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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
DMNEPPOG_00001	3.23e-77	-	-	-	S	-	-	-	SIR2-like domain
DMNEPPOG_00002	0.0	-	-	-	-	-	-	-	-
DMNEPPOG_00003	7.29e-06	-	-	-	-	-	-	-	-
DMNEPPOG_00004	1.55e-10	-	-	-	L	-	-	-	Transposase IS66 family
DMNEPPOG_00005	1.6e-10	-	-	-	L	ko:K07484	-	ko00000	PFAM transposase IS66
DMNEPPOG_00006	2.52e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DMNEPPOG_00007	1.23e-111	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
DMNEPPOG_00008	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DMNEPPOG_00009	6.1e-272	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
DMNEPPOG_00010	6.03e-289	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DMNEPPOG_00011	1.24e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DMNEPPOG_00012	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
DMNEPPOG_00013	6.27e-308	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
DMNEPPOG_00014	1.98e-148	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
DMNEPPOG_00015	8.02e-152	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
DMNEPPOG_00016	4.82e-229	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
DMNEPPOG_00017	3.25e-192	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
DMNEPPOG_00018	1.23e-112	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
DMNEPPOG_00019	2.69e-148	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
DMNEPPOG_00020	8.63e-182	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
DMNEPPOG_00021	4.79e-142	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
DMNEPPOG_00022	3.29e-146	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
DMNEPPOG_00023	2.32e-193	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
DMNEPPOG_00024	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DMNEPPOG_00025	7.11e-60	-	-	-	-	-	-	-	-
DMNEPPOG_00026	1.61e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
DMNEPPOG_00027	1.66e-219	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
DMNEPPOG_00028	1.6e-68	ftsL	-	-	D	-	-	-	cell division protein FtsL
DMNEPPOG_00029	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
DMNEPPOG_00030	1.33e-230	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DMNEPPOG_00031	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DMNEPPOG_00032	4e-259	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DMNEPPOG_00033	3.57e-201	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
DMNEPPOG_00034	1.44e-311	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
DMNEPPOG_00035	3.25e-291	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DMNEPPOG_00036	7.24e-102	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
DMNEPPOG_00037	5.58e-60	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	integral membrane protein
DMNEPPOG_00038	2.14e-188	ylmH	-	-	S	-	-	-	S4 domain protein
DMNEPPOG_00039	1.47e-120	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA protein
DMNEPPOG_00040	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DMNEPPOG_00041	4.62e-48	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
DMNEPPOG_00042	5.93e-207	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
DMNEPPOG_00043	2.64e-307	ydiC1	-	-	EGP	-	-	-	Major Facilitator
DMNEPPOG_00044	7.29e-270	yaaN	-	-	P	-	-	-	Toxic anion resistance protein (TelA)
DMNEPPOG_00045	2.8e-151	-	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
DMNEPPOG_00046	3.03e-123	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
DMNEPPOG_00047	1.42e-39	-	-	-	-	-	-	-	-
DMNEPPOG_00048	1.95e-159	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DMNEPPOG_00049	1.39e-278	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
DMNEPPOG_00050	1.21e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
DMNEPPOG_00051	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
DMNEPPOG_00052	0.0	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
DMNEPPOG_00054	4.69e-159	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
DMNEPPOG_00055	1.62e-151	-	-	-	S	-	-	-	repeat protein
DMNEPPOG_00056	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
DMNEPPOG_00057	2.86e-312	-	-	-	S	-	-	-	Sterol carrier protein domain
DMNEPPOG_00058	4e-233	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
DMNEPPOG_00059	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DMNEPPOG_00060	2.02e-43	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
DMNEPPOG_00061	1.11e-95	-	-	-	-	-	-	-	-
DMNEPPOG_00062	4.23e-64	-	-	-	-	-	-	-	-
DMNEPPOG_00063	4.82e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DMNEPPOG_00064	3.62e-112	-	-	-	S	-	-	-	E1-E2 ATPase
DMNEPPOG_00065	1.42e-267	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
DMNEPPOG_00066	1.15e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
DMNEPPOG_00067	0.0	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
DMNEPPOG_00068	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
DMNEPPOG_00069	3.55e-201	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
DMNEPPOG_00070	6.15e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
DMNEPPOG_00071	3.56e-189	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
DMNEPPOG_00072	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
DMNEPPOG_00073	1.66e-269	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
DMNEPPOG_00074	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DMNEPPOG_00075	8.46e-84	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
DMNEPPOG_00076	9.93e-130	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
DMNEPPOG_00077	1.08e-113	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DMNEPPOG_00078	1.23e-231	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
DMNEPPOG_00079	1.09e-151	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
DMNEPPOG_00080	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
DMNEPPOG_00081	5.08e-222	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
DMNEPPOG_00082	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
DMNEPPOG_00083	5e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DMNEPPOG_00084	3.82e-62	-	-	-	-	-	-	-	-
DMNEPPOG_00085	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DMNEPPOG_00086	3.2e-212	-	-	-	S	-	-	-	Tetratricopeptide repeat
DMNEPPOG_00087	4.73e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DMNEPPOG_00088	0.0	yknV	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
DMNEPPOG_00089	9.55e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
DMNEPPOG_00090	1.19e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DMNEPPOG_00091	2.74e-138	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
DMNEPPOG_00092	2.28e-63	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
DMNEPPOG_00093	3.33e-28	-	-	-	-	-	-	-	-
DMNEPPOG_00094	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
DMNEPPOG_00095	6.58e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DMNEPPOG_00096	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
DMNEPPOG_00097	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
DMNEPPOG_00098	1.6e-217	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
DMNEPPOG_00099	2.78e-170	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
DMNEPPOG_00100	3.37e-309	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DMNEPPOG_00101	0.0	oatA	-	-	I	-	-	-	Acyltransferase
DMNEPPOG_00102	2.71e-233	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
DMNEPPOG_00103	1.83e-183	yqjQ	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
DMNEPPOG_00104	2.47e-65	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
DMNEPPOG_00105	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
DMNEPPOG_00106	1.35e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
DMNEPPOG_00107	6.3e-123	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
DMNEPPOG_00108	0.0	ycjM	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
DMNEPPOG_00109	8.63e-185	-	-	-	-	-	-	-	-
DMNEPPOG_00110	3.31e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
DMNEPPOG_00111	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
DMNEPPOG_00112	2.21e-227	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
DMNEPPOG_00113	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
DMNEPPOG_00114	4.31e-95	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
DMNEPPOG_00115	5.96e-207	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
DMNEPPOG_00116	9.95e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
DMNEPPOG_00117	1.59e-88	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DMNEPPOG_00118	5.33e-160	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DMNEPPOG_00119	8.74e-139	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DMNEPPOG_00120	1.1e-175	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
DMNEPPOG_00121	2.52e-122	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DMNEPPOG_00122	1.16e-60	fer	-	-	C	ko:K05337	-	ko00000	4Fe-4S single cluster domain of Ferredoxin I
DMNEPPOG_00123	2.72e-236	-	-	-	S	-	-	-	Helix-turn-helix domain
DMNEPPOG_00124	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
DMNEPPOG_00125	1.68e-104	-	-	-	M	-	-	-	Lysin motif
DMNEPPOG_00126	2.04e-149	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
DMNEPPOG_00127	1.72e-303	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
DMNEPPOG_00128	7.41e-312	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
DMNEPPOG_00129	1.2e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
DMNEPPOG_00130	8.81e-302	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
DMNEPPOG_00131	8.71e-200	ypjC	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DMNEPPOG_00132	5.31e-284	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
DMNEPPOG_00133	2.95e-110	-	-	-	-	-	-	-	-
DMNEPPOG_00134	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
DMNEPPOG_00135	2.43e-243	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DMNEPPOG_00136	1.22e-117	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DMNEPPOG_00137	1.83e-148	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
DMNEPPOG_00138	2.83e-189	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
DMNEPPOG_00139	8.39e-197	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
DMNEPPOG_00140	3.18e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
DMNEPPOG_00141	4.47e-113	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DMNEPPOG_00142	1.03e-54	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
DMNEPPOG_00143	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
DMNEPPOG_00144	1.3e-52	XK27_02555	-	-	-	-	-	-	-
DMNEPPOG_00146	1.47e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
DMNEPPOG_00147	2.52e-195	-	-	-	K	-	-	-	Helix-turn-helix domain
DMNEPPOG_00149	2.53e-205	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DMNEPPOG_00150	2.49e-179	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DMNEPPOG_00151	9.38e-189	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
DMNEPPOG_00152	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DMNEPPOG_00153	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DMNEPPOG_00154	1.66e-216	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
DMNEPPOG_00155	2.06e-119	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DMNEPPOG_00156	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DMNEPPOG_00157	1.32e-219	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
DMNEPPOG_00158	2.14e-140	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
DMNEPPOG_00159	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DMNEPPOG_00160	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DMNEPPOG_00161	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
DMNEPPOG_00162	2.56e-217	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DMNEPPOG_00163	2.6e-232	-	-	-	K	-	-	-	LysR substrate binding domain
DMNEPPOG_00164	5.59e-221	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
DMNEPPOG_00165	3.63e-270	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
DMNEPPOG_00166	7.18e-79	-	-	-	-	-	-	-	-
DMNEPPOG_00167	0.0	XK27_05700	-	-	V	ko:K02004,ko:K19084	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	FtsX-like permease family
DMNEPPOG_00168	2.68e-176	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
DMNEPPOG_00169	1.09e-222	kinG	-	-	T	-	-	-	Histidine kinase-like ATPases
DMNEPPOG_00170	1.75e-159	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
DMNEPPOG_00171	5.52e-243	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
DMNEPPOG_00172	1.07e-43	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DMNEPPOG_00173	6.04e-94	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DMNEPPOG_00174	2.92e-144	-	-	-	C	-	-	-	Nitroreductase family
DMNEPPOG_00175	2.07e-261	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DMNEPPOG_00176	6.09e-70	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
DMNEPPOG_00177	1.01e-77	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DMNEPPOG_00178	6.05e-171	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
DMNEPPOG_00179	1.37e-160	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DMNEPPOG_00180	4.89e-146	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DMNEPPOG_00181	9.2e-82	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
DMNEPPOG_00182	4.33e-297	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DMNEPPOG_00183	2.06e-144	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
DMNEPPOG_00184	3.67e-276	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DMNEPPOG_00185	3.44e-261	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DMNEPPOG_00186	2.36e-129	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
DMNEPPOG_00187	2.53e-206	-	-	-	S	-	-	-	EDD domain protein, DegV family
DMNEPPOG_00188	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
DMNEPPOG_00189	6.51e-69	-	-	-	S	-	-	-	MazG-like family
DMNEPPOG_00190	1.66e-249	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
DMNEPPOG_00191	2.13e-227	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DMNEPPOG_00192	9.61e-289	bfmBB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
DMNEPPOG_00193	2.14e-234	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
DMNEPPOG_00194	9.14e-239	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
DMNEPPOG_00195	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
DMNEPPOG_00196	3.87e-262	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Acetokinase family
DMNEPPOG_00197	1.74e-190	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Phosphate acetyl/butaryl transferase
DMNEPPOG_00198	2.92e-145	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DMNEPPOG_00199	4.62e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
DMNEPPOG_00200	5.67e-200	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
DMNEPPOG_00201	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
DMNEPPOG_00202	5.32e-267	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
DMNEPPOG_00203	5.35e-307	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
DMNEPPOG_00204	9.29e-230	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
DMNEPPOG_00205	6.67e-299	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
DMNEPPOG_00206	1.05e-125	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DMNEPPOG_00207	6.3e-223	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
DMNEPPOG_00208	2.41e-106	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DMNEPPOG_00209	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
DMNEPPOG_00210	8.5e-61	-	-	-	S	-	-	-	Family of unknown function (DUF5322)
DMNEPPOG_00211	2.37e-91	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
DMNEPPOG_00212	5.13e-144	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
DMNEPPOG_00213	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DMNEPPOG_00214	3.85e-63	-	-	-	-	-	-	-	-
DMNEPPOG_00215	0.0	-	-	-	S	-	-	-	Mga helix-turn-helix domain
DMNEPPOG_00216	8.72e-52	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
DMNEPPOG_00217	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DMNEPPOG_00218	8.83e-242	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DMNEPPOG_00219	4.57e-212	lysR	-	-	K	-	-	-	Transcriptional regulator
DMNEPPOG_00220	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
DMNEPPOG_00221	4.08e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
DMNEPPOG_00222	8.85e-47	-	-	-	-	-	-	-	-
DMNEPPOG_00223	2.2e-223	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
DMNEPPOG_00224	1.33e-277	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
DMNEPPOG_00225	7.09e-88	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
DMNEPPOG_00226	6.54e-138	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
DMNEPPOG_00227	5.12e-157	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
DMNEPPOG_00228	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
DMNEPPOG_00229	5.94e-111	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
DMNEPPOG_00230	7.61e-148	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DMNEPPOG_00231	3.19e-146	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
DMNEPPOG_00232	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
DMNEPPOG_00233	4.67e-279	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
DMNEPPOG_00234	3.5e-112	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
DMNEPPOG_00236	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
DMNEPPOG_00237	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
DMNEPPOG_00238	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
DMNEPPOG_00239	7.89e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
DMNEPPOG_00240	5.43e-231	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
DMNEPPOG_00241	7.89e-245	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
DMNEPPOG_00242	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
DMNEPPOG_00243	9.31e-224	-	-	-	-	-	-	-	-
DMNEPPOG_00244	5.49e-185	-	-	-	-	-	-	-	-
DMNEPPOG_00245	2.32e-79	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
DMNEPPOG_00246	2.03e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
DMNEPPOG_00247	1.4e-191	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DMNEPPOG_00248	1.61e-162	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
DMNEPPOG_00250	9.19e-249	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DMNEPPOG_00251	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DMNEPPOG_00252	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
DMNEPPOG_00253	1.48e-219	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
DMNEPPOG_00254	4.99e-72	-	-	-	-	-	-	-	-
DMNEPPOG_00255	7.92e-74	-	-	-	-	-	-	-	-
DMNEPPOG_00256	7.05e-182	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
DMNEPPOG_00257	1.17e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DMNEPPOG_00258	1.38e-84	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
DMNEPPOG_00259	6.78e-82	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
DMNEPPOG_00260	2.95e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DMNEPPOG_00261	8.02e-230	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
DMNEPPOG_00263	1.81e-88	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
DMNEPPOG_00264	3.98e-29	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
DMNEPPOG_00265	8.44e-199	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
DMNEPPOG_00266	1.74e-210	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DMNEPPOG_00267	3.1e-216	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DMNEPPOG_00268	7.56e-108	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
DMNEPPOG_00269	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
DMNEPPOG_00270	3.25e-311	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
DMNEPPOG_00271	1.59e-47	XK27_04345	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
DMNEPPOG_00272	7.04e-217	-	-	-	C	-	-	-	nadph quinone reductase
DMNEPPOG_00273	1.72e-98	-	-	-	-	-	-	-	-
DMNEPPOG_00274	5.67e-191	-	-	-	K	-	-	-	Helix-turn-helix
DMNEPPOG_00275	0.0	-	-	-	-	-	-	-	-
DMNEPPOG_00276	2.81e-200	-	-	-	V	-	-	-	ABC transporter
DMNEPPOG_00277	2.36e-109	-	-	-	FG	-	-	-	adenosine 5'-monophosphoramidase activity
DMNEPPOG_00278	9.4e-313	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
DMNEPPOG_00279	1.35e-150	-	-	-	J	-	-	-	HAD-hyrolase-like
DMNEPPOG_00280	1.59e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DMNEPPOG_00281	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DMNEPPOG_00282	5.49e-58	-	-	-	-	-	-	-	-
DMNEPPOG_00283	1.27e-169	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
DMNEPPOG_00284	1.74e-222	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
DMNEPPOG_00285	3.49e-113	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
DMNEPPOG_00286	1.54e-144	-	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
DMNEPPOG_00287	2.23e-50	-	-	-	-	-	-	-	-
DMNEPPOG_00288	8.05e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
DMNEPPOG_00289	6.1e-27	-	-	-	-	-	-	-	-
DMNEPPOG_00290	1.72e-64	-	-	-	-	-	-	-	-
DMNEPPOG_00291	9.31e-117	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DMNEPPOG_00293	3.1e-143	-	-	-	S	-	-	-	Flavodoxin-like fold
DMNEPPOG_00294	1.54e-130	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DMNEPPOG_00295	7.25e-200	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	N-formylglutamate amidohydrolase
DMNEPPOG_00296	1.66e-71	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
DMNEPPOG_00297	2.01e-118	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DMNEPPOG_00298	1.7e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DMNEPPOG_00299	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
DMNEPPOG_00300	8.85e-76	-	-	-	-	-	-	-	-
DMNEPPOG_00301	2.05e-109	-	-	-	S	-	-	-	ASCH
DMNEPPOG_00302	1.32e-33	-	-	-	-	-	-	-	-
DMNEPPOG_00303	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DMNEPPOG_00304	3.04e-64	-	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
DMNEPPOG_00305	3.56e-177	-	-	-	V	-	-	-	ABC transporter transmembrane region
DMNEPPOG_00306	9.45e-261	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
DMNEPPOG_00307	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
DMNEPPOG_00308	3.18e-127	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DMNEPPOG_00309	1.6e-246	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
DMNEPPOG_00310	1.46e-286	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
DMNEPPOG_00311	3.65e-224	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
DMNEPPOG_00312	5.47e-211	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DMNEPPOG_00313	4.46e-183	terC	-	-	P	-	-	-	Integral membrane protein TerC family
DMNEPPOG_00314	1.27e-76	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DMNEPPOG_00315	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DMNEPPOG_00316	1.29e-60	ylxQ	-	-	J	-	-	-	ribosomal protein
DMNEPPOG_00317	9.63e-61	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
DMNEPPOG_00318	4.13e-277	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
DMNEPPOG_00319	1.33e-110	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
DMNEPPOG_00320	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DMNEPPOG_00321	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
DMNEPPOG_00322	3.52e-292	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
DMNEPPOG_00323	1.55e-178	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
DMNEPPOG_00324	8.7e-179	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DMNEPPOG_00325	1.73e-121	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
DMNEPPOG_00326	5.86e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
DMNEPPOG_00327	1.63e-200	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DMNEPPOG_00328	2.29e-180	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
DMNEPPOG_00329	5.38e-61	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
DMNEPPOG_00330	2.05e-168	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
DMNEPPOG_00331	1.99e-158	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
DMNEPPOG_00332	9.18e-291	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
DMNEPPOG_00333	4.28e-181	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
DMNEPPOG_00334	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DMNEPPOG_00335	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DMNEPPOG_00336	1.39e-40	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
DMNEPPOG_00337	2.84e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
DMNEPPOG_00338	3.28e-28	-	-	-	-	-	-	-	-
DMNEPPOG_00339	2e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
DMNEPPOG_00340	1.76e-185	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
DMNEPPOG_00341	1.77e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DMNEPPOG_00342	1.55e-51	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
DMNEPPOG_00343	2.97e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
DMNEPPOG_00344	3.06e-303	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DMNEPPOG_00345	1.26e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DMNEPPOG_00347	7.91e-70	-	-	-	-	-	-	-	-
DMNEPPOG_00348	1.5e-231	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DMNEPPOG_00349	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
DMNEPPOG_00350	2.8e-161	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DMNEPPOG_00351	0.0	oppA1	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
DMNEPPOG_00352	1.16e-193	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DMNEPPOG_00353	3.2e-216	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DMNEPPOG_00354	1.62e-228	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
DMNEPPOG_00355	6.03e-247	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
DMNEPPOG_00356	3.21e-49	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DMNEPPOG_00357	1.35e-239	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
DMNEPPOG_00358	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DMNEPPOG_00359	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
