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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HPEMBLHF_00009	8.63e-188	-	5.2.1.8	-	O	ko:K03773	-	ko00000,ko01000,ko03110	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase
HPEMBLHF_00010	1.04e-136	-	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HPEMBLHF_00011	7.9e-269	-	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
HPEMBLHF_00012	5.98e-207	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HPEMBLHF_00013	0.0	-	-	-	P	ko:K03455	-	ko00000	TrkA-N domain
HPEMBLHF_00014	2.23e-163	-	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
HPEMBLHF_00021	3.83e-133	panZ	-	-	K	-	-	-	-acetyltransferase
HPEMBLHF_00022	9.72e-225	-	-	-	E	ko:K00612	-	ko00000,ko01000	lipolytic protein G-D-S-L family
HPEMBLHF_00023	2.91e-220	-	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Pyridine nucleotide-disulphide oxidoreductase
HPEMBLHF_00024	0.0	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
HPEMBLHF_00025	2.24e-175	-	-	-	-	-	-	-	-
HPEMBLHF_00027	9.55e-242	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HPEMBLHF_00028	2.63e-208	-	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Polyprenyl synthetase
HPEMBLHF_00029	1.19e-199	-	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
HPEMBLHF_00030	3.45e-157	-	1.4.3.5	-	H	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)
HPEMBLHF_00031	8.81e-205	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
HPEMBLHF_00032	0.0	-	-	-	G	-	-	-	Trehalase
HPEMBLHF_00033	0.0	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HPEMBLHF_00034	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HPEMBLHF_00035	1.1e-34	-	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L34
HPEMBLHF_00036	2e-75	-	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	Ribonuclease P
HPEMBLHF_00037	4.61e-61	-	-	-	S	ko:K08998	-	ko00000	Haemolytic
HPEMBLHF_00038	0.0	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins
HPEMBLHF_00039	0.0	-	1.4.1.13, 1.4.1.14	-	E	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
HPEMBLHF_00040	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HPEMBLHF_00041	0.0	-	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HPEMBLHF_00042	1.48e-270	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase small chain, CPSase domain
HPEMBLHF_00043	6.96e-265	-	4.2.1.47	-	M	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HPEMBLHF_00044	3.08e-267	fcl	1.1.1.271	-	GM	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
HPEMBLHF_00045	8.01e-294	-	-	-	C	-	-	-	Na+/H+ antiporter family
HPEMBLHF_00046	1.01e-276	-	-	-	-	-	-	-	-
HPEMBLHF_00047	1.33e-226	-	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphomannose isomerase type I
HPEMBLHF_00048	1.29e-181	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
HPEMBLHF_00049	7.54e-115	ispF	4.6.1.12	-	I	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HPEMBLHF_00050	5.6e-180	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
HPEMBLHF_00051	0.0	-	-	-	M	-	-	-	PFAM glycosyl transferase family 51
HPEMBLHF_00052	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HPEMBLHF_00053	6.23e-97	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transport protein ExbD/TolR
HPEMBLHF_00054	2.47e-180	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
HPEMBLHF_00055	0.0	-	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HPEMBLHF_00056	2.88e-96	-	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Predicted SPOUT methyltransferase
HPEMBLHF_00057	1.95e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S9/S16
HPEMBLHF_00058	2.79e-97	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HPEMBLHF_00059	1.07e-30	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HPEMBLHF_00060	0.0	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HPEMBLHF_00061	1.81e-169	-	-	-	L	ko:K03630	-	ko00000	RadC-like JAB domain
HPEMBLHF_00063	4.69e-173	-	-	-	D	-	-	-	Phage-related minor tail protein
HPEMBLHF_00065	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HPEMBLHF_00066	1.13e-60	-	-	-	L	ko:K09747	-	ko00000	YbaB/EbfC DNA-binding family
HPEMBLHF_00067	1.09e-252	-	-	-	N	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease Exonuclease Phosphatase
HPEMBLHF_00068	0.0	-	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	DHHA2
HPEMBLHF_00070	1.57e-188	-	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
HPEMBLHF_00071	0.0	-	-	-	S	-	-	-	OPT oligopeptide transporter protein
HPEMBLHF_00073	0.0	-	-	-	G	-	-	-	Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain
HPEMBLHF_00074	2.23e-72	-	-	-	M	-	-	-	self proteolysis
HPEMBLHF_00079	3.44e-19	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HPEMBLHF_00081	0.0	kdpA	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HPEMBLHF_00082	0.0	kdpB	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HPEMBLHF_00083	1.3e-125	kdpC	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HPEMBLHF_00085	1.06e-260	-	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Osmosensitive K+ channel His kinase sensor domain
HPEMBLHF_00086	8.73e-234	-	2.7.11.1	-	T	ko:K08884,ko:K12132,ko:K20333	ko02024,map02024	ko00000,ko00001,ko01000,ko01001	PFAM Formylglycine-generating sulfatase enzyme
HPEMBLHF_00088	1.39e-194	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HPEMBLHF_00089	1.93e-138	-	-	-	K	ko:K03088	-	ko00000,ko03021	DNA-templated transcription, initiation
HPEMBLHF_00090	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HPEMBLHF_00091	2.44e-188	-	-	-	C	-	-	-	Aldo/keto reductase family
HPEMBLHF_00092	2.02e-56	-	-	-	C	-	-	-	Aldo/keto reductase family
HPEMBLHF_00093	1.77e-85	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HPEMBLHF_00094	3.32e-258	-	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
HPEMBLHF_00095	4.98e-284	-	-	-	-	-	-	-	-
HPEMBLHF_00096	0.0	-	-	-	S	-	-	-	von Willebrand factor type A domain
HPEMBLHF_00097	0.0	-	-	-	S	-	-	-	Aerotolerance regulator N-terminal
HPEMBLHF_00098	1.16e-207	-	-	-	S	-	-	-	Protein of unknown function DUF58
HPEMBLHF_00099	0.0	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
HPEMBLHF_00100	1.4e-238	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
HPEMBLHF_00101	0.0	-	-	-	-	-	-	-	-
HPEMBLHF_00102	1.01e-235	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HPEMBLHF_00103	1.58e-294	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
HPEMBLHF_00104	1.29e-236	-	-	-	E	-	-	-	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HPEMBLHF_00106	9.5e-201	-	-	-	O	-	-	-	stress-induced mitochondrial fusion
HPEMBLHF_00107	2.29e-208	-	-	-	S	ko:K07071	-	ko00000	Domain of unknown function (DUF1731)
HPEMBLHF_00108	5.98e-121	-	-	-	M	ko:K03098	-	ko00000,ko04147	Lipocalin-like domain
HPEMBLHF_00109	1.35e-236	-	1.1.1.86	-	E	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HPEMBLHF_00110	2.92e-189	-	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HPEMBLHF_00111	2.65e-150	-	-	-	K	-	-	-	Transcriptional regulator
HPEMBLHF_00112	2.35e-265	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HPEMBLHF_00114	0.0	-	-	-	P	-	-	-	Sulfatase
HPEMBLHF_00115	1.04e-78	divIC	-	-	D	ko:K05589,ko:K13052	-	ko00000,ko03036	cell cycle
HPEMBLHF_00116	1.08e-303	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HPEMBLHF_00117	3.8e-309	-	-	-	E	-	-	-	Aminotransferase class I and II
HPEMBLHF_00119	2.15e-197	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HPEMBLHF_00120	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Alpha galactosidase A
HPEMBLHF_00121	1.04e-49	-	-	-	-	-	-	-	-
HPEMBLHF_00122	1.45e-55	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
HPEMBLHF_00123	8.69e-232	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HPEMBLHF_00124	8.69e-96	-	-	-	L	ko:K07447	-	ko00000,ko01000	Likely ribonuclease with RNase H fold.
HPEMBLHF_00125	4.66e-257	-	2.7.7.13	-	M	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HPEMBLHF_00126	6.08e-164	-	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HPEMBLHF_00127	0.0	-	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	TopoisomeraseII
HPEMBLHF_00128	4.89e-201	ispE	2.7.1.148	-	I	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
HPEMBLHF_00130	0.0	-	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	HELICc2
HPEMBLHF_00131	1.33e-176	cbiO	-	-	P	ko:K02006,ko:K02008,ko:K16784,ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase activity
HPEMBLHF_00132	2.42e-195	cbiQ	-	-	P	ko:K02007,ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transmembrane transporter activity
HPEMBLHF_00133	8.77e-239	cbiM	-	-	P	ko:K02007,ko:K02009,ko:K16915	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt ion transport
HPEMBLHF_00135	5.69e-18	-	-	-	S	-	-	-	Lipocalin-like
HPEMBLHF_00136	1.85e-208	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HPEMBLHF_00137	1.81e-227	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HPEMBLHF_00138	1.06e-94	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L9, N-terminal domain
HPEMBLHF_00139	0.0	-	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	AICARFT/IMPCHase bienzyme
HPEMBLHF_00140	5.64e-173	pdxJ	2.6.99.2	-	H	ko:K03474	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HPEMBLHF_00141	9.05e-85	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	4'-phosphopantetheinyl transferase superfamily
HPEMBLHF_00143	0.0	pckG	4.1.1.32	-	C	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle
HPEMBLHF_00144	9.48e-165	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
HPEMBLHF_00145	0.0	-	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	RecG wedge domain
HPEMBLHF_00147	0.0	-	-	-	C	ko:K00184	-	ko00000	4Fe-4S dicluster domain
HPEMBLHF_00148	4.88e-177	-	-	-	C	-	-	-	Cytochrome c7 and related cytochrome c
HPEMBLHF_00149	1.44e-313	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HPEMBLHF_00151	1.9e-256	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Iron-containing alcohol dehydrogenase
HPEMBLHF_00153	0.0	-	-	-	S	-	-	-	pathogenesis
HPEMBLHF_00155	6.21e-39	-	-	-	-	-	-	-	-
HPEMBLHF_00156	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HPEMBLHF_00158	7.42e-230	-	-	-	CO	-	-	-	Thioredoxin-like
HPEMBLHF_00159	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
HPEMBLHF_00160	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
HPEMBLHF_00161	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (C) catalytic domain
HPEMBLHF_00162	2.35e-63	-	-	-	G	-	-	-	Cupin 2, conserved barrel domain protein
HPEMBLHF_00163	2.14e-92	ybfH	-	-	EG	-	-	-	spore germination
HPEMBLHF_00164	2.66e-306	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HPEMBLHF_00165	3.92e-119	-	2.1.1.113	-	L	ko:K00590	-	ko00000,ko01000,ko02048	Pfam:Methyltransf_26
HPEMBLHF_00166	9.7e-123	-	2.1.1.113	-	L	ko:K00590	-	ko00000,ko01000,ko02048	Putative RNA methylase family UPF0020
HPEMBLHF_00168	1.41e-82	-	-	-	L	-	-	-	AAA ATPase domain
HPEMBLHF_00169	7.5e-120	-	-	-	L	-	-	-	AAA ATPase domain
HPEMBLHF_00170	1.36e-49	-	-	-	S	-	-	-	Transposon-encoded protein TnpV
HPEMBLHF_00171	2.8e-71	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	EcoEI R protein C-terminal
HPEMBLHF_00172	6.31e-216	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
HPEMBLHF_00173	1.16e-67	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HPEMBLHF_00174	4.28e-50	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HPEMBLHF_00175	2.63e-156	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HPEMBLHF_00176	8.07e-32	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HPEMBLHF_00177	9.08e-36	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HPEMBLHF_00178	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HPEMBLHF_00179	1.42e-118	-	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HPEMBLHF_00180	1.06e-187	-	-	-	O	ko:K04083	-	ko00000,ko03110	Hsp33 protein
HPEMBLHF_00183	8.05e-231	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
HPEMBLHF_00185	9.78e-129	-	-	-	U	ko:K05595	-	ko00000,ko02000	MarC family integral membrane protein
HPEMBLHF_00186	4.5e-173	-	4.2.99.20	-	I	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Alpha/beta hydrolase family
HPEMBLHF_00187	1.46e-75	-	-	-	S	ko:K09954	-	ko00000	Putative quorum-sensing-regulated virulence factor
HPEMBLHF_00189	1.92e-46	-	-	-	-	-	-	-	-
HPEMBLHF_00190	3.3e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF2589)
HPEMBLHF_00191	3.25e-183	-	-	-	-	-	-	-	-
HPEMBLHF_00192	2.59e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF2589)
HPEMBLHF_00193	1.88e-111	-	-	-	KT	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	phosphorelay signal transduction system
HPEMBLHF_00194	3.04e-302	-	-	-	C	-	-	-	4 iron, 4 sulfur cluster binding
HPEMBLHF_00195	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
HPEMBLHF_00196	3.65e-220	-	-	-	K	-	-	-	Transcriptional regulator
HPEMBLHF_00197	4.25e-178	-	-	-	C	-	-	-	aldo keto reductase
HPEMBLHF_00198	9.71e-185	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HPEMBLHF_00199	3.24e-272	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
HPEMBLHF_00200	9.26e-307	-	-	-	C	-	-	-	Carboxymuconolactone decarboxylase family
HPEMBLHF_00201	1.2e-158	-	-	-	IQ	-	-	-	Short chain dehydrogenase
HPEMBLHF_00202	3.72e-27	corC_1	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
HPEMBLHF_00204	4.21e-137	-	-	-	J	ko:K05808	-	ko00000,ko03009	Sigma 54 modulation/S30EA ribosomal protein C terminus
HPEMBLHF_00206	4.34e-09	-	-	-	M	-	-	-	major outer membrane lipoprotein
HPEMBLHF_00207	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HPEMBLHF_00209	7.07e-168	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
HPEMBLHF_00210	7.5e-306	-	-	-	C	-	-	-	Sulfatase-modifying factor enzyme 1
