ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
CMLPILML_00001 9.37e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CMLPILML_00002 3.82e-191 - - - S - - - Protein of unknown function (DUF1129)
CMLPILML_00003 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
CMLPILML_00004 8.86e-100 ndvA - - V ko:K06147 - ko00000,ko02000 ABC transporter
CMLPILML_00005 1.28e-197 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
CMLPILML_00006 7.1e-177 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
CMLPILML_00007 9.01e-198 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
CMLPILML_00008 2.58e-58 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
CMLPILML_00009 1.09e-79 - - - - - - - -
CMLPILML_00037 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CMLPILML_00038 2.64e-154 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
CMLPILML_00039 3.15e-232 mprF - - S ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CMLPILML_00042 0.0 - - - KL - - - domain protein
CMLPILML_00043 2.2e-195 - - - - - - - -
CMLPILML_00044 0.0 - 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
CMLPILML_00045 2.86e-287 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
CMLPILML_00046 2.91e-229 - - - L - - - Belongs to the 'phage' integrase family
CMLPILML_00047 5.39e-152 - - - V - - - Type I restriction modification DNA specificity domain
CMLPILML_00048 0.0 - 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 EcoEI R protein C-terminal
CMLPILML_00049 0.0 - - - S - - - Protein of unknown function DUF262
CMLPILML_00050 0.0 - - - C - - - FMN_bind
CMLPILML_00051 7.96e-135 - - - - - - - -
CMLPILML_00052 3.51e-142 - - - - - - - -
CMLPILML_00053 8.13e-207 XK27_10395 - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
CMLPILML_00054 1.66e-287 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CMLPILML_00055 1.38e-147 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
CMLPILML_00056 2.31e-196 degV3 - - S - - - Uncharacterised protein, DegV family COG1307
CMLPILML_00057 3.74e-48 yozE - - S - - - Belongs to the UPF0346 family
CMLPILML_00058 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
CMLPILML_00059 4.91e-204 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CMLPILML_00060 7.68e-173 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CMLPILML_00061 1.3e-200 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
CMLPILML_00062 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CMLPILML_00063 1.9e-316 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CMLPILML_00064 1.09e-221 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Phage integrase, N-terminal SAM-like domain
CMLPILML_00065 7.75e-115 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CMLPILML_00066 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CMLPILML_00067 3.03e-231 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
CMLPILML_00068 1.19e-134 - - - K - - - LysR substrate binding domain
CMLPILML_00069 1.17e-129 - - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
CMLPILML_00071 6.86e-92 - - - - - - - -
CMLPILML_00072 1.09e-230 - - - S - - - Conserved hypothetical protein 698
CMLPILML_00073 5.9e-94 - - - K - - - Transcriptional regulator
CMLPILML_00074 6.05e-69 - - - - - - - -
CMLPILML_00075 3.75e-57 - - - - - - - -
CMLPILML_00076 5.57e-55 - - - K ko:K15773 - ko00000,ko02048,ko03000 peptidyl-tyrosine sulfation
CMLPILML_00077 2.08e-179 - - - S - - - PD-(D/E)XK nuclease family transposase
CMLPILML_00078 3.29e-146 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CMLPILML_00079 2.18e-169 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
CMLPILML_00080 6.43e-127 - 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
CMLPILML_00081 3.18e-87 - - - S - - - Protein of unknown function (DUF3021)
CMLPILML_00082 1.27e-99 - - - K - - - LytTr DNA-binding domain
CMLPILML_00083 1.21e-144 ybbB - - S - - - Protein of unknown function (DUF1211)
CMLPILML_00084 0.0 - - - S - - - domain, Protein
CMLPILML_00086 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
CMLPILML_00087 0.0 - - - M - - - domain protein
CMLPILML_00089 0.0 - - - - - - - -
CMLPILML_00090 5.55e-143 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
CMLPILML_00091 2.64e-154 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
CMLPILML_00092 7.35e-103 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
CMLPILML_00093 8.75e-317 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
CMLPILML_00094 1.55e-17 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
CMLPILML_00095 9.19e-21 - - - L - - - Plasmid pRiA4b ORF-3-like protein
CMLPILML_00096 5.79e-90 - - - K - - - HxlR family
CMLPILML_00097 2.79e-64 - - - - - - - -
CMLPILML_00098 1.73e-294 dgoD 4.2.1.6, 4.2.1.8 - M ko:K01684,ko:K08323 ko00040,ko00052,ko01100,ko01120,map00040,map00052,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Mandelate racemase muconate lactonizing enzyme
CMLPILML_00099 1.83e-15 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
CMLPILML_00100 1.13e-98 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
CMLPILML_00101 0.0 - - - P ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter
CMLPILML_00102 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
CMLPILML_00103 3.13e-55 - - - S - - - Cupin domain
CMLPILML_00104 1.41e-242 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
CMLPILML_00105 4.45e-42 - 3.2.1.31 - G ko:K01195 ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 2 family
CMLPILML_00106 2.4e-41 - - - K - - - helix_turn_helix, mercury resistance
CMLPILML_00107 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
CMLPILML_00108 5.26e-157 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
CMLPILML_00109 6.96e-201 - - - C - - - Aldo keto reductase
CMLPILML_00111 1.24e-129 - - - K - - - Transcriptional regulator C-terminal region
CMLPILML_00112 4.43e-296 - - - E - - - Alpha/beta hydrolase of unknown function (DUF1100)
CMLPILML_00113 6.65e-152 - - - GM - - - NAD(P)H-binding
CMLPILML_00114 8.01e-276 mdt(A) - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
CMLPILML_00115 2.78e-80 - - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
CMLPILML_00116 2.7e-43 - - - G ko:K03292 - ko00000 Major facilitator Superfamily
CMLPILML_00117 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
CMLPILML_00118 5.09e-82 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
CMLPILML_00119 4.3e-38 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
CMLPILML_00120 9.67e-222 yobV3 - - K - - - WYL domain
CMLPILML_00121 5.89e-90 - - - S - - - pyridoxamine 5-phosphate
CMLPILML_00122 2.06e-67 - - - K - - - LytTr DNA-binding domain
CMLPILML_00123 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
CMLPILML_00124 9.51e-47 - - - C - - - Heavy-metal-associated domain
CMLPILML_00125 1.13e-125 dpsB - - P - - - Belongs to the Dps family
CMLPILML_00126 1.24e-144 fnr - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
CMLPILML_00127 2.34e-124 - - - K - - - Acetyltransferase (GNAT) family
CMLPILML_00128 7e-114 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
CMLPILML_00129 2.69e-63 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
CMLPILML_00130 1.4e-99 - - - K - - - Transcriptional regulator
CMLPILML_00131 5.33e-90 ogt 2.1.1.63 - L ko:K00567,ko:K07443 - ko00000,ko01000,ko03400 methylated-DNA-[protein]-cysteine S-methyltransferase activity
CMLPILML_00132 2.95e-112 - - - K - - - Acetyltransferase (GNAT) domain
CMLPILML_00133 1.46e-161 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
CMLPILML_00134 1.43e-312 - - - L ko:K07478 - ko00000 AAA C-terminal domain
CMLPILML_00135 2.63e-43 - - - S ko:K07045 - ko00000 Amidohydrolase
CMLPILML_00136 6.34e-135 - - - S ko:K07045 - ko00000 Amidohydrolase
CMLPILML_00137 7.15e-155 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
CMLPILML_00138 3.31e-18 - - - C - - - Aldo/keto reductase family
CMLPILML_00139 6.98e-94 - - - C - - - Aldo/keto reductase family
CMLPILML_00140 1.53e-213 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
CMLPILML_00141 2.95e-160 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
CMLPILML_00142 1.4e-148 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
CMLPILML_00143 5.23e-151 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CMLPILML_00144 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CMLPILML_00145 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CMLPILML_00146 2.92e-231 - - - K - - - Transcriptional regulator
CMLPILML_00147 3.5e-220 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
CMLPILML_00148 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
CMLPILML_00149 6.77e-142 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CMLPILML_00150 1.5e-161 - - - S - - - Protein of unknown function (DUF1275)
CMLPILML_00151 6.93e-261 xerS - - L ko:K03733 - ko00000,ko03036 Belongs to the 'phage' integrase family
CMLPILML_00152 2.76e-214 lysR - - K - - - Transcriptional regulator
CMLPILML_00153 3.45e-197 - - - - - - - -
CMLPILML_00154 1.93e-209 - - - S - - - EDD domain protein, DegV family
CMLPILML_00155 5.72e-85 - - - - - - - -
CMLPILML_00156 0.0 FbpA - - K - - - Fibronectin-binding protein
CMLPILML_00157 0.0 carB1 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
CMLPILML_00158 4.62e-252 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
CMLPILML_00159 1.01e-220 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
CMLPILML_00160 9.07e-102 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CMLPILML_00161 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
CMLPILML_00162 2.74e-77 - - - - - - - -
CMLPILML_00163 7.03e-224 degV1 - - S - - - DegV family
CMLPILML_00164 1.52e-305 cpdA - - S - - - Calcineurin-like phosphoesterase
CMLPILML_00165 1.61e-275 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
CMLPILML_00166 1.37e-94 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CMLPILML_00167 2.28e-137 ypsA - - S - - - Belongs to the UPF0398 family
CMLPILML_00168 2.82e-153 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CMLPILML_00169 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
CMLPILML_00170 6.69e-149 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CMLPILML_00171 2.06e-150 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
CMLPILML_00172 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
CMLPILML_00173 5.37e-117 ypmB - - S - - - Protein conserved in bacteria
CMLPILML_00174 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
CMLPILML_00175 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
CMLPILML_00176 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
CMLPILML_00177 1.8e-214 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
CMLPILML_00178 1.67e-223 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
CMLPILML_00179 2.53e-260 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
CMLPILML_00180 2.24e-238 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CMLPILML_00181 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
CMLPILML_00182 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
CMLPILML_00183 4.73e-203 - 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 Aminoglycoside 3-N-acetyltransferase
CMLPILML_00184 2e-207 rbsU - - U ko:K06216 - ko00000,ko02000 ribose uptake protein RbsU
CMLPILML_00185 5.83e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
CMLPILML_00186 1.79e-110 - - - S - - - ASCH
CMLPILML_00187 1.45e-173 - - - F - - - Phosphorylase superfamily
CMLPILML_00188 4.43e-115 - 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 Acetyltransferase (GNAT) family
CMLPILML_00189 1.1e-129 rimL - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
CMLPILML_00190 2.21e-57 - - - - ko:K07473 - ko00000,ko02048 -
CMLPILML_00191 6.11e-68 - - - S ko:K19157 - ko00000,ko01000,ko02048 endonuclease activity
CMLPILML_00192 1.76e-193 - - - S - - - Fic/DOC family
CMLPILML_00193 4.3e-185 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
CMLPILML_00194 3.65e-54 - - - - - - - -
CMLPILML_00195 1.39e-174 - - - - - - - -
CMLPILML_00196 1.28e-82 - - - - - - - -
CMLPILML_00197 9.1e-65 - - - S - - - MazG-like family
CMLPILML_00198 7.8e-196 - - - S - - - Protein of unknown function (DUF2785)
CMLPILML_00199 2.25e-31 - - - K - - - Acetyltransferase (GNAT) domain
CMLPILML_00200 1.43e-48 - - - K - - - Acetyltransferase (GNAT) domain
CMLPILML_00201 2.39e-64 - - - - - - - -
CMLPILML_00202 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
CMLPILML_00203 1.01e-110 yfhC - - C - - - nitroreductase
CMLPILML_00204 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
CMLPILML_00205 5.46e-193 - - - K - - - Helix-turn-helix domain
CMLPILML_00206 1.1e-181 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
CMLPILML_00207 2.21e-186 - - - S - - - Protein of unknown function (DUF975)
CMLPILML_00208 8.4e-74 - - - K - - - sequence-specific DNA binding
CMLPILML_00210 2.05e-136 yokL3 - - J - - - Acetyltransferase (GNAT) domain
CMLPILML_00211 1.15e-179 - - - - - - - -
CMLPILML_00212 0.0 XK27_00340 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
CMLPILML_00213 1.5e-56 - - - G - - - Ribose/Galactose Isomerase
CMLPILML_00214 1.42e-66 - - - - - - - -
CMLPILML_00215 1.81e-38 - - - - - - - -
CMLPILML_00216 1.57e-152 - - - C - - - nitroreductase
CMLPILML_00217 0.0 - - - C - - - FMN_bind
CMLPILML_00218 8.2e-214 - - - K - - - LysR substrate binding domain
CMLPILML_00219 9.14e-204 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CMLPILML_00220 1.75e-294 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
CMLPILML_00221 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
CMLPILML_00222 5.21e-254 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CMLPILML_00223 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
CMLPILML_00224 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
CMLPILML_00225 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
CMLPILML_00226 6.34e-165 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CMLPILML_00227 1.11e-163 alkD - - L - - - DNA alkylation repair enzyme
CMLPILML_00228 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CMLPILML_00229 1.02e-136 pncA - - Q - - - Isochorismatase family
CMLPILML_00230 4.14e-121 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CMLPILML_00231 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
CMLPILML_00232 2.26e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
CMLPILML_00233 3.11e-308 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CMLPILML_00234 6.42e-237 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
CMLPILML_00235 2.9e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CMLPILML_00236 2.34e-217 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CMLPILML_00237 2.49e-166 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CMLPILML_00238 1.11e-153 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CMLPILML_00239 0.0 - - - I - - - Protein of unknown function (DUF2974)
CMLPILML_00240 4.51e-197 yxeH - - S - - - hydrolase
CMLPILML_00241 2.48e-215 - - - S - - - DUF218 domain
CMLPILML_00242 7.47e-70 ybjQ - - S - - - Belongs to the UPF0145 family
CMLPILML_00243 2.49e-297 rsmF - - J - - - NOL1 NOP2 sun family protein
CMLPILML_00244 8.88e-221 - - - - - - - -
CMLPILML_00245 2.2e-171 - - - - - - - -
CMLPILML_00246 1.27e-134 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
CMLPILML_00247 1.45e-30 - - - - - - - -
CMLPILML_00248 1.55e-140 - - - - - - - -
CMLPILML_00249 6.56e-185 - - - - - - - -
CMLPILML_00250 1.46e-160 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
CMLPILML_00251 2.1e-78 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
CMLPILML_00252 1.88e-313 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