DMNEPPOG_00360	5.83e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
DMNEPPOG_00361	2.29e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
DMNEPPOG_00362	1.77e-164	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
DMNEPPOG_00363	4.16e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
DMNEPPOG_00364	5.6e-221	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
DMNEPPOG_00365	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
DMNEPPOG_00366	5.22e-174	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
DMNEPPOG_00367	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DMNEPPOG_00368	1.13e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DMNEPPOG_00369	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DMNEPPOG_00370	9.33e-274	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DMNEPPOG_00371	1.77e-47	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
DMNEPPOG_00372	2.52e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
DMNEPPOG_00373	5.76e-118	-	-	-	S	ko:K07001	-	ko00000	Patatin-like phospholipase
DMNEPPOG_00374	2.71e-66	-	-	-	-	-	-	-	-
DMNEPPOG_00376	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
DMNEPPOG_00377	4.19e-96	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
DMNEPPOG_00378	9.45e-196	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
DMNEPPOG_00379	2.58e-189	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
DMNEPPOG_00380	1.42e-43	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DMNEPPOG_00381	1.1e-295	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DMNEPPOG_00382	6.34e-193	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DMNEPPOG_00383	2.34e-88	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DMNEPPOG_00384	9.44e-99	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
DMNEPPOG_00385	6.06e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DMNEPPOG_00387	3.55e-258	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
DMNEPPOG_00388	1.6e-63	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
DMNEPPOG_00389	1.77e-74	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
DMNEPPOG_00390	5.83e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
DMNEPPOG_00391	1.17e-16	-	-	-	-	-	-	-	-
DMNEPPOG_00392	2.12e-40	-	-	-	-	-	-	-	-
DMNEPPOG_00394	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
DMNEPPOG_00395	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
DMNEPPOG_00396	3.8e-80	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
DMNEPPOG_00397	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
DMNEPPOG_00398	1.41e-305	ynbB	-	-	P	-	-	-	aluminum resistance
DMNEPPOG_00399	5.4e-223	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DMNEPPOG_00400	9.56e-35	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
DMNEPPOG_00401	1.93e-96	yqhL	-	-	P	-	-	-	Rhodanese-like protein
DMNEPPOG_00402	6.56e-228	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
DMNEPPOG_00403	6.79e-55	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
DMNEPPOG_00404	2.3e-158	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
DMNEPPOG_00405	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
DMNEPPOG_00406	0.0	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
DMNEPPOG_00407	8.3e-70	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
DMNEPPOG_00408	2.04e-149	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
DMNEPPOG_00409	1.33e-231	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
DMNEPPOG_00410	1.1e-164	yvqF	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
DMNEPPOG_00411	1.05e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DMNEPPOG_00412	5.69e-147	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
DMNEPPOG_00413	1.82e-265	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DMNEPPOG_00414	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DMNEPPOG_00415	1.24e-259	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DMNEPPOG_00416	1.2e-87	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
DMNEPPOG_00417	3.09e-122	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
DMNEPPOG_00418	4.47e-178	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DMNEPPOG_00419	4.17e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
DMNEPPOG_00420	3.66e-228	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DMNEPPOG_00421	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
DMNEPPOG_00422	1.01e-157	csrR	-	-	K	-	-	-	response regulator
DMNEPPOG_00423	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DMNEPPOG_00424	1.9e-53	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
DMNEPPOG_00425	3.82e-128	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
DMNEPPOG_00426	1.67e-270	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
DMNEPPOG_00427	8.39e-179	yccK	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
DMNEPPOG_00428	1.18e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
DMNEPPOG_00429	3.21e-142	yqeK	-	-	H	-	-	-	Hydrolase, HD family
DMNEPPOG_00430	5.06e-168	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DMNEPPOG_00431	1.13e-64	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
DMNEPPOG_00432	3.02e-262	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
DMNEPPOG_00433	6.63e-127	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
DMNEPPOG_00434	4.11e-222	ykcA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DMNEPPOG_00435	1.59e-242	mhqA_2	-	-	E	ko:K15975	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DMNEPPOG_00436	2.14e-157	mhqD	-	-	S	ko:K06999	-	ko00000	Dienelactone hydrolase family
DMNEPPOG_00437	4.5e-233	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
DMNEPPOG_00438	1.01e-130	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
DMNEPPOG_00439	1.02e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DMNEPPOG_00440	1.13e-36	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
DMNEPPOG_00441	7.46e-101	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DMNEPPOG_00442	2.31e-167	-	-	-	S	-	-	-	SseB protein N-terminal domain
DMNEPPOG_00443	5.3e-70	-	-	-	-	-	-	-	-
DMNEPPOG_00444	2.67e-136	yrgI	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Histidine phosphatase superfamily (branch 1)
DMNEPPOG_00445	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DMNEPPOG_00447	2.02e-219	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
DMNEPPOG_00448	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
DMNEPPOG_00449	2.06e-103	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DMNEPPOG_00450	2.82e-132	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DMNEPPOG_00451	7.86e-207	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
DMNEPPOG_00452	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DMNEPPOG_00453	4.41e-156	ybhL	-	-	S	ko:K06890	-	ko00000	Inhibitor of apoptosis-promoting Bax1
DMNEPPOG_00454	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
DMNEPPOG_00455	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
DMNEPPOG_00456	3.17e-149	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DMNEPPOG_00457	5.32e-73	ytpP	-	-	CO	-	-	-	Thioredoxin
DMNEPPOG_00459	8.13e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
DMNEPPOG_00460	4.51e-189	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
DMNEPPOG_00461	6.39e-279	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
DMNEPPOG_00462	2.4e-172	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DMNEPPOG_00463	1.67e-99	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
DMNEPPOG_00464	2.44e-82	-	-	-	S	-	-	-	YtxH-like protein
DMNEPPOG_00465	5.26e-205	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
DMNEPPOG_00466	8.42e-232	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
DMNEPPOG_00467	1.03e-72	-	-	-	S	-	-	-	Control of competence regulator ComK, YlbF/YmcA
DMNEPPOG_00468	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
DMNEPPOG_00469	7.49e-198	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
DMNEPPOG_00470	4.7e-98	argR1	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
DMNEPPOG_00471	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
DMNEPPOG_00473	1.97e-88	-	-	-	-	-	-	-	-
DMNEPPOG_00474	4.04e-32	-	-	-	-	-	-	-	-
DMNEPPOG_00475	3.67e-227	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate
DMNEPPOG_00476	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
DMNEPPOG_00477	1.44e-157	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
DMNEPPOG_00478	1.13e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
DMNEPPOG_00479	3.42e-178	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
DMNEPPOG_00480	7.88e-121	traP	1.14.99.57, 6.2.1.3	-	S	ko:K01897,ko:K21481	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	heme oxygenase (decyclizing) activity
DMNEPPOG_00481	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
DMNEPPOG_00482	1.33e-176	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
DMNEPPOG_00483	1.57e-159	rrp1	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
DMNEPPOG_00484	9.93e-266	-	-	-	T	ko:K19168	-	ko00000,ko02048	His Kinase A (phosphoacceptor) domain
DMNEPPOG_00485	1.54e-141	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DMNEPPOG_00486	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5	-	P	ko:K01533,ko:K01534	-	ko00000,ko01000	P-type ATPase
DMNEPPOG_00487	1.17e-100	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
DMNEPPOG_00488	4.69e-301	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
DMNEPPOG_00489	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
DMNEPPOG_00490	1.37e-129	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DMNEPPOG_00491	7.52e-239	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
DMNEPPOG_00492	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DMNEPPOG_00493	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DMNEPPOG_00494	3.05e-168	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DMNEPPOG_00495	7.25e-56	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DMNEPPOG_00496	1.63e-172	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
DMNEPPOG_00497	6.06e-274	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DMNEPPOG_00498	2.66e-102	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DMNEPPOG_00499	6.68e-136	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
DMNEPPOG_00500	0.0	iolT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
DMNEPPOG_00501	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DMNEPPOG_00502	1.02e-51	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
DMNEPPOG_00503	9.5e-39	-	-	-	-	-	-	-	-
DMNEPPOG_00504	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
DMNEPPOG_00505	3.36e-61	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
DMNEPPOG_00506	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DMNEPPOG_00507	1.44e-311	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
DMNEPPOG_00508	4.17e-262	yueF	-	-	S	-	-	-	AI-2E family transporter
DMNEPPOG_00509	1.13e-97	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
DMNEPPOG_00510	1.11e-122	-	-	-	-	-	-	-	-
DMNEPPOG_00511	1.1e-134	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
DMNEPPOG_00512	3.39e-183	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
DMNEPPOG_00513	0.0	frvR	-	-	K	ko:K02538,ko:K03483,ko:K09685,ko:K18531	-	ko00000,ko03000	transcriptional antiterminator
DMNEPPOG_00514	6.46e-83	-	-	-	-	-	-	-	-
DMNEPPOG_00515	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DMNEPPOG_00516	6.85e-103	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
DMNEPPOG_00517	2.13e-172	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
DMNEPPOG_00518	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DMNEPPOG_00519	0.0	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DMNEPPOG_00520	2.36e-111	-	-	-	-	-	-	-	-
DMNEPPOG_00521	1.94e-66	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
DMNEPPOG_00522	6.27e-67	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DMNEPPOG_00523	0.0	poxL	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
DMNEPPOG_00524	2.6e-279	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
DMNEPPOG_00525	1.63e-267	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
DMNEPPOG_00526	1.41e-265	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
DMNEPPOG_00527	4.19e-65	-	-	-	-	-	-	-	-
DMNEPPOG_00528	2.34e-205	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
DMNEPPOG_00529	4.44e-134	-	-	-	V	ko:K07448	-	ko00000,ko02048	Restriction endonuclease
DMNEPPOG_00530	2.25e-201	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	converts alpha-aldose to the beta-anomer
DMNEPPOG_00531	1.88e-272	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
DMNEPPOG_00532	4.33e-132	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
DMNEPPOG_00534	1.4e-105	-	-	-	K	-	-	-	Acetyltransferase GNAT Family
DMNEPPOG_00535	1.65e-111	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
DMNEPPOG_00536	2.36e-167	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DMNEPPOG_00537	2.83e-188	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
DMNEPPOG_00538	4.78e-196	XK27_08835	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
DMNEPPOG_00539	2.88e-96	-	-	-	-	-	-	-	-
DMNEPPOG_00540	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
DMNEPPOG_00541	1.14e-276	-	-	-	V	-	-	-	Beta-lactamase
DMNEPPOG_00542	2.51e-195	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
DMNEPPOG_00543	5.25e-279	-	-	-	V	-	-	-	Beta-lactamase
DMNEPPOG_00544	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DMNEPPOG_00545	1.62e-161	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
DMNEPPOG_00546	1.01e-264	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DMNEPPOG_00547	1.13e-177	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DMNEPPOG_00548	0.0	yuxL	3.4.19.1	-	E	ko:K01303	-	ko00000,ko01000,ko01002	Prolyl oligopeptidase family
DMNEPPOG_00551	2.53e-204	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
DMNEPPOG_00552	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
DMNEPPOG_00553	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DMNEPPOG_00554	1.71e-87	-	-	-	-	-	-	-	-
DMNEPPOG_00555	8.71e-100	-	-	-	S	-	-	-	function, without similarity to other proteins
DMNEPPOG_00556	0.0	-	-	-	G	-	-	-	MFS/sugar transport protein
DMNEPPOG_00557	4.07e-296	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
DMNEPPOG_00558	8.15e-77	-	-	-	-	-	-	-	-
DMNEPPOG_00559	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
DMNEPPOG_00560	6.28e-25	-	-	-	S	-	-	-	Virus attachment protein p12 family
DMNEPPOG_00561	1.27e-139	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
DMNEPPOG_00562	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
DMNEPPOG_00563	1.01e-88	-	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA
DMNEPPOG_00564	4.08e-168	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
DMNEPPOG_00565	8.73e-282	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
DMNEPPOG_00566	1.77e-87	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
DMNEPPOG_00567	2.46e-56	-	-	-	-	-	-	-	-
DMNEPPOG_00569	2.79e-44	-	-	-	-	-	-	-	-
DMNEPPOG_00570	0.0	-	-	-	S	-	-	-	cellulase activity
DMNEPPOG_00571	0.0	-	-	-	S	-	-	-	Phage tail protein
DMNEPPOG_00572	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
DMNEPPOG_00573	2.72e-27	-	-	-	-	-	-	-	-
DMNEPPOG_00574	7.99e-93	-	-	-	S	-	-	-	Pfam:Phage_TTP_1
DMNEPPOG_00575	1.01e-35	-	-	-	-	-	-	-	-
DMNEPPOG_00576	9.05e-85	-	-	-	S	-	-	-	exonuclease activity
DMNEPPOG_00577	1.38e-52	-	-	-	S	-	-	-	Phage head-tail joining protein
DMNEPPOG_00578	4.38e-36	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
DMNEPPOG_00579	1.76e-36	-	-	-	S	-	-	-	peptidase activity
DMNEPPOG_00580	9.86e-263	-	-	-	S	-	-	-	peptidase activity
DMNEPPOG_00581	1.06e-145	-	-	-	S	-	-	-	peptidase activity
DMNEPPOG_00582	6.95e-301	-	-	-	S	-	-	-	Phage portal protein
DMNEPPOG_00584	1.13e-143	-	-	-	S	-	-	-	Phage Terminase
DMNEPPOG_00585	9.22e-133	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
DMNEPPOG_00586	1.03e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
DMNEPPOG_00587	1.89e-157	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
DMNEPPOG_00588	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
DMNEPPOG_00589	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
DMNEPPOG_00590	1.33e-166	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
DMNEPPOG_00591	9.15e-45	yhcC	-	-	S	ko:K07069	-	ko00000	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
DMNEPPOG_00592	3.37e-183	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DMNEPPOG_00593	4.57e-124	-	-	-	F	-	-	-	NUDIX domain
DMNEPPOG_00595	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
DMNEPPOG_00596	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
DMNEPPOG_00597	9.78e-112	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
DMNEPPOG_00600	7.73e-299	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
DMNEPPOG_00601	0.0	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
DMNEPPOG_00602	5.05e-52	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
DMNEPPOG_00603	6.79e-313	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
DMNEPPOG_00604	1.21e-272	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
DMNEPPOG_00605	1.15e-150	yjbH	-	-	Q	-	-	-	Thioredoxin
DMNEPPOG_00606	4.21e-137	-	-	-	S	-	-	-	CYTH
DMNEPPOG_00607	1.19e-158	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
DMNEPPOG_00608	1.05e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DMNEPPOG_00609	1e-218	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
DMNEPPOG_00610	4.86e-259	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DMNEPPOG_00611	2.24e-148	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
DMNEPPOG_00612	2.39e-187	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
DMNEPPOG_00613	6.58e-254	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
DMNEPPOG_00614	2e-82	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
DMNEPPOG_00615	4.12e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DMNEPPOG_00616	2.45e-245	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DMNEPPOG_00617	1.94e-219	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
DMNEPPOG_00618	1.46e-201	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
DMNEPPOG_00619	3.21e-125	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
DMNEPPOG_00620	4.04e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
DMNEPPOG_00621	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
DMNEPPOG_00622	9.41e-296	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
DMNEPPOG_00623	2.38e-310	ymfH	-	-	S	-	-	-	Peptidase M16
DMNEPPOG_00624	3.01e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
DMNEPPOG_00625	1.15e-169	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
DMNEPPOG_00626	3.46e-136	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DMNEPPOG_00627	3.67e-294	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
DMNEPPOG_00628	1.59e-244	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DMNEPPOG_00629	7.95e-317	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
DMNEPPOG_00630	5.06e-152	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
DMNEPPOG_00631	2.84e-302	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
DMNEPPOG_00632	4.32e-104	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
DMNEPPOG_00633	3.24e-126	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DMNEPPOG_00634	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DMNEPPOG_00635	1.23e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DMNEPPOG_00636	1.28e-160	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	ABC transporter
DMNEPPOG_00637	9.02e-199	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
DMNEPPOG_00638	7.77e-259	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
DMNEPPOG_00639	5.24e-168	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
DMNEPPOG_00640	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
DMNEPPOG_00641	4.5e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
DMNEPPOG_00642	4.48e-205	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
DMNEPPOG_00643	1.06e-201	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
DMNEPPOG_00644	1.57e-192	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DMNEPPOG_00645	2.49e-180	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DMNEPPOG_00646	3.82e-156	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
DMNEPPOG_00647	0.0	yvlB	-	-	S	-	-	-	Putative adhesin
DMNEPPOG_00648	5.23e-50	-	-	-	-	-	-	-	-
DMNEPPOG_00649	3.07e-50	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
DMNEPPOG_00650	8.27e-223	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DMNEPPOG_00651	7.94e-202	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DMNEPPOG_00652	6.29e-250	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
DMNEPPOG_00653	3.41e-230	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
DMNEPPOG_00654	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
DMNEPPOG_00655	1.51e-148	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
DMNEPPOG_00656	4.14e-225	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
DMNEPPOG_00657	6.97e-117	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
DMNEPPOG_00658	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
DMNEPPOG_00659	1.99e-153	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
DMNEPPOG_00660	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DMNEPPOG_00661	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
DMNEPPOG_00662	1.04e-110	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
DMNEPPOG_00663	8.53e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
DMNEPPOG_00664	2.99e-248	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
DMNEPPOG_00665	2.88e-221	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
DMNEPPOG_00666	7.84e-106	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
DMNEPPOG_00667	5.97e-132	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DMNEPPOG_00669	1.05e-271	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DMNEPPOG_00670	6.34e-105	-	-	-	-	-	-	-	-
DMNEPPOG_00671	7.6e-176	-	-	-	L	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
DMNEPPOG_00672	5.99e-154	-	-	-	P	ko:K10716	-	ko00000,ko02000	Ion transport protein
DMNEPPOG_00673	3.75e-98	-	-	-	E	-	-	-	Zn peptidase
DMNEPPOG_00674	1.9e-72	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DMNEPPOG_00676	1.39e-183	-	-	-	K	-	-	-	ORF6N domain
DMNEPPOG_00677	4.68e-77	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
DMNEPPOG_00680	9.66e-30	-	-	-	-	-	-	-	-
DMNEPPOG_00683	5.34e-108	-	-	-	S	-	-	-	Siphovirus Gp157
DMNEPPOG_00685	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
DMNEPPOG_00686	3.13e-170	-	-	-	L	-	-	-	AAA domain
DMNEPPOG_00687	4.05e-119	-	-	-	-	-	-	-	-
DMNEPPOG_00688	1.84e-192	-	-	-	L	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
DMNEPPOG_00689	5.84e-289	-	-	-	S	ko:K06919	-	ko00000	Virulence-associated protein E
DMNEPPOG_00690	4e-54	-	-	-	-	-	-	-	-
DMNEPPOG_00692	1.47e-136	-	-	-	S	-	-	-	HNH endonuclease
DMNEPPOG_00694	1.66e-92	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
DMNEPPOG_00695	1.64e-86	-	-	-	V	-	-	-	HNH endonuclease
DMNEPPOG_00696	2.02e-82	-	-	-	-	-	-	-	-
DMNEPPOG_00697	0.0	-	-	-	S	-	-	-	overlaps another CDS with the same product name
DMNEPPOG_00698	5.91e-299	-	-	-	S	-	-	-	Phage portal protein
DMNEPPOG_00699	1.38e-163	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
DMNEPPOG_00700	6.24e-270	-	-	-	S	-	-	-	Phage capsid family
DMNEPPOG_00702	9.08e-71	-	-	-	-	-	-	-	-
DMNEPPOG_00703	3.92e-76	-	-	-	S	-	-	-	Phage head-tail joining protein
DMNEPPOG_00704	1.28e-75	-	-	-	-	-	-	-	-
DMNEPPOG_00705	2.6e-88	-	-	-	-	-	-	-	-
DMNEPPOG_00706	2.71e-151	-	-	-	-	-	-	-	-
DMNEPPOG_00707	5.81e-80	-	-	-	-	-	-	-	-
DMNEPPOG_00708	0.0	-	-	-	D	-	-	-	Phage tail tape measure protein
DMNEPPOG_00709	6.59e-160	-	-	-	S	-	-	-	phage tail
DMNEPPOG_00710	0.0	-	-	-	LM	-	-	-	gp58-like protein
DMNEPPOG_00711	4.83e-93	-	-	-	-	-	-	-	-
DMNEPPOG_00712	1.62e-53	-	-	-	-	-	-	-	-
DMNEPPOG_00713	9.57e-60	-	-	-	-	-	-	-	-
DMNEPPOG_00714	2.9e-71	hol	-	-	S	-	-	-	Bacteriophage holin
DMNEPPOG_00715	2.06e-259	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
DMNEPPOG_00717	5.52e-241	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
DMNEPPOG_00718	2.1e-247	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DMNEPPOG_00719	2.16e-282	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
DMNEPPOG_00720	2.81e-180	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DMNEPPOG_00721	2.05e-313	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DMNEPPOG_00722	6.34e-294	mdt(A)	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
DMNEPPOG_00723	1.33e-63	-	-	-	-	-	-	-	-
DMNEPPOG_00724	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
DMNEPPOG_00725	5.04e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
DMNEPPOG_00726	2.82e-181	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
DMNEPPOG_00727	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
DMNEPPOG_00728	4.47e-108	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
DMNEPPOG_00729	9.37e-228	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
DMNEPPOG_00730	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
DMNEPPOG_00731	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
DMNEPPOG_00732	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
DMNEPPOG_00733	1e-154	-	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
DMNEPPOG_00734	3.2e-268	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
DMNEPPOG_00735	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
DMNEPPOG_00736	6.27e-289	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