HPEMBLHF_00212	4.07e-48	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HPEMBLHF_00213	1.15e-05	-	-	-	-	-	-	-	-
HPEMBLHF_00214	0.000114	-	-	-	-	-	-	-	-
HPEMBLHF_00215	1.24e-47	XK27_09985	-	-	S	-	-	-	Protein of unknown function (DUF1232)
HPEMBLHF_00216	1.43e-194	-	-	-	S	ko:K07051	-	ko00000	TatD related DNase
HPEMBLHF_00217	8.94e-56	-	-	-	-	-	-	-	-
HPEMBLHF_00218	4.83e-163	-	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	-
HPEMBLHF_00219	0.0	-	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Fumarate reductase flavoprotein C-term
HPEMBLHF_00220	1.29e-187	-	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	2Fe-2S iron-sulfur cluster binding domain
HPEMBLHF_00222	7.67e-273	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HPEMBLHF_00223	8.4e-235	-	-	-	O	-	-	-	Trypsin-like peptidase domain
HPEMBLHF_00224	0.0	-	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Transglycosylase
HPEMBLHF_00225	4.71e-283	-	-	-	S	ko:K09760	-	ko00000	RmuC family
HPEMBLHF_00226	4.68e-170	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
HPEMBLHF_00227	1.25e-132	-	2.3.1.129	-	M	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	ko00000,ko00001,ko00002,ko01000,ko01005	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HPEMBLHF_00228	1.36e-185	-	-	-	S	-	-	-	RDD family
HPEMBLHF_00229	0.0	-	-	-	M	ko:K09808	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	MacB-like periplasmic core domain
HPEMBLHF_00232	3.08e-107	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
HPEMBLHF_00234	0.0	-	3.2.1.52	GH20	G	ko:K01207,ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko01501,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map01501,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
HPEMBLHF_00235	1.2e-299	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HPEMBLHF_00236	3.4e-227	-	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate synthetase A protein
HPEMBLHF_00237	1.68e-253	-	-	-	S	-	-	-	Putative S-adenosyl-L-methionine-dependent methyltransferase
HPEMBLHF_00238	0.0	cdr	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HPEMBLHF_00239	3.05e-68	bigR	-	-	K	-	-	-	transcriptional regulator
HPEMBLHF_00242	3.47e-214	-	-	-	S	-	-	-	MobA/MobL family
HPEMBLHF_00243	1.47e-50	-	-	-	S	-	-	-	Conjugal transfer protein TraD
HPEMBLHF_00244	5.14e-110	-	-	-	KT	-	-	-	Primase C terminal 1 (PriCT-1)
HPEMBLHF_00247	1.95e-45	-	-	-	S	-	-	-	Rop protein
HPEMBLHF_00248	3.11e-47	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
HPEMBLHF_00249	1.07e-32	-	-	-	S	-	-	-	MbeB-like, N-term conserved region
HPEMBLHF_00251	1.18e-127	-	-	-	-	-	-	-	-
HPEMBLHF_00256	0.0	-	-	-	-	-	-	-	-
HPEMBLHF_00257	2.34e-58	-	-	-	F	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HPEMBLHF_00258	2.31e-33	-	-	-	F	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HPEMBLHF_00259	2.4e-173	-	-	-	S	-	-	-	peptidoglycan biosynthetic process
HPEMBLHF_00260	1.85e-206	-	1.4.1.16	-	S	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
HPEMBLHF_00263	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HPEMBLHF_00264	9.06e-135	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	5,10-methylenetetrahydrofolate reductase
HPEMBLHF_00265	7.12e-152	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HPEMBLHF_00266	9.27e-77	queH	1.17.99.6	-	C	ko:K09765	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HPEMBLHF_00267	1.88e-231	-	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	prohibitin homologues
HPEMBLHF_00268	2.13e-118	-	-	-	-	-	-	-	-
HPEMBLHF_00269	0.0	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Insulinase (Peptidase family M16)
HPEMBLHF_00270	4.92e-50	-	-	-	-	-	-	-	-
HPEMBLHF_00271	1.13e-291	lpxK	2.7.1.130	-	M	ko:K00912	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)
HPEMBLHF_00272	2.93e-135	-	-	-	S	ko:K07164	-	ko00000	C4-type zinc ribbon domain
HPEMBLHF_00273	6.16e-262	-	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
HPEMBLHF_00274	1.5e-74	-	-	-	-	-	-	-	-
HPEMBLHF_00275	2.4e-190	-	3.6.1.66	-	S	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	MazG nucleotide pyrophosphohydrolase domain
HPEMBLHF_00276	2.41e-67	-	-	-	-	-	-	-	-
HPEMBLHF_00277	6.89e-180	-	-	-	S	-	-	-	competence protein
HPEMBLHF_00278	8.26e-101	-	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
HPEMBLHF_00282	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	Sulfatase
HPEMBLHF_00283	3.73e-143	-	-	-	-	-	-	-	-
HPEMBLHF_00284	5.26e-164	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
HPEMBLHF_00285	4.63e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HPEMBLHF_00286	4.62e-292	-	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	16S rRNA methyltransferase RsmB/F
HPEMBLHF_00287	2.35e-114	-	3.1.6.8	-	P	ko:K01134	ko00600,ko04142,map00600,map04142	ko00000,ko00001,ko01000	COG3119 Arylsulfatase A
HPEMBLHF_00288	2.59e-314	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Arginosuccinate synthase
HPEMBLHF_00290	2.79e-54	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HPEMBLHF_00291	6.95e-58	-	-	-	S	-	-	-	Zinc ribbon domain
HPEMBLHF_00292	4.77e-310	-	-	-	S	-	-	-	PFAM CBS domain containing protein
HPEMBLHF_00293	2.93e-150	-	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HII
HPEMBLHF_00294	4.83e-82	-	-	-	L	ko:K07460	-	ko00000	Uncharacterised protein family UPF0102
HPEMBLHF_00296	1.37e-176	-	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Indole-3-glycerol phosphate synthase
HPEMBLHF_00297	3.4e-229	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
HPEMBLHF_00298	1.39e-157	-	-	-	S	-	-	-	3D domain
HPEMBLHF_00299	2.07e-149	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HPEMBLHF_00300	9.91e-171	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
HPEMBLHF_00301	9.16e-111	aglS	-	-	U	ko:K03559	-	ko00000,ko02000	biopolymer transport protein
HPEMBLHF_00302	1.24e-98	exbD2	-	-	U	ko:K03559	-	ko00000,ko02000	biopolymer transport protein
HPEMBLHF_00303	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HPEMBLHF_00304	2.23e-194	-	-	-	-	-	-	-	-
HPEMBLHF_00305	2.58e-276	-	-	-	K	-	-	-	sequence-specific DNA binding
HPEMBLHF_00306	0.0	-	-	-	J	ko:K08301	-	ko00000,ko01000,ko03009,ko03019	Ribonuclease E/G family
HPEMBLHF_00307	5.06e-236	-	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Actin
HPEMBLHF_00308	0.0	lacZ_17	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
HPEMBLHF_00310	8.5e-259	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
HPEMBLHF_00312	6.16e-176	-	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
HPEMBLHF_00313	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate
HPEMBLHF_00314	2.62e-100	-	-	-	-	-	-	-	-
HPEMBLHF_00315	2.21e-165	-	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	SAICAR synthetase
HPEMBLHF_00316	0.0	-	-	-	K	-	-	-	Transcription elongation factor, N-terminal
HPEMBLHF_00317	0.0	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HPEMBLHF_00319	1.69e-170	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HPEMBLHF_00320	2.21e-278	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HPEMBLHF_00321	1.42e-205	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HPEMBLHF_00322	6.39e-200	-	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase, N-terminal
HPEMBLHF_00323	1.06e-109	-	-	-	S	ko:K15977	-	ko00000	DoxX
HPEMBLHF_00324	2.76e-292	-	4.2.1.129, 5.4.99.17	-	I	ko:K06045	ko00909,ko01110,map00909,map01110	ko00000,ko00001,ko01000	PFAM Prenyltransferase squalene oxidase
HPEMBLHF_00325	4.7e-193	-	-	-	-	-	-	-	-
HPEMBLHF_00326	1.18e-224	-	5.3.1.13	-	M	ko:K06041	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
HPEMBLHF_00327	9.39e-183	-	-	-	H	-	-	-	ThiF family
HPEMBLHF_00328	8.92e-111	-	-	-	U	-	-	-	response to pH
HPEMBLHF_00329	1.01e-223	-	-	-	-	-	-	-	-
HPEMBLHF_00330	7.6e-214	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HPEMBLHF_00332	0.0	-	-	-	G	-	-	-	Raffinose synthase or seed imbibition protein Sip1
HPEMBLHF_00333	6.08e-63	-	-	-	S	-	-	-	COGs COG4299 conserved
HPEMBLHF_00334	5.21e-111	-	-	-	S	-	-	-	COGs COG4299 conserved
HPEMBLHF_00335	8.4e-143	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HPEMBLHF_00336	0.0	-	3.4.16.4	-	M	ko:K05515	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein dimerisation domain
HPEMBLHF_00337	0.0	-	-	-	-	-	-	-	-
HPEMBLHF_00338	3.47e-216	-	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	ATP synthase A chain
HPEMBLHF_00339	1.65e-11	-	-	-	S	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	PFAM H transporting two-sector ATPase C subunit
HPEMBLHF_00340	2.53e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase B/B' CF(0)
HPEMBLHF_00341	6.46e-86	-	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase delta (OSCP) subunit
HPEMBLHF_00342	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HPEMBLHF_00343	1.83e-200	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HPEMBLHF_00344	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HPEMBLHF_00345	9.38e-86	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HPEMBLHF_00346	4.28e-141	-	-	-	-	-	-	-	-
HPEMBLHF_00347	3.8e-124	sprT	-	-	K	-	-	-	SprT-like family
HPEMBLHF_00348	9.26e-270	-	-	-	S	-	-	-	COGs COG4299 conserved
HPEMBLHF_00349	5.4e-285	-	2.6.1.59	-	M	ko:K02805	-	ko00000,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
HPEMBLHF_00350	2.86e-113	flmH	2.3.1.57	-	J	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HPEMBLHF_00351	7.63e-220	-	-	-	M	-	-	-	Glycosyl transferase family 2
HPEMBLHF_00352	3.11e-73	-	-	-	P	ko:K03297,ko:K11741	-	ko00000,ko02000	Multidrug Resistance protein
HPEMBLHF_00353	1.93e-77	-	-	-	P	ko:K03297,ko:K11741	-	ko00000,ko02000	Multidrug Resistance protein
HPEMBLHF_00356	3.35e-131	-	-	-	F	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HPEMBLHF_00357	0.0	-	2.6.1.62	-	H	ko:K00833	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HPEMBLHF_00358	2.06e-233	-	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Biotin and Thiamin Synthesis associated domain
HPEMBLHF_00359	0.0	-	-	-	P	-	-	-	Sulfatase
HPEMBLHF_00360	0.0	-	-	-	M	-	-	-	Bacterial membrane protein, YfhO
HPEMBLHF_00361	1.61e-290	-	-	-	O	ko:K09015	-	ko00000	Uncharacterized protein family (UPF0051)
HPEMBLHF_00362	0.0	-	-	-	O	ko:K09014	-	ko00000	Uncharacterized protein family (UPF0051)
HPEMBLHF_00363	1.02e-178	-	-	-	O	ko:K09013	-	ko00000,ko02000	ATPases associated with a variety of cellular activities
HPEMBLHF_00364	6.78e-100	-	-	-	P	ko:K09825	-	ko00000,ko03000	Ferric uptake regulator family
HPEMBLHF_00365	2.14e-57	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
HPEMBLHF_00366	1.93e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal prokaryotic L21 protein
HPEMBLHF_00367	5.76e-107	-	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
HPEMBLHF_00368	2.16e-199	-	-	-	S	ko:K06889	-	ko00000	alpha beta
HPEMBLHF_00370	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
HPEMBLHF_00371	0.0	-	-	-	-	-	-	-	-
HPEMBLHF_00372	7.39e-225	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HPEMBLHF_00374	3.02e-178	-	-	-	-	-	-	-	-
HPEMBLHF_00375	6.23e-127	-	-	-	L	-	-	-	Conserved hypothetical protein 95
HPEMBLHF_00376	1.18e-309	-	2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15	GT30	M	ko:K02527	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)
HPEMBLHF_00377	3.53e-228	-	-	-	S	-	-	-	Aspartyl protease
HPEMBLHF_00378	1.37e-271	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HPEMBLHF_00379	6.55e-155	-	6.3.2.5	-	H	ko:K21977	ko00770,map00770	ko00000,ko00001,ko00002,ko01000	DNA / pantothenate metabolism flavoprotein
HPEMBLHF_00380	1.66e-271	-	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
HPEMBLHF_00382	9.31e-23	-	-	-	K	ko:K03826	-	ko00000,ko01000	acetyltransferase
HPEMBLHF_00383	2.25e-20	-	-	-	K	ko:K03826	-	ko00000,ko01000	acetyltransferase
HPEMBLHF_00384	2.48e-173	-	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HPEMBLHF_00385	0.0	-	-	-	L	-	-	-	Polyphosphate kinase 2 (PPK2)
HPEMBLHF_00386	0.0	-	-	-	S	-	-	-	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HPEMBLHF_00387	2.31e-259	-	-	-	M	-	-	-	Peptidase family M23
HPEMBLHF_00389	8.37e-126	-	4.1.1.36	-	H	ko:K01598	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Flavoprotein
HPEMBLHF_00390	1.31e-81	-	-	-	DJ	-	-	-	Addiction module toxin, RelE StbE family
HPEMBLHF_00391	1.58e-206	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HPEMBLHF_00393	1.47e-138	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
HPEMBLHF_00394	0.0	-	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HPEMBLHF_00395	6.75e-245	-	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	AIR synthase related protein, N-terminal domain
HPEMBLHF_00396	1.15e-99	-	-	-	S	ko:K15977	-	ko00000	DoxX
HPEMBLHF_00397	2.07e-235	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HPEMBLHF_00398	0.0	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
HPEMBLHF_00399	2.21e-169	-	-	-	-	-	-	-	-
HPEMBLHF_00400	0.0	-	3.6.4.13	-	L	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DbpA RNA binding domain
HPEMBLHF_00401	0.0	-	-	-	P	ko:K01138	-	ko00000,ko01000	PA14 domain
HPEMBLHF_00402	2.16e-150	-	-	-	L	-	-	-	Membrane
HPEMBLHF_00404	0.0	gcvP	1.4.4.2	-	E	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HPEMBLHF_00405	6.67e-86	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HPEMBLHF_00406	3.19e-264	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Aminomethyltransferase folate-binding domain
HPEMBLHF_00407	1.11e-261	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HPEMBLHF_00408	1.42e-217	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HPEMBLHF_00409	6.26e-269	-	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
