAG_01609	1.41e-263	-	2.7.1.162	-	S	ko:K13059	-	ko00000,ko01000	Phosphotransferase enzyme family
MHAKHEAG_01610	3.68e-277	-	-	-	GK	-	-	-	ROK family
MHAKHEAG_01611	1.69e-228	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MHAKHEAG_01612	1.01e-198	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
MHAKHEAG_01613	2.88e-174	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
MHAKHEAG_01614	0.0	-	-	-	S	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
MHAKHEAG_01615	1.01e-65	-	-	-	-	-	-	-	-
MHAKHEAG_01616	3e-77	-	-	-	-	-	-	-	-
MHAKHEAG_01617	1.16e-120	-	-	-	J	-	-	-	tRNA 5'-leader removal
MHAKHEAG_01619	1.71e-155	-	-	-	S	-	-	-	CYTH
MHAKHEAG_01620	2.52e-214	ybbN	-	-	O	ko:K05838	-	ko00000,ko03110	Tetratricopeptide repeat
MHAKHEAG_01621	4.83e-231	-	-	-	-	-	-	-	-
MHAKHEAG_01622	2.08e-242	-	-	-	-	-	-	-	-
MHAKHEAG_01623	5.14e-222	-	5.2.1.8	-	M	ko:K01802	-	ko00000,ko01000	FKBP-type peptidyl-prolyl cis-trans isomerase
MHAKHEAG_01624	1.23e-159	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MHAKHEAG_01625	1.43e-95	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MHAKHEAG_01626	2.03e-185	-	-	-	-	-	-	-	-
MHAKHEAG_01627	9.78e-169	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MHAKHEAG_01628	1.05e-292	-	-	-	G	-	-	-	Transmembrane secretion effector
MHAKHEAG_01629	0.0	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MHAKHEAG_01630	5.26e-281	pyr	1.3.98.1	-	F	ko:K00226	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
MHAKHEAG_01631	1.74e-251	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MHAKHEAG_01633	0.0	-	-	-	KL	-	-	-	Psort location Cytoplasmic, score 8.87
MHAKHEAG_01634	3.31e-171	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MHAKHEAG_01635	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MHAKHEAG_01636	9.2e-179	ltbR	-	-	K	-	-	-	Transcriptional regulator, IclR family, C-terminal domain protein
MHAKHEAG_01637	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MHAKHEAG_01640	3.11e-84	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
MHAKHEAG_01641	2.92e-124	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
MHAKHEAG_01642	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MHAKHEAG_01644	2.24e-157	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
MHAKHEAG_01645	5.05e-258	-	-	-	P	-	-	-	NMT1/THI5 like
MHAKHEAG_01646	2.03e-178	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
MHAKHEAG_01647	9.77e-192	-	-	-	-	-	-	-	-
MHAKHEAG_01648	1.3e-160	-	-	-	G	-	-	-	Phosphoglycerate mutase family
MHAKHEAG_01649	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MHAKHEAG_01650	6.15e-127	-	-	-	S	-	-	-	GtrA-like protein
MHAKHEAG_01651	9.48e-83	-	-	-	S	-	-	-	Macrophage migration inhibitory factor (MIF)
MHAKHEAG_01652	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate-tetrahydrofolate ligase
MHAKHEAG_01653	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
MHAKHEAG_01654	3.03e-139	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
MHAKHEAG_01655	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
MHAKHEAG_01657	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
MHAKHEAG_01658	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MHAKHEAG_01659	7.47e-123	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MHAKHEAG_01660	3.12e-244	-	-	-	C	-	-	-	Aldo/keto reductase family
MHAKHEAG_01661	2.21e-41	-	-	-	M	-	-	-	F5/8 type C domain
MHAKHEAG_01662	3.89e-68	-	-	-	-	-	-	-	-
MHAKHEAG_01664	4.3e-144	-	-	-	Q	-	-	-	4'-phosphopantetheinyl transferase superfamily