DMNEPPOG_00737	1.48e-306	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DMNEPPOG_00738	6.34e-194	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DMNEPPOG_00739	1.09e-21	-	-	-	-	-	-	-	-
DMNEPPOG_00740	7.06e-36	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
DMNEPPOG_00741	8.2e-308	YSH1	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Metallo-beta-lactamase superfamily
DMNEPPOG_00742	8.67e-312	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
DMNEPPOG_00743	1.1e-188	malF	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DMNEPPOG_00744	7.01e-213	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
DMNEPPOG_00745	3.08e-248	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
DMNEPPOG_00746	3.63e-136	-	-	-	K	ko:K06977	-	ko00000	Acetyltransferase (GNAT) domain
DMNEPPOG_00747	7.57e-119	-	-	-	-	-	-	-	-
DMNEPPOG_00748	4e-203	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
DMNEPPOG_00749	1.45e-166	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DMNEPPOG_00750	3.02e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
DMNEPPOG_00751	1.35e-107	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
DMNEPPOG_00753	1.6e-214	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DMNEPPOG_00754	1.27e-275	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
DMNEPPOG_00755	8.04e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
DMNEPPOG_00756	8.14e-194	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
DMNEPPOG_00757	4.74e-213	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
DMNEPPOG_00758	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
DMNEPPOG_00759	1.97e-124	-	-	-	K	-	-	-	Cupin domain
DMNEPPOG_00760	9.1e-263	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
DMNEPPOG_00761	5.86e-189	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DMNEPPOG_00762	2.88e-187	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DMNEPPOG_00763	8.49e-267	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DMNEPPOG_00765	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
DMNEPPOG_00766	2.42e-144	-	-	-	K	-	-	-	Transcriptional regulator
DMNEPPOG_00767	9.79e-243	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
DMNEPPOG_00768	8.98e-169	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
DMNEPPOG_00769	3.82e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DMNEPPOG_00770	1.58e-216	ybbR	-	-	S	-	-	-	YbbR-like protein
DMNEPPOG_00771	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DMNEPPOG_00772	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DMNEPPOG_00774	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
DMNEPPOG_00775	3.35e-106	-	-	-	S	-	-	-	VanZ like family
DMNEPPOG_00776	5.85e-169	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
DMNEPPOG_00777	2.43e-196	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
DMNEPPOG_00778	7.91e-219	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
DMNEPPOG_00779	1e-35	-	-	-	-	ko:K02245	-	ko00000,ko00002,ko02044	-
DMNEPPOG_00781	8.98e-30	-	-	-	-	-	-	-	-
DMNEPPOG_00782	2.01e-24	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
DMNEPPOG_00784	3.73e-239	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
DMNEPPOG_00785	2.1e-81	-	-	-	-	-	-	-	-
DMNEPPOG_00786	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
DMNEPPOG_00787	7.51e-191	arbV	-	-	I	-	-	-	Phosphate acyltransferases
DMNEPPOG_00788	1.94e-210	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
DMNEPPOG_00789	2.41e-235	arbY	-	-	M	-	-	-	family 8
DMNEPPOG_00790	9.24e-214	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
DMNEPPOG_00791	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
DMNEPPOG_00793	1.43e-273	sip	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DMNEPPOG_00794	4.17e-06	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
DMNEPPOG_00796	1.39e-40	-	-	-	-	-	-	-	-
DMNEPPOG_00797	6.39e-25	-	-	-	-	-	-	-	-
DMNEPPOG_00798	1.17e-30	-	-	-	-	-	-	-	-
DMNEPPOG_00800	5.47e-33	-	-	-	-	-	-	-	-
DMNEPPOG_00801	1.96e-188	-	-	-	L	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
DMNEPPOG_00802	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
DMNEPPOG_00803	6.31e-68	-	-	-	S	-	-	-	Phage head-tail joining protein
DMNEPPOG_00805	1.5e-27	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	COG1403 Restriction endonuclease
DMNEPPOG_00806	3.15e-103	terS	-	-	L	-	-	-	Phage terminase, small subunit
DMNEPPOG_00807	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
DMNEPPOG_00808	8.61e-29	-	-	-	-	-	-	-	-
DMNEPPOG_00809	6.65e-280	-	-	-	S	-	-	-	Phage portal protein
DMNEPPOG_00810	0.0	-	-	-	S	ko:K06904	-	ko00000	Phage capsid family
DMNEPPOG_00811	1.64e-282	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DMNEPPOG_00812	4.24e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
DMNEPPOG_00813	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
DMNEPPOG_00814	1.69e-218	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
DMNEPPOG_00815	8.63e-254	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
DMNEPPOG_00818	2.36e-111	-	2.7.1.204	-	G	ko:K20112	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DMNEPPOG_00819	2.68e-67	-	2.7.1.204	-	G	ko:K20113	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DMNEPPOG_00820	0.0	gatC	-	-	G	ko:K20114	ko02060,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
DMNEPPOG_00821	9.83e-37	-	-	-	-	-	-	-	-
DMNEPPOG_00822	1.98e-163	-	-	-	S	-	-	-	Domain of unknown function (DUF4867)
DMNEPPOG_00823	4.29e-226	lacC	2.7.1.144	-	H	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
DMNEPPOG_00824	1.78e-240	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
DMNEPPOG_00825	4.53e-122	lacB	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
DMNEPPOG_00826	1.25e-96	lacA	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
DMNEPPOG_00827	4.13e-181	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
DMNEPPOG_00828	3.73e-150	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
DMNEPPOG_00829	3.37e-272	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
DMNEPPOG_00830	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
DMNEPPOG_00831	6.8e-21	-	-	-	-	-	-	-	-
DMNEPPOG_00832	7.42e-112	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
DMNEPPOG_00834	1.26e-271	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
DMNEPPOG_00835	3.17e-191	-	-	-	I	-	-	-	alpha/beta hydrolase fold
DMNEPPOG_00836	1.06e-156	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
DMNEPPOG_00838	1.83e-113	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
DMNEPPOG_00839	1.92e-153	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
DMNEPPOG_00840	9.5e-199	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
DMNEPPOG_00841	3.35e-252	-	-	-	-	-	-	-	-
DMNEPPOG_00843	1.39e-149	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
DMNEPPOG_00844	0.0	bglB	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
DMNEPPOG_00845	6.45e-215	XK27_00670	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
DMNEPPOG_00846	5.08e-214	XK27_00670	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter
DMNEPPOG_00847	6.83e-208	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
DMNEPPOG_00848	1.17e-180	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DMNEPPOG_00849	3.01e-225	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
DMNEPPOG_00850	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
DMNEPPOG_00851	8.07e-233	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferase family 2
DMNEPPOG_00852	0.0	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
DMNEPPOG_00853	1.53e-93	-	-	-	S	-	-	-	GtrA-like protein
DMNEPPOG_00854	3.91e-159	ciaR	-	-	K	ko:K14983	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
DMNEPPOG_00855	3.66e-310	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
DMNEPPOG_00856	2.42e-88	-	-	-	S	-	-	-	Belongs to the HesB IscA family
DMNEPPOG_00857	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
DMNEPPOG_00858	1.12e-208	-	-	-	S	-	-	-	KR domain
DMNEPPOG_00859	1.71e-205	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
DMNEPPOG_00860	1.77e-158	ydgI	-	-	C	-	-	-	Nitroreductase family
DMNEPPOG_00861	9.14e-263	lldD	1.13.12.4	-	C	ko:K00467	ko00620,map00620	ko00000,ko00001,ko01000	IMP dehydrogenase / GMP reductase domain
DMNEPPOG_00864	7.9e-246	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
DMNEPPOG_00865	1.17e-77	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
DMNEPPOG_00866	2.7e-62	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
DMNEPPOG_00867	4.91e-55	-	-	-	-	-	-	-	-
DMNEPPOG_00868	2.45e-246	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
DMNEPPOG_00869	2.56e-69	-	-	-	-	-	-	-	-
DMNEPPOG_00870	1.79e-104	-	-	-	-	-	-	-	-
DMNEPPOG_00871	5.77e-267	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
DMNEPPOG_00872	1.58e-33	-	-	-	-	-	-	-	-
DMNEPPOG_00873	9.86e-146	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DMNEPPOG_00874	4.2e-65	-	-	-	-	-	-	-	-
DMNEPPOG_00875	5.96e-214	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
DMNEPPOG_00876	1.69e-115	-	-	-	S	-	-	-	Flavin reductase like domain
DMNEPPOG_00877	9.67e-91	-	-	-	-	-	-	-	-
DMNEPPOG_00878	6.56e-131	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DMNEPPOG_00879	1.7e-81	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
DMNEPPOG_00880	2.2e-223	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
DMNEPPOG_00881	5.29e-205	mleR	-	-	K	-	-	-	LysR family
DMNEPPOG_00882	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
DMNEPPOG_00883	3.58e-217	mleP	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
DMNEPPOG_00884	8.23e-117	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DMNEPPOG_00885	2.28e-113	-	-	-	C	-	-	-	FMN binding
DMNEPPOG_00886	1.09e-222	-	-	-	K	ko:K20373,ko:K20374	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
DMNEPPOG_00887	1.01e-306	-	-	-	V	-	-	-	ABC transporter transmembrane region
DMNEPPOG_00888	0.0	pepF	-	-	E	-	-	-	Oligopeptidase F
DMNEPPOG_00889	9.47e-79	-	-	-	-	-	-	-	-
DMNEPPOG_00890	3.81e-170	-	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
DMNEPPOG_00891	3.34e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
DMNEPPOG_00892	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
DMNEPPOG_00893	2.7e-231	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	carboxylic ester hydrolase activity
DMNEPPOG_00894	1.69e-58	-	-	-	-	-	-	-	-
DMNEPPOG_00895	1.64e-120	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DMNEPPOG_00896	3.96e-256	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
DMNEPPOG_00897	7.46e-157	XK27_05175	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
DMNEPPOG_00898	2.24e-101	-	-	-	K	-	-	-	Transcriptional regulator
DMNEPPOG_00899	2.4e-231	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
DMNEPPOG_00900	2.69e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
DMNEPPOG_00901	4.36e-200	dkgB	-	-	S	-	-	-	reductase
DMNEPPOG_00902	4.98e-203	-	-	-	-	-	-	-	-
DMNEPPOG_00903	6.16e-199	-	-	-	S	-	-	-	Alpha beta hydrolase
DMNEPPOG_00904	7.76e-152	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
DMNEPPOG_00905	3.69e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
DMNEPPOG_00906	4.87e-283	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
DMNEPPOG_00907	1.69e-112	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
DMNEPPOG_00908	1.3e-136	yjbF	-	-	S	-	-	-	SNARE associated Golgi protein
DMNEPPOG_00909	2.95e-133	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
DMNEPPOG_00910	1.59e-241	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
DMNEPPOG_00911	4.54e-264	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DMNEPPOG_00912	3.46e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
DMNEPPOG_00913	4.49e-88	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
DMNEPPOG_00914	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
DMNEPPOG_00915	2.06e-150	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
DMNEPPOG_00916	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DMNEPPOG_00917	1.25e-264	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DMNEPPOG_00918	1.13e-307	ytoI	-	-	K	-	-	-	DRTGG domain
DMNEPPOG_00919	3.03e-229	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
DMNEPPOG_00920	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
DMNEPPOG_00921	1.88e-224	-	-	-	-	-	-	-	-
DMNEPPOG_00922	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DMNEPPOG_00924	4.89e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
DMNEPPOG_00925	2.67e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DMNEPPOG_00926	1.3e-69	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
DMNEPPOG_00927	2.84e-48	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DMNEPPOG_00928	3.4e-120	cvpA	-	-	S	-	-	-	Colicin V production protein
DMNEPPOG_00929	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
DMNEPPOG_00930	3.64e-70	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
DMNEPPOG_00931	1.04e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
DMNEPPOG_00932	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DMNEPPOG_00933	9.86e-304	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
DMNEPPOG_00934	6.97e-49	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DMNEPPOG_00935	2.48e-313	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DMNEPPOG_00936	2.02e-112	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
DMNEPPOG_00937	0.0	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
DMNEPPOG_00938	1.15e-125	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
DMNEPPOG_00939	1.9e-175	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Major intrinsic protein
DMNEPPOG_00940	9.32e-112	ykuL	-	-	S	-	-	-	CBS domain
DMNEPPOG_00941	3.55e-203	-	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
DMNEPPOG_00942	6.86e-198	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
DMNEPPOG_00943	1.49e-46	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DMNEPPOG_00944	4.84e-114	ytxH	-	-	S	-	-	-	YtxH-like protein
DMNEPPOG_00945	7.49e-117	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
DMNEPPOG_00946	2.2e-274	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
DMNEPPOG_00947	3.03e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
DMNEPPOG_00948	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin binding protein transpeptidase domain
DMNEPPOG_00949	1.06e-163	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
DMNEPPOG_00950	5.87e-177	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
DMNEPPOG_00951	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
DMNEPPOG_00952	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
DMNEPPOG_00953	9.98e-73	-	-	-	-	-	-	-	-
DMNEPPOG_00954	1.2e-240	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
DMNEPPOG_00955	3.82e-150	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
DMNEPPOG_00956	8.94e-146	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
DMNEPPOG_00957	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
DMNEPPOG_00958	1.77e-151	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
DMNEPPOG_00959	1.34e-186	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
DMNEPPOG_00960	6.43e-146	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
DMNEPPOG_00961	8.69e-149	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
DMNEPPOG_00962	2.26e-115	pgpA	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phosphatidylglycerophosphatase A
DMNEPPOG_00963	1.92e-237	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
DMNEPPOG_00964	4.42e-142	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DMNEPPOG_00965	1.17e-82	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
DMNEPPOG_00966	5.31e-82	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
DMNEPPOG_00967	3.23e-225	-	-	-	S	-	-	-	Membrane
DMNEPPOG_00968	1.07e-144	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
DMNEPPOG_00969	2.45e-182	-	-	-	K	-	-	-	SIS domain
DMNEPPOG_00970	5.22e-153	rpiA1	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
DMNEPPOG_00971	3.31e-237	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
DMNEPPOG_00972	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DMNEPPOG_00974	2.65e-139	-	-	-	-	-	-	-	-
DMNEPPOG_00975	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
DMNEPPOG_00976	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
DMNEPPOG_00977	4.83e-98	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DMNEPPOG_00978	2.21e-181	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DMNEPPOG_00979	5.04e-127	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
DMNEPPOG_00981	1.73e-247	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
DMNEPPOG_00982	2.3e-158	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	Rossmann-like domain
DMNEPPOG_00984	4.29e-228	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
DMNEPPOG_00985	1.03e-127	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
DMNEPPOG_00986	2.76e-104	-	-	-	S	-	-	-	NusG domain II
DMNEPPOG_00987	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
DMNEPPOG_00988	6.86e-187	cad	-	-	S	ko:K20379	ko02024,map02024	ko00000,ko00001	FMN_bind
DMNEPPOG_00989	2.2e-252	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DMNEPPOG_00990	2.73e-213	menA	2.5.1.74	-	M	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
DMNEPPOG_00991	1.53e-218	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
DMNEPPOG_00992	2.09e-30	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
DMNEPPOG_00993	2.29e-130	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
DMNEPPOG_00994	6.98e-205	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
DMNEPPOG_00995	3.77e-102	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
DMNEPPOG_00996	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
DMNEPPOG_00997	4.31e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
DMNEPPOG_00998	7.87e-125	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
DMNEPPOG_00999	1.25e-119	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobalamin adenosyltransferase
DMNEPPOG_01000	5.78e-85	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
DMNEPPOG_01001	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
DMNEPPOG_01002	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
DMNEPPOG_01003	6.87e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DMNEPPOG_01004	1.89e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
DMNEPPOG_01005	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
DMNEPPOG_01006	1.19e-277	yceI	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
DMNEPPOG_01007	4.02e-86	-	-	-	-	-	-	-	-
DMNEPPOG_01008	8.22e-198	-	-	-	K	-	-	-	acetyltransferase
DMNEPPOG_01009	1.92e-283	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
DMNEPPOG_01010	7.23e-108	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DMNEPPOG_01011	1.37e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
DMNEPPOG_01012	4.18e-206	-	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
DMNEPPOG_01013	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
DMNEPPOG_01014	3.52e-224	ccpB	-	-	K	-	-	-	lacI family
DMNEPPOG_01015	3.3e-59	-	-	-	-	-	-	-	-
DMNEPPOG_01016	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DMNEPPOG_01017	1.65e-139	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
DMNEPPOG_01018	9.05e-67	-	-	-	-	-	-	-	-
DMNEPPOG_01019	4.38e-118	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
DMNEPPOG_01020	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DMNEPPOG_01021	7e-49	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DMNEPPOG_01022	5.12e-139	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DMNEPPOG_01023	2.95e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
DMNEPPOG_01024	7.2e-151	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DMNEPPOG_01025	1.14e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
DMNEPPOG_01026	2.28e-223	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
DMNEPPOG_01027	7.92e-76	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
DMNEPPOG_01028	1.49e-192	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DMNEPPOG_01029	3.86e-185	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
DMNEPPOG_01030	1.24e-231	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
DMNEPPOG_01031	8.11e-116	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
DMNEPPOG_01032	4.18e-96	-	-	-	-	-	-	-	-
DMNEPPOG_01033	3.82e-168	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
DMNEPPOG_01034	8.44e-130	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
DMNEPPOG_01035	5.99e-243	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DMNEPPOG_01036	3.12e-68	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DMNEPPOG_01037	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
DMNEPPOG_01038	1.1e-151	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DMNEPPOG_01039	4.97e-81	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
DMNEPPOG_01040	5.68e-202	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DMNEPPOG_01041	4.68e-236	-	-	-	-	-	-	-	-
DMNEPPOG_01042	2.03e-251	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
DMNEPPOG_01043	6.1e-143	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DMNEPPOG_01044	1.7e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DMNEPPOG_01045	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
DMNEPPOG_01046	2.17e-74	-	-	-	S	-	-	-	Domain of unknown function (DUF1827)
DMNEPPOG_01047	0.0	ydaO	-	-	E	-	-	-	amino acid
DMNEPPOG_01048	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DMNEPPOG_01049	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DMNEPPOG_01050	3.95e-127	maf	-	-	D	ko:K06287	-	ko00000	nucleoside-triphosphate diphosphatase activity
DMNEPPOG_01051	8.38e-80	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
DMNEPPOG_01052	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
DMNEPPOG_01053	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
DMNEPPOG_01054	1.5e-173	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
DMNEPPOG_01055	2.34e-152	-	-	-	F	-	-	-	glutamine amidotransferase
DMNEPPOG_01056	1.02e-138	-	-	-	T	-	-	-	Sh3 type 3 domain protein
DMNEPPOG_01057	6.56e-131	-	-	-	Q	-	-	-	methyltransferase
DMNEPPOG_01059	1.31e-146	-	-	-	GM	-	-	-	NmrA-like family
DMNEPPOG_01060	1.37e-246	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
DMNEPPOG_01061	6.85e-103	-	-	-	C	-	-	-	Flavodoxin
DMNEPPOG_01062	5.77e-93	adhR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
DMNEPPOG_01063	4.1e-112	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
DMNEPPOG_01064	2.19e-84	-	-	-	-	-	-	-	-
DMNEPPOG_01065	4.33e-283	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Domain of unknown function (DUF1730)
DMNEPPOG_01066	6.37e-187	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
DMNEPPOG_01067	3.25e-74	-	-	-	K	-	-	-	Helix-turn-helix domain
DMNEPPOG_01068	9.59e-101	usp5	-	-	T	-	-	-	universal stress protein
DMNEPPOG_01069	2.84e-143	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
DMNEPPOG_01070	5.74e-212	-	-	-	EG	-	-	-	EamA-like transporter family
DMNEPPOG_01071	6.71e-34	-	-	-	-	-	-	-	-
DMNEPPOG_01072	4.98e-112	-	-	-	-	-	-	-	-
DMNEPPOG_01073	6.98e-53	-	-	-	-	-	-	-	-
DMNEPPOG_01074	3.09e-244	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DMNEPPOG_01075	2.86e-304	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
DMNEPPOG_01076	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
DMNEPPOG_01077	2.5e-233	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
DMNEPPOG_01078	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
DMNEPPOG_01079	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DMNEPPOG_01080	6.43e-66	-	-	-	-	-	-	-	-
DMNEPPOG_01081	4.58e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
DMNEPPOG_01082	7.63e-275	-	-	-	S	-	-	-	Membrane
DMNEPPOG_01083	6.56e-181	-	-	-	-	-	-	-	-
DMNEPPOG_01084	8.2e-210	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
DMNEPPOG_01085	4.3e-96	-	-	-	S	-	-	-	NusG domain II
DMNEPPOG_01086	4.81e-230	cydD1	-	-	CO	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
DMNEPPOG_01087	6.64e-133	cydD1	-	-	CO	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
DMNEPPOG_01088	0.0	msbA9	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
DMNEPPOG_01089	1.13e-73	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
DMNEPPOG_01090	8.77e-57	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
DMNEPPOG_01091	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
DMNEPPOG_01092	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DMNEPPOG_01093	2.02e-126	-	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Bacterial regulatory proteins, tetR family
DMNEPPOG_01094	2.64e-316	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
DMNEPPOG_01095	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
DMNEPPOG_01096	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
DMNEPPOG_01097	3.4e-82	-	-	-	S	-	-	-	Coenzyme PQQ synthesis protein D (PqqD)
DMNEPPOG_01098	0.0	-	-	-	S	-	-	-	OPT oligopeptide transporter protein
DMNEPPOG_01099	1.06e-238	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DMNEPPOG_01100	8.36e-257	ald1	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
DMNEPPOG_01101	5.9e-187	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	reductase
DMNEPPOG_01103	3.76e-10	-	-	-	S	-	-	-	YopX protein
DMNEPPOG_01106	1.4e-94	-	-	-	-	-	-	-	-
DMNEPPOG_01110	1.49e-275	-	-	-	S	-	-	-	GcrA cell cycle regulator
DMNEPPOG_01113	2.95e-120	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
DMNEPPOG_01114	1.88e-314	-	-	-	S	-	-	-	Terminase-like family
DMNEPPOG_01115	0.0	-	-	-	S	-	-	-	Phage portal protein
DMNEPPOG_01116	5.21e-229	-	-	-	S	-	-	-	head morphogenesis protein, SPP1 gp7 family
DMNEPPOG_01118	6.1e-110	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
DMNEPPOG_01119	1.17e-62	-	-	-	-	-	-	-	-
DMNEPPOG_01120	3.07e-239	-	-	-	S	-	-	-	Phage major capsid protein E
