ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
EHMLMMCA_00001 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EHMLMMCA_00002 5.7e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EHMLMMCA_00003 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EHMLMMCA_00004 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
EHMLMMCA_00005 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EHMLMMCA_00006 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EHMLMMCA_00007 1.01e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
EHMLMMCA_00008 2.58e-192 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
EHMLMMCA_00009 2.18e-96 - - - S - - - Bacterial PH domain
EHMLMMCA_00010 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
EHMLMMCA_00011 1.32e-189 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
EHMLMMCA_00012 1.3e-144 yyaC - - S - - - Sporulation protein YyaC
EHMLMMCA_00013 5.34e-227 yyaD - - S - - - Membrane
EHMLMMCA_00014 7.41e-45 yyzM - - S - - - protein conserved in bacteria
EHMLMMCA_00015 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EHMLMMCA_00016 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EHMLMMCA_00017 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
EHMLMMCA_00018 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EHMLMMCA_00019 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EHMLMMCA_00020 4.68e-184 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
EHMLMMCA_00021 6.85e-227 ccpB - - K - - - Transcriptional regulator
EHMLMMCA_00022 2.32e-86 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EHMLMMCA_00023 1.55e-128 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
EHMLMMCA_00024 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
EHMLMMCA_00025 4.94e-214 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
EHMLMMCA_00026 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
EHMLMMCA_00027 1.4e-314 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
EHMLMMCA_00028 7.09e-136 yyaP - - H - - - RibD C-terminal domain
EHMLMMCA_00029 1.82e-86 - - - S - - - YjbR
EHMLMMCA_00030 3.86e-119 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
EHMLMMCA_00031 1.23e-124 yyaS - - S ko:K07149 - ko00000 Membrane
EHMLMMCA_00032 8.79e-92 yjcF - - S - - - Acetyltransferase (GNAT) domain
EHMLMMCA_00033 4.54e-100 yybA - - K - - - transcriptional
EHMLMMCA_00034 4.18e-162 - - - S - - - Metallo-beta-lactamase superfamily
EHMLMMCA_00035 1.18e-72 yybC - - - - - - -
EHMLMMCA_00036 1.79e-100 yjcF - - S - - - Acetyltransferase (GNAT) domain
EHMLMMCA_00037 1.53e-209 yybE - - K - - - Transcriptional regulator
EHMLMMCA_00038 1.68e-274 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EHMLMMCA_00039 1.09e-159 yybG - - S - - - Pentapeptide repeat-containing protein
EHMLMMCA_00040 1.44e-86 - - - S - - - SnoaL-like domain
EHMLMMCA_00041 7.14e-184 - - - - - - - -
EHMLMMCA_00042 3.59e-141 - - - K - - - TipAS antibiotic-recognition domain
EHMLMMCA_00043 1.01e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EHMLMMCA_00045 1.3e-89 - - - - - - - -
EHMLMMCA_00046 4.89e-210 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
EHMLMMCA_00047 6.43e-88 yybR - - K - - - Transcriptional regulator
EHMLMMCA_00048 2.89e-110 cotF - - M ko:K06329 - ko00000 Spore coat protein
EHMLMMCA_00050 5.23e-205 yybS - - S - - - membrane
EHMLMMCA_00051 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
EHMLMMCA_00052 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
EHMLMMCA_00053 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EHMLMMCA_00054 1.2e-282 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
EHMLMMCA_00055 1.89e-22 yycC - - K - - - YycC-like protein
EHMLMMCA_00057 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
EHMLMMCA_00058 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
EHMLMMCA_00059 3.29e-99 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EHMLMMCA_00060 1.29e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EHMLMMCA_00065 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHMLMMCA_00066 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHMLMMCA_00067 0.0 yycH - - S - - - protein conserved in bacteria
EHMLMMCA_00068 2.83e-199 yycI - - S - - - protein conserved in bacteria
EHMLMMCA_00069 1.15e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
EHMLMMCA_00070 1.56e-277 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EHMLMMCA_00071 1.23e-41 - - - S - - - Peptidase propeptide and YPEB domain
EHMLMMCA_00072 8.13e-99 - - - S - - - Peptidase propeptide and YPEB domain
EHMLMMCA_00073 2.36e-122 - - - K ko:K02483 - ko00000,ko02022 PFAM response regulator receiver
EHMLMMCA_00074 9.16e-215 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
EHMLMMCA_00075 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
EHMLMMCA_00076 2.38e-293 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
EHMLMMCA_00077 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EHMLMMCA_00078 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
EHMLMMCA_00080 2.04e-237 - - - S - - - aspartate phosphatase
EHMLMMCA_00081 3.69e-111 yycN - - K - - - Acetyltransferase
EHMLMMCA_00082 1.68e-169 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EHMLMMCA_00083 1.01e-271 yycP - - - - - - -
EHMLMMCA_00084 2.24e-41 yycQ - - S - - - Protein of unknown function (DUF2651)
EHMLMMCA_00086 1.81e-297 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
EHMLMMCA_00087 8.12e-90 - - - - - - - -
EHMLMMCA_00089 1.01e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EHMLMMCA_00091 1.23e-134 - - - L - - - reverse transcriptase
EHMLMMCA_00092 1.36e-141 - - - S - - - Caspase domain
EHMLMMCA_00093 3.64e-56 - - - S - - - MazG-like family
EHMLMMCA_00094 6.93e-310 - - - L ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
EHMLMMCA_00095 7.08e-222 - - - L - - - AAA domain
EHMLMMCA_00096 3.66e-157 - - - L - - - AAA domain
EHMLMMCA_00097 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
EHMLMMCA_00098 2.4e-23 - - - - - - - -
EHMLMMCA_00099 8.64e-163 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
EHMLMMCA_00100 1.34e-15 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHMLMMCA_00101 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EHMLMMCA_00102 3.18e-237 - - - S - - - Polysaccharide pyruvyl transferase
EHMLMMCA_00103 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
EHMLMMCA_00104 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
EHMLMMCA_00105 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EHMLMMCA_00106 1.18e-294 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
EHMLMMCA_00107 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
EHMLMMCA_00108 2.1e-162 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
EHMLMMCA_00109 4.04e-264 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
EHMLMMCA_00110 7.3e-245 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
EHMLMMCA_00111 1.27e-152 yxaC - - M - - - effector of murein hydrolase
EHMLMMCA_00112 2.53e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
EHMLMMCA_00113 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
EHMLMMCA_00114 5.23e-256 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
EHMLMMCA_00115 3.91e-130 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
EHMLMMCA_00116 1.31e-244 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
EHMLMMCA_00117 4.77e-289 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
EHMLMMCA_00118 5.34e-37 yxaI - - S - - - membrane protein domain
EHMLMMCA_00119 5.13e-54 yxaI - - S - - - membrane protein domain
EHMLMMCA_00120 1.43e-85 - - - S - - - Family of unknown function (DUF5391)
EHMLMMCA_00121 7.49e-137 yxaL - - S - - - PQQ-like domain
EHMLMMCA_00122 1.8e-271 yxaM - - U - - - MFS_1 like family
EHMLMMCA_00123 0.0 - 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
EHMLMMCA_00124 8.99e-114 yxnB - - - - - - -
EHMLMMCA_00125 3.65e-59 - - - S - - - Coenzyme PQQ synthesis protein D (PqqD)
EHMLMMCA_00126 7.46e-177 yxbB - - Q - - - Met-10+ like-protein
EHMLMMCA_00127 1.16e-239 - - - S - - - A domain family that is part of the cupin metalloenzyme superfamily.
EHMLMMCA_00128 6.59e-111 yxbD 3.2.2.20 - K ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Acetyltransferase (GNAT) domain
EHMLMMCA_00129 7.19e-315 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EHMLMMCA_00130 2.54e-266 yxbF - - K - - - Bacterial regulatory proteins, tetR family
EHMLMMCA_00131 8.38e-193 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
EHMLMMCA_00133 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
EHMLMMCA_00134 1.02e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EHMLMMCA_00135 2.13e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
EHMLMMCA_00137 3.52e-224 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
EHMLMMCA_00138 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
EHMLMMCA_00139 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EHMLMMCA_00140 2.43e-200 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
EHMLMMCA_00141 3.52e-227 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
EHMLMMCA_00142 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
EHMLMMCA_00143 4.27e-223 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
EHMLMMCA_00144 1.99e-296 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
EHMLMMCA_00145 2.57e-250 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
EHMLMMCA_00146 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
EHMLMMCA_00147 3.79e-187 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
EHMLMMCA_00148 6.95e-205 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
EHMLMMCA_00149 3.27e-159 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHMLMMCA_00150 1.1e-230 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHMLMMCA_00151 3.82e-181 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EHMLMMCA_00152 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
EHMLMMCA_00153 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
EHMLMMCA_00154 4.1e-224 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EHMLMMCA_00155 9.65e-91 - - - - - - - -
EHMLMMCA_00156 7.57e-28 yxeD - - - - - - -
EHMLMMCA_00157 7.32e-42 yxeE - - - - - - -
EHMLMMCA_00160 8.09e-194 yxeH - - S - - - hydrolases of the HAD superfamily
EHMLMMCA_00161 1.35e-237 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
EHMLMMCA_00163 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHMLMMCA_00164 2.19e-121 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EHMLMMCA_00165 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
EHMLMMCA_00166 3e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
EHMLMMCA_00167 6.82e-171 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EHMLMMCA_00168 1.17e-271 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
EHMLMMCA_00169 8.39e-314 yxeQ - - S - - - MmgE/PrpD family
EHMLMMCA_00170 1.74e-252 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
EHMLMMCA_00171 1.24e-195 - - - S - - - Domain of Unknown Function (DUF1206)
EHMLMMCA_00172 2.02e-220 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
EHMLMMCA_00173 4.8e-149 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EHMLMMCA_00174 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EHMLMMCA_00175 4.02e-299 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
EHMLMMCA_00176 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EHMLMMCA_00177 3.98e-230 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
EHMLMMCA_00178 5.04e-296 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
EHMLMMCA_00179 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EHMLMMCA_00180 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
EHMLMMCA_00181 2.01e-102 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
EHMLMMCA_00182 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
EHMLMMCA_00183 2.01e-193 - - - L - - - Protein of unknown function (DUF2726)
EHMLMMCA_00184 1.23e-78 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
EHMLMMCA_00185 0.0 - - - L - - - HKD family nuclease
EHMLMMCA_00186 5.38e-37 - - - S - - - Domain of unknown function (DUF5082)
EHMLMMCA_00187 1.33e-52 yxiC - - S - - - Family of unknown function (DUF5344)
EHMLMMCA_00188 2.49e-270 - - - S - - - nuclease activity
EHMLMMCA_00189 8.65e-60 - - - - - - - -
EHMLMMCA_00190 6.06e-37 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2247)
EHMLMMCA_00191 7.97e-27 - - - - - - - -
EHMLMMCA_00192 4.03e-28 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2247)
EHMLMMCA_00193 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHMLMMCA_00194 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EHMLMMCA_00195 5.75e-93 yxiE - - T - - - Belongs to the universal stress protein A family
EHMLMMCA_00196 2.77e-35 - - - S - - - Sporulation delaying protein SdpA
EHMLMMCA_00197 1.24e-113 - - - - - - - -
EHMLMMCA_00199 2.01e-75 - - - K - - - helix_turn_helix, mercury resistance
EHMLMMCA_00200 8.44e-210 yxxF - - EG - - - EamA-like transporter family
EHMLMMCA_00201 0.0 wapA - - M - - - COG3209 Rhs family protein
EHMLMMCA_00202 1.09e-94 yxxG - - - - - - -
EHMLMMCA_00203 3.69e-111 - - - - - - - -
EHMLMMCA_00204 1.12e-82 - - - - - - - -
EHMLMMCA_00205 8.76e-99 yxiG - - - - - - -
EHMLMMCA_00206 1.85e-177 - - - - - - - -
EHMLMMCA_00207 1.43e-120 yxiI - - S - - - Protein of unknown function (DUF2716)
EHMLMMCA_00208 5.55e-56 yxiJ - - S - - - YxiJ-like protein
EHMLMMCA_00211 1.54e-268 - - - E - - - GDSL-like Lipase/Acylhydrolase
EHMLMMCA_00212 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
EHMLMMCA_00213 1.33e-292 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
EHMLMMCA_00214 1.78e-141 - - - - - - - -
EHMLMMCA_00215 4.65e-192 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
EHMLMMCA_00216 1.52e-184 bglS - - M - - - licheninase activity
EHMLMMCA_00217 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
EHMLMMCA_00218 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
EHMLMMCA_00219 2.28e-63 yxiS - - - - - - -
EHMLMMCA_00220 4.89e-132 - - - T - - - Domain of unknown function (DUF4163)
EHMLMMCA_00221 2.98e-269 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EHMLMMCA_00222 4.01e-200 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
EHMLMMCA_00223 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
EHMLMMCA_00224 3.82e-167 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EHMLMMCA_00225 2.41e-150 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
EHMLMMCA_00226 2.77e-174 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
EHMLMMCA_00227 1.55e-275 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
EHMLMMCA_00228 3.68e-278 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
EHMLMMCA_00229 2.03e-111 yxjI - - S - - - LURP-one-related
EHMLMMCA_00232 4.49e-298 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
EHMLMMCA_00233 7.4e-146 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
EHMLMMCA_00234 1.37e-258 - - - T - - - Signal transduction histidine kinase
EHMLMMCA_00235 7.69e-100 - - - S - - - Protein of unknown function (DUF1453)
EHMLMMCA_00236 3.62e-212 - - - K - - - LysR substrate binding domain
EHMLMMCA_00237 7.88e-121 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
EHMLMMCA_00238 4.98e-250 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
EHMLMMCA_00239 1.17e-98 yxkC - - S - - - Domain of unknown function (DUF4352)
EHMLMMCA_00240 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
EHMLMMCA_00241 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EHMLMMCA_00242 2.25e-209 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
EHMLMMCA_00243 1.4e-260 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHMLMMCA_00244 8.75e-198 yxkH - - G - - - Polysaccharide deacetylase
EHMLMMCA_00246 0.0 - - - O - - - Peptidase family M48
EHMLMMCA_00247 3.97e-310 cimH - - C - - - COG3493 Na citrate symporter
EHMLMMCA_00248 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
EHMLMMCA_00249 3.34e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
EHMLMMCA_00250 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
EHMLMMCA_00251 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
EHMLMMCA_00252 7.23e-200 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EHMLMMCA_00253 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
EHMLMMCA_00254 1.29e-124 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EHMLMMCA_00255 4.05e-64 yxlC - - S - - - Family of unknown function (DUF5345)
EHMLMMCA_00256 2.92e-42 - - - - - - - -
EHMLMMCA_00257 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
EHMLMMCA_00258 5.52e-209 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHMLMMCA_00259 3.96e-179 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EHMLMMCA_00260 3.02e-275 yxlH - - EGP - - - Major Facilitator Superfamily
EHMLMMCA_00261 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
EHMLMMCA_00262 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
EHMLMMCA_00263 8.94e-28 yxzF - - - - - - -
EHMLMMCA_00264 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
EHMLMMCA_00265 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
EHMLMMCA_00266 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EHMLMMCA_00267 1.58e-50 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHMLMMCA_00268 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
EHMLMMCA_00269 1.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
EHMLMMCA_00270 1.38e-176 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
EHMLMMCA_00271 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EHMLMMCA_00272 1.38e-49 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHMLMMCA_00273 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
EHMLMMCA_00274 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHMLMMCA_00275 5.7e-210 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
EHMLMMCA_00276 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
EHMLMMCA_00277 1.3e-163 - - - EGP - - - Permeases of the major facilitator superfamily
EHMLMMCA_00278 5.58e-64 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
EHMLMMCA_00279 1.33e-116 - - - K - - - Helix-turn-helix XRE-family like proteins
EHMLMMCA_00280 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
EHMLMMCA_00281 2.9e-293 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EHMLMMCA_00282 3.57e-114 ywaE - - K - - - Transcriptional regulator
EHMLMMCA_00283 3.49e-158 ywaF - - S - - - Integral membrane protein
EHMLMMCA_00284 4.41e-215 gspA - - M - - - General stress
EHMLMMCA_00285 2.6e-195 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
EHMLMMCA_00286 2.79e-310 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHMLMMCA_00287 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EHMLMMCA_00288 1.5e-313 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EHMLMMCA_00289 4.01e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
EHMLMMCA_00290 1.15e-279 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
EHMLMMCA_00291 6.33e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
EHMLMMCA_00292 1.76e-276 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
EHMLMMCA_00293 1.21e-143 ywbG - - M - - - effector of murein hydrolase
EHMLMMCA_00294 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
EHMLMMCA_00295 2.7e-203 ywbI - - K - - - Transcriptional regulator
EHMLMMCA_00296 1.32e-184 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EHMLMMCA_00297 7.07e-146 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
EHMLMMCA_00298 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
EHMLMMCA_00299 2.42e-246 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
EHMLMMCA_00300 1.04e-306 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
EHMLMMCA_00301 1.26e-144 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
EHMLMMCA_00302 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHMLMMCA_00303 7.41e-65 ywcB - - S - - - Protein of unknown function, DUF485
EHMLMMCA_00305 3.42e-158 ywcC - - K - - - transcriptional regulator
EHMLMMCA_00306 3.33e-77 gtcA - - S - - - GtrA-like protein
EHMLMMCA_00307 9.22e-290 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EHMLMMCA_00308 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
EHMLMMCA_00309 5.11e-49 ydaS - - S - - - membrane
EHMLMMCA_00310 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
EHMLMMCA_00311 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EHMLMMCA_00312 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
EHMLMMCA_00313 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
EHMLMMCA_00314 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
EHMLMMCA_00315 8.89e-269 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
EHMLMMCA_00316 2.31e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
EHMLMMCA_00317 2.83e-237 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHMLMMCA_00318 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EHMLMMCA_00320 1.29e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
EHMLMMCA_00321 2.79e-178 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
EHMLMMCA_00322 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHMLMMCA_00323 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
EHMLMMCA_00324 6.19e-39 ywdA - - - - - - -
EHMLMMCA_00325 2.21e-187 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
EHMLMMCA_00326 7.92e-76 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
EHMLMMCA_00327 2.4e-143 ywdD - - - - - - -
EHMLMMCA_00329 4.68e-192 ywdF - - S - - - Glycosyltransferase like family 2
EHMLMMCA_00330 9.47e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EHMLMMCA_00331 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EHMLMMCA_00332 3.76e-64 ywdI - - S - - - Family of unknown function (DUF5327)
EHMLMMCA_00333 2.17e-302 ywdJ - - F - - - Xanthine uracil
EHMLMMCA_00334 1.59e-78 ywdK - - S - - - small membrane protein
EHMLMMCA_00335 3.62e-112 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
EHMLMMCA_00336 1.15e-186 spsA - - M - - - Spore Coat
EHMLMMCA_00337 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
EHMLMMCA_00338 3.73e-284 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
EHMLMMCA_00339 1.72e-209 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
EHMLMMCA_00340 3.93e-271 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
EHMLMMCA_00341 1.28e-166 spsF - - M ko:K07257 - ko00000 Spore Coat
EHMLMMCA_00342 1.16e-239 spsG - - M - - - Spore Coat
EHMLMMCA_00343 7.45e-178 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EHMLMMCA_00344 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EHMLMMCA_00345 1.41e-205 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EHMLMMCA_00346 9.16e-114 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
EHMLMMCA_00347 3.7e-101 - - - - - - - -
EHMLMMCA_00348 2.11e-310 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
EHMLMMCA_00349 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
EHMLMMCA_00350 0.0 rocB - - E - - - arginine degradation protein
EHMLMMCA_00351 8.84e-317 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EHMLMMCA_00352 6.3e-274 ywfA - - EGP - - - -transporter
EHMLMMCA_00353 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
EHMLMMCA_00354 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
EHMLMMCA_00355 4.47e-178 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHMLMMCA_00356 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
EHMLMMCA_00357 3.21e-267 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
EHMLMMCA_00358 4.46e-297 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
EHMLMMCA_00359 4.1e-177 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
EHMLMMCA_00360 1.4e-186 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
EHMLMMCA_00361 1.67e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
EHMLMMCA_00362 1.25e-207 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
EHMLMMCA_00363 2.15e-199 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
EHMLMMCA_00364 1.57e-204 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
EHMLMMCA_00365 1.88e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
EHMLMMCA_00366 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
EHMLMMCA_00367 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
EHMLMMCA_00368 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
EHMLMMCA_00369 1.1e-103 yffB - - K - - - Transcriptional regulator
EHMLMMCA_00370 6.75e-304 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
EHMLMMCA_00372 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EHMLMMCA_00373 1.45e-93 ywhA - - K - - - Transcriptional regulator
EHMLMMCA_00374 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
EHMLMMCA_00375 3.29e-154 ywhC - - S - - - Peptidase family M50
EHMLMMCA_00376 7.83e-123 ywhD - - S - - - YwhD family
EHMLMMCA_00377 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
EHMLMMCA_00378 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EHMLMMCA_00379 2.99e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
EHMLMMCA_00381 7.42e-77 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
EHMLMMCA_00384 1.52e-14 - - - S - - - ABC-2 family transporter protein
EHMLMMCA_00387 2.32e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
EHMLMMCA_00388 9.47e-275 ywhK - - CO - - - amine dehydrogenase activity
EHMLMMCA_00389 0.0 ywhL - - CO - - - amine dehydrogenase activity
EHMLMMCA_00391 3.9e-316 - - - L - - - Peptidase, M16
EHMLMMCA_00392 8.09e-275 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
EHMLMMCA_00393 2.41e-297 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
EHMLMMCA_00394 3.03e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
EHMLMMCA_00396 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
EHMLMMCA_00397 3.71e-12 - - - S - - - Bacteriocin subtilosin A
EHMLMMCA_00398 4.64e-96 ywiB - - S - - - protein conserved in bacteria
EHMLMMCA_00399 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
EHMLMMCA_00400 1.7e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
EHMLMMCA_00401 2.3e-168 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
EHMLMMCA_00402 1.84e-179 ywiC - - S - - - YwiC-like protein
EHMLMMCA_00403 7.13e-110 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
EHMLMMCA_00404 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EHMLMMCA_00405 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
EHMLMMCA_00406 3.23e-121 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
EHMLMMCA_00407 1.02e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
EHMLMMCA_00408 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EHMLMMCA_00409 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
EHMLMMCA_00410 1.06e-121 ywjB - - H - - - RibD C-terminal domain
EHMLMMCA_00411 1.32e-57 ywjC - - - - - - -
EHMLMMCA_00412 9.85e-236 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
EHMLMMCA_00413 3.34e-287 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
EHMLMMCA_00414 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
EHMLMMCA_00415 9.98e-268 acdA - - I - - - acyl-CoA dehydrogenase
EHMLMMCA_00416 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EHMLMMCA_00417 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EHMLMMCA_00418 3.18e-118 ywjG - - S - - - Domain of unknown function (DUF2529)
EHMLMMCA_00419 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
EHMLMMCA_00420 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
EHMLMMCA_00421 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EHMLMMCA_00422 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EHMLMMCA_00423 2.03e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
EHMLMMCA_00424 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EHMLMMCA_00425 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
EHMLMMCA_00426 4.93e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
EHMLMMCA_00427 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
EHMLMMCA_00428 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
EHMLMMCA_00429 6.01e-117 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
EHMLMMCA_00430 1.39e-88 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EHMLMMCA_00431 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EHMLMMCA_00432 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EHMLMMCA_00434 9.69e-74 ywlA - - S - - - Uncharacterised protein family (UPF0715)
EHMLMMCA_00435 1.14e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
EHMLMMCA_00436 1.79e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
EHMLMMCA_00437 7.37e-251 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EHMLMMCA_00438 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
EHMLMMCA_00439 1.58e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EHMLMMCA_00440 1.36e-105 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
EHMLMMCA_00441 2.9e-122 ywlG - - S - - - Belongs to the UPF0340 family
EHMLMMCA_00442 4.36e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EHMLMMCA_00443 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EHMLMMCA_00444 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
EHMLMMCA_00445 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
EHMLMMCA_00446 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EHMLMMCA_00447 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EHMLMMCA_00448 2.89e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EHMLMMCA_00449 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EHMLMMCA_00450 4.46e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EHMLMMCA_00451 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EHMLMMCA_00452 3.89e-72 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
EHMLMMCA_00453 1.19e-112 ywmA - - - - - - -
EHMLMMCA_00454 4.54e-45 ywzB - - S - - - membrane
EHMLMMCA_00455 2.2e-170 ywmB - - S - - - TATA-box binding
EHMLMMCA_00456 4.96e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EHMLMMCA_00457 2.8e-233 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
EHMLMMCA_00458 1.89e-157 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
EHMLMMCA_00459 1.02e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
EHMLMMCA_00461 2.22e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EHMLMMCA_00462 2.65e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EHMLMMCA_00463 1.25e-128 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
EHMLMMCA_00464 1.21e-109 ywmF - - S - - - Peptidase M50
EHMLMMCA_00465 1.11e-21 csbD - - K - - - CsbD-like
EHMLMMCA_00466 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
EHMLMMCA_00467 1.12e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
EHMLMMCA_00468 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
EHMLMMCA_00469 2.65e-84 ywnA - - K - - - Transcriptional regulator
EHMLMMCA_00470 1.97e-143 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
EHMLMMCA_00471 3.55e-77 ywnC - - S - - - Family of unknown function (DUF5362)
EHMLMMCA_00472 9.39e-182 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
EHMLMMCA_00473 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EHMLMMCA_00474 7.07e-92 ywnF - - S - - - Family of unknown function (DUF5392)
EHMLMMCA_00475 1.01e-17 ywnC - - S - - - Family of unknown function (DUF5362)
EHMLMMCA_00476 7.38e-115 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
EHMLMMCA_00477 1.85e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
EHMLMMCA_00478 7.75e-94 ywnJ - - S - - - VanZ like family
EHMLMMCA_00479 1.21e-134 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
EHMLMMCA_00480 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
EHMLMMCA_00481 6.5e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
EHMLMMCA_00482 5.89e-100 - - - - - - - -
EHMLMMCA_00483 1.48e-133 yjgF - - Q - - - Isochorismatase family
EHMLMMCA_00484 1.54e-306 ywoD - - EGP - - - Major facilitator superfamily
EHMLMMCA_00485 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
EHMLMMCA_00486 2.92e-312 ywoF - - P - - - Right handed beta helix region
EHMLMMCA_00487 3.92e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EHMLMMCA_00488 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
EHMLMMCA_00489 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
EHMLMMCA_00490 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
EHMLMMCA_00491 8.4e-171 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
EHMLMMCA_00492 1.17e-181 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
EHMLMMCA_00493 1.5e-254 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
EHMLMMCA_00494 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EHMLMMCA_00495 3.25e-77 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EHMLMMCA_00496 4.66e-186 ywpD - - T - - - Histidine kinase
EHMLMMCA_00497 2.21e-66 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
EHMLMMCA_00498 3.59e-88 ywpF - - S - - - YwpF-like protein
EHMLMMCA_00499 3.56e-86 ywpG - - - - - - -
EHMLMMCA_00500 1.04e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
EHMLMMCA_00501 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
EHMLMMCA_00502 2.51e-200 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
EHMLMMCA_00503 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
EHMLMMCA_00504 0.0 ywqB - - S - - - SWIM zinc finger
EHMLMMCA_00505 3.6e-25 - - - - - - - -
EHMLMMCA_00506 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
EHMLMMCA_00507 1.06e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
EHMLMMCA_00508 6.38e-183 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
EHMLMMCA_00509 2.21e-311 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EHMLMMCA_00510 1.64e-193 ywqG - - S - - - Domain of unknown function (DUF1963)
EHMLMMCA_00512 8.84e-52 ywqI - - S - - - Family of unknown function (DUF5344)
EHMLMMCA_00513 1.01e-302 ywqJ - - S - - - Pre-toxin TG
EHMLMMCA_00515 7.19e-149 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
EHMLMMCA_00516 9.54e-209 - - - K - - - Transcriptional regulator
EHMLMMCA_00517 1.5e-129 ywqN - - S - - - NAD(P)H-dependent
EHMLMMCA_00519 3.51e-113 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
EHMLMMCA_00520 1.07e-130 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
EHMLMMCA_00521 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
EHMLMMCA_00522 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
EHMLMMCA_00523 2.78e-71 - - - S - - - Domain of unknown function (DUF4181)