CMLPILML_00253 1.15e-195 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CMLPILML_00254 3.7e-155 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
CMLPILML_00255 2.29e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CMLPILML_00256 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CMLPILML_00257 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
CMLPILML_00258 1.82e-228 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
CMLPILML_00259 4.14e-177 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
CMLPILML_00260 4.24e-217 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CMLPILML_00261 4.52e-128 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CMLPILML_00262 1.67e-222 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
CMLPILML_00263 3.98e-79 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
CMLPILML_00264 8.33e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
CMLPILML_00265 5.46e-200 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
CMLPILML_00266 1.71e-206 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
CMLPILML_00267 1.53e-139 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CMLPILML_00268 4.33e-185 - - - E - - - GDSL-like Lipase/Acylhydrolase family
CMLPILML_00269 1.14e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
CMLPILML_00270 3.88e-284 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
CMLPILML_00271 1e-43 - - - - - - - -
CMLPILML_00272 2.52e-210 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Peptidase family M48
CMLPILML_00274 1.33e-99 - - - S - - - HIRAN
CMLPILML_00275 1.33e-09 licB2 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
CMLPILML_00276 1.53e-243 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
CMLPILML_00277 3.48e-152 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
CMLPILML_00278 1.66e-214 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CMLPILML_00279 5e-268 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CMLPILML_00280 1.3e-286 - - - KQ - - - helix_turn_helix, mercury resistance
CMLPILML_00281 5.27e-235 - - - V - - - Abi-like protein
CMLPILML_00282 2.28e-31 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
CMLPILML_00283 7.2e-235 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
CMLPILML_00284 4.11e-229 - - - S - - - Acyltransferase family
CMLPILML_00285 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
CMLPILML_00286 1.1e-281 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
CMLPILML_00287 1.08e-270 - - - - - - - -
CMLPILML_00288 7.35e-249 - - - M - - - Glycosyl transferase family 2
CMLPILML_00289 5.88e-256 - - - M - - - transferase activity, transferring glycosyl groups
CMLPILML_00290 6.33e-254 - - - M - - - Glycosyl transferases group 1
CMLPILML_00291 4.29e-207 - - GT2 S ko:K12990 ko02024,ko02025,map02024,map02025 ko00000,ko00001,ko01000,ko01003,ko01005 Glycosyl transferase family 2
CMLPILML_00292 5.28e-237 - - - H - - - Glycosyl transferase family 11
CMLPILML_00293 3.49e-160 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
CMLPILML_00294 2.18e-117 - - - S - - - Glycosyltransferase family 28 C-terminal domain
CMLPILML_00295 1.21e-108 - - - M - - - Oligosaccharide biosynthesis protein Alg14 like
CMLPILML_00296 2.06e-157 epsE2 - - M - - - Bacterial sugar transferase
CMLPILML_00297 5.69e-187 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
CMLPILML_00298 3.3e-162 ywqD - - D - - - Capsular exopolysaccharide family
CMLPILML_00299 5.62e-193 epsB - - M - - - biosynthesis protein
CMLPILML_00300 5.1e-220 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
CMLPILML_00301 2.58e-103 - - - K - - - DNA-templated transcription, initiation
CMLPILML_00302 1.12e-212 - - - - - - - -
CMLPILML_00303 3.15e-158 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
CMLPILML_00304 6.2e-302 - - - - - - - -
CMLPILML_00305 4.05e-102 - - - S - - - Domain of unknown function (DUF4767)
CMLPILML_00306 1.29e-107 - - - - - - - -
CMLPILML_00307 3.98e-116 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CMLPILML_00308 5.34e-134 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
CMLPILML_00309 2.5e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CMLPILML_00310 1.79e-278 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CMLPILML_00311 6.94e-288 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CMLPILML_00312 2e-206 - - - - - - - -
CMLPILML_00313 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CMLPILML_00314 1.44e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CMLPILML_00315 1.97e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
CMLPILML_00316 1.23e-229 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
CMLPILML_00317 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
CMLPILML_00318 5.23e-132 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
CMLPILML_00319 1.45e-236 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
CMLPILML_00320 5.77e-113 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CMLPILML_00321 7.11e-124 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
CMLPILML_00322 7.67e-69 ylbG - - S - - - UPF0298 protein
CMLPILML_00323 1.66e-269 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
CMLPILML_00324 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
CMLPILML_00325 2.39e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CMLPILML_00326 1.53e-47 ykzG - - S - - - Belongs to the UPF0356 family
CMLPILML_00327 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CMLPILML_00328 5.63e-226 ytlR - - I - - - Diacylglycerol kinase catalytic domain
CMLPILML_00329 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CMLPILML_00330 2.93e-150 - - - S - - - repeat protein
CMLPILML_00331 4.52e-161 pgm - - G - - - Phosphoglycerate mutase family
CMLPILML_00332 3e-278 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CMLPILML_00333 1.8e-76 XK27_04120 - - S - - - Putative amino acid metabolism
CMLPILML_00334 4.29e-276 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
CMLPILML_00335 1.68e-163 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CMLPILML_00336 1.22e-23 - - - - - - - -
CMLPILML_00337 3.65e-133 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
CMLPILML_00338 3.24e-44 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
CMLPILML_00339 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CMLPILML_00340 2.05e-163 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
CMLPILML_00341 3.41e-188 ylmH - - S - - - S4 domain protein
CMLPILML_00342 1.93e-47 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
CMLPILML_00343 4.43e-95 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
CMLPILML_00344 7.39e-309 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CMLPILML_00345 2.81e-313 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CMLPILML_00346 4.13e-197 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CMLPILML_00347 2.01e-267 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CMLPILML_00348 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CMLPILML_00349 1.82e-226 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CMLPILML_00350 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
CMLPILML_00351 3.95e-73 ftsL - - D - - - Cell division protein FtsL
CMLPILML_00352 7.69e-226 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CMLPILML_00353 1.33e-100 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
CMLPILML_00354 7.67e-69 - - - S - - - Protein of unknown function (DUF3397)
CMLPILML_00355 1.66e-19 - - - S - - - Protein of unknown function (DUF4044)
CMLPILML_00356 9.8e-124 mreD - - - ko:K03571 - ko00000,ko03036 -
CMLPILML_00357 2.88e-189 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
CMLPILML_00358 2.19e-225 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
CMLPILML_00359 5.06e-144 radC - - L ko:K03630 - ko00000 DNA repair protein
CMLPILML_00360 1.56e-160 - - - S - - - Haloacid dehalogenase-like hydrolase
CMLPILML_00361 5.72e-301 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
CMLPILML_00362 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CMLPILML_00363 0.0 yoaB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
CMLPILML_00364 4.76e-269 - - - C - - - Glycerophosphoryl diester phosphodiesterase family
CMLPILML_00365 7.16e-161 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
CMLPILML_00366 2.67e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CMLPILML_00367 4.29e-276 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
CMLPILML_00368 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CMLPILML_00370 7.54e-143 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CMLPILML_00371 1.21e-106 - - - S - - - Protein of unknown function (DUF1694)
CMLPILML_00372 3.11e-307 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
CMLPILML_00373 2.34e-08 - - - - - - - -
CMLPILML_00374 3.9e-106 uspA - - T - - - universal stress protein
CMLPILML_00375 3.34e-287 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
CMLPILML_00376 3.08e-47 - - - S - - - Protein of unknown function (DUF2969)
CMLPILML_00377 6.72e-70 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
CMLPILML_00378 2.97e-21 - - - S - - - DNA-directed RNA polymerase subunit beta
CMLPILML_00379 1.01e-228 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
CMLPILML_00380 3e-41 - - - S - - - Protein of unknown function (DUF1146)
CMLPILML_00381 3.48e-93 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
CMLPILML_00382 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CMLPILML_00383 2.1e-220 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CMLPILML_00384 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CMLPILML_00385 7.97e-121 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CMLPILML_00386 1.96e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CMLPILML_00387 9.31e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CMLPILML_00388 1.43e-162 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
CMLPILML_00389 2.24e-147 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CMLPILML_00390 9.87e-242 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CMLPILML_00391 7.54e-204 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CMLPILML_00392 1.27e-250 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CMLPILML_00393 5.77e-145 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
CMLPILML_00394 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain
CMLPILML_00395 2.07e-249 ampC - - V - - - Beta-lactamase
CMLPILML_00398 2.98e-94 - - - - - - - -
CMLPILML_00399 6.39e-141 - - - EGP - - - Major Facilitator
CMLPILML_00400 2.79e-108 - - - EGP - - - Major Facilitator
CMLPILML_00401 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
CMLPILML_00402 1.93e-139 vanZ - - V - - - VanZ like family
CMLPILML_00403 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CMLPILML_00404 0.0 yclK - - T - - - Histidine kinase
CMLPILML_00405 6.61e-167 - - - K - - - Transcriptional regulatory protein, C terminal
CMLPILML_00406 9.78e-89 - - - S - - - SdpI/YhfL protein family
CMLPILML_00407 7.57e-245 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
CMLPILML_00408 1.62e-100 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
CMLPILML_00409 4.11e-105 - - - M - - - Protein of unknown function (DUF3737)
CMLPILML_00410 8.38e-36 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Levansucrase/Invertase
CMLPILML_00411 1.27e-220 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Levansucrase/Invertase
CMLPILML_00416 3.1e-276 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CMLPILML_00417 0.0 mdr - - EGP - - - Major Facilitator
CMLPILML_00418 1.7e-164 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
CMLPILML_00419 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
CMLPILML_00420 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
CMLPILML_00421 1.82e-278 - - - I - - - Protein of unknown function (DUF2974)
CMLPILML_00422 2.27e-164 - - - - - - - -
CMLPILML_00423 1.32e-192 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CMLPILML_00424 1.96e-161 - - - M - - - ErfK YbiS YcfS YnhG
CMLPILML_00425 5.83e-222 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
CMLPILML_00426 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
CMLPILML_00427 3.12e-220 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
CMLPILML_00428 4.75e-67 - - - - - - - -
CMLPILML_00429 4.65e-100 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
CMLPILML_00430 3.38e-76 - - - S - - - Antibiotic biosynthesis monooxygenase
CMLPILML_00432 3.04e-123 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
CMLPILML_00433 3.72e-166 - - - F - - - Glutamine amidotransferase class-I
CMLPILML_00434 9.45e-145 ylbE - - GM - - - NAD(P)H-binding
CMLPILML_00435 2.16e-108 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
CMLPILML_00436 8.55e-247 - - - S - - - Bacteriocin helveticin-J
CMLPILML_00437 4.71e-139 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
CMLPILML_00438 3.31e-212 - - - S ko:K07088 - ko00000 Membrane transport protein
CMLPILML_00439 4.43e-177 - - - S ko:K07052 - ko00000 CAAX amino terminal protease
CMLPILML_00440 5.44e-187 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
CMLPILML_00441 0.0 qacA - - EGP - - - Major Facilitator
CMLPILML_00442 9.29e-182 qacA - - EGP - - - Major Facilitator
CMLPILML_00443 8.38e-126 qacA - - EGP - - - Major Facilitator
CMLPILML_00444 5.51e-123 - - - K - - - Bacterial regulatory proteins, tetR family
CMLPILML_00445 0.0 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
CMLPILML_00446 4.48e-102 - - - K - - - acetyltransferase
CMLPILML_00447 1.57e-187 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
CMLPILML_00448 4.86e-134 - - - S - - - Protein of unknown function (DUF1440)
CMLPILML_00449 1.99e-193 - - - S - - - hydrolase
CMLPILML_00450 1.44e-98 - - - K - - - Transcriptional regulator
CMLPILML_00451 2.78e-79 - - - K - - - Transcriptional regulator
CMLPILML_00452 2.57e-307 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
CMLPILML_00453 2.29e-176 - - - K ko:K02530 - ko00000,ko03000 DeoR C terminal sensor domain
CMLPILML_00454 9.37e-96 lacA 5.3.1.26 - G ko:K01819 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 Ribose/Galactose Isomerase
CMLPILML_00455 2.86e-137 - 5.3.1.26 - G ko:K01819 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 Ribose/Galactose Isomerase
CMLPILML_00456 5.07e-166 - - - S - - - Domain of unknown function (DUF4867)
CMLPILML_00457 1.71e-111 - 2.7.1.204 - G ko:K20112 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CMLPILML_00458 6.32e-68 - 2.7.1.204 - G ko:K20113 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
CMLPILML_00459 0.0 gatC - - G ko:K20114 ko02060,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
CMLPILML_00460 3.59e-52 - - - - - - - -
CMLPILML_00461 1.19e-195 lacT - - K ko:K02531 - ko00000,ko03000 CAT RNA binding domain
CMLPILML_00462 6.12e-76 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
CMLPILML_00463 0.0 lacE 2.7.1.207 - G ko:K02787,ko:K02788 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system, EIIC
CMLPILML_00464 0.0 lacG 3.2.1.21, 3.2.1.85 - G ko:K01220,ko:K05350 ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
CMLPILML_00465 3.04e-258 - - - S - - - PFAM Archaeal ATPase
CMLPILML_00466 1.31e-211 - - - K - - - LysR family
CMLPILML_00467 0.0 - - - C - - - FMN_bind
CMLPILML_00468 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
CMLPILML_00469 1.08e-216 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
CMLPILML_00470 1.23e-144 - - - I - - - Acid phosphatase homologues
CMLPILML_00471 2.3e-276 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
CMLPILML_00472 7.95e-45 - - - - - - - -
CMLPILML_00473 4.11e-95 rmaE - - K - - - helix_turn_helix multiple antibiotic resistance protein