DMNEPPOG_01121	4.62e-195	-	-	-	-	-	-	-	-
DMNEPPOG_01122	6.46e-83	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
DMNEPPOG_01123	3.85e-66	-	-	-	-	-	-	-	-
DMNEPPOG_01124	6.78e-60	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
DMNEPPOG_01125	1.59e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF3168)
DMNEPPOG_01126	1.5e-124	-	-	-	S	-	-	-	Phage tail tube protein
DMNEPPOG_01127	1.33e-64	-	-	-	S	-	-	-	Phage tail assembly chaperone protein, TAC
DMNEPPOG_01128	2.6e-72	-	-	-	-	-	-	-	-
DMNEPPOG_01129	0.0	-	-	-	S	-	-	-	phage tail tape measure protein
DMNEPPOG_01130	0.0	-	-	-	S	-	-	-	Phage tail protein
DMNEPPOG_01131	0.0	-	-	-	S	-	-	-	cellulase activity
DMNEPPOG_01132	9.87e-70	-	-	-	-	-	-	-	-
DMNEPPOG_01134	1.07e-58	-	-	-	-	-	-	-	-
DMNEPPOG_01135	3.84e-82	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
DMNEPPOG_01136	3.78e-270	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
DMNEPPOG_01137	2.4e-185	-	-	-	S	-	-	-	Domain of unknown function DUF1829
DMNEPPOG_01138	2.12e-63	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
DMNEPPOG_01140	1.69e-197	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
DMNEPPOG_01141	3.92e-103	-	-	-	S	-	-	-	Pfam Transposase IS66
DMNEPPOG_01142	6.79e-295	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferases group 1
DMNEPPOG_01143	1.09e-220	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
DMNEPPOG_01144	9.82e-111	guaD	-	-	FJ	-	-	-	MafB19-like deaminase
DMNEPPOG_01146	5.18e-104	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
DMNEPPOG_01147	1.53e-19	-	-	-	-	-	-	-	-
DMNEPPOG_01148	3.25e-273	yttB	-	-	EGP	-	-	-	Major Facilitator
DMNEPPOG_01149	6.19e-136	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
DMNEPPOG_01150	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
DMNEPPOG_01153	2.58e-166	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
DMNEPPOG_01154	6.41e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DMNEPPOG_01155	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
DMNEPPOG_01156	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
DMNEPPOG_01157	1.29e-181	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
DMNEPPOG_01158	1.36e-210	catE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
DMNEPPOG_01159	9.13e-252	ampC	-	-	V	-	-	-	Beta-lactamase
DMNEPPOG_01160	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
DMNEPPOG_01161	7.61e-144	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
DMNEPPOG_01162	8.62e-252	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DMNEPPOG_01163	2.32e-196	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
DMNEPPOG_01164	1.2e-238	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
DMNEPPOG_01165	1.57e-298	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DMNEPPOG_01166	3.05e-145	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DMNEPPOG_01167	1.23e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
DMNEPPOG_01168	2.57e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DMNEPPOG_01169	1.13e-83	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DMNEPPOG_01170	3.37e-117	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DMNEPPOG_01171	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DMNEPPOG_01172	1.92e-211	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DMNEPPOG_01173	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DMNEPPOG_01174	1.88e-91	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
DMNEPPOG_01175	8.38e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
DMNEPPOG_01176	4.12e-228	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
DMNEPPOG_01177	1.37e-26	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
DMNEPPOG_01178	1.14e-72	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
DMNEPPOG_01179	8.37e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
DMNEPPOG_01180	1.16e-284	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
DMNEPPOG_01181	4.19e-65	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
DMNEPPOG_01182	3.19e-284	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
DMNEPPOG_01183	1.88e-186	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
DMNEPPOG_01184	8.04e-192	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
DMNEPPOG_01185	3.46e-242	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DMNEPPOG_01186	9.25e-150	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DMNEPPOG_01187	4.15e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
DMNEPPOG_01188	3.88e-243	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
DMNEPPOG_01189	7.86e-286	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DMNEPPOG_01190	4.94e-103	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
DMNEPPOG_01191	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
DMNEPPOG_01192	4.73e-31	-	-	-	-	-	-	-	-
DMNEPPOG_01193	9.85e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
DMNEPPOG_01194	3.03e-231	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
DMNEPPOG_01195	1.29e-150	yhfA	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
DMNEPPOG_01196	3.15e-199	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DMNEPPOG_01197	5.76e-108	uspA	-	-	T	-	-	-	universal stress protein
DMNEPPOG_01198	9.94e-54	-	-	-	-	-	-	-	-
DMNEPPOG_01200	1.66e-306	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
DMNEPPOG_01201	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
DMNEPPOG_01202	1.17e-100	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
DMNEPPOG_01203	5.99e-143	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
DMNEPPOG_01204	1.02e-158	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
DMNEPPOG_01205	1.61e-193	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
DMNEPPOG_01206	4.65e-158	-	-	-	G	-	-	-	alpha-ribazole phosphatase activity
DMNEPPOG_01207	7.23e-200	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DMNEPPOG_01208	1.49e-221	-	-	-	IQ	-	-	-	NAD dependent epimerase/dehydratase family
DMNEPPOG_01209	2.93e-178	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
DMNEPPOG_01210	2.05e-173	-	-	-	F	-	-	-	deoxynucleoside kinase
DMNEPPOG_01211	4.04e-203	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphatase and related hydrolases of the PHP family
DMNEPPOG_01212	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
DMNEPPOG_01213	1.24e-202	-	-	-	T	-	-	-	GHKL domain
DMNEPPOG_01214	2.21e-155	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
DMNEPPOG_01215	1.17e-217	bcrA	-	-	V	ko:K01990,ko:K19309	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
DMNEPPOG_01216	4.43e-143	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
DMNEPPOG_01217	1.2e-206	-	-	-	K	-	-	-	Transcriptional regulator
DMNEPPOG_01218	9.46e-103	yphH	-	-	S	-	-	-	Cupin domain
DMNEPPOG_01219	1.07e-72	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
DMNEPPOG_01220	2.72e-149	-	-	-	GM	-	-	-	NAD(P)H-binding
DMNEPPOG_01221	1.94e-54	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
DMNEPPOG_01222	4.73e-158	gst	2.5.1.18	-	O	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	ko00000,ko00001,ko01000,ko02000	Glutathione S-transferase, C-terminal domain
DMNEPPOG_01223	2.07e-149	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
DMNEPPOG_01224	7.95e-219	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DMNEPPOG_01225	3.03e-115	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DMNEPPOG_01226	5.91e-199	degV	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
DMNEPPOG_01227	2.07e-135	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
DMNEPPOG_01228	2.43e-264	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
DMNEPPOG_01229	1.17e-169	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
DMNEPPOG_01230	5.68e-202	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
DMNEPPOG_01231	3.71e-280	-	-	-	-	-	-	-	-
DMNEPPOG_01232	2.65e-89	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
DMNEPPOG_01233	4.87e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
DMNEPPOG_01234	2.31e-88	-	-	-	S	-	-	-	Protein of unknown function C-terminus (DUF2399)
DMNEPPOG_01235	3.69e-46	-	-	-	S	-	-	-	Protein of unknown function C-terminus (DUF2399)
DMNEPPOG_01236	5.07e-157	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DMNEPPOG_01237	1.23e-57	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
DMNEPPOG_01238	8.76e-63	-	-	-	S	-	-	-	ParE toxin of type II toxin-antitoxin system, parDE
DMNEPPOG_01240	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
DMNEPPOG_01242	5.34e-64	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
DMNEPPOG_01243	5.16e-66	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DMNEPPOG_01244	0.0	bgl	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DMNEPPOG_01245	1.45e-202	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
DMNEPPOG_01246	0.0	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
DMNEPPOG_01247	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
DMNEPPOG_01248	1.54e-307	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DMNEPPOG_01249	1.1e-172	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
DMNEPPOG_01251	3.7e-176	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
DMNEPPOG_01253	0.0	pts36C	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
DMNEPPOG_01254	4.54e-70	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DMNEPPOG_01255	1.89e-110	pts36A	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DMNEPPOG_01256	1.62e-186	rdrB	-	-	K	ko:K02444,ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
DMNEPPOG_01257	4.06e-209	-	-	-	J	-	-	-	Methyltransferase domain
DMNEPPOG_01258	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
DMNEPPOG_01261	8.33e-182	-	-	-	M	-	-	-	Right handed beta helix region
DMNEPPOG_01262	1.32e-224	-	-	-	M	-	-	-	Right handed beta helix region
DMNEPPOG_01263	3.76e-96	-	-	-	-	-	-	-	-
DMNEPPOG_01264	0.0	-	-	-	M	-	-	-	Heparinase II/III N-terminus
DMNEPPOG_01266	6.89e-107	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
DMNEPPOG_01267	1.43e-183	agaD	-	-	G	ko:K02747	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
DMNEPPOG_01268	6.84e-186	-	-	-	G	ko:K02746	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
DMNEPPOG_01269	1.72e-114	-	-	-	G	ko:K02745	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
DMNEPPOG_01270	8.01e-301	ugl	3.2.1.180	GH88	S	ko:K18581	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
DMNEPPOG_01271	4.54e-203	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
DMNEPPOG_01272	1.1e-179	-	-	-	K	-	-	-	Bacterial transcriptional regulator
DMNEPPOG_01273	3.75e-209	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
DMNEPPOG_01274	6.38e-193	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DMNEPPOG_01275	2.82e-154	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
DMNEPPOG_01276	8.25e-249	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
DMNEPPOG_01277	4.7e-156	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
DMNEPPOG_01278	7.16e-163	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DMNEPPOG_01279	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DMNEPPOG_01280	2.46e-221	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
DMNEPPOG_01281	1.56e-154	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatase
DMNEPPOG_01282	2.8e-150	-	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
DMNEPPOG_01283	1.8e-316	kinE	-	-	T	-	-	-	Histidine kinase
DMNEPPOG_01284	1.62e-161	llrE	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
DMNEPPOG_01285	0.0	-	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
DMNEPPOG_01286	0.0	-	2.7.1.199, 2.7.1.208	-	G	ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
DMNEPPOG_01287	0.0	hylB	4.2.2.1	PL8	N	ko:K01727	-	ko00000,ko01000	Polysaccharide lyase family 8, N terminal alpha-helical domain
DMNEPPOG_01288	0.0	-	-	-	-	-	-	-	-
DMNEPPOG_01289	3.3e-144	-	-	-	-	-	-	-	-
DMNEPPOG_01290	6.42e-112	-	-	-	-	-	-	-	-
DMNEPPOG_01291	7.05e-175	-	-	-	K	-	-	-	M protein trans-acting positive regulator
DMNEPPOG_01292	3.39e-156	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
DMNEPPOG_01293	6.05e-108	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
DMNEPPOG_01294	3.33e-265	-	-	-	S	-	-	-	DUF218 domain
DMNEPPOG_01295	5.63e-177	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
DMNEPPOG_01296	1.06e-260	selA	2.9.1.1	-	H	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	L-seryl-tRNA selenium transferase
DMNEPPOG_01297	3.82e-278	dho	3.5.2.3	-	S	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase family
DMNEPPOG_01298	3.79e-155	-	-	-	S	-	-	-	Domain of unknown function (DUF4310)
DMNEPPOG_01299	4.1e-177	-	-	-	S	-	-	-	Domain of unknown function (DUF4311)
DMNEPPOG_01300	1.57e-76	-	-	-	S	-	-	-	Domain of unknown function (DUF4312)
DMNEPPOG_01301	8.65e-81	-	-	-	S	-	-	-	Glycine-rich SFCGS
DMNEPPOG_01302	5.21e-74	-	-	-	S	-	-	-	PRD domain
DMNEPPOG_01303	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
DMNEPPOG_01304	7.18e-160	-	-	-	H	-	-	-	Pfam:Transaldolase
DMNEPPOG_01305	2.24e-84	-	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
DMNEPPOG_01306	3.58e-262	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
DMNEPPOG_01307	5.81e-131	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
DMNEPPOG_01308	2.63e-115	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
DMNEPPOG_01309	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
DMNEPPOG_01310	4.13e-185	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
DMNEPPOG_01311	1.57e-177	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
DMNEPPOG_01312	2.51e-194	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
DMNEPPOG_01313	1.53e-212	sga	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
DMNEPPOG_01314	8.64e-178	-	-	-	K	-	-	-	DeoR C terminal sensor domain
DMNEPPOG_01315	3.17e-149	ulaD	4.1.1.85, 4.1.2.43	-	G	ko:K03078,ko:K08093	ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
DMNEPPOG_01316	3.36e-61	sgaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DMNEPPOG_01317	0.0	sgaT	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
DMNEPPOG_01318	4.89e-105	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DMNEPPOG_01319	4.59e-275	ulaG	-	-	S	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Beta-lactamase superfamily domain
DMNEPPOG_01320	2.92e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DMNEPPOG_01321	3.14e-254	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
DMNEPPOG_01322	4.13e-118	-	-	-	G	-	-	-	DeoC/LacD family aldolase
DMNEPPOG_01323	1.15e-154	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
DMNEPPOG_01324	1.29e-201	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
DMNEPPOG_01325	1.95e-172	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
DMNEPPOG_01326	2.79e-107	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
DMNEPPOG_01327	1.23e-95	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
DMNEPPOG_01328	8.79e-263	-	1.1.1.405	-	E	ko:K05352	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
DMNEPPOG_01329	1.67e-173	-	-	-	K	-	-	-	DeoR C terminal sensor domain
DMNEPPOG_01330	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
DMNEPPOG_01331	1.27e-143	-	-	-	GK	-	-	-	ROK family
DMNEPPOG_01332	4.75e-48	-	-	-	GK	-	-	-	ROK family
DMNEPPOG_01333	7.76e-233	asnA2	3.5.1.1	-	E	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
DMNEPPOG_01334	0.0	-	-	-	E	-	-	-	Peptidase family M20/M25/M40
DMNEPPOG_01335	1.23e-168	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
DMNEPPOG_01336	0.0	-	4.1.1.12	-	E	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	ko00000,ko00001,ko01000	Aminotransferase
DMNEPPOG_01337	1.67e-272	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
DMNEPPOG_01338	4.17e-265	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
DMNEPPOG_01339	1.07e-93	-	-	-	S	-	-	-	Domain of unknown function (DUF4428)
DMNEPPOG_01340	0.0	-	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
DMNEPPOG_01341	1.63e-259	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
DMNEPPOG_01342	1.29e-197	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
DMNEPPOG_01343	3.52e-176	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
DMNEPPOG_01344	2.3e-106	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
DMNEPPOG_01345	1.03e-92	ahaA	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
DMNEPPOG_01346	0.0	-	-	-	K	ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DMNEPPOG_01347	6.68e-177	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
DMNEPPOG_01348	1.14e-167	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
DMNEPPOG_01349	1.72e-216	-	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
DMNEPPOG_01350	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
DMNEPPOG_01351	5.44e-175	-	-	-	K	-	-	-	UTRA domain
DMNEPPOG_01352	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DMNEPPOG_01353	2.36e-167	rpl	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
DMNEPPOG_01354	1.88e-223	fruK-1	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
DMNEPPOG_01355	0.0	fruC	2.7.1.202	-	GT	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DMNEPPOG_01356	5.24e-116	-	-	-	-	-	-	-	-
DMNEPPOG_01357	4.42e-154	ydfK	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
DMNEPPOG_01358	2.13e-246	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DMNEPPOG_01359	5.71e-58	-	-	-	L	ko:K07483	-	ko00000	Homeodomain-like domain
DMNEPPOG_01360	5.11e-178	-	-	-	L	-	-	-	COG2801 Transposase and inactivated derivatives
DMNEPPOG_01361	0.0	-	-	-	EGP	-	-	-	Major Facilitator
DMNEPPOG_01362	6.04e-291	-	-	-	EK	-	-	-	Aminotransferase, class I
DMNEPPOG_01363	1.08e-213	-	-	-	K	-	-	-	LysR substrate binding domain
DMNEPPOG_01364	1.38e-117	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DMNEPPOG_01365	7.22e-197	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
DMNEPPOG_01366	1.56e-161	gpmB	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
DMNEPPOG_01367	8.43e-139	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
DMNEPPOG_01368	4.9e-17	-	-	-	-	-	-	-	-
DMNEPPOG_01369	4.04e-79	-	-	-	-	-	-	-	-
DMNEPPOG_01370	5.86e-187	-	-	-	S	-	-	-	hydrolase
DMNEPPOG_01371	7.61e-247	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
DMNEPPOG_01372	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
DMNEPPOG_01373	1.91e-93	-	-	-	K	-	-	-	MarR family
DMNEPPOG_01374	3.62e-149	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
DMNEPPOG_01376	5.68e-148	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DMNEPPOG_01377	1.6e-222	ydiA	-	-	P	ko:K11041	ko05150,map05150	ko00000,ko00001,ko02042	Voltage-dependent anion channel
DMNEPPOG_01378	2.93e-195	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
DMNEPPOG_01379	0.0	-	-	-	L	-	-	-	DNA helicase
DMNEPPOG_01381	0.0	choS	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
DMNEPPOG_01382	6.07e-225	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
DMNEPPOG_01383	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
DMNEPPOG_01385	1.3e-255	-	-	-	V	-	-	-	efflux transmembrane transporter activity
DMNEPPOG_01386	1.48e-246	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
DMNEPPOG_01387	8.42e-135	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
DMNEPPOG_01388	8.78e-158	-	-	-	S	ko:K06872	-	ko00000	TPM domain
DMNEPPOG_01389	9.66e-307	dinF	-	-	V	-	-	-	MatE
DMNEPPOG_01390	2.76e-120	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
DMNEPPOG_01391	5.94e-198	-	-	-	Q	-	-	-	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
DMNEPPOG_01392	1.74e-224	ydhF	-	-	S	-	-	-	Aldo keto reductase
DMNEPPOG_01393	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
DMNEPPOG_01394	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DMNEPPOG_01395	2.57e-223	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
DMNEPPOG_01396	1.32e-202	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
DMNEPPOG_01397	4.7e-50	-	-	-	-	-	-	-	-
DMNEPPOG_01398	3.21e-125	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
DMNEPPOG_01400	1.32e-218	-	-	-	-	-	-	-	-
DMNEPPOG_01401	6.41e-24	-	-	-	-	-	-	-	-
DMNEPPOG_01402	1.9e-163	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
DMNEPPOG_01403	9.14e-139	yiiE	-	-	S	-	-	-	Protein of unknown function (DUF1211)
DMNEPPOG_01404	3.11e-218	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
DMNEPPOG_01405	1.04e-115	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
DMNEPPOG_01406	2.42e-195	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
DMNEPPOG_01407	1.18e-222	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
DMNEPPOG_01408	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DMNEPPOG_01409	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
DMNEPPOG_01410	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
DMNEPPOG_01411	8.8e-210	-	-	-	T	-	-	-	GHKL domain
DMNEPPOG_01412	8.65e-162	-	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
DMNEPPOG_01413	1.49e-221	yqhA	-	-	G	-	-	-	Aldose 1-epimerase
DMNEPPOG_01414	1.35e-239	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
DMNEPPOG_01415	2.57e-104	manR	2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204	-	G	ko:K02538,ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112	ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	phosphoenolpyruvate-dependent sugar phosphotransferase system
DMNEPPOG_01416	9.1e-190	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
DMNEPPOG_01417	6.78e-130	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DMNEPPOG_01418	1.01e-202	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
DMNEPPOG_01419	4.13e-51	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
DMNEPPOG_01420	6.63e-232	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DMNEPPOG_01421	1.4e-205	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
DMNEPPOG_01422	5.89e-158	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
DMNEPPOG_01423	2.24e-155	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DMNEPPOG_01424	1.01e-193	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
DMNEPPOG_01425	1.79e-286	ysaA	-	-	V	-	-	-	RDD family
DMNEPPOG_01426	3.29e-299	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DMNEPPOG_01427	2.2e-225	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DMNEPPOG_01428	2.57e-35	-	-	-	-	-	-	-	-
DMNEPPOG_01429	3.78e-74	nudA	-	-	S	-	-	-	ASCH
DMNEPPOG_01430	4.82e-104	-	-	-	E	-	-	-	glutamate:sodium symporter activity
DMNEPPOG_01431	1.31e-77	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
DMNEPPOG_01432	2.14e-237	-	-	-	S	-	-	-	DUF218 domain
DMNEPPOG_01433	3.75e-40	mutT	3.5.4.33, 3.6.1.13, 3.6.1.55	-	L	ko:K01515,ko:K03574,ko:K11991	ko00230,map00230	ko00000,ko00001,ko01000,ko03016,ko03400	nUDIX hydrolase
DMNEPPOG_01434	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
DMNEPPOG_01435	4.89e-201	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
DMNEPPOG_01436	4.23e-104	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
DMNEPPOG_01437	1.15e-111	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
DMNEPPOG_01438	3.42e-202	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
DMNEPPOG_01439	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
DMNEPPOG_01440	9.48e-300	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DMNEPPOG_01441	6.55e-57	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
DMNEPPOG_01442	3.58e-300	int	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DMNEPPOG_01444	5.8e-83	-	-	-	-	-	-	-	-
DMNEPPOG_01445	9.81e-138	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
DMNEPPOG_01446	1.21e-48	-	-	-	-	-	-	-	-
DMNEPPOG_01447	8.08e-229	-	-	-	C	-	-	-	Cytochrome bd terminal oxidase subunit II
DMNEPPOG_01448	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit I
DMNEPPOG_01450	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
DMNEPPOG_01451	3.26e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DMNEPPOG_01452	1.54e-114	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
DMNEPPOG_01453	1.36e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
DMNEPPOG_01454	5.2e-98	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
DMNEPPOG_01455	5.22e-163	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DMNEPPOG_01456	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DMNEPPOG_01457	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DMNEPPOG_01458	9.09e-260	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DMNEPPOG_01459	4.07e-43	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
DMNEPPOG_01461	1.02e-260	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
DMNEPPOG_01462	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DMNEPPOG_01463	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
DMNEPPOG_01464	2.99e-77	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
DMNEPPOG_01465	4.53e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DMNEPPOG_01466	1.73e-171	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
DMNEPPOG_01468	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DMNEPPOG_01469	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
DMNEPPOG_01471	3.8e-175	labL	-	-	S	-	-	-	Putative threonine/serine exporter
DMNEPPOG_01472	1.48e-104	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
DMNEPPOG_01473	5.35e-289	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
DMNEPPOG_01474	2.7e-256	ypjH	-	-	C	ko:K08317	-	ko00000,ko01000	dehydrogenase
DMNEPPOG_01475	0.0	-	-	-	M	-	-	-	Leucine rich repeats (6 copies)
DMNEPPOG_01476	1.77e-220	-	-	-	M	-	-	-	Leucine rich repeats (6 copies)
DMNEPPOG_01477	2.53e-265	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
DMNEPPOG_01478	7.13e-161	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
DMNEPPOG_01479	8.41e-195	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMNEPPOG_01480	6.72e-19	-	-	-	-	-	-	-	-
DMNEPPOG_01481	5.93e-59	-	-	-	-	-	-	-	-
DMNEPPOG_01482	3.86e-192	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