EHMLMMCA_00524 4.35e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EHMLMMCA_00525 2.17e-16 - - - - - - - -
EHMLMMCA_00526 1.12e-269 cotH - - M ko:K06330 - ko00000 Spore Coat
EHMLMMCA_00527 1.43e-182 cotB - - - ko:K06325 - ko00000 -
EHMLMMCA_00528 4.33e-162 ywrJ - - - - - - -
EHMLMMCA_00529 2.79e-280 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EHMLMMCA_00530 3.36e-218 alsR - - K - - - LysR substrate binding domain
EHMLMMCA_00531 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
EHMLMMCA_00532 1.84e-187 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
EHMLMMCA_00533 2.15e-126 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
EHMLMMCA_00534 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
EHMLMMCA_00535 4.83e-120 batE - - T - - - Sh3 type 3 domain protein
EHMLMMCA_00536 1.28e-203 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
EHMLMMCA_00537 1.93e-202 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
EHMLMMCA_00538 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
EHMLMMCA_00539 4.61e-84 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
EHMLMMCA_00540 1.77e-204 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHMLMMCA_00541 2.68e-227 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
EHMLMMCA_00542 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
EHMLMMCA_00543 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
EHMLMMCA_00544 1.33e-277 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
EHMLMMCA_00545 2.29e-29 ywtC - - - - - - -
EHMLMMCA_00546 9.23e-303 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
EHMLMMCA_00547 6.95e-203 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
EHMLMMCA_00548 4.95e-221 ywtF_2 - - K - - - Transcriptional regulator
EHMLMMCA_00549 3.18e-315 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EHMLMMCA_00550 3.25e-275 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
EHMLMMCA_00551 1.24e-256 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
EHMLMMCA_00552 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
EHMLMMCA_00553 1.58e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
EHMLMMCA_00554 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EHMLMMCA_00555 1.42e-235 tarL 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
EHMLMMCA_00556 6.69e-110 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - M ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
EHMLMMCA_00557 5.68e-186 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
EHMLMMCA_00558 1.46e-134 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
EHMLMMCA_00559 5.44e-117 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EHMLMMCA_00560 6.82e-111 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
EHMLMMCA_00561 1.32e-73 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
EHMLMMCA_00562 6.32e-167 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EHMLMMCA_00563 2.57e-135 - - - M - - - Glycosyltransferase like family 2
EHMLMMCA_00564 2.93e-102 - - - - - - - -
EHMLMMCA_00565 6.73e-165 - - - M - - - Glycosyltransferase like family 2
EHMLMMCA_00566 3.08e-181 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
EHMLMMCA_00567 1.95e-167 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
EHMLMMCA_00568 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
EHMLMMCA_00569 2.74e-208 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
EHMLMMCA_00571 3.43e-118 - - - M - - - Glycosyl transferases group 1
EHMLMMCA_00572 1.48e-103 - - - M - - - Glycosyltransferase like family 2
EHMLMMCA_00573 1.17e-271 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
EHMLMMCA_00574 1.16e-211 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
EHMLMMCA_00575 9.07e-16 - - - - - - - -
EHMLMMCA_00576 0.0 lytB - - D - - - Stage II sporulation protein
EHMLMMCA_00577 5.54e-266 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
EHMLMMCA_00578 1.78e-108 - - - M - - - Glycosyltransferase like family 2
EHMLMMCA_00579 1.49e-143 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
EHMLMMCA_00580 1.46e-315 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EHMLMMCA_00581 3.83e-277 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
EHMLMMCA_00582 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EHMLMMCA_00583 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
EHMLMMCA_00584 9.6e-146 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
EHMLMMCA_00585 8.42e-187 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
EHMLMMCA_00586 4.13e-297 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
EHMLMMCA_00587 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
EHMLMMCA_00588 4.43e-222 yvhJ - - K - - - Transcriptional regulator
EHMLMMCA_00589 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
EHMLMMCA_00590 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
EHMLMMCA_00591 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EHMLMMCA_00592 2.15e-199 degV - - S - - - protein conserved in bacteria
EHMLMMCA_00593 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EHMLMMCA_00594 4.22e-60 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
EHMLMMCA_00595 2.26e-162 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
EHMLMMCA_00596 1.83e-96 yvyF - - S - - - flagellar protein
EHMLMMCA_00597 4.32e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
EHMLMMCA_00598 2.02e-101 yvyG - - NOU - - - FlgN protein
EHMLMMCA_00599 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
EHMLMMCA_00600 3.8e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
EHMLMMCA_00601 1.7e-92 yviE - - - - - - -
EHMLMMCA_00602 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
EHMLMMCA_00603 3.02e-40 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EHMLMMCA_00604 1.43e-124 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHMLMMCA_00605 1.62e-69 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
EHMLMMCA_00606 1.27e-312 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EHMLMMCA_00607 5.15e-91 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
EHMLMMCA_00608 2.67e-07 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
EHMLMMCA_00609 3.72e-87 - - - - - - - -
EHMLMMCA_00610 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EHMLMMCA_00611 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EHMLMMCA_00612 8.14e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EHMLMMCA_00613 6.5e-185 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EHMLMMCA_00614 3.23e-75 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
EHMLMMCA_00615 1.5e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
EHMLMMCA_00616 1.1e-198 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
EHMLMMCA_00617 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
EHMLMMCA_00618 1.38e-73 swrA - - S - - - Swarming motility protein
EHMLMMCA_00619 6.4e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EHMLMMCA_00620 7.12e-294 yvkA - - P - - - -transporter
EHMLMMCA_00621 1.43e-131 yvkB - - K - - - Transcriptional regulator
EHMLMMCA_00622 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
EHMLMMCA_00623 2.54e-42 csbA - - S - - - protein conserved in bacteria
EHMLMMCA_00624 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EHMLMMCA_00625 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EHMLMMCA_00626 1.23e-146 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHMLMMCA_00627 2.25e-45 yvkN - - - - - - -
EHMLMMCA_00628 8.09e-65 yvlA - - - - - - -
EHMLMMCA_00629 5.8e-221 yvlB - - S - - - Putative adhesin
EHMLMMCA_00630 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
EHMLMMCA_00631 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
EHMLMMCA_00632 4.07e-270 yvmA - - EGP - - - Major Facilitator Superfamily
EHMLMMCA_00633 6.2e-114 yvmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
EHMLMMCA_00634 8.35e-176 yvmC 2.3.2.22 - S ko:K17485 - ko00000,ko01000 Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
EHMLMMCA_00635 4.24e-289 cypX 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EHMLMMCA_00636 2.01e-94 yvnA - - K - - - helix_turn_helix multiple antibiotic resistance protein
EHMLMMCA_00637 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
EHMLMMCA_00638 3.02e-171 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
EHMLMMCA_00639 2.37e-163 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EHMLMMCA_00640 5.07e-281 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
EHMLMMCA_00641 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EHMLMMCA_00642 1.29e-194 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EHMLMMCA_00643 3.05e-210 yvoD - - P - - - COG0370 Fe2 transport system protein B
EHMLMMCA_00644 3.56e-152 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
EHMLMMCA_00645 1.69e-108 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
EHMLMMCA_00646 1.1e-153 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
EHMLMMCA_00647 2.49e-178 yvpB - - NU - - - protein conserved in bacteria
EHMLMMCA_00648 6.64e-279 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EHMLMMCA_00649 2.5e-146 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
EHMLMMCA_00650 3e-291 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EHMLMMCA_00651 2.87e-138 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
EHMLMMCA_00652 1.2e-148 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EHMLMMCA_00653 3.95e-168 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EHMLMMCA_00654 9.74e-177 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EHMLMMCA_00655 5.91e-143 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
EHMLMMCA_00656 8.75e-91 - - - - - - - -
EHMLMMCA_00657 5.25e-111 - - - - - - - -
EHMLMMCA_00658 0.0 - - - - - - - -
EHMLMMCA_00660 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
EHMLMMCA_00661 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
EHMLMMCA_00662 1.08e-184 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
EHMLMMCA_00663 8.31e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EHMLMMCA_00664 9.76e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
EHMLMMCA_00665 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
EHMLMMCA_00666 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
EHMLMMCA_00667 3.63e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
EHMLMMCA_00668 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
EHMLMMCA_00669 2.3e-182 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
EHMLMMCA_00670 1.32e-43 - - - - - - - -
EHMLMMCA_00671 4.67e-172 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHMLMMCA_00672 2.38e-252 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
EHMLMMCA_00673 4.46e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EHMLMMCA_00674 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
EHMLMMCA_00675 2.32e-234 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHMLMMCA_00676 3.73e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
EHMLMMCA_00677 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
EHMLMMCA_00678 4.54e-70 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
EHMLMMCA_00679 4.42e-136 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
EHMLMMCA_00680 1.54e-221 yvdE - - K - - - Transcriptional regulator
EHMLMMCA_00681 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
EHMLMMCA_00682 1.63e-299 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
EHMLMMCA_00683 8.65e-311 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
EHMLMMCA_00684 6.84e-190 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
EHMLMMCA_00685 3.96e-197 malA - - S - - - Protein of unknown function (DUF1189)
EHMLMMCA_00686 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
EHMLMMCA_00687 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
EHMLMMCA_00688 2.91e-156 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
EHMLMMCA_00689 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EHMLMMCA_00691 9.45e-234 - - - S - - - Patatin-like phospholipase
EHMLMMCA_00692 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
EHMLMMCA_00693 5.53e-122 yvdQ - - S - - - Protein of unknown function (DUF3231)
EHMLMMCA_00694 1.03e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
EHMLMMCA_00695 2.57e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
EHMLMMCA_00696 4.76e-137 yvdT_1 - - K - - - Transcriptional regulator
EHMLMMCA_00697 0.0 ybeC - - E - - - amino acid
EHMLMMCA_00698 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
EHMLMMCA_00699 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
EHMLMMCA_00700 0.0 pbpE - - V - - - Beta-lactamase
EHMLMMCA_00701 1.69e-160 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
EHMLMMCA_00702 9.03e-96 - - - S - - - Protein of unknown function (DUF3237)
EHMLMMCA_00703 3.13e-119 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
EHMLMMCA_00705 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
EHMLMMCA_00706 3.57e-98 - - - K ko:K19417 - ko00000,ko03000 transcriptional
EHMLMMCA_00707 2.78e-158 epsA - - M ko:K19420 - ko00000 biosynthesis protein
EHMLMMCA_00708 7.94e-150 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
EHMLMMCA_00709 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
EHMLMMCA_00710 2.32e-283 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
EHMLMMCA_00711 5.09e-201 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
EHMLMMCA_00712 4.43e-273 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
EHMLMMCA_00713 1.03e-263 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
EHMLMMCA_00714 3.5e-248 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
EHMLMMCA_00715 1.91e-259 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
EHMLMMCA_00716 8.59e-249 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
EHMLMMCA_00717 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EHMLMMCA_00718 6.7e-141 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
EHMLMMCA_00719 9.38e-80 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
EHMLMMCA_00720 5.25e-279 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
EHMLMMCA_00721 1.03e-238 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
EHMLMMCA_00722 5.69e-44 yvfG - - S - - - YvfG protein
EHMLMMCA_00723 1.66e-304 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
EHMLMMCA_00724 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
EHMLMMCA_00725 6.85e-146 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
EHMLMMCA_00726 1.51e-235 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
EHMLMMCA_00727 7.78e-286 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
EHMLMMCA_00728 1.24e-299 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
EHMLMMCA_00729 7.72e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
EHMLMMCA_00730 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
EHMLMMCA_00731 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
EHMLMMCA_00732 8.02e-261 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
EHMLMMCA_00733 7.25e-201 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
EHMLMMCA_00734 5.95e-209 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
EHMLMMCA_00735 4.81e-169 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
EHMLMMCA_00736 7.33e-250 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHMLMMCA_00737 2.52e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EHMLMMCA_00738 2.6e-174 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
EHMLMMCA_00739 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
EHMLMMCA_00740 2.92e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
EHMLMMCA_00741 1.22e-248 - - - S - - - Glycosyl hydrolase
EHMLMMCA_00742 1.43e-306 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
EHMLMMCA_00743 3.93e-198 yvbV - - EG - - - EamA-like transporter family
EHMLMMCA_00744 5.49e-205 yvbU - - K - - - Transcriptional regulator
EHMLMMCA_00746 6.01e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHMLMMCA_00747 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
EHMLMMCA_00748 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EHMLMMCA_00749 2.42e-237 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
EHMLMMCA_00750 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EHMLMMCA_00751 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
EHMLMMCA_00752 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EHMLMMCA_00753 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
EHMLMMCA_00754 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EHMLMMCA_00755 6.87e-106 yvbK - - K - - - acetyltransferase
EHMLMMCA_00756 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
EHMLMMCA_00757 1.61e-156 yvbI - - M - - - Membrane
EHMLMMCA_00758 9.9e-144 yvbH - - S - - - YvbH-like oligomerisation region
EHMLMMCA_00759 7.95e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
EHMLMMCA_00760 8.29e-129 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
EHMLMMCA_00761 5.58e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
EHMLMMCA_00762 5.63e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
EHMLMMCA_00763 1.74e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EHMLMMCA_00764 9.67e-137 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
EHMLMMCA_00765 6.63e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
EHMLMMCA_00766 3.64e-271 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
EHMLMMCA_00767 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
EHMLMMCA_00768 1.95e-219 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EHMLMMCA_00769 2.26e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
EHMLMMCA_00770 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EHMLMMCA_00771 3.85e-72 yvaP - - K - - - transcriptional
EHMLMMCA_00772 9.82e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
EHMLMMCA_00773 4.08e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
EHMLMMCA_00774 3.44e-48 yvzC - - K - - - transcriptional
EHMLMMCA_00775 4.04e-194 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
EHMLMMCA_00776 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
EHMLMMCA_00777 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
EHMLMMCA_00778 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EHMLMMCA_00779 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EHMLMMCA_00781 3.96e-182 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
EHMLMMCA_00782 2.01e-127 - - - K - - - Bacterial regulatory proteins, tetR family
EHMLMMCA_00783 2.04e-70 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
EHMLMMCA_00784 8.22e-97 yvaD - - S - - - Family of unknown function (DUF5360)
EHMLMMCA_00785 0.0 - - - S - - - Fusaric acid resistance protein-like
EHMLMMCA_00786 3.59e-154 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EHMLMMCA_00787 5.71e-247 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
EHMLMMCA_00788 3.99e-64 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
EHMLMMCA_00789 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
EHMLMMCA_00790 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
EHMLMMCA_00791 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
EHMLMMCA_00792 3.45e-137 bdbD - - O - - - Thioredoxin
EHMLMMCA_00793 2.83e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
EHMLMMCA_00794 3.88e-140 yvgT - - S - - - membrane
EHMLMMCA_00795 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
EHMLMMCA_00796 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EHMLMMCA_00797 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
EHMLMMCA_00798 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
EHMLMMCA_00799 1.61e-112 yvgO - - - - - - -
EHMLMMCA_00800 2.63e-202 yvgN - - S - - - reductase
EHMLMMCA_00801 4.79e-151 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
EHMLMMCA_00802 1.8e-176 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
EHMLMMCA_00803 1.03e-213 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
EHMLMMCA_00804 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
EHMLMMCA_00805 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
EHMLMMCA_00806 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
EHMLMMCA_00807 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
EHMLMMCA_00808 1.09e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EHMLMMCA_00809 6e-237 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHMLMMCA_00810 4.78e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHMLMMCA_00811 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
EHMLMMCA_00812 1.15e-227 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
EHMLMMCA_00813 4.64e-159 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHMLMMCA_00814 6.32e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
EHMLMMCA_00815 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
EHMLMMCA_00816 9.23e-292 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
EHMLMMCA_00817 3.46e-26 - - - S - - - YvrJ protein family
EHMLMMCA_00818 1.66e-126 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
EHMLMMCA_00819 6.16e-33 - - - - - - - -
EHMLMMCA_00820 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHMLMMCA_00821 0.0 yvrG - - T - - - Histidine kinase
EHMLMMCA_00822 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
EHMLMMCA_00823 5.21e-182 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
EHMLMMCA_00824 5.15e-219 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
EHMLMMCA_00825 3.29e-237 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHMLMMCA_00826 0.0 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
EHMLMMCA_00827 8.21e-133 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
EHMLMMCA_00828 1.13e-288 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EHMLMMCA_00829 1.51e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
EHMLMMCA_00830 4.22e-144 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
EHMLMMCA_00831 6.57e-178 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
EHMLMMCA_00832 5.39e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
EHMLMMCA_00833 4.06e-246 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHMLMMCA_00834 9.39e-141 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EHMLMMCA_00835 3.48e-249 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
EHMLMMCA_00836 2.9e-253 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
EHMLMMCA_00837 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
EHMLMMCA_00838 4.48e-34 - - - S - - - Protein of unknown function (DUF3970)
EHMLMMCA_00839 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
EHMLMMCA_00840 8.41e-202 yuxN - - K - - - Transcriptional regulator
EHMLMMCA_00841 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHMLMMCA_00842 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHMLMMCA_00843 4.37e-302 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EHMLMMCA_00844 1.07e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
EHMLMMCA_00845 1.1e-196 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
EHMLMMCA_00846 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
EHMLMMCA_00847 3.48e-88 - - - S - - - YusW-like protein
EHMLMMCA_00848 1.06e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
EHMLMMCA_00849 3.01e-63 yusU - - S - - - Protein of unknown function (DUF2573)
EHMLMMCA_00850 3.43e-203 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
EHMLMMCA_00851 1.36e-135 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
EHMLMMCA_00852 4.16e-85 yusQ - - S - - - Tautomerase enzyme
EHMLMMCA_00853 0.0 yusP - - P - - - Major facilitator superfamily
EHMLMMCA_00854 6.09e-96 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
EHMLMMCA_00855 1.23e-69 yusN - - M - - - Coat F domain
EHMLMMCA_00856 2.23e-54 - - - - - - - -
EHMLMMCA_00857 1.41e-210 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
EHMLMMCA_00858 1.11e-13 - - - S - - - YuzL-like protein
EHMLMMCA_00859 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
EHMLMMCA_00860 3.84e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
EHMLMMCA_00861 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
EHMLMMCA_00862 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
EHMLMMCA_00863 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
EHMLMMCA_00864 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
EHMLMMCA_00865 2.18e-96 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
EHMLMMCA_00866 2e-73 yusE - - CO - - - Thioredoxin
EHMLMMCA_00867 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
EHMLMMCA_00868 1.24e-235 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EHMLMMCA_00869 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
EHMLMMCA_00870 5.86e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
EHMLMMCA_00871 1.56e-80 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EHMLMMCA_00872 4.46e-182 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
EHMLMMCA_00873 7.43e-313 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
EHMLMMCA_00874 2.81e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EHMLMMCA_00875 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
EHMLMMCA_00876 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
EHMLMMCA_00877 6.91e-84 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EHMLMMCA_00878 4.76e-56 - - - - - - - -
EHMLMMCA_00880 4.87e-260 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
EHMLMMCA_00881 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
EHMLMMCA_00882 1.29e-235 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
EHMLMMCA_00883 3.9e-305 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
EHMLMMCA_00884 3.54e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EHMLMMCA_00885 4.58e-215 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
EHMLMMCA_00886 5.31e-206 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
EHMLMMCA_00887 7.46e-176 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
EHMLMMCA_00888 2.42e-262 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHMLMMCA_00889 5.16e-215 bsn - - L - - - Ribonuclease
EHMLMMCA_00890 3.96e-293 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
EHMLMMCA_00891 3.32e-303 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
EHMLMMCA_00892 3.87e-238 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EHMLMMCA_00893 4.18e-141 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
EHMLMMCA_00894 6.5e-183 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
EHMLMMCA_00895 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
EHMLMMCA_00896 5.71e-121 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
EHMLMMCA_00897 2.01e-70 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
EHMLMMCA_00898 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
EHMLMMCA_00899 3.71e-282 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
EHMLMMCA_00900 1.99e-298 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
EHMLMMCA_00901 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
EHMLMMCA_00902 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
EHMLMMCA_00903 1.07e-79 yunG - - - - - - -
EHMLMMCA_00904 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
EHMLMMCA_00905 6.51e-181 yunE - - S ko:K07090 - ko00000 membrane transporter protein
EHMLMMCA_00906 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
EHMLMMCA_00907 5.67e-64 yunC - - S - - - Domain of unknown function (DUF1805)
EHMLMMCA_00908 2.46e-171 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
EHMLMMCA_00909 3.11e-251 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
EHMLMMCA_00910 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EHMLMMCA_00911 5.47e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EHMLMMCA_00912 3.2e-63 yutD - - S - - - protein conserved in bacteria
EHMLMMCA_00913 2.38e-99 yutE - - S - - - Protein of unknown function DUF86
EHMLMMCA_00914 2.49e-181 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EHMLMMCA_00915 3.21e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
EHMLMMCA_00916 1.55e-253 yutH - - S - - - Spore coat protein
EHMLMMCA_00917 1.67e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
EHMLMMCA_00918 2.4e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EHMLMMCA_00919 2.57e-221 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EHMLMMCA_00920 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
EHMLMMCA_00921 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
EHMLMMCA_00922 2.22e-73 yuzD - - S - - - protein conserved in bacteria
EHMLMMCA_00923 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
EHMLMMCA_00924 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
EHMLMMCA_00925 6.25e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EHMLMMCA_00926 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EHMLMMCA_00927 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
EHMLMMCA_00928 3.98e-115 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EHMLMMCA_00929 8.15e-149 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
EHMLMMCA_00930 6.68e-237 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EHMLMMCA_00932 1.16e-240 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
EHMLMMCA_00933 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
EHMLMMCA_00934 9.78e-47 yuiB - - S - - - Putative membrane protein
EHMLMMCA_00935 1.1e-149 yuiC - - S - - - protein conserved in bacteria
EHMLMMCA_00936 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
EHMLMMCA_00937 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EHMLMMCA_00938 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
EHMLMMCA_00939 4.81e-124 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
EHMLMMCA_00940 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
EHMLMMCA_00941 6.04e-211 eSD - - S ko:K07017 - ko00000 Putative esterase
EHMLMMCA_00942 4.1e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
EHMLMMCA_00943 3.48e-289 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
EHMLMMCA_00944 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
EHMLMMCA_00945 1.1e-228 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
EHMLMMCA_00946 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHMLMMCA_00947 2.02e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
EHMLMMCA_00948 4.88e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
EHMLMMCA_00949 1.64e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
EHMLMMCA_00950 2.96e-292 yukF - - QT - - - Transcriptional regulator
EHMLMMCA_00951 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
EHMLMMCA_00952 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
EHMLMMCA_00953 4.28e-271 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
EHMLMMCA_00954 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
EHMLMMCA_00955 0.0 yueB - - S - - - type VII secretion protein EsaA
EHMLMMCA_00956 1.78e-96 yueC - - S - - - Family of unknown function (DUF5383)
EHMLMMCA_00957 3.53e-170 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHMLMMCA_00958 1.91e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
EHMLMMCA_00959 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
EHMLMMCA_00960 1.68e-85 - - - S - - - Protein of unknown function (DUF2283)
EHMLMMCA_00961 9.11e-243 yueF - - S - - - transporter activity
EHMLMMCA_00962 1.23e-43 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
EHMLMMCA_00963 1.34e-51 yueH - - S - - - YueH-like protein
EHMLMMCA_00964 2.19e-87 - - - S - - - Protein of unknown function (DUF1694)
EHMLMMCA_00965 3.27e-134 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
EHMLMMCA_00966 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EHMLMMCA_00967 2.92e-298 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
EHMLMMCA_00968 8.73e-09 yuzC - - - - - - -
EHMLMMCA_00969 6.29e-10 - - - S - - - DegQ (SacQ) family
EHMLMMCA_00970 8.19e-169 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
EHMLMMCA_00972 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHMLMMCA_00973 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EHMLMMCA_00974 7.81e-83 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
EHMLMMCA_00975 8.49e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
EHMLMMCA_00976 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EHMLMMCA_00977 2.47e-101 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EHMLMMCA_00978 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EHMLMMCA_00979 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EHMLMMCA_00980 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EHMLMMCA_00981 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
EHMLMMCA_00982 1.42e-21 - - - - - - - -
EHMLMMCA_00983 9.73e-310 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
EHMLMMCA_00984 2.43e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
EHMLMMCA_00985 9.08e-237 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
EHMLMMCA_00986 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EHMLMMCA_00987 1.28e-253 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
EHMLMMCA_00988 3.26e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
EHMLMMCA_00989 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
EHMLMMCA_00990 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
EHMLMMCA_00991 3.31e-98 yuxK - - S - - - protein conserved in bacteria
EHMLMMCA_00992 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
EHMLMMCA_00993 8.9e-242 yuxJ - - EGP - - - Major facilitator superfamily
EHMLMMCA_00995 8.49e-150 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
EHMLMMCA_00996 1.44e-90 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
EHMLMMCA_00997 1.06e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHMLMMCA_00998 5.74e-287 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
EHMLMMCA_00999 6.22e-52 yugE - - S - - - Domain of unknown function (DUF1871)
EHMLMMCA_01000 4.03e-200 yugF - - I - - - Hydrolase
EHMLMMCA_01001 6.74e-112 alaR - - K - - - Transcriptional regulator
EHMLMMCA_01002 5.43e-255 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
EHMLMMCA_01003 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
EHMLMMCA_01004 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
EHMLMMCA_01005 8.16e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
EHMLMMCA_01006 3.22e-290 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
EHMLMMCA_01007 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
EHMLMMCA_01009 1.72e-94 yugN - - S - - - YugN-like family