MHAKHEAG_01665	1.11e-148	-	-	-	K	-	-	-	WHG domain
MHAKHEAG_01666	1.56e-37	-	-	-	IQ	-	-	-	[acyl-carrier-protein] S-malonyltransferase activity
MHAKHEAG_01667	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MHAKHEAG_01668	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
MHAKHEAG_01669	1.29e-191	-	-	-	L	ko:K07454	-	ko00000	HNH endonuclease
MHAKHEAG_01670	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
MHAKHEAG_01671	0.0	-	-	-	S	-	-	-	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MHAKHEAG_01673	8.41e-106	-	-	-	L	ko:K07485	-	ko00000	Transposase
MHAKHEAG_01674	7.13e-56	-	-	-	O	-	-	-	Glutaredoxin
MHAKHEAG_01675	5.34e-190	-	-	-	S	ko:K07058	-	ko00000	Virulence factor BrkB
MHAKHEAG_01676	1.38e-127	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Redoxin
MHAKHEAG_01677	2.48e-48	urtE	-	-	E	ko:K11963	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MHAKHEAG_01678	5.48e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MHAKHEAG_01679	2.21e-109	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MHAKHEAG_01680	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MHAKHEAG_01681	1.76e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MHAKHEAG_01682	7.06e-132	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
MHAKHEAG_01683	0.0	aroP	-	-	E	ko:K03293,ko:K11732	-	ko00000,ko02000	aromatic amino acid transport protein AroP K03293
MHAKHEAG_01684	0.0	lacZ	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
MHAKHEAG_01686	3.84e-233	-	-	-	S	-	-	-	Protein of unknown function (DUF559)
MHAKHEAG_01687	1.76e-260	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MHAKHEAG_01688	6.15e-261	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MHAKHEAG_01689	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
MHAKHEAG_01690	0.0	scrT	-	-	G	-	-	-	Transporter major facilitator family protein
MHAKHEAG_01691	5.41e-100	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Domain of unknown function (DUF1964)
MHAKHEAG_01692	1.81e-252	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MHAKHEAG_01693	3.43e-79	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHAKHEAG_01694	1.02e-209	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHAKHEAG_01695	1.94e-316	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MHAKHEAG_01696	1.25e-252	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
MHAKHEAG_01697	0.0	-	3.2.1.8, 3.5.1.104	-	G	ko:K01181,ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
MHAKHEAG_01699	3.57e-302	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
MHAKHEAG_01700	4.53e-45	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
MHAKHEAG_01701	7.68e-104	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
MHAKHEAG_01702	1.03e-53	-	-	-	S	-	-	-	Polyketide cyclase / dehydrase and lipid transport
MHAKHEAG_01703	6.31e-90	-	-	-	K	-	-	-	FR47-like protein
MHAKHEAG_01704	9.59e-104	-	-	-	S	-	-	-	Nucleotidyltransferase domain
MHAKHEAG_01705	2.08e-247	-	-	-	-	-	-	-	-
MHAKHEAG_01706	7.01e-98	-	-	-	S	-	-	-	Protein of unknown function DUF262
MHAKHEAG_01707	1.63e-63	-	-	-	S	-	-	-	Protein of unknown function DUF262
MHAKHEAG_01709	2.44e-216	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MHAKHEAG_01710	0.0	fprA	1.18.1.2, 1.19.1.1	-	C	ko:K00528	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase
MHAKHEAG_01711	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
MHAKHEAG_01712	0.0	degP	-	-	O	ko:K08372	ko02020,map02020	ko00000,ko00001,ko01000,ko01002	Domain present in PSD-95, Dlg, and ZO-1/2.