CMLPILML_00474 1.64e-108 - - - - - - - -
CMLPILML_00475 5.75e-267 pepA - - E - - - M42 glutamyl aminopeptidase
CMLPILML_00477 5.16e-115 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
CMLPILML_00478 1.4e-155 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
CMLPILML_00479 1.49e-194 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
CMLPILML_00480 2.38e-94 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
CMLPILML_00481 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
CMLPILML_00482 5.45e-232 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
CMLPILML_00483 0.0 - 3.2.1.177 GH31 G ko:K01811 - ko00000,ko01000 Glycosyl hydrolases family 31
CMLPILML_00484 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
CMLPILML_00485 2.81e-265 - - - EGP ko:K08196 - ko00000,ko02000 Major Facilitator
CMLPILML_00486 2.6e-202 - - - S - - - Alpha beta hydrolase
CMLPILML_00487 2.27e-98 - - - K - - - Transcriptional regulator, MarR family
CMLPILML_00488 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
CMLPILML_00489 0.0 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
CMLPILML_00490 6.61e-190 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
CMLPILML_00491 4.37e-176 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
CMLPILML_00492 1.18e-191 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
CMLPILML_00493 1.5e-142 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
CMLPILML_00494 7.95e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
CMLPILML_00495 1.77e-199 - - - S - - - PD-(D/E)XK nuclease family transposase
CMLPILML_00496 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
CMLPILML_00497 3.51e-167 treR - - K ko:K03486 - ko00000,ko03000 UTRA
CMLPILML_00498 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CMLPILML_00499 1.16e-128 - - - S - - - Putative adhesin
CMLPILML_00500 9.28e-146 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
CMLPILML_00501 9.09e-204 - - - EGP - - - Major facilitator superfamily
CMLPILML_00502 9.4e-100 - - - EGP - - - Major facilitator superfamily
CMLPILML_00504 7.42e-75 - - - S - - - Enterocin A Immunity
CMLPILML_00505 0.0 pacL - - P - - - Cation transporter/ATPase, N-terminus
CMLPILML_00506 1.36e-207 - - - S - - - Phospholipase, patatin family
CMLPILML_00507 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
CMLPILML_00508 2.68e-170 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
CMLPILML_00509 2.8e-124 - - - K - - - Acetyltransferase (GNAT) domain
CMLPILML_00510 2.89e-206 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
CMLPILML_00511 1.24e-216 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
CMLPILML_00512 2.05e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
CMLPILML_00513 3.84e-190 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CMLPILML_00514 2.13e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CMLPILML_00515 4.1e-152 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
CMLPILML_00516 0.0 - - - S - - - C4-dicarboxylate anaerobic carrier
CMLPILML_00517 1.15e-109 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
CMLPILML_00519 1.58e-212 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CMLPILML_00520 8.05e-166 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CMLPILML_00521 5.75e-224 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
CMLPILML_00522 2.4e-172 gntR - - K - - - UbiC transcription regulator-associated domain protein
CMLPILML_00523 7.47e-70 - - - S - - - Enterocin A Immunity
CMLPILML_00524 3.92e-178 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
CMLPILML_00525 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
CMLPILML_00526 1.24e-153 - - - C - - - nitroreductase
CMLPILML_00527 8.05e-171 - - - - - - - -
CMLPILML_00528 0.0 yhdP - - S - - - Transporter associated domain
CMLPILML_00529 1.22e-132 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
CMLPILML_00530 2.29e-299 - - - E ko:K03294 - ko00000 amino acid
CMLPILML_00531 3.55e-176 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
CMLPILML_00532 1.35e-278 yfmL - - L - - - DEAD DEAH box helicase
CMLPILML_00533 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMLPILML_00536 1.64e-277 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
CMLPILML_00537 3.13e-113 gtcA1 - - S - - - Teichoic acid glycosylation protein
CMLPILML_00538 4.75e-101 ykuP - - C ko:K03839 - ko00000 Flavodoxin
CMLPILML_00539 2.09e-207 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
CMLPILML_00540 6.47e-214 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
CMLPILML_00541 1.94e-217 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
CMLPILML_00542 3.18e-199 - - - S - - - PD-(D/E)XK nuclease family transposase
CMLPILML_00543 1.02e-230 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
CMLPILML_00544 0.0 - - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
CMLPILML_00545 4.54e-91 - - - O - - - OsmC-like protein
CMLPILML_00546 1.52e-28 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
CMLPILML_00547 2.97e-149 - - - T - - - Region found in RelA / SpoT proteins
CMLPILML_00548 1.44e-149 dltr - - K - - - response regulator
CMLPILML_00549 3.86e-300 sptS - - T - - - Histidine kinase
CMLPILML_00550 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
CMLPILML_00551 2.75e-74 - - - - - - - -
CMLPILML_00552 8.93e-90 - - - - - - - -
CMLPILML_00553 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
CMLPILML_00554 1.1e-184 - - - S - - - haloacid dehalogenase-like hydrolase
CMLPILML_00555 1.13e-158 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
CMLPILML_00557 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CMLPILML_00558 2.46e-95 - - - - - - - -
CMLPILML_00559 6.22e-140 - - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
CMLPILML_00560 1.78e-289 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
CMLPILML_00561 5.65e-277 - - - S - - - Phage integrase family
CMLPILML_00563 5.91e-41 - - - S - - - Domain of unknown function (DUF4393)
CMLPILML_00564 4.99e-48 - - - - - - - -
CMLPILML_00565 2.19e-155 - - - V - - - Abi-like protein
CMLPILML_00567 8.78e-26 - - - S - - - Domain of unknown function (DUF4145)
CMLPILML_00569 1.3e-91 - - - K - - - Peptidase S24-like
CMLPILML_00572 1.15e-22 - - - K - - - Helix-turn-helix XRE-family like proteins
CMLPILML_00573 1.18e-25 - - - K - - - Helix-turn-helix XRE-family like proteins
CMLPILML_00576 1.86e-133 - - - K ko:K07741 - ko00000 BRO family, N-terminal domain
CMLPILML_00577 2.81e-40 - - - - - - - -
CMLPILML_00580 7.4e-23 - - - - - - - -
CMLPILML_00582 1.71e-41 - - - - - - - -
CMLPILML_00585 1.84e-129 - - - L - - - Psort location Cytoplasmic, score
CMLPILML_00590 9.73e-20 - - - L - - - Belongs to the 'phage' integrase family
CMLPILML_00591 1.82e-32 - - - - - - - -
CMLPILML_00600 1.16e-102 - - - S - - - Phage transcriptional regulator, ArpU family
CMLPILML_00601 1.11e-112 - - - S - - - HNH endonuclease
CMLPILML_00602 2.09e-85 - - - L - - - Phage terminase, small subunit
CMLPILML_00603 3.76e-51 yoeB - - S ko:K19158 - ko00000,ko01000,ko02048 YoeB-like toxin of bacterial type II toxin-antitoxin system
CMLPILML_00604 2.31e-48 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
CMLPILML_00605 1.58e-305 - - - S - - - Phage Terminase
CMLPILML_00607 1.91e-204 - - - S - - - Phage portal protein
CMLPILML_00608 4.39e-144 - - - S - - - Clp protease
CMLPILML_00609 2.92e-248 - - - S - - - Phage capsid family
CMLPILML_00610 1.47e-52 - - - S - - - Phage gp6-like head-tail connector protein
CMLPILML_00616 0.0 - - - L - - - Phage tail tape measure protein TP901
CMLPILML_00617 9.36e-152 - - - S - - - Phage tail protein
CMLPILML_00618 1.94e-241 - - - S - - - Phage minor structural protein
CMLPILML_00619 4.62e-67 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
CMLPILML_00625 3.38e-134 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
CMLPILML_00626 6.07e-14 - - - - - - - -
CMLPILML_00627 2.83e-165 pnb - - C - - - nitroreductase
CMLPILML_00628 5.18e-128 - - - S - - - Domain of unknown function (DUF4811)
CMLPILML_00629 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
CMLPILML_00630 4.6e-102 - - - K - - - MerR HTH family regulatory protein
CMLPILML_00631 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
CMLPILML_00632 6.93e-81 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
CMLPILML_00633 0.0 pepC4 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
CMLPILML_00634 7.29e-215 - - - GK - - - ROK family
CMLPILML_00635 1.12e-211 - - - K - - - helix_turn_helix, arabinose operon control protein
CMLPILML_00636 8.33e-225 - - - I - - - Carboxylesterase family
CMLPILML_00637 2.31e-264 - - - P - - - Major Facilitator Superfamily
CMLPILML_00638 0.0 - - - S - - - Predicted membrane protein (DUF2207)
CMLPILML_00639 4.63e-74 - - - K - - - Acetyltransferase (GNAT) domain
CMLPILML_00640 1.59e-77 - - - - - - - -
CMLPILML_00641 3.41e-193 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
CMLPILML_00642 4.96e-121 - - - S - - - ECF-type riboflavin transporter, S component
CMLPILML_00643 4.18e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
CMLPILML_00644 4.08e-18 - - - - - - - -
CMLPILML_00645 2.59e-313 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
CMLPILML_00646 1.89e-192 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
CMLPILML_00647 1.23e-84 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
CMLPILML_00648 1.67e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
CMLPILML_00649 9.89e-64 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
CMLPILML_00650 1.56e-257 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
CMLPILML_00651 6.05e-133 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CMLPILML_00652 1.47e-95 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
CMLPILML_00653 1.42e-88 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CMLPILML_00654 2.23e-197 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CMLPILML_00655 0.0 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CMLPILML_00656 1.93e-46 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CMLPILML_00657 1.71e-204 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
CMLPILML_00658 1.85e-199 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
CMLPILML_00659 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
CMLPILML_00660 8.55e-64 - - - - - - - -
CMLPILML_00661 5.97e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
CMLPILML_00662 1.63e-43 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
CMLPILML_00663 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CMLPILML_00664 8.3e-225 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CMLPILML_00665 1.55e-310 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CMLPILML_00666 2.6e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
CMLPILML_00667 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
CMLPILML_00668 9.56e-211 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CMLPILML_00669 1.11e-155 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
CMLPILML_00670 4.49e-158 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
CMLPILML_00671 9.04e-34 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
CMLPILML_00672 8.29e-75 yloU - - S - - - Asp23 family, cell envelope-related function
CMLPILML_00673 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
CMLPILML_00674 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CMLPILML_00675 1.01e-234 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CMLPILML_00676 6.2e-48 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
CMLPILML_00677 4.35e-244 oppD - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CMLPILML_00678 2.91e-229 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CMLPILML_00679 3.16e-232 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
CMLPILML_00680 2.73e-209 oppC5 - - P ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
CMLPILML_00681 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
CMLPILML_00682 2.49e-261 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
CMLPILML_00683 3.29e-110 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
CMLPILML_00684 5.24e-159 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CMLPILML_00685 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
CMLPILML_00686 1.78e-241 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CMLPILML_00687 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
CMLPILML_00688 2.45e-75 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CMLPILML_00689 4.67e-290 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CMLPILML_00690 1.37e-59 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
CMLPILML_00691 8.79e-125 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CMLPILML_00692 3.13e-175 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
CMLPILML_00693 2.61e-76 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CMLPILML_00694 3.68e-151 sipS3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
CMLPILML_00695 1.68e-98 apfA 3.6.1.61 - F ko:K18445 ko00230,map00230 ko00000,ko00001,ko01000 Nudix hydrolase
CMLPILML_00696 1.35e-149 ung2 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
CMLPILML_00697 3.88e-147 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CMLPILML_00698 9.78e-46 ynzC - - S - - - UPF0291 protein
CMLPILML_00699 3.41e-41 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
CMLPILML_00700 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
CMLPILML_00701 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
CMLPILML_00702 1.31e-286 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
CMLPILML_00703 3.62e-151 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
CMLPILML_00704 1.87e-249 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
CMLPILML_00705 1.07e-180 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
CMLPILML_00706 4.15e-234 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CMLPILML_00707 7.13e-169 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
CMLPILML_00708 2.87e-120 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CMLPILML_00709 1.7e-175 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CMLPILML_00710 3.37e-178 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
CMLPILML_00711 3.14e-293 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
CMLPILML_00712 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CMLPILML_00713 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CMLPILML_00714 2.25e-107 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
CMLPILML_00715 6.72e-277 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
CMLPILML_00716 2.17e-62 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
CMLPILML_00717 2.2e-62 - - - J - - - ribosomal protein
CMLPILML_00718 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CMLPILML_00719 6.74e-80 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CMLPILML_00720 2.1e-214 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CMLPILML_00721 4.29e-226 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
CMLPILML_00722 0.0 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
CMLPILML_00723 1.71e-155 - - - S - - - GyrI-like small molecule binding domain
CMLPILML_00724 4.59e-248 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CMLPILML_00725 9.65e-111 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CMLPILML_00726 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
CMLPILML_00727 9.97e-252 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CMLPILML_00728 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CMLPILML_00729 6.6e-159 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
CMLPILML_00730 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