EHMLMMCA_01010 2.06e-232 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
EHMLMMCA_01011 5.01e-69 mstX - - S - - - Membrane-integrating protein Mistic
EHMLMMCA_01012 2.24e-50 - - - - - - - -
EHMLMMCA_01013 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
EHMLMMCA_01014 2.52e-300 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
EHMLMMCA_01015 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
EHMLMMCA_01016 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
EHMLMMCA_01017 1.44e-47 - - - - - - - -
EHMLMMCA_01018 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
EHMLMMCA_01019 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EHMLMMCA_01020 2.29e-295 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EHMLMMCA_01021 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EHMLMMCA_01022 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EHMLMMCA_01024 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
EHMLMMCA_01025 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
EHMLMMCA_01026 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
EHMLMMCA_01027 2.02e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
EHMLMMCA_01028 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
EHMLMMCA_01029 9.11e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
EHMLMMCA_01030 1.73e-252 yubA - - S - - - transporter activity
EHMLMMCA_01031 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EHMLMMCA_01033 3.95e-113 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
EHMLMMCA_01034 0.0 yubD - - P - - - Major Facilitator Superfamily
EHMLMMCA_01035 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EHMLMMCA_01036 3.31e-52 yubF - - S - - - yiaA/B two helix domain
EHMLMMCA_01037 8.78e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
EHMLMMCA_01038 1.5e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
EHMLMMCA_01039 5.83e-118 yuaB - - - - - - -
EHMLMMCA_01040 2.9e-122 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
EHMLMMCA_01041 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EHMLMMCA_01042 2.46e-291 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
EHMLMMCA_01043 8.58e-139 yuaD - - - - - - -
EHMLMMCA_01044 1.95e-109 yuaE - - S - - - DinB superfamily
EHMLMMCA_01045 8e-108 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
EHMLMMCA_01046 9.14e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
EHMLMMCA_01047 3.31e-120 - - - M - - - FR47-like protein
EHMLMMCA_01048 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
EHMLMMCA_01049 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EHMLMMCA_01071 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EHMLMMCA_01072 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EHMLMMCA_01073 5.28e-238 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
EHMLMMCA_01074 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
EHMLMMCA_01075 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
EHMLMMCA_01076 2.81e-101 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
EHMLMMCA_01077 7.75e-262 cotI - - S ko:K06331 - ko00000 Spore coat protein
EHMLMMCA_01078 1.75e-276 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
EHMLMMCA_01079 1.7e-263 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
EHMLMMCA_01081 2.14e-299 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
EHMLMMCA_01082 3.15e-230 ytcB - - M - - - NAD-dependent epimerase dehydratase
EHMLMMCA_01083 2.03e-310 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EHMLMMCA_01084 1.7e-196 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
EHMLMMCA_01085 3.53e-168 yteA - - T - - - COG1734 DnaK suppressor protein
EHMLMMCA_01086 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
EHMLMMCA_01087 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EHMLMMCA_01088 1.1e-193 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
EHMLMMCA_01089 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EHMLMMCA_01090 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
EHMLMMCA_01091 2.88e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
EHMLMMCA_01092 9.26e-218 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
EHMLMMCA_01093 5.03e-178 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
EHMLMMCA_01094 1.5e-295 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
EHMLMMCA_01095 3.76e-191 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
EHMLMMCA_01096 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
EHMLMMCA_01097 2.83e-239 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
EHMLMMCA_01098 7.51e-316 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
EHMLMMCA_01099 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
EHMLMMCA_01100 8.96e-134 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
EHMLMMCA_01101 3.41e-112 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EHMLMMCA_01102 1.95e-94 ytkA - - S - - - YtkA-like
EHMLMMCA_01104 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
EHMLMMCA_01105 1.59e-81 ytkC - - S - - - Bacteriophage holin family
EHMLMMCA_01106 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
EHMLMMCA_01107 1.09e-182 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
EHMLMMCA_01108 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
EHMLMMCA_01109 1.26e-238 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
EHMLMMCA_01110 3.86e-190 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
EHMLMMCA_01111 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
EHMLMMCA_01112 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EHMLMMCA_01113 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EHMLMMCA_01114 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
EHMLMMCA_01115 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
EHMLMMCA_01116 8.35e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EHMLMMCA_01117 2.33e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
EHMLMMCA_01118 2.29e-274 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
EHMLMMCA_01119 1.59e-135 ytqB - - J - - - Putative rRNA methylase
EHMLMMCA_01120 2.35e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
EHMLMMCA_01121 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
EHMLMMCA_01123 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
EHMLMMCA_01124 5.96e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EHMLMMCA_01125 1.72e-192 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
EHMLMMCA_01126 5.96e-180 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
EHMLMMCA_01127 1.02e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EHMLMMCA_01128 6.91e-297 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
EHMLMMCA_01129 1.57e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHMLMMCA_01130 4.53e-239 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
EHMLMMCA_01131 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
EHMLMMCA_01132 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
EHMLMMCA_01133 5.75e-78 yttA - - S - - - Pfam Transposase IS66
EHMLMMCA_01134 2.45e-268 yttB - - EGP - - - Major facilitator superfamily
EHMLMMCA_01135 5.43e-183 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
EHMLMMCA_01136 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
EHMLMMCA_01137 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
EHMLMMCA_01138 1.22e-68 ytwF - - P - - - Sulfurtransferase
EHMLMMCA_01139 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
EHMLMMCA_01140 1.48e-183 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
EHMLMMCA_01141 4.75e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EHMLMMCA_01142 2.58e-312 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
EHMLMMCA_01143 3.75e-243 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
EHMLMMCA_01144 2.66e-218 - - - S - - - Acetyl xylan esterase (AXE1)
EHMLMMCA_01145 3.72e-191 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
EHMLMMCA_01146 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
EHMLMMCA_01147 3.15e-276 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
EHMLMMCA_01148 1.28e-157 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EHMLMMCA_01149 2.64e-243 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EHMLMMCA_01150 4.38e-286 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EHMLMMCA_01151 2.21e-178 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
EHMLMMCA_01152 6.19e-193 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
EHMLMMCA_01153 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
EHMLMMCA_01154 0.0 ytdP - - K - - - Transcriptional regulator
EHMLMMCA_01155 6.24e-219 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
EHMLMMCA_01156 1.88e-275 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
EHMLMMCA_01157 2.76e-93 yteS - - G - - - transport
EHMLMMCA_01158 0.0 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
EHMLMMCA_01159 2.2e-149 yteU - - S - - - Integral membrane protein
EHMLMMCA_01160 2.14e-36 yteV - - S - - - Sporulation protein Cse60
EHMLMMCA_01161 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
EHMLMMCA_01162 6.99e-294 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
EHMLMMCA_01163 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EHMLMMCA_01164 7.43e-170 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
EHMLMMCA_01165 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
EHMLMMCA_01166 5.66e-168 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
EHMLMMCA_01167 3.51e-255 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
EHMLMMCA_01168 7.02e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
EHMLMMCA_01169 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
EHMLMMCA_01170 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
EHMLMMCA_01171 1.23e-129 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EHMLMMCA_01172 4.92e-212 ytlQ - - - - - - -
EHMLMMCA_01173 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
EHMLMMCA_01174 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
EHMLMMCA_01175 3.02e-192 ytmP - - M - - - Phosphotransferase
EHMLMMCA_01176 9.51e-61 ytzH - - S - - - YtzH-like protein
EHMLMMCA_01177 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EHMLMMCA_01178 2.15e-190 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
EHMLMMCA_01179 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
EHMLMMCA_01180 6.75e-67 ytzB - - S - - - small secreted protein
EHMLMMCA_01181 3.71e-261 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
EHMLMMCA_01182 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
EHMLMMCA_01183 3.17e-75 ytpP - - CO - - - Thioredoxin
EHMLMMCA_01184 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
EHMLMMCA_01185 1.2e-138 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EHMLMMCA_01186 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
EHMLMMCA_01187 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
EHMLMMCA_01188 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EHMLMMCA_01189 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
EHMLMMCA_01190 6.39e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
EHMLMMCA_01191 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
EHMLMMCA_01192 4.16e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
EHMLMMCA_01193 6.84e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
EHMLMMCA_01194 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
EHMLMMCA_01195 2.65e-292 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
EHMLMMCA_01196 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
EHMLMMCA_01197 2.43e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
EHMLMMCA_01198 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
EHMLMMCA_01199 1.52e-302 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EHMLMMCA_01201 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EHMLMMCA_01202 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
EHMLMMCA_01203 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
EHMLMMCA_01204 2.94e-142 yttP - - K - - - Transcriptional regulator
EHMLMMCA_01205 1.07e-197 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
EHMLMMCA_01206 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EHMLMMCA_01207 8.23e-305 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
EHMLMMCA_01208 4.75e-267 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
EHMLMMCA_01209 6.26e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHMLMMCA_01210 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
EHMLMMCA_01211 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
EHMLMMCA_01212 0.0 ytcJ - - S - - - amidohydrolase
EHMLMMCA_01213 1.69e-189 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EHMLMMCA_01214 1.38e-229 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
EHMLMMCA_01215 2.36e-111 yteJ - - S - - - RDD family
EHMLMMCA_01216 2.05e-149 ytfI - - S - - - Protein of unknown function (DUF2953)
EHMLMMCA_01217 8.51e-96 ytfJ - - S - - - Sporulation protein YtfJ
EHMLMMCA_01218 1.12e-115 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EHMLMMCA_01219 6.26e-223 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
EHMLMMCA_01220 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EHMLMMCA_01221 8.14e-115 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
EHMLMMCA_01222 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
EHMLMMCA_01223 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
EHMLMMCA_01225 8.04e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHMLMMCA_01226 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
EHMLMMCA_01227 6.8e-221 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
EHMLMMCA_01228 3.42e-129 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
EHMLMMCA_01229 9.11e-195 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
EHMLMMCA_01230 1.57e-191 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
EHMLMMCA_01231 1.66e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EHMLMMCA_01232 6.48e-153 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EHMLMMCA_01233 5.43e-182 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
EHMLMMCA_01234 1.19e-234 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHMLMMCA_01235 1.2e-59 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
EHMLMMCA_01236 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHMLMMCA_01237 2.31e-164 - 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin kinase
EHMLMMCA_01238 1.3e-300 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
EHMLMMCA_01239 6.14e-204 ytnM - - S ko:K07090 - ko00000 membrane transporter protein
EHMLMMCA_01240 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
EHMLMMCA_01241 2.15e-63 ytpI - - S - - - YtpI-like protein
EHMLMMCA_01242 1.24e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
EHMLMMCA_01243 1.15e-39 - - - - - - - -
EHMLMMCA_01244 4.91e-110 ytrI - - - - - - -
EHMLMMCA_01245 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
EHMLMMCA_01246 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
EHMLMMCA_01247 8.53e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
EHMLMMCA_01248 2.17e-208 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EHMLMMCA_01249 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
EHMLMMCA_01250 4.65e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
EHMLMMCA_01251 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
EHMLMMCA_01252 4.68e-82 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
EHMLMMCA_01253 2.24e-244 ytvI - - S - - - sporulation integral membrane protein YtvI
EHMLMMCA_01254 1.56e-93 ytwI - - S - - - membrane
EHMLMMCA_01255 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
EHMLMMCA_01256 9.27e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
EHMLMMCA_01257 1.04e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
EHMLMMCA_01258 1.62e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHMLMMCA_01259 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
EHMLMMCA_01260 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EHMLMMCA_01261 4.05e-202 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EHMLMMCA_01262 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
EHMLMMCA_01263 3.84e-124 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EHMLMMCA_01264 4.54e-205 ytbE - - S - - - reductase
EHMLMMCA_01265 4.57e-254 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
EHMLMMCA_01266 9.85e-88 ytcD - - K - - - Transcriptional regulator
EHMLMMCA_01267 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EHMLMMCA_01268 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EHMLMMCA_01269 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EHMLMMCA_01270 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
EHMLMMCA_01271 1.05e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
EHMLMMCA_01272 9.77e-144 ytxB - - S - - - SNARE associated Golgi protein
EHMLMMCA_01273 3.32e-203 ytxC - - S - - - YtxC-like family
EHMLMMCA_01275 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EHMLMMCA_01276 1.4e-189 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
EHMLMMCA_01277 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHMLMMCA_01278 6.84e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
EHMLMMCA_01279 8.47e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
EHMLMMCA_01280 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
EHMLMMCA_01282 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EHMLMMCA_01283 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
EHMLMMCA_01284 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EHMLMMCA_01285 6.07e-58 ysdA - - S - - - Membrane
EHMLMMCA_01286 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
EHMLMMCA_01287 4.35e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
EHMLMMCA_01288 4.21e-243 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
EHMLMMCA_01289 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
EHMLMMCA_01290 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
EHMLMMCA_01291 6.93e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
EHMLMMCA_01292 4.98e-186 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
EHMLMMCA_01293 9.14e-283 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
EHMLMMCA_01294 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
EHMLMMCA_01295 1.94e-218 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
EHMLMMCA_01296 1.23e-189 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
EHMLMMCA_01297 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
EHMLMMCA_01298 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
EHMLMMCA_01299 1.26e-69 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
EHMLMMCA_01300 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
EHMLMMCA_01301 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
EHMLMMCA_01302 2.25e-263 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
EHMLMMCA_01303 4.37e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
EHMLMMCA_01304 3.13e-171 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHMLMMCA_01305 1.81e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EHMLMMCA_01306 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EHMLMMCA_01307 2.96e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EHMLMMCA_01308 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EHMLMMCA_01309 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
EHMLMMCA_01310 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
EHMLMMCA_01311 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EHMLMMCA_01312 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
EHMLMMCA_01313 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EHMLMMCA_01314 1.21e-130 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
EHMLMMCA_01315 2.2e-176 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
EHMLMMCA_01316 1.28e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
EHMLMMCA_01317 3.02e-228 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
EHMLMMCA_01319 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
EHMLMMCA_01320 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
EHMLMMCA_01321 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EHMLMMCA_01322 4.83e-276 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
EHMLMMCA_01323 2.45e-103 yslB - - S - - - Protein of unknown function (DUF2507)
EHMLMMCA_01324 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
EHMLMMCA_01325 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
EHMLMMCA_01326 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
EHMLMMCA_01327 2.65e-102 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
EHMLMMCA_01328 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
EHMLMMCA_01329 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
EHMLMMCA_01330 5.25e-193 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
EHMLMMCA_01331 3.81e-254 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
EHMLMMCA_01332 3.53e-171 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EHMLMMCA_01333 7.86e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EHMLMMCA_01334 4.05e-119 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
EHMLMMCA_01336 4.1e-184 ysnF - - S - - - protein conserved in bacteria
EHMLMMCA_01337 3.93e-177 - - - N - - - domain, Protein
EHMLMMCA_01338 2.52e-102 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
EHMLMMCA_01340 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
EHMLMMCA_01341 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
EHMLMMCA_01342 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EHMLMMCA_01343 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EHMLMMCA_01344 1.06e-255 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
EHMLMMCA_01345 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EHMLMMCA_01346 7.31e-148 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EHMLMMCA_01347 1.11e-239 ysoA - - H - - - Tetratricopeptide repeat
EHMLMMCA_01348 8.87e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EHMLMMCA_01349 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EHMLMMCA_01350 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
EHMLMMCA_01351 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EHMLMMCA_01352 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
EHMLMMCA_01353 2.36e-116 ysxD - - - - - - -
EHMLMMCA_01354 7.77e-315 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EHMLMMCA_01355 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
EHMLMMCA_01356 7.63e-221 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
EHMLMMCA_01357 6.12e-185 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
EHMLMMCA_01358 3.7e-233 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
EHMLMMCA_01359 1.75e-312 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
EHMLMMCA_01360 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
EHMLMMCA_01361 1.18e-252 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EHMLMMCA_01362 1.53e-35 - - - - - - - -
EHMLMMCA_01363 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EHMLMMCA_01364 1.83e-314 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
EHMLMMCA_01365 9e-109 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
EHMLMMCA_01366 6.07e-211 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
EHMLMMCA_01367 1.73e-132 maf - - D ko:K06287 - ko00000 septum formation protein Maf
EHMLMMCA_01368 8.35e-163 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
EHMLMMCA_01369 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
EHMLMMCA_01370 1.91e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
EHMLMMCA_01371 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
EHMLMMCA_01372 1.75e-157 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
EHMLMMCA_01373 2.91e-186 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
EHMLMMCA_01374 1.5e-186 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
EHMLMMCA_01375 1.25e-206 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
EHMLMMCA_01376 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
EHMLMMCA_01377 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
EHMLMMCA_01378 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
EHMLMMCA_01379 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
EHMLMMCA_01380 1.6e-307 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EHMLMMCA_01381 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
EHMLMMCA_01382 4.99e-209 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
EHMLMMCA_01383 5.86e-122 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
EHMLMMCA_01384 3.35e-290 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
EHMLMMCA_01385 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
EHMLMMCA_01386 5.07e-202 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
EHMLMMCA_01387 7.94e-273 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EHMLMMCA_01388 1.71e-217 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
EHMLMMCA_01389 7.28e-70 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EHMLMMCA_01390 8.63e-165 yebC - - K - - - transcriptional regulatory protein
EHMLMMCA_01391 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
EHMLMMCA_01393 7.31e-67 - - - S - - - Family of unknown function (DUF5412)
EHMLMMCA_01395 2.32e-152 yrzF - - T - - - serine threonine protein kinase
EHMLMMCA_01396 7.93e-248 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
EHMLMMCA_01397 0.0 csbX - - EGP - - - the major facilitator superfamily
EHMLMMCA_01398 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
EHMLMMCA_01399 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EHMLMMCA_01400 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EHMLMMCA_01401 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
EHMLMMCA_01402 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EHMLMMCA_01403 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EHMLMMCA_01404 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
EHMLMMCA_01405 1.07e-98 yrzE - - S - - - Protein of unknown function (DUF3792)
EHMLMMCA_01406 9.01e-147 yrbG - - S - - - membrane
EHMLMMCA_01407 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EHMLMMCA_01408 1.93e-65 yrzD - - S - - - Post-transcriptional regulator
EHMLMMCA_01409 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHMLMMCA_01410 1.87e-113 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
EHMLMMCA_01411 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
EHMLMMCA_01412 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
EHMLMMCA_01413 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EHMLMMCA_01414 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EHMLMMCA_01415 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EHMLMMCA_01416 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
EHMLMMCA_01418 2.57e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
EHMLMMCA_01419 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EHMLMMCA_01420 3.96e-177 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
EHMLMMCA_01421 2.33e-301 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
EHMLMMCA_01422 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
EHMLMMCA_01423 2.66e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
EHMLMMCA_01424 1.19e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EHMLMMCA_01425 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
EHMLMMCA_01426 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EHMLMMCA_01427 1.44e-107 yrrD - - S - - - protein conserved in bacteria
EHMLMMCA_01428 8.4e-42 yrzR - - - - - - -
EHMLMMCA_01429 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
EHMLMMCA_01430 2.65e-139 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EHMLMMCA_01431 3.24e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EHMLMMCA_01432 1.28e-187 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
EHMLMMCA_01433 9.37e-170 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
EHMLMMCA_01434 3.07e-242 yrrI - - S - - - AI-2E family transporter
EHMLMMCA_01435 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EHMLMMCA_01436 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
EHMLMMCA_01437 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EHMLMMCA_01438 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
EHMLMMCA_01439 1.77e-240 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EHMLMMCA_01440 1.4e-154 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
EHMLMMCA_01441 7.67e-223 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
EHMLMMCA_01442 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
EHMLMMCA_01443 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
EHMLMMCA_01444 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EHMLMMCA_01445 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
EHMLMMCA_01446 1.42e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
EHMLMMCA_01447 4.94e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
EHMLMMCA_01448 8.44e-154 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
EHMLMMCA_01449 1.97e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EHMLMMCA_01450 4.07e-217 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
EHMLMMCA_01451 4.95e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
EHMLMMCA_01452 6.93e-49 yrhC - - S - - - YrhC-like protein
EHMLMMCA_01453 4.26e-103 yrhD - - S - - - Protein of unknown function (DUF1641)
EHMLMMCA_01454 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
EHMLMMCA_01455 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
EHMLMMCA_01457 5.62e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
EHMLMMCA_01459 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
EHMLMMCA_01460 7.42e-125 yrhH - - Q - - - methyltransferase
EHMLMMCA_01461 1.31e-134 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
EHMLMMCA_01462 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
EHMLMMCA_01463 7.65e-62 yrhK - - S - - - YrhK-like protein
EHMLMMCA_01464 0.0 oatA - - I - - - Acyltransferase family
EHMLMMCA_01465 7.4e-193 rsiV - - S - - - Protein of unknown function (DUF3298)
EHMLMMCA_01466 9.97e-114 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EHMLMMCA_01467 2.81e-192 yrhO - - K - - - Archaeal transcriptional regulator TrmB
EHMLMMCA_01468 5.63e-137 yrhP - - E - - - LysE type translocator
EHMLMMCA_01469 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
EHMLMMCA_01470 0.0 levR - - K - - - PTS system fructose IIA component
EHMLMMCA_01471 2.18e-96 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
EHMLMMCA_01472 7.63e-107 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
EHMLMMCA_01473 6.11e-168 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
EHMLMMCA_01474 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
EHMLMMCA_01475 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
EHMLMMCA_01476 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
EHMLMMCA_01477 4.81e-253 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
EHMLMMCA_01478 7.79e-16 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
EHMLMMCA_01479 1.5e-66 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
EHMLMMCA_01480 1.46e-65 yraD - - M ko:K06439 - ko00000 Spore coat protein
EHMLMMCA_01481 6.11e-36 yraE - - - ko:K06440 - ko00000 -
EHMLMMCA_01482 9.1e-284 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
EHMLMMCA_01483 9.61e-84 yraF - - M - - - Spore coat protein
EHMLMMCA_01484 1.2e-49 yraG - - - ko:K06440 - ko00000 -
EHMLMMCA_01485 7.44e-84 - - - E - - - Glyoxalase-like domain
EHMLMMCA_01487 2.92e-81 - - - T - - - sh3 domain protein
EHMLMMCA_01488 6.61e-80 - - - T - - - sh3 domain protein
EHMLMMCA_01489 1.64e-198 - - - S - - - Alpha beta hydrolase
EHMLMMCA_01490 6.15e-57 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EHMLMMCA_01491 5.73e-202 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
EHMLMMCA_01492 1.15e-260 yraM - - S - - - PrpF protein
EHMLMMCA_01493 7e-209 yraN - - K - - - Transcriptional regulator
EHMLMMCA_01494 2.16e-285 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
EHMLMMCA_01495 5.96e-240 yrpG - - C - - - Aldo/keto reductase family
EHMLMMCA_01496 3.99e-118 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EHMLMMCA_01497 7.31e-167 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
EHMLMMCA_01499 5.63e-161 yrpD - - S - - - Domain of unknown function, YrpD
EHMLMMCA_01500 2.01e-101 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
EHMLMMCA_01501 2.1e-246 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
EHMLMMCA_01502 2.98e-212 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
EHMLMMCA_01503 2.75e-116 yrdA - - S - - - DinB family
EHMLMMCA_01504 2.99e-71 - - - S - - - Protein of unknown function (DUF2568)
EHMLMMCA_01505 1.37e-126 yrdC - - Q - - - Isochorismatase family
EHMLMMCA_01506 3.39e-293 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EHMLMMCA_01507 2.73e-33 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
EHMLMMCA_01508 8.34e-104 bkdR - - K - - - helix_turn_helix ASNC type
EHMLMMCA_01509 9.34e-176 azlC - - E - - - AzlC protein
EHMLMMCA_01510 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
EHMLMMCA_01511 5.81e-291 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
EHMLMMCA_01512 2.43e-208 - - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
EHMLMMCA_01513 2.05e-86 yodA - - S - - - tautomerase
EHMLMMCA_01514 2.79e-202 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
EHMLMMCA_01515 1.01e-252 trkA - - P ko:K07222 - ko00000 Oxidoreductase
EHMLMMCA_01516 3.3e-202 - - - K - - - Transcriptional regulator
EHMLMMCA_01517 7.28e-218 yrdR - - EG - - - EamA-like transporter family
EHMLMMCA_01518 2.45e-23 - - - S - - - YrzO-like protein
EHMLMMCA_01519 6.45e-301 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
EHMLMMCA_01520 8.79e-108 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
EHMLMMCA_01521 1.87e-269 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
EHMLMMCA_01522 5.9e-193 bltR - - K - - - helix_turn_helix, mercury resistance
EHMLMMCA_01523 2.21e-138 yrkC - - G - - - Cupin domain
EHMLMMCA_01524 4.38e-52 yrkD - - S - - - protein conserved in bacteria
EHMLMMCA_01525 1.96e-108 yrkE - - O - - - DsrE/DsrF/DrsH-like family
EHMLMMCA_01526 4.61e-126 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
EHMLMMCA_01527 4.57e-59 perX - - S - - - DsrE/DsrF-like family