MHAKHEAG_01713	0.0	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MHAKHEAG_01715	4.51e-110	-	-	-	Q	-	-	-	Acetyltransferase (GNAT) domain
MHAKHEAG_01716	6.18e-199	-	-	-	I	-	-	-	Serine aminopeptidase, S33
MHAKHEAG_01717	3.02e-70	-	-	-	S	-	-	-	Putative heavy-metal-binding
MHAKHEAG_01718	3.91e-61	-	-	-	D	-	-	-	DivIVA domain protein
MHAKHEAG_01719	3.85e-115	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
MHAKHEAG_01720	0.0	-	-	-	KL	-	-	-	Domain of unknown function (DUF3427)
MHAKHEAG_01722	4.1e-251	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MHAKHEAG_01724	1.92e-146	-	-	-	-	-	-	-	-
MHAKHEAG_01725	1.94e-216	-	-	-	EG	-	-	-	EamA-like transporter family
MHAKHEAG_01726	7.23e-265	pldB	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Serine aminopeptidase, S33
MHAKHEAG_01727	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
MHAKHEAG_01728	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
MHAKHEAG_01729	0.0	pepX	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Dipeptidyl peptidase IV (DPP IV) N-terminal region
MHAKHEAG_01730	3.69e-167	fhaA	-	-	T	-	-	-	Protein of unknown function (DUF2662)
MHAKHEAG_01731	2.04e-122	fhaB	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
MHAKHEAG_01732	0.0	pstP	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
MHAKHEAG_01733	0.0	rodA	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MHAKHEAG_01734	0.0	pbpA	-	-	M	ko:K05364	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
MHAKHEAG_01735	5.69e-234	pknA	2.7.11.1	-	T	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
MHAKHEAG_01736	0.0	pknB	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
MHAKHEAG_01737	9.5e-156	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	para-aminobenzoate synthase glutamine amidotransferase component II
MHAKHEAG_01738	1.14e-295	srtB	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MHAKHEAG_01739	1.18e-182	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
MHAKHEAG_01740	8.05e-100	crgA	-	-	D	-	-	-	Involved in cell division
MHAKHEAG_01741	0.0	-	-	-	L	-	-	-	ribosomal rna small subunit methyltransferase
MHAKHEAG_01742	8.87e-118	-	-	-	L	-	-	-	HTH-like domain
MHAKHEAG_01743	2.4e-186	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
MHAKHEAG_01744	7.68e-47	-	-	-	-	-	-	-	-
MHAKHEAG_01745	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MHAKHEAG_01746	5.53e-96	-	-	-	I	-	-	-	Sterol carrier protein
MHAKHEAG_01747	1.55e-42	-	-	-	V	ko:K06147	-	ko00000,ko02000	ATPases associated with a variety of cellular activities
MHAKHEAG_01748	1.48e-58	-	-	-	L	ko:K07485	-	ko00000	Transposase
MHAKHEAG_01749	2.24e-58	istB	-	-	L	-	-	-	IstB-like ATP binding protein
MHAKHEAG_01750	7.04e-57	-	-	-	L	-	-	-	Integrase core domain
MHAKHEAG_01751	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
MHAKHEAG_01752	1.9e-17	-	-	-	-	-	-	-	-
MHAKHEAG_01753	2.66e-76	yccF	-	-	S	-	-	-	Inner membrane component domain
MHAKHEAG_01754	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
MHAKHEAG_01755	4.77e-104	tnp3521a2	-	-	L	-	-	-	Integrase core domain
MHAKHEAG_01756	7.63e-228	-	-	-	S	-	-	-	Amidohydrolase family
MHAKHEAG_01757	0.0	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
MHAKHEAG_01758	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MHAKHEAG_01759	1.95e-308	-	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
MHAKHEAG_01760	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
MHAKHEAG_01761	1.01e-137	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
MHAKHEAG_01762	6.08e-154	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
MHAKHEAG_01763	2.1e-67	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MHAKHEAG_01764	3.36e-306	-	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
MHAKHEAG_01765	9.86e-241	-	-	-	EG	-	-	-	EamA-like transporter family
MHAKHEAG_01766	2.68e-110	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MHAKHEAG_01767	2.08e-175	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
MHAKHEAG_01768	0.0	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
MHAKHEAG_01769	1.49e-54	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MHAKHEAG_01770	1.03e-100	ulaC	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHAKHEAG_01771	4.91e-242	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MHAKHEAG_01772	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