HPEMBLHF_00410	2.1e-269	-	-	-	M	-	-	-	Glycosyl transferase 4-like
HPEMBLHF_00411	3.12e-220	-	-	-	M	ko:K07276	-	ko00000	Mitochondrial fission ELM1
HPEMBLHF_00412	1.25e-266	-	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Domain of unknown function (DUF1730)
HPEMBLHF_00413	1.11e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HPEMBLHF_00414	3.5e-120	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HPEMBLHF_00415	7.24e-141	-	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S4/S9 N-terminal domain
HPEMBLHF_00416	1.64e-190	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
HPEMBLHF_00420	1.41e-120	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HPEMBLHF_00421	0.0	-	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase, barrel domain
HPEMBLHF_00422	1.55e-284	-	3.5.1.42	-	S	ko:K03742	ko00760,map00760	ko00000,ko00001,ko01000	Competence-damaged protein
HPEMBLHF_00423	1.85e-149	-	-	-	O	-	-	-	methyltransferase activity
HPEMBLHF_00424	3.76e-181	-	-	-	U	ko:K20276	ko02024,map02024	ko00000,ko00001	domain, Protein
HPEMBLHF_00425	0.0	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
HPEMBLHF_00426	1.56e-254	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Elongator protein 3, MiaB family, Radical SAM
HPEMBLHF_00427	1.48e-186	-	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SRP54-type protein, GTPase domain
HPEMBLHF_00428	6.86e-198	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HPEMBLHF_00429	7.87e-100	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HPEMBLHF_00430	5.32e-285	-	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase II
HPEMBLHF_00431	0.0	glnS	6.1.1.18	-	J	ko:K01886	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (E and Q), anti-codon binding domain
HPEMBLHF_00432	0.0	-	-	-	-	-	-	-	-
HPEMBLHF_00433	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
HPEMBLHF_00434	9.8e-259	-	-	-	S	-	-	-	ankyrin repeats
HPEMBLHF_00435	6.33e-313	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HPEMBLHF_00436	4.32e-44	-	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S21
HPEMBLHF_00437	0.0	-	2.7.1.167, 2.7.7.70	-	M	ko:K03272	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	pfkB family carbohydrate kinase
HPEMBLHF_00438	8.25e-131	-	5.3.1.28	-	G	ko:K03271	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
HPEMBLHF_00439	1.03e-116	-	3.1.3.82, 3.1.3.83	-	E	ko:K03273	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Polynucleotide kinase 3 phosphatase
HPEMBLHF_00440	7.25e-19	hyl	2.3.1.48, 3.2.1.169, 3.2.1.35	GH84	G	ko:K01197,ko:K15719	ko00531,ko01100,ko04931,map00531,map01100,map04931	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylhexosaminidase activity
HPEMBLHF_00441	5.58e-185	hyl	2.3.1.48, 3.2.1.169, 3.2.1.35	GH84	G	ko:K01197,ko:K15719	ko00531,ko01100,ko04931,map00531,map01100,map04931	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylhexosaminidase activity
HPEMBLHF_00443	5.81e-249	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	NMT1/THI5 like
HPEMBLHF_00444	7.44e-186	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPEMBLHF_00445	1.64e-194	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPEMBLHF_00446	2.68e-186	lpxD	2.3.1.191	-	M	ko:K02536	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HPEMBLHF_00447	1.48e-120	-	-	-	M	ko:K06142	-	ko00000	Outer membrane protein (OmpH-like)
HPEMBLHF_00448	1.39e-195	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HPEMBLHF_00449	5.24e-150	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPEMBLHF_00450	9.42e-116	-	-	-	-	-	-	-	-
HPEMBLHF_00451	2.41e-201	-	-	-	S	-	-	-	DisA bacterial checkpoint controller nucleotide-binding
HPEMBLHF_00453	1.7e-153	-	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	AAA domain
HPEMBLHF_00454	0.0	-	-	-	G	-	-	-	beta-N-acetylhexosaminidase activity
HPEMBLHF_00455	0.0	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
HPEMBLHF_00456	8.16e-179	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HPEMBLHF_00457	1.27e-172	-	-	-	NU	-	-	-	Prepilin-type N-terminal cleavage methylation domain
HPEMBLHF_00458	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	PFAM coagulation factor 5 8 type domain protein
HPEMBLHF_00459	9.86e-168	-	-	-	M	-	-	-	Peptidase family M23
HPEMBLHF_00460	1e-142	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HPEMBLHF_00461	1.64e-195	-	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HPEMBLHF_00464	0.0	-	-	-	S	-	-	-	Terminase
HPEMBLHF_00465	2.46e-215	-	-	-	D	ko:K19234,ko:K19236	ko01503,map01503	ko00000,ko00001,ko01002,ko01011	ErfK ybiS ycfS ynhG family protein
HPEMBLHF_00466	1.56e-59	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HPEMBLHF_00467	2.58e-73	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HPEMBLHF_00468	3.01e-49	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal_S15
HPEMBLHF_00469	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HPEMBLHF_00470	9.05e-313	tlyC	-	-	S	ko:K03699	-	ko00000,ko02042	PFAM CBS domain containing protein
HPEMBLHF_00471	1.88e-308	-	-	-	S	-	-	-	PFAM CBS domain containing protein
HPEMBLHF_00472	0.0	-	-	-	C	-	-	-	Cytochrome c554 and c-prime
HPEMBLHF_00473	1.39e-165	-	-	-	CO	-	-	-	Thioredoxin-like
HPEMBLHF_00474	1.1e-159	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HPEMBLHF_00475	2.61e-153	-	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Thiamine monophosphate synthase
HPEMBLHF_00476	4.25e-238	pyrD	1.3.5.2	-	F	ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
HPEMBLHF_00477	0.0	-	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase alpha chain like domain
HPEMBLHF_00478	5.21e-142	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HPEMBLHF_00479	0.0	-	4.1.1.15	-	E	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase conserved domain
HPEMBLHF_00480	0.0	-	-	-	-	-	-	-	-
HPEMBLHF_00482	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	PFAM Glycoside hydrolase, family 20, catalytic core
HPEMBLHF_00484	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
HPEMBLHF_00485	0.0	-	-	-	KT	ko:K02584	ko02020,map02020	ko00000,ko00001,ko03000	Bacterial regulatory protein, Fis family
HPEMBLHF_00486	3.78e-218	-	2.5.1.21	-	I	ko:K00801	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01006	Squalene/phytoene synthase
HPEMBLHF_00487	0.0	-	-	-	S	-	-	-	Fungal chitosanase of glycosyl hydrolase group 75
HPEMBLHF_00488	1.95e-186	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
HPEMBLHF_00489	8.38e-98	-	-	-	-	-	-	-	-
HPEMBLHF_00490	0.0	-	-	-	V	-	-	-	ABC-2 type transporter
HPEMBLHF_00493	2.32e-145	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
HPEMBLHF_00497	2.07e-299	-	-	-	MU	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	efflux transmembrane transporter activity
HPEMBLHF_00500	4.36e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Enoyl-CoA hydratase/isomerase
HPEMBLHF_00501	5.24e-257	-	-	-	S	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
HPEMBLHF_00503	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HPEMBLHF_00504	4.69e-79	rsfS	-	-	S	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HPEMBLHF_00505	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HPEMBLHF_00506	5.34e-140	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease
HPEMBLHF_00507	4.42e-164	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HPEMBLHF_00508	0.0	-	-	-	CO	-	-	-	Disulphide bond corrector protein DsbC
HPEMBLHF_00509	7.56e-94	-	-	-	O	-	-	-	OsmC-like protein
HPEMBLHF_00511	3.42e-111	-	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	Cytidine and deoxycytidylate deaminase zinc-binding region
HPEMBLHF_00512	0.0	-	-	-	EGIP	-	-	-	Phosphate acyltransferases
HPEMBLHF_00514	7.21e-205	-	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
HPEMBLHF_00515	0.0	-	-	-	P	ko:K02014	-	ko00000,ko02000	TonB dependent receptor
HPEMBLHF_00516	3.5e-168	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPEMBLHF_00517	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HPEMBLHF_00518	4.51e-148	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
HPEMBLHF_00519	3.4e-228	-	-	-	EP	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HPEMBLHF_00520	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	KH-domain-like of EngA bacterial GTPase enzymes, C-terminal
HPEMBLHF_00521	9.26e-249	-	-	-	S	ko:K07091	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Predicted permease YjgP/YjgQ family
HPEMBLHF_00522	2.6e-124	-	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Recombination protein O N terminal
HPEMBLHF_00523	5.43e-181	-	-	-	S	-	-	-	Tetratricopeptide repeat
HPEMBLHF_00524	0.0	dxs	2.2.1.7	-	HI	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HPEMBLHF_00525	3.08e-52	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease VII activity
HPEMBLHF_00526	0.0	-	-	-	O	-	-	-	C-terminal four TMM region of protein-O-mannosyltransferase
HPEMBLHF_00527	0.0	-	-	-	T	-	-	-	Bacterial regulatory protein, Fis family
HPEMBLHF_00528	1.82e-274	-	-	-	T	-	-	-	PAS domain
HPEMBLHF_00529	3.37e-97	-	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase superfamily
HPEMBLHF_00530	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	BPG-independent PGAM N-terminus (iPGM_N)
HPEMBLHF_00531	4.16e-85	-	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S12/S23
HPEMBLHF_00532	2.91e-104	-	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S7p/S5e
HPEMBLHF_00533	0.0	-	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HPEMBLHF_00534	3.67e-65	-	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S10p/S20e
HPEMBLHF_00535	6.41e-148	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HPEMBLHF_00536	9.43e-132	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L4/L1 family
HPEMBLHF_00537	8.72e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HPEMBLHF_00538	1.85e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HPEMBLHF_00539	1.05e-58	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HPEMBLHF_00540	4.05e-152	-	-	-	-	-	-	-	-
HPEMBLHF_00541	4.97e-70	-	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome
HPEMBLHF_00542	4.27e-155	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HPEMBLHF_00543	3.42e-97	-	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HPEMBLHF_00544	5.78e-35	-	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L29 protein
HPEMBLHF_00545	2.19e-56	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HPEMBLHF_00546	6.79e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HPEMBLHF_00547	7.23e-202	-	-	-	-	-	-	-	-
HPEMBLHF_00548	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HPEMBLHF_00549	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Domain of unknown function (DUF4982)
HPEMBLHF_00550	4.73e-254	-	5.2.1.8	-	O	ko:K03771	-	ko00000,ko01000,ko03110	SurA N-terminal domain
HPEMBLHF_00551	1.75e-169	-	2.5.1.39	-	H	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HPEMBLHF_00552	2.38e-141	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
HPEMBLHF_00558	1.9e-62	-	-	-	L	-	-	-	bacterial (prokaryotic) histone like domain
HPEMBLHF_00559	5.06e-200	-	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HII
HPEMBLHF_00560	2.43e-126	-	-	-	M	ko:K03642	-	ko00000	Lytic transglycolase
HPEMBLHF_00561	4.32e-174	-	-	-	F	-	-	-	NUDIX domain
HPEMBLHF_00562	1.22e-150	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Putative methyltransferase
HPEMBLHF_00563	1.39e-282	tgt	2.4.2.29	-	J	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HPEMBLHF_00564	5.64e-66	-	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
HPEMBLHF_00565	8.84e-184	-	-	-	DTZ	-	-	-	EF-hand, calcium binding motif
HPEMBLHF_00566	6.5e-215	-	-	-	L	ko:K03733	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
HPEMBLHF_00570	9.56e-51	-	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal protein S16
HPEMBLHF_00571	8.98e-128	aroK	2.7.1.71	-	E	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HPEMBLHF_00572	4.2e-242	-	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HPEMBLHF_00573	2e-79	-	-	-	FG	ko:K02503	-	ko00000,ko04147	HIT domain
HPEMBLHF_00574	2.03e-116	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HPEMBLHF_00575	2.73e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HPEMBLHF_00576	3.48e-246	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HPEMBLHF_00577	0.0	-	-	-	S	ko:K07037	-	ko00000	7TM receptor with intracellular HD hydrolase
HPEMBLHF_00578	2.36e-116	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HPEMBLHF_00580	1.88e-29	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPEMBLHF_00583	1.85e-07	-	-	-	L	-	-	-	Excalibur calcium-binding domain
HPEMBLHF_00586	2.3e-78	-	-	-	KT	-	-	-	Peptidase S24-like
HPEMBLHF_00590	1.15e-54	-	-	-	S	-	-	-	AAA domain
HPEMBLHF_00596	1.22e-42	-	-	-	L	-	-	-	D12 class N6 adenine-specific DNA methyltransferase
HPEMBLHF_00598	1.84e-136	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
HPEMBLHF_00602	1.49e-08	-	-	-	-	-	-	-	-
HPEMBLHF_00609	1.69e-128	-	-	-	S	-	-	-	Glycosyl hydrolase 108
HPEMBLHF_00610	3.86e-38	-	-	-	L	-	-	-	Mu-like prophage protein gp29
HPEMBLHF_00613	2.58e-69	-	-	-	MP	-	-	-	regulation of cell-substrate adhesion
HPEMBLHF_00625	1.44e-36	-	-	-	O	-	-	-	Trypsin-like peptidase domain
HPEMBLHF_00630	0.0	-	-	-	CO	-	-	-	Thioredoxin-like
HPEMBLHF_00631	4.69e-88	-	-	-	L	-	-	-	Initiator Replication protein
HPEMBLHF_00632	1.3e-73	traA	-	-	L	-	-	-	MobA MobL family protein
HPEMBLHF_00637	8.33e-31	-	-	-	M	-	-	-	self proteolysis
HPEMBLHF_00643	3.45e-104	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HPEMBLHF_00653	0.0	-	-	-	L	ko:K07495	-	ko00000	COG3385 FOG Transposase and inactivated derivatives