EHMLMMCA_01528 1.98e-261 yrkH - - P - - - Rhodanese Homology Domain
EHMLMMCA_01529 3.2e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
EHMLMMCA_01530 5.31e-155 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
EHMLMMCA_01531 3.13e-104 - - - S - - - Protein of unknown function with HXXEE motif
EHMLMMCA_01532 5.71e-126 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
EHMLMMCA_01533 5.41e-134 yrkN - - K - - - Acetyltransferase (GNAT) family
EHMLMMCA_01534 7.53e-283 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
EHMLMMCA_01535 1.24e-164 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
EHMLMMCA_01536 7.32e-306 yrkQ - - T - - - Histidine kinase
EHMLMMCA_01537 2.15e-90 psiE - - S ko:K13256 - ko00000 Protein PsiE homolog
EHMLMMCA_01538 4.46e-79 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHMLMMCA_01539 1.58e-122 xkdA - - E - - - IrrE N-terminal-like domain
EHMLMMCA_01540 8.73e-132 yqaC - - F - - - adenylate kinase activity
EHMLMMCA_01542 1.25e-74 - - - K - - - sequence-specific DNA binding
EHMLMMCA_01543 3.43e-49 - - - K - - - Helix-turn-helix XRE-family like proteins
EHMLMMCA_01545 9.32e-133 - - - - - - - -
EHMLMMCA_01549 9.38e-229 yqaJ - - L - - - YqaJ-like viral recombinase domain
EHMLMMCA_01550 1.1e-198 recT - - L ko:K07455 - ko00000,ko03400 RecT family
EHMLMMCA_01551 1.92e-158 yqaL - - L - - - DnaD domain protein
EHMLMMCA_01552 4.9e-214 yqaM - - L - - - IstB-like ATP binding protein
EHMLMMCA_01554 1.38e-97 rusA - - L - - - Endodeoxyribonuclease RusA
EHMLMMCA_01555 2.49e-43 yqaO - - S - - - Phage-like element PBSX protein XtrA
EHMLMMCA_01556 7.56e-214 - - - - - - - -
EHMLMMCA_01557 1.58e-105 yqaQ - - L - - - Transposase
EHMLMMCA_01559 2.02e-158 yqaS - - L - - - DNA packaging
EHMLMMCA_01560 0.0 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
EHMLMMCA_01561 0.0 yqbA - - S - - - portal protein
EHMLMMCA_01562 1.73e-217 - - - S - - - Phage Mu protein F like protein
EHMLMMCA_01563 2.13e-149 - - - - - - - -
EHMLMMCA_01564 5.46e-186 yqbD - - L - - - Putative phage serine protease XkdF
EHMLMMCA_01565 9.21e-216 xkdG - - S - - - Phage capsid family
EHMLMMCA_01566 2.47e-68 - - - S - - - YqbF, hypothetical protein domain
EHMLMMCA_01567 7.09e-88 - - - S - - - Protein of unknown function (DUF3199)
EHMLMMCA_01568 7.08e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
EHMLMMCA_01569 7.59e-123 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
EHMLMMCA_01570 3.24e-102 yqbJ - - - - - - -
EHMLMMCA_01571 2.52e-36 - - - - - - - -
EHMLMMCA_01572 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
EHMLMMCA_01573 4.23e-99 xkdM - - S - - - Phage tail tube protein
EHMLMMCA_01575 1.58e-88 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
EHMLMMCA_01576 0.0 xkdO - - L - - - Transglycosylase SLT domain
EHMLMMCA_01577 3.12e-154 xkdP - - S - - - Lysin motif
EHMLMMCA_01578 1.81e-225 xkdQ - - G - - - NLP P60 protein
EHMLMMCA_01579 4.54e-48 xkdR - - S - - - Protein of unknown function (DUF2577)
EHMLMMCA_01580 1.75e-86 xkdS - - S - - - Protein of unknown function (DUF2634)
EHMLMMCA_01581 3.86e-238 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
EHMLMMCA_01582 9.55e-127 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
EHMLMMCA_01583 8.29e-52 - - - - - - - -
EHMLMMCA_01584 1.19e-282 - - - - - - - -
EHMLMMCA_01585 1.01e-73 xkdW - - S - - - XkdW protein
EHMLMMCA_01586 9.34e-33 - - - - - - - -
EHMLMMCA_01587 1.46e-205 xepA - - - - - - -
EHMLMMCA_01588 5.65e-87 - - - S - - - Bacteriophage holin family
EHMLMMCA_01589 8.93e-183 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
EHMLMMCA_01591 5.4e-80 - - - - - - - -
EHMLMMCA_01593 1.37e-135 - - - S ko:K21492 - ko00000,ko02048 Suppressor of fused protein (SUFU)
EHMLMMCA_01594 0.0 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
EHMLMMCA_01597 2.62e-116 - - - S - - - Tetratricopeptide repeat
EHMLMMCA_01598 1.7e-187 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
EHMLMMCA_01599 2.17e-72 arsR - - K ko:K03892 - ko00000,ko03000 ArsR family transcriptional regulator
EHMLMMCA_01600 3.34e-91 cadI 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EHMLMMCA_01601 1.18e-231 arsB - - P ko:K03325 - ko00000,ko02000 Arsenic resistance protein
EHMLMMCA_01602 9.82e-101 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Catalyzes the reduction of arsenate As(V) to arsenite As(III)
EHMLMMCA_01603 0.0 - - - L ko:K06400 - ko00000 Recombinase
EHMLMMCA_01604 1.1e-72 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHMLMMCA_01605 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
EHMLMMCA_01606 9.38e-171 - - - - - - - -
EHMLMMCA_01607 2.66e-217 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
EHMLMMCA_01608 5.41e-134 yqeD - - S - - - SNARE associated Golgi protein
EHMLMMCA_01609 4.44e-172 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
EHMLMMCA_01610 2.61e-181 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
EHMLMMCA_01612 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
EHMLMMCA_01613 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
EHMLMMCA_01614 9.86e-200 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EHMLMMCA_01615 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
EHMLMMCA_01616 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EHMLMMCA_01617 1.13e-131 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
EHMLMMCA_01618 1.14e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EHMLMMCA_01619 1.39e-178 yqeM - - Q - - - Methyltransferase
EHMLMMCA_01620 1.1e-188 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EHMLMMCA_01621 7.77e-137 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
EHMLMMCA_01622 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
EHMLMMCA_01623 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
EHMLMMCA_01624 2.36e-22 - - - S - - - YqzM-like protein
EHMLMMCA_01625 2.35e-243 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
EHMLMMCA_01626 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
EHMLMMCA_01627 3.42e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EHMLMMCA_01628 2.73e-283 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
EHMLMMCA_01629 2.88e-69 yqxA - - S - - - Protein of unknown function (DUF3679)
EHMLMMCA_01630 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EHMLMMCA_01631 1.68e-275 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
EHMLMMCA_01632 1.65e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EHMLMMCA_01633 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EHMLMMCA_01634 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
EHMLMMCA_01635 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EHMLMMCA_01636 4.63e-225 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
EHMLMMCA_01637 1.38e-178 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EHMLMMCA_01638 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
EHMLMMCA_01639 4.02e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
EHMLMMCA_01640 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
EHMLMMCA_01641 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
EHMLMMCA_01642 9.29e-291 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
EHMLMMCA_01643 4.35e-192 yqfA - - S - - - UPF0365 protein
EHMLMMCA_01644 4e-66 yqfB - - - - - - -
EHMLMMCA_01645 2.07e-60 yqfC - - S - - - sporulation protein YqfC
EHMLMMCA_01646 1.04e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
EHMLMMCA_01647 2.47e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
EHMLMMCA_01649 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
EHMLMMCA_01650 8.68e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EHMLMMCA_01651 4.75e-80 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
EHMLMMCA_01652 6.71e-93 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
EHMLMMCA_01653 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EHMLMMCA_01654 5.29e-27 - - - S - - - YqzL-like protein
EHMLMMCA_01655 7.48e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
EHMLMMCA_01656 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
EHMLMMCA_01657 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
EHMLMMCA_01658 3.29e-144 ccpN - - K - - - CBS domain
EHMLMMCA_01659 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
EHMLMMCA_01660 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
EHMLMMCA_01661 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EHMLMMCA_01662 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EHMLMMCA_01663 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
EHMLMMCA_01664 4.66e-148 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
EHMLMMCA_01665 3.77e-269 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EHMLMMCA_01666 4.12e-225 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EHMLMMCA_01667 4.89e-58 yqfQ - - S - - - YqfQ-like protein
EHMLMMCA_01668 5.42e-311 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EHMLMMCA_01669 1.72e-213 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EHMLMMCA_01670 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
EHMLMMCA_01671 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EHMLMMCA_01672 8.59e-107 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
EHMLMMCA_01673 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
EHMLMMCA_01674 2.04e-81 yqfX - - S - - - membrane
EHMLMMCA_01675 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EHMLMMCA_01676 1.16e-62 yqfZ - - M ko:K06417 - ko00000 LysM domain
EHMLMMCA_01677 2.74e-168 yqgB - - S - - - Protein of unknown function (DUF1189)
EHMLMMCA_01678 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
EHMLMMCA_01679 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
EHMLMMCA_01680 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
EHMLMMCA_01681 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
EHMLMMCA_01682 1.51e-204 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
EHMLMMCA_01683 1.43e-202 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
EHMLMMCA_01684 5.26e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
EHMLMMCA_01685 2.8e-189 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EHMLMMCA_01686 2.22e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EHMLMMCA_01687 1.09e-93 yqzC - - S - - - YceG-like family
EHMLMMCA_01688 3.42e-68 yqzD - - - - - - -
EHMLMMCA_01690 1.49e-252 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
EHMLMMCA_01691 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
EHMLMMCA_01692 3.8e-135 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EHMLMMCA_01693 3.38e-14 yqgO - - - - - - -
EHMLMMCA_01694 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
EHMLMMCA_01695 9.15e-45 yqgQ - - S - - - Protein conserved in bacteria
EHMLMMCA_01696 2.81e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
EHMLMMCA_01697 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
EHMLMMCA_01698 3.04e-283 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
EHMLMMCA_01699 5.65e-258 yqgU - - - - - - -
EHMLMMCA_01700 7.34e-66 yqgV - - S - - - Thiamine-binding protein
EHMLMMCA_01701 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
EHMLMMCA_01702 7.54e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
EHMLMMCA_01703 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
EHMLMMCA_01704 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
EHMLMMCA_01706 1.01e-191 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EHMLMMCA_01707 1.42e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
EHMLMMCA_01708 5.89e-231 yqxL - - P - - - Mg2 transporter protein
EHMLMMCA_01710 9.05e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EHMLMMCA_01711 1.76e-218 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
EHMLMMCA_01712 5.33e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
EHMLMMCA_01713 9.7e-94 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
EHMLMMCA_01714 4.35e-79 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
EHMLMMCA_01715 2.9e-46 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
EHMLMMCA_01716 1.88e-57 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
EHMLMMCA_01717 4.9e-37 yqzE - - S - - - YqzE-like protein
EHMLMMCA_01718 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
EHMLMMCA_01719 1.76e-159 yqxM - - - ko:K19433 - ko00000 -
EHMLMMCA_01720 7.4e-98 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
EHMLMMCA_01721 1.49e-180 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
EHMLMMCA_01722 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
EHMLMMCA_01723 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
EHMLMMCA_01724 9.14e-197 yqhG - - S - - - Bacterial protein YqhG of unknown function
EHMLMMCA_01725 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
EHMLMMCA_01726 1.64e-262 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
EHMLMMCA_01727 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EHMLMMCA_01728 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EHMLMMCA_01729 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
EHMLMMCA_01730 9.17e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
EHMLMMCA_01731 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
EHMLMMCA_01732 3.33e-208 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
EHMLMMCA_01733 5.18e-81 yqhP - - - - - - -
EHMLMMCA_01734 5.16e-221 yqhQ - - S - - - Protein of unknown function (DUF1385)
EHMLMMCA_01735 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
EHMLMMCA_01736 1.17e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
EHMLMMCA_01737 6.04e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
EHMLMMCA_01738 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EHMLMMCA_01739 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
EHMLMMCA_01740 8.22e-217 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
EHMLMMCA_01741 5.69e-111 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
EHMLMMCA_01742 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
EHMLMMCA_01743 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
EHMLMMCA_01744 7.65e-257 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
EHMLMMCA_01745 1.28e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
EHMLMMCA_01746 1.26e-147 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
EHMLMMCA_01747 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
EHMLMMCA_01748 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EHMLMMCA_01749 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
EHMLMMCA_01750 1.65e-88 yqhY - - S - - - protein conserved in bacteria
EHMLMMCA_01751 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EHMLMMCA_01752 1.07e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EHMLMMCA_01753 3.55e-312 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EHMLMMCA_01754 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EHMLMMCA_01755 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
EHMLMMCA_01756 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EHMLMMCA_01757 1.77e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
EHMLMMCA_01758 3.75e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
EHMLMMCA_01759 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
EHMLMMCA_01760 2.54e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
EHMLMMCA_01761 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
EHMLMMCA_01763 7.73e-271 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
EHMLMMCA_01764 4.74e-37 - - - - - - - -
EHMLMMCA_01765 3.28e-138 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
EHMLMMCA_01766 7.42e-172 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
EHMLMMCA_01767 3.3e-280 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
EHMLMMCA_01768 1.02e-200 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
EHMLMMCA_01769 1.73e-268 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
EHMLMMCA_01770 6.46e-265 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
EHMLMMCA_01771 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
EHMLMMCA_01772 1.03e-207 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EHMLMMCA_01773 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
EHMLMMCA_01774 0.0 bkdR - - KT - - - Transcriptional regulator
EHMLMMCA_01775 3.02e-199 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
EHMLMMCA_01776 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
EHMLMMCA_01777 3.39e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
EHMLMMCA_01778 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EHMLMMCA_01779 2.24e-237 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EHMLMMCA_01780 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EHMLMMCA_01781 4.4e-287 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EHMLMMCA_01782 4.31e-193 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
EHMLMMCA_01783 3.09e-267 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
EHMLMMCA_01784 1.72e-213 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EHMLMMCA_01785 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
EHMLMMCA_01786 2.89e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
EHMLMMCA_01787 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
EHMLMMCA_01788 7.39e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
EHMLMMCA_01789 1.09e-224 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
EHMLMMCA_01790 9.84e-128 yqjB - - S - - - protein conserved in bacteria
EHMLMMCA_01792 7.17e-99 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
EHMLMMCA_01793 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
EHMLMMCA_01794 1.76e-257 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
EHMLMMCA_01795 2.82e-180 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
EHMLMMCA_01796 3.36e-184 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EHMLMMCA_01797 1.77e-32 yqzJ - - - - - - -
EHMLMMCA_01798 7.8e-301 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EHMLMMCA_01799 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EHMLMMCA_01800 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EHMLMMCA_01801 3.12e-221 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EHMLMMCA_01802 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
EHMLMMCA_01803 3.86e-188 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EHMLMMCA_01804 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
EHMLMMCA_01805 0.0 rocB - - E - - - arginine degradation protein
EHMLMMCA_01806 2.67e-187 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EHMLMMCA_01807 2.69e-228 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
EHMLMMCA_01808 1.62e-183 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
EHMLMMCA_01809 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
EHMLMMCA_01810 2.69e-228 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
EHMLMMCA_01811 1.28e-93 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EHMLMMCA_01813 2.28e-286 yqjV - - G - - - Major Facilitator Superfamily
EHMLMMCA_01815 5.49e-302 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EHMLMMCA_01816 3.23e-66 yqiX - - S - - - YolD-like protein
EHMLMMCA_01817 1.29e-111 yqjY - - K ko:K06977 - ko00000 acetyltransferase
EHMLMMCA_01818 2.25e-78 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
EHMLMMCA_01819 2.28e-248 yqkA - - K - - - GrpB protein
EHMLMMCA_01820 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
EHMLMMCA_01821 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
EHMLMMCA_01822 1.38e-223 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
EHMLMMCA_01823 6.61e-26 yqkE - - S - - - Protein of unknown function (DUF3886)
EHMLMMCA_01824 5.13e-215 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
EHMLMMCA_01825 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
EHMLMMCA_01826 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
EHMLMMCA_01827 1.98e-278 yqxK - - L - - - DNA helicase
EHMLMMCA_01828 1.29e-76 ansR - - K - - - Transcriptional regulator
EHMLMMCA_01829 3.58e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
EHMLMMCA_01830 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
EHMLMMCA_01831 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
EHMLMMCA_01832 5.62e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
EHMLMMCA_01833 8.52e-41 yqkK - - - - - - -
EHMLMMCA_01834 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
EHMLMMCA_01835 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
EHMLMMCA_01836 2.25e-49 - - - S - - - Protein of unknown function (DUF4227)
EHMLMMCA_01837 1.59e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
EHMLMMCA_01838 2.77e-293 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
EHMLMMCA_01839 3.27e-189 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EHMLMMCA_01840 2.89e-272 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
EHMLMMCA_01841 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
EHMLMMCA_01842 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
EHMLMMCA_01843 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHMLMMCA_01844 1.15e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
EHMLMMCA_01845 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
EHMLMMCA_01846 5.52e-101 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
EHMLMMCA_01847 6.02e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
EHMLMMCA_01848 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
EHMLMMCA_01849 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
EHMLMMCA_01850 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
EHMLMMCA_01851 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EHMLMMCA_01852 8.93e-192 ypuA - - S - - - Secreted protein
EHMLMMCA_01853 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EHMLMMCA_01856 5.49e-17 - - - S - - - SNARE associated Golgi protein
EHMLMMCA_01857 7.41e-45 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
EHMLMMCA_01858 1.18e-132 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
EHMLMMCA_01859 5.98e-72 ypuD - - - - - - -
EHMLMMCA_01860 8.41e-260 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EHMLMMCA_01861 7.16e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
EHMLMMCA_01862 1.27e-291 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EHMLMMCA_01863 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
EHMLMMCA_01864 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EHMLMMCA_01865 1.19e-118 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
EHMLMMCA_01866 3.82e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EHMLMMCA_01867 2e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EHMLMMCA_01868 2.92e-126 ypuI - - S - - - Protein of unknown function (DUF3907)
EHMLMMCA_01869 2.28e-270 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
EHMLMMCA_01870 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
EHMLMMCA_01871 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
EHMLMMCA_01872 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
EHMLMMCA_01873 1.5e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
EHMLMMCA_01874 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
EHMLMMCA_01875 1.34e-278 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
EHMLMMCA_01876 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHMLMMCA_01877 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHMLMMCA_01878 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EHMLMMCA_01879 1.49e-254 rsiX - - - - - - -
EHMLMMCA_01880 1.67e-174 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
EHMLMMCA_01881 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHMLMMCA_01882 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EHMLMMCA_01883 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
EHMLMMCA_01884 5.67e-258 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
EHMLMMCA_01885 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
EHMLMMCA_01886 3.55e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
EHMLMMCA_01887 1.37e-141 ypbE - - M - - - Lysin motif
EHMLMMCA_01888 1.42e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
EHMLMMCA_01889 4.33e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
EHMLMMCA_01890 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
EHMLMMCA_01891 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
EHMLMMCA_01892 6.04e-223 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
EHMLMMCA_01893 1.76e-153 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
EHMLMMCA_01894 1.15e-206 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
EHMLMMCA_01895 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
EHMLMMCA_01896 1.09e-142 ypfA - - M - - - Flagellar protein YcgR
EHMLMMCA_01897 1.74e-32 - - - S - - - Family of unknown function (DUF5359)
EHMLMMCA_01898 5.8e-146 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
EHMLMMCA_01899 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
EHMLMMCA_01900 1.33e-234 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EHMLMMCA_01901 1.13e-11 - - - S - - - YpzI-like protein
EHMLMMCA_01902 3.18e-133 yphA - - - - - - -
EHMLMMCA_01903 1.77e-206 yphB - - S ko:K05739 - ko00000 YIEGIA protein
EHMLMMCA_01904 2.06e-38 ypzH - - - - - - -
EHMLMMCA_01905 5.72e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
EHMLMMCA_01906 9.24e-228 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
EHMLMMCA_01907 3.51e-27 yphE - - S - - - Protein of unknown function (DUF2768)
EHMLMMCA_01908 9.07e-178 yphF - - - - - - -
EHMLMMCA_01909 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EHMLMMCA_01910 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EHMLMMCA_01911 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
EHMLMMCA_01912 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
EHMLMMCA_01913 7.17e-177 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
EHMLMMCA_01914 1.34e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
EHMLMMCA_01915 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
EHMLMMCA_01916 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
EHMLMMCA_01917 3.03e-182 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
EHMLMMCA_01918 2.91e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EHMLMMCA_01919 4.7e-262 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EHMLMMCA_01920 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
EHMLMMCA_01921 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EHMLMMCA_01922 6.08e-230 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EHMLMMCA_01923 1.2e-144 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
EHMLMMCA_01924 2.71e-151 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
EHMLMMCA_01925 3.8e-294 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EHMLMMCA_01926 5.43e-186 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
EHMLMMCA_01927 4.5e-259 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EHMLMMCA_01928 1.71e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
EHMLMMCA_01929 1.35e-299 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EHMLMMCA_01930 8.74e-298 ypiA - - S - - - COG0457 FOG TPR repeat
EHMLMMCA_01931 1.83e-129 ypiB - - S - - - Belongs to the UPF0302 family
EHMLMMCA_01932 3.75e-98 ypiF - - S - - - Protein of unknown function (DUF2487)
EHMLMMCA_01933 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
EHMLMMCA_01934 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
EHMLMMCA_01935 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
EHMLMMCA_01936 2.82e-126 ypjA - - S - - - membrane
EHMLMMCA_01937 2.79e-182 ypjB - - S - - - sporulation protein
EHMLMMCA_01938 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EHMLMMCA_01939 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
EHMLMMCA_01940 2.4e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EHMLMMCA_01941 4.19e-92 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
EHMLMMCA_01942 1.56e-165 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
EHMLMMCA_01943 4.94e-267 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
EHMLMMCA_01944 3.04e-278 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EHMLMMCA_01945 4.87e-234 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EHMLMMCA_01946 4.85e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
EHMLMMCA_01947 1.34e-200 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EHMLMMCA_01948 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EHMLMMCA_01949 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
EHMLMMCA_01950 6.21e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
EHMLMMCA_01951 2.66e-102 ypmB - - S - - - protein conserved in bacteria
EHMLMMCA_01952 1.25e-284 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
EHMLMMCA_01953 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
EHMLMMCA_01954 6.62e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
EHMLMMCA_01955 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EHMLMMCA_01956 1.43e-121 ypoC - - - - - - -
EHMLMMCA_01957 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
EHMLMMCA_01958 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EHMLMMCA_01959 3.44e-236 yppC - - S - - - Protein of unknown function (DUF2515)
EHMLMMCA_01962 7.14e-11 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
EHMLMMCA_01963 9.21e-11 - - - S - - - YppF-like protein
EHMLMMCA_01964 8.72e-68 yppG - - S - - - YppG-like protein
EHMLMMCA_01965 4.33e-95 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
EHMLMMCA_01966 6.36e-111 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
EHMLMMCA_01967 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
EHMLMMCA_01968 9.82e-299 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
EHMLMMCA_01969 1.19e-128 ypsA - - S - - - Belongs to the UPF0398 family
EHMLMMCA_01970 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EHMLMMCA_01971 1.11e-283 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
EHMLMMCA_01973 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
EHMLMMCA_01974 1.68e-178 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHMLMMCA_01975 1.03e-203 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
EHMLMMCA_01976 2.14e-235 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
EHMLMMCA_01977 1.15e-236 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
EHMLMMCA_01978 1.47e-132 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
EHMLMMCA_01979 6.77e-223 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
EHMLMMCA_01980 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EHMLMMCA_01981 8.16e-129 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EHMLMMCA_01982 1.67e-203 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
EHMLMMCA_01983 2.28e-69 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
EHMLMMCA_01984 4.55e-266 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
EHMLMMCA_01985 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
EHMLMMCA_01986 0.0 ypbR - - S - - - Dynamin family
EHMLMMCA_01987 4.07e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
EHMLMMCA_01988 1.08e-11 - - - - - - - -
EHMLMMCA_01989 2.26e-213 ypcP - - L - - - 5'3' exonuclease
EHMLMMCA_01990 5.23e-05 - - - - ko:K06429 - ko00000 -
EHMLMMCA_01991 7.64e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
EHMLMMCA_01992 3.27e-136 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EHMLMMCA_01993 9.17e-173 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
EHMLMMCA_01994 1.54e-37 ypeQ - - S - - - Zinc-finger
EHMLMMCA_01995 6.1e-40 - - - S - - - Protein of unknown function (DUF2564)
EHMLMMCA_01996 1.17e-22 degR - - - - - - -
EHMLMMCA_01997 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
EHMLMMCA_01998 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
EHMLMMCA_02000 1.28e-226 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EHMLMMCA_02001 2.21e-114 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
EHMLMMCA_02002 1.34e-137 yagB - - S ko:K06950 - ko00000 phosphohydrolase
EHMLMMCA_02003 3.46e-205 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
EHMLMMCA_02004 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
EHMLMMCA_02005 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
EHMLMMCA_02006 3.41e-184 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
EHMLMMCA_02007 1.16e-146 ypjP - - S - - - YpjP-like protein
EHMLMMCA_02008 8.91e-121 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
EHMLMMCA_02009 9.52e-199 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EHMLMMCA_02010 9.58e-122 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EHMLMMCA_02011 8.12e-144 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
EHMLMMCA_02012 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
EHMLMMCA_02013 1.4e-236 yplP - - K - - - Transcriptional regulator
EHMLMMCA_02014 1.04e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EHMLMMCA_02015 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
EHMLMMCA_02016 1.6e-139 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
EHMLMMCA_02017 1.49e-177 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
EHMLMMCA_02018 1.6e-127 ypmS - - S - - - protein conserved in bacteria
EHMLMMCA_02019 2.13e-40 ypmT - - S - - - Uncharacterized ympT
EHMLMMCA_02020 2.86e-289 mepA - - V - - - MATE efflux family protein
EHMLMMCA_02021 4.14e-94 ypoP - - K - - - transcriptional
EHMLMMCA_02022 9.83e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHMLMMCA_02023 7.13e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
EHMLMMCA_02024 1.66e-157 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
EHMLMMCA_02025 6.91e-281 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
EHMLMMCA_02026 1.2e-239 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
EHMLMMCA_02027 5.57e-86 cgeA - - - ko:K06319 - ko00000 -
EHMLMMCA_02028 1.76e-58 cgeC - - - ko:K06321 - ko00000 -
EHMLMMCA_02029 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
EHMLMMCA_02030 1.97e-184 yiiD - - K ko:K06323 - ko00000 acetyltransferase
EHMLMMCA_02032 9.36e-317 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EHMLMMCA_02033 3.41e-161 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EHMLMMCA_02034 7.76e-152 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
EHMLMMCA_02035 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
EHMLMMCA_02036 2.61e-197 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
EHMLMMCA_02037 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