MHAKHEAG_01775	0.0	-	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	arabinose metabolic process
MHAKHEAG_01776	9.15e-79	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MHAKHEAG_01777	3e-158	gntR	-	-	K	-	-	-	FCD
MHAKHEAG_01778	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MHAKHEAG_01782	8.24e-21	-	-	-	K	-	-	-	Helix-turn-helix domain
MHAKHEAG_01783	2.73e-19	-	-	-	S	-	-	-	Domain of unknown function (DUF4160)
MHAKHEAG_01784	2.87e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF2442)
MHAKHEAG_01785	9.05e-12	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MHAKHEAG_01786	4.38e-289	-	-	-	I	-	-	-	Serine aminopeptidase, S33
MHAKHEAG_01787	4.42e-238	-	-	-	K	-	-	-	Periplasmic binding protein domain
MHAKHEAG_01788	4.34e-240	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
MHAKHEAG_01790	1.44e-104	-	-	-	S	-	-	-	Transmembrane domain of unknown function (DUF3566)
MHAKHEAG_01791	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHAKHEAG_01792	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHAKHEAG_01793	5.54e-125	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
MHAKHEAG_01794	1.79e-304	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MHAKHEAG_01795	1.15e-259	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MHAKHEAG_01796	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MHAKHEAG_01797	3.88e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
MHAKHEAG_01798	2.02e-225	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
MHAKHEAG_01799	4.15e-120	jag	-	-	S	ko:K06346	-	ko00000	Putative single-stranded nucleic acids-binding domain
MHAKHEAG_01800	4.29e-161	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
MHAKHEAG_01801	3.68e-230	parA	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
MHAKHEAG_01802	1.7e-313	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MHAKHEAG_01803	6.8e-259	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MHAKHEAG_01804	0.0	mviN	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
MHAKHEAG_01805	0.0	-	-	-	M	-	-	-	Conserved repeat domain
MHAKHEAG_01806	3.18e-160	mutT4	-	-	L	-	-	-	Belongs to the Nudix hydrolase family
MHAKHEAG_01807	0.0	pcnA	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Probable RNA and SrmB- binding site of polymerase A
MHAKHEAG_01808	6.94e-146	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
MHAKHEAG_01809	2.19e-212	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MHAKHEAG_01810	8.92e-218	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MHAKHEAG_01811	1.08e-276	rpfB	-	-	S	ko:K21688	-	ko00000	G5
MHAKHEAG_01813	2.59e-201	-	-	-	O	-	-	-	Thioredoxin
MHAKHEAG_01814	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
MHAKHEAG_01815	3.11e-220	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MHAKHEAG_01816	2.18e-269	ugpC	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MHAKHEAG_01817	4.46e-132	-	-	-	L	-	-	-	Helix-turn-helix domain
MHAKHEAG_01818	0.0	-	-	-	S	-	-	-	LPXTG-motif cell wall anchor domain protein
MHAKHEAG_01819	1.52e-309	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MHAKHEAG_01820	5.45e-232	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MHAKHEAG_01821	7.99e-193	-	-	-	-	-	-	-	-
MHAKHEAG_01822	0.0	-	-	-	KLT	-	-	-	Domain of unknown function (DUF4032)
MHAKHEAG_01823	2.19e-223	rlmB	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHAKHEAG_01825	0.0	pacL2	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
MHAKHEAG_01826	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
MHAKHEAG_01827	6.04e-144	dcd	3.5.4.13	-	F	ko:K01494	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dCTP deaminase family
MHAKHEAG_01828	0.0	nhaP	-	-	P	ko:K03316	-	ko00000	Sodium/hydrogen exchanger family
MHAKHEAG_01829	2.7e-184	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
MHAKHEAG_01830	1.12e-109	tadA	3.5.4.1, 3.5.4.33	-	FJ	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MHAKHEAG_01831	5.39e-296	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
MHAKHEAG_01832	1.7e-185	cobB2	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