CMLPILML_00731 1.02e-124 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CMLPILML_00732 0.0 potE - - E - - - Amino Acid
CMLPILML_00733 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CMLPILML_00734 1.21e-244 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CMLPILML_00735 3.2e-126 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CMLPILML_00736 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
CMLPILML_00737 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
CMLPILML_00738 4.36e-204 lysR5 - - K - - - LysR substrate binding domain
CMLPILML_00740 5.12e-132 - - - I - - - PAP2 superfamily
CMLPILML_00741 6.08e-312 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CMLPILML_00742 9.84e-41 - - - S - - - Sugar efflux transporter for intercellular exchange
CMLPILML_00743 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
CMLPILML_00744 4.03e-64 - - - K - - - Helix-turn-helix domain
CMLPILML_00745 1.33e-194 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
CMLPILML_00746 5.81e-125 - - - L - - - nuclease
CMLPILML_00747 5.71e-201 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
CMLPILML_00748 9.17e-242 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CMLPILML_00749 2.57e-126 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
CMLPILML_00750 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
CMLPILML_00751 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
CMLPILML_00752 1.54e-217 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
CMLPILML_00753 0.0 - - - S - - - Putative threonine/serine exporter
CMLPILML_00754 4.36e-242 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
CMLPILML_00755 0.0 aha1 - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
CMLPILML_00756 0.0 - - - S - - - Bacterial membrane protein, YfhO
CMLPILML_00757 1.7e-113 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CMLPILML_00758 4.27e-223 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
CMLPILML_00759 2.32e-86 - - - - - - - -
CMLPILML_00760 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CMLPILML_00761 2.88e-96 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CMLPILML_00762 4.28e-312 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
CMLPILML_00763 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
CMLPILML_00764 3.8e-118 - - - - - - - -
CMLPILML_00765 1.22e-107 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
CMLPILML_00766 3.4e-58 - - - - - - - -
CMLPILML_00767 2.11e-89 - - - - - - - -
CMLPILML_00768 4.27e-85 - - - S - - - Domain of unknown function DUF1828
CMLPILML_00769 2.98e-140 - - - S - - - Rib/alpha-like repeat
CMLPILML_00770 4.62e-316 yagE - - E - - - amino acid
CMLPILML_00771 4.45e-150 - - - GM - - - NmrA-like family
CMLPILML_00772 3.3e-137 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
CMLPILML_00773 1.01e-222 iunH 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 inosine-uridine preferring nucleoside hydrolase
CMLPILML_00774 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CMLPILML_00775 1.08e-305 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CMLPILML_00776 0.0 oatA - - I - - - Acyltransferase
CMLPILML_00777 3.39e-226 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CMLPILML_00778 5.02e-185 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
CMLPILML_00779 1.1e-62 - - - S - - - Lipopolysaccharide assembly protein A domain
CMLPILML_00780 5.51e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
CMLPILML_00781 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
CMLPILML_00782 1.57e-37 - - - S - - - Protein of unknown function (DUF2929)
CMLPILML_00783 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
CMLPILML_00785 1.19e-231 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
CMLPILML_00786 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
CMLPILML_00787 1.65e-211 yitL - - S ko:K00243 - ko00000 S1 domain
CMLPILML_00788 1.17e-218 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
CMLPILML_00789 5.61e-82 ribT - - K ko:K02859 - ko00000 acetyltransferase
CMLPILML_00790 5.22e-174 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CMLPILML_00791 3.57e-136 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CMLPILML_00792 8.87e-168 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
CMLPILML_00793 1.39e-94 - - - M - - - Lysin motif
CMLPILML_00794 7.54e-126 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CMLPILML_00795 1.03e-151 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
CMLPILML_00796 5.27e-280 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
CMLPILML_00797 1.6e-306 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
CMLPILML_00798 7.91e-55 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CMLPILML_00799 1.27e-296 XK27_05225 - - S - - - Tetratricopeptide repeat protein
CMLPILML_00800 1.2e-182 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
CMLPILML_00801 1.55e-174 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CMLPILML_00802 0.0 - - - E - - - amino acid
CMLPILML_00803 1.28e-54 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
CMLPILML_00804 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CMLPILML_00805 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CMLPILML_00806 3.03e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CMLPILML_00807 1.69e-278 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CMLPILML_00808 5.46e-161 - - - S - - - (CBS) domain
CMLPILML_00809 2.31e-231 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
CMLPILML_00810 2.68e-134 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CMLPILML_00811 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CMLPILML_00812 8.68e-47 yabO - - J - - - S4 domain protein
CMLPILML_00813 5.29e-78 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
CMLPILML_00814 3.27e-80 - - - J ko:K07571 - ko00000 S1 RNA binding domain
CMLPILML_00815 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CMLPILML_00816 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CMLPILML_00817 0.0 - - - S - - - membrane
CMLPILML_00818 1.66e-207 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CMLPILML_00819 1.36e-245 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CMLPILML_00820 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
CMLPILML_00823 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
CMLPILML_00824 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CMLPILML_00825 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CMLPILML_00826 1.28e-154 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
CMLPILML_00827 3.6e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CMLPILML_00828 1.14e-105 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CMLPILML_00829 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CMLPILML_00830 6.34e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
CMLPILML_00831 5.06e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CMLPILML_00832 3.16e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
CMLPILML_00833 7.29e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CMLPILML_00834 4.88e-199 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CMLPILML_00835 6.08e-63 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CMLPILML_00836 9.07e-73 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CMLPILML_00837 7.46e-157 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CMLPILML_00838 4.26e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CMLPILML_00839 2.92e-34 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
CMLPILML_00840 7.74e-56 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CMLPILML_00841 6.02e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CMLPILML_00842 1.67e-46 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CMLPILML_00843 4.3e-124 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CMLPILML_00844 1.73e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CMLPILML_00845 1.32e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CMLPILML_00846 6.14e-122 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CMLPILML_00847 1.09e-74 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CMLPILML_00848 9.33e-107 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CMLPILML_00849 3.44e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
CMLPILML_00850 8.21e-92 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
CMLPILML_00851 2.42e-299 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CMLPILML_00852 4.87e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CMLPILML_00853 4.46e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CMLPILML_00854 1.89e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
CMLPILML_00855 1.92e-73 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CMLPILML_00856 4.46e-81 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CMLPILML_00857 2.19e-219 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CMLPILML_00858 3.85e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
CMLPILML_00859 1.1e-200 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CMLPILML_00860 1.86e-208 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CMLPILML_00861 2.19e-180 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CMLPILML_00862 8.78e-195 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CMLPILML_00863 7.82e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CMLPILML_00864 7.96e-85 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
CMLPILML_00865 1.8e-104 - - - - - - - -
CMLPILML_00866 5.1e-206 - - - GM - - - NmrA-like family
CMLPILML_00867 1.27e-141 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
CMLPILML_00868 1.83e-165 - - - G - - - Belongs to the phosphoglycerate mutase family
CMLPILML_00869 5.56e-70 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
CMLPILML_00870 5.88e-199 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
CMLPILML_00871 2.66e-56 - - - - - - - -
CMLPILML_00872 1.33e-35 - - - - - - - -
CMLPILML_00873 5.21e-164 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CMLPILML_00874 1.2e-236 - - - S - - - AAA domain
CMLPILML_00875 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
CMLPILML_00876 7.41e-131 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
CMLPILML_00877 5.16e-221 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CMLPILML_00878 1.17e-66 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CMLPILML_00879 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CMLPILML_00880 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
CMLPILML_00881 2.73e-102 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CMLPILML_00882 1.62e-179 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CMLPILML_00883 4.51e-199 lacT - - K ko:K02531 - ko00000,ko03000 PRD domain
CMLPILML_00884 5.42e-75 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
CMLPILML_00885 0.0 lacE 2.7.1.207 - G ko:K02787,ko:K02788 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system, EIIC
CMLPILML_00886 0.0 lacG 3.2.1.21, 3.2.1.85 - G ko:K01220,ko:K05350 ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
CMLPILML_00887 3.38e-128 - - - K ko:K03091 - ko00000,ko03021 sigma factor activity
CMLPILML_00888 1.19e-45 - - - - - - - -
CMLPILML_00889 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
CMLPILML_00890 6.78e-270 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
CMLPILML_00891 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CMLPILML_00892 8.29e-292 - - - G - - - Major Facilitator Superfamily
CMLPILML_00893 6.02e-246 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
CMLPILML_00894 1.48e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
CMLPILML_00895 9.78e-18 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
CMLPILML_00896 2.58e-131 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
CMLPILML_00897 2.69e-90 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CMLPILML_00898 6.1e-160 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CMLPILML_00899 5.35e-140 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
CMLPILML_00900 5.25e-149 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter
CMLPILML_00901 5.9e-188 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
CMLPILML_00902 2.35e-126 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CMLPILML_00903 3.25e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CMLPILML_00904 1.02e-198 - - - P ko:K10716 - ko00000,ko02000 Ion transport protein
CMLPILML_00905 3.25e-44 - - - - - - - -
CMLPILML_00906 3.19e-145 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
CMLPILML_00907 6.96e-33 - - - - - - - -
CMLPILML_00908 2.52e-106 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CMLPILML_00909 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CMLPILML_00910 9.41e-69 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CMLPILML_00911 1.53e-140 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CMLPILML_00912 3.68e-45 - - - S - - - Protein of unknown function (DUF2508)
CMLPILML_00913 7.09e-147 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CMLPILML_00914 8.23e-70 yaaQ - - S - - - Cyclic-di-AMP receptor
CMLPILML_00915 1.39e-197 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
CMLPILML_00916 3.89e-77 yabA - - L - - - Involved in initiation control of chromosome replication
CMLPILML_00917 8.76e-201 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CMLPILML_00918 2.57e-168 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
CMLPILML_00919 8.12e-113 - - - S - - - ECF transporter, substrate-specific component
CMLPILML_00920 3.02e-170 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
CMLPILML_00921 3.43e-127 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
CMLPILML_00922 8.61e-251 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CMLPILML_00923 6.62e-11 - - - D - - - nuclear chromosome segregation
CMLPILML_00924 2.34e-11 - - - D - - - nuclear chromosome segregation
CMLPILML_00925 6.8e-219 - - - - - - - -
CMLPILML_00926 1.29e-80 - - - - - - - -
CMLPILML_00927 3.27e-306 eriC - - P ko:K03281 - ko00000 chloride
CMLPILML_00928 1.49e-64 - - - - - - - -
CMLPILML_00929 1.2e-128 - - - S - - - Protein of unknown function (DUF3990)
CMLPILML_00930 8.5e-242 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CMLPILML_00931 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CMLPILML_00932 3.38e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CMLPILML_00933 1.53e-102 apfA 3.6.1.61 - F ko:K18445 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
CMLPILML_00934 2.75e-64 - - - L ko:K07473 - ko00000,ko02048 bacterial-type proximal promoter sequence-specific DNA binding
CMLPILML_00935 1.01e-71 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
CMLPILML_00936 3.25e-298 bbsF_1 2.8.3.19 - C ko:K18702 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
CMLPILML_00937 2.19e-196 - - - K - - - helix_turn_helix, arabinose operon control protein
CMLPILML_00938 0.0 bglC1 3.2.1.21, 3.2.1.52 GH3 G ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501 ko00000,ko00001,ko00002,ko01000 hydrolase, family 3
CMLPILML_00939 0.0 scrA5 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CMLPILML_00940 0.0 - 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolases family 32
CMLPILML_00941 6.18e-199 - - - K - - - Helix-turn-helix XRE-family like proteins
CMLPILML_00942 1.51e-100 - - - - - - - -
CMLPILML_00943 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
CMLPILML_00944 1.45e-150 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CMLPILML_00945 1.55e-133 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
CMLPILML_00946 1.05e-102 - - - K - - - LytTr DNA-binding domain
CMLPILML_00947 2.75e-167 - - - S - - - membrane