EHMLMMCA_02038 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
EHMLMMCA_02039 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
EHMLMMCA_02040 3.84e-161 yodN - - - - - - -
EHMLMMCA_02042 5.18e-34 yozD - - S - - - YozD-like protein
EHMLMMCA_02043 1.35e-136 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
EHMLMMCA_02044 1.17e-71 yodL - - S - - - YodL-like
EHMLMMCA_02045 2.08e-12 - - - - - - - -
EHMLMMCA_02046 6.86e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
EHMLMMCA_02047 1.33e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
EHMLMMCA_02048 2.93e-42 yodI - - - - - - -
EHMLMMCA_02049 3.03e-166 yodH - - Q - - - Methyltransferase
EHMLMMCA_02050 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
EHMLMMCA_02051 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHMLMMCA_02052 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
EHMLMMCA_02053 1.32e-220 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
EHMLMMCA_02054 1.31e-146 yahD - - S ko:K06999 - ko00000 Carboxylesterase
EHMLMMCA_02055 6.44e-139 yodC - - C - - - nitroreductase
EHMLMMCA_02056 2.63e-73 yodB - - K - - - transcriptional
EHMLMMCA_02057 5.64e-84 iolK - - S - - - tautomerase
EHMLMMCA_02058 9.24e-290 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
EHMLMMCA_02059 1.95e-14 - - - - - - - -
EHMLMMCA_02060 1.17e-102 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
EHMLMMCA_02061 1.92e-206 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
EHMLMMCA_02062 1.85e-58 - - - - - - - -
EHMLMMCA_02063 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
EHMLMMCA_02064 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
EHMLMMCA_02065 1.01e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EHMLMMCA_02066 3.41e-312 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
EHMLMMCA_02068 4.31e-141 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EHMLMMCA_02069 1.13e-293 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
EHMLMMCA_02070 6.16e-266 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
EHMLMMCA_02071 8.54e-141 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EHMLMMCA_02072 1.33e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
EHMLMMCA_02073 0.0 yojO - - P - - - Von Willebrand factor
EHMLMMCA_02074 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
EHMLMMCA_02075 5.23e-264 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
EHMLMMCA_02076 2.23e-212 yocS - - S ko:K03453 - ko00000 -transporter
EHMLMMCA_02077 3.57e-299 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
EHMLMMCA_02078 1.36e-211 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
EHMLMMCA_02079 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
EHMLMMCA_02080 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EHMLMMCA_02081 1.91e-42 yozC - - - - - - -
EHMLMMCA_02083 2.17e-74 yozO - - S - - - Bacterial PH domain
EHMLMMCA_02084 1.83e-49 yocN - - - - - - -
EHMLMMCA_02085 2.94e-55 yozN - - - - - - -
EHMLMMCA_02086 6.6e-115 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
EHMLMMCA_02087 5.79e-43 - - - - - - - -
EHMLMMCA_02088 4.29e-70 yocL - - - - - - -
EHMLMMCA_02089 1.42e-107 yocK - - T - - - general stress protein
EHMLMMCA_02090 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EHMLMMCA_02091 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
EHMLMMCA_02092 2.89e-175 yocH - - M - - - COG1388 FOG LysM repeat
EHMLMMCA_02093 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EHMLMMCA_02094 3.51e-252 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHMLMMCA_02095 3.28e-257 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
EHMLMMCA_02096 2.73e-240 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
EHMLMMCA_02097 1.08e-121 yocC - - - - - - -
EHMLMMCA_02098 2.49e-183 - - - - - - - -
EHMLMMCA_02099 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
EHMLMMCA_02100 2.12e-155 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EHMLMMCA_02101 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
EHMLMMCA_02102 3.01e-120 yobW - - - - - - -
EHMLMMCA_02103 1.33e-225 yobV - - K - - - WYL domain
EHMLMMCA_02104 6.32e-114 - - - K - - - Bacterial transcription activator, effector binding domain
EHMLMMCA_02105 7.76e-169 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
EHMLMMCA_02106 3.09e-127 yobS - - K - - - Transcriptional regulator
EHMLMMCA_02107 5.06e-181 - - - J - - - FR47-like protein
EHMLMMCA_02108 4.48e-172 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
EHMLMMCA_02109 1.82e-71 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
EHMLMMCA_02110 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
EHMLMMCA_02111 1.14e-131 yokH - - G - - - SMI1 / KNR4 family
EHMLMMCA_02112 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
EHMLMMCA_02113 2.24e-110 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
EHMLMMCA_02114 1.09e-134 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
EHMLMMCA_02115 0.0 aga 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Alpha-galactosidase
EHMLMMCA_02116 1.33e-141 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EHMLMMCA_02117 3.76e-129 - - - P ko:K02026,ko:K10242 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
EHMLMMCA_02118 5.09e-53 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
EHMLMMCA_02120 1.23e-272 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 1
EHMLMMCA_02121 3.14e-167 - - - K - - - Bacterial regulatory proteins, lacI family
EHMLMMCA_02122 1.04e-219 - 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
EHMLMMCA_02123 2.71e-29 dinB2 - - L ko:K03502 - ko00000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EHMLMMCA_02124 1.48e-30 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
EHMLMMCA_02125 9.27e-86 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
EHMLMMCA_02126 1.08e-73 - - - K - - - Helix-turn-helix
EHMLMMCA_02127 6.27e-51 - - - S - - - TM2 domain
EHMLMMCA_02129 1.3e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
EHMLMMCA_02130 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
EHMLMMCA_02133 1.72e-213 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
EHMLMMCA_02134 5.08e-149 lin0465 - - S - - - DJ-1/PfpI family
EHMLMMCA_02135 1.38e-102 yoaW - - - - - - -
EHMLMMCA_02136 4.32e-200 yoaV - - EG - - - EamA-like transporter family
EHMLMMCA_02137 7.78e-202 yoaU - - K - - - LysR substrate binding domain
EHMLMMCA_02138 5.46e-189 yoaT - - S - - - Protein of unknown function (DUF817)
EHMLMMCA_02139 7.38e-50 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
EHMLMMCA_02140 3.22e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
EHMLMMCA_02141 1.04e-217 yoaR - - V - - - vancomycin resistance protein
EHMLMMCA_02142 6e-110 - - - - - - - -
EHMLMMCA_02144 1.49e-87 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
EHMLMMCA_02145 3.71e-185 yoaP - - K - - - YoaP-like
EHMLMMCA_02147 1.21e-290 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
EHMLMMCA_02150 2.07e-170 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
EHMLMMCA_02151 2.38e-251 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
EHMLMMCA_02152 1.79e-145 yoaK - - S - - - Membrane
EHMLMMCA_02153 5.06e-169 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
EHMLMMCA_02154 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
EHMLMMCA_02155 3.58e-314 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
EHMLMMCA_02156 2.99e-55 - - - S - - - Protein of unknown function (DUF4025)
EHMLMMCA_02157 1.2e-18 - - - - - - - -
EHMLMMCA_02159 7.24e-45 yoaF - - - - - - -
EHMLMMCA_02160 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EHMLMMCA_02161 1.37e-233 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHMLMMCA_02162 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
EHMLMMCA_02163 7.16e-297 yoaB - - EGP - - - the major facilitator superfamily
EHMLMMCA_02164 2.75e-160 - 3.1.1.3 - I ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 Lipase (class 3)
EHMLMMCA_02165 1.7e-300 - - - S - - - Arylsulfotransferase (ASST)
EHMLMMCA_02166 1.14e-113 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EHMLMMCA_02167 5.51e-168 yoxB - - - - - - -
EHMLMMCA_02168 9.05e-52 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
EHMLMMCA_02169 6.25e-157 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
EHMLMMCA_02170 5.59e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
EHMLMMCA_02171 2.24e-184 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EHMLMMCA_02172 8.13e-263 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EHMLMMCA_02173 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
EHMLMMCA_02174 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
EHMLMMCA_02175 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
EHMLMMCA_02176 4.18e-237 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
EHMLMMCA_02177 4.16e-199 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
EHMLMMCA_02178 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
EHMLMMCA_02179 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
EHMLMMCA_02180 1.14e-124 - - - L - - - Integrase
EHMLMMCA_02182 2.91e-127 yoeB - - S - - - IseA DL-endopeptidase inhibitor
EHMLMMCA_02183 8.05e-312 yoeA - - V - - - MATE efflux family protein
EHMLMMCA_02184 4.05e-242 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
EHMLMMCA_02185 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
EHMLMMCA_02186 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHMLMMCA_02187 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHMLMMCA_02188 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHMLMMCA_02189 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHMLMMCA_02190 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
EHMLMMCA_02191 2.48e-83 yngL - - S - - - Protein of unknown function (DUF1360)
EHMLMMCA_02192 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
EHMLMMCA_02193 2.97e-07 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
EHMLMMCA_02194 1.26e-266 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
EHMLMMCA_02195 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EHMLMMCA_02196 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
EHMLMMCA_02197 1.23e-43 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
EHMLMMCA_02198 6.73e-212 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
EHMLMMCA_02199 4.25e-175 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
EHMLMMCA_02200 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
EHMLMMCA_02201 9e-297 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
EHMLMMCA_02202 2.01e-134 yngC - - S - - - membrane-associated protein
EHMLMMCA_02203 4.54e-209 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
EHMLMMCA_02204 2.45e-103 yngA - - S - - - membrane
EHMLMMCA_02205 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
EHMLMMCA_02206 9.85e-317 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
EHMLMMCA_02208 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
EHMLMMCA_02209 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
EHMLMMCA_02210 1.06e-75 ynfC - - - - - - -
EHMLMMCA_02211 1.82e-18 - - - - - - - -
EHMLMMCA_02212 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EHMLMMCA_02213 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EHMLMMCA_02214 7e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
EHMLMMCA_02215 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EHMLMMCA_02216 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
EHMLMMCA_02217 1.63e-71 yneQ - - - - - - -
EHMLMMCA_02218 1.4e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
EHMLMMCA_02219 1.9e-47 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
EHMLMMCA_02221 9.26e-10 - - - S - - - Fur-regulated basic protein B
EHMLMMCA_02222 3.74e-120 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EHMLMMCA_02223 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EHMLMMCA_02224 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
EHMLMMCA_02225 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
EHMLMMCA_02226 5.77e-85 cotM - - O ko:K06335 - ko00000 Spore coat protein
EHMLMMCA_02227 3.97e-97 yneK - - S - - - Protein of unknown function (DUF2621)
EHMLMMCA_02228 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
EHMLMMCA_02229 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
EHMLMMCA_02230 1.68e-164 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
EHMLMMCA_02231 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
EHMLMMCA_02232 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
EHMLMMCA_02233 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
EHMLMMCA_02234 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EHMLMMCA_02235 1.15e-43 ynzC - - S - - - UPF0291 protein
EHMLMMCA_02236 2.29e-144 yneB - - L - - - resolvase
EHMLMMCA_02237 2.44e-64 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
EHMLMMCA_02238 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EHMLMMCA_02239 4.44e-104 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
EHMLMMCA_02240 2.67e-96 yndM - - S - - - Protein of unknown function (DUF2512)
EHMLMMCA_02241 3.26e-175 yndL - - S - - - Replication protein
EHMLMMCA_02243 0.0 yndJ - - S - - - YndJ-like protein
EHMLMMCA_02244 1.71e-149 - - - S - - - Domain of unknown function (DUF4166)
EHMLMMCA_02245 3.58e-196 yndG - - S - - - DoxX-like family
EHMLMMCA_02246 9.64e-290 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
EHMLMMCA_02247 1.95e-250 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
EHMLMMCA_02248 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
EHMLMMCA_02251 3.12e-104 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
EHMLMMCA_02252 8.92e-96 - - - - - - - -
EHMLMMCA_02253 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
EHMLMMCA_02256 2.11e-170 - - - S - - - Domain of unknown function, YrpD
EHMLMMCA_02258 3.91e-210 - - - S - - - Thymidylate synthase
EHMLMMCA_02261 7.54e-22 - - - - - - - -
EHMLMMCA_02262 3.01e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
EHMLMMCA_02263 9.48e-108 - - - S - - - Protein of unknown function (DUF2691)
EHMLMMCA_02264 1.77e-280 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHMLMMCA_02265 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EHMLMMCA_02266 2.51e-145 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
EHMLMMCA_02267 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
EHMLMMCA_02268 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
EHMLMMCA_02269 8.66e-276 xylR - - GK - - - ROK family
EHMLMMCA_02270 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
EHMLMMCA_02271 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
EHMLMMCA_02272 1.38e-105 - - - E - - - phosphoribosylanthranilate isomerase activity
EHMLMMCA_02275 4.46e-142 - - - S - - - Domain of unknown function (DUF3885)
EHMLMMCA_02276 3.39e-31 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
EHMLMMCA_02277 3.35e-11 ywlA - - S - - - Uncharacterised protein family (UPF0715)
EHMLMMCA_02278 2.44e-90 - - - S - - - CAAX protease self-immunity
EHMLMMCA_02279 3.95e-124 ynaD - - J - - - Acetyltransferase (GNAT) domain
EHMLMMCA_02281 7.73e-275 - - - H - - - N-terminal domain of galactosyltransferase
EHMLMMCA_02282 1.29e-202 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
EHMLMMCA_02283 2.22e-47 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
EHMLMMCA_02284 1.79e-74 - - - S - - - Bacteriophage holin family
EHMLMMCA_02285 1.92e-120 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
EHMLMMCA_02286 8.33e-77 - - - L - - - Belongs to the 'phage' integrase family
EHMLMMCA_02287 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
EHMLMMCA_02288 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
EHMLMMCA_02289 1.67e-310 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
EHMLMMCA_02290 4.47e-294 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EHMLMMCA_02291 9.33e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
EHMLMMCA_02292 5.74e-150 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
EHMLMMCA_02293 2.24e-141 - - - - - - - -
EHMLMMCA_02294 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EHMLMMCA_02295 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EHMLMMCA_02296 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
EHMLMMCA_02297 1.2e-30 ymzA - - - - - - -
EHMLMMCA_02298 1.63e-31 - - - - - - - -
EHMLMMCA_02299 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
EHMLMMCA_02300 1.38e-223 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EHMLMMCA_02301 5.41e-76 ymaF - - S - - - YmaF family
EHMLMMCA_02303 1.21e-67 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
EHMLMMCA_02304 3.16e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
EHMLMMCA_02305 1.03e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
EHMLMMCA_02306 3.96e-163 ymaC - - S - - - Replication protein
EHMLMMCA_02308 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
EHMLMMCA_02309 2.67e-207 - - - S - - - Metallo-beta-lactamase superfamily
EHMLMMCA_02310 8.03e-81 ymzB - - - - - - -
EHMLMMCA_02311 7.99e-294 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EHMLMMCA_02312 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
EHMLMMCA_02313 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
EHMLMMCA_02314 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
EHMLMMCA_02315 0.0 - - - Q ko:K13612 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EHMLMMCA_02316 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
EHMLMMCA_02317 4.29e-174 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
EHMLMMCA_02318 1.44e-183 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
EHMLMMCA_02319 1.13e-312 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
EHMLMMCA_02320 4.36e-303 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EHMLMMCA_02321 5.46e-51 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
EHMLMMCA_02322 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
EHMLMMCA_02323 1.64e-236 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
EHMLMMCA_02325 1.78e-206 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
EHMLMMCA_02326 4.02e-167 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
EHMLMMCA_02327 2.94e-141 pksA - - K - - - Transcriptional regulator
EHMLMMCA_02328 1.38e-127 ymcC - - S - - - Membrane
EHMLMMCA_02329 6.68e-92 - - - S - - - Regulatory protein YrvL
EHMLMMCA_02330 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EHMLMMCA_02331 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EHMLMMCA_02332 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
EHMLMMCA_02333 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
EHMLMMCA_02334 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EHMLMMCA_02335 4.15e-278 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
EHMLMMCA_02336 8.31e-253 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
EHMLMMCA_02337 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
EHMLMMCA_02338 6.18e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
EHMLMMCA_02339 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
EHMLMMCA_02340 8.43e-282 pbpX - - V - - - Beta-lactamase
EHMLMMCA_02341 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EHMLMMCA_02342 3.71e-300 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
EHMLMMCA_02343 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EHMLMMCA_02344 3.05e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
EHMLMMCA_02345 5.56e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
EHMLMMCA_02346 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
EHMLMMCA_02347 6.33e-168 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
EHMLMMCA_02348 2.37e-309 ymfH - - S - - - zinc protease
EHMLMMCA_02349 9.47e-299 albE - - S - - - Peptidase M16
EHMLMMCA_02350 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EHMLMMCA_02351 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
EHMLMMCA_02352 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
EHMLMMCA_02353 4.94e-44 - - - S - - - YlzJ-like protein
EHMLMMCA_02354 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
EHMLMMCA_02355 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EHMLMMCA_02356 1.57e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EHMLMMCA_02357 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
EHMLMMCA_02358 1.66e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EHMLMMCA_02359 9.94e-142 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
EHMLMMCA_02360 5.3e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
EHMLMMCA_02361 1.53e-56 ymxH - - S - - - YlmC YmxH family
EHMLMMCA_02362 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
EHMLMMCA_02363 2.06e-232 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
EHMLMMCA_02364 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
EHMLMMCA_02365 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EHMLMMCA_02366 1.1e-230 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
EHMLMMCA_02367 6.04e-220 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EHMLMMCA_02368 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EHMLMMCA_02369 7.83e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
EHMLMMCA_02370 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EHMLMMCA_02371 6.16e-63 ylxQ - - J - - - ribosomal protein
EHMLMMCA_02372 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
EHMLMMCA_02373 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
EHMLMMCA_02374 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
EHMLMMCA_02375 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EHMLMMCA_02376 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EHMLMMCA_02377 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
EHMLMMCA_02378 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
EHMLMMCA_02379 5.77e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
EHMLMMCA_02380 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EHMLMMCA_02381 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EHMLMMCA_02382 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
EHMLMMCA_02383 8.06e-201 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EHMLMMCA_02384 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
EHMLMMCA_02385 6.62e-99 ylxL - - - - - - -
EHMLMMCA_02386 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHMLMMCA_02387 1.36e-111 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
EHMLMMCA_02388 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
EHMLMMCA_02389 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
EHMLMMCA_02390 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
EHMLMMCA_02391 1.81e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
EHMLMMCA_02392 1.09e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
EHMLMMCA_02393 9.37e-255 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
EHMLMMCA_02394 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EHMLMMCA_02395 2.74e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EHMLMMCA_02396 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
EHMLMMCA_02397 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
EHMLMMCA_02398 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
EHMLMMCA_02399 7.87e-137 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
EHMLMMCA_02400 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
EHMLMMCA_02401 7.96e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EHMLMMCA_02402 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
EHMLMMCA_02403 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
EHMLMMCA_02404 1.09e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
EHMLMMCA_02405 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
EHMLMMCA_02406 2.27e-309 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
EHMLMMCA_02407 1.02e-83 ylxF - - S - - - MgtE intracellular N domain
EHMLMMCA_02408 7.27e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
EHMLMMCA_02409 3.5e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
EHMLMMCA_02410 1.92e-144 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
EHMLMMCA_02411 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
EHMLMMCA_02412 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
EHMLMMCA_02413 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
EHMLMMCA_02414 7.54e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
EHMLMMCA_02415 1.62e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
EHMLMMCA_02416 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EHMLMMCA_02417 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EHMLMMCA_02418 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EHMLMMCA_02419 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
EHMLMMCA_02420 5.45e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EHMLMMCA_02421 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EHMLMMCA_02422 2.66e-217 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
EHMLMMCA_02423 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EHMLMMCA_02424 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
EHMLMMCA_02425 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
EHMLMMCA_02426 0.0 ylqG - - - - - - -
EHMLMMCA_02427 2.89e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EHMLMMCA_02428 4.89e-201 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EHMLMMCA_02429 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EHMLMMCA_02430 2.41e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
EHMLMMCA_02431 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EHMLMMCA_02432 9.77e-80 ylqD - - S - - - YlqD protein
EHMLMMCA_02433 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
EHMLMMCA_02434 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
EHMLMMCA_02435 3.95e-308 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EHMLMMCA_02436 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EHMLMMCA_02437 1.38e-113 - - - - - - - -
EHMLMMCA_02438 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EHMLMMCA_02439 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
EHMLMMCA_02440 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EHMLMMCA_02441 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
EHMLMMCA_02442 3.5e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
EHMLMMCA_02443 1.31e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
EHMLMMCA_02444 8.33e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EHMLMMCA_02445 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
EHMLMMCA_02446 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EHMLMMCA_02447 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
EHMLMMCA_02448 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
EHMLMMCA_02449 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
EHMLMMCA_02450 3.65e-78 yloU - - S - - - protein conserved in bacteria
EHMLMMCA_02451 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
EHMLMMCA_02452 2.83e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
EHMLMMCA_02453 1.1e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
EHMLMMCA_02454 3.92e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EHMLMMCA_02455 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
EHMLMMCA_02456 3.54e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
EHMLMMCA_02457 5.3e-264 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EHMLMMCA_02458 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EHMLMMCA_02459 1.28e-225 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EHMLMMCA_02460 8.3e-110 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EHMLMMCA_02461 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EHMLMMCA_02462 5.98e-285 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EHMLMMCA_02463 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EHMLMMCA_02464 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
EHMLMMCA_02465 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
EHMLMMCA_02466 1.19e-201 yloC - - S - - - stress-induced protein
EHMLMMCA_02467 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
EHMLMMCA_02468 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
EHMLMMCA_02469 2.28e-108 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
EHMLMMCA_02470 1.69e-186 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
EHMLMMCA_02471 1.24e-186 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
EHMLMMCA_02472 5.56e-142 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
EHMLMMCA_02473 2.62e-285 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
EHMLMMCA_02474 1.04e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
EHMLMMCA_02475 1.03e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
EHMLMMCA_02477 1.22e-146 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EHMLMMCA_02478 1.09e-162 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EHMLMMCA_02479 1.05e-221 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EHMLMMCA_02480 1.57e-184 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
EHMLMMCA_02481 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
EHMLMMCA_02482 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
EHMLMMCA_02483 9.71e-317 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EHMLMMCA_02484 2.44e-212 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
EHMLMMCA_02485 6.15e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
EHMLMMCA_02486 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EHMLMMCA_02487 3.52e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
EHMLMMCA_02488 6.39e-102 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EHMLMMCA_02489 3.74e-82 ylyA - - T - - - COG1734 DnaK suppressor protein
EHMLMMCA_02490 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EHMLMMCA_02491 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
EHMLMMCA_02492 1.49e-178 ylmH - - S - - - conserved protein, contains S4-like domain
EHMLMMCA_02493 1.22e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
EHMLMMCA_02494 1.28e-86 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EHMLMMCA_02495 9.03e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EHMLMMCA_02496 3.73e-203 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
EHMLMMCA_02497 1.46e-50 ylmC - - S - - - sporulation protein
EHMLMMCA_02498 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
EHMLMMCA_02499 1.1e-188 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
EHMLMMCA_02500 7.99e-180 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHMLMMCA_02501 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHMLMMCA_02502 2.49e-219 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
EHMLMMCA_02503 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
EHMLMMCA_02504 2.14e-259 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EHMLMMCA_02505 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EHMLMMCA_02506 5.37e-76 sbp - - S - - - small basic protein
EHMLMMCA_02507 1.06e-132 ylxX - - S - - - protein conserved in bacteria
EHMLMMCA_02508 2.23e-142 ylxW - - S - - - protein conserved in bacteria
EHMLMMCA_02509 1.18e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EHMLMMCA_02510 1.3e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
EHMLMMCA_02511 2.59e-255 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EHMLMMCA_02512 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
EHMLMMCA_02513 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EHMLMMCA_02514 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EHMLMMCA_02515 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EHMLMMCA_02516 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
EHMLMMCA_02517 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
EHMLMMCA_02518 3.42e-68 ftsL - - D - - - Essential cell division protein
EHMLMMCA_02519 1.94e-217 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EHMLMMCA_02520 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
EHMLMMCA_02521 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EHMLMMCA_02522 1.86e-213 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EHMLMMCA_02523 1.33e-115 ylbP - - K - - - n-acetyltransferase
EHMLMMCA_02524 4.72e-107 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
EHMLMMCA_02525 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
EHMLMMCA_02526 6.94e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
EHMLMMCA_02528 1.56e-296 ylbM - - S - - - Belongs to the UPF0348 family
EHMLMMCA_02529 7.81e-239 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
EHMLMMCA_02530 5.17e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
EHMLMMCA_02531 5.5e-282 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
EHMLMMCA_02532 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EHMLMMCA_02533 6.07e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
EHMLMMCA_02534 5.1e-51 ylbG - - S - - - UPF0298 protein
EHMLMMCA_02535 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
EHMLMMCA_02536 1.73e-48 ylbE - - S - - - YlbE-like protein
EHMLMMCA_02537 3.24e-89 ylbD - - S - - - Putative coat protein
EHMLMMCA_02538 6.24e-256 ylbC - - S - - - protein with SCP PR1 domains
EHMLMMCA_02539 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
EHMLMMCA_02540 1.61e-81 ylbA - - S - - - YugN-like family
EHMLMMCA_02541 4.06e-212 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
EHMLMMCA_02542 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
EHMLMMCA_02543 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
EHMLMMCA_02544 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EHMLMMCA_02545 2.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
EHMLMMCA_02546 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
EHMLMMCA_02547 2e-212 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
EHMLMMCA_02548 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EHMLMMCA_02549 3.49e-271 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
EHMLMMCA_02550 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
EHMLMMCA_02551 4.25e-220 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
EHMLMMCA_02552 1.09e-110 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EHMLMMCA_02553 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
EHMLMMCA_02554 2.97e-127 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EHMLMMCA_02555 8.92e-44 ylaI - - S - - - protein conserved in bacteria
EHMLMMCA_02556 4.4e-63 ylaH - - S - - - YlaH-like protein