HPEMBLHF_00654	9.35e-98	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
HPEMBLHF_00655	0.0	-	-	-	L	-	-	-	TRCF
HPEMBLHF_00656	1.55e-294	-	-	-	-	-	-	-	-
HPEMBLHF_00657	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
HPEMBLHF_00658	6.05e-254	-	-	-	S	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HPEMBLHF_00660	6.5e-213	-	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	PHP domain
HPEMBLHF_00661	1.4e-259	-	2.3.1.8	-	C	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphate acetyl/butaryl transferase
HPEMBLHF_00662	1.65e-241	tilS	6.3.4.19	-	D	ko:K04075	-	ko00000,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HPEMBLHF_00663	2.59e-75	-	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HPEMBLHF_00667	5.41e-100	-	-	-	MP	-	-	-	regulation of cell-substrate adhesion
HPEMBLHF_00671	0.0	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP binding domain
HPEMBLHF_00672	1.83e-231	-	1.1.1.37	-	C	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible oxidation of malate to oxaloacetate
HPEMBLHF_00673	0.0	-	-	-	G	-	-	-	Glycogen debranching enzyme
HPEMBLHF_00674	0.0	-	-	-	M	-	-	-	NPCBM/NEW2 domain
HPEMBLHF_00675	0.0	-	-	-	M	ko:K04744	-	ko00000,ko02000	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HPEMBLHF_00676	2.42e-154	-	1.5.1.34	-	C	ko:K10679	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nitroreductase family
HPEMBLHF_00677	2.07e-190	-	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
HPEMBLHF_00678	3.71e-170	-	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
HPEMBLHF_00679	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HPEMBLHF_00682	8.47e-122	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	adenylate kinase activity
HPEMBLHF_00683	9.83e-164	-	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HPEMBLHF_00684	0.0	-	-	-	ET	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HPEMBLHF_00686	8.31e-253	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Semialdehyde dehydrogenase, NAD binding domain
HPEMBLHF_00687	1.73e-303	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HPEMBLHF_00688	2.79e-108	-	-	-	S	-	-	-	Putative zinc- or iron-chelating domain
HPEMBLHF_00689	1.03e-30	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
HPEMBLHF_00691	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	ATPases associated with a variety of cellular activities
HPEMBLHF_00692	3.16e-144	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
HPEMBLHF_00693	1e-120	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
HPEMBLHF_00694	2.87e-248	-	-	-	-	-	-	-	-
HPEMBLHF_00696	6.13e-174	-	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
HPEMBLHF_00697	3.01e-59	-	-	-	S	ko:K09131	-	ko00000	DUF167
HPEMBLHF_00698	1.16e-114	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HPEMBLHF_00699	6.64e-260	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HPEMBLHF_00700	1.56e-174	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HPEMBLHF_00701	1.41e-240	-	3.1.3.18	-	F	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
HPEMBLHF_00702	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
HPEMBLHF_00703	1.02e-228	-	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
HPEMBLHF_00704	0.0	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Peptidase S24-like
HPEMBLHF_00705	0.0	-	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HPEMBLHF_00706	1.04e-149	-	-	-	-	-	-	-	-
HPEMBLHF_00707	1.99e-165	pks6	-	-	Q	-	-	-	amino acid activation for nonribosomal peptide biosynthetic process
HPEMBLHF_00708	2.92e-172	-	-	-	S	-	-	-	Protein of unknown function (DUF3485)
HPEMBLHF_00709	1.69e-229	-	-	-	C	-	-	-	Transmembrane exosortase (Exosortase_EpsH)
HPEMBLHF_00710	4.58e-220	prs	2.7.6.1	-	EF	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HPEMBLHF_00711	1.51e-132	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HPEMBLHF_00713	1.48e-141	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
HPEMBLHF_00714	8.84e-146	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HPEMBLHF_00715	1.56e-60	-	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal protein S6
HPEMBLHF_00716	3.33e-207	-	1.1.1.262	-	H	ko:K00097	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Pyridoxal phosphate biosynthetic protein PdxA
HPEMBLHF_00719	4.59e-222	-	-	-	M	-	-	-	D-alanyl-D-alanine carboxypeptidase
HPEMBLHF_00720	3.82e-255	-	2.7.1.11, 2.7.1.90	-	G	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Phosphofructokinase
HPEMBLHF_00721	3.25e-218	-	-	-	L	-	-	-	Membrane
HPEMBLHF_00722	2.51e-172	zupT	-	-	P	ko:K07238	-	ko00000,ko02000	transporter
HPEMBLHF_00723	6.14e-235	-	-	-	CO	-	-	-	Protein of unknown function, DUF255
HPEMBLHF_00726	0.0	-	2.6.1.66	-	E	ko:K00835	ko00290,ko01100,ko01110,ko01130,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
HPEMBLHF_00727	4.28e-195	-	-	-	S	-	-	-	Domain of unknown function (DUF1732)
HPEMBLHF_00728	4.39e-145	-	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
HPEMBLHF_00729	0.0	-	-	-	P	-	-	-	Citrate transporter
HPEMBLHF_00730	7.58e-209	-	-	-	J	ko:K01894	-	ko00000,ko01000,ko01007,ko03016	tRNA synthetases class I (E and Q), catalytic domain
HPEMBLHF_00733	2.97e-215	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HPEMBLHF_00734	5.46e-170	-	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
HPEMBLHF_00736	7.65e-250	-	-	-	-	-	-	-	-
HPEMBLHF_00737	8.36e-164	-	-	-	S	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
HPEMBLHF_00738	7.74e-174	-	-	-	T	-	-	-	Outer membrane lipoprotein-sorting protein
HPEMBLHF_00739	1.96e-226	-	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HPEMBLHF_00740	0.0	secD	-	-	U	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HPEMBLHF_00742	7.92e-270	-	3.4.23.43	-	NOU	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
HPEMBLHF_00743	1.38e-257	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Possible lysine decarboxylase
HPEMBLHF_00744	2.95e-262	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPEMBLHF_00745	4.19e-87	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HPEMBLHF_00746	2.55e-216	-	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Acyl transferase domain
HPEMBLHF_00749	1.02e-163	-	-	-	S	-	-	-	HAD-hyrolase-like
HPEMBLHF_00750	1.19e-283	-	-	-	S	ko:K11720	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Predicted permease YjgP/YjgQ family
HPEMBLHF_00751	1.04e-269	-	-	-	E	-	-	-	serine-type peptidase activity
HPEMBLHF_00752	2.16e-303	-	-	-	M	-	-	-	OmpA family
HPEMBLHF_00753	5.78e-212	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HPEMBLHF_00754	0.0	-	-	-	M	-	-	-	Peptidase M60-like family
HPEMBLHF_00755	2.87e-288	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HPEMBLHF_00756	0.0	-	-	-	KT	-	-	-	Sigma factor PP2C-like phosphatases
HPEMBLHF_00757	5.45e-162	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
HPEMBLHF_00758	1.93e-241	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
HPEMBLHF_00759	3.26e-173	-	-	-	NU	ko:K02457,ko:K08084	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	protein transport across the cell outer membrane
HPEMBLHF_00760	5.24e-188	-	-	-	-	-	-	-	-
HPEMBLHF_00761	1.72e-245	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
HPEMBLHF_00762	4.68e-181	-	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
HPEMBLHF_00763	3.58e-238	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
HPEMBLHF_00764	0.0	hppA	3.6.1.1	-	C	ko:K15987	ko00190,map00190	ko00000,ko00001,ko01000	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane
HPEMBLHF_00768	0.0	-	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
HPEMBLHF_00769	0.0	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HPEMBLHF_00770	4.4e-173	-	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Indole-3-glycerol phosphate synthase
HPEMBLHF_00771	4.88e-154	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	N-(5'phosphoribosyl)anthranilate (PRA) isomerase
HPEMBLHF_00772	1.57e-281	-	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HPEMBLHF_00773	9.06e-187	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HPEMBLHF_00774	0.0	-	-	-	T	-	-	-	pathogenesis
HPEMBLHF_00775	2.25e-91	-	-	-	O	-	-	-	response to oxidative stress
HPEMBLHF_00776	1.16e-286	-	2.3.1.31	-	E	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko01000	alpha/beta hydrolase fold
HPEMBLHF_00777	3.6e-62	-	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L36
HPEMBLHF_00778	0.0	-	2.3.1.241	-	M	ko:K02517	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Glycosyltransferase family 9 (heptosyltransferase)
HPEMBLHF_00779	3.71e-189	-	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	4Fe-4S single cluster domain
HPEMBLHF_00780	0.0	-	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HPEMBLHF_00781	2.02e-22	-	-	-	S	-	-	-	COG NOG06097 non supervised orthologous group
HPEMBLHF_00782	1.2e-55	-	-	-	S	-	-	-	Glycosyl hydrolase family 115
HPEMBLHF_00783	1.27e-101	-	-	-	S	-	-	-	Glycosyl hydrolase family 115
HPEMBLHF_00784	1.42e-174	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
HPEMBLHF_00785	0.0	-	-	-	EG	-	-	-	BNR repeat-like domain
HPEMBLHF_00786	0.0	legA	3.5.1.2	-	G	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	response to abiotic stimulus
HPEMBLHF_00787	2.91e-199	supH	-	-	Q	-	-	-	phosphatase activity
HPEMBLHF_00789	5.49e-85	nuoA	1.6.5.3	-	C	ko:K00330	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPEMBLHF_00790	2.9e-275	-	-	-	G	-	-	-	Major Facilitator Superfamily
HPEMBLHF_00794	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HPEMBLHF_00795	2.91e-38	-	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
HPEMBLHF_00796	5.25e-79	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HPEMBLHF_00797	0.0	-	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	Peptidase family M50
HPEMBLHF_00800	0.0	-	-	-	L	-	-	-	UvrD/REP helicase N-terminal domain
HPEMBLHF_00801	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
HPEMBLHF_00802	5.94e-209	MA20_36650	-	-	EG	-	-	-	spore germination
HPEMBLHF_00803	0.0	-	-	-	S	-	-	-	Alpha-2-macroglobulin family
HPEMBLHF_00804	2.76e-194	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
HPEMBLHF_00806	1.96e-33	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
HPEMBLHF_00808	3.94e-121	-	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
HPEMBLHF_00811	4.04e-210	-	-	-	-	-	-	-	-
HPEMBLHF_00812	1.09e-149	-	-	-	O	-	-	-	Glycoprotease family
HPEMBLHF_00813	2.89e-272	-	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
HPEMBLHF_00814	2.35e-05	-	-	-	S	ko:K08984	-	ko00000	Predicted membrane protein (DUF2238)
HPEMBLHF_00815	1.57e-111	-	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HPEMBLHF_00816	1.18e-138	-	-	-	L	-	-	-	RNase_H superfamily
HPEMBLHF_00818	6.68e-103	smpB	-	-	O	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HPEMBLHF_00819	1.5e-44	-	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	RNA polymerase activity
HPEMBLHF_00820	1.43e-135	-	5.4.99.20	-	J	ko:K06181	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
HPEMBLHF_00821	4.74e-210	-	-	-	-	-	-	-	-
HPEMBLHF_00822	6.2e-103	-	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	NDK
HPEMBLHF_00823	4.9e-201	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HPEMBLHF_00824	4.12e-225	-	-	-	M	-	-	-	Glycosyl transferase family 2
HPEMBLHF_00825	3.51e-07	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
HPEMBLHF_00826	1.2e-283	-	-	-	NU	ko:K02653	-	ko00000,ko02035,ko02044	Type II secretion system (T2SS), protein F
HPEMBLHF_00827	0.0	-	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II secretion system (T2SS), protein E, N-terminal domain
HPEMBLHF_00828	0.0	-	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
HPEMBLHF_00829	2.97e-244	-	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HPEMBLHF_00830	2.83e-110	-	-	-	S	-	-	-	Control of competence regulator ComK, YlbF/YmcA
HPEMBLHF_00831	6.39e-280	-	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
HPEMBLHF_00832	0.0	murJ	-	-	S	ko:K03980	-	ko00000,ko01011,ko02000	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HPEMBLHF_00833	1.26e-271	-	-	-	IM	-	-	-	Cytidylyltransferase-like
HPEMBLHF_00834	1.74e-157	-	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Iron/manganese superoxide dismutases, alpha-hairpin domain
HPEMBLHF_00835	0.0	-	-	-	S	-	-	-	Glycosyl hydrolase-like 10
HPEMBLHF_00836	1.41e-164	-	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
HPEMBLHF_00837	9e-187	-	-	-	L	ko:K06864	-	ko00000	tRNA processing
HPEMBLHF_00838	2.65e-288	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HPEMBLHF_00839	1.07e-238	-	2.5.1.90	-	H	ko:K02523	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Polyprenyl synthetase
HPEMBLHF_00840	0.0	-	-	-	E	ko:K03305	-	ko00000	POT family
HPEMBLHF_00841	0.0	-	5.2.1.8	-	O	ko:K03770	-	ko00000,ko01000,ko03110	PPIC-type PPIASE domain
HPEMBLHF_00842	2.39e-126	-	-	-	S	-	-	-	Pfam:DUF59
HPEMBLHF_00843	2.59e-107	-	-	-	-	-	-	-	-
HPEMBLHF_00845	3.12e-219	-	-	-	E	-	-	-	Domain of unknown function (DUF3472)
HPEMBLHF_00846	9.04e-317	nuoN	1.6.5.3	-	C	ko:K00343	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPEMBLHF_00847	0.0	-	1.6.5.3	-	C	ko:K00342	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Proton-conducting membrane transporter
HPEMBLHF_00848	0.0	-	1.6.5.3	-	CP	ko:K00341	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus
HPEMBLHF_00849	6.01e-61	nuoK	1.6.5.3	-	C	ko:K00340	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPEMBLHF_00850	1.04e-154	-	1.6.5.3	-	C	ko:K00339	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone/plastoquinone oxidoreductase chain 6