CMLPILML_00948 3.69e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CMLPILML_00949 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CMLPILML_00950 5.96e-09 - - - M - - - LPXTG-motif cell wall anchor domain protein
CMLPILML_00951 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
CMLPILML_00952 0.0 nisT - - V ko:K06147,ko:K20485 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 ABC transporter
CMLPILML_00953 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CMLPILML_00954 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CMLPILML_00955 1.26e-131 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CMLPILML_00956 1.16e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CMLPILML_00957 1.08e-67 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
CMLPILML_00958 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CMLPILML_00959 1.79e-267 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CMLPILML_00960 2.44e-234 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
CMLPILML_00961 3.84e-299 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CMLPILML_00962 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CMLPILML_00963 1.08e-56 yrzL - - S - - - Belongs to the UPF0297 family
CMLPILML_00964 1.01e-95 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CMLPILML_00965 1.27e-66 yrzB - - S - - - Belongs to the UPF0473 family
CMLPILML_00966 1.33e-118 cvpA - - S - - - Colicin V production protein
CMLPILML_00967 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CMLPILML_00968 8.93e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
CMLPILML_00969 2.57e-90 yslB - - S - - - Protein of unknown function (DUF2507)
CMLPILML_00970 1.14e-186 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
CMLPILML_00971 4.91e-150 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CMLPILML_00972 1.06e-280 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CMLPILML_00973 1.51e-203 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
CMLPILML_00974 2.54e-33 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CMLPILML_00975 1.47e-67 - - - - - - - -
CMLPILML_00976 1.54e-270 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
CMLPILML_00977 2.52e-229 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
CMLPILML_00978 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
CMLPILML_00979 0.0 pbp1B 2.4.1.129 GT51 M ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin binding protein transpeptidase domain
CMLPILML_00980 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
CMLPILML_00981 0.0 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
CMLPILML_00982 3.99e-74 - - - - - - - -
CMLPILML_00983 0.0 sasH 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
CMLPILML_00984 1.44e-127 yutD - - S - - - Protein of unknown function (DUF1027)
CMLPILML_00985 4.87e-190 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CMLPILML_00986 1.62e-135 - - - S - - - Protein of unknown function (DUF1461)
CMLPILML_00987 1.45e-151 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
CMLPILML_00988 2.17e-230 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
CMLPILML_00989 2.37e-79 yugI - - J ko:K07570 - ko00000 general stress protein
CMLPILML_00990 3e-82 - - - M - - - Glycosyltransferase like family 2
CMLPILML_00991 5.7e-160 - - - S - - - Alpha/beta hydrolase family
CMLPILML_00992 9.68e-83 - - - - - - - -
CMLPILML_00993 7.71e-231 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CMLPILML_00994 8.76e-283 - - - S - - - CAAX protease self-immunity
CMLPILML_00995 4.1e-307 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
CMLPILML_00996 4.09e-126 - - - K - - - Bacterial regulatory proteins, tetR family
CMLPILML_00997 8.47e-180 - - - - - - - -
CMLPILML_00998 0.0 - - - S - - - Cysteine-rich secretory protein family
CMLPILML_00999 6.59e-265 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
CMLPILML_01000 1.03e-151 - - - - - - - -
CMLPILML_01001 0.0 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
CMLPILML_01002 1.02e-239 yibE - - S - - - overlaps another CDS with the same product name
CMLPILML_01003 1.61e-155 yibF - - S - - - overlaps another CDS with the same product name
CMLPILML_01004 6.44e-201 - - - I - - - alpha/beta hydrolase fold
CMLPILML_01005 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
CMLPILML_01006 2.04e-167 - - - K ko:K03710 - ko00000,ko03000 UTRA
CMLPILML_01007 5.87e-276 agaS - - G ko:K02082 - ko00000,ko01000 SIS domain
CMLPILML_01008 2.64e-291 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
CMLPILML_01009 5.59e-109 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
CMLPILML_01010 1.87e-196 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
CMLPILML_01011 2.13e-190 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
CMLPILML_01012 1.6e-89 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
CMLPILML_01013 3.49e-23 - - - S - - - PD-(D/E)XK nuclease family transposase
CMLPILML_01014 8.35e-277 - - - S - - - zinc-ribbon domain
CMLPILML_01015 4.51e-17 - - - - - - - -
CMLPILML_01016 5.62e-216 - - - - - - - -
CMLPILML_01017 3.82e-114 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
CMLPILML_01018 1.89e-129 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CMLPILML_01019 4.26e-171 - - - K - - - UTRA domain
CMLPILML_01020 3.05e-192 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
CMLPILML_01021 4.96e-113 usp5 - - T - - - universal stress protein
CMLPILML_01023 9.6e-217 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
CMLPILML_01024 2.58e-181 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CMLPILML_01025 2.46e-169 phnB - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
CMLPILML_01026 8.69e-189 - - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
CMLPILML_01027 6.97e-107 - - - - - - - -
CMLPILML_01028 0.0 - - - S - - - Calcineurin-like phosphoesterase
CMLPILML_01029 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
CMLPILML_01030 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
CMLPILML_01031 2.3e-83 - - - - - - - -
CMLPILML_01032 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
CMLPILML_01033 8.75e-177 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CMLPILML_01034 1.83e-134 yitW - - S - - - Iron-sulfur cluster assembly protein
CMLPILML_01035 4.42e-292 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
CMLPILML_01036 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
CMLPILML_01037 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
CMLPILML_01038 2.19e-290 yqjV - - EGP - - - Major Facilitator Superfamily
CMLPILML_01039 9.39e-238 lacD 4.1.2.40 - G ko:K01635 ko00052,ko01100,ko02024,map00052,map01100,map02024 ko00000,ko00001,ko01000 Belongs to the aldolase LacD family
CMLPILML_01040 0.0 - - - D - - - transport
CMLPILML_01041 9.83e-175 rpl - - K - - - Helix-turn-helix domain, rpiR family
CMLPILML_01042 6.42e-210 fruK-1 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
CMLPILML_01043 0.0 fruC 2.7.1.202 - GT ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CMLPILML_01044 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
CMLPILML_01045 0.0 - - - S - - - Bacterial membrane protein, YfhO
CMLPILML_01046 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
CMLPILML_01047 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
CMLPILML_01048 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
CMLPILML_01049 1.06e-95 - - - - - - - -
CMLPILML_01050 1.47e-162 - - - - - - - -
CMLPILML_01051 1.75e-39 - - - - - - - -
CMLPILML_01052 3.38e-46 - - - S - - - Protein of unknown function (DUF2922)
CMLPILML_01053 0.0 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CMLPILML_01054 0.0 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
CMLPILML_01055 2.55e-185 - 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
CMLPILML_01056 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
CMLPILML_01057 6.12e-230 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
CMLPILML_01058 2.11e-175 - - - - - - - -
CMLPILML_01059 3.41e-193 - - - - - - - -
CMLPILML_01060 2.22e-97 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
CMLPILML_01061 1.11e-171 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CMLPILML_01062 4.38e-56 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CMLPILML_01063 5.36e-92 - - - S - - - GtrA-like protein
CMLPILML_01064 1.56e-227 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
CMLPILML_01065 7.1e-152 - - - - - - - -
CMLPILML_01066 2.21e-195 - - - U ko:K05340 - ko00000,ko02000 sugar transport
CMLPILML_01067 4.25e-219 - - - G - - - Aldose 1-epimerase
CMLPILML_01068 3.28e-260 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
CMLPILML_01069 1.13e-145 plsY1 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CMLPILML_01070 0.0 XK27_08315 - - M - - - Sulfatase
CMLPILML_01071 9.21e-309 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CMLPILML_01073 0.0 pepC1 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
CMLPILML_01074 2.24e-160 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
CMLPILML_01075 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
CMLPILML_01076 8.46e-81 - - - - - - - -
CMLPILML_01077 4.87e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CMLPILML_01078 1.47e-100 - - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
CMLPILML_01079 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
CMLPILML_01080 2.08e-105 - - - - - - - -
CMLPILML_01081 1.29e-315 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMLPILML_01082 3.99e-166 gntR - - K ko:K03489 - ko00000,ko03000 UTRA
CMLPILML_01083 2.83e-57 - - - S - - - Domain of unknown function (DUF3284)
CMLPILML_01084 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
CMLPILML_01085 1.1e-172 - - - K ko:K03492 - ko00000,ko03000 UTRA
CMLPILML_01086 1.76e-68 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
CMLPILML_01087 2.42e-70 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
CMLPILML_01088 0.0 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMLPILML_01089 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
CMLPILML_01090 3.8e-202 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
CMLPILML_01091 2.21e-148 - - - - - - - -
CMLPILML_01093 2.85e-147 - - - E - - - Belongs to the SOS response-associated peptidase family
CMLPILML_01094 4.06e-247 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
CMLPILML_01095 6.82e-119 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 MafB19-like deaminase
CMLPILML_01096 1.52e-129 - - - S ko:K06872 - ko00000 TPM domain
CMLPILML_01097 1.44e-114 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
CMLPILML_01098 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CMLPILML_01099 2.07e-189 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
CMLPILML_01100 1.6e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CMLPILML_01101 3.56e-206 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CMLPILML_01102 2.99e-49 veg - - S - - - Biofilm formation stimulator VEG
CMLPILML_01103 7.77e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
CMLPILML_01104 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CMLPILML_01105 9.21e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CMLPILML_01106 1.05e-227 yvdE - - K - - - helix_turn _helix lactose operon repressor
CMLPILML_01107 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
CMLPILML_01108 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
CMLPILML_01109 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
CMLPILML_01110 6.6e-150 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
CMLPILML_01111 5.55e-268 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CMLPILML_01112 1.58e-293 malE - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
CMLPILML_01113 0.0 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
CMLPILML_01114 2.93e-199 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
CMLPILML_01115 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
CMLPILML_01116 0.0 - - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
CMLPILML_01117 4.73e-96 - - - S - - - Domain of unknown function (DUF1934)
CMLPILML_01118 3.78e-92 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CMLPILML_01119 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CMLPILML_01120 6.24e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CMLPILML_01121 4.58e-305 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
CMLPILML_01122 1.66e-136 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CMLPILML_01123 1.59e-172 - - - K - - - DNA-binding helix-turn-helix protein
CMLPILML_01124 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
CMLPILML_01126 5.2e-229 - - - K - - - Helix-turn-helix
CMLPILML_01127 7.98e-50 - - - - - - - -
CMLPILML_01128 9.94e-90 doc - - S ko:K07341 - ko00000,ko02048 Fic/DOC family
CMLPILML_01129 1.63e-121 - - - K - - - Bacterial regulatory proteins, tetR family
CMLPILML_01130 6.29e-146 - - - S - - - Flavodoxin-like fold
CMLPILML_01131 7.78e-63 yjdF3 - - S - - - Protein of unknown function (DUF2992)
CMLPILML_01133 9.45e-67 - - - - - - - -
CMLPILML_01134 5.66e-67 - - - S - - - Domain of unknown function (DUF4160)
CMLPILML_01135 3.72e-86 yjdF3 - - S - - - Protein of unknown function (DUF2992)
CMLPILML_01136 2.08e-127 ogt 2.1.1.63 - L ko:K00567 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CMLPILML_01137 1.97e-123 - - - - - - - -
CMLPILML_01138 0.0 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
CMLPILML_01139 0.0 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
CMLPILML_01140 9.92e-266 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
CMLPILML_01141 1.64e-52 - - - - - - - -
CMLPILML_01142 4.86e-28 - 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CMLPILML_01143 3.68e-238 - 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CMLPILML_01144 1.67e-101 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
CMLPILML_01145 4.92e-104 - - - - - - - -
CMLPILML_01147 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
CMLPILML_01148 2.21e-294 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CMLPILML_01149 0.0 rafA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
CMLPILML_01150 3.24e-51 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction
CMLPILML_01151 3.88e-50 - 3.1.21.3 - L ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
CMLPILML_01152 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
CMLPILML_01153 4.26e-32 - - - K - - - Cro/C1-type HTH DNA-binding domain
CMLPILML_01154 3.22e-137 - - - F - - - helicase superfamily c-terminal domain
CMLPILML_01157 6.8e-32 - - - - - - - -
CMLPILML_01158 3.92e-38 - - - - - - - -
CMLPILML_01159 2.69e-256 - - - L - - - Protein of unknown function (DUF2800)
CMLPILML_01160 1.44e-123 - - - S - - - Protein of unknown function (DUF2815)
CMLPILML_01161 0.0 - 2.7.7.7 - L ko:K02334 - ko00000,ko01000 DNA polymerase
CMLPILML_01162 2.81e-88 - - - S - - - Psort location Cytoplasmic, score
CMLPILML_01163 0.0 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4
CMLPILML_01164 1.06e-62 - - - S - - - VRR_NUC
CMLPILML_01165 0.0 - - - L - - - SNF2 family N-terminal domain
CMLPILML_01166 3.56e-113 - - - - - - - -
CMLPILML_01167 2.4e-130 - - - - - - - -
CMLPILML_01168 8.18e-309 - - - KL - - - DNA methylase
CMLPILML_01169 3.2e-150 - - - S - - - Psort location Cytoplasmic, score
CMLPILML_01170 2.05e-42 - - - S - - - Domain of unknown function (DUF5049)
CMLPILML_01171 0.0 - - - S - - - overlaps another CDS with the same product name
CMLPILML_01172 4.58e-308 - - - S - - - Phage portal protein
CMLPILML_01173 4.66e-156 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
CMLPILML_01174 1.58e-282 - - - S - - - Phage capsid family
CMLPILML_01175 3.08e-57 - - - S - - - Phage gp6-like head-tail connector protein