EHMLMMCA_02557 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
EHMLMMCA_02558 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
EHMLMMCA_02559 5.7e-56 ylaE - - - - - - -
EHMLMMCA_02561 3.56e-115 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EHMLMMCA_02562 1.44e-56 ylaB - - - - - - -
EHMLMMCA_02563 0.0 ylaA - - - - - - -
EHMLMMCA_02564 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
EHMLMMCA_02565 8.61e-222 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EHMLMMCA_02566 1.21e-99 ykzC - - S - - - Acetyltransferase (GNAT) family
EHMLMMCA_02567 1.91e-194 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
EHMLMMCA_02568 4.48e-35 ykzI - - - - - - -
EHMLMMCA_02569 5.28e-152 yktB - - S - - - Belongs to the UPF0637 family
EHMLMMCA_02570 2.22e-55 yktA - - S - - - Belongs to the UPF0223 family
EHMLMMCA_02571 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
EHMLMMCA_02572 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
EHMLMMCA_02573 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EHMLMMCA_02574 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EHMLMMCA_02575 3.52e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EHMLMMCA_02576 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EHMLMMCA_02577 2.22e-140 ykyA - - L - - - Putative cell-wall binding lipoprotein
EHMLMMCA_02578 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
EHMLMMCA_02579 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EHMLMMCA_02580 1.18e-186 ykrA - - S - - - hydrolases of the HAD superfamily
EHMLMMCA_02581 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
EHMLMMCA_02582 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EHMLMMCA_02583 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EHMLMMCA_02584 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
EHMLMMCA_02585 6.63e-196 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
EHMLMMCA_02586 4.59e-307 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
EHMLMMCA_02587 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
EHMLMMCA_02588 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
EHMLMMCA_02589 1.09e-18 - - - S - - - Uncharacterized protein YkpC
EHMLMMCA_02590 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
EHMLMMCA_02591 3.9e-213 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EHMLMMCA_02592 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EHMLMMCA_02593 5.43e-52 ykoA - - - - - - -
EHMLMMCA_02594 1.42e-133 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
EHMLMMCA_02595 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
EHMLMMCA_02596 4.75e-214 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
EHMLMMCA_02597 7.41e-176 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
EHMLMMCA_02598 3.33e-266 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
EHMLMMCA_02599 8.67e-160 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHMLMMCA_02600 3.32e-233 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHMLMMCA_02601 1.31e-150 yknW - - S - - - Yip1 domain
EHMLMMCA_02602 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
EHMLMMCA_02603 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
EHMLMMCA_02604 6.92e-45 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EHMLMMCA_02605 2.22e-108 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
EHMLMMCA_02606 7.8e-119 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
EHMLMMCA_02607 4.29e-313 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
EHMLMMCA_02608 1.47e-242 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EHMLMMCA_02609 9.21e-142 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
EHMLMMCA_02610 5.72e-199 yknT - - - ko:K06437 - ko00000 -
EHMLMMCA_02611 4.71e-122 rok - - K - - - Repressor of ComK
EHMLMMCA_02612 1.47e-104 ykuV - - CO - - - thiol-disulfide
EHMLMMCA_02613 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
EHMLMMCA_02614 8.27e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
EHMLMMCA_02615 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
EHMLMMCA_02616 1.33e-274 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EHMLMMCA_02617 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EHMLMMCA_02618 6.2e-103 fld - - C ko:K03839 - ko00000 Flavodoxin
EHMLMMCA_02619 7.7e-226 ykuO - - - - - - -
EHMLMMCA_02620 2.05e-109 - - - C ko:K03839 - ko00000 Flavodoxin domain
EHMLMMCA_02621 1.54e-214 ccpC - - K - - - Transcriptional regulator
EHMLMMCA_02622 5.15e-100 ykuL - - S - - - CBS domain
EHMLMMCA_02623 7.83e-38 ykzF - - S - - - Antirepressor AbbA
EHMLMMCA_02624 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
EHMLMMCA_02625 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
EHMLMMCA_02626 1.76e-298 ykuI - - T - - - Diguanylate phosphodiesterase
EHMLMMCA_02627 1.06e-181 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHMLMMCA_02628 2.45e-210 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
EHMLMMCA_02629 5.84e-115 ykuD - - S - - - protein conserved in bacteria
EHMLMMCA_02630 2.55e-305 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EHMLMMCA_02631 3.71e-110 ykyB - - S - - - YkyB-like protein
EHMLMMCA_02632 4.95e-216 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
EHMLMMCA_02633 1.05e-22 - - - - - - - -
EHMLMMCA_02634 4.01e-281 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EHMLMMCA_02635 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHMLMMCA_02636 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
EHMLMMCA_02637 5.36e-172 ykwD - - J - - - protein with SCP PR1 domains
EHMLMMCA_02638 1.4e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
EHMLMMCA_02639 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EHMLMMCA_02640 5.32e-163 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EHMLMMCA_02641 2.49e-256 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
EHMLMMCA_02642 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
EHMLMMCA_02643 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EHMLMMCA_02644 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
EHMLMMCA_02645 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHMLMMCA_02646 6.87e-168 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
EHMLMMCA_02648 6.34e-228 ykvZ - - K - - - Transcriptional regulator
EHMLMMCA_02649 1.11e-263 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
EHMLMMCA_02650 3.99e-09 - - - - - - - -
EHMLMMCA_02651 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
EHMLMMCA_02652 1.12e-114 stoA - - CO - - - thiol-disulfide
EHMLMMCA_02653 6.46e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EHMLMMCA_02654 9.09e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
EHMLMMCA_02655 2.6e-39 - - - - - - - -
EHMLMMCA_02656 5.43e-35 ykvS - - S - - - protein conserved in bacteria
EHMLMMCA_02657 2.2e-61 ykvR - - S - - - Protein of unknown function (DUF3219)
EHMLMMCA_02658 3.53e-204 - - - G - - - Glycosyl hydrolases family 18
EHMLMMCA_02659 2.87e-43 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
EHMLMMCA_02660 2.58e-273 - - - M - - - Glycosyl transferases group 1
EHMLMMCA_02661 2.11e-169 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
EHMLMMCA_02662 4.98e-78 - - - K - - - HxlR-like helix-turn-helix
EHMLMMCA_02663 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EHMLMMCA_02664 1.45e-178 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
EHMLMMCA_02665 4.03e-104 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
EHMLMMCA_02666 6.42e-161 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EHMLMMCA_02667 6.76e-227 ykvI - - S - - - membrane
EHMLMMCA_02668 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
EHMLMMCA_02669 1.65e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
EHMLMMCA_02670 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
EHMLMMCA_02671 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
EHMLMMCA_02672 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
EHMLMMCA_02673 5.62e-93 eag - - - - - - -
EHMLMMCA_02675 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
EHMLMMCA_02676 8.7e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EHMLMMCA_02677 1.84e-146 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
EHMLMMCA_02678 1.77e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EHMLMMCA_02679 2.29e-293 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
EHMLMMCA_02680 2.67e-293 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EHMLMMCA_02681 1.99e-193 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EHMLMMCA_02682 3.92e-290 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EHMLMMCA_02683 2.2e-251 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EHMLMMCA_02685 1.53e-112 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EHMLMMCA_02686 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHMLMMCA_02687 3.34e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
EHMLMMCA_02688 1.77e-28 ykzE - - - - - - -
EHMLMMCA_02690 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
EHMLMMCA_02691 1.61e-198 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
EHMLMMCA_02692 7.68e-160 ykrK - - S - - - Domain of unknown function (DUF1836)
EHMLMMCA_02693 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
EHMLMMCA_02694 1.27e-209 rsgI - - S - - - Anti-sigma factor N-terminus
EHMLMMCA_02695 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHMLMMCA_02696 6.3e-225 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
EHMLMMCA_02697 2.08e-144 ykoX - - S - - - membrane-associated protein
EHMLMMCA_02698 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
EHMLMMCA_02699 7.55e-206 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EHMLMMCA_02700 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
EHMLMMCA_02701 5.72e-239 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
EHMLMMCA_02702 0.0 ykoS - - - - - - -
EHMLMMCA_02703 4.35e-198 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
EHMLMMCA_02704 1.44e-128 ykoP - - G - - - polysaccharide deacetylase
EHMLMMCA_02705 3.88e-271 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
EHMLMMCA_02706 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
EHMLMMCA_02707 3.04e-36 ykoL - - - - - - -
EHMLMMCA_02708 1.63e-25 - - - - - - - -
EHMLMMCA_02709 1.49e-70 tnrA - - K - - - transcriptional
EHMLMMCA_02710 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
EHMLMMCA_02712 1.45e-08 - - - - - - - -
EHMLMMCA_02713 1.3e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
EHMLMMCA_02714 5.55e-145 ykoI - - S - - - Peptidase propeptide and YPEB domain
EHMLMMCA_02715 2.02e-305 ykoH - - T - - - Histidine kinase
EHMLMMCA_02716 1.28e-160 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHMLMMCA_02717 4.92e-142 ykoF - - S - - - YKOF-related Family
EHMLMMCA_02718 1.39e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
EHMLMMCA_02719 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EHMLMMCA_02720 3.12e-174 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
EHMLMMCA_02721 8.04e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EHMLMMCA_02722 1.49e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EHMLMMCA_02723 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EHMLMMCA_02724 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
EHMLMMCA_02725 3.32e-93 ohrB - - O - - - Organic hydroperoxide resistance protein
EHMLMMCA_02726 1.42e-97 ohrR - - K - - - COG1846 Transcriptional regulators
EHMLMMCA_02727 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
EHMLMMCA_02728 1.6e-289 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EHMLMMCA_02729 3.68e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EHMLMMCA_02730 4.77e-217 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
EHMLMMCA_02731 1.36e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
EHMLMMCA_02732 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
EHMLMMCA_02733 3.59e-128 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EHMLMMCA_02734 6.42e-128 ykkA - - S - - - Protein of unknown function (DUF664)
EHMLMMCA_02735 3.95e-167 ykjA - - S - - - Protein of unknown function (DUF421)
EHMLMMCA_02736 3.55e-14 - - - - - - - -
EHMLMMCA_02737 5.35e-289 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EHMLMMCA_02738 1.55e-119 ykhA - - I - - - Acyl-CoA hydrolase
EHMLMMCA_02739 1.78e-205 ykgA - - E - - - Amidinotransferase
EHMLMMCA_02740 8.08e-261 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
EHMLMMCA_02741 4.88e-236 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHMLMMCA_02742 1.53e-211 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
EHMLMMCA_02743 4.85e-257 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
EHMLMMCA_02744 2.64e-222 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
EHMLMMCA_02745 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
EHMLMMCA_02746 1.64e-237 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHMLMMCA_02747 3.02e-224 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHMLMMCA_02748 2.28e-202 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHMLMMCA_02749 9.45e-195 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
EHMLMMCA_02750 8.2e-179 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
EHMLMMCA_02751 6.72e-288 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EHMLMMCA_02753 6.35e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
EHMLMMCA_02754 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EHMLMMCA_02755 8.07e-233 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
EHMLMMCA_02756 8.98e-310 steT - - E ko:K03294 - ko00000 amino acid
EHMLMMCA_02757 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
EHMLMMCA_02758 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
EHMLMMCA_02759 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
EHMLMMCA_02760 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
EHMLMMCA_02762 1.85e-208 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
EHMLMMCA_02763 3.87e-51 xhlB - - S - - - SPP1 phage holin
EHMLMMCA_02764 7.71e-52 xhlA - - S - - - Haemolysin XhlA
EHMLMMCA_02765 2.81e-194 xepA - - - - - - -
EHMLMMCA_02766 4.47e-31 xkdX - - - - - - -
EHMLMMCA_02767 5.22e-59 xkdW - - S - - - XkdW protein
EHMLMMCA_02768 0.0 - - - - - - - -
EHMLMMCA_02769 8.94e-56 - - - - - - - -
EHMLMMCA_02770 6.51e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
EHMLMMCA_02771 7.59e-245 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
EHMLMMCA_02772 1.56e-89 xkdS - - S - - - Protein of unknown function (DUF2634)
EHMLMMCA_02773 4.32e-53 xkdR - - S - - - Protein of unknown function (DUF2577)
EHMLMMCA_02774 2.31e-232 xkdQ - - G - - - NLP P60 protein
EHMLMMCA_02775 1.7e-156 xkdP - - S - - - Lysin motif
EHMLMMCA_02776 0.0 xkdO - - L - - - Transglycosylase SLT domain
EHMLMMCA_02777 3.34e-101 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
EHMLMMCA_02778 6.01e-99 xkdM - - S - - - Phage tail tube protein
EHMLMMCA_02779 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
EHMLMMCA_02780 4.59e-98 xkdJ - - - - - - -
EHMLMMCA_02781 5.61e-113 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
EHMLMMCA_02782 1.75e-84 yqbH - - S - - - Domain of unknown function (DUF3599)
EHMLMMCA_02783 9.07e-80 yqbG - - S - - - Protein of unknown function (DUF3199)
EHMLMMCA_02784 3.91e-217 xkdG - - S - - - Phage capsid family
EHMLMMCA_02785 9.88e-177 xkdF3 - - L - - - Putative phage serine protease XkdF
EHMLMMCA_02786 0.0 yqbA - - S - - - portal protein
EHMLMMCA_02787 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
EHMLMMCA_02788 5.58e-178 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
EHMLMMCA_02789 2.72e-108 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
EHMLMMCA_02793 3.55e-151 xkdC - - L - - - Bacterial dnaA protein
EHMLMMCA_02794 1.78e-201 xkdB - - K - - - sequence-specific DNA binding
EHMLMMCA_02796 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
EHMLMMCA_02797 7.3e-143 xkdA - - E - - - IrrE N-terminal-like domain
EHMLMMCA_02798 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
EHMLMMCA_02799 5.99e-143 yjqB - - S - - - Pfam:DUF867
EHMLMMCA_02800 1.35e-80 yjqA - - S - - - Bacterial PH domain
EHMLMMCA_02801 1.12e-219 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
EHMLMMCA_02802 1.79e-55 - - - S - - - YCII-related domain
EHMLMMCA_02804 1.6e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
EHMLMMCA_02805 6.08e-314 VCP - - O - - - AAA domain (dynein-related subfamily)
EHMLMMCA_02806 2.82e-105 yjoA - - S - - - DinB family
EHMLMMCA_02807 1.59e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
EHMLMMCA_02808 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
EHMLMMCA_02809 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
EHMLMMCA_02810 8.11e-237 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
EHMLMMCA_02811 1.37e-289 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
EHMLMMCA_02812 5.47e-196 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
EHMLMMCA_02813 2.27e-272 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
EHMLMMCA_02814 1.21e-241 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
EHMLMMCA_02815 6.68e-238 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
EHMLMMCA_02816 6.16e-314 - - - G ko:K03292 - ko00000 symporter YjmB
EHMLMMCA_02817 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
EHMLMMCA_02818 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
EHMLMMCA_02819 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
EHMLMMCA_02820 2.46e-118 yjlB - - S - - - Cupin domain
EHMLMMCA_02821 1.81e-224 yjlA - - EG - - - Putative multidrug resistance efflux transporter
EHMLMMCA_02822 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
EHMLMMCA_02823 5.23e-155 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
EHMLMMCA_02824 2.79e-185 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
EHMLMMCA_02825 1.11e-41 - - - - - - - -
EHMLMMCA_02826 5.05e-279 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
EHMLMMCA_02827 2.74e-285 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EHMLMMCA_02829 1.57e-148 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
EHMLMMCA_02831 2.65e-121 yjgD - - S - - - Protein of unknown function (DUF1641)
EHMLMMCA_02832 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
EHMLMMCA_02833 1e-132 yjgB - - S - - - Domain of unknown function (DUF4309)
EHMLMMCA_02834 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
EHMLMMCA_02835 3.24e-219 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
EHMLMMCA_02836 1.13e-29 yjfB - - S - - - Putative motility protein
EHMLMMCA_02837 2.22e-108 - - - S - - - Protein of unknown function (DUF2690)
EHMLMMCA_02838 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
EHMLMMCA_02840 1.46e-221 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
EHMLMMCA_02841 2.31e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
EHMLMMCA_02842 5.97e-39 - - - S - - - Domain of unknown function (DUF4177)
EHMLMMCA_02843 2.89e-105 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EHMLMMCA_02845 2.54e-117 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
EHMLMMCA_02846 5.34e-75 yjdF3 - - S - - - Protein of unknown function (DUF2992)
EHMLMMCA_02847 1.03e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
EHMLMMCA_02848 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHMLMMCA_02849 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
EHMLMMCA_02850 0.000759 - - - - - - - -
EHMLMMCA_02851 1.33e-178 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
EHMLMMCA_02852 5.19e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
EHMLMMCA_02853 3.01e-161 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
EHMLMMCA_02857 9.15e-312 - - - M - - - nucleic acid phosphodiester bond hydrolysis
EHMLMMCA_02858 6.59e-41 - - - - - - - -
EHMLMMCA_02859 2.03e-43 - - - - - - - -
EHMLMMCA_02860 1.05e-55 - - - S - - - YolD-like protein
EHMLMMCA_02862 4.75e-38 - - - K - - - Helix-turn-helix domain
EHMLMMCA_02865 1.04e-50 - - - S - - - Bacterial toxin 44
EHMLMMCA_02867 9.41e-139 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
EHMLMMCA_02868 7.53e-40 xhlB - - S - - - SPP1 phage holin
EHMLMMCA_02869 3.83e-37 xhlA - - S - - - Haemolysin XhlA
EHMLMMCA_02874 3.33e-212 - - - L - - - Phage minor structural protein
EHMLMMCA_02875 9e-41 - - - S - - - Phage tail protein
EHMLMMCA_02876 7.39e-149 - - - D - - - minor tail protein
EHMLMMCA_02877 4.01e-47 - - - S - - - Bacteriophage Gp15 protein
EHMLMMCA_02879 1.95e-52 - - - N - - - Belongs to the glycosyl hydrolase family 6
EHMLMMCA_02881 7.09e-28 - - - S - - - Minor capsid protein
EHMLMMCA_02883 3.29e-27 - - - - - - - -
EHMLMMCA_02884 5.32e-10 chiA - - G - - - Belongs to the glycosyl hydrolase 18 family
EHMLMMCA_02885 1.91e-122 - - - - - - - -
EHMLMMCA_02886 9.1e-26 - - - - - - - -
EHMLMMCA_02887 2.15e-114 - - - S - - - Phage minor capsid protein 2
EHMLMMCA_02888 2.48e-212 - - - S - - - portal protein
EHMLMMCA_02889 3.71e-256 - - - S ko:K06909 - ko00000 Terminase RNAseH like domain
EHMLMMCA_02890 2.51e-114 yqaS - - L - - - DNA packaging
EHMLMMCA_02891 1.01e-65 - - - S - - - YjcQ protein
EHMLMMCA_02892 2.31e-99 yjcP - - - - - - -
EHMLMMCA_02893 7.39e-53 - - - L - - - Transposase
EHMLMMCA_02899 9.08e-78 - - - S - - - dUTPase
EHMLMMCA_02901 1.76e-11 - - - S - - - Bacillus cereus group antimicrobial protein
EHMLMMCA_02905 1.65e-30 yqaO - - S - - - Phage-like element PBSX protein XtrA
EHMLMMCA_02907 1.5e-69 - - - S - - - Protein of unknown function (DUF1064)
EHMLMMCA_02910 6.59e-118 yqaM - - L - - - IstB-like ATP binding protein
EHMLMMCA_02911 1.42e-97 yqaL - - L - - - DnaD domain protein
EHMLMMCA_02913 3.85e-89 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
EHMLMMCA_02914 2.4e-124 - - - - - - - -
EHMLMMCA_02920 5.38e-22 - - - - - - - -
EHMLMMCA_02922 6.28e-57 - - - S - - - DNA binding
EHMLMMCA_02923 8.03e-22 - - - S - - - Helix-turn-helix domain
EHMLMMCA_02924 3e-05 - - - K - - - Helix-turn-helix domain
EHMLMMCA_02925 3.26e-21 - - - K - - - Helix-turn-helix XRE-family like proteins
EHMLMMCA_02928 1.64e-61 xkdA - - E - - - IrrE N-terminal-like domain
EHMLMMCA_02929 3.02e-180 int7 - - L - - - Belongs to the 'phage' integrase family
EHMLMMCA_02931 1.74e-272 yjcL - - S - - - Protein of unknown function (DUF819)
EHMLMMCA_02932 9.74e-126 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
EHMLMMCA_02933 7.47e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
EHMLMMCA_02934 4.65e-272 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
EHMLMMCA_02935 1.63e-178 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
EHMLMMCA_02936 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
EHMLMMCA_02937 7.75e-94 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EHMLMMCA_02938 2.12e-49 - - - - - - - -
EHMLMMCA_02939 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
EHMLMMCA_02940 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
EHMLMMCA_02943 5.03e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
EHMLMMCA_02944 2.34e-66 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
EHMLMMCA_02945 9.3e-32 cotW - - - ko:K06341 - ko00000 -
EHMLMMCA_02946 1.23e-95 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
EHMLMMCA_02947 6.3e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
EHMLMMCA_02948 3.92e-107 cotZ - - S ko:K06344 - ko00000 Spore coat protein
EHMLMMCA_02949 5.16e-104 yjbX - - S - - - Spore coat protein
EHMLMMCA_02950 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
EHMLMMCA_02951 4.85e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
EHMLMMCA_02952 7.21e-237 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EHMLMMCA_02953 6.78e-174 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
EHMLMMCA_02954 2.18e-41 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
EHMLMMCA_02955 1.22e-272 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
EHMLMMCA_02956 2.71e-137 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
EHMLMMCA_02957 8.1e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EHMLMMCA_02958 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
EHMLMMCA_02959 1.15e-180 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
EHMLMMCA_02960 1.28e-203 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
EHMLMMCA_02961 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EHMLMMCA_02962 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
EHMLMMCA_02963 1.87e-81 yjbL - - S - - - Belongs to the UPF0738 family
EHMLMMCA_02964 2.98e-129 yjbK - - S - - - protein conserved in bacteria
EHMLMMCA_02965 9.78e-127 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EHMLMMCA_02966 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
EHMLMMCA_02967 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
EHMLMMCA_02968 2.68e-28 - - - - - - - -
EHMLMMCA_02969 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
EHMLMMCA_02970 2.53e-281 coiA - - S ko:K06198 - ko00000 Competence protein
EHMLMMCA_02971 4.65e-149 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
EHMLMMCA_02972 7.1e-144 yjbE - - P - - - Integral membrane protein TerC family
EHMLMMCA_02973 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EHMLMMCA_02974 8.88e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EHMLMMCA_02975 9.6e-260 yjbB - - EGP - - - Major Facilitator Superfamily
EHMLMMCA_02976 1.27e-219 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHMLMMCA_02977 1.12e-248 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHMLMMCA_02978 1.07e-211 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHMLMMCA_02979 1.03e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHMLMMCA_02980 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
EHMLMMCA_02981 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
EHMLMMCA_02982 3.18e-190 yjbA - - S - - - Belongs to the UPF0736 family
EHMLMMCA_02983 1.03e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHMLMMCA_02984 6.73e-216 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHMLMMCA_02985 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
EHMLMMCA_02986 4.01e-235 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHMLMMCA_02987 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHMLMMCA_02988 9.1e-191 yjaZ - - O - - - Zn-dependent protease
EHMLMMCA_02989 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EHMLMMCA_02990 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EHMLMMCA_02991 2.66e-35 yjzB - - - - - - -
EHMLMMCA_02992 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
EHMLMMCA_02993 3.7e-234 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
EHMLMMCA_02994 1.49e-131 yjaV - - - - - - -
EHMLMMCA_02995 4.88e-182 yjaU - - I - - - carboxylic ester hydrolase activity
EHMLMMCA_02996 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
EHMLMMCA_02997 2.51e-39 yjzC - - S - - - YjzC-like protein
EHMLMMCA_02998 4.27e-225 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EHMLMMCA_02999 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
EHMLMMCA_03000 9.47e-262 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
EHMLMMCA_03001 9.77e-278 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
EHMLMMCA_03002 5.4e-177 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
EHMLMMCA_03003 7.4e-295 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EHMLMMCA_03004 1.18e-251 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EHMLMMCA_03005 3.24e-114 yitZ - - G - - - Major Facilitator Superfamily
EHMLMMCA_03006 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
EHMLMMCA_03007 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
EHMLMMCA_03008 4.63e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
EHMLMMCA_03009 2.06e-184 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
EHMLMMCA_03010 3.19e-200 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
EHMLMMCA_03011 1.92e-08 - - - - - - - -
EHMLMMCA_03012 1.01e-25 - - - S - - - Protein of unknown function (DUF3813)
EHMLMMCA_03013 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
EHMLMMCA_03014 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EHMLMMCA_03015 7.5e-201 yitS - - S - - - protein conserved in bacteria
EHMLMMCA_03016 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
EHMLMMCA_03017 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
EHMLMMCA_03018 1.29e-121 - - - - - - - -
EHMLMMCA_03019 2.08e-77 - - - K - - - Transcriptional regulator PadR-like family
EHMLMMCA_03020 3.16e-125 - - - S - - - Sporulation delaying protein SdpA
EHMLMMCA_03021 4.76e-217 - - - - - - - -
EHMLMMCA_03022 4.16e-122 - - - - - - - -
EHMLMMCA_03023 9.21e-203 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
EHMLMMCA_03024 1.06e-77 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
EHMLMMCA_03025 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
EHMLMMCA_03026 5.09e-92 - - - S - - - Acetyltransferase (GNAT) domain
EHMLMMCA_03027 2.6e-196 yitH - - K - - - Acetyltransferase (GNAT) domain
EHMLMMCA_03028 4.1e-291 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EHMLMMCA_03029 2.14e-283 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
EHMLMMCA_03030 6.77e-145 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
EHMLMMCA_03031 4.31e-180 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
EHMLMMCA_03032 1.34e-162 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
EHMLMMCA_03033 1.3e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
EHMLMMCA_03034 1.6e-294 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
EHMLMMCA_03035 2.35e-144 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
EHMLMMCA_03036 2.25e-199 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EHMLMMCA_03037 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
EHMLMMCA_03038 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EHMLMMCA_03039 2.08e-128 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
EHMLMMCA_03040 9.94e-120 yisT - - S - - - DinB family
EHMLMMCA_03041 1e-246 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
EHMLMMCA_03042 1.83e-235 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
EHMLMMCA_03043 8.16e-207 yisR - - K - - - Transcriptional regulator
EHMLMMCA_03044 1.01e-310 yisQ - - V - - - Mate efflux family protein
EHMLMMCA_03045 1.54e-189 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
EHMLMMCA_03046 1.07e-114 yizA - - S - - - Damage-inducible protein DinB
EHMLMMCA_03047 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
EHMLMMCA_03048 7.42e-132 yisN - - S - - - Protein of unknown function (DUF2777)
EHMLMMCA_03049 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EHMLMMCA_03050 1.02e-74 yisL - - S - - - UPF0344 protein
EHMLMMCA_03051 7.64e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
EHMLMMCA_03052 1.48e-219 cotH - - M ko:K06330 - ko00000 Spore Coat
EHMLMMCA_03053 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
EHMLMMCA_03054 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
EHMLMMCA_03055 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
EHMLMMCA_03056 4.08e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
EHMLMMCA_03057 7.36e-34 gerPD - - S ko:K06302 - ko00000 Spore germination protein
EHMLMMCA_03058 4.08e-88 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
EHMLMMCA_03059 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
EHMLMMCA_03060 7.78e-66 yisB - - V - - - COG1403 Restriction endonuclease
EHMLMMCA_03061 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
EHMLMMCA_03062 1.2e-281 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EHMLMMCA_03063 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
EHMLMMCA_03064 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
EHMLMMCA_03065 9.3e-102 yhjR - - S - - - Rubrerythrin
EHMLMMCA_03066 2.05e-76 yhjQ - - C - - - COG1145 Ferredoxin
EHMLMMCA_03067 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
EHMLMMCA_03068 1.52e-264 - - - EGP - - - Transmembrane secretion effector
EHMLMMCA_03069 2.91e-258 yhjN - - S ko:K07120 - ko00000 membrane
EHMLMMCA_03070 8.8e-239 yhjM - - K - - - Transcriptional regulator
EHMLMMCA_03071 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
EHMLMMCA_03072 1.07e-204 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
EHMLMMCA_03073 3.27e-256 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
EHMLMMCA_03074 5.18e-272 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
EHMLMMCA_03075 3.85e-120 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
EHMLMMCA_03076 0.0 yhjG - - CH - - - FAD binding domain
EHMLMMCA_03077 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
EHMLMMCA_03078 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
EHMLMMCA_03079 4.13e-78 yhjD - - - - - - -
EHMLMMCA_03080 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
EHMLMMCA_03081 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHMLMMCA_03082 1.68e-55 yhjA - - S - - - Excalibur calcium-binding domain
EHMLMMCA_03083 4.74e-212 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
EHMLMMCA_03084 6.29e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
EHMLMMCA_03085 9.84e-45 yhzC - - S - - - IDEAL
EHMLMMCA_03086 7.82e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHMLMMCA_03087 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
EHMLMMCA_03088 1.85e-260 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
EHMLMMCA_03089 4.92e-117 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
EHMLMMCA_03090 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
EHMLMMCA_03091 2.46e-249 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
EHMLMMCA_03092 3.93e-140 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
EHMLMMCA_03093 2.77e-223 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
EHMLMMCA_03094 2.4e-232 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
EHMLMMCA_03095 2.54e-101 - - - K - - - acetyltransferase
EHMLMMCA_03096 6.91e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EHMLMMCA_03097 9.64e-308 yhfN - - O - - - Peptidase M48
EHMLMMCA_03098 2.78e-85 yhfM - - - - - - -
EHMLMMCA_03099 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
EHMLMMCA_03100 8.67e-143 yhfK - - GM - - - NmrA-like family
EHMLMMCA_03101 4.06e-245 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
EHMLMMCA_03102 5.93e-183 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
EHMLMMCA_03103 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EHMLMMCA_03104 1.07e-93 - - - S - - - ASCH