MHAKHEAG_01833	1.99e-80	-	-	-	L	-	-	-	single-stranded DNA binding
MHAKHEAG_01834	1.14e-68	-	-	-	-	-	-	-	-
MHAKHEAG_01835	5.43e-75	-	-	-	-	-	-	-	-
MHAKHEAG_01836	2.92e-48	-	-	-	-	-	-	-	-
MHAKHEAG_01837	1.36e-23	-	-	-	-	-	-	-	-
MHAKHEAG_01838	1.17e-65	-	-	-	-	-	-	-	-
MHAKHEAG_01839	9.04e-36	-	-	-	-	-	-	-	-
MHAKHEAG_01841	3.98e-65	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MHAKHEAG_01842	7.49e-09	-	-	-	-	-	-	-	-
MHAKHEAG_01843	9.92e-280	-	-	-	L	-	-	-	Phage integrase family
MHAKHEAG_01844	4.05e-17	-	-	-	V	-	-	-	HNH nucleases
MHAKHEAG_01847	1.81e-20	-	-	-	-	-	-	-	-
MHAKHEAG_01848	1.93e-276	-	-	-	S	-	-	-	Terminase
MHAKHEAG_01849	3.14e-50	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
MHAKHEAG_01850	1.05e-149	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
MHAKHEAG_01851	5.57e-72	-	-	-	-	-	-	-	-
MHAKHEAG_01852	3.86e-41	-	-	-	-	-	-	-	-
MHAKHEAG_01853	2.68e-172	-	-	-	S	-	-	-	Phage capsid family
MHAKHEAG_01854	1.64e-37	-	-	-	-	-	-	-	-
MHAKHEAG_01855	1.78e-67	-	-	-	S	-	-	-	Phage protein Gp19/Gp15/Gp42
MHAKHEAG_01856	6.92e-43	-	-	-	-	-	-	-	-
MHAKHEAG_01857	5.14e-97	-	-	-	N	-	-	-	domain, Protein
MHAKHEAG_01858	7.12e-39	-	-	-	-	-	-	-	-
MHAKHEAG_01859	2.4e-55	-	-	-	-	-	-	-	-
MHAKHEAG_01860	0.0	-	-	-	S	-	-	-	phage tail tape measure protein
MHAKHEAG_01861	3.45e-127	-	-	-	-	-	-	-	-
MHAKHEAG_01862	4.87e-280	-	-	-	S	-	-	-	Phage minor structural protein
MHAKHEAG_01863	3.88e-141	-	-	-	-	-	-	-	-
MHAKHEAG_01864	8.18e-49	-	-	-	-	-	-	-	-
MHAKHEAG_01866	2.34e-131	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
MHAKHEAG_01867	1.1e-29	-	-	-	-	-	-	-	-
MHAKHEAG_01868	6.05e-288	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
MHAKHEAG_01869	1.05e-286	-	-	-	S	-	-	-	MvaI/BcnI restriction endonuclease family
MHAKHEAG_01870	1.02e-89	-	-	-	-	-	-	-	-
MHAKHEAG_01871	3.17e-179	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2326)
MHAKHEAG_01872	2.88e-54	-	-	-	L	-	-	-	Transposase, Mutator family
MHAKHEAG_01873	4.67e-300	-	-	-	L	-	-	-	PFAM Integrase catalytic
MHAKHEAG_01874	1.35e-170	-	-	-	L	-	-	-	IstB-like ATP binding protein
MHAKHEAG_01875	2.31e-115	-	-	-	L	-	-	-	Transposase, Mutator family
MHAKHEAG_01877	4e-235	-	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
MHAKHEAG_01878	6.82e-25	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	carboxylic acid catabolic process
MHAKHEAG_01879	5.92e-26	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
MHAKHEAG_01880	1.03e-196	-	1.1.1.100, 1.1.1.413	-	IQ	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
MHAKHEAG_01883	1.55e-141	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MHAKHEAG_01884	1.59e-91	-	-	GT2	S	ko:K12992	ko02025,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyltransferase like family 2
MHAKHEAG_01885	3.38e-136	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	transferase activity, transferring glycosyl groups
MHAKHEAG_01886	1.24e-109	-	-	-	M	-	-	-	Polysaccharide pyruvyl transferase
MHAKHEAG_01889	6.84e-96	rgpC	-	-	GM	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
MHAKHEAG_01890	1.4e-203	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MHAKHEAG_01891	0.0	rfbD	1.1.1.133, 5.1.3.13	-	M	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MHAKHEAG_01892	4.29e-256	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MHAKHEAG_01893	2.86e-144	-	-	-	L	-	-	-	Transposase, Mutator family
MHAKHEAG_01894	6.46e-27	-	-	-	-	-	-	-	-
MHAKHEAG_01895	5.24e-298	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
MHAKHEAG_01896	1.26e-268	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
MHAKHEAG_01897	2.43e-40	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
MHAKHEAG_01898	3.55e-260	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MHAKHEAG_01899	1.79e-79	-	-	-	T	-	-	-	protein histidine kinase activity
MHAKHEAG_01900	1.05e-114	-	-	-	K	-	-	-	LytTr DNA-binding domain
MHAKHEAG_01901	1.22e-63	-	-	-	S	-	-	-	Protein of unknown function (DUF3073)
MHAKHEAG_01902	1.2e-261	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MHAKHEAG_01903	4.09e-249	-	-	-	S	-	-	-	Protein conserved in bacteria
MHAKHEAG_01904	2.14e-175	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family