HPEMBLHF_00851	1.8e-124	nuoI	1.6.5.3	-	C	ko:K00338	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPEMBLHF_00852	1.04e-309	nuoH	1.6.5.3	-	C	ko:K00337	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HPEMBLHF_00853	0.0	-	1.6.5.3	-	C	ko:K00336	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
HPEMBLHF_00854	0.0	-	1.6.5.3	-	C	ko:K00335	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
HPEMBLHF_00855	2.88e-142	-	1.6.5.3	-	C	ko:K00334	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Thioredoxin-like [2Fe-2S] ferredoxin
HPEMBLHF_00856	4.39e-307	nuoD	1.6.5.3	-	C	ko:K00333	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPEMBLHF_00858	0.0	-	-	-	G	-	-	-	Polysaccharide deacetylase
HPEMBLHF_00859	0.0	-	-	-	P	-	-	-	Putative Na+/H+ antiporter
HPEMBLHF_00860	3.59e-140	-	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Lumazine binding domain
HPEMBLHF_00861	6.66e-201	-	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
HPEMBLHF_00862	0.0	pmp21	-	-	T	-	-	-	pathogenesis
HPEMBLHF_00863	6.7e-114	pmp21	-	-	T	-	-	-	pathogenesis
HPEMBLHF_00864	0.0	-	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
HPEMBLHF_00866	0.0	-	2.8.4.4	-	J	ko:K14441	-	ko00000,ko01000,ko03009	Uncharacterized protein family UPF0004
HPEMBLHF_00867	0.0	-	-	-	-	ko:K07403	-	ko00000	-
HPEMBLHF_00868	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HPEMBLHF_00869	0.0	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HPEMBLHF_00870	2.94e-184	-	3.4.13.22	-	M	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-ala-D-ala dipeptidase
HPEMBLHF_00873	0.0	-	-	-	E	-	-	-	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HPEMBLHF_00874	0.0	-	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	tail specific protease
HPEMBLHF_00875	5.43e-214	-	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
HPEMBLHF_00876	0.0	-	3.6.4.13	-	L	ko:K03579	-	ko00000,ko01000	ATP-dependent helicase C-terminal
HPEMBLHF_00877	0.0	-	-	-	P	ko:K03306	-	ko00000	phosphate transporter
HPEMBLHF_00878	4.13e-312	-	-	-	O	-	-	-	peroxiredoxin activity
HPEMBLHF_00879	0.0	-	2.7.7.19	-	J	ko:K00970	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Poly A polymerase head domain
HPEMBLHF_00880	0.0	-	-	-	G	-	-	-	Alpha amylase, catalytic domain
HPEMBLHF_00881	0.0	-	-	-	NU	ko:K02453	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Bacterial type II and III secretion system protein
HPEMBLHF_00882	0.0	-	-	-	-	-	-	-	-
HPEMBLHF_00883	7.21e-183	-	-	-	S	ko:K09778	-	ko00000	Domain of unknown function (DUF374)
HPEMBLHF_00884	7.21e-203	folD	1.5.1.5, 3.5.4.9	-	H	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HPEMBLHF_00885	2.91e-182	-	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HPEMBLHF_00886	6.43e-203	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HPEMBLHF_00887	1.9e-281	-	-	-	E	-	-	-	Transglutaminase-like superfamily
HPEMBLHF_00888	8.33e-259	-	-	-	J	ko:K05541	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HPEMBLHF_00889	1.87e-289	-	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	LytB protein
HPEMBLHF_00891	9.53e-43	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S20
HPEMBLHF_00892	6.98e-143	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HPEMBLHF_00893	0.0	-	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
HPEMBLHF_00896	3.25e-223	-	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Phosphatidylserine decarboxylase
HPEMBLHF_00897	9.06e-151	-	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3 epimerase family
HPEMBLHF_00898	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Leucyl-tRNA synthetase, Domain 2
HPEMBLHF_00899	0.0	-	-	-	P	-	-	-	Sulfatase
HPEMBLHF_00901	7.45e-301	-	4.1.1.96	-	E	ko:K13747	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Pyridoxal-dependent decarboxylase, C-terminal sheet domain
HPEMBLHF_00902	0.0	-	4.1.1.19	-	E	ko:K01585	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase, pyridoxal binding domain
HPEMBLHF_00903	3.2e-266	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPEMBLHF_00904	3.22e-184	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HPEMBLHF_00905	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Beta galactosidase small chain
HPEMBLHF_00906	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
HPEMBLHF_00907	0.0	rarA	-	-	L	ko:K07478	-	ko00000	MgsA AAA+ ATPase C terminal
HPEMBLHF_00908	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	PFAM Glycoside hydrolase, family 20, catalytic core
HPEMBLHF_00910	2.5e-297	-	2.7.1.11, 2.7.1.90	-	H	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
HPEMBLHF_00911	2.22e-132	-	-	-	M	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
HPEMBLHF_00913	7.64e-155	-	-	-	C	ko:K06871	-	ko00000	4Fe-4S single cluster domain
HPEMBLHF_00915	8.87e-269	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
HPEMBLHF_00919	1.28e-126	cobU	2.7.1.156, 2.7.7.62, 6.3.5.10	-	H	ko:K02231,ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	cobinamide kinase activity
HPEMBLHF_00920	1.16e-207	-	-	-	G	-	-	-	myo-inosose-2 dehydratase activity
HPEMBLHF_00921	1.55e-170	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HPEMBLHF_00922	2.08e-241	cobT	2.4.2.21	-	H	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HPEMBLHF_00923	1.06e-235	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HPEMBLHF_00924	0.0	cobQ	-	-	H	-	-	-	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HPEMBLHF_00926	0.0	-	-	-	H	ko:K02014	-	ko00000,ko02000	TonB dependent receptor
HPEMBLHF_00928	0.0	-	-	-	E	ko:K13893	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HPEMBLHF_00929	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
HPEMBLHF_00930	1.91e-159	-	-	-	M	ko:K16079	-	ko00000,ko02000	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HPEMBLHF_00931	7.01e-308	-	3.5.4.28, 3.5.4.31	-	F	ko:K12960	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
HPEMBLHF_00932	0.0	-	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HPEMBLHF_00933	1.94e-114	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HPEMBLHF_00934	3.15e-224	-	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
HPEMBLHF_00935	0.0	-	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoglutarate dehydrogenase C-terminal
HPEMBLHF_00936	1.65e-242	-	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit II
HPEMBLHF_00937	0.0	-	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit I
HPEMBLHF_00938	2.7e-113	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HPEMBLHF_00939	2.34e-107	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
HPEMBLHF_00940	0.0	-	-	-	T	-	-	-	Chase2 domain
HPEMBLHF_00941	3.05e-235	-	2.7.1.221	-	S	ko:K07102	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Phosphotransferase enzyme family
HPEMBLHF_00942	2.95e-306	-	4.2.1.20	-	E	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HPEMBLHF_00943	4.98e-92	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HPEMBLHF_00944	1.23e-112	-	1.16.3.2	-	P	ko:K02217	-	ko00000,ko01000	Ferritin-like domain
HPEMBLHF_00945	0.0	-	-	-	-	-	-	-	-
HPEMBLHF_00946	1.28e-102	-	-	-	J	-	-	-	YjgF/chorismate_mutase-like, putative endoribonuclease
HPEMBLHF_00948	5.93e-156	-	-	-	S	ko:K03748	-	ko00000	DUF218 domain
HPEMBLHF_00950	3.4e-231	-	-	-	S	-	-	-	mannose-ethanolamine phosphotransferase activity
HPEMBLHF_00956	0.0	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RQC
HPEMBLHF_00958	4.71e-175	-	-	-	-	-	-	-	-
HPEMBLHF_00959	3.89e-209	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HPEMBLHF_00960	2.55e-268	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HPEMBLHF_00961	5.4e-292	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HPEMBLHF_00962	2.43e-209	-	-	-	S	ko:K03453	-	ko00000	Bile acid
HPEMBLHF_00967	6.39e-71	-	-	-	-	-	-	-	-
HPEMBLHF_00968	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HPEMBLHF_00969	0.0	-	2.3.1.40, 6.2.1.20	-	IQ	ko:K05939	ko00071,ko00564,map00071,map00564	ko00000,ko00001,ko01000	AMP-binding enzyme
HPEMBLHF_00970	2.26e-38	-	-	-	T	-	-	-	pathogenesis
HPEMBLHF_00976	1.53e-122	-	-	-	L	ko:K07480	-	ko00000	Absolutely required for transposition of IS1
HPEMBLHF_00977	4.13e-67	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
HPEMBLHF_00979	5.22e-193	-	-	-	U	-	-	-	Passenger-associated-transport-repeat
HPEMBLHF_00989	0.0	-	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HPEMBLHF_00990	1.6e-128	-	-	-	D	ko:K06287	-	ko00000	Maf-like protein
HPEMBLHF_00991	3.78e-290	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HPEMBLHF_00993	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HPEMBLHF_00994	0.0	-	-	-	GK	-	-	-	carbohydrate kinase activity
HPEMBLHF_00995	3.57e-201	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HPEMBLHF_00996	1.16e-207	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HPEMBLHF_00997	0.0	-	-	-	I	-	-	-	Acetyltransferase (GNAT) domain
HPEMBLHF_00998	3.27e-142	-	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Cytidylate kinase
HPEMBLHF_00999	1.36e-145	-	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HPEMBLHF_01000	1.06e-257	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HPEMBLHF_01001	3.75e-121	actI	1.5.1.36	-	S	ko:K00484	ko00350,ko00740,ko01100,ko01120,ko01220,map00350,map00740,map01100,map01120,map01220	ko00000,ko00001,ko01000	FMN binding
HPEMBLHF_01002	2.6e-160	rnc	3.1.26.3	-	K	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HPEMBLHF_01003	0.0	-	-	-	P	ko:K07221	-	ko00000,ko02000	Phosphate-selective porin O and P
HPEMBLHF_01004	2.72e-18	-	-	-	-	-	-	-	-
HPEMBLHF_01005	5.13e-179	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
HPEMBLHF_01006	4.83e-163	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Tetrapyrrole (Corrin/Porphyrin) Methylases
HPEMBLHF_01007	7.51e-116	-	-	-	S	-	-	-	Lipopolysaccharide-assembly
HPEMBLHF_01008	1.18e-170	-	-	-	S	ko:K05807	-	ko00000,ko02000	Outer membrane lipoprotein
HPEMBLHF_01009	2.03e-116	hisI	3.5.4.19	-	E	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-AMP cyclohydrolase
HPEMBLHF_01010	3.12e-224	-	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, delta subunit
HPEMBLHF_01011	3.45e-121	-	3.2.2.28	-	L	ko:K03649	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	G/U mismatch-specific uracil-DNA glycosylase activity
HPEMBLHF_01012	1.99e-193	-	-	-	-	-	-	-	-
HPEMBLHF_01013	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HPEMBLHF_01014	1.41e-152	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Serine/threonine phosphatases, family 2C, catalytic domain
HPEMBLHF_01015	1.25e-109	-	-	-	Q	-	-	-	methyltransferase activity
HPEMBLHF_01016	2.7e-46	-	-	-	Q	-	-	-	methyltransferase activity
HPEMBLHF_01017	0.0	-	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	NAD synthase
HPEMBLHF_01018	2.28e-79	-	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
HPEMBLHF_01019	4.41e-311	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR/Asp-box repeat
HPEMBLHF_01020	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
HPEMBLHF_01021	4.48e-304	-	-	-	L	-	-	-	AAA ATPase domain
HPEMBLHF_01023	4.39e-244	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HPEMBLHF_01024	6.41e-237	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HPEMBLHF_01025	4.5e-283	-	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HPEMBLHF_01026	2.11e-206	MA20_42350	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyl transferase, family 2
HPEMBLHF_01027	3.11e-247	-	-	-	M	-	-	-	Glycosyl transferase, family 2
HPEMBLHF_01028	2.83e-237	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
HPEMBLHF_01030	0.0	-	-	-	S	-	-	-	polysaccharide biosynthetic process
HPEMBLHF_01031	1.54e-277	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HPEMBLHF_01032	1.76e-278	-	-	-	M	-	-	-	Glycosyl transferases group 1
HPEMBLHF_01033	3.73e-144	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
HPEMBLHF_01034	3.93e-223	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
HPEMBLHF_01035	3.69e-178	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HPEMBLHF_01036	1.47e-208	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HPEMBLHF_01037	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase activity
HPEMBLHF_01038	3.05e-260	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HPEMBLHF_01039	2.58e-310	mnmE	-	-	J	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HPEMBLHF_01040	1.05e-161	-	-	-	L	-	-	-	DNA binding domain, excisionase family
HPEMBLHF_01041	8.4e-259	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPEMBLHF_01042	6.24e-66	-	-	-	S	-	-	-	COG3943, virulence protein
HPEMBLHF_01043	1.69e-139	-	-	-	S	-	-	-	Mobilizable transposon, TnpC family protein
HPEMBLHF_01044	4.65e-83	-	-	-	-	-	-	-	-
HPEMBLHF_01045	1.12e-75	-	-	-	K	-	-	-	DNA binding domain, excisionase family
HPEMBLHF_01046	3.01e-309	-	-	-	S	-	-	-	Protein of unknown function (DUF3987)
HPEMBLHF_01047	1.53e-245	-	-	-	L	-	-	-	COG NOG08810 non supervised orthologous group
HPEMBLHF_01048	9.73e-52	-	-	-	S	-	-	-	Bacterial mobilization protein MobC
HPEMBLHF_01049	2.83e-195	-	-	-	U	-	-	-	Relaxase mobilization nuclease domain protein
HPEMBLHF_01050	3.89e-84	-	-	-	-	-	-	-	-
HPEMBLHF_01051	9.3e-125	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HPEMBLHF_01052	2.15e-205	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
HPEMBLHF_01053	0.0	-	-	-	L	-	-	-	helicase
HPEMBLHF_01054	0.0	-	-	-	L	-	-	-	COG1002 Type II restriction enzyme methylase subunits
HPEMBLHF_01055	7.56e-144	-	-	-	L	-	-	-	COG1002 Type II restriction enzyme methylase subunits
HPEMBLHF_01056	1.36e-120	-	-	-	L	-	-	-	COG COG1961 Site-specific recombinases, DNA invertase Pin homologs
HPEMBLHF_01057	9.74e-94	-	-	-	S	-	-	-	Domain in cystathionine beta-synthase and other proteins.