EHMLMMCA_03105 1.55e-252 yhfE - - G - - - peptidase M42
EHMLMMCA_03106 1.88e-177 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
EHMLMMCA_03107 8.77e-237 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EHMLMMCA_03108 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
EHMLMMCA_03109 1e-132 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
EHMLMMCA_03110 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EHMLMMCA_03111 2.4e-231 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
EHMLMMCA_03112 7.78e-261 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EHMLMMCA_03113 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
EHMLMMCA_03114 2.18e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
EHMLMMCA_03115 1.11e-43 - - - C - - - Rubrerythrin
EHMLMMCA_03116 1.15e-313 yhfA - - C - - - membrane
EHMLMMCA_03117 1.27e-290 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
EHMLMMCA_03118 1.01e-161 ecsC - - S - - - EcsC protein family
EHMLMMCA_03119 1.27e-271 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
EHMLMMCA_03120 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
EHMLMMCA_03121 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
EHMLMMCA_03122 7.5e-262 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EHMLMMCA_03123 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
EHMLMMCA_03124 1.74e-54 yhaH - - S - - - YtxH-like protein
EHMLMMCA_03125 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
EHMLMMCA_03126 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
EHMLMMCA_03127 5.71e-116 yhaK - - S - - - Putative zincin peptidase
EHMLMMCA_03128 2.29e-179 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
EHMLMMCA_03129 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
EHMLMMCA_03130 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
EHMLMMCA_03131 0.0 yhaN - - L - - - AAA domain
EHMLMMCA_03132 3.84e-300 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
EHMLMMCA_03133 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
EHMLMMCA_03134 2.76e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHMLMMCA_03135 2.29e-36 - - - S - - - YhzD-like protein
EHMLMMCA_03136 1.6e-172 yhaR - - I - - - enoyl-CoA hydratase
EHMLMMCA_03138 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
EHMLMMCA_03139 1.07e-266 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
EHMLMMCA_03140 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
EHMLMMCA_03141 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
EHMLMMCA_03142 1.58e-262 yhaZ - - L - - - DNA alkylation repair enzyme
EHMLMMCA_03143 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
EHMLMMCA_03144 4.85e-258 yheB - - S - - - Belongs to the UPF0754 family
EHMLMMCA_03145 1.6e-274 yheC - - HJ - - - YheC/D like ATP-grasp
EHMLMMCA_03146 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
EHMLMMCA_03147 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
EHMLMMCA_03148 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
EHMLMMCA_03149 3.31e-143 yheG - - GM - - - NAD(P)H-binding
EHMLMMCA_03150 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
EHMLMMCA_03151 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
EHMLMMCA_03152 5.24e-107 nhaX - - T - - - Belongs to the universal stress protein A family
EHMLMMCA_03153 6.66e-299 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
EHMLMMCA_03154 3.69e-196 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
EHMLMMCA_03155 1.83e-196 nodB1 - - G - - - deacetylase
EHMLMMCA_03156 4.66e-177 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
EHMLMMCA_03157 9.73e-239 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
EHMLMMCA_03158 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
EHMLMMCA_03159 1.56e-173 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
EHMLMMCA_03160 3.38e-86 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EHMLMMCA_03161 2.48e-66 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EHMLMMCA_03162 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
EHMLMMCA_03163 1.03e-283 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
EHMLMMCA_03164 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
EHMLMMCA_03165 2.54e-303 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
EHMLMMCA_03166 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
EHMLMMCA_03167 6.74e-244 yhdN - - C - - - Aldo keto reductase
EHMLMMCA_03168 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EHMLMMCA_03169 6.13e-258 yhdL - - S - - - Sigma factor regulator N-terminal
EHMLMMCA_03170 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
EHMLMMCA_03171 7.13e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EHMLMMCA_03172 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EHMLMMCA_03173 1.01e-308 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
EHMLMMCA_03174 8.94e-317 yhdG - - E ko:K03294 - ko00000 amino acid
EHMLMMCA_03175 1.58e-205 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHMLMMCA_03176 1.45e-258 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
EHMLMMCA_03177 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
EHMLMMCA_03178 5.92e-203 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
EHMLMMCA_03179 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
EHMLMMCA_03180 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
EHMLMMCA_03181 1.51e-306 ygxB - - M - - - Conserved TM helix
EHMLMMCA_03182 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
EHMLMMCA_03183 1.97e-274 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
EHMLMMCA_03184 1.02e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
EHMLMMCA_03185 1.65e-51 yhdB - - S - - - YhdB-like protein
EHMLMMCA_03186 5.68e-117 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
EHMLMMCA_03187 7.42e-142 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EHMLMMCA_03188 3.63e-270 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
EHMLMMCA_03189 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
EHMLMMCA_03190 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EHMLMMCA_03191 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EHMLMMCA_03192 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
EHMLMMCA_03193 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EHMLMMCA_03194 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EHMLMMCA_03195 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EHMLMMCA_03196 4.32e-155 yhcW - - S ko:K07025 - ko00000 hydrolase
EHMLMMCA_03197 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
EHMLMMCA_03198 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
EHMLMMCA_03199 4.78e-218 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
EHMLMMCA_03200 7.24e-134 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
EHMLMMCA_03201 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
EHMLMMCA_03202 1.68e-146 yhcQ - - M - - - Spore coat protein
EHMLMMCA_03203 3.64e-223 yhcP - - - - - - -
EHMLMMCA_03204 4.08e-106 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EHMLMMCA_03205 1.13e-70 yhcM - - - - - - -
EHMLMMCA_03206 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EHMLMMCA_03207 7.08e-251 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
EHMLMMCA_03208 1.34e-195 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
EHMLMMCA_03209 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
EHMLMMCA_03210 1.4e-211 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EHMLMMCA_03211 3.74e-212 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHMLMMCA_03212 3.38e-158 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHMLMMCA_03213 1.67e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
EHMLMMCA_03214 2.92e-69 - - - - - - - -
EHMLMMCA_03215 3.95e-59 yhcC - - - - - - -
EHMLMMCA_03216 4.87e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
EHMLMMCA_03217 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
EHMLMMCA_03218 3.8e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
EHMLMMCA_03219 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
EHMLMMCA_03220 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
EHMLMMCA_03221 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
EHMLMMCA_03222 4.08e-110 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
EHMLMMCA_03223 1.32e-95 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
EHMLMMCA_03224 2.29e-141 yhbD - - K - - - Protein of unknown function (DUF4004)
EHMLMMCA_03225 6.53e-113 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EHMLMMCA_03226 2.28e-224 yhbB - - S - - - Putative amidase domain
EHMLMMCA_03227 8.1e-282 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EHMLMMCA_03228 5.51e-147 yhzB - - S - - - B3/4 domain
EHMLMMCA_03230 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
EHMLMMCA_03231 2.79e-102 ygaO - - - - - - -
EHMLMMCA_03232 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EHMLMMCA_03234 9.35e-276 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
EHMLMMCA_03235 5.86e-190 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
EHMLMMCA_03236 7.24e-219 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
EHMLMMCA_03237 7.1e-176 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
EHMLMMCA_03238 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
EHMLMMCA_03240 0.0 ygaK - - C - - - Berberine and berberine like
EHMLMMCA_03241 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EHMLMMCA_03242 4.02e-172 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
EHMLMMCA_03243 3.88e-37 - - - - - - - -
EHMLMMCA_03244 2.22e-185 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
EHMLMMCA_03261 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EHMLMMCA_03262 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
EHMLMMCA_03263 5.46e-74 ygzB - - S - - - UPF0295 protein
EHMLMMCA_03264 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
EHMLMMCA_03265 2.92e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
EHMLMMCA_03266 5.64e-313 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
EHMLMMCA_03267 1.87e-238 ygaE - - S - - - Membrane
EHMLMMCA_03268 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
EHMLMMCA_03269 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
EHMLMMCA_03270 2.01e-49 ygaB - - S - - - YgaB-like protein
EHMLMMCA_03271 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
EHMLMMCA_03272 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHMLMMCA_03273 1.73e-48 yfhS - - - - - - -
EHMLMMCA_03274 5.31e-265 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
EHMLMMCA_03275 2.07e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
EHMLMMCA_03276 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
EHMLMMCA_03277 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
EHMLMMCA_03278 1.13e-217 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
EHMLMMCA_03279 1.66e-62 yfhL - - S - - - SdpI/YhfL protein family
EHMLMMCA_03280 4.18e-118 yfhK - - T - - - Bacterial SH3 domain homologues
EHMLMMCA_03281 8.95e-60 yfhJ - - S - - - WVELL protein
EHMLMMCA_03282 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
EHMLMMCA_03283 1.65e-266 yfhI - - EGP - - - -transporter
EHMLMMCA_03285 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
EHMLMMCA_03286 3.25e-181 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
EHMLMMCA_03287 2.19e-219 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
EHMLMMCA_03289 8.86e-35 yfhD - - S - - - YfhD-like protein
EHMLMMCA_03290 2.87e-138 yfhC - - C - - - nitroreductase
EHMLMMCA_03291 7.61e-215 yfhB - - S - - - PhzF family
EHMLMMCA_03292 7.36e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHMLMMCA_03293 1.54e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHMLMMCA_03294 3.15e-230 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
EHMLMMCA_03295 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EHMLMMCA_03296 2.11e-103 yfiV - - K - - - transcriptional
EHMLMMCA_03297 0.0 yfiU - - EGP - - - the major facilitator superfamily
EHMLMMCA_03298 1.15e-127 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
EHMLMMCA_03299 3.8e-252 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EHMLMMCA_03300 7.87e-128 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
EHMLMMCA_03301 1.89e-128 padR - - K - - - transcriptional
EHMLMMCA_03302 3.44e-262 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
EHMLMMCA_03303 8.44e-264 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
EHMLMMCA_03304 6.95e-211 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EHMLMMCA_03305 3.51e-145 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
EHMLMMCA_03306 2.94e-273 baeS - - T - - - Histidine kinase
EHMLMMCA_03308 4.21e-208 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
EHMLMMCA_03309 3.34e-83 yfiD3 - - S - - - DoxX
EHMLMMCA_03310 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
EHMLMMCA_03311 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
EHMLMMCA_03312 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHMLMMCA_03313 3.03e-181 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
EHMLMMCA_03314 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
EHMLMMCA_03315 1.6e-60 yfjA - - S - - - Belongs to the WXG100 family
EHMLMMCA_03316 1.59e-269 yfjB - - - - - - -
EHMLMMCA_03317 2.5e-185 yfjC - - - - - - -
EHMLMMCA_03318 3.52e-130 yfjD - - S - - - Family of unknown function (DUF5381)
EHMLMMCA_03319 1.3e-101 - - - S - - - Family of unknown function (DUF5381)
EHMLMMCA_03320 7.42e-75 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
EHMLMMCA_03321 8.16e-36 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
EHMLMMCA_03322 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
EHMLMMCA_03323 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EHMLMMCA_03324 1.34e-261 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EHMLMMCA_03325 8.81e-241 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EHMLMMCA_03326 1.36e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EHMLMMCA_03328 4.92e-104 yfjM - - S - - - Psort location Cytoplasmic, score
EHMLMMCA_03329 4.72e-241 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EHMLMMCA_03330 3.04e-59 - - - S - - - YfzA-like protein
EHMLMMCA_03331 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EHMLMMCA_03332 1.94e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EHMLMMCA_03333 7.8e-237 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
EHMLMMCA_03334 2.67e-191 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
EHMLMMCA_03335 7.24e-198 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
EHMLMMCA_03336 3.26e-36 yfjT - - - - - - -
EHMLMMCA_03337 1.76e-283 yfkA - - S - - - YfkB-like domain
EHMLMMCA_03338 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
EHMLMMCA_03339 5.24e-189 yfkD - - S - - - YfkD-like protein
EHMLMMCA_03340 1.34e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
EHMLMMCA_03341 1.9e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EHMLMMCA_03342 2.74e-11 - - - - - - - -
EHMLMMCA_03343 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
EHMLMMCA_03344 1.03e-66 yfkI - - S - - - gas vesicle protein
EHMLMMCA_03345 3.99e-106 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EHMLMMCA_03346 7.27e-42 yfkK - - S - - - Belongs to the UPF0435 family
EHMLMMCA_03347 2.07e-264 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EHMLMMCA_03348 7.78e-114 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
EHMLMMCA_03349 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
EHMLMMCA_03350 1.77e-159 frp - - C - - - nitroreductase
EHMLMMCA_03351 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
EHMLMMCA_03352 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
EHMLMMCA_03353 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHMLMMCA_03354 0.0 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
EHMLMMCA_03355 2.28e-271 yfkR - - S ko:K06297,ko:K06308 - ko00000 spore germination
EHMLMMCA_03357 2.56e-248 yfkT - - E ko:K06309 - ko00000 Spore germination protein
EHMLMMCA_03358 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
EHMLMMCA_03359 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
EHMLMMCA_03360 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
EHMLMMCA_03361 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
EHMLMMCA_03362 3.28e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
EHMLMMCA_03363 2.1e-65 yflH - - S - - - Protein of unknown function (DUF3243)
EHMLMMCA_03364 2.82e-26 yflI - - - - - - -
EHMLMMCA_03365 3.16e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
EHMLMMCA_03366 1.7e-157 yflK - - S - - - protein conserved in bacteria
EHMLMMCA_03367 4.22e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
EHMLMMCA_03368 1.67e-276 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EHMLMMCA_03369 1.98e-191 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
EHMLMMCA_03370 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
EHMLMMCA_03371 3.98e-230 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
EHMLMMCA_03372 1.88e-152 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
EHMLMMCA_03373 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
EHMLMMCA_03374 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
EHMLMMCA_03375 2.45e-307 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
EHMLMMCA_03376 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
EHMLMMCA_03377 3.01e-31 - - - S - - - Protein of unknown function (DUF3212)
EHMLMMCA_03378 2.88e-221 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
EHMLMMCA_03379 4.72e-220 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHMLMMCA_03380 2.1e-223 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHMLMMCA_03381 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
EHMLMMCA_03382 0.0 pkn1 - - S - - - Sulfatase-modifying factor enzyme 1
EHMLMMCA_03383 3.46e-268 - - - G - - - Major Facilitator Superfamily
EHMLMMCA_03384 1.71e-241 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
EHMLMMCA_03385 2.55e-105 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
EHMLMMCA_03386 8.46e-263 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
EHMLMMCA_03387 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EHMLMMCA_03388 1.46e-264 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
EHMLMMCA_03389 3.54e-90 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
EHMLMMCA_03390 6.48e-99 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
EHMLMMCA_03391 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EHMLMMCA_03392 2.97e-160 yfmS - - NT - - - chemotaxis protein
EHMLMMCA_03393 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EHMLMMCA_03394 1.39e-311 yfnA - - E ko:K03294 - ko00000 amino acid
EHMLMMCA_03395 1.34e-83 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
EHMLMMCA_03396 3.16e-50 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
EHMLMMCA_03397 6.21e-268 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EHMLMMCA_03398 2.34e-243 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
EHMLMMCA_03399 4.04e-285 yfnE - - S - - - Glycosyltransferase like family 2
EHMLMMCA_03400 6.61e-230 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
EHMLMMCA_03401 2.77e-219 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
EHMLMMCA_03402 1.46e-188 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
EHMLMMCA_03403 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
EHMLMMCA_03404 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
EHMLMMCA_03405 6.1e-255 yetN - - S - - - Protein of unknown function (DUF3900)
EHMLMMCA_03406 2.66e-137 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2326)
EHMLMMCA_03408 2.11e-94 - - - - - - - -
EHMLMMCA_03409 2.57e-38 yetM - - CH - - - FAD binding domain
EHMLMMCA_03410 2.55e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
EHMLMMCA_03411 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
EHMLMMCA_03412 3.59e-184 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EHMLMMCA_03413 9.79e-45 - - - - - - - -
EHMLMMCA_03414 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EHMLMMCA_03415 1.57e-71 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
EHMLMMCA_03416 3.66e-157 yetF - - S - - - membrane
EHMLMMCA_03417 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
EHMLMMCA_03418 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EHMLMMCA_03419 1.18e-226 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
EHMLMMCA_03420 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
EHMLMMCA_03421 0.0 yetA - - - - - - -
EHMLMMCA_03422 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
EHMLMMCA_03423 7.51e-159 - - - E - - - GDSL-like Lipase/Acylhydrolase
EHMLMMCA_03424 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
EHMLMMCA_03425 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
EHMLMMCA_03426 1.91e-143 - - - S - - - Protein of unknown function, DUF624
EHMLMMCA_03427 5.29e-165 yesU - - S - - - Domain of unknown function (DUF1961)
EHMLMMCA_03428 2.22e-165 - - - E - - - GDSL-like Lipase/Acylhydrolase
EHMLMMCA_03429 0.0 yesS - - K - - - Transcriptional regulator
EHMLMMCA_03430 5.63e-254 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
EHMLMMCA_03431 3.45e-208 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EHMLMMCA_03432 2.02e-218 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EHMLMMCA_03433 2.53e-315 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
EHMLMMCA_03434 1.98e-257 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
EHMLMMCA_03435 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHMLMMCA_03436 1.95e-132 yesL - - S - - - Protein of unknown function, DUF624
EHMLMMCA_03438 2.4e-130 yesJ - - K - - - Acetyltransferase (GNAT) family
EHMLMMCA_03439 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
EHMLMMCA_03440 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
EHMLMMCA_03441 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
EHMLMMCA_03442 1.23e-195 yesF - - GM - - - NAD(P)H-binding
EHMLMMCA_03443 4.95e-107 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
EHMLMMCA_03444 1.86e-134 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
EHMLMMCA_03446 6.29e-162 yeeN - - K - - - transcriptional regulatory protein
EHMLMMCA_03448 1.22e-271 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
EHMLMMCA_03450 2.85e-224 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
EHMLMMCA_03451 2.91e-228 - - - S - - - Bacterial EndoU nuclease
EHMLMMCA_03452 8.47e-55 - - - S - - - Immunity protein 22
EHMLMMCA_03453 0.000203 - - - - - - - -
EHMLMMCA_03454 2.59e-123 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
EHMLMMCA_03456 0.0 - - - K - - - SIR2-like domain
EHMLMMCA_03457 1.14e-27 - - - - - - - -
EHMLMMCA_03458 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EHMLMMCA_03459 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EHMLMMCA_03460 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHMLMMCA_03461 4.21e-190 yerO - - K - - - Transcriptional regulator
EHMLMMCA_03462 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EHMLMMCA_03463 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EHMLMMCA_03464 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EHMLMMCA_03465 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHMLMMCA_03466 1.32e-159 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
EHMLMMCA_03467 8.56e-251 yerI - - S - - - homoserine kinase type II (protein kinase fold)
EHMLMMCA_03469 1.77e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
EHMLMMCA_03470 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EHMLMMCA_03471 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
EHMLMMCA_03472 4.48e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EHMLMMCA_03473 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
EHMLMMCA_03474 6.27e-67 yerC - - S - - - protein conserved in bacteria
EHMLMMCA_03475 9.58e-244 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
EHMLMMCA_03476 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
EHMLMMCA_03477 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
EHMLMMCA_03478 2.04e-292 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
EHMLMMCA_03479 1.06e-95 - - - K - - - helix_turn_helix ASNC type
EHMLMMCA_03480 5.69e-298 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
EHMLMMCA_03481 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
EHMLMMCA_03482 3.62e-137 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EHMLMMCA_03483 1.71e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
EHMLMMCA_03484 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EHMLMMCA_03485 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EHMLMMCA_03486 2.71e-166 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EHMLMMCA_03487 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EHMLMMCA_03488 4.81e-167 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
EHMLMMCA_03489 6.85e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EHMLMMCA_03490 2.21e-276 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EHMLMMCA_03491 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EHMLMMCA_03492 6.33e-38 yebG - - S - - - NETI protein
EHMLMMCA_03493 2.66e-120 yebE - - S - - - UPF0316 protein
EHMLMMCA_03495 5.85e-165 yebC - - M - - - Membrane
EHMLMMCA_03496 3.27e-281 pbuG - - S ko:K06901 - ko00000,ko02000 permease
EHMLMMCA_03497 9.01e-312 - - - S - - - Domain of unknown function (DUF4179)
EHMLMMCA_03498 3.39e-115 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EHMLMMCA_03499 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
EHMLMMCA_03500 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
EHMLMMCA_03501 5.08e-282 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
EHMLMMCA_03502 2.79e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
EHMLMMCA_03503 1.76e-198 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EHMLMMCA_03504 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
EHMLMMCA_03505 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
EHMLMMCA_03506 7.65e-226 yeaA - - S - - - Protein of unknown function (DUF4003)
EHMLMMCA_03507 1.2e-200 - - - I - - - Alpha/beta hydrolase family
EHMLMMCA_03508 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
EHMLMMCA_03510 3.28e-207 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
EHMLMMCA_03511 1.79e-84 ydjM - - M - - - Lytic transglycolase
EHMLMMCA_03512 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
EHMLMMCA_03513 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EHMLMMCA_03514 1.87e-246 - - - S - - - Ion transport 2 domain protein
EHMLMMCA_03515 3.61e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
EHMLMMCA_03516 5.4e-175 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
EHMLMMCA_03517 1.04e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EHMLMMCA_03518 9.24e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
EHMLMMCA_03519 4.07e-219 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
EHMLMMCA_03520 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
EHMLMMCA_03521 3.55e-257 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
EHMLMMCA_03522 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
EHMLMMCA_03523 1.7e-196 ydjC - - S - - - Abhydrolase domain containing 18
EHMLMMCA_03524 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EHMLMMCA_03525 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EHMLMMCA_03526 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
EHMLMMCA_03527 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
EHMLMMCA_03528 3.55e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EHMLMMCA_03529 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
EHMLMMCA_03530 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EHMLMMCA_03531 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
EHMLMMCA_03532 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
EHMLMMCA_03533 1.34e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EHMLMMCA_03534 2.84e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
EHMLMMCA_03535 1.76e-163 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
EHMLMMCA_03536 9.02e-113 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
EHMLMMCA_03537 3.06e-237 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EHMLMMCA_03540 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EHMLMMCA_03543 6.94e-202 ydhU - - P ko:K07217 - ko00000 Catalase
EHMLMMCA_03544 2.02e-272 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
EHMLMMCA_03545 2.95e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
EHMLMMCA_03546 3.34e-212 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
EHMLMMCA_03547 7.75e-171 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
EHMLMMCA_03548 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EHMLMMCA_03549 3.23e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EHMLMMCA_03550 2.04e-68 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHMLMMCA_03551 7.97e-65 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHMLMMCA_03552 6.3e-255 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
EHMLMMCA_03553 3.29e-127 ydhK - - M - - - Protein of unknown function (DUF1541)
EHMLMMCA_03554 6.35e-230 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
EHMLMMCA_03555 2.78e-110 - - - K - - - Acetyltransferase (GNAT) domain
EHMLMMCA_03557 9.93e-91 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
EHMLMMCA_03558 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
EHMLMMCA_03559 5e-162 - - - - - - - -
EHMLMMCA_03560 7.9e-289 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
EHMLMMCA_03561 4.24e-308 ydhD - - M - - - Glycosyl hydrolase
EHMLMMCA_03562 5.24e-158 ydhC - - K - - - FCD
EHMLMMCA_03563 2.51e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
EHMLMMCA_03564 1.41e-264 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
EHMLMMCA_03565 3.29e-90 - - - K - - - Winged helix DNA-binding domain
EHMLMMCA_03566 6.42e-147 ydgI - - C - - - nitroreductase
EHMLMMCA_03567 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
EHMLMMCA_03568 2.06e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
EHMLMMCA_03569 3.3e-115 - - - S - - - DinB family
EHMLMMCA_03570 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
EHMLMMCA_03571 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
EHMLMMCA_03572 1.39e-111 yycN - - K - - - Acetyltransferase
EHMLMMCA_03573 8.18e-70 - - - S - - - DoxX-like family
EHMLMMCA_03574 3.19e-125 ydgC - - K - - - Bacterial regulatory proteins, tetR family
EHMLMMCA_03575 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
EHMLMMCA_03576 2.74e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
EHMLMMCA_03577 3.13e-99 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
EHMLMMCA_03578 4.44e-160 ydfS - - S - - - Protein of unknown function (DUF421)
EHMLMMCA_03579 6.08e-153 ydfR - - S - - - Protein of unknown function (DUF421)
EHMLMMCA_03581 5.33e-39 - - - - - - - -
EHMLMMCA_03582 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
EHMLMMCA_03584 8.92e-73 ydfQ - - CO - - - Thioredoxin
EHMLMMCA_03585 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
EHMLMMCA_03586 4.51e-237 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
EHMLMMCA_03587 8.12e-144 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
EHMLMMCA_03588 5e-197 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EHMLMMCA_03589 1.23e-188 - - - K - - - Bacterial transcription activator, effector binding domain
EHMLMMCA_03590 7.6e-149 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
EHMLMMCA_03591 7.67e-223 - - - S - - - Alpha/beta hydrolase family
EHMLMMCA_03592 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
EHMLMMCA_03593 2.3e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EHMLMMCA_03594 7.24e-247 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHMLMMCA_03596 1.87e-102 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EHMLMMCA_03597 1.5e-158 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
EHMLMMCA_03598 2.34e-148 ydfE - - S - - - Flavin reductase like domain
EHMLMMCA_03599 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EHMLMMCA_03600 1.97e-203 - - - EG - - - EamA-like transporter family
EHMLMMCA_03601 1.9e-189 - - - J - - - GNAT acetyltransferase
EHMLMMCA_03602 1.75e-294 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EHMLMMCA_03603 1.05e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
EHMLMMCA_03604 1.78e-134 ydeS - - K - - - Transcriptional regulator
EHMLMMCA_03605 2.78e-257 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
EHMLMMCA_03606 6.98e-142 ywrO - - S ko:K11748 - ko00000,ko02000 NADPH-quinone reductase (modulator of drug activity B)
EHMLMMCA_03607 5.03e-91 ydeP - - K - - - Transcriptional regulator
EHMLMMCA_03608 6.56e-194 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EHMLMMCA_03609 2.13e-74 - - - K - - - HxlR-like helix-turn-helix
EHMLMMCA_03610 1.9e-132 - - - S ko:K07002 - ko00000 Serine hydrolase
EHMLMMCA_03611 1.23e-95 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
EHMLMMCA_03612 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EHMLMMCA_03613 7.72e-196 ydeK - - EG - - - -transporter
EHMLMMCA_03614 4.22e-111 - - - K - - - Transcriptional regulator C-terminal region
EHMLMMCA_03615 3.3e-19 ptsH - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
EHMLMMCA_03616 2.4e-41 - - - S - - - SNARE associated Golgi protein
EHMLMMCA_03617 1.42e-139 - - - - - - - -
EHMLMMCA_03618 4.05e-135 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
EHMLMMCA_03619 9.2e-70 ydeH - - - - - - -
EHMLMMCA_03620 1.54e-276 ydeG - - EGP - - - Major facilitator superfamily
EHMLMMCA_03621 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EHMLMMCA_03622 2.45e-210 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
EHMLMMCA_03623 1.37e-221 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EHMLMMCA_03624 6.25e-213 - - - K - - - AraC-like ligand binding domain
EHMLMMCA_03625 1.14e-180 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EHMLMMCA_03626 3.57e-103 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
EHMLMMCA_03627 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
EHMLMMCA_03628 1.36e-244 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
EHMLMMCA_03629 1.21e-52 - - - - - - - -
EHMLMMCA_03630 1.8e-45 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