DMNEPPOG_01483	2.05e-168	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DMNEPPOG_01484	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DMNEPPOG_01485	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
DMNEPPOG_01486	9.2e-101	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DMNEPPOG_01487	1.61e-273	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
DMNEPPOG_01488	1.25e-237	lipA	-	-	I	-	-	-	Carboxylesterase family
DMNEPPOG_01489	1.56e-231	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
DMNEPPOG_01490	3.23e-218	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DMNEPPOG_01492	7.05e-219	-	-	-	O	-	-	-	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DMNEPPOG_01493	2.35e-286	yagE	-	-	E	-	-	-	Amino acid permease
DMNEPPOG_01494	3.72e-85	-	-	-	-	-	-	-	-
DMNEPPOG_01495	5.33e-124	M1-431	-	-	S	-	-	-	Protein of unknown function (DUF1706)
DMNEPPOG_01496	6.61e-196	-	-	-	I	-	-	-	NAD binding domain of 6-phosphogluconate dehydrogenase
DMNEPPOG_01497	2.69e-158	malR	-	-	KT	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
DMNEPPOG_01498	0.0	dpiB	2.7.13.3	-	T	ko:K02476,ko:K11614	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Single cache domain 3
DMNEPPOG_01499	1.07e-150	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	2-hydroxycarboxylate transporter family
DMNEPPOG_01500	6.09e-116	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	2-hydroxycarboxylate transporter family
DMNEPPOG_01501	1.09e-273	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
DMNEPPOG_01502	5.19e-62	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
DMNEPPOG_01503	8.59e-149	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
DMNEPPOG_01504	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
DMNEPPOG_01505	9.44e-190	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
DMNEPPOG_01506	1.34e-126	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
DMNEPPOG_01507	1e-271	-	-	-	M	-	-	-	Glycosyl transferases group 1
DMNEPPOG_01508	0.0	yebA	-	-	E	-	-	-	Transglutaminase/protease-like homologues
DMNEPPOG_01509	5.5e-238	-	-	-	S	-	-	-	Protein of unknown function DUF58
DMNEPPOG_01510	1.49e-181	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
DMNEPPOG_01511	7.75e-138	-	-	-	S	ko:K06384	-	ko00000	Stage II sporulation protein M
DMNEPPOG_01512	9.37e-129	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
DMNEPPOG_01513	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DMNEPPOG_01514	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DMNEPPOG_01515	1.09e-170	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DMNEPPOG_01516	1.66e-216	-	-	-	G	-	-	-	Phosphotransferase enzyme family
DMNEPPOG_01517	7.76e-186	-	-	-	S	-	-	-	AAA ATPase domain
DMNEPPOG_01518	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
DMNEPPOG_01519	6.11e-106	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
DMNEPPOG_01520	1.4e-69	-	-	-	-	-	-	-	-
DMNEPPOG_01521	9.87e-52	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
DMNEPPOG_01522	1.33e-166	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
DMNEPPOG_01523	2.97e-305	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
DMNEPPOG_01524	4.51e-41	-	-	-	-	-	-	-	-
DMNEPPOG_01525	6.58e-173	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DMNEPPOG_01526	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DMNEPPOG_01528	6.17e-204	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
DMNEPPOG_01529	8.33e-193	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DMNEPPOG_01530	1.31e-245	-	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
DMNEPPOG_01531	9.77e-279	-	-	-	EGP	-	-	-	Major facilitator Superfamily
DMNEPPOG_01532	1.44e-230	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
DMNEPPOG_01533	1.57e-171	manM	-	-	G	ko:K02746,ko:K02795,ko:K02814	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
DMNEPPOG_01534	1.73e-216	manN	-	-	G	ko:K02796,ko:K02815	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
DMNEPPOG_01535	1.08e-84	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
DMNEPPOG_01536	2.11e-220	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
DMNEPPOG_01537	2.07e-239	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
DMNEPPOG_01540	2.25e-285	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DMNEPPOG_01542	2.14e-24	-	-	-	-	-	-	-	-
DMNEPPOG_01543	1.81e-221	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
DMNEPPOG_01544	9.57e-207	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
DMNEPPOG_01545	3.63e-216	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DMNEPPOG_01546	2.21e-275	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
DMNEPPOG_01547	8.84e-211	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DMNEPPOG_01548	1.26e-180	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
DMNEPPOG_01549	7.4e-203	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
DMNEPPOG_01550	8.19e-212	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
DMNEPPOG_01551	5.77e-118	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
DMNEPPOG_01552	0.0	ycaM	-	-	E	-	-	-	amino acid
DMNEPPOG_01553	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
DMNEPPOG_01554	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
DMNEPPOG_01555	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
DMNEPPOG_01556	3.56e-121	-	-	-	-	-	-	-	-
DMNEPPOG_01557	1.32e-269	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
DMNEPPOG_01558	4.81e-181	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
DMNEPPOG_01559	3.6e-253	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
DMNEPPOG_01560	1.9e-164	-	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
DMNEPPOG_01561	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
DMNEPPOG_01562	7.08e-166	XK27_12140	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
DMNEPPOG_01563	3.16e-258	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
DMNEPPOG_01564	1.25e-236	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
DMNEPPOG_01565	8.63e-164	-	-	-	M	-	-	-	domain protein
DMNEPPOG_01566	0.0	yvcC	-	-	M	-	-	-	Cna protein B-type domain
DMNEPPOG_01567	7.58e-134	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
DMNEPPOG_01568	0.0	-	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
DMNEPPOG_01569	4.8e-66	licB2	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DMNEPPOG_01570	3.96e-293	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DMNEPPOG_01571	1.54e-75	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
DMNEPPOG_01572	0.0	-	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DMNEPPOG_01573	1.68e-124	-	-	-	-	-	-	-	-
DMNEPPOG_01574	2.92e-68	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
DMNEPPOG_01575	1.5e-256	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
DMNEPPOG_01576	9.58e-211	-	-	-	S	-	-	-	reductase
DMNEPPOG_01577	1.68e-98	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
DMNEPPOG_01578	0.0	-	-	-	E	-	-	-	Amino acid permease
DMNEPPOG_01579	2.51e-284	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
DMNEPPOG_01580	0.0	-	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamine synthetase, catalytic domain
DMNEPPOG_01581	1.15e-183	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
DMNEPPOG_01582	2.6e-185	-	-	-	H	-	-	-	Protein of unknown function (DUF1698)
DMNEPPOG_01583	4.08e-248	pbpE	-	-	V	-	-	-	Beta-lactamase
DMNEPPOG_01585	0.0	cidC	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
DMNEPPOG_01586	5.36e-215	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
DMNEPPOG_01587	6.8e-140	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
DMNEPPOG_01588	2.07e-140	ydfF	-	-	K	-	-	-	Transcriptional
DMNEPPOG_01589	4.02e-262	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
DMNEPPOG_01590	5.14e-65	yczG	-	-	K	-	-	-	Helix-turn-helix domain
DMNEPPOG_01591	0.0	-	-	-	L	-	-	-	Exonuclease
DMNEPPOG_01592	1.05e-101	-	-	-	O	-	-	-	OsmC-like protein
DMNEPPOG_01593	1.03e-242	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
DMNEPPOG_01594	4.95e-134	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
DMNEPPOG_01595	2.1e-78	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
DMNEPPOG_01596	2.11e-132	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DMNEPPOG_01597	7.24e-23	-	-	-	-	-	-	-	-
DMNEPPOG_01598	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
DMNEPPOG_01599	4.99e-105	-	-	-	-	-	-	-	-
DMNEPPOG_01600	5.84e-253	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
DMNEPPOG_01601	1.91e-201	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
DMNEPPOG_01602	1.64e-204	pip	-	-	V	ko:K01421	-	ko00000	domain protein
DMNEPPOG_01603	2.31e-293	pip	-	-	V	ko:K01421	-	ko00000	domain protein
DMNEPPOG_01605	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
DMNEPPOG_01606	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
DMNEPPOG_01607	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
DMNEPPOG_01608	1.51e-90	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
DMNEPPOG_01609	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
DMNEPPOG_01610	7.9e-196	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
DMNEPPOG_01611	2.18e-177	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
DMNEPPOG_01612	1.48e-109	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
DMNEPPOG_01613	1.15e-237	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
DMNEPPOG_01614	1.81e-59	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
DMNEPPOG_01615	2.97e-49	-	-	-	T	-	-	-	Calcineurin-like phosphoesterase superfamily domain
DMNEPPOG_01616	0.0	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
DMNEPPOG_01618	4.68e-53	-	-	-	-	-	-	-	-
DMNEPPOG_01619	2.66e-57	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
DMNEPPOG_01620	1.4e-238	yveB	-	-	I	-	-	-	PAP2 superfamily
DMNEPPOG_01621	2.35e-269	mccF	-	-	V	-	-	-	LD-carboxypeptidase
DMNEPPOG_01622	6.55e-57	-	-	-	-	-	-	-	-
DMNEPPOG_01623	2.61e-261	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
DMNEPPOG_01624	2.88e-116	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
DMNEPPOG_01625	1.17e-245	ldhD3	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DMNEPPOG_01626	1.21e-59	-	-	-	-	-	-	-	-
DMNEPPOG_01627	2.74e-112	-	-	-	K	-	-	-	Transcriptional regulator
DMNEPPOG_01628	1.07e-239	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	alcohol dehydrogenase
DMNEPPOG_01629	1.61e-72	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
DMNEPPOG_01630	2.42e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
DMNEPPOG_01631	0.0	XK27_07275	-	-	S	ko:K06901	-	ko00000,ko02000	permease
DMNEPPOG_01632	1.2e-61	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
DMNEPPOG_01633	3.38e-227	mhqA	-	-	E	ko:K15975	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DMNEPPOG_01634	6.64e-39	-	-	-	-	-	-	-	-
DMNEPPOG_01635	1.8e-135	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DMNEPPOG_01636	0.0	-	-	-	-	-	-	-	-
DMNEPPOG_01638	3.46e-168	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
DMNEPPOG_01639	5.01e-172	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
DMNEPPOG_01640	3.52e-245	ynjC	-	-	S	-	-	-	Cell surface protein
DMNEPPOG_01642	0.0	-	-	-	L	-	-	-	Mga helix-turn-helix domain
DMNEPPOG_01643	5.89e-232	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
DMNEPPOG_01644	1.1e-76	-	-	-	-	-	-	-	-
DMNEPPOG_01645	0.0	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
DMNEPPOG_01646	5.29e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DMNEPPOG_01647	2.01e-205	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
DMNEPPOG_01648	8.09e-180	-	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
DMNEPPOG_01649	8.86e-62	-	-	-	S	-	-	-	Thiamine-binding protein
DMNEPPOG_01650	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
DMNEPPOG_01651	4.77e-130	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DMNEPPOG_01652	0.0	bmr3	-	-	EGP	-	-	-	Major Facilitator
DMNEPPOG_01654	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
DMNEPPOG_01655	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
DMNEPPOG_01656	1.15e-25	-	-	-	-	-	-	-	-
DMNEPPOG_01658	8.72e-105	-	-	-	S	-	-	-	NUDIX domain
DMNEPPOG_01659	1.33e-276	-	-	-	S	-	-	-	nuclear-transcribed mRNA catabolic process, no-go decay
DMNEPPOG_01660	0.0	fnq20	-	-	S	-	-	-	FAD-NAD(P)-binding
DMNEPPOG_01661	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
DMNEPPOG_01662	1.03e-148	-	-	-	-	-	-	-	-
DMNEPPOG_01663	2.18e-289	-	-	-	S	ko:K06872	-	ko00000	TPM domain
DMNEPPOG_01664	5.06e-177	yunE	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
DMNEPPOG_01665	6.45e-74	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
DMNEPPOG_01666	1.47e-07	-	-	-	-	-	-	-	-
DMNEPPOG_01667	5.12e-117	-	-	-	-	-	-	-	-
DMNEPPOG_01668	4.85e-65	-	-	-	-	-	-	-	-
DMNEPPOG_01669	1.63e-109	-	-	-	C	-	-	-	Flavodoxin
DMNEPPOG_01670	5.54e-50	-	-	-	-	-	-	-	-
DMNEPPOG_01671	2.82e-36	-	-	-	-	-	-	-	-
DMNEPPOG_01672	2.86e-219	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DMNEPPOG_01673	2.27e-94	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
DMNEPPOG_01674	4.95e-53	-	-	-	S	-	-	-	Transglycosylase associated protein
DMNEPPOG_01675	5.77e-113	-	-	-	S	-	-	-	Protein conserved in bacteria
DMNEPPOG_01676	4.15e-34	-	-	-	-	-	-	-	-
DMNEPPOG_01677	1.35e-88	asp23	-	-	S	-	-	-	Asp23 family, cell envelope-related function
DMNEPPOG_01678	1.97e-92	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
DMNEPPOG_01679	9.28e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
DMNEPPOG_01680	9.56e-194	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
DMNEPPOG_01681	6.93e-154	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DMNEPPOG_01682	3.05e-139	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
DMNEPPOG_01683	6.67e-165	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
DMNEPPOG_01684	4.01e-87	-	-	-	-	-	-	-	-
DMNEPPOG_01685	3.36e-169	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
DMNEPPOG_01686	6.84e-189	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
DMNEPPOG_01687	1.49e-177	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
DMNEPPOG_01688	1.11e-201	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
DMNEPPOG_01689	3.26e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
DMNEPPOG_01690	9.76e-237	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
DMNEPPOG_01691	7.77e-173	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
DMNEPPOG_01692	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DMNEPPOG_01693	1.23e-157	-	-	-	-	-	-	-	-
DMNEPPOG_01694	1.68e-156	vanR	-	-	K	-	-	-	response regulator
DMNEPPOG_01695	2.81e-278	hpk31	-	-	T	-	-	-	Histidine kinase
DMNEPPOG_01696	2.75e-303	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
DMNEPPOG_01697	1.02e-103	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DMNEPPOG_01698	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DMNEPPOG_01699	2.71e-182	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
DMNEPPOG_01700	2.35e-210	yvgN	-	-	C	-	-	-	Aldo keto reductase
DMNEPPOG_01701	3.54e-187	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
DMNEPPOG_01702	0.0	iolT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
DMNEPPOG_01703	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
DMNEPPOG_01704	8.47e-201	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
DMNEPPOG_01705	6.58e-228	iolC	2.7.1.92	-	H	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
DMNEPPOG_01706	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
DMNEPPOG_01707	9.62e-247	-	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
DMNEPPOG_01708	3.37e-249	iolG2	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
DMNEPPOG_01709	1.99e-21	licR	-	-	G	ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DMNEPPOG_01710	3.46e-207	-	-	-	G	-	-	-	Fructose-bisphosphate aldolase class-II
DMNEPPOG_01711	0.0	-	-	-	G	-	-	-	FGGY family of carbohydrate kinases, C-terminal domain
DMNEPPOG_01712	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
DMNEPPOG_01713	9.89e-64	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DMNEPPOG_01714	7.61e-102	-	2.7.1.200	-	GT	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DMNEPPOG_01715	2.63e-206	-	-	-	G	-	-	-	Fructose-bisphosphate aldolase class-II
DMNEPPOG_01716	1.97e-173	farR	-	-	K	-	-	-	Helix-turn-helix domain
DMNEPPOG_01717	1.66e-116	-	-	-	M	ko:K03828	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
DMNEPPOG_01718	2.16e-132	laaE	-	-	K	-	-	-	Transcriptional regulator PadR-like family
DMNEPPOG_01719	0.0	chaT1	-	-	U	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
DMNEPPOG_01720	2.75e-116	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DMNEPPOG_01721	3.62e-121	yveA	-	-	Q	-	-	-	Isochorismatase family
DMNEPPOG_01722	9.53e-76	ps105	-	-	-	-	-	-	-
DMNEPPOG_01724	5.38e-125	-	-	-	K	-	-	-	Helix-turn-helix domain
DMNEPPOG_01725	3.79e-155	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
DMNEPPOG_01726	3.87e-97	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DMNEPPOG_01727	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
DMNEPPOG_01728	2.92e-192	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DMNEPPOG_01729	3.19e-211	-	-	-	P	ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type sugar transport systems, permease components
DMNEPPOG_01730	7.33e-271	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
DMNEPPOG_01731	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DMNEPPOG_01732	1.89e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
DMNEPPOG_01733	3.28e-175	-	-	-	F	-	-	-	NUDIX domain
DMNEPPOG_01734	1.45e-187	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
DMNEPPOG_01735	9.61e-247	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
DMNEPPOG_01736	1.13e-251	-	-	-	V	-	-	-	Beta-lactamase
DMNEPPOG_01737	1.43e-197	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DMNEPPOG_01738	1.58e-211	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
DMNEPPOG_01739	1.67e-105	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
DMNEPPOG_01740	1.56e-192	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
DMNEPPOG_01741	8.76e-177	XK27_08455	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
DMNEPPOG_01742	1.76e-258	-	-	-	S	-	-	-	endonuclease exonuclease phosphatase family protein
DMNEPPOG_01743	2.28e-220	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
DMNEPPOG_01744	1.18e-134	-	-	-	Q	-	-	-	Methyltransferase
DMNEPPOG_01745	2.16e-68	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
DMNEPPOG_01746	2.69e-22	-	-	-	-	-	-	-	-
DMNEPPOG_01747	2.45e-59	-	-	-	I	-	-	-	carboxylic ester hydrolase activity
DMNEPPOG_01748	3.22e-65	-	-	-	S	-	-	-	alpha beta
DMNEPPOG_01749	3.81e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
DMNEPPOG_01750	5.44e-174	-	-	-	S	-	-	-	-acetyltransferase
DMNEPPOG_01751	7.49e-85	yfbM	-	-	K	-	-	-	FR47-like protein
DMNEPPOG_01752	2.42e-122	-	-	-	E	-	-	-	HAD-hyrolase-like
DMNEPPOG_01753	4.93e-244	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
DMNEPPOG_01754	8.05e-180	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
DMNEPPOG_01755	1.7e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DMNEPPOG_01756	5.73e-110	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
DMNEPPOG_01757	1.07e-104	-	-	-	K	ko:K03830	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
DMNEPPOG_01758	2.08e-301	-	-	-	K	-	-	-	Putative DNA-binding domain
DMNEPPOG_01759	1.06e-163	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
DMNEPPOG_01762	1.01e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DMNEPPOG_01763	8.97e-253	ysdE	-	-	P	-	-	-	Citrate transporter
DMNEPPOG_01764	8.69e-91	-	-	-	-	-	-	-	-
DMNEPPOG_01765	0.0	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
DMNEPPOG_01766	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
DMNEPPOG_01767	2.96e-134	-	-	-	-	-	-	-	-
DMNEPPOG_01768	0.0	cadA	-	-	P	-	-	-	P-type ATPase
DMNEPPOG_01769	2.56e-99	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
DMNEPPOG_01770	2.35e-92	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
DMNEPPOG_01771	3.43e-284	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
DMNEPPOG_01773	4.32e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
DMNEPPOG_01774	1.05e-182	yycI	-	-	S	-	-	-	YycH protein
DMNEPPOG_01775	0.0	yycH	-	-	S	-	-	-	YycH protein
DMNEPPOG_01776	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
DMNEPPOG_01777	3.03e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
DMNEPPOG_01778	1.24e-156	-	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Alpha/beta hydrolase family
DMNEPPOG_01779	0.0	arpJ	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
DMNEPPOG_01780	1.39e-299	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
DMNEPPOG_01781	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
DMNEPPOG_01782	4.78e-273	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
DMNEPPOG_01783	9.09e-97	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
DMNEPPOG_01784	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DMNEPPOG_01785	1.97e-168	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
DMNEPPOG_01786	5.01e-69	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DMNEPPOG_01787	8.36e-72	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
DMNEPPOG_01788	1.82e-140	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
DMNEPPOG_01789	1.84e-110	-	-	-	F	-	-	-	NUDIX domain
DMNEPPOG_01790	1.35e-119	-	-	-	S	-	-	-	AAA domain
DMNEPPOG_01791	3.32e-148	ycaC	-	-	Q	-	-	-	Isochorismatase family
DMNEPPOG_01792	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
DMNEPPOG_01793	4.46e-16	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
DMNEPPOG_01794	1.33e-211	XK27_08510	-	-	L	-	-	-	Type III restriction protein res subunit
DMNEPPOG_01795	3.78e-41	XK27_08510	-	-	L	-	-	-	Type III restriction protein res subunit
DMNEPPOG_01797	1.87e-31	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
DMNEPPOG_01799	1.45e-55	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
DMNEPPOG_01801	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
DMNEPPOG_01802	1.27e-144	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
DMNEPPOG_01803	1.46e-148	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
DMNEPPOG_01804	4.11e-83	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
DMNEPPOG_01805	2.11e-38	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
DMNEPPOG_01806	1.39e-91	xylR	-	-	GK	-	-	-	ROK family
DMNEPPOG_01807	7.52e-151	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
DMNEPPOG_01808	2.54e-20	-	-	-	L	-	-	-	Transposase DDE domain
DMNEPPOG_01809	1.69e-10	-	-	-	-	-	-	-	-
DMNEPPOG_01810	3.35e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
DMNEPPOG_01811	8.39e-21	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
DMNEPPOG_01812	2.93e-234	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
DMNEPPOG_01813	4.68e-189	-	-	-	-	-	-	-	-
DMNEPPOG_01814	1.38e-274	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
DMNEPPOG_01815	6.84e-186	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
DMNEPPOG_01816	8.58e-159	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DMNEPPOG_01817	3.19e-42	-	-	-	-	-	-	-	-
DMNEPPOG_01818	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
DMNEPPOG_01819	4.64e-151	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
DMNEPPOG_01820	2.1e-226	-	-	-	S	-	-	-	Cell surface protein
DMNEPPOG_01821	1.78e-58	-	-	-	-	-	-	-	-
DMNEPPOG_01822	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
DMNEPPOG_01823	1.66e-154	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
DMNEPPOG_01824	4.82e-78	-	-	-	-	-	-	-	-
DMNEPPOG_01825	3.82e-142	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
DMNEPPOG_01826	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
DMNEPPOG_01827	1.99e-224	yicL	-	-	EG	-	-	-	EamA-like transporter family
DMNEPPOG_01828	0.0	-	-	-	-	-	-	-	-
DMNEPPOG_01829	3.03e-186	CcmA5	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
DMNEPPOG_01830	4.07e-114	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
DMNEPPOG_01831	2.6e-192	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
DMNEPPOG_01832	7.88e-211	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
DMNEPPOG_01833	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DMNEPPOG_01834	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
DMNEPPOG_01835	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DMNEPPOG_01836	3.34e-286	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
DMNEPPOG_01837	5.43e-167	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
DMNEPPOG_01838	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
DMNEPPOG_01839	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
DMNEPPOG_01840	1.51e-283	sstT	-	-	U	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
DMNEPPOG_01841	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
DMNEPPOG_01842	3.94e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
DMNEPPOG_01843	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
DMNEPPOG_01844	3.08e-43	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
DMNEPPOG_01845	1.54e-91	-	-	-	-	-	-	-	-
DMNEPPOG_01846	3.93e-99	-	-	-	O	-	-	-	OsmC-like protein
DMNEPPOG_01847	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
DMNEPPOG_01848	2.73e-147	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
DMNEPPOG_01850	4.04e-204	-	-	-	S	-	-	-	Aldo/keto reductase family
DMNEPPOG_01851	9.04e-317	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
DMNEPPOG_01852	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF3800)
DMNEPPOG_01853	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
DMNEPPOG_01854	2.72e-78	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
DMNEPPOG_01855	1.2e-95	-	-	-	K	-	-	-	LytTr DNA-binding domain
DMNEPPOG_01856	3.12e-191	-	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