HPEMBLHF_01058	5.41e-145	-	-	-	S	-	-	-	UPF0126 domain
HPEMBLHF_01059	3.28e-187	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HPEMBLHF_01060	4.54e-105	-	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HPEMBLHF_01061	0.0	rsmH	2.1.1.199	-	M	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HPEMBLHF_01063	0.0	-	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding Protein dimerisation domain
HPEMBLHF_01064	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HPEMBLHF_01065	0.0	-	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Mur ligase middle domain
HPEMBLHF_01066	1.1e-258	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HPEMBLHF_01067	1.57e-306	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HPEMBLHF_01068	1.93e-158	mltD	-	CBM50	M	ko:K08307,ko:K12204,ko:K19224	-	ko00000,ko01000,ko01002,ko01011,ko02044	LysM domain
HPEMBLHF_01069	7.71e-277	-	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Cell cycle protein
HPEMBLHF_01070	3.74e-265	-	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HPEMBLHF_01071	0.0	murB	-	-	M	-	-	-	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
HPEMBLHF_01072	2.79e-226	ddl	6.3.2.4	-	M	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	D-ala D-ala ligase N-terminus
HPEMBLHF_01073	2.55e-216	-	-	-	M	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	POTRA domain, FtsQ-type
HPEMBLHF_01074	1.15e-238	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HPEMBLHF_01075	1.92e-238	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
HPEMBLHF_01076	1.68e-139	-	2.3.1.181	-	H	ko:K03801	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
HPEMBLHF_01077	0.0	-	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase family (aconitate hydratase)
HPEMBLHF_01078	4.38e-146	-	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase C-terminal domain
HPEMBLHF_01079	2.89e-273	-	-	-	-	-	-	-	-
HPEMBLHF_01080	0.0	-	-	-	O	-	-	-	Trypsin
HPEMBLHF_01081	0.0	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HPEMBLHF_01082	6.16e-282	-	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	3-dehydroquinate synthase
HPEMBLHF_01084	5.35e-174	-	-	-	E	-	-	-	ATPases associated with a variety of cellular activities
HPEMBLHF_01085	2.05e-198	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HPEMBLHF_01086	5.88e-163	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S2
HPEMBLHF_01087	2.03e-175	cbiX	4.99.1.3	-	S	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	sirohydrochlorin cobaltochelatase activity
HPEMBLHF_01088	1.64e-198	-	2.5.1.55	-	M	ko:K01627	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	DAHP synthetase I family
HPEMBLHF_01091	5.19e-170	-	-	-	S	ko:K06861	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HPEMBLHF_01092	3.12e-219	-	-	-	E	-	-	-	Phosphoserine phosphatase
HPEMBLHF_01093	0.0	-	6.3.2.45	-	M	ko:K02558	-	ko00000,ko01000	Mur ligase family, catalytic domain
HPEMBLHF_01094	4.42e-306	-	-	-	M	-	-	-	OmpA family
HPEMBLHF_01095	0.0	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD-like helicase C-terminal domain
HPEMBLHF_01096	4.59e-86	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HPEMBLHF_01097	1.31e-114	ywrF	-	-	S	-	-	-	FMN binding
HPEMBLHF_01098	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HPEMBLHF_01102	4.61e-67	-	-	-	M	-	-	-	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HPEMBLHF_01103	6.39e-224	-	-	-	L	-	-	-	Transposase zinc-ribbon domain
HPEMBLHF_01104	0.0	-	-	-	T	-	-	-	pathogenesis
HPEMBLHF_01106	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class II (D, K and N)
HPEMBLHF_01107	1.22e-310	-	-	-	-	-	-	-	-
HPEMBLHF_01108	5.12e-71	-	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
HPEMBLHF_01110	5.24e-159	-	-	-	S	-	-	-	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HPEMBLHF_01111	9.82e-262	-	-	-	M	ko:K02022	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPEMBLHF_01112	1.7e-301	-	4.2.1.129, 5.4.99.17, 5.5.1.16	-	I	ko:K06045,ko:K17811	ko00909,ko01110,map00909,map01110	ko00000,ko00001,ko01000	PFAM Prenyltransferase squalene oxidase
HPEMBLHF_01113	2.99e-316	-	-	-	I	-	-	-	PFAM Prenyltransferase squalene oxidase
HPEMBLHF_01114	1.38e-276	-	3.2.1.23	-	M	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HPEMBLHF_01117	2.21e-215	-	-	-	K	-	-	-	LysR substrate binding domain
HPEMBLHF_01118	9.03e-233	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HPEMBLHF_01119	7.38e-252	-	-	-	E	-	-	-	Aminotransferase class-V
HPEMBLHF_01120	2.2e-313	-	-	-	S	-	-	-	Protein of unknown function (DUF1015)
HPEMBLHF_01121	0.0	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HPEMBLHF_01122	1.8e-179	-	2.7.13.3	-	Q	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Transposase
HPEMBLHF_01123	9.46e-167	-	4.3.99.3	-	O	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HPEMBLHF_01124	0.0	-	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HPEMBLHF_01125	5.84e-173	-	-	-	K	-	-	-	Transcriptional regulator
HPEMBLHF_01126	0.0	-	-	-	P	-	-	-	Dimerisation domain of Zinc Transporter
HPEMBLHF_01127	0.0	-	-	-	P	ko:K03455	-	ko00000	TrkA-N domain
HPEMBLHF_01129	1.36e-242	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HPEMBLHF_01130	1.79e-201	-	-	-	S	-	-	-	SigmaW regulon antibacterial
HPEMBLHF_01132	1.99e-172	-	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiazole biosynthesis protein ThiG
HPEMBLHF_01133	2.17e-291	-	-	-	E	-	-	-	Amino acid permease
HPEMBLHF_01134	1.39e-156	gph	3.1.3.18, 3.6.1.1	-	S	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	glycolate biosynthetic process
HPEMBLHF_01135	6.62e-257	-	-	-	S	ko:K11744	-	ko00000	AI-2E family transporter
HPEMBLHF_01136	7.68e-311	-	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase, pyridoxal binding domain
HPEMBLHF_01137	1.32e-235	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HPEMBLHF_01138	0.0	-	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
HPEMBLHF_01139	2.02e-212	-	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HPEMBLHF_01140	8.82e-221	-	-	-	G	-	-	-	Glycosyl hydrolases family 16
HPEMBLHF_01141	1.62e-129	-	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HPEMBLHF_01142	1.78e-134	-	-	-	T	-	-	-	histone H2A K63-linked ubiquitination
HPEMBLHF_01144	1.87e-252	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HPEMBLHF_01145	1.16e-285	-	-	-	S	-	-	-	Phosphotransferase enzyme family
HPEMBLHF_01146	1.55e-254	-	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HPEMBLHF_01147	2.16e-268	-	-	GT4	M	ko:K16703	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
HPEMBLHF_01149	1.22e-27	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HPEMBLHF_01150	3.51e-13	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HPEMBLHF_01152	0.0	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HPEMBLHF_01153	4.84e-117	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
HPEMBLHF_01154	0.0	-	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase / GMP reductase domain
HPEMBLHF_01155	0.0	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	GMP synthase C terminal domain
HPEMBLHF_01156	2.22e-283	-	-	-	D	-	-	-	nuclear chromosome segregation
HPEMBLHF_01157	3.07e-136	-	-	-	S	-	-	-	Maltose acetyltransferase
HPEMBLHF_01158	6.92e-148	ppaX_1	3.1.3.18, 3.6.1.1	-	S	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	glycolate biosynthetic process
HPEMBLHF_01159	3.52e-59	-	-	-	S	-	-	-	NYN domain
HPEMBLHF_01160	1.02e-232	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HPEMBLHF_01161	1.06e-127	-	-	-	-	-	-	-	-
HPEMBLHF_01162	6.87e-256	-	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HPEMBLHF_01163	1.15e-151	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
HPEMBLHF_01164	2.82e-87	-	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
HPEMBLHF_01165	1.49e-63	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HPEMBLHF_01166	4.08e-219	-	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin kinase
HPEMBLHF_01167	9.36e-171	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HPEMBLHF_01168	4.91e-240	-	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
HPEMBLHF_01170	1.03e-207	lpxG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
HPEMBLHF_01171	1.85e-243	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
HPEMBLHF_01172	6.51e-247	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HPEMBLHF_01173	1.11e-234	-	-	GT9	M	ko:K02843,ko:K02849	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	ADP-heptose-lipopolysaccharide heptosyltransferase activity
HPEMBLHF_01174	1.31e-244	-	5.1.3.20	-	M	ko:K03274	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	3-beta hydroxysteroid dehydrogenase/isomerase family
HPEMBLHF_01176	4.35e-285	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HPEMBLHF_01177	8.99e-202	-	-	-	-	-	-	-	-
HPEMBLHF_01178	4.73e-304	-	-	-	M	-	-	-	Glycosyl transferases group 1
HPEMBLHF_01179	1.43e-250	-	-	-	S	-	-	-	Glycosyltransferase family 10 (fucosyltransferase) C-term
HPEMBLHF_01180	0.0	-	-	-	I	-	-	-	Acyltransferase family
HPEMBLHF_01181	1.62e-257	-	-	-	S	-	-	-	Glycosyltransferase family 10 (fucosyltransferase) C-term
HPEMBLHF_01183	0.0	-	-	-	P	-	-	-	Citrate transporter
HPEMBLHF_01185	3.12e-110	-	-	-	S	ko:K08999	-	ko00000	Bifunctional nuclease
HPEMBLHF_01186	5.58e-110	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
HPEMBLHF_01187	0.0	-	-	-	E	-	-	-	Transglutaminase-like
HPEMBLHF_01188	8.77e-158	-	-	-	C	-	-	-	Nitroreductase family
HPEMBLHF_01189	0.0	-	3.2.1.23	-	G	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
HPEMBLHF_01190	4.57e-181	-	-	-	CH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HPEMBLHF_01191	1.69e-242	-	-	-	CH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HPEMBLHF_01192	1.41e-289	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HPEMBLHF_01193	8.86e-317	hsrA	-	-	EGP	-	-	-	Major facilitator Superfamily
HPEMBLHF_01194	7.17e-104	yciA	-	-	I	ko:K10806	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	acyl-coa hydrolase
HPEMBLHF_01197	5.98e-205	-	-	-	IQ	-	-	-	KR domain
HPEMBLHF_01198	7.35e-243	-	-	-	M	-	-	-	Alginate lyase
HPEMBLHF_01199	2.25e-116	-	-	-	L	-	-	-	Staphylococcal nuclease homologues
HPEMBLHF_01202	2e-120	-	-	-	K	-	-	-	ParB domain protein nuclease
HPEMBLHF_01203	0.0	-	-	-	S	-	-	-	Phosphoadenosine phosphosulfate reductase
HPEMBLHF_01206	2.64e-267	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HPEMBLHF_01207	1.35e-39	-	-	-	E	-	-	-	FAD dependent oxidoreductase
HPEMBLHF_01208	5.82e-216	-	-	-	E	-	-	-	FAD dependent oxidoreductase
HPEMBLHF_01209	1.21e-210	-	-	-	S	-	-	-	Rhomboid family
HPEMBLHF_01210	0.0	-	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
HPEMBLHF_01211	8.03e-05	-	-	-	-	-	-	-	-
HPEMBLHF_01212	9.6e-317	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
HPEMBLHF_01213	1.32e-313	pqqE	-	-	C	ko:K06139	-	ko00000	SMART Elongator protein 3 MiaB NifB
HPEMBLHF_01214	9.87e-264	pqqE	-	-	C	ko:K06139	-	ko00000	SMART Elongator protein 3 MiaB NifB
HPEMBLHF_01216	4.11e-100	-	-	-	-	-	-	-	-
HPEMBLHF_01217	8.08e-236	gpsA	1.1.1.94	-	C	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
HPEMBLHF_01218	4.34e-152	-	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Glycerol-3-phosphate acyltransferase
HPEMBLHF_01219	1.02e-187	pppL	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	protein serine/threonine phosphatase activity
HPEMBLHF_01220	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class II (D, K and N)