CMLPILML_01176 1.29e-88 - - - S - - - Phage head-tail joining protein
CMLPILML_01177 5.95e-92 - - - S - - - Bacteriophage holin family
CMLPILML_01178 3.19e-186 - - - M - - - Glycosyl hydrolases family 25
CMLPILML_01179 3.04e-48 - - - - - - - -
CMLPILML_01180 0.0 - - - L - - - Recombinase zinc beta ribbon domain
CMLPILML_01181 0.0 - - - L - - - Recombinase
CMLPILML_01182 8.23e-23 - 2.1.1.303 - K ko:K04096,ko:K20421 ko01059,ko01130,map01059,map01130 ko00000,ko00001,ko00002,ko01000 DNA-binding transcription factor activity
CMLPILML_01183 1.21e-35 - - - M - - - domain protein
CMLPILML_01184 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CMLPILML_01185 6.34e-156 - - - S ko:K01992,ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
CMLPILML_01186 3.41e-168 spaF - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
CMLPILML_01187 2.12e-309 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
CMLPILML_01188 1.36e-209 XK27_10120 - - K - - - S-adenosyl-l-methionine hydroxide adenosyltransferase
CMLPILML_01189 1.8e-123 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
CMLPILML_01190 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
CMLPILML_01191 5.56e-183 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
CMLPILML_01192 3.27e-153 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
CMLPILML_01193 0.0 rtpR 1.17.4.2 - F ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 ribonucleoside-triphosphate reductase activity
CMLPILML_01194 3.15e-85 - - - S - - - Domain of unknown function (DUF4430)
CMLPILML_01195 1.19e-113 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF transporter, substrate-specific component
CMLPILML_01196 5.03e-122 - - - S - - - Cob(I)alamin adenosyltransferase
CMLPILML_01197 1.86e-165 - - - L - - - Helix-turn-helix domain
CMLPILML_01198 7.5e-29 - - - L ko:K07497 - ko00000 hmm pf00665
CMLPILML_01199 1.61e-49 - - - L ko:K07497 - ko00000 hmm pf00665
CMLPILML_01200 1.51e-194 - - - S - - - hydrolase
CMLPILML_01202 1.86e-215 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
CMLPILML_01203 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CMLPILML_01204 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CMLPILML_01205 1.29e-64 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CMLPILML_01206 4.64e-265 camS - - S - - - sex pheromone
CMLPILML_01207 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CMLPILML_01208 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
CMLPILML_01209 3.07e-149 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
CMLPILML_01210 4.37e-131 - - - S - - - ECF transporter, substrate-specific component
CMLPILML_01212 8.17e-112 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
CMLPILML_01213 7.2e-174 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
CMLPILML_01214 0.0 epsU - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
CMLPILML_01215 1.79e-292 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
CMLPILML_01216 1.29e-189 - - - - - - - -
CMLPILML_01217 0.0 - - - V - - - ABC transporter transmembrane region
CMLPILML_01218 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
CMLPILML_01219 6.16e-197 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CMLPILML_01220 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CMLPILML_01221 1.68e-67 - - - M - - - Glycosyltransferase like family 2
CMLPILML_01222 0.0 - - - M - - - Glycosyltransferase like family 2
CMLPILML_01223 7.18e-259 - - - M - - - Glycosyl transferases group 1
CMLPILML_01224 1.75e-182 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
CMLPILML_01225 2.31e-87 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
CMLPILML_01226 6.31e-159 gntR1 - - K ko:K03710 - ko00000,ko03000 UTRA
CMLPILML_01227 2.15e-246 - - - - - - - -
CMLPILML_01228 1.44e-69 XK27_05625 - - P - - - Rhodanese Homology Domain
CMLPILML_01231 1.53e-214 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 lactate/malate dehydrogenase, alpha/beta C-terminal domain
CMLPILML_01232 1.43e-187 - - - K - - - SIS domain
CMLPILML_01234 3.9e-243 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
CMLPILML_01235 7.78e-80 - - - S - - - Bacterial protein of unknown function (DUF898)
CMLPILML_01237 2.22e-159 - - - M - - - LysM domain protein
CMLPILML_01238 4.59e-175 - - - M - - - LysM domain protein
CMLPILML_01239 1.83e-175 - - - S - - - Putative ABC-transporter type IV
CMLPILML_01240 1.45e-232 - - - M - - - Glycosyl hydrolases family 25
CMLPILML_01241 1.73e-87 - - - S - - - Pfam:Phage_holin_6_1
CMLPILML_01242 5.31e-58 - - - - - - - -
CMLPILML_01243 1e-84 - - - - - - - -
CMLPILML_01245 3.59e-113 - - - - - - - -
CMLPILML_01246 0.0 - - - - - - - -
CMLPILML_01247 3.5e-126 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2313)
CMLPILML_01248 8.59e-271 - - - S - - - Baseplate J-like protein
CMLPILML_01249 9.94e-79 - - - S - - - Protein of unknown function (DUF2634)
CMLPILML_01250 6.7e-72 - - - S - - - Protein of unknown function (DUF2577)
CMLPILML_01251 2.21e-253 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
CMLPILML_01252 8.91e-154 xkdP - - S - - - protein containing LysM domain
CMLPILML_01253 0.0 - - - S - - - phage tail tape measure protein
CMLPILML_01254 1.57e-88 xkdN - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
CMLPILML_01255 3.04e-110 - - - S - - - Phage tail tube protein
CMLPILML_01256 1.67e-307 - - - S - - - Phage tail sheath C-terminal domain
CMLPILML_01257 8.81e-39 - - - - - - - -
CMLPILML_01258 4.75e-91 - - - - - - - -
CMLPILML_01259 5.61e-98 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
CMLPILML_01260 1.55e-79 - - - - - - - -
CMLPILML_01261 7.13e-87 - - - - - - - -
CMLPILML_01262 2.94e-242 - - - - - - - -
CMLPILML_01263 1.48e-117 - - - S - - - viral scaffold
CMLPILML_01264 6.92e-282 - - - S - - - Phage Mu protein F like protein
CMLPILML_01265 0.0 - - - S - - - Phage portal protein, SPP1 Gp6-like
CMLPILML_01266 1.01e-314 - - - S - - - DNA packaging
CMLPILML_01267 3.95e-115 - - - S - - - Terminase small subunit
CMLPILML_01268 2.06e-152 - - - - - - - -
CMLPILML_01270 4.56e-154 - - - C - - - Domain of unknown function (DUF4145)
CMLPILML_01271 4.13e-65 - - - K - - - chromosome segregation
CMLPILML_01273 1.83e-123 - - - - - - - -
CMLPILML_01274 3.18e-16 - - - - - - - -
CMLPILML_01275 2.62e-40 - - - - - - - -
CMLPILML_01276 1.97e-48 - - - - - - - -
CMLPILML_01277 2.42e-30 - - - - - - - -
CMLPILML_01278 4.17e-102 - - - L - - - Endodeoxyribonuclease RusA
CMLPILML_01283 5.21e-41 - - - - - - - -
CMLPILML_01285 8.57e-163 - - - K ko:K07741 - ko00000 AntA/AntB antirepressor
CMLPILML_01287 1.79e-26 - - - S - - - sequence-specific DNA binding
CMLPILML_01288 3.23e-51 - - - L - - - Helix-turn-helix domain
CMLPILML_01289 1.78e-170 - - - S - - - Protein of unknown function (DUF1071)
CMLPILML_01291 1.15e-73 - - - - - - - -
CMLPILML_01292 1.73e-22 - - - - - - - -
CMLPILML_01297 1.39e-70 - - - S - - - Domain of unknown function (DUF771)
CMLPILML_01298 3.93e-07 - - - K - - - Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CMLPILML_01299 1.98e-72 - - - K - - - Helix-turn-helix domain
CMLPILML_01300 5.98e-105 - - - S - - - Pfam:Peptidase_M78
CMLPILML_01301 4.6e-128 - - - S - - - Domain of Unknown Function with PDB structure (DUF3862)
CMLPILML_01303 7.41e-156 - - - S - - - Phage integrase family
CMLPILML_01304 7.85e-80 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
CMLPILML_01305 1.7e-122 - - - K - - - acetyltransferase
CMLPILML_01306 7.35e-198 - - - S - - - PD-(D/E)XK nuclease family transposase
CMLPILML_01308 1.53e-210 yvgN - - C - - - Aldo keto reductase
CMLPILML_01309 1.45e-313 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
CMLPILML_01310 5.96e-173 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
CMLPILML_01311 6.31e-223 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CMLPILML_01312 2.67e-239 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
CMLPILML_01313 6.19e-202 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CMLPILML_01314 6.07e-225 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CMLPILML_01315 2.64e-49 - - - - - - - -
CMLPILML_01316 8.75e-236 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CMLPILML_01317 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CMLPILML_01318 2.35e-125 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CMLPILML_01319 1.29e-162 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
CMLPILML_01320 2.75e-308 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
CMLPILML_01321 1.39e-156 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
CMLPILML_01322 2.33e-262 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
CMLPILML_01323 1.38e-312 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
CMLPILML_01324 1.73e-249 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CMLPILML_01325 7.62e-126 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CMLPILML_01326 1.85e-172 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
CMLPILML_01327 3.01e-166 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
CMLPILML_01328 2.58e-296 ymfH - - S - - - Peptidase M16
CMLPILML_01329 3.51e-292 ymfF - - S - - - Peptidase M16 inactive domain protein
CMLPILML_01330 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
CMLPILML_01331 8.29e-100 - - - S - - - Protein of unknown function (DUF1149)
CMLPILML_01332 1.88e-135 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CMLPILML_01333 4.6e-271 XK27_05220 - - S - - - AI-2E family transporter
CMLPILML_01334 1.88e-88 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
CMLPILML_01335 6.1e-256 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
CMLPILML_01336 5.46e-300 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
CMLPILML_01337 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
CMLPILML_01338 2.38e-221 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
CMLPILML_01339 2.24e-194 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CMLPILML_01340 1.7e-146 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
CMLPILML_01341 8.77e-144 - - - S - - - CYTH
CMLPILML_01342 2.2e-139 yjbH - - Q - - - Thioredoxin
CMLPILML_01343 4.94e-209 coiA - - S ko:K06198 - ko00000 Competence protein
CMLPILML_01344 2.82e-154 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
CMLPILML_01345 1e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CMLPILML_01346 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CMLPILML_01347 7.45e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
CMLPILML_01348 4.33e-36 - - - - - - - -
CMLPILML_01349 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
CMLPILML_01350 2.17e-59 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
CMLPILML_01351 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CMLPILML_01352 4.69e-202 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
CMLPILML_01353 8.42e-102 - - - - - - - -
CMLPILML_01354 4.08e-117 - - - - - - - -
CMLPILML_01355 6.36e-147 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
CMLPILML_01356 1.1e-187 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
CMLPILML_01357 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CMLPILML_01358 2.41e-279 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
CMLPILML_01359 5.82e-283 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
CMLPILML_01360 4.31e-278 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
CMLPILML_01361 5.22e-228 ybcH - - D ko:K06889 - ko00000 Alpha beta
CMLPILML_01363 6.93e-195 supH - - S - - - haloacid dehalogenase-like hydrolase
CMLPILML_01364 1.34e-261 - - - EGP - - - Major Facilitator Superfamily
CMLPILML_01365 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
CMLPILML_01366 3.2e-214 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CMLPILML_01367 1.18e-26 - - - S - - - Protein of unknown function (DUF3042)
CMLPILML_01368 1.47e-76 yqhL - - P - - - Rhodanese-like protein
CMLPILML_01369 1.15e-47 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
CMLPILML_01370 9.32e-154 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
CMLPILML_01371 1.17e-119 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CMLPILML_01372 3.09e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
CMLPILML_01373 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
CMLPILML_01374 0.0 - - - S - - - membrane
CMLPILML_01375 3.09e-96 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CMLPILML_01376 1.11e-261 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CMLPILML_01377 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CMLPILML_01378 9.43e-260 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CMLPILML_01379 1.01e-83 yodB - - K - - - Transcriptional regulator, HxlR family
CMLPILML_01380 6.34e-178 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CMLPILML_01381 8.53e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
CMLPILML_01382 2.72e-216 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CMLPILML_01383 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CMLPILML_01384 3.11e-169 csrR - - K - - - response regulator
CMLPILML_01385 7.11e-124 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
CMLPILML_01386 1.45e-279 ylbM - - S - - - Belongs to the UPF0348 family
CMLPILML_01387 1.78e-77 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CMLPILML_01388 2.26e-142 yqeK - - H - - - Hydrolase, HD family
CMLPILML_01389 1.16e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CMLPILML_01390 1.94e-269 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
CMLPILML_01391 1.25e-119 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
CMLPILML_01392 2.75e-244 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CMLPILML_01393 3.54e-75 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CMLPILML_01394 9.64e-38 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
CMLPILML_01395 1.29e-112 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CMLPILML_01396 8.85e-170 - - - S ko:K01992 - ko00000,ko00002,ko02000 domain protein
CMLPILML_01397 5.34e-218 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
CMLPILML_01398 1.82e-97 - - - S - - - Protein of unknown function (DUF3021)
CMLPILML_01399 6.56e-95 - - - K - - - LytTr DNA-binding domain
CMLPILML_01400 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CMLPILML_01401 4.54e-210 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
CMLPILML_01402 0.0 dnaB2 - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
CMLPILML_01403 5.92e-107 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CMLPILML_01404 6.46e-137 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CMLPILML_01405 2.85e-206 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CMLPILML_01406 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CMLPILML_01407 6.03e-292 dpaL 4.3.1.15 - E ko:K01751 - ko00000,ko01000 Pyridoxal-phosphate dependent enzyme
CMLPILML_01408 4.61e-284 - - - EGP - - - Major Facilitator
CMLPILML_01409 6.53e-90 - - - K - - - Transcriptional regulator
CMLPILML_01410 1.92e-17 - - - - - - - -
CMLPILML_01411 5.98e-100 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
CMLPILML_01412 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
CMLPILML_01413 7.5e-153 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
CMLPILML_01414 1.23e-249 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMLPILML_01415 8.76e-121 - - - S - - - Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)
CMLPILML_01416 2.92e-231 asnA2 3.5.1.1 - E ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
CMLPILML_01417 0.0 - - - E - - - Peptidase family M20/M25/M40
CMLPILML_01418 8.28e-169 - - - K ko:K03710 - ko00000,ko03000 UTRA
CMLPILML_01419 6.18e-157 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CMLPILML_01420 4.28e-71 ytpP - - CO - - - Thioredoxin