DMNEPPOG_01857	6.73e-211	-	-	-	V	ko:K01990,ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DMNEPPOG_01858	1.51e-188	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
DMNEPPOG_01859	1.11e-105	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
DMNEPPOG_01860	1.9e-40	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
DMNEPPOG_01861	1.06e-69	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
DMNEPPOG_01862	4.51e-207	-	-	-	C	-	-	-	nadph quinone reductase
DMNEPPOG_01863	3.8e-316	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
DMNEPPOG_01864	7.13e-106	-	-	-	I	-	-	-	ABC-2 family transporter protein
DMNEPPOG_01865	9.19e-209	CcmA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
DMNEPPOG_01866	6.81e-86	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
DMNEPPOG_01867	1.9e-279	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
DMNEPPOG_01868	3.08e-113	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
DMNEPPOG_01869	6.31e-84	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
DMNEPPOG_01870	1.92e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DMNEPPOG_01871	3.26e-226	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
DMNEPPOG_01872	2.92e-204	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
DMNEPPOG_01873	2.21e-258	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
DMNEPPOG_01874	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
DMNEPPOG_01875	7.45e-90	-	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
DMNEPPOG_01876	1.28e-163	WQ51_05710	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
DMNEPPOG_01877	2.63e-60	-	-	-	-	-	-	-	-
DMNEPPOG_01879	3.99e-278	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
DMNEPPOG_01880	4.61e-222	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DMNEPPOG_01881	1.44e-220	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
DMNEPPOG_01882	5.38e-51	-	-	-	-	-	-	-	-
DMNEPPOG_01883	3.56e-274	floL	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	SPFH domain / Band 7 family
DMNEPPOG_01884	9.28e-317	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
DMNEPPOG_01885	6.52e-290	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
DMNEPPOG_01886	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
DMNEPPOG_01887	1.18e-190	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
DMNEPPOG_01888	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
DMNEPPOG_01889	2.6e-96	usp1	-	-	T	-	-	-	Universal stress protein family
DMNEPPOG_01890	2.81e-176	sfsA	-	-	S	ko:K06206	-	ko00000	Belongs to the SfsA family
DMNEPPOG_01891	3.74e-284	gbuA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
DMNEPPOG_01892	5.82e-189	gbuB	-	-	E	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
DMNEPPOG_01893	8.26e-215	gbuC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
DMNEPPOG_01894	0.0	-	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
DMNEPPOG_01895	7.3e-217	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
DMNEPPOG_01896	1.41e-85	gtcA2	-	-	S	-	-	-	Teichoic acid glycosylation protein
DMNEPPOG_01897	4.31e-166	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
DMNEPPOG_01898	9.44e-239	ydbI	-	-	K	-	-	-	AI-2E family transporter
DMNEPPOG_01899	4.87e-261	pbpX	-	-	V	-	-	-	Beta-lactamase
DMNEPPOG_01900	1.7e-193	-	-	-	S	-	-	-	zinc-ribbon domain
DMNEPPOG_01901	4.74e-30	-	-	-	-	-	-	-	-
DMNEPPOG_01902	1.91e-167	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DMNEPPOG_01903	1.56e-104	-	-	-	F	-	-	-	NUDIX domain
DMNEPPOG_01904	7.44e-282	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
DMNEPPOG_01905	3.75e-102	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
DMNEPPOG_01906	1.47e-136	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
DMNEPPOG_01907	5.23e-256	-	-	-	-	-	-	-	-
DMNEPPOG_01908	5.89e-215	-	-	-	S	-	-	-	Putative esterase
DMNEPPOG_01909	2.29e-14	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
DMNEPPOG_01910	9.13e-85	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	MarR family
DMNEPPOG_01911	5.73e-63	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
DMNEPPOG_01912	4.27e-78	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
DMNEPPOG_01913	3.43e-61	-	-	-	P	-	-	-	Rhodanese-like domain
DMNEPPOG_01915	1.08e-287	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
DMNEPPOG_01916	9.95e-244	-	-	-	E	-	-	-	Alpha/beta hydrolase family
DMNEPPOG_01918	6.79e-95	-	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
DMNEPPOG_01919	2.44e-99	-	-	-	K	-	-	-	Winged helix DNA-binding domain
DMNEPPOG_01920	3.96e-226	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DMNEPPOG_01921	2.78e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DMNEPPOG_01922	4.56e-220	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
DMNEPPOG_01923	8.45e-210	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
DMNEPPOG_01924	8.26e-164	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
DMNEPPOG_01925	6.98e-284	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
DMNEPPOG_01926	8.8e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
DMNEPPOG_01927	3.23e-98	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
DMNEPPOG_01928	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
DMNEPPOG_01929	5.9e-192	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DMNEPPOG_01930	3.41e-184	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
DMNEPPOG_01931	3.95e-297	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
DMNEPPOG_01932	9.54e-208	-	-	-	GM	-	-	-	NmrA-like family
DMNEPPOG_01933	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
DMNEPPOG_01934	3.69e-233	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
DMNEPPOG_01935	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
DMNEPPOG_01936	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
DMNEPPOG_01937	4.08e-270	-	-	-	-	-	-	-	-
DMNEPPOG_01938	4.41e-10	-	-	-	-	-	-	-	-
DMNEPPOG_01939	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
DMNEPPOG_01940	1.53e-241	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DMNEPPOG_01941	1.03e-208	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DMNEPPOG_01942	1.52e-208	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
DMNEPPOG_01943	2.09e-215	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
DMNEPPOG_01944	3.93e-15	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
DMNEPPOG_01945	1.18e-250	-	-	-	S	-	-	-	Protein of unknown function C-terminal (DUF3324)
DMNEPPOG_01946	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
DMNEPPOG_01947	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DMNEPPOG_01948	1.14e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
DMNEPPOG_01949	1.55e-309	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
DMNEPPOG_01950	1.17e-105	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
DMNEPPOG_01951	3.35e-87	divIC	-	-	D	ko:K05589,ko:K13052	-	ko00000,ko03036	cell cycle
DMNEPPOG_01952	1.99e-53	yabO	-	-	J	-	-	-	S4 domain protein
DMNEPPOG_01953	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
DMNEPPOG_01954	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DMNEPPOG_01955	4.28e-131	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
DMNEPPOG_01956	5.04e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
DMNEPPOG_01957	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
DMNEPPOG_01958	4.14e-126	padR	-	-	K	-	-	-	Transcriptional regulator PadR-like family
DMNEPPOG_01959	0.0	-	-	-	S	ko:K01421	-	ko00000	ABC-2 family transporter protein
DMNEPPOG_01960	2.45e-150	-	-	-	S	-	-	-	Flavodoxin-like fold
DMNEPPOG_01961	1.34e-154	-	-	-	S	-	-	-	(CBS) domain
DMNEPPOG_01962	4.2e-75	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
DMNEPPOG_01963	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
DMNEPPOG_01964	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
DMNEPPOG_01965	1.39e-112	queT	-	-	S	-	-	-	QueT transporter
DMNEPPOG_01966	5.68e-83	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
DMNEPPOG_01967	4.66e-44	-	-	-	-	-	-	-	-
DMNEPPOG_01968	1.14e-277	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DMNEPPOG_01969	2.63e-82	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
DMNEPPOG_01970	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
DMNEPPOG_01971	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
DMNEPPOG_01972	1.7e-187	-	-	-	-	-	-	-	-
DMNEPPOG_01973	3.18e-161	-	-	-	S	-	-	-	Tetratricopeptide repeat
DMNEPPOG_01974	2.61e-163	-	-	-	-	-	-	-	-
DMNEPPOG_01975	2.29e-87	-	-	-	-	-	-	-	-
DMNEPPOG_01976	0.0	-	-	-	M	-	-	-	domain protein
DMNEPPOG_01978	1.99e-69	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF961)
DMNEPPOG_01979	2.86e-81	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF961)
DMNEPPOG_01984	1.33e-98	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
DMNEPPOG_01985	8.82e-217	-	-	-	D	-	-	-	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
DMNEPPOG_01991	2.67e-92	-	-	-	-	-	-	-	-
DMNEPPOG_01992	4.03e-276	-	-	-	K	ko:K07467	-	ko00000	Replication initiation factor
DMNEPPOG_01993	6.4e-72	-	-	-	-	-	-	-	-
DMNEPPOG_01994	1.53e-106	-	-	-	L	-	-	-	DNA methylase
DMNEPPOG_01995	1.84e-41	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
DMNEPPOG_01996	1.94e-115	-	-	-	S	-	-	-	Antirestriction protein (ArdA)
DMNEPPOG_01997	1.4e-90	-	-	-	S	-	-	-	TcpE family
DMNEPPOG_01998	0.0	-	-	-	S	-	-	-	AAA-like domain
DMNEPPOG_01999	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
DMNEPPOG_02000	7.55e-241	yddH	-	-	M	-	-	-	NlpC/P60 family
DMNEPPOG_02001	8.49e-52	-	-	-	-	-	-	-	-
DMNEPPOG_02002	2.64e-213	-	-	-	S	-	-	-	Conjugative transposon protein TcpC
DMNEPPOG_02003	2.25e-134	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
DMNEPPOG_02004	1.74e-177	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DMNEPPOG_02005	2.46e-174	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DMNEPPOG_02006	1.97e-188	ptxC	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DMNEPPOG_02007	6.58e-227	ssuA	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	NMT1-like family
DMNEPPOG_02008	0.0	-	6.2.1.48	-	IQ	ko:K02182	-	ko00000,ko01000	AMP-binding enzyme C-terminal domain
DMNEPPOG_02009	1.2e-302	-	-	-	I	-	-	-	Acyltransferase family
DMNEPPOG_02010	2.03e-155	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
DMNEPPOG_02011	1.02e-192	ssuC	-	-	U	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DMNEPPOG_02012	7.94e-175	XK27_06950	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
DMNEPPOG_02013	1.81e-174	XK27_06945	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
DMNEPPOG_02014	3.3e-174	-	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
DMNEPPOG_02015	1.17e-123	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
DMNEPPOG_02016	1.28e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
DMNEPPOG_02017	9.26e-146	-	-	-	-	-	-	-	-
DMNEPPOG_02018	1.29e-74	-	-	-	-	-	-	-	-
DMNEPPOG_02019	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
DMNEPPOG_02020	2.98e-104	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DMNEPPOG_02021	1.46e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DMNEPPOG_02022	1.06e-237	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
DMNEPPOG_02023	4.46e-165	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
DMNEPPOG_02024	1.5e-44	-	-	-	-	-	-	-	-
DMNEPPOG_02025	3.24e-171	tipA	-	-	K	-	-	-	TipAS antibiotic-recognition domain
DMNEPPOG_02026	1.39e-178	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
DMNEPPOG_02027	1.13e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DMNEPPOG_02028	1.92e-202	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DMNEPPOG_02029	1.15e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DMNEPPOG_02030	9.02e-154	-	-	-	-	-	-	-	-
DMNEPPOG_02031	7.28e-15	-	-	-	-	-	-	-	-
DMNEPPOG_02032	5.46e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
DMNEPPOG_02033	1.26e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DMNEPPOG_02034	3.82e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DMNEPPOG_02035	5.37e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DMNEPPOG_02036	6.38e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
DMNEPPOG_02037	4.15e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DMNEPPOG_02038	1.11e-156	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
DMNEPPOG_02039	1.16e-302	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
DMNEPPOG_02040	4.07e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
DMNEPPOG_02041	2.6e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
DMNEPPOG_02042	5.74e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DMNEPPOG_02043	1.62e-76	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DMNEPPOG_02044	2.61e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DMNEPPOG_02045	1.32e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DMNEPPOG_02046	8.67e-124	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DMNEPPOG_02047	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DMNEPPOG_02048	1.73e-77	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DMNEPPOG_02049	5.93e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DMNEPPOG_02050	3.55e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
DMNEPPOG_02051	1.38e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DMNEPPOG_02052	6.88e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DMNEPPOG_02053	4.5e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DMNEPPOG_02054	5.26e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DMNEPPOG_02055	7.23e-201	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DMNEPPOG_02056	1.02e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
DMNEPPOG_02057	1.98e-140	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
DMNEPPOG_02058	4.01e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DMNEPPOG_02059	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
DMNEPPOG_02060	3.63e-90	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
DMNEPPOG_02061	2.38e-138	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
DMNEPPOG_02062	3.54e-257	-	-	-	K	-	-	-	WYL domain
DMNEPPOG_02063	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DMNEPPOG_02064	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
DMNEPPOG_02065	1.11e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DMNEPPOG_02066	0.0	-	-	-	M	-	-	-	domain protein
DMNEPPOG_02067	1.47e-46	-	3.4.23.43	-	-	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	-
DMNEPPOG_02068	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DMNEPPOG_02069	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DMNEPPOG_02070	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
DMNEPPOG_02071	4.32e-105	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
DMNEPPOG_02080	7.4e-264	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
DMNEPPOG_02081	4.2e-188	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
DMNEPPOG_02082	6.97e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
DMNEPPOG_02083	3.33e-211	-	-	-	P	-	-	-	CorA-like Mg2+ transporter protein
DMNEPPOG_02084	3.29e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DMNEPPOG_02086	2.37e-306	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
DMNEPPOG_02088	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
DMNEPPOG_02089	1.02e-144	-	-	-	S	-	-	-	Membrane
DMNEPPOG_02090	4.98e-68	-	-	-	-	-	-	-	-
DMNEPPOG_02091	4.32e-133	-	-	-	-	-	-	-	-
DMNEPPOG_02092	2.3e-101	-	-	-	-	-	-	-	-
DMNEPPOG_02093	4.97e-70	-	-	-	-	-	-	-	-
DMNEPPOG_02094	1.95e-159	azlC	-	-	E	-	-	-	branched-chain amino acid
DMNEPPOG_02095	1.83e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
DMNEPPOG_02097	2.44e-40	-	-	-	-	-	-	-	-
DMNEPPOG_02098	2.25e-185	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DMNEPPOG_02099	6.9e-150	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
DMNEPPOG_02100	4.48e-162	kdgR	-	-	K	-	-	-	FCD domain
DMNEPPOG_02101	3.45e-74	ps105	-	-	-	-	-	-	-
DMNEPPOG_02102	3.38e-210	-	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
DMNEPPOG_02103	2.92e-178	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
DMNEPPOG_02104	4.88e-151	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
DMNEPPOG_02105	1.64e-247	-	-	-	EGP	-	-	-	Major Facilitator
DMNEPPOG_02106	2.9e-40	-	-	-	EGP	-	-	-	Major Facilitator
DMNEPPOG_02108	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
DMNEPPOG_02109	2.34e-140	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
DMNEPPOG_02111	3.93e-142	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DMNEPPOG_02112	3.55e-222	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
DMNEPPOG_02113	2.28e-136	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DMNEPPOG_02114	8.51e-286	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
DMNEPPOG_02115	0.000666	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DMNEPPOG_02117	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
DMNEPPOG_02118	3.61e-46	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
DMNEPPOG_02119	3.09e-133	dpsB	-	-	P	-	-	-	Belongs to the Dps family
DMNEPPOG_02120	2.13e-150	flp	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
DMNEPPOG_02121	2.39e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
DMNEPPOG_02122	5e-293	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DMNEPPOG_02123	6.7e-135	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
DMNEPPOG_02124	7.66e-178	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
DMNEPPOG_02125	8.74e-236	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DMNEPPOG_02126	1.02e-298	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
DMNEPPOG_02127	1.47e-60	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DMNEPPOG_02128	8.8e-103	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DMNEPPOG_02129	2.51e-176	-	-	-	S	-	-	-	Domain of unknown function (DUF4918)
DMNEPPOG_02130	3.34e-268	-	-	-	-	-	-	-	-
DMNEPPOG_02131	0.0	-	-	-	EGP	-	-	-	Major Facilitator
DMNEPPOG_02132	1.04e-139	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DMNEPPOG_02134	3.66e-166	-	-	-	-	-	-	-	-
DMNEPPOG_02135	2.19e-289	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type transport system involved in multi-copper enzyme maturation permease component
DMNEPPOG_02136	1.64e-210	-	-	-	-	-	-	-	-
DMNEPPOG_02137	1.38e-155	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
DMNEPPOG_02138	7.63e-85	-	-	-	S	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
DMNEPPOG_02140	7.65e-61	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
DMNEPPOG_02141	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
DMNEPPOG_02143	2.3e-23	-	-	-	-	-	-	-	-
DMNEPPOG_02144	1.4e-35	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
DMNEPPOG_02145	1.26e-52	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
DMNEPPOG_02147	6.55e-93	-	-	-	S	-	-	-	SdpI/YhfL protein family
DMNEPPOG_02148	3.55e-174	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
DMNEPPOG_02149	0.0	yclK	-	-	T	-	-	-	Histidine kinase
DMNEPPOG_02150	3.29e-97	-	-	-	S	-	-	-	acetyltransferase
DMNEPPOG_02151	1.16e-19	-	-	-	-	-	-	-	-
DMNEPPOG_02152	1.27e-94	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
DMNEPPOG_02153	1.53e-88	-	-	-	-	-	-	-	-
DMNEPPOG_02154	4.96e-73	-	-	-	-	-	-	-	-
DMNEPPOG_02155	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
DMNEPPOG_02157	3.92e-270	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
DMNEPPOG_02158	7.4e-182	-	3.1.1.5	-	E	ko:K10804	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	GDSL-like Lipase/Acylhydrolase
DMNEPPOG_02159	5.65e-46	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
DMNEPPOG_02161	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
DMNEPPOG_02162	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DMNEPPOG_02163	3e-271	camS	-	-	S	-	-	-	sex pheromone
DMNEPPOG_02164	3.61e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DMNEPPOG_02165	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
DMNEPPOG_02166	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DMNEPPOG_02167	4.97e-248	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
DMNEPPOG_02168	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DMNEPPOG_02169	2.17e-279	yttB	-	-	EGP	-	-	-	Major Facilitator
DMNEPPOG_02170	6.2e-191	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
DMNEPPOG_02171	8.52e-211	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
DMNEPPOG_02172	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
DMNEPPOG_02173	0.0	-	-	-	EGP	-	-	-	Major Facilitator
DMNEPPOG_02174	4.37e-107	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
DMNEPPOG_02175	2.87e-213	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
DMNEPPOG_02176	3.38e-166	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
DMNEPPOG_02177	4.3e-40	-	-	-	-	-	-	-	-
DMNEPPOG_02178	6.15e-181	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
DMNEPPOG_02179	9.39e-80	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
DMNEPPOG_02180	1.9e-79	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
DMNEPPOG_02181	2.69e-227	mocA	-	-	S	-	-	-	Oxidoreductase
DMNEPPOG_02182	1.03e-303	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
DMNEPPOG_02183	2.76e-74	chbA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
DMNEPPOG_02184	4.49e-93	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
DMNEPPOG_02186	7.67e-07	-	-	-	-	-	-	-	-
DMNEPPOG_02187	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
DMNEPPOG_02188	4.22e-308	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
DMNEPPOG_02189	2.96e-144	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DMNEPPOG_02190	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
DMNEPPOG_02191	9.73e-230	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
DMNEPPOG_02192	1.24e-103	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
DMNEPPOG_02193	4.05e-205	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
DMNEPPOG_02194	9.08e-260	-	-	-	M	-	-	-	Glycosyltransferase like family 2
DMNEPPOG_02196	1.02e-20	-	-	-	-	-	-	-	-
DMNEPPOG_02197	1.09e-253	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
DMNEPPOG_02198	4.58e-217	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
DMNEPPOG_02200	2.44e-210	-	4.2.1.46	-	GM	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Male sterility protein
DMNEPPOG_02201	3.26e-185	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DMNEPPOG_02202	7.2e-43	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
DMNEPPOG_02204	9.37e-59	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
DMNEPPOG_02205	1e-111	-	-	-	I	ko:K01066	-	ko00000,ko01000	Carboxylesterase family
DMNEPPOG_02206	6.36e-161	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
DMNEPPOG_02207	5e-55	yqeB	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
DMNEPPOG_02210	1.14e-187	cadA	-	-	P	-	-	-	P-type ATPase
DMNEPPOG_02212	1.47e-16	-	-	-	-	-	-	-	-
DMNEPPOG_02213	1.94e-142	is18	-	-	L	-	-	-	Integrase core domain
DMNEPPOG_02214	2.31e-48	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
DMNEPPOG_02216	9.27e-31	-	-	-	-	-	-	-	-
DMNEPPOG_02217	1e-146	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
DMNEPPOG_02218	2.95e-34	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
DMNEPPOG_02219	4.94e-20	-	-	-	-	-	-	-	-
DMNEPPOG_02221	4.33e-105	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
DMNEPPOG_02222	3.59e-107	repA	-	-	S	-	-	-	Replication initiator protein A
DMNEPPOG_02227	6.5e-23	-	-	-	M	-	-	-	Psort location Cellwall, score
DMNEPPOG_02231	1.44e-16	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
DMNEPPOG_02236	6.81e-52	-	-	-	V	-	-	-	antibiotic catabolic process
DMNEPPOG_02237	3.31e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3801)
DMNEPPOG_02238	2.77e-154	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
DMNEPPOG_02239	1.74e-21	-	-	-	-	-	-	-	-
DMNEPPOG_02240	2.22e-33	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
DMNEPPOG_02241	8.96e-22	-	-	-	U	-	-	-	PrgI family protein
DMNEPPOG_02242	3.95e-313	-	-	-	U	-	-	-	AAA-like domain
DMNEPPOG_02243	8.12e-46	-	-	-	M	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
DMNEPPOG_02247	1.41e-24	-	-	-	L	-	-	-	IrrE N-terminal-like domain
DMNEPPOG_02248	6.06e-38	-	-	-	L	-	-	-	IrrE N-terminal-like domain
DMNEPPOG_02250	1.16e-12	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
DMNEPPOG_02251	2.67e-118	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
DMNEPPOG_02252	6.17e-80	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
DMNEPPOG_02253	9.38e-86	-	-	-	G	-	-	-	COG0662 Mannose-6-phosphate isomerase
DMNEPPOG_02254	1.58e-109	is18	-	-	L	-	-	-	COG2801 Transposase and inactivated derivatives
DMNEPPOG_02255	3.06e-74	-	-	-	L	-	-	-	Integrase core domain
DMNEPPOG_02256	2.48e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
DMNEPPOG_02257	9.38e-82	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
DMNEPPOG_02258	1.75e-50	-	-	-	M	-	-	-	Glycosyl transferases group 1
DMNEPPOG_02259	1.4e-56	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
DMNEPPOG_02261	4.16e-44	-	-	-	S	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
DMNEPPOG_02262	4.51e-169	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
DMNEPPOG_02263	2.6e-218	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
DMNEPPOG_02264	1.23e-156	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
DMNEPPOG_02265	3.3e-198	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
DMNEPPOG_02266	6.16e-18	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
DMNEPPOG_02267	1.46e-40	rgpAc	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	Domain of unknown function (DUF1972)
DMNEPPOG_02268	2.03e-153	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
DMNEPPOG_02269	4.15e-179	epsB	-	-	M	-	-	-	biosynthesis protein
DMNEPPOG_02270	1.23e-168	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
DMNEPPOG_02271	1.21e-51	-	-	-	K	-	-	-	Protein of unknown function (DUF4065)