HPEMBLHF_01221	0.0	-	1.2.7.1	-	C	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HPEMBLHF_01222	2.19e-100	manC	-	-	S	-	-	-	Cupin domain
HPEMBLHF_01223	3.2e-70	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HPEMBLHF_01224	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF4091)
HPEMBLHF_01225	8.64e-177	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HPEMBLHF_01227	0.0	-	-	-	P	-	-	-	Cation transport protein
HPEMBLHF_01228	3.52e-161	-	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
HPEMBLHF_01229	0.0	-	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Oligonucleotide/oligosaccharide-binding (OB)-fold
HPEMBLHF_01230	7.97e-108	-	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
HPEMBLHF_01231	0.0	-	-	-	O	-	-	-	Trypsin
HPEMBLHF_01232	7.08e-272	-	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, delta subunit
HPEMBLHF_01233	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HPEMBLHF_01234	7.22e-263	-	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	RibD C-terminal domain
HPEMBLHF_01235	1.02e-258	-	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HPEMBLHF_01237	3.23e-247	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	adenosylhomocysteinase activity
HPEMBLHF_01238	4.54e-95	-	-	-	V	-	-	-	MatE
HPEMBLHF_01239	1.8e-184	-	-	-	V	-	-	-	MatE
HPEMBLHF_01240	2.41e-177	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HPEMBLHF_01241	2.63e-84	-	-	-	M	-	-	-	Lysin motif
HPEMBLHF_01242	1.78e-202	-	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
HPEMBLHF_01243	5.87e-265	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2219)
HPEMBLHF_01244	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Beta galactosidase small chain
HPEMBLHF_01245	2.66e-06	-	-	-	-	-	-	-	-
HPEMBLHF_01247	0.0	-	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Osmosensitive K+ channel His kinase sensor domain
HPEMBLHF_01248	2.4e-167	-	-	-	T	ko:K07667	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HPEMBLHF_01250	0.0	-	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HPEMBLHF_01251	0.0	-	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HPEMBLHF_01252	1.08e-127	-	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HPEMBLHF_01253	9.07e-73	-	-	-	S	-	-	-	PFAM Cupin 2 conserved barrel domain protein
HPEMBLHF_01254	5.23e-230	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HPEMBLHF_01255	0.0	-	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	C-terminal, D2-small domain, of ClpB protein
HPEMBLHF_01258	2.56e-71	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
HPEMBLHF_01259	0.0	-	4.2.1.2	-	C	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
HPEMBLHF_01260	3e-250	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
HPEMBLHF_01261	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HPEMBLHF_01265	1.7e-260	-	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HPEMBLHF_01266	1.4e-153	-	1.5.1.34	-	C	ko:K10679	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nitroreductase family
HPEMBLHF_01267	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, domain 2
HPEMBLHF_01268	7.19e-179	-	-	-	M	-	-	-	NLP P60 protein
HPEMBLHF_01269	1.37e-86	-	-	-	S	ko:K09940	-	ko00000	Domain of unknown function (DUF4870)
HPEMBLHF_01271	2.09e-76	-	-	-	C	ko:K04651	-	ko00000,ko03110	Hydrogenase/urease nickel incorporation, metallochaperone, hypA
HPEMBLHF_01272	3.4e-126	-	-	-	C	ko:K03605	-	ko00000,ko01000,ko01002	Hydrogenase maturation protease
HPEMBLHF_01273	1.12e-290	hyaC	-	-	C	ko:K03620	ko02020,map02020	ko00000,ko00001	Prokaryotic cytochrome b561
HPEMBLHF_01274	0.0	-	1.12.99.6	-	C	ko:K06281	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nickel-dependent hydrogenase
HPEMBLHF_01275	1.63e-296	-	1.12.99.6	-	C	ko:K06282	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	NiFe/NiFeSe hydrogenase small subunit C-terminal
HPEMBLHF_01276	0.0	-	-	-	M	ko:K07267	-	ko00000,ko02000	wide pore channel activity
HPEMBLHF_01278	1.28e-315	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HPEMBLHF_01279	0.0	-	-	-	H	-	-	-	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HPEMBLHF_01280	0.0	-	3.4.24.3	-	NU	ko:K01387	-	ko00000,ko01000,ko01002,ko02042	translation initiation factor activity
HPEMBLHF_01281	0.0	-	-	-	M	-	-	-	Transglycosylase
HPEMBLHF_01282	2.63e-135	-	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	Peptidyl-tRNA hydrolase
HPEMBLHF_01283	1.53e-213	-	-	-	S	-	-	-	Protein of unknown function DUF58
HPEMBLHF_01284	4.46e-230	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HPEMBLHF_01285	7.05e-216	-	3.5.1.53	-	K	ko:K12251	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HPEMBLHF_01287	5.79e-274	-	-	-	E	-	-	-	Alcohol dehydrogenase GroES-like domain
HPEMBLHF_01288	4.98e-310	-	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Seryl-tRNA synthetase N-terminal domain
HPEMBLHF_01290	1.47e-19	-	-	-	H	-	-	-	Elongator protein 3, MiaB family, Radical SAM
HPEMBLHF_01296	1.71e-263	-	-	-	H	-	-	-	Elongator protein 3, MiaB family, Radical SAM
HPEMBLHF_01297	0.0	yidC	-	-	O	ko:K03217,ko:K06872	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	serine-type endopeptidase activity
HPEMBLHF_01298	3.72e-158	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HPEMBLHF_01299	3.77e-127	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HPEMBLHF_01300	6.58e-253	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
HPEMBLHF_01301	8.66e-224	exsH	3.2.1.178, 3.2.1.18, 3.2.1.52	GH16,GH20,GH33	G	ko:K01186,ko:K12373,ko:K20830	ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko02042,ko03110	xyloglucan:xyloglucosyl transferase activity
HPEMBLHF_01302	0.0	-	-	-	I	ko:K06889,ko:K09914	-	ko00000	PFAM Prenyltransferase squalene oxidase
HPEMBLHF_01303	1.24e-315	-	1.1.1.40	-	C	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Malic enzyme, NAD binding domain
HPEMBLHF_01304	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HPEMBLHF_01305	0.0	-	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (C) catalytic domain
HPEMBLHF_01306	2.05e-298	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
HPEMBLHF_01307	1.19e-92	-	5.1.3.29	-	G	ko:K02431	-	ko00000,ko01000	RbsD / FucU transport protein family
HPEMBLHF_01308	5.07e-283	-	-	-	S	-	-	-	very-long-chain-acyl-CoA dehydrogenase activity
HPEMBLHF_01310	0.0	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HPEMBLHF_01311	6.02e-103	-	-	-	M	-	-	-	PFAM glycosyl transferase family 2
HPEMBLHF_01312	3.31e-39	-	-	-	I	-	-	-	Acyltransferase family
HPEMBLHF_01313	1.54e-66	-	-	-	S	ko:K03818	-	ko00000,ko01000	Bacterial transferase hexapeptide (six repeats)
HPEMBLHF_01314	1.35e-41	-	-	-	S	-	-	-	Glycosyl transferase family 2
HPEMBLHF_01315	7.06e-126	-	-	-	M	-	-	-	Glycosyl transferases group 1
HPEMBLHF_01316	4.18e-108	-	-	-	M	-	-	-	Glycosyl transferases group 1
HPEMBLHF_01318	4.26e-18	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
HPEMBLHF_01319	2.1e-116	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HPEMBLHF_01320	2.07e-153	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HPEMBLHF_01321	2.75e-120	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HPEMBLHF_01323	2.06e-35	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HPEMBLHF_01324	1.14e-63	-	-	-	H	-	-	-	Pfam:DUF1792
HPEMBLHF_01325	3.08e-40	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
HPEMBLHF_01326	8.38e-131	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HPEMBLHF_01327	1.03e-165	wbyL	-	GT2	M	ko:K13002	-	ko00000,ko01000,ko01003,ko01005	transferase activity, transferring glycosyl groups
HPEMBLHF_01328	3.97e-175	-	-	-	M	-	-	-	Bacterial sugar transferase
HPEMBLHF_01329	1.29e-162	-	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	protein tyrosine phosphatase activity
HPEMBLHF_01330	0.0	gumC	-	-	DM	ko:K16554	ko05111,map05111	ko00000,ko00001,ko02000	PFAM lipopolysaccharide biosynthesis protein
HPEMBLHF_01331	8.07e-180	-	-	-	M	ko:K01991	ko02026,map02026	ko00000,ko00001,ko02000	polysaccharide export
HPEMBLHF_01334	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	Ftsk_gamma
HPEMBLHF_01336	1.79e-143	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HPEMBLHF_01337	1.08e-136	rbr	-	-	C	-	-	-	Rubrerythrin
HPEMBLHF_01338	0.0	-	-	-	O	-	-	-	Cytochrome C assembly protein
HPEMBLHF_01340	0.0	-	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Catalase
HPEMBLHF_01341	1.01e-45	-	-	-	S	-	-	-	R3H domain
HPEMBLHF_01343	0.0	-	1.2.1.88, 1.5.5.2	-	CE	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko03000	Proline dehydrogenase
HPEMBLHF_01344	4.36e-282	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
HPEMBLHF_01345	6.06e-118	-	-	-	L	ko:K19118	-	ko00000,ko02048	CRISPR-associated protein Cas7
HPEMBLHF_01346	7.55e-161	-	-	-	S	ko:K19117	-	ko00000,ko02048	TIGRFAM CRISPR-associated protein
HPEMBLHF_01347	1.5e-69	-	-	-	S	ko:K19119	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
HPEMBLHF_01348	1.84e-156	-	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	helicase Cas3
HPEMBLHF_01349	3.07e-37	-	3.1.12.1	-	L	ko:K07464	-	ko00000,ko01000,ko02048	CRISPR-associated protein Cas4
HPEMBLHF_01350	1.73e-140	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HPEMBLHF_01351	2.31e-36	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HPEMBLHF_01353	6.96e-64	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HPEMBLHF_01354	3.45e-145	-	-	-	-	-	-	-	-
HPEMBLHF_01356	0.0	-	-	-	S	-	-	-	Bacteriophage head to tail connecting protein
HPEMBLHF_01358	1.01e-178	-	-	-	-	-	-	-	-
HPEMBLHF_01360	1.86e-114	-	-	-	CO	-	-	-	cell redox homeostasis
HPEMBLHF_01361	3.54e-75	-	-	-	S	-	-	-	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HPEMBLHF_01362	2.54e-73	-	-	-	S	-	-	-	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HPEMBLHF_01363	1.77e-114	-	-	-	S	-	-	-	nitrogen fixation
HPEMBLHF_01364	3.89e-149	dedA	-	-	S	-	-	-	FtsZ-dependent cytokinesis
HPEMBLHF_01365	5.95e-263	-	2.4.1.182	GT19	M	ko:K00748	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HPEMBLHF_01366	0.0	-	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
HPEMBLHF_01368	6.81e-251	-	-	-	L	-	-	-	Transposase IS200 like
HPEMBLHF_01369	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
HPEMBLHF_01370	1.34e-109	ptsN	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
HPEMBLHF_01373	1.59e-150	-	-	-	-	-	-	-	-
HPEMBLHF_01374	0.0	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HPEMBLHF_01376	0.0	-	-	-	MU	ko:K18139	ko01501,ko02024,map01501,map02024	ko00000,ko00001,ko00002,ko01504,ko02000	Outer membrane efflux protein
HPEMBLHF_01377	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HPEMBLHF_01378	1.38e-276	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPEMBLHF_01379	0.0	prlC	3.4.24.70	-	E	ko:K01414	-	ko00000,ko01000,ko01002	Peptidase family M3
HPEMBLHF_01380	0.0	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	LeuA allosteric (dimerisation) domain
HPEMBLHF_01381	6.78e-42	-	-	-	S	-	-	-	PurA ssDNA and RNA-binding protein
HPEMBLHF_01382	2.04e-254	-	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Iron-sulfur cluster assembly protein
HPEMBLHF_01383	0.0	-	-	-	V	ko:K03327	-	ko00000,ko02000	MatE
HPEMBLHF_01385	0.0	-	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	HMGL-like
HPEMBLHF_01386	0.0	-	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phospholipase D. Active site motifs.