CMLPILML_01421 3.11e-19 - - - S - - - PD-(D/E)XK nuclease family transposase
CMLPILML_01422 1.34e-53 - - - S - - - PD-(D/E)XK nuclease family transposase
CMLPILML_01423 3.87e-161 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CMLPILML_01424 3.63e-289 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
CMLPILML_01425 3.26e-173 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CMLPILML_01426 1.01e-100 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
CMLPILML_01427 4.48e-90 - - - - - - - -
CMLPILML_01428 2.42e-72 - - - S - - - YtxH-like protein
CMLPILML_01429 5.88e-201 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
CMLPILML_01430 1.3e-238 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
CMLPILML_01431 0.0 yhaN - - L - - - AAA domain
CMLPILML_01432 5.64e-295 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
CMLPILML_01433 3.16e-73 yheA - - S - - - Belongs to the UPF0342 family
CMLPILML_01434 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
CMLPILML_01435 1.07e-207 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
CMLPILML_01437 0.0 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
CMLPILML_01438 1.43e-87 - - - - - - - -
CMLPILML_01439 1.11e-123 - - - L - - - NUDIX domain
CMLPILML_01440 2.08e-196 - 2.7.1.95 - F ko:K00897 - ko00000,ko01000,ko01504 Belongs to the aminoglycoside phosphotransferase family
CMLPILML_01441 2.11e-253 flp - - V - - - Beta-lactamase
CMLPILML_01443 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
CMLPILML_01444 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CMLPILML_01445 2.08e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CMLPILML_01446 1.04e-27 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
CMLPILML_01447 4.56e-266 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CMLPILML_01448 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CMLPILML_01449 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CMLPILML_01450 4.55e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
CMLPILML_01451 7.47e-112 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CMLPILML_01452 2.5e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CMLPILML_01453 1.12e-213 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
CMLPILML_01454 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
CMLPILML_01455 8.13e-99 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
CMLPILML_01456 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
CMLPILML_01457 2.56e-218 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
CMLPILML_01458 1.19e-280 - - - I - - - Protein of unknown function (DUF2974)
CMLPILML_01459 0.0 - - - - - - - -
CMLPILML_01460 2.64e-151 - - - S ko:K07507 - ko00000,ko02000 MgtC family
CMLPILML_01462 6.94e-146 - - - S - - - HAD hydrolase, family IA, variant
CMLPILML_01463 7.49e-29 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
CMLPILML_01464 4.18e-118 - - - S - - - Protein of unknown function (DUF3278)
CMLPILML_01465 1.39e-256 ydhF - - S - - - Aldo keto reductase
CMLPILML_01467 5.09e-285 - - - S - - - Sterol carrier protein domain
CMLPILML_01468 6.39e-150 - - - S ko:K07118 - ko00000 NAD(P)H-binding
CMLPILML_01469 2.7e-169 - - - S - - - Protein of unknown function (DUF975)
CMLPILML_01470 3.71e-177 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
CMLPILML_01471 4.34e-198 yitS - - S - - - EDD domain protein, DegV family
CMLPILML_01472 1.92e-26 - - - - - - - -
CMLPILML_01473 0.0 fusA1 - - J - - - elongation factor G
CMLPILML_01474 1.72e-214 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
CMLPILML_01475 3.18e-19 - - - S - - - CsbD-like
CMLPILML_01476 1.29e-54 - - - S - - - Transglycosylase associated protein
CMLPILML_01477 9.2e-207 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
CMLPILML_01478 0.0 - - - L - - - Helicase C-terminal domain protein
CMLPILML_01479 4.93e-212 - - - S - - - Alpha beta hydrolase
CMLPILML_01480 3.66e-54 - - - - - - - -
CMLPILML_01481 2.88e-229 ydbI - - K - - - AI-2E family transporter
CMLPILML_01482 0.0 - 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 pyridine nucleotide-disulfide oxidoreductase
CMLPILML_01483 2.28e-271 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CMLPILML_01484 1.8e-135 - - - E - - - GDSL-like Lipase/Acylhydrolase
CMLPILML_01485 1.71e-246 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CMLPILML_01486 0.0 - - - S - - - domain, Protein
CMLPILML_01487 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
CMLPILML_01488 0.0 - - - E ko:K03294 - ko00000 Amino Acid
CMLPILML_01489 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 AAA domain (Cdc48 subfamily)
CMLPILML_01490 1.76e-199 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
CMLPILML_01491 4.61e-308 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMLPILML_01492 7.34e-54 - - - - - - - -
CMLPILML_01493 1.52e-274 - - - E - - - Major Facilitator Superfamily
CMLPILML_01494 2.47e-223 pbpX2 - - V - - - Beta-lactamase
CMLPILML_01495 0.0 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CMLPILML_01496 3.63e-50 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CMLPILML_01497 9.88e-305 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
CMLPILML_01498 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CMLPILML_01499 9.7e-07 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
CMLPILML_01500 4.82e-60 - - - - - - - -
CMLPILML_01501 5.68e-260 - - - S - - - Membrane
CMLPILML_01502 7.91e-78 - - - - - - - -
CMLPILML_01503 8.97e-66 - - - - - - - -
CMLPILML_01504 9.94e-60 - - - - - - - -
CMLPILML_01506 2.47e-112 ykuL - - S - - - (CBS) domain
CMLPILML_01507 0.0 cadA - - P - - - P-type ATPase
CMLPILML_01508 1.39e-257 napA - - P - - - Sodium/hydrogen exchanger family
CMLPILML_01510 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
CMLPILML_01511 1.24e-204 mutR - - K - - - Helix-turn-helix XRE-family like proteins
CMLPILML_01512 3.3e-36 - - - - - - - -
CMLPILML_01513 8.28e-47 - - - - - - - -
CMLPILML_01514 1.03e-155 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CMLPILML_01515 1.75e-202 - - - S - - - Protein of unknown function (DUF979)
CMLPILML_01516 3.9e-147 - - - S - - - Protein of unknown function (DUF969)
CMLPILML_01517 1.66e-303 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
CMLPILML_01518 0.0 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
CMLPILML_01519 8.25e-63 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
CMLPILML_01520 8.24e-137 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
CMLPILML_01521 7.17e-258 - - - S - - - DUF218 domain
CMLPILML_01522 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CMLPILML_01523 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
CMLPILML_01524 1.05e-231 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
CMLPILML_01525 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
CMLPILML_01526 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CMLPILML_01527 6.33e-226 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
CMLPILML_01528 4.97e-313 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
CMLPILML_01529 2.01e-214 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, phosphonate, periplasmic substrate-binding protein
CMLPILML_01530 2.8e-256 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
CMLPILML_01531 8.85e-226 - 3.4.11.5 - I ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
CMLPILML_01532 9.29e-250 - - - V - - - Beta-lactamase
CMLPILML_01533 0.0 pts29C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMLPILML_01534 1.05e-203 gspK - - G - - - BadF/BadG/BcrA/BcrD ATPase family
CMLPILML_01535 1.04e-270 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
CMLPILML_01536 1.84e-196 - - - S - - - Putative esterase
CMLPILML_01537 1.13e-249 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
CMLPILML_01538 1.05e-171 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
CMLPILML_01539 9.42e-202 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CMLPILML_01540 9.68e-173 - - - S ko:K07090 - ko00000 membrane transporter protein
CMLPILML_01541 7.88e-24 - - - S - - - PD-(D/E)XK nuclease family transposase
CMLPILML_01542 2.53e-206 - - - S - - - Aldo/keto reductase family
CMLPILML_01543 1.26e-172 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CMLPILML_01544 8.74e-155 dak 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
CMLPILML_01545 4.15e-162 dgk2 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
CMLPILML_01546 1.45e-303 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
CMLPILML_01547 6.61e-295 pbuG - - S ko:K06901 - ko00000,ko02000 permease
CMLPILML_01549 1.78e-162 - - - K - - - helix_turn_helix, mercury resistance
CMLPILML_01550 5.76e-296 pbuG - - S ko:K06901 - ko00000,ko02000 permease
CMLPILML_01551 1.58e-60 - - - I - - - bis(5'-adenosyl)-triphosphatase activity
CMLPILML_01552 7.1e-293 pbuG - - S ko:K06901 - ko00000,ko02000 permease
CMLPILML_01553 8.45e-92 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
CMLPILML_01554 1.37e-116 - - - - - - - -
CMLPILML_01555 2.26e-117 - - - - - - - -
CMLPILML_01556 3.09e-102 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Penicillinase repressor
CMLPILML_01557 4.35e-86 - - - S - - - Cupredoxin-like domain
CMLPILML_01558 6.31e-65 - - - S - - - Cupredoxin-like domain
CMLPILML_01559 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
CMLPILML_01560 3.17e-200 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix XRE-family like proteins
CMLPILML_01561 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
CMLPILML_01562 0.0 - - - E - - - Amino acid permease
CMLPILML_01563 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
CMLPILML_01564 1.67e-315 ynbB - - P - - - aluminum resistance
CMLPILML_01565 1.13e-98 - - - K - - - Acetyltransferase (GNAT) domain
CMLPILML_01566 2.63e-296 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
CMLPILML_01567 7.94e-90 - - - S - - - Iron-sulphur cluster biosynthesis
CMLPILML_01568 0.0 mutS1 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CMLPILML_01569 1.98e-149 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
CMLPILML_01570 9.66e-138 - - - - - - - -
CMLPILML_01571 3.24e-196 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional regulator
CMLPILML_01572 7.78e-267 - - - EGP - - - Major facilitator Superfamily
CMLPILML_01573 0.0 eriC - - P ko:K03281 - ko00000 chloride
CMLPILML_01574 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CMLPILML_01575 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
CMLPILML_01576 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CMLPILML_01577 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CMLPILML_01578 1.7e-201 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CMLPILML_01579 3.62e-79 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CMLPILML_01580 6.59e-23 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
CMLPILML_01581 0.0 - - - M - - - Rib/alpha-like repeat
CMLPILML_01582 7.94e-202 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
CMLPILML_01583 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CMLPILML_01584 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
CMLPILML_01585 2.22e-206 - - - EG - - - EamA-like transporter family
CMLPILML_01586 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
CMLPILML_01587 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
CMLPILML_01588 1.73e-89 - - - - - - - -
CMLPILML_01589 1.2e-30 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CMLPILML_01590 4.41e-116 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CMLPILML_01591 2.47e-275 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
CMLPILML_01592 3.52e-303 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CMLPILML_01593 4.63e-169 - - - S - - - PAS domain
CMLPILML_01594 5.83e-205 - - - S - - - PD-(D/E)XK nuclease family transposase
CMLPILML_01595 1.29e-69 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
CMLPILML_01596 3.06e-06 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CMLPILML_01597 0.0 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CMLPILML_01598 1.7e-188 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
CMLPILML_01599 1.83e-124 - - - S - - - PAS domain
CMLPILML_01600 3.53e-314 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
CMLPILML_01601 1.16e-97 - - - S - - - Protein of unknown function (DUF3290)
CMLPILML_01602 7.18e-145 yviA - - S - - - Protein of unknown function (DUF421)
CMLPILML_01603 5.38e-180 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CMLPILML_01604 1.2e-236 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 EXOIII
CMLPILML_01605 6.36e-257 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
CMLPILML_01606 1.43e-97 dkgB - - S - - - reductase
CMLPILML_01607 3.26e-17 dkgB - - S - - - reductase
CMLPILML_01608 1.46e-202 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
CMLPILML_01609 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
CMLPILML_01610 9.81e-259 malK - - P ko:K10112,ko:K17240 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
CMLPILML_01611 4.34e-202 - - - P ko:K02025 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
CMLPILML_01612 3.39e-189 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
CMLPILML_01613 0.0 - - - S - - - Zn-dependent metallo-hydrolase RNA specificity domain
CMLPILML_01614 1.38e-311 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
CMLPILML_01615 7.83e-74 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
CMLPILML_01616 1.84e-100 yybA - - K - - - Transcriptional regulator
CMLPILML_01617 2.29e-125 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
CMLPILML_01618 1.27e-104 yjcF - - S - - - Acetyltransferase (GNAT) domain
CMLPILML_01619 1.59e-214 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
CMLPILML_01620 8.18e-216 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
CMLPILML_01621 3.6e-127 yobS - - K - - - Bacterial regulatory proteins, tetR family
CMLPILML_01622 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
CMLPILML_01623 3.15e-175 - - - S - - - haloacid dehalogenase-like hydrolase
CMLPILML_01624 3.24e-159 - - - S - - - SNARE associated Golgi protein
CMLPILML_01625 1.05e-229 - - - - - - - -
CMLPILML_01626 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
CMLPILML_01627 1.73e-184 plcR - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
CMLPILML_01628 6.43e-196 - - - I - - - alpha/beta hydrolase fold
CMLPILML_01629 1.03e-138 - - - S - - - SNARE associated Golgi protein
CMLPILML_01630 3.29e-132 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
CMLPILML_01631 1.3e-301 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CMLPILML_01632 0.0 ndvA - - V ko:K06147 - ko00000,ko02000 ABC transporter
CMLPILML_01633 2.39e-156 vanR - - K - - - response regulator
CMLPILML_01634 1.85e-264 - - - T - - - His Kinase A (phosphoacceptor) domain
CMLPILML_01635 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CMLPILML_01636 1.29e-184 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
CMLPILML_01637 9.23e-214 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CMLPILML_01638 1.07e-282 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
CMLPILML_01639 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
CMLPILML_01640 4.79e-56 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
CMLPILML_01641 2.29e-175 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
CMLPILML_01642 5.13e-214 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
CMLPILML_01643 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
CMLPILML_01644 0.0 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CMLPILML_01645 2.02e-179 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
CMLPILML_01646 4.8e-57 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