DMNEPPOG_02272	1.2e-105	ccl	-	-	S	-	-	-	QueT transporter
DMNEPPOG_02273	1.04e-159	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
DMNEPPOG_02274	8.55e-49	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
DMNEPPOG_02275	1.55e-62	-	-	-	K	-	-	-	sequence-specific DNA binding
DMNEPPOG_02276	4.87e-148	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
DMNEPPOG_02277	2.13e-228	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
DMNEPPOG_02278	4.99e-251	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
DMNEPPOG_02279	3.01e-227	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMNEPPOG_02280	1.4e-208	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMNEPPOG_02281	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
DMNEPPOG_02282	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
DMNEPPOG_02283	4.1e-130	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DMNEPPOG_02284	9.1e-300	-	-	-	L	ko:K07485	-	ko00000	Transposase
DMNEPPOG_02285	1.29e-168	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
DMNEPPOG_02286	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
DMNEPPOG_02287	1.7e-190	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
DMNEPPOG_02288	2.39e-109	-	-	-	-	-	-	-	-
DMNEPPOG_02289	5.19e-67	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system cellobiose-specific component IIA
DMNEPPOG_02290	5.99e-267	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
DMNEPPOG_02291	6.59e-90	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
DMNEPPOG_02293	3.79e-173	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DMNEPPOG_02294	1.7e-123	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DMNEPPOG_02295	0.0	galA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
DMNEPPOG_02296	9.02e-175	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
DMNEPPOG_02297	3.4e-175	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
DMNEPPOG_02298	0.0	-	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Helix-hairpin-helix containing domain
DMNEPPOG_02299	5.08e-102	-	-	-	-	-	-	-	-
DMNEPPOG_02300	5.33e-76	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
DMNEPPOG_02301	3.39e-186	frlD1	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
DMNEPPOG_02302	1.1e-131	hyuA	-	-	EQ	-	-	-	Hydantoinase/oxoprolinase N-terminal region
DMNEPPOG_02303	1.12e-174	-	-	-	-	-	-	-	-
DMNEPPOG_02304	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF1524)
DMNEPPOG_02305	1.22e-78	-	3.1.21.3	-	L	ko:K01154	-	ko00000,ko01000,ko02048	Restriction modification system DNA specificity domain
DMNEPPOG_02306	4.99e-223	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DMNEPPOG_02307	4.25e-47	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
DMNEPPOG_02308	4.93e-49	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	phosphopyruvate hydratase activity
DMNEPPOG_02310	1.58e-91	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DMNEPPOG_02311	1.06e-71	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DMNEPPOG_02312	0.0	-	-	-	L	-	-	-	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DMNEPPOG_02314	8.26e-104	-	-	-	-	-	-	-	-
DMNEPPOG_02315	2.1e-27	-	-	-	-	-	-	-	-
DMNEPPOG_02316	1.26e-212	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
DMNEPPOG_02317	0.0	-	-	-	M	-	-	-	domain protein
DMNEPPOG_02318	7.04e-102	-	-	-	-	-	-	-	-
DMNEPPOG_02319	5.94e-148	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
DMNEPPOG_02320	2.83e-152	-	-	-	GM	-	-	-	NmrA-like family
DMNEPPOG_02321	5.54e-214	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
DMNEPPOG_02322	2.9e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DMNEPPOG_02323	0.0	aldA	1.2.1.21, 1.2.1.22	-	C	ko:K07248	ko00620,ko00630,ko01120,map00620,map00630,map01120	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family
DMNEPPOG_02324	3.38e-170	-	3.6.3.35	-	P	ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
DMNEPPOG_02325	2.51e-186	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
DMNEPPOG_02326	6.58e-226	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
DMNEPPOG_02327	1.23e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
DMNEPPOG_02328	2.22e-144	-	-	-	P	-	-	-	Cation efflux family
DMNEPPOG_02329	1.53e-35	-	-	-	-	-	-	-	-
DMNEPPOG_02330	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
DMNEPPOG_02331	4.42e-306	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
DMNEPPOG_02332	1.14e-72	-	-	-	-	-	-	-	-
DMNEPPOG_02333	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
DMNEPPOG_02334	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
DMNEPPOG_02335	6.42e-28	-	-	-	-	-	-	-	-
DMNEPPOG_02336	1.88e-174	-	-	-	-	-	-	-	-
DMNEPPOG_02337	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
DMNEPPOG_02338	2.31e-277	yqiG	-	-	C	-	-	-	Oxidoreductase
DMNEPPOG_02339	3.51e-166	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
DMNEPPOG_02340	1.45e-231	ydhF	-	-	S	-	-	-	Aldo keto reductase
DMNEPPOG_02344	4.55e-137	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
DMNEPPOG_02345	1.18e-72	-	-	-	S	-	-	-	Enterocin A Immunity
DMNEPPOG_02346	1.66e-05	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
DMNEPPOG_02347	5.62e-75	-	-	-	-	-	-	-	-
DMNEPPOG_02350	1.06e-71	-	-	-	S	-	-	-	Protein of unknown function DUF262
DMNEPPOG_02351	5.99e-28	-	-	-	L	-	-	-	BsuBI/PstI restriction endonuclease C-terminus
DMNEPPOG_02353	6.36e-119	-	-	-	L	-	-	-	Eco57I restriction-modification methylase
DMNEPPOG_02354	2.67e-88	-	-	-	K	ko:K07467	-	ko00000	Replication initiation factor
DMNEPPOG_02355	3e-256	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
DMNEPPOG_02356	4.88e-210	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
DMNEPPOG_02357	4.1e-51	-	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DMNEPPOG_02359	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
DMNEPPOG_02360	8.03e-229	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
DMNEPPOG_02362	3.38e-56	-	-	-	-	-	-	-	-
DMNEPPOG_02363	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
DMNEPPOG_02364	1.04e-64	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
DMNEPPOG_02365	5.87e-109	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
DMNEPPOG_02366	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
DMNEPPOG_02367	1.51e-29	-	-	-	-	-	-	-	-
DMNEPPOG_02368	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
DMNEPPOG_02369	1.97e-230	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
DMNEPPOG_02370	3.71e-105	yjhE	-	-	S	-	-	-	Phage tail protein
DMNEPPOG_02371	1.8e-306	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
DMNEPPOG_02372	3.32e-239	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
DMNEPPOG_02373	4.03e-164	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
DMNEPPOG_02374	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
DMNEPPOG_02375	6.31e-173	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DMNEPPOG_02376	0.0	-	-	-	E	-	-	-	Amino Acid
DMNEPPOG_02377	2.01e-210	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
DMNEPPOG_02378	4.57e-304	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DMNEPPOG_02379	9.19e-206	nodB3	-	-	G	-	-	-	Polysaccharide deacetylase
DMNEPPOG_02380	3.7e-124	-	-	-	S	-	-	-	Glucosyl transferase GtrII
DMNEPPOG_02381	1.7e-148	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
DMNEPPOG_02382	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
DMNEPPOG_02383	1.42e-216	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
DMNEPPOG_02384	6.35e-177	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
DMNEPPOG_02385	7.71e-192	ORF00048	-	-	-	-	-	-	-
DMNEPPOG_02386	3.23e-75	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
DMNEPPOG_02387	4.01e-139	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
DMNEPPOG_02388	6.03e-114	-	-	-	K	-	-	-	GNAT family
DMNEPPOG_02389	2.68e-135	kptA	-	-	J	ko:K07559	-	ko00000,ko01000,ko03016	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
DMNEPPOG_02390	3.61e-55	-	-	-	-	-	-	-	-
DMNEPPOG_02391	1.43e-307	citM	-	-	C	ko:K03300	-	ko00000	Citrate transporter
DMNEPPOG_02392	3.17e-71	-	-	-	-	-	-	-	-
DMNEPPOG_02393	1.71e-62	oadG	-	-	I	-	-	-	Biotin-requiring enzyme
DMNEPPOG_02394	5.58e-251	oadB	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Na+-transporting oxaloacetate decarboxylase beta subunit
DMNEPPOG_02395	3.26e-07	-	-	-	-	-	-	-	-
DMNEPPOG_02396	4.66e-232	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
DMNEPPOG_02397	3.41e-65	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
DMNEPPOG_02398	7.46e-201	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
DMNEPPOG_02399	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
DMNEPPOG_02400	3.38e-122	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
DMNEPPOG_02401	0.0	oadA	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Conserved carboxylase domain
DMNEPPOG_02402	4.14e-163	citR	-	-	K	-	-	-	FCD
DMNEPPOG_02403	1.99e-199	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
DMNEPPOG_02404	7.43e-97	-	-	-	-	-	-	-	-
DMNEPPOG_02405	1.61e-41	-	-	-	-	-	-	-	-
DMNEPPOG_02406	1.25e-201	-	-	-	I	-	-	-	alpha/beta hydrolase fold
DMNEPPOG_02407	2.44e-208	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
DMNEPPOG_02408	1.26e-151	sodA	1.15.1.1	-	C	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DMNEPPOG_02409	1.43e-25	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
DMNEPPOG_02410	8.02e-114	-	-	-	-	-	-	-	-
DMNEPPOG_02411	8.59e-249	-	-	-	S	-	-	-	Protein of unknown function C-terminal (DUF3324)
DMNEPPOG_02412	8.44e-128	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
DMNEPPOG_02413	8.32e-128	-	-	-	-	-	-	-	-
DMNEPPOG_02414	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
DMNEPPOG_02415	4.15e-170	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
DMNEPPOG_02417	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
DMNEPPOG_02418	5.4e-155	-	-	-	K	-	-	-	Mga helix-turn-helix domain
DMNEPPOG_02419	3.02e-205	-	-	-	K	-	-	-	Mga helix-turn-helix domain
DMNEPPOG_02420	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
DMNEPPOG_02421	1.33e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DMNEPPOG_02422	1.23e-292	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
DMNEPPOG_02423	9.16e-244	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
DMNEPPOG_02424	1.09e-251	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
DMNEPPOG_02425	0.0	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DMNEPPOG_02426	2.96e-78	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DMNEPPOG_02427	2.04e-68	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
DMNEPPOG_02428	6.02e-242	-	-	-	E	-	-	-	M42 glutamyl aminopeptidase
DMNEPPOG_02429	0.0	-	-	-	GKT	ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DMNEPPOG_02430	4.24e-310	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
DMNEPPOG_02431	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
DMNEPPOG_02432	2.16e-156	-	-	-	S	ko:K03824	-	ko00000,ko01000	Acetyltransferase (GNAT) family
DMNEPPOG_02435	2.92e-81	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
DMNEPPOG_02436	6.91e-314	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
DMNEPPOG_02437	2.8e-144	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
DMNEPPOG_02438	1.76e-168	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DMNEPPOG_02439	1.07e-108	thiW	-	-	S	-	-	-	Thiamine-precursor transporter protein (ThiW)
DMNEPPOG_02440	6.12e-194	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DMNEPPOG_02441	5.42e-141	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
DMNEPPOG_02442	2.31e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
DMNEPPOG_02443	0.0	-	-	-	E	-	-	-	Amino acid permease
DMNEPPOG_02444	7e-47	-	-	-	-	-	-	-	-
DMNEPPOG_02445	2.08e-240	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
DMNEPPOG_02446	5.41e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
DMNEPPOG_02447	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
DMNEPPOG_02448	4.84e-198	rbsC	-	-	U	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
DMNEPPOG_02449	1.71e-215	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
DMNEPPOG_02450	3.3e-208	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DMNEPPOG_02451	3.09e-56	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
DMNEPPOG_02452	0.0	pbpC	-	-	M	ko:K21467	-	ko00000,ko01011	NTF2-like N-terminal transpeptidase domain
DMNEPPOG_02453	7.42e-311	-	-	-	EGP	-	-	-	Major Facilitator
DMNEPPOG_02454	3.79e-96	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
DMNEPPOG_02455	4.65e-134	-	-	-	-	-	-	-	-
DMNEPPOG_02456	4.22e-41	-	-	-	-	-	-	-	-
DMNEPPOG_02457	1.49e-84	-	-	-	-	-	-	-	-
DMNEPPOG_02458	4.45e-45	-	-	-	-	-	-	-	-
DMNEPPOG_02459	3.54e-176	ypaC	-	-	Q	-	-	-	Methyltransferase domain
DMNEPPOG_02460	0.0	-	-	-	S	-	-	-	ABC transporter
DMNEPPOG_02461	2.59e-227	draG	-	-	O	-	-	-	ADP-ribosylglycohydrolase
DMNEPPOG_02462	1.26e-139	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
DMNEPPOG_02463	2.19e-54	-	-	-	-	-	-	-	-
DMNEPPOG_02464	1.54e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
DMNEPPOG_02465	3.16e-186	-	-	-	M	-	-	-	Glycosyltransferase like family 2
DMNEPPOG_02466	7.68e-174	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
DMNEPPOG_02467	3.46e-103	-	-	-	T	-	-	-	Sh3 type 3 domain protein
DMNEPPOG_02468	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
DMNEPPOG_02469	3.97e-255	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
DMNEPPOG_02470	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
DMNEPPOG_02471	2.25e-207	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
DMNEPPOG_02472	1.04e-211	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
DMNEPPOG_02473	5.98e-173	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
DMNEPPOG_02474	1.01e-167	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
DMNEPPOG_02475	3.74e-75	-	-	-	-	-	-	-	-
DMNEPPOG_02476	2.58e-253	-	-	-	S	-	-	-	Protein conserved in bacteria
DMNEPPOG_02477	5.32e-207	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
DMNEPPOG_02478	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
DMNEPPOG_02479	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
DMNEPPOG_02480	1.99e-192	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
DMNEPPOG_02481	2.43e-207	-	-	-	S	-	-	-	Glycosyltransferase like family 2
DMNEPPOG_02482	7.56e-165	welB	-	-	S	-	-	-	Glycosyltransferase like family 2
DMNEPPOG_02483	6.41e-196	-	-	-	S	-	-	-	Glycosyl transferase family 2
DMNEPPOG_02484	3.01e-315	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
DMNEPPOG_02485	3.44e-41	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
DMNEPPOG_02486	5.18e-204	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
DMNEPPOG_02487	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
DMNEPPOG_02488	5.16e-217	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
DMNEPPOG_02489	3.12e-187	gntR	-	-	K	-	-	-	rpiR family
DMNEPPOG_02490	8.67e-88	yodA	-	-	S	-	-	-	Tautomerase enzyme
DMNEPPOG_02491	1.15e-203	iolJ	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
DMNEPPOG_02492	3.02e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
DMNEPPOG_02493	2.2e-176	-	-	-	S	-	-	-	Putative threonine/serine exporter
DMNEPPOG_02494	2.51e-98	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
DMNEPPOG_02496	5.04e-44	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
DMNEPPOG_02497	4.87e-181	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
DMNEPPOG_02498	1.73e-190	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
DMNEPPOG_02499	1.1e-182	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
DMNEPPOG_02500	1.23e-179	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
DMNEPPOG_02501	1.16e-159	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
DMNEPPOG_02502	7.59e-214	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
DMNEPPOG_02503	2.88e-306	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DMNEPPOG_02504	4.79e-151	-	-	-	G	-	-	-	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
DMNEPPOG_02505	1.01e-149	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DMNEPPOG_02506	3.24e-293	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DMNEPPOG_02507	3.82e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
DMNEPPOG_02508	3.18e-210	p75	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
DMNEPPOG_02511	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
DMNEPPOG_02512	4.55e-206	-	-	-	-	-	-	-	-
DMNEPPOG_02513	1.75e-157	-	-	-	-	-	-	-	-
DMNEPPOG_02514	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
DMNEPPOG_02515	1.73e-307	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
DMNEPPOG_02516	1.2e-121	-	-	-	-	-	-	-	-
DMNEPPOG_02517	0.0	strH	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Gram-positive signal peptide protein, YSIRK family
DMNEPPOG_02518	9.12e-249	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
DMNEPPOG_02519	5.43e-167	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
DMNEPPOG_02520	9.86e-282	agaS	-	-	G	ko:K02082	-	ko00000,ko01000	SIS domain
DMNEPPOG_02521	2.26e-288	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DMNEPPOG_02522	0.0	bgaC	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
DMNEPPOG_02523	5.61e-108	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
DMNEPPOG_02524	4.68e-206	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
DMNEPPOG_02525	3.66e-187	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
DMNEPPOG_02526	2.72e-85	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
DMNEPPOG_02527	9.8e-247	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
DMNEPPOG_02529	1.5e-44	-	-	-	-	-	-	-	-
DMNEPPOG_02530	6.09e-53	-	-	-	-	-	-	-	-
DMNEPPOG_02531	4.23e-287	-	-	-	EGP	-	-	-	Transmembrane secretion effector
DMNEPPOG_02532	5.68e-280	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DMNEPPOG_02533	4.65e-192	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DMNEPPOG_02535	5.95e-54	-	-	-	-	-	-	-	-
DMNEPPOG_02536	1.38e-295	-	-	-	S	-	-	-	Membrane
DMNEPPOG_02537	5.43e-190	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
DMNEPPOG_02538	0.0	-	-	-	M	-	-	-	Cna protein B-type domain
DMNEPPOG_02539	2.12e-309	-	-	-	-	-	-	-	-
DMNEPPOG_02540	0.0	-	-	-	M	-	-	-	domain protein
DMNEPPOG_02541	8.99e-133	-	-	-	-	-	-	-	-
DMNEPPOG_02542	9.31e-294	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
DMNEPPOG_02543	9.85e-263	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
DMNEPPOG_02544	3.71e-146	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DMNEPPOG_02545	8.68e-74	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
DMNEPPOG_02546	9.6e-81	-	-	-	-	-	-	-	-
DMNEPPOG_02547	7.34e-177	-	-	-	-	-	-	-	-
DMNEPPOG_02548	6.69e-61	-	-	-	S	-	-	-	Enterocin A Immunity
DMNEPPOG_02549	1.66e-42	-	-	-	S	-	-	-	Enterocin A Immunity
DMNEPPOG_02550	3.61e-61	spiA	-	-	K	-	-	-	TRANSCRIPTIONal
DMNEPPOG_02551	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
DMNEPPOG_02553	5.75e-72	-	-	-	-	-	-	-	-
DMNEPPOG_02554	5.05e-313	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
DMNEPPOG_02555	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
DMNEPPOG_02557	6e-173	-	2.7.13.3	-	T	ko:K02476,ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
DMNEPPOG_02558	7.99e-184	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
DMNEPPOG_02560	0.0	-	-	-	EGP	-	-	-	Major Facilitator
DMNEPPOG_02561	2.86e-161	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
DMNEPPOG_02562	4.29e-109	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DMNEPPOG_02563	5.2e-106	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DMNEPPOG_02564	5.52e-208	-	-	-	S	-	-	-	Alpha beta hydrolase
DMNEPPOG_02565	8.13e-82	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
DMNEPPOG_02566	1.23e-163	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
DMNEPPOG_02567	4.41e-20	-	-	-	-	-	-	-	-
DMNEPPOG_02568	3.82e-133	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
DMNEPPOG_02569	2.83e-205	-	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
DMNEPPOG_02570	3.16e-262	-	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
DMNEPPOG_02572	9.68e-226	-	-	-	EP	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMNEPPOG_02573	2.08e-215	-	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DMNEPPOG_02574	0.0	-	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
DMNEPPOG_02575	1.19e-164	-	-	-	S	-	-	-	DJ-1/PfpI family
DMNEPPOG_02576	2.12e-70	-	-	-	K	-	-	-	Transcriptional
DMNEPPOG_02577	6.68e-52	-	-	-	-	-	-	-	-
DMNEPPOG_02578	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
DMNEPPOG_02579	0.0	-	-	-	V	ko:K06147,ko:K06148,ko:K11085,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter transmembrane region
DMNEPPOG_02581	3.24e-89	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
DMNEPPOG_02582	7.96e-20	-	2.7.1.39	-	S	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Phosphotransferase enzyme family
DMNEPPOG_02583	0.0	-	-	-	M	-	-	-	LysM domain
DMNEPPOG_02584	3.38e-173	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
DMNEPPOG_02585	1.23e-176	-	-	-	K	-	-	-	DeoR C terminal sensor domain
DMNEPPOG_02587	7.74e-68	lciIC	-	-	K	-	-	-	Helix-turn-helix domain
DMNEPPOG_02588	7.5e-128	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
DMNEPPOG_02589	7.79e-192	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
DMNEPPOG_02590	2.09e-98	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
DMNEPPOG_02591	8.4e-150	-	-	-	-	-	-	-	-
DMNEPPOG_02592	6.44e-43	-	-	-	M	-	-	-	Sortase family
DMNEPPOG_02593	5.79e-83	-	-	-	M	-	-	-	Sortase family
DMNEPPOG_02594	8.73e-262	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
DMNEPPOG_02595	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DMNEPPOG_02596	1.18e-255	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DMNEPPOG_02597	1.98e-279	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
DMNEPPOG_02598	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
DMNEPPOG_02599	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
DMNEPPOG_02600	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
DMNEPPOG_02601	4.25e-220	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DMNEPPOG_02602	1.38e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
DMNEPPOG_02603	6.27e-220	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DMNEPPOG_02604	6.31e-312	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DMNEPPOG_02605	4.9e-192	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
DMNEPPOG_02606	2.01e-89	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DMNEPPOG_02607	7.28e-144	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
DMNEPPOG_02608	9.35e-15	-	-	-	-	-	-	-	-
DMNEPPOG_02609	3.91e-109	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
DMNEPPOG_02610	0.000409	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
DMNEPPOG_02611	1.09e-227	-	-	-	-	-	-	-	-
DMNEPPOG_02612	6.35e-174	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DMNEPPOG_02613	2.91e-189	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
DMNEPPOG_02614	1.44e-141	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DMNEPPOG_02615	6.51e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DMNEPPOG_02616	9.34e-225	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
DMNEPPOG_02617	0.0	cps2E	-	-	M	-	-	-	Bacterial sugar transferase
DMNEPPOG_02618	1.11e-166	-	-	-	-	-	-	-	-
DMNEPPOG_02619	0.0	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
DMNEPPOG_02620	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
DMNEPPOG_02621	1.73e-219	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
DMNEPPOG_02622	4.43e-135	-	-	-	-	-	-	-	-
DMNEPPOG_02623	8.49e-217	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
DMNEPPOG_02624	6.22e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
DMNEPPOG_02625	4.8e-109	yvbK	-	-	K	-	-	-	GNAT family
DMNEPPOG_02626	1.45e-149	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
DMNEPPOG_02627	2.27e-132	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
DMNEPPOG_02628	6.23e-303	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
DMNEPPOG_02629	1.15e-261	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DMNEPPOG_02630	1.16e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DMNEPPOG_02631	7.65e-136	-	-	-	-	-	-	-	-
DMNEPPOG_02632	6.04e-137	-	-	-	-	-	-	-	-
DMNEPPOG_02633	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
DMNEPPOG_02634	7.87e-144	vanZ	-	-	V	-	-	-	VanZ like family
DMNEPPOG_02635	4.66e-196	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
DMNEPPOG_02636	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
DMNEPPOG_02637	8.89e-290	-	-	-	L	-	-	-	Pfam:Integrase_AP2
DMNEPPOG_02640	4.86e-45	-	-	-	-	-	-	-	-
DMNEPPOG_02641	1.1e-89	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
DMNEPPOG_02644	3.23e-171	-	-	-	-	-	-	-	-
DMNEPPOG_02645	5.78e-287	inlJ	-	-	M	-	-	-	MucBP domain
DMNEPPOG_02646	5.49e-261	yacL	-	-	S	-	-	-	domain protein
DMNEPPOG_02647	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DMNEPPOG_02648	4.85e-130	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTPase
DMNEPPOG_02649	1e-66	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
DMNEPPOG_02650	5.93e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
DMNEPPOG_02651	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
DMNEPPOG_02652	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
DMNEPPOG_02653	5.42e-254	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
DMNEPPOG_02654	1.18e-273	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
DMNEPPOG_02655	3.35e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
DMNEPPOG_02656	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
DMNEPPOG_02657	0.0	ppdK	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the PEP-utilizing enzyme family
DMNEPPOG_02658	3.68e-136	ccpN	-	-	K	-	-	-	Domain in cystathionine beta-synthase and other proteins.