EHMLMMCA_03631 3.28e-11 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
EHMLMMCA_03632 2.57e-62 ydeH - - - - - - -
EHMLMMCA_03633 1.93e-259 abcA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
EHMLMMCA_03634 9.8e-262 - - - KLT - - - Protein kinase domain
EHMLMMCA_03639 3.08e-188 - - - KLT - - - Protein kinase domain
EHMLMMCA_03650 2.17e-107 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
EHMLMMCA_03651 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
EHMLMMCA_03652 1.86e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
EHMLMMCA_03653 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHMLMMCA_03654 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
EHMLMMCA_03655 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
EHMLMMCA_03656 1.31e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
EHMLMMCA_03657 8.56e-90 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
EHMLMMCA_03658 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
EHMLMMCA_03659 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
EHMLMMCA_03660 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
EHMLMMCA_03661 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
EHMLMMCA_03662 1.77e-282 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHMLMMCA_03663 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
EHMLMMCA_03664 1.32e-76 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EHMLMMCA_03665 3.32e-135 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
EHMLMMCA_03666 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
EHMLMMCA_03667 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
EHMLMMCA_03668 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EHMLMMCA_03669 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EHMLMMCA_03670 3.58e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
EHMLMMCA_03671 4.19e-75 ydbP - - CO - - - Thioredoxin
EHMLMMCA_03672 2.72e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EHMLMMCA_03674 1.49e-26 - - - S - - - Fur-regulated basic protein B
EHMLMMCA_03675 1.5e-279 ydbM - - I - - - acyl-CoA dehydrogenase
EHMLMMCA_03676 9.32e-70 ydbL - - - - - - -
EHMLMMCA_03677 2.99e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EHMLMMCA_03678 2.66e-218 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHMLMMCA_03679 1.32e-230 ydbI - - S - - - AI-2E family transporter
EHMLMMCA_03680 8.93e-290 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EHMLMMCA_03681 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
EHMLMMCA_03682 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
EHMLMMCA_03683 3.66e-253 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
EHMLMMCA_03684 6.41e-197 ydbD - - P ko:K07217 - ko00000 Catalase
EHMLMMCA_03685 1.49e-81 ydbC - - S - - - Domain of unknown function (DUF4937
EHMLMMCA_03686 7.58e-79 ydbB - - G - - - Cupin domain
EHMLMMCA_03687 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
EHMLMMCA_03688 5.86e-188 ydbA - - P - - - EcsC protein family
EHMLMMCA_03689 2.25e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
EHMLMMCA_03690 1.67e-42 ydaS - - S - - - membrane
EHMLMMCA_03691 2.25e-285 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
EHMLMMCA_03692 6.14e-53 - - - - - - - -
EHMLMMCA_03693 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
EHMLMMCA_03694 4.21e-100 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
EHMLMMCA_03695 0.0 ydaO - - E - - - amino acid
EHMLMMCA_03696 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
EHMLMMCA_03697 3.2e-303 ydaM - - M - - - Glycosyl transferase family group 2
EHMLMMCA_03698 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
EHMLMMCA_03699 1.33e-194 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
EHMLMMCA_03700 2.08e-265 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
EHMLMMCA_03701 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EHMLMMCA_03702 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
EHMLMMCA_03703 5.19e-60 ydzA - - EGP - - - Domain of unknown function (DUF3817)
EHMLMMCA_03704 2.65e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
EHMLMMCA_03705 5.24e-101 ydaG - - S - - - general stress protein
EHMLMMCA_03706 6.6e-134 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EHMLMMCA_03707 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
EHMLMMCA_03708 3.74e-207 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHMLMMCA_03709 1e-127 ydaC - - Q - - - Methyltransferase domain
EHMLMMCA_03710 0.0 ydaB - - IQ - - - acyl-CoA ligase
EHMLMMCA_03711 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
EHMLMMCA_03712 7.36e-221 ycsN - - S - - - Oxidoreductase
EHMLMMCA_03713 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
EHMLMMCA_03714 5.54e-62 yczJ - - S - - - biosynthesis
EHMLMMCA_03716 8.44e-154 ycsK - - E - - - anatomical structure formation involved in morphogenesis
EHMLMMCA_03717 3.8e-171 kipR - - K - - - Transcriptional regulator
EHMLMMCA_03718 1.99e-238 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
EHMLMMCA_03719 5.04e-173 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
EHMLMMCA_03720 2.01e-189 ycsI - - S - - - Belongs to the D-glutamate cyclase family
EHMLMMCA_03721 1.32e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
EHMLMMCA_03722 9.39e-182 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
EHMLMMCA_03723 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
EHMLMMCA_03725 2.29e-88 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
EHMLMMCA_03726 1.21e-143 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
EHMLMMCA_03727 1.32e-126 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
EHMLMMCA_03728 1.01e-256 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
EHMLMMCA_03729 5.13e-267 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
EHMLMMCA_03730 2.38e-94 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
EHMLMMCA_03731 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
EHMLMMCA_03732 9.44e-75 - - - - - - - -
EHMLMMCA_03733 2.88e-136 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
EHMLMMCA_03734 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
EHMLMMCA_03735 3.99e-134 ycnI - - S - - - protein conserved in bacteria
EHMLMMCA_03736 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHMLMMCA_03737 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
EHMLMMCA_03738 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EHMLMMCA_03739 2.4e-313 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EHMLMMCA_03740 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EHMLMMCA_03741 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
EHMLMMCA_03742 1.68e-60 ycnE - - S - - - Monooxygenase
EHMLMMCA_03743 2.12e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
EHMLMMCA_03744 1.38e-196 ycnC - - K - - - Transcriptional regulator
EHMLMMCA_03745 0.0 ycnB - - EGP - - - the major facilitator superfamily
EHMLMMCA_03746 2.33e-212 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
EHMLMMCA_03747 5.63e-176 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EHMLMMCA_03748 4.69e-211 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHMLMMCA_03749 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHMLMMCA_03750 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
EHMLMMCA_03751 6.5e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
EHMLMMCA_03752 1.58e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
EHMLMMCA_03754 7.71e-98 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
EHMLMMCA_03755 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
EHMLMMCA_03756 2.23e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHMLMMCA_03757 1.56e-274 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
EHMLMMCA_03758 1.18e-155 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
EHMLMMCA_03759 2.29e-254 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
EHMLMMCA_03760 8.35e-297 gerKC - - S ko:K06297 - ko00000 spore germination
EHMLMMCA_03761 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
EHMLMMCA_03763 0.0 yclG - - M - - - Pectate lyase superfamily protein
EHMLMMCA_03764 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
EHMLMMCA_03765 7.82e-202 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
EHMLMMCA_03766 1.34e-103 yclD - - - - - - -
EHMLMMCA_03767 9.86e-53 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
EHMLMMCA_03768 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
EHMLMMCA_03769 2.24e-140 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
EHMLMMCA_03770 8.83e-208 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
EHMLMMCA_03771 1.23e-187 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
EHMLMMCA_03772 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
EHMLMMCA_03773 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
EHMLMMCA_03774 6.13e-148 yczE - - S ko:K07149 - ko00000 membrane
EHMLMMCA_03775 2.02e-146 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
EHMLMMCA_03776 0.0 ycxD - - K - - - GntR family transcriptional regulator
EHMLMMCA_03777 4.64e-205 ycxC - - EG - - - EamA-like transporter family
EHMLMMCA_03778 3.64e-123 - - - S - - - YcxB-like protein
EHMLMMCA_03779 1.54e-288 - - - EGP - - - Major Facilitator Superfamily
EHMLMMCA_03780 1.63e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
EHMLMMCA_03781 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
EHMLMMCA_03782 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHMLMMCA_03783 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHMLMMCA_03784 6.05e-86 hxlR - - K - - - transcriptional
EHMLMMCA_03785 2.39e-138 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
EHMLMMCA_03786 1.38e-127 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
EHMLMMCA_03787 6.52e-269 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EHMLMMCA_03788 4.78e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
EHMLMMCA_03789 7.06e-93 nin - - S - - - Competence protein J (ComJ)
EHMLMMCA_03790 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EHMLMMCA_03791 3.53e-69 yckD - - S - - - Protein of unknown function (DUF2680)
EHMLMMCA_03792 4.14e-62 yckC - - S - - - membrane
EHMLMMCA_03794 3.76e-187 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
EHMLMMCA_03795 1.22e-148 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
EHMLMMCA_03796 3.22e-289 yciC - - S - - - GTPases (G3E family)
EHMLMMCA_03797 2.97e-131 - - - M - - - ErfK YbiS YcfS YnhG
EHMLMMCA_03798 7.92e-218 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
EHMLMMCA_03799 5.51e-283 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
EHMLMMCA_03800 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
EHMLMMCA_03801 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EHMLMMCA_03802 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EHMLMMCA_03803 3.45e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
EHMLMMCA_03804 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
EHMLMMCA_03805 1.21e-244 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
EHMLMMCA_03806 1.25e-204 ycgS - - I - - - alpha/beta hydrolase fold
EHMLMMCA_03807 1.02e-185 ycgR - - S ko:K07089 - ko00000 permeases
EHMLMMCA_03808 7.72e-195 ycgQ - - S ko:K08986 - ko00000 membrane
EHMLMMCA_03809 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
EHMLMMCA_03810 7.42e-308 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHMLMMCA_03811 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
EHMLMMCA_03812 2.1e-217 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
EHMLMMCA_03813 3.69e-185 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
EHMLMMCA_03814 1.1e-231 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
EHMLMMCA_03815 1.33e-226 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
EHMLMMCA_03816 1.51e-185 - - - Q - - - ubiE/COQ5 methyltransferase family
EHMLMMCA_03817 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EHMLMMCA_03819 3.09e-139 tmrB - - S - - - AAA domain
EHMLMMCA_03820 5.24e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EHMLMMCA_03821 4.4e-144 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
EHMLMMCA_03822 0.0 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
EHMLMMCA_03823 1.85e-195 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
EHMLMMCA_03824 6.42e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
EHMLMMCA_03825 3.7e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
EHMLMMCA_03826 0.0 mdr - - EGP - - - the major facilitator superfamily
EHMLMMCA_03827 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
EHMLMMCA_03828 1.69e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
EHMLMMCA_03829 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
EHMLMMCA_03830 2.72e-105 ycgB - - - - - - -
EHMLMMCA_03831 0.0 ycgA - - S - - - Membrane
EHMLMMCA_03832 1.97e-276 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
EHMLMMCA_03833 2.01e-210 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
EHMLMMCA_03834 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
EHMLMMCA_03835 1.22e-290 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
EHMLMMCA_03836 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
EHMLMMCA_03837 1.07e-263 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
EHMLMMCA_03838 2.7e-278 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
EHMLMMCA_03839 2.96e-245 yceH - - P - - - Belongs to the TelA family
EHMLMMCA_03840 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
EHMLMMCA_03841 1.18e-175 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
EHMLMMCA_03842 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
EHMLMMCA_03843 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
EHMLMMCA_03844 8.84e-140 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
EHMLMMCA_03845 2.42e-237 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHMLMMCA_03846 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
EHMLMMCA_03847 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
EHMLMMCA_03848 2.27e-220 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
EHMLMMCA_03849 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
EHMLMMCA_03850 6.85e-180 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
EHMLMMCA_03851 2.86e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
EHMLMMCA_03852 4.57e-124 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
EHMLMMCA_03853 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EHMLMMCA_03854 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EHMLMMCA_03855 1.35e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
EHMLMMCA_03856 1.29e-182 yccK - - C - - - Aldo keto reductase
EHMLMMCA_03857 2.9e-28 yccK - - C - - - Aldo keto reductase
EHMLMMCA_03858 1.09e-254 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
EHMLMMCA_03859 5.41e-171 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
EHMLMMCA_03860 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
EHMLMMCA_03861 9.8e-210 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
EHMLMMCA_03862 2.49e-255 yccF - - K ko:K07039 - ko00000 SEC-C motif
EHMLMMCA_03863 4.65e-73 - - - S - - - RDD family
EHMLMMCA_03864 4e-147 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
EHMLMMCA_03865 2.06e-258 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
EHMLMMCA_03866 6.54e-132 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
EHMLMMCA_03867 2.51e-302 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
EHMLMMCA_03868 7.39e-254 ycbU - - E - - - Selenocysteine lyase
EHMLMMCA_03869 2.07e-155 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EHMLMMCA_03870 3.61e-158 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EHMLMMCA_03871 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
EHMLMMCA_03872 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
EHMLMMCA_03873 5.44e-174 ycbR - - T - - - vWA found in TerF C terminus
EHMLMMCA_03874 1.82e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
EHMLMMCA_03875 1.82e-75 ycbP - - S - - - Protein of unknown function (DUF2512)
EHMLMMCA_03876 4.75e-147 - - - S - - - ABC-2 family transporter protein
EHMLMMCA_03877 2.64e-213 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHMLMMCA_03878 6.48e-216 ycbM - - T - - - Histidine kinase
EHMLMMCA_03879 3.05e-159 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHMLMMCA_03880 4.43e-131 eamA1 - - EG - - - spore germination
EHMLMMCA_03881 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
EHMLMMCA_03882 6.33e-225 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
EHMLMMCA_03883 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
EHMLMMCA_03884 7.68e-160 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
EHMLMMCA_03885 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
EHMLMMCA_03886 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EHMLMMCA_03887 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EHMLMMCA_03888 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
EHMLMMCA_03889 1.72e-217 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
EHMLMMCA_03890 3.55e-294 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHMLMMCA_03891 9.16e-240 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
EHMLMMCA_03892 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
EHMLMMCA_03893 9.76e-229 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
EHMLMMCA_03894 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EHMLMMCA_03895 3.08e-259 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
EHMLMMCA_03897 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
EHMLMMCA_03898 1.43e-172 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EHMLMMCA_03899 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHMLMMCA_03900 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EHMLMMCA_03901 2.35e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
EHMLMMCA_03902 1.24e-09 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
EHMLMMCA_03903 2.33e-61 ybfN - - - - - - -
EHMLMMCA_03904 4.33e-190 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
EHMLMMCA_03905 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
EHMLMMCA_03906 6.9e-124 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EHMLMMCA_03907 4.76e-215 - - - S - - - Alpha/beta hydrolase family
EHMLMMCA_03909 4.14e-229 mpr - - M - - - Belongs to the peptidase S1B family
EHMLMMCA_03910 1.08e-269 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EHMLMMCA_03911 7.39e-188 ybfI - - K - - - AraC-like ligand binding domain
EHMLMMCA_03912 6.15e-207 ybfH - - EG - - - EamA-like transporter family
EHMLMMCA_03913 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
EHMLMMCA_03915 3.74e-284 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
EHMLMMCA_03916 2.02e-216 ybfA - - K - - - FR47-like protein
EHMLMMCA_03917 1.02e-46 - - - S - - - Protein of unknown function (DUF2651)
EHMLMMCA_03918 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
EHMLMMCA_03919 1.72e-211 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
EHMLMMCA_03920 0.0 ybeC - - E - - - amino acid
EHMLMMCA_03921 1.11e-54 ybyB - - - - - - -
EHMLMMCA_03922 2.67e-314 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
EHMLMMCA_03923 5.85e-29 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
EHMLMMCA_03924 2.18e-132 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
EHMLMMCA_03925 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
EHMLMMCA_03926 5.46e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
EHMLMMCA_03927 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
EHMLMMCA_03928 1.09e-274 ybdO - - S - - - Domain of unknown function (DUF4885)
EHMLMMCA_03929 1.05e-192 ybdN - - - - - - -
EHMLMMCA_03930 4.44e-175 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
EHMLMMCA_03932 1.08e-216 - - - T - - - His Kinase A (phospho-acceptor) domain
EHMLMMCA_03933 2.93e-159 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
EHMLMMCA_03934 1.56e-230 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EHMLMMCA_03935 7.97e-73 - - - - - - - -
EHMLMMCA_03936 7.69e-257 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
EHMLMMCA_03937 9.45e-67 - - - K - - - Helix-turn-helix domain
EHMLMMCA_03938 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
EHMLMMCA_03939 5.59e-64 - - - - - - - -
EHMLMMCA_03941 4.01e-120 ybcF - - P - - - carbonic anhydrase
EHMLMMCA_03942 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
EHMLMMCA_03943 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
EHMLMMCA_03944 1.5e-128 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EHMLMMCA_03945 7.24e-154 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
EHMLMMCA_03946 1.01e-224 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EHMLMMCA_03947 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EHMLMMCA_03948 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EHMLMMCA_03949 1.39e-290 ybbR - - S - - - protein conserved in bacteria
EHMLMMCA_03950 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EHMLMMCA_03951 1.3e-150 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
EHMLMMCA_03952 9.27e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EHMLMMCA_03958 2.43e-100 ybbK - - S - - - Protein of unknown function (DUF523)
EHMLMMCA_03959 3.13e-114 ybbJ - - J - - - acetyltransferase
EHMLMMCA_03960 1.35e-209 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EHMLMMCA_03961 1.82e-192 ybbH - - K - - - transcriptional
EHMLMMCA_03962 2.09e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHMLMMCA_03963 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
EHMLMMCA_03964 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
EHMLMMCA_03965 1.92e-301 ybbC - - S - - - protein conserved in bacteria
EHMLMMCA_03966 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
EHMLMMCA_03967 5.12e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
EHMLMMCA_03968 2.88e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHMLMMCA_03969 2.37e-226 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHMLMMCA_03970 5.87e-177 ybbA - - S ko:K07017 - ko00000 Putative esterase
EHMLMMCA_03971 5.36e-203 ybaS - - S - - - Na -dependent transporter
EHMLMMCA_03973 2.61e-316 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
EHMLMMCA_03974 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EHMLMMCA_03975 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EHMLMMCA_03980 2.4e-76 - - - - - - - -
EHMLMMCA_03982 2.66e-47 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
EHMLMMCA_03983 8.83e-209 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
EHMLMMCA_03984 1.98e-54 - - - - - - - -
EHMLMMCA_03986 1.86e-23 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
EHMLMMCA_03988 3.2e-39 - - - - - - - -
EHMLMMCA_03990 1.88e-21 - - - - - - - -
EHMLMMCA_03991 3.88e-111 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
EHMLMMCA_03992 2.68e-39 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
EHMLMMCA_03993 7.5e-70 - - - K - - - DNA binding
EHMLMMCA_03996 6.54e-35 - - - - - - - -
EHMLMMCA_03998 3.34e-39 - - - L - - - Phage integrase family
EHMLMMCA_04001 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EHMLMMCA_04002 4.31e-181 pdaB - - G - - - Polysaccharide deacetylase
EHMLMMCA_04003 5.95e-133 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
EHMLMMCA_04004 1.04e-122 gerD - - - ko:K06294 - ko00000 -
EHMLMMCA_04005 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
EHMLMMCA_04006 2.22e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
EHMLMMCA_04007 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
EHMLMMCA_04008 2.14e-186 ybaJ - - Q - - - Methyltransferase domain
EHMLMMCA_04009 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
EHMLMMCA_04010 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EHMLMMCA_04011 1.51e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EHMLMMCA_04012 1.6e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EHMLMMCA_04013 1.28e-195 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EHMLMMCA_04014 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EHMLMMCA_04015 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
EHMLMMCA_04016 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EHMLMMCA_04017 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EHMLMMCA_04018 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EHMLMMCA_04019 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
EHMLMMCA_04020 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EHMLMMCA_04021 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
EHMLMMCA_04022 1.46e-156 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EHMLMMCA_04023 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EHMLMMCA_04024 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
EHMLMMCA_04025 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
EHMLMMCA_04026 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EHMLMMCA_04027 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EHMLMMCA_04028 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EHMLMMCA_04029 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EHMLMMCA_04030 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EHMLMMCA_04031 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EHMLMMCA_04032 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EHMLMMCA_04033 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EHMLMMCA_04034 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EHMLMMCA_04035 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
EHMLMMCA_04036 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EHMLMMCA_04037 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EHMLMMCA_04038 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EHMLMMCA_04039 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EHMLMMCA_04040 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EHMLMMCA_04041 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EHMLMMCA_04042 7.98e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
EHMLMMCA_04043 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EHMLMMCA_04044 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
EHMLMMCA_04045 2.04e-227 ybaC - - S - - - Alpha/beta hydrolase family
EHMLMMCA_04046 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EHMLMMCA_04047 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EHMLMMCA_04048 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EHMLMMCA_04049 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EHMLMMCA_04050 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
EHMLMMCA_04051 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EHMLMMCA_04052 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EHMLMMCA_04053 5.1e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
EHMLMMCA_04054 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EHMLMMCA_04055 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EHMLMMCA_04056 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EHMLMMCA_04057 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EHMLMMCA_04058 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
EHMLMMCA_04059 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EHMLMMCA_04060 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
EHMLMMCA_04061 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
EHMLMMCA_04062 3.52e-173 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHMLMMCA_04063 2.04e-95 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EHMLMMCA_04064 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
EHMLMMCA_04065 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
EHMLMMCA_04066 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EHMLMMCA_04067 6.35e-113 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
EHMLMMCA_04068 8.66e-161 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
EHMLMMCA_04069 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
EHMLMMCA_04070 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EHMLMMCA_04071 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EHMLMMCA_04072 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
EHMLMMCA_04073 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
EHMLMMCA_04074 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
EHMLMMCA_04075 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
EHMLMMCA_04076 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EHMLMMCA_04086 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EHMLMMCA_04087 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
EHMLMMCA_04088 1.59e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EHMLMMCA_04089 1.81e-41 yazB - - K - - - transcriptional
EHMLMMCA_04090 4.56e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EHMLMMCA_04091 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EHMLMMCA_04092 6.7e-205 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EHMLMMCA_04093 4.4e-214 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
EHMLMMCA_04094 1.72e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
EHMLMMCA_04095 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EHMLMMCA_04096 4.4e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
EHMLMMCA_04097 2.23e-194 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
EHMLMMCA_04098 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EHMLMMCA_04099 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EHMLMMCA_04100 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EHMLMMCA_04101 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
EHMLMMCA_04102 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EHMLMMCA_04103 1.34e-233 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
EHMLMMCA_04104 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
EHMLMMCA_04105 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
EHMLMMCA_04108 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
EHMLMMCA_04109 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
EHMLMMCA_04110 2.21e-139 yabQ - - S - - - spore cortex biosynthesis protein
EHMLMMCA_04111 1.91e-66 yabP - - S - - - Sporulation protein YabP
EHMLMMCA_04112 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
EHMLMMCA_04113 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
EHMLMMCA_04114 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EHMLMMCA_04115 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
EHMLMMCA_04116 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EHMLMMCA_04117 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
EHMLMMCA_04118 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EHMLMMCA_04119 9.8e-135 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EHMLMMCA_04120 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EHMLMMCA_04121 2.58e-309 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EHMLMMCA_04122 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
EHMLMMCA_04123 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
EHMLMMCA_04124 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
EHMLMMCA_04125 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EHMLMMCA_04126 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
EHMLMMCA_04127 5.32e-53 veg - - S - - - protein conserved in bacteria
EHMLMMCA_04128 1.84e-197 yabG - - S ko:K06436 - ko00000 peptidase
EHMLMMCA_04129 5.04e-199 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EHMLMMCA_04130 1.43e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EHMLMMCA_04131 1.18e-277 yabE - - T - - - protein conserved in bacteria
EHMLMMCA_04132 4.85e-183 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
EHMLMMCA_04133 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHMLMMCA_04134 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
EHMLMMCA_04135 2.95e-207 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EHMLMMCA_04136 4.19e-65 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
EHMLMMCA_04137 2.81e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
EHMLMMCA_04138 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
EHMLMMCA_04139 1.1e-189 yaaT - - S - - - stage 0 sporulation protein
EHMLMMCA_04140 2.42e-236 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
EHMLMMCA_04141 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
EHMLMMCA_04142 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
EHMLMMCA_04143 2.82e-147 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EHMLMMCA_04144 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
EHMLMMCA_04145 8.37e-259 yaaN - - P - - - Belongs to the TelA family
EHMLMMCA_04146 3.28e-133 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
EHMLMMCA_04147 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
EHMLMMCA_04150 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EHMLMMCA_04151 6.2e-48 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
EHMLMMCA_04152 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
EHMLMMCA_04153 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EHMLMMCA_04154 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EHMLMMCA_04155 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EHMLMMCA_04156 1.05e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EHMLMMCA_04157 5.64e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
EHMLMMCA_04158 2.11e-275 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
EHMLMMCA_04159 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
EHMLMMCA_04160 3.72e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
EHMLMMCA_04162 9.79e-296 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EHMLMMCA_04163 6.75e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EHMLMMCA_04164 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EHMLMMCA_04165 3.75e-316 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
EHMLMMCA_04166 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
EHMLMMCA_04167 2.14e-232 yaaC - - S - - - YaaC-like Protein
EHMLMMCA_04170 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EHMLMMCA_04171 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EHMLMMCA_04172 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EHMLMMCA_04173 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
EHMLMMCA_04174 1.85e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EHMLMMCA_04175 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
EHMLMMCA_04176 9.88e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)