CMLPILML_01647 3.83e-211 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
CMLPILML_01648 2.22e-152 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
CMLPILML_01649 8.87e-174 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
CMLPILML_01650 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
CMLPILML_01652 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
CMLPILML_01653 1.04e-271 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
CMLPILML_01654 5.64e-54 - - - - - - - -
CMLPILML_01655 9.18e-83 - - - - - - - -
CMLPILML_01656 0.0 - - - S - - - ABC transporter, ATP-binding protein
CMLPILML_01657 9.33e-179 - - - S - - - Putative threonine/serine exporter
CMLPILML_01658 1.1e-103 - - - S - - - Threonine/Serine exporter, ThrE
CMLPILML_01659 5.2e-54 - - - - - - - -
CMLPILML_01660 3.75e-79 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
CMLPILML_01661 6.76e-106 - - - - - - - -
CMLPILML_01662 3.52e-232 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CMLPILML_01663 3.86e-107 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
CMLPILML_01664 3.86e-143 - - - - - - - -
CMLPILML_01665 0.0 - - - S - - - O-antigen ligase like membrane protein
CMLPILML_01666 3.52e-58 - - - - - - - -
CMLPILML_01667 5.01e-128 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
CMLPILML_01669 3.06e-194 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
CMLPILML_01670 4.24e-298 - - - S - - - Putative peptidoglycan binding domain
CMLPILML_01671 3.7e-299 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CMLPILML_01672 0.0 - - - E - - - Amino Acid
CMLPILML_01673 4.63e-173 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CMLPILML_01674 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
CMLPILML_01675 6.19e-162 gpm2 - - G - - - Phosphoglycerate mutase family
CMLPILML_01676 6e-35 - - - - - - - -
CMLPILML_01677 5.76e-70 - - - - - - - -
CMLPILML_01678 6.23e-191 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
CMLPILML_01679 0.0 ptsG 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
CMLPILML_01680 1.77e-67 ptsG 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
CMLPILML_01681 2.81e-165 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CMLPILML_01682 1.38e-186 - - - K - - - Helix-turn-helix domain, rpiR family
CMLPILML_01683 4.84e-60 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
CMLPILML_01684 0.0 - - - M - - - ErfK YbiS YcfS YnhG
CMLPILML_01685 4.12e-316 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
CMLPILML_01686 4.02e-208 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
CMLPILML_01688 7.5e-153 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
CMLPILML_01689 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
CMLPILML_01690 9.08e-176 - - - S - - - Peptidase_C39 like family
CMLPILML_01691 1.97e-159 - - - K - - - Helix-turn-helix domain, rpiR family
CMLPILML_01692 4.36e-105 - - - L - - - MgsA AAA+ ATPase C terminal
CMLPILML_01693 3.14e-311 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMLPILML_01694 9.65e-135 - - - E - - - GDSL-like Lipase/Acylhydrolase
CMLPILML_01695 7.9e-212 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
CMLPILML_01696 3.93e-134 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CMLPILML_01697 6.61e-190 yycI - - S - - - YycH protein
CMLPILML_01698 6.41e-193 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
CMLPILML_01699 1.04e-263 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
CMLPILML_01700 3.66e-108 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CMLPILML_01701 2.2e-142 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
CMLPILML_01702 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
CMLPILML_01703 3.01e-124 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
CMLPILML_01704 3.49e-219 - - - K - - - helix_turn_helix, arabinose operon control protein
CMLPILML_01705 5.77e-191 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
CMLPILML_01706 7.65e-125 lemA - - S ko:K03744 - ko00000 LemA family
CMLPILML_01707 4.66e-240 ysdE - - P - - - Citrate transporter
CMLPILML_01708 6.45e-91 - - - S - - - Iron-sulphur cluster biosynthesis
CMLPILML_01709 1.14e-23 - - - - - - - -
CMLPILML_01710 1.57e-199 - - - - - - - -
CMLPILML_01712 4.47e-313 - - - M - - - Glycosyl transferase
CMLPILML_01713 1.09e-272 - - - G - - - Glycosyl hydrolases family 8
CMLPILML_01714 2.61e-153 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
CMLPILML_01715 2.73e-208 - - - L - - - HNH nucleases
CMLPILML_01716 7.38e-177 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
CMLPILML_01717 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
CMLPILML_01718 3.97e-136 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
CMLPILML_01719 5.23e-85 yeaO - - S - - - Protein of unknown function, DUF488
CMLPILML_01720 2.16e-168 terC - - P - - - Integral membrane protein TerC family
CMLPILML_01721 5.26e-123 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 6-O-methylguanine DNA methyltransferase, DNA binding domain
CMLPILML_01722 1.63e-172 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
CMLPILML_01723 1.33e-104 - - - - - - - -
CMLPILML_01724 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CMLPILML_01725 1.81e-159 yugP - - S ko:K06973 - ko00000 Putative neutral zinc metallopeptidase
CMLPILML_01726 2.39e-225 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
CMLPILML_01727 3.86e-187 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CMLPILML_01728 4.75e-219 - - - S - - - Protein of unknown function (DUF1002)
CMLPILML_01729 1.5e-85 - - - M - - - Glycosyltransferase like family 2
CMLPILML_01730 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
CMLPILML_01731 0.0 - - - M - - - domain protein
CMLPILML_01732 0.0 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
CMLPILML_01733 1.37e-220 - - - K - - - LysR substrate binding domain
CMLPILML_01734 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
CMLPILML_01735 1.55e-309 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
CMLPILML_01736 1.1e-170 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
CMLPILML_01737 4.14e-229 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
CMLPILML_01738 1.18e-124 - - - S - - - Peptidase propeptide and YPEB domain
CMLPILML_01739 1.24e-192 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
CMLPILML_01740 1.33e-19 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
CMLPILML_01741 0.0 - - - P - - - Major Facilitator Superfamily
CMLPILML_01742 2.13e-75 - - - P - - - Major Facilitator Superfamily
CMLPILML_01743 2.48e-166 - - - P - - - Major Facilitator Superfamily
CMLPILML_01744 1.42e-211 arbZ - - I - - - Phosphate acyltransferases
CMLPILML_01745 2.51e-236 - - - M - - - Glycosyl transferase family 8
CMLPILML_01746 3.05e-235 - - - M - - - Glycosyl transferase family 8
CMLPILML_01747 9.16e-202 arbx - - M - - - Glycosyl transferase family 8
CMLPILML_01748 7.51e-194 - - - I - - - Acyl-transferase
CMLPILML_01751 3.03e-167 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
CMLPILML_01752 4.37e-119 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CMLPILML_01753 1.8e-134 - - - - - - - -
CMLPILML_01754 1.41e-120 - - - - - - - -
CMLPILML_01755 3.3e-201 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
CMLPILML_01756 7.98e-172 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CMLPILML_01757 1.82e-229 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
CMLPILML_01758 2.49e-110 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
CMLPILML_01759 3.17e-129 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
CMLPILML_01760 3.45e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
CMLPILML_01761 1.25e-264 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
CMLPILML_01762 1.04e-180 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
CMLPILML_01763 5.35e-176 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
CMLPILML_01764 1.71e-266 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
CMLPILML_01765 1.29e-196 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CMLPILML_01766 1.55e-224 ybbR - - S - - - YbbR-like protein
CMLPILML_01767 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CMLPILML_01768 8.42e-191 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
CMLPILML_01769 2.49e-87 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CMLPILML_01770 1.13e-81 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CMLPILML_01771 7.23e-242 - - - S - - - Putative adhesin
CMLPILML_01772 5.95e-149 - - - - - - - -
CMLPILML_01773 1.07e-192 - - - S - - - Alpha/beta hydrolase family
CMLPILML_01774 2.74e-210 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
CMLPILML_01775 5.59e-276 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CMLPILML_01776 1.11e-126 - - - S - - - VanZ like family
CMLPILML_01777 2.13e-171 yebC - - K - - - Transcriptional regulatory protein
CMLPILML_01778 7.04e-230 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
CMLPILML_01779 1.65e-226 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
CMLPILML_01780 4.94e-54 comGC - - U ko:K02245,ko:K02456 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 Required for transformation and DNA binding
CMLPILML_01781 1.45e-88 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
CMLPILML_01783 3.17e-113 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
CMLPILML_01784 1.48e-186 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
CMLPILML_01785 2.51e-33 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
CMLPILML_01786 5.13e-287 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CMLPILML_01788 1.02e-14 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Levansucrase/Invertase
CMLPILML_01789 2.39e-229 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
CMLPILML_01790 1.77e-286 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CMLPILML_01791 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
CMLPILML_01792 1.66e-247 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
CMLPILML_01793 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
CMLPILML_01794 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CMLPILML_01795 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
CMLPILML_01796 1.44e-117 - - - S - - - Short repeat of unknown function (DUF308)
CMLPILML_01797 3.19e-206 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
CMLPILML_01798 1.88e-246 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
CMLPILML_01799 8.24e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
CMLPILML_01800 3.74e-130 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CMLPILML_01801 0.0 ycaM - - E - - - amino acid
CMLPILML_01803 2.15e-237 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
CMLPILML_01804 4.74e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CMLPILML_01805 1.42e-286 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
CMLPILML_01806 8.39e-182 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CMLPILML_01807 1.18e-311 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CMLPILML_01808 1.07e-39 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
CMLPILML_01809 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CMLPILML_01810 7.24e-102 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
CMLPILML_01811 1.38e-138 - - - K ko:K06977 - ko00000 acetyltransferase
CMLPILML_01813 2.49e-201 - - - - - - - -
CMLPILML_01814 5.74e-71 aroD 1.1.1.25, 4.2.1.10 - E ko:K03785,ko:K13832 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 3-dehydroquinate dehydratase activity
CMLPILML_01815 4.62e-223 - - - C - - - Domain of unknown function (DUF4931)
CMLPILML_01816 9.8e-197 - - - K - - - Helix-turn-helix domain, rpiR family
CMLPILML_01817 2.92e-183 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
CMLPILML_01818 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
CMLPILML_01819 6.19e-208 - - - O - - - protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CMLPILML_01820 4.68e-168 - - - - - - - -
CMLPILML_01821 4.81e-69 - - - - - - - -
CMLPILML_01822 3.01e-181 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
CMLPILML_01823 1.58e-138 - - - S - - - Protein of unknown function (DUF975)
CMLPILML_01824 1.53e-181 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
CMLPILML_01825 8.8e-149 - - - G - - - Phosphoglycerate mutase family
CMLPILML_01826 9.98e-146 - - - G - - - phosphoglycerate mutase
CMLPILML_01827 2.72e-119 - - - K - - - Bacterial regulatory proteins, tetR family
CMLPILML_01828 2.91e-234 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
CMLPILML_01829 3.67e-154 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CMLPILML_01830 5.09e-203 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
CMLPILML_01831 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CMLPILML_01832 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
CMLPILML_01833 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
CMLPILML_01834 6.73e-51 - - - - - - - -
CMLPILML_01835 6.92e-141 - - - K - - - WHG domain
CMLPILML_01836 9.4e-128 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
CMLPILML_01837 4.45e-128 azr 1.5.1.36 - S ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
CMLPILML_01838 3.26e-254 - 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
CMLPILML_01839 1.06e-192 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
CMLPILML_01840 1.33e-227 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CMLPILML_01841 1.5e-123 cvpA - - S - - - Colicin V production protein
CMLPILML_01843 1.51e-236 manL 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
CMLPILML_01844 1.23e-166 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
CMLPILML_01845 2.46e-219 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
CMLPILML_01846 4.26e-86 - - - S - - - Domain of unknown function (DUF956)
CMLPILML_01847 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
CMLPILML_01848 1.01e-311 yifK - - E ko:K03293 - ko00000 Amino acid permease
CMLPILML_01849 1.02e-177 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
CMLPILML_01850 6.26e-306 - - - E - - - amino acid
CMLPILML_01851 3.99e-299 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
CMLPILML_01852 6.86e-246 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
CMLPILML_01853 1.52e-207 - - - EG - - - EamA-like transporter family
CMLPILML_01854 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
CMLPILML_01855 8.43e-170 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
CMLPILML_01856 1.38e-192 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
CMLPILML_01857 2.82e-188 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
CMLPILML_01858 1.19e-236 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
CMLPILML_01859 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
CMLPILML_01860 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CMLPILML_01861 1.59e-120 ymdB - - S - - - Macro domain protein
CMLPILML_01862 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
CMLPILML_01863 2.4e-160 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
CMLPILML_01864 1.31e-287 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
CMLPILML_01865 6.11e-129 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
CMLPILML_01866 0.0 - - - S - - - TerB-C domain
CMLPILML_01867 0.0 - - - P - - - P-loop Domain of unknown function (DUF2791)
CMLPILML_01868 0.0 - - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
CMLPILML_01869 1.75e-296 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
CMLPILML_01870 3.99e-256 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
CMLPILML_01871 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
CMLPILML_01872 1.41e-93 - - - - - - - -

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)