DMNEPPOG_02659	2.81e-157	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DMNEPPOG_02660	4.71e-263	-	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
DMNEPPOG_02661	5.25e-61	-	-	-	-	-	-	-	-
DMNEPPOG_02662	5.98e-265	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
DMNEPPOG_02663	1.59e-28	yhjA	-	-	K	-	-	-	CsbD-like
DMNEPPOG_02664	9.25e-118	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DMNEPPOG_02665	2.64e-131	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DMNEPPOG_02666	3.02e-275	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
DMNEPPOG_02667	2.31e-41	udp	2.4.2.3	-	F	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Phosphorylase superfamily
DMNEPPOG_02668	3.35e-125	-	-	-	S	-	-	-	Phospholipase A2
DMNEPPOG_02670	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
DMNEPPOG_02671	1.35e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
DMNEPPOG_02672	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
DMNEPPOG_02673	2.31e-277	-	-	-	-	-	-	-	-
DMNEPPOG_02674	1.93e-316	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DMNEPPOG_02675	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
DMNEPPOG_02676	4.34e-75	cadC5	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
DMNEPPOG_02677	0.0	-	3.6.3.6	-	P	ko:K01535	ko00190,map00190	ko00000,ko00001,ko01000	Cation transporter/ATPase, N-terminus
DMNEPPOG_02678	1.78e-208	lysR5	-	-	K	-	-	-	LysR substrate binding domain
DMNEPPOG_02679	3.32e-263	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DMNEPPOG_02680	1.91e-46	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
DMNEPPOG_02681	2.26e-215	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
DMNEPPOG_02682	3.78e-170	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
DMNEPPOG_02683	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
DMNEPPOG_02684	1.45e-172	-	-	-	-	-	-	-	-
DMNEPPOG_02685	4e-133	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
DMNEPPOG_02686	0.0	-	-	-	-	-	-	-	-
DMNEPPOG_02687	1.03e-77	-	-	-	T	-	-	-	Calcineurin-like phosphoesterase superfamily domain
DMNEPPOG_02688	1.28e-89	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
DMNEPPOG_02689	1.29e-122	-	-	-	-	-	-	-	-
DMNEPPOG_02690	1.25e-113	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
DMNEPPOG_02691	9.65e-163	-	-	-	-	-	-	-	-
DMNEPPOG_02692	8.53e-139	-	-	-	-	-	-	-	-
DMNEPPOG_02693	6.74e-173	-	-	-	-	-	-	-	-
DMNEPPOG_02694	0.0	frdC	1.3.5.1, 1.3.5.4	-	C	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	ko00000,ko00001,ko00002,ko01000	HI0933-like protein
DMNEPPOG_02695	5.13e-267	-	-	-	GKT	-	-	-	transcriptional antiterminator
DMNEPPOG_02696	1.39e-223	-	-	-	GKT	-	-	-	transcriptional antiterminator
DMNEPPOG_02697	4.1e-67	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DMNEPPOG_02698	1.96e-292	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
DMNEPPOG_02699	2.22e-93	-	-	-	-	-	-	-	-
DMNEPPOG_02700	6.47e-208	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
DMNEPPOG_02701	1.64e-151	-	-	-	S	-	-	-	Zeta toxin
DMNEPPOG_02702	3.2e-203	-	-	-	K	-	-	-	Sugar-specific transcriptional regulator TrmB
DMNEPPOG_02703	9.64e-191	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
DMNEPPOG_02704	5.02e-230	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
DMNEPPOG_02705	1.91e-191	-	3.1.1.24	-	S	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Alpha/beta hydrolase family
DMNEPPOG_02708	0.000152	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
DMNEPPOG_02710	1.36e-285	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
DMNEPPOG_02712	0.000469	-	-	-	S	-	-	-	Ribbon-helix-helix protein, copG family
DMNEPPOG_02717	4.06e-243	-	-	-	M	ko:K21471,ko:K21472	-	ko00000,ko01000,ko01002,ko01011	cysteine-type peptidase activity
DMNEPPOG_02718	0.0	-	-	-	S	-	-	-	COG0433 Predicted ATPase
DMNEPPOG_02719	3.07e-135	-	-	-	-	-	-	-	-
DMNEPPOG_02721	2.1e-296	-	-	-	S	-	-	-	domain, Protein
DMNEPPOG_02722	0.0	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
DMNEPPOG_02725	1.02e-284	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
DMNEPPOG_02726	9.02e-263	-	-	-	-	-	-	-	-
DMNEPPOG_02727	6.78e-42	-	-	-	-	-	-	-	-
DMNEPPOG_02729	1.43e-78	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
DMNEPPOG_02732	3.59e-227	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DMNEPPOG_02737	3.71e-94	-	-	-	-	-	-	-	-
DMNEPPOG_02738	8.34e-155	-	-	-	S	-	-	-	sequence-specific DNA binding
DMNEPPOG_02739	1.46e-50	-	-	-	S	-	-	-	sequence-specific DNA binding
DMNEPPOG_02748	2.64e-103	-	-	-	S	-	-	-	Siphovirus Gp157
DMNEPPOG_02749	5.24e-168	-	-	-	S	-	-	-	AAA domain
DMNEPPOG_02750	1.05e-131	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
DMNEPPOG_02751	4.29e-149	-	-	-	S	-	-	-	calcium ion binding
DMNEPPOG_02752	2.81e-297	-	-	-	S	-	-	-	DNA helicase activity
DMNEPPOG_02755	2.48e-39	-	-	-	-	-	-	-	-
DMNEPPOG_02756	4.76e-73	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
DMNEPPOG_02757	1.09e-29	-	-	-	-	-	-	-	-
DMNEPPOG_02758	9.04e-34	-	-	-	-	-	-	-	-
DMNEPPOG_02759	6.58e-164	-	-	-	L	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
DMNEPPOG_02764	8.58e-28	-	-	-	-	-	-	-	-
DMNEPPOG_02766	1.49e-77	-	-	-	Q	-	-	-	DNA (cytosine-5-)-methyltransferase activity
DMNEPPOG_02768	1.94e-86	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
DMNEPPOG_02769	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
DMNEPPOG_02770	1.71e-184	-	-	-	L	ko:K07485	-	ko00000	Transposase
DMNEPPOG_02773	0.000235	-	-	-	S	-	-	-	Ribbon-helix-helix protein, copG family
DMNEPPOG_02775	3.9e-285	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
DMNEPPOG_02777	0.0	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
DMNEPPOG_02778	1.06e-11	-	-	-	S	-	-	-	Putative Holin-like Toxin (Hol-Tox)
DMNEPPOG_02779	2.39e-85	-	-	-	-	-	-	-	-
DMNEPPOG_02780	3.48e-23	-	-	-	-	-	-	-	-
DMNEPPOG_02781	1.31e-103	-	-	-	-	-	-	-	-
DMNEPPOG_02783	8.2e-102	-	-	-	-	-	-	-	-
DMNEPPOG_02784	1.28e-199	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
DMNEPPOG_02786	6.49e-28	-	-	-	-	-	-	-	-
DMNEPPOG_02788	2.08e-214	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
DMNEPPOG_02789	1.23e-25	-	-	-	-	-	-	-	-
DMNEPPOG_02791	5.81e-130	-	-	-	D	-	-	-	AAA domain
DMNEPPOG_02792	4.2e-101	repA	-	-	S	-	-	-	Replication initiator protein A
DMNEPPOG_02799	6.82e-11	-	-	-	M	-	-	-	Peptidase_C39 like family
DMNEPPOG_02800	4.3e-39	-	-	-	M	-	-	-	Peptidase_C39 like family
DMNEPPOG_02801	3.7e-28	-	-	-	M	-	-	-	Peptidase_C39 like family
DMNEPPOG_02802	1.47e-59	-	-	-	M	-	-	-	Psort location Cellwall, score
DMNEPPOG_02804	8.18e-14	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
DMNEPPOG_02807	8.92e-105	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
DMNEPPOG_02808	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
DMNEPPOG_02809	1.52e-57	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
DMNEPPOG_02810	1.98e-280	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
DMNEPPOG_02812	1.58e-220	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DMNEPPOG_02813	1.13e-252	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
DMNEPPOG_02814	2.57e-293	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
DMNEPPOG_02815	0.0	ybeC	-	-	E	-	-	-	amino acid
DMNEPPOG_02816	8.3e-123	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	DNA-templated transcription, initiation
DMNEPPOG_02844	4.87e-173	-	-	-	-	-	-	-	-
DMNEPPOG_02845	2.33e-25	-	-	-	E	-	-	-	Zn peptidase
DMNEPPOG_02846	1.51e-80	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DMNEPPOG_02849	4.03e-202	ps305	-	-	S	-	-	-	Protein of unknown function (Hypoth_ymh)
DMNEPPOG_02850	9.07e-179	-	-	-	S	-	-	-	ORF6N domain
DMNEPPOG_02852	1.66e-59	-	-	-	S	-	-	-	Domain of unknown function (DUF1883)
DMNEPPOG_02858	7.76e-181	-	-	-	L	-	-	-	Helix-turn-helix domain
DMNEPPOG_02859	2.94e-198	pi346	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
DMNEPPOG_02861	3.84e-94	-	-	-	-	-	-	-	-
DMNEPPOG_02862	6.1e-172	-	-	-	-	-	-	-	-
DMNEPPOG_02865	4.76e-105	-	-	-	-	-	-	-	-
DMNEPPOG_02867	4.62e-193	-	-	-	EG	-	-	-	EamA-like transporter family
DMNEPPOG_02868	1.35e-97	-	-	-	L	-	-	-	NUDIX domain
DMNEPPOG_02869	4.9e-83	-	-	-	-	-	-	-	-
DMNEPPOG_02870	5e-252	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DMNEPPOG_02871	1.03e-240	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DMNEPPOG_02872	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
DMNEPPOG_02873	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
DMNEPPOG_02874	4.4e-116	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
DMNEPPOG_02875	6.4e-282	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
DMNEPPOG_02876	3.48e-215	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DMNEPPOG_02877	9.39e-181	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
DMNEPPOG_02879	5.26e-183	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DMNEPPOG_02883	4.92e-201	p40	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain
DMNEPPOG_02884	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
DMNEPPOG_02885	1.76e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DMNEPPOG_02886	4.12e-128	-	-	-	K	-	-	-	transcriptional regulator
DMNEPPOG_02887	1.03e-195	-	-	-	G	-	-	-	Sucrose-6F-phosphate phosphohydrolase
DMNEPPOG_02888	4.92e-65	-	-	-	-	-	-	-	-
DMNEPPOG_02891	1.67e-227	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
DMNEPPOG_02893	1.04e-44	-	-	-	-	-	-	-	-
DMNEPPOG_02897	1.72e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF1642)
DMNEPPOG_02899	1.27e-25	-	-	-	-	-	-	-	-
DMNEPPOG_02900	9.27e-86	-	-	-	S	-	-	-	magnesium ion binding
DMNEPPOG_02901	1.14e-44	-	-	-	-	-	-	-	-
DMNEPPOG_02903	9.58e-165	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
DMNEPPOG_02904	1.01e-71	-	-	-	L	-	-	-	Replication initiation and membrane attachment
DMNEPPOG_02905	3.07e-189	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
DMNEPPOG_02906	5.51e-205	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
DMNEPPOG_02908	5.09e-23	-	-	-	-	-	-	-	-
DMNEPPOG_02910	6.6e-129	-	-	-	-	-	-	-	-
DMNEPPOG_02914	7.53e-10	-	-	-	K	-	-	-	sequence-specific DNA binding
DMNEPPOG_02915	2.66e-74	-	-	-	K	-	-	-	Helix-turn-helix domain
DMNEPPOG_02916	3.29e-99	-	-	-	E	-	-	-	Zn peptidase
DMNEPPOG_02917	2.99e-139	-	-	-	-	-	-	-	-
DMNEPPOG_02918	9.47e-70	-	-	-	-	-	-	-	-
DMNEPPOG_02919	7.46e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
DMNEPPOG_02920	1.62e-159	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	proteolysis
DMNEPPOG_02921	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
DMNEPPOG_02922	0.0	-	-	-	L	-	-	-	ATPase domain of DNA mismatch repair MUTS family
DMNEPPOG_02923	3.79e-147	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
DMNEPPOG_02924	1.9e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
DMNEPPOG_02925	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
DMNEPPOG_02926	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DMNEPPOG_02927	1.72e-140	epsG	-	-	M	-	-	-	Glycosyltransferase like family 2
DMNEPPOG_02928	1.16e-268	proP	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
DMNEPPOG_02930	1.33e-17	-	-	-	S	-	-	-	YvrJ protein family
DMNEPPOG_02931	1.92e-183	-	-	-	M	-	-	-	hydrolase, family 25
DMNEPPOG_02932	2.9e-171	ypiA	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
DMNEPPOG_02933	5.95e-147	-	-	-	C	-	-	-	Flavodoxin
DMNEPPOG_02934	6.23e-113	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DMNEPPOG_02935	5.69e-238	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
DMNEPPOG_02936	7.08e-154	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DMNEPPOG_02937	3.74e-53	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DMNEPPOG_02938	9.99e-86	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
DMNEPPOG_02939	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
DMNEPPOG_02940	7.51e-194	-	-	-	S	-	-	-	hydrolase
DMNEPPOG_02942	3.05e-111	repA	-	-	S	-	-	-	Replication initiator protein A
DMNEPPOG_02943	6.29e-126	-	-	-	D	-	-	-	Cellulose biosynthesis protein BcsQ
DMNEPPOG_02945	3.47e-08	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
DMNEPPOG_02946	2.01e-54	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
DMNEPPOG_02949	1.14e-148	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
DMNEPPOG_02950	3.83e-61	-	-	-	L	-	-	-	BRCA1 C Terminus (BRCT) domain
DMNEPPOG_02951	3.89e-76	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
DMNEPPOG_02952	2.54e-45	mdt(A)	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	transporter
DMNEPPOG_02953	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
DMNEPPOG_02954	1.28e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Transcriptional regulator
DMNEPPOG_02956	8.39e-126	-	-	-	D	-	-	-	AAA domain
DMNEPPOG_02958	6.62e-89	-	-	-	K	-	-	-	Primase C terminal 1 (PriCT-1)
DMNEPPOG_02959	1.69e-75	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
DMNEPPOG_02960	8.87e-87	-	-	-	L	-	-	-	Transposase
DMNEPPOG_02961	1.38e-40	-	-	-	L	-	-	-	Transposase DDE domain
DMNEPPOG_02963	6.75e-05	-	-	-	S	-	-	-	Ribbon-helix-helix protein, copG family
DMNEPPOG_02965	2.81e-124	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
DMNEPPOG_02967	2.58e-125	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
DMNEPPOG_02968	0.0	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
DMNEPPOG_02969	3.92e-26	-	-	-	-	-	-	-	-
DMNEPPOG_02970	2.22e-44	-	-	-	-	-	-	-	-
DMNEPPOG_02971	1.56e-182	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
DMNEPPOG_02973	9.54e-17	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
DMNEPPOG_02974	2.22e-93	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
DMNEPPOG_02977	2.01e-30	-	-	-	K	-	-	-	Sigma-54 interaction domain
DMNEPPOG_02978	2.56e-10	-	-	-	L	-	-	-	Helix-turn-helix domain
DMNEPPOG_02979	1.77e-56	-	-	-	-	-	-	-	-
DMNEPPOG_02980	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
DMNEPPOG_02982	3.46e-211	-	-	-	P	-	-	-	CorA-like Mg2+ transporter protein
DMNEPPOG_02983	3.71e-49	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	Natural resistance-associated macrophage protein
DMNEPPOG_02984	9.55e-73	-	-	-	L	-	-	-	Transposase DDE domain
DMNEPPOG_02985	4.49e-74	-	-	-	L	-	-	-	Transposase DDE domain
DMNEPPOG_02986	0.0	dld	1.1.5.12	-	C	ko:K03777	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	D-lactate dehydrogenase, membrane binding
DMNEPPOG_02987	3.41e-68	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
DMNEPPOG_02988	4.9e-201	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DMNEPPOG_02989	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
DMNEPPOG_02990	2.2e-273	-	-	-	G	-	-	-	Transporter, major facilitator family protein
DMNEPPOG_02991	1.19e-52	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
DMNEPPOG_02992	6.09e-60	-	-	-	L	-	-	-	Transposase DDE domain
DMNEPPOG_02993	1.44e-94	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
DMNEPPOG_02994	8.34e-196	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
DMNEPPOG_02995	2.61e-316	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
DMNEPPOG_02996	3.04e-119	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
DMNEPPOG_02997	4.31e-232	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
DMNEPPOG_02998	7.62e-180	-	-	-	M	-	-	-	Glycosyltransferase like family 2
DMNEPPOG_02999	3.15e-255	-	-	-	M	-	-	-	Glycosyl transferases group 1
DMNEPPOG_03000	9.3e-221	rgpAc	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	Domain of unknown function (DUF1972)
DMNEPPOG_03002	5.31e-96	-	-	-	S	-	-	-	YopX protein
DMNEPPOG_03005	1.94e-104	-	-	-	-	-	-	-	-
DMNEPPOG_03010	2.49e-297	-	-	-	-	-	-	-	-
DMNEPPOG_03011	8.27e-69	-	-	-	-	-	-	-	-
DMNEPPOG_03013	1.3e-32	-	-	-	-	-	-	-	-
DMNEPPOG_03014	1.09e-92	-	-	-	L	-	-	-	HNH nucleases
DMNEPPOG_03015	2.95e-101	-	-	-	S	-	-	-	Phage terminase, small subunit
DMNEPPOG_03016	2.14e-260	-	-	-	S	-	-	-	Phage Terminase
DMNEPPOG_03017	8.69e-192	licT2	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
DMNEPPOG_03018	0.0	bglH	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
DMNEPPOG_03019	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DMNEPPOG_03020	0.0	-	-	-	N	-	-	-	domain, Protein
DMNEPPOG_03022	4.89e-186	-	-	-	S	-	-	-	Cell surface protein
DMNEPPOG_03024	8.37e-244	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
DMNEPPOG_03026	2.37e-91	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
DMNEPPOG_03027	5.11e-93	yqeB	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
DMNEPPOG_03028	3.7e-110	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase
DMNEPPOG_03029	2.16e-231	-	-	-	L	-	-	-	ATPase domain of DNA mismatch repair MUTS family
DMNEPPOG_03030	4.25e-144	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
DMNEPPOG_03031	5.68e-172	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
DMNEPPOG_03032	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
DMNEPPOG_03033	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DMNEPPOG_03034	4.18e-151	epsG	-	-	M	-	-	-	Glycosyltransferase like family 2
DMNEPPOG_03035	4.14e-259	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
DMNEPPOG_03036	1.64e-202	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
DMNEPPOG_03037	1.52e-199	-	-	-	-	-	-	-	-
DMNEPPOG_03038	2.67e-197	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
DMNEPPOG_03039	1.29e-182	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
DMNEPPOG_03040	1.83e-09	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	RNA-directed DNA polymerase
DMNEPPOG_03041	1.13e-116	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
DMNEPPOG_03043	3.02e-32	-	-	-	L	-	-	-	Initiator Replication protein
DMNEPPOG_03045	2.94e-99	-	-	-	L	-	-	-	Initiator Replication protein
DMNEPPOG_03047	3.31e-08	-	-	-	-	-	-	-	-
DMNEPPOG_03049	5.34e-72	-	-	-	S	-	-	-	AAA domain
DMNEPPOG_03051	3.34e-49	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
DMNEPPOG_03052	2.43e-94	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
DMNEPPOG_03054	7.37e-228	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
DMNEPPOG_03055	6.49e-185	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
DMNEPPOG_03056	4.85e-107	-	-	-	K	-	-	-	MerR HTH family regulatory protein
DMNEPPOG_03057	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
DMNEPPOG_03058	7.89e-268	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DMNEPPOG_03059	3.98e-91	-	-	-	-	-	-	-	-
DMNEPPOG_03063	1.98e-15	-	-	-	K	-	-	-	DNA binding
DMNEPPOG_03064	0.0	res	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
DMNEPPOG_03065	4.06e-296	mod	2.1.1.72	-	L	ko:K00571,ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
DMNEPPOG_03067	1.19e-98	-	-	-	L	-	-	-	Initiator Replication protein
DMNEPPOG_03069	7.82e-06	-	-	-	-	-	-	-	-
DMNEPPOG_03071	5.55e-70	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
DMNEPPOG_03072	4.09e-131	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DMNEPPOG_03073	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
DMNEPPOG_03075	6.85e-83	-	-	-	L	-	-	-	Transposase DDE domain
DMNEPPOG_03076	2.43e-206	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	PRD domain
DMNEPPOG_03077	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
DMNEPPOG_03078	0.0	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DMNEPPOG_03079	2.65e-67	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
DMNEPPOG_03080	1.33e-91	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
DMNEPPOG_03082	1.75e-61	-	-	-	L	-	-	-	hmm pf02796
DMNEPPOG_03083	9.65e-220	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
DMNEPPOG_03084	2.17e-84	-	-	-	S	-	-	-	Core-2/I-Branching enzyme
DMNEPPOG_03085	1.02e-108	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
DMNEPPOG_03086	2.05e-229	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
DMNEPPOG_03087	2.22e-154	yqgG	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
DMNEPPOG_03088	4.52e-160	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
DMNEPPOG_03089	0.00034	-	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Psort location CytoplasmicMembrane, score
DMNEPPOG_03090	3.19e-64	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
DMNEPPOG_03093	2.87e-60	-	-	-	L	-	-	-	Protein involved in initiation of plasmid replication
DMNEPPOG_03097	1.81e-298	-	-	-	G	-	-	-	Polysaccharide deacetylase
DMNEPPOG_03101	5.24e-115	-	-	-	D	-	-	-	AAA domain
DMNEPPOG_03102	6.62e-89	-	-	-	K	-	-	-	Primase C terminal 1 (PriCT-1)
DMNEPPOG_03104	1.27e-15	-	-	-	-	-	-	-	-
DMNEPPOG_03107	1.66e-188	-	-	-	S	-	-	-	CAAX protease self-immunity
DMNEPPOG_03108	1.29e-186	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DMNEPPOG_03109	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
DMNEPPOG_03110	2.46e-68	-	-	-	L	-	-	-	Transposase DDE domain
DMNEPPOG_03111	2.19e-39	-	-	-	S	-	-	-	Protein of unknown function DUF262
DMNEPPOG_03113	4.92e-186	-	-	-	S	-	-	-	Septin
DMNEPPOG_03114	0.0	merA	1.16.1.1	-	C	ko:K00520,ko:K21739	-	ko00000,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DMNEPPOG_03115	3.62e-18	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
DMNEPPOG_03117	5.19e-90	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
DMNEPPOG_03120	1.48e-26	-	-	-	L	-	-	-	RePlication protein
DMNEPPOG_03123	7.88e-42	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	COG2076 Membrane transporters of cations and cationic drugs
DMNEPPOG_03124	2.13e-163	-	-	-	L	ko:K07498	-	ko00000	Transposase IS66 family
DMNEPPOG_03126	5.3e-93	-	-	-	S	-	-	-	Plasmid replication protein
DMNEPPOG_03127	4.53e-210	-	-	-	M	-	-	-	Peptidase_C39 like family
DMNEPPOG_03128	5.01e-14	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
DMNEPPOG_03129	2.11e-69	-	-	-	L	ko:K07483	-	ko00000	4.5 Transposon and IS
DMNEPPOG_03130	4.74e-158	-	-	-	L	-	-	-	Initiator Replication protein
DMNEPPOG_03132	2.47e-125	-	-	-	L	-	-	-	Transposase
DMNEPPOG_03133	1.29e-151	-	-	-	L	-	-	-	Transposase
DMNEPPOG_03134	2.97e-41	-	-	-	L	ko:K07481	-	ko00000	Transposase
DMNEPPOG_03135	0.000324	-	-	-	S	-	-	-	CsbD-like
DMNEPPOG_03137	8.18e-206	-	-	-	-	-	-	-	-
DMNEPPOG_03138	3.44e-64	-	-	-	-	-	-	-	-
DMNEPPOG_03139	9.96e-140	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
DMNEPPOG_03140	1.53e-97	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
DMNEPPOG_03141	9.46e-103	udp	2.4.2.3	-	F	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Phosphorylase superfamily
DMNEPPOG_03142	4.48e-62	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
DMNEPPOG_03143	8.14e-79	-	-	-	S	-	-	-	MucBP domain
DMNEPPOG_03144	9.73e-109	-	-	-	-	-	-	-	-
DMNEPPOG_03146	1.95e-200	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
DMNEPPOG_03147	1.56e-141	-	-	-	L	-	-	-	Helix-turn-helix domain
DMNEPPOG_03148	1.45e-46	-	-	-	-	-	-	-	-
DMNEPPOG_03149	1.22e-60	repA	-	-	S	-	-	-	Replication initiator protein A
DMNEPPOG_03150	6.94e-59	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
DMNEPPOG_03151	1.11e-111	-	-	-	-	-	-	-	-
DMNEPPOG_03152	4.15e-270	-	-	-	L	-	-	-	Transposase DDE domain
DMNEPPOG_03153	7.01e-57	-	-	-	-	-	-	-	-
DMNEPPOG_03154	0.0	-	-	-	L	-	-	-	Transposase DDE domain
DMNEPPOG_03157	2.82e-71	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
DMNEPPOG_03158	1.77e-60	-	-	-	L	-	-	-	Integrase core domain
DMNEPPOG_03159	6.62e-244	sthIR	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
DMNEPPOG_03160	3.27e-256	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
DMNEPPOG_03163	4.22e-194	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
DMNEPPOG_03164	2.31e-99	sthIR	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
DMNEPPOG_03166	4.75e-202	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
DMNEPPOG_03167	7.56e-78	-	-	-	S	-	-	-	Phage Mu protein F like protein
DMNEPPOG_03168	1.55e-140	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
DMNEPPOG_03169	1.4e-59	-	-	-	M	-	-	-	domain protein
DMNEPPOG_03171	8.29e-74	-	-	-	-	-	-	-	-
DMNEPPOG_03172	3.52e-56	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
DMNEPPOG_03177	3.06e-35	-	-	-	L	-	-	-	Helix-turn-helix domain
DMNEPPOG_03178	3.06e-35	-	-	-	L	-	-	-	Helix-turn-helix domain