HPEMBLHF_01387	1.65e-207	-	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Thymidylate synthase
HPEMBLHF_01388	4.82e-113	-	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Dihydrofolate reductase
HPEMBLHF_01389	0.0	-	-	-	V	-	-	-	AcrB/AcrD/AcrF family
HPEMBLHF_01390	4.9e-263	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Biotin-lipoyl like
HPEMBLHF_01391	1.69e-107	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HPEMBLHF_01393	2.53e-240	-	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase
HPEMBLHF_01394	3.89e-157	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HPEMBLHF_01395	1e-289	-	-	-	L	-	-	-	helicase superfamily c-terminal domain
HPEMBLHF_01396	3.46e-110	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HPEMBLHF_01397	1.06e-116	-	-	-	-	-	-	-	-
HPEMBLHF_01398	0.0	sepA	-	-	Q	-	-	-	COG2015, Alkyl sulfatase and related hydrolases
HPEMBLHF_01399	6.11e-111	-	-	-	F	ko:K08311	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	NUDIX domain
HPEMBLHF_01400	1.21e-241	-	-	-	E	ko:K07588	-	ko00000,ko01000	ArgK protein
HPEMBLHF_01401	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
HPEMBLHF_01402	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
HPEMBLHF_01404	4.27e-117	gepA	-	-	K	-	-	-	Phage-associated protein
HPEMBLHF_01405	1.15e-173	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HPEMBLHF_01406	2.41e-135	thiE	2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17	-	H	ko:K00788,ko:K03147,ko:K14153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HPEMBLHF_01407	1.07e-213	-	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HPEMBLHF_01408	1.37e-308	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
HPEMBLHF_01409	4.23e-99	-	-	-	K	-	-	-	Transcriptional regulator
HPEMBLHF_01410	4.05e-266	-	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HPEMBLHF_01411	4.41e-248	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPEMBLHF_01414	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Hsp90 protein
HPEMBLHF_01415	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
HPEMBLHF_01416	5.22e-265	-	-	-	P	ko:K03449	-	ko00000,ko02000	Major Facilitator Superfamily
HPEMBLHF_01417	1.16e-240	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Aminoacyl tRNA synthetase class II, N-terminal domain
HPEMBLHF_01418	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	B3/4 domain
HPEMBLHF_01419	2.45e-246	-	-	-	S	-	-	-	Domain of unknown function (DUF4105)
HPEMBLHF_01420	1.66e-143	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
HPEMBLHF_01421	0.0	-	4.1.99.1	-	E	ko:K01667	ko00380,map00380	ko00000,ko00001,ko01000	Beta-eliminating lyase
HPEMBLHF_01422	2.01e-34	-	-	-	KLT	-	-	-	Tyrosine-protein kinase, subgroup, catalytic domain
HPEMBLHF_01423	6.59e-227	-	-	-	S	-	-	-	Protein conserved in bacteria
HPEMBLHF_01424	2.24e-210	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
HPEMBLHF_01425	5.47e-158	-	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
HPEMBLHF_01426	1.22e-178	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Pyrroline-5-carboxylate reductase dimerisation
HPEMBLHF_01429	6.75e-245	-	-	-	I	-	-	-	PFAM Prenyltransferase squalene oxidase
HPEMBLHF_01430	2.25e-119	-	-	-	-	-	-	-	-
HPEMBLHF_01431	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
HPEMBLHF_01432	0.0	-	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Methylmalonyl-CoA mutase
HPEMBLHF_01433	0.0	-	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Methylmalonyl-CoA mutase
HPEMBLHF_01435	4.01e-219	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HPEMBLHF_01436	2.29e-253	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
HPEMBLHF_01437	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglucose isomerase
HPEMBLHF_01438	0.0	-	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Pyruvate phosphate dikinase, PEP/pyruvate binding domain
HPEMBLHF_01439	1e-142	aat	2.3.2.6	-	O	ko:K00684	-	ko00000,ko01000	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HPEMBLHF_01440	3.66e-253	-	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	endonuclease III
HPEMBLHF_01441	2.85e-214	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HPEMBLHF_01443	0.0	-	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
HPEMBLHF_01445	6.41e-180	-	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
HPEMBLHF_01446	3.2e-116	agmK	1.8.1.8	-	O	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko03110	belongs to the thioredoxin family
HPEMBLHF_01447	2.81e-278	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HPEMBLHF_01448	0.0	-	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HPEMBLHF_01450	1.35e-107	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HPEMBLHF_01451	2.75e-170	-	-	-	S	-	-	-	Putative threonine/serine exporter
HPEMBLHF_01452	0.0	-	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	B12 binding domain
HPEMBLHF_01455	2e-143	-	-	-	Q	-	-	-	PA14
HPEMBLHF_01457	2.25e-95	-	-	-	-	-	-	-	-
HPEMBLHF_01458	9.3e-278	mmyX	5.3.1.12	-	F	ko:K01812,ko:K07149,ko:K16139	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location Cytoplasmic, score
HPEMBLHF_01459	3.09e-107	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Cys-tRNA(Pro) hydrolase activity
HPEMBLHF_01462	6.8e-115	-	-	-	T	ko:K07005	-	ko00000	pyridoxamine 5'-phosphate
HPEMBLHF_01463	3.53e-134	-	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
HPEMBLHF_01464	1.87e-262	-	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
HPEMBLHF_01465	1.85e-144	-	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
HPEMBLHF_01466	2.74e-242	pabB	2.6.1.85, 4.1.3.27, 4.1.3.38	-	EH	ko:K01665,ko:K03342,ko:K13503,ko:K13950	ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00400,map00790,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HPEMBLHF_01467	1.71e-144	-	4.1.3.38	-	E	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	branched-chain-amino-acid transaminase activity
HPEMBLHF_01468	1.11e-312	-	5.1.3.8	-	G	ko:K01787	ko00520,map00520	ko00000,ko00001,ko01000	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
HPEMBLHF_01469	4.61e-222	-	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
HPEMBLHF_01470	0.0	-	-	-	-	-	-	-	-
HPEMBLHF_01471	6.68e-190	-	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HPEMBLHF_01472	0.0	-	-	-	D	-	-	-	Tetratricopeptide repeat
HPEMBLHF_01473	3.16e-297	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HPEMBLHF_01474	0.0	-	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminus
HPEMBLHF_01475	2.52e-102	MA20_05485	-	-	S	-	-	-	Putative bacterial sensory transduction regulator
HPEMBLHF_01476	2.64e-247	-	-	-	M	-	-	-	HlyD family secretion protein
HPEMBLHF_01477	0.0	-	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	Helix-hairpin-helix class 2 (Pol1 family) motifs
HPEMBLHF_01478	7.42e-125	-	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Phosphoribosyl transferase domain
HPEMBLHF_01480	1.93e-143	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HPEMBLHF_01481	4.18e-243	-	-	-	S	-	-	-	Imelysin
HPEMBLHF_01482	0.0	-	-	-	C	-	-	-	Di-haem oxidoreductase, putative peroxidase
HPEMBLHF_01483	8.72e-258	-	-	-	J	-	-	-	Endoribonuclease L-PSP
HPEMBLHF_01484	1.53e-219	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion homeostasis
HPEMBLHF_01485	1.01e-227	fatC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion homeostasis
HPEMBLHF_01486	2.49e-179	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HPEMBLHF_01487	1.99e-208	fatB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion transport
HPEMBLHF_01488	7.6e-176	ccs1	-	-	O	ko:K07399	-	ko00000	cytochrome c biogenesis protein
HPEMBLHF_01489	0.0	-	-	-	O	-	-	-	Cytochrome C assembly protein
HPEMBLHF_01490	8.08e-234	-	-	-	S	-	-	-	Acyltransferase family
HPEMBLHF_01491	0.0	-	-	-	G	-	-	-	beta-N-acetylhexosaminidase activity
HPEMBLHF_01492	3.22e-103	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
HPEMBLHF_01493	1.33e-51	-	-	-	C	-	-	-	4Fe-4S single cluster domain of Ferredoxin I
HPEMBLHF_01494	0.0	-	-	GT2	M	ko:K03820	-	ko00000,ko01000	Carbon-nitrogen hydrolase
HPEMBLHF_01495	3.15e-176	-	-	-	S	-	-	-	Phosphodiester glycosidase
HPEMBLHF_01496	1.05e-226	-	2.7.7.13	-	JM	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HPEMBLHF_01497	0.0	fabZ	3.5.1.108, 4.2.1.59	-	IM	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis
HPEMBLHF_01499	5.39e-224	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
HPEMBLHF_01500	1.66e-75	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPEMBLHF_01501	3.2e-270	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
HPEMBLHF_01505	1.46e-204	-	-	-	L	ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
HPEMBLHF_01506	1.26e-267	-	2.1.1.72	-	H	ko:K07318	-	ko00000,ko01000,ko02048	PFAM D12 class N6 adenine-specific DNA methyltransferase
HPEMBLHF_01508	2.08e-240	BT0173	-	-	S	-	-	-	Psort location Cytoplasmic, score
HPEMBLHF_01509	1.06e-169	BT0174	-	-	C	ko:K04488	-	ko00000	iron-sulfur transferase activity
HPEMBLHF_01510	5.74e-200	lpxG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
HPEMBLHF_01512	8.29e-100	cysJ	1.8.1.2	-	C	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	hydroxylamine reductase activity
HPEMBLHF_01514	1.23e-252	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HPEMBLHF_01515	1.33e-52	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HPEMBLHF_01516	5.52e-302	-	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
HPEMBLHF_01518	5.22e-312	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HPEMBLHF_01519	4.29e-84	-	-	-	S	ko:K06940	-	ko00000	Putative zinc- or iron-chelating domain
HPEMBLHF_01522	5.03e-192	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Bacitracin resistance protein BacA
HPEMBLHF_01523	2.6e-238	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HPEMBLHF_01524	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HPEMBLHF_01525	0.0	kefA	-	-	M	ko:K05802,ko:K22051	-	ko00000,ko02000	cellular water homeostasis
HPEMBLHF_01526	1.71e-95	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	QueF-like protein
HPEMBLHF_01527	3.42e-158	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Queuosine biosynthesis protein QueC
HPEMBLHF_01528	9.88e-145	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HPEMBLHF_01529	0.0	-	-	-	J	-	-	-	Beta-Casp domain
HPEMBLHF_01530	1.23e-62	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
HPEMBLHF_01531	7.12e-159	-	-	-	S	-	-	-	Protein of unknown function (DUF4230)
HPEMBLHF_01532	4.07e-304	-	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate/isopropylmalate dehydrogenase
HPEMBLHF_01533	1.08e-268	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
HPEMBLHF_01534	1.73e-36	-	-	-	E	ko:K07032	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HPEMBLHF_01536	0.0	-	-	-	C	-	-	-	Cytochrome c
HPEMBLHF_01537	5.51e-283	-	-	-	P	-	-	-	ABC-type Zn2 transport system, periplasmic component surface adhesin
HPEMBLHF_01538	7.28e-138	-	-	-	C	-	-	-	Cytochrome c
HPEMBLHF_01540	0.0	-	-	-	C	ko:K00185	-	ko00000	Polysulphide reductase, NrfD
HPEMBLHF_01541	3.4e-231	-	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	chorismate binding enzyme
HPEMBLHF_01542	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 31
HPEMBLHF_01543	3.66e-315	-	-	-	G	-	-	-	Glycosyl transferase 4-like domain
HPEMBLHF_01544	4.97e-292	-	3.2.1.1	GH57	G	ko:K07405	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 57
HPEMBLHF_01545	8.02e-130	-	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HPEMBLHF_01546	1.05e-92	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transport protein ExbD/TolR
HPEMBLHF_01547	2.2e-134	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
HPEMBLHF_01548	1.3e-283	-	5.4.99.22	-	M	ko:K06178	-	ko00000,ko01000,ko03009	translation initiation factor activity
HPEMBLHF_01549	3.77e-118	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
HPEMBLHF_01550	3.48e-315	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
HPEMBLHF_01551	6.75e-144	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
HPEMBLHF_01552	0.0	fhs	6.3.4.3	-	H	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate--tetrahydrofolate ligase
HPEMBLHF_01553	5.31e-218	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Ketopantoate reductase PanE/ApbA C terminal
HPEMBLHF_01554	6.44e-206	-	-	-	S	-	-	-	Tetratricopeptide repeat
HPEMBLHF_01555	1.4e-185	-	-	-	T	-	-	-	Calcineurin-like phosphoesterase superfamily domain
HPEMBLHF_01556	0.0	-	-	-	EP	ko:K13894	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPEMBLHF_01557	0.0	-	-	-	P	ko:K13895	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPEMBLHF_01558	0.0	-	-	-	E	ko:K13893	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HPEMBLHF_01559	7.73e-231	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HPEMBLHF_01560	3.08e-242	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HPEMBLHF_01561	2.2e-274	-	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HPEMBLHF_01563	2.57e-120	-	-	-	L	-	-	-	endonuclease activity
HPEMBLHF_01564	1.06e-172	-	-	-	EG	-	-	-	EamA-like transporter family
HPEMBLHF_01565	0.0	-	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
HPEMBLHF_01566	3.23e-220	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HPEMBLHF_01568	1.07e-138	-	-	-	K	-	-	-	ECF sigma factor
HPEMBLHF_01569	3.48e-217	ytpP	2.7.1.180, 5.3.4.1	-	CO	ko:K01829,ko:K03671,ko:K03734,ko:K06196	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko02000,ko03110	cell redox homeostasis
HPEMBLHF_01570	0.0	-	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	ThiC-associated domain
HPEMBLHF_01571	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HPEMBLHF_01572	7.29e-60	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	negative regulation of transcription, DNA-templated
HPEMBLHF_01573	8.73e-135	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
HPEMBLHF_01574	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	N-terminal domain of BNR-repeat neuraminidase
HPEMBLHF_01575	9.18e-121	-	-	-	-	-	-	-	-
HPEMBLHF_01576	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
HPEMBLHF_01577	0.0	fucI	5.3.1.25, 5.3.1.3	-	G	ko:K01818	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Converts the aldose L-fucose into the corresponding ketose L-fuculose
HPEMBLHF_01578	0.0	-	2.7.1.51	-	G	ko:K00879	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
HPEMBLHF_01579	1.03e-201	-	-	-	G	-	-	-	Class II Aldolase and Adducin N-terminal domain
HPEMBLHF_01581	0.0	-	-	-	M	-	-	-	AsmA-like C-terminal region
HPEMBLHF_01582	5.58e-141	-	-	-	S	ko:K06911	-	ko00000	Pirin
HPEMBLHF_01584	2.05e-173	-	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	FtsJ-like methyltransferase
HPEMBLHF_01588	2.45e-216	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HPEMBLHF_01589	1.25e-282	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HPEMBLHF_01590	4.7e-57	-	-	-	S	ko:K06960	-	ko00000	KH domain
HPEMBLHF_01591	0.0	-	-	-	-	-	-	-	-
HPEMBLHF_01592	0.0	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	RNA cap guanine-N2 methyltransferase
HPEMBLHF_01593	7.51e-217	-	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HPEMBLHF_01594	4.17e-235	-	4.2.1.113	-	M	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Mandelate Racemase Muconate Lactonizing
HPEMBLHF_01596	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
HPEMBLHF_01598	0.0	-	-	-	V	-	-	-	Polysaccharide biosynthesis C-terminal domain
HPEMBLHF_01599	0.0	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HPEMBLHF_01600	1.65e-102	-	-	-	G	-	-	-	single-species biofilm formation
HPEMBLHF_01601	7.97e-113	-	-	-	K	ko:K13640	-	ko00000,ko03000	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HPEMBLHF_01602	4.8e-128	-	-	-	S	-	-	-	Flavodoxin-like fold
HPEMBLHF_01603	1.11e-188	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin domain
HPEMBLHF_01604	4.01e-100	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HPEMBLHF_01605	9.98e-129	-	-	-	C	-	-	-	FMN binding
HPEMBLHF_01606	3.6e-265	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
HPEMBLHF_01607	1.48e-270	-	-	-	C	-	-	-	Aldo/keto reductase family
HPEMBLHF_01608	1.41e-266	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
HPEMBLHF_01609	7.86e-207	-	-	-	S	-	-	-	Aldo/keto reductase family
HPEMBLHF_01610	7.1e-216	-	1.2.7.3	-	-	ko:K00176,ko:K07138	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	br01601,ko00000,ko00001,ko00002,ko01000	-
HPEMBLHF_01611	1.23e-295	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
HPEMBLHF_01612	1.08e-139	-	-	-	M	-	-	-	polygalacturonase activity
HPEMBLHF_01614	2.71e-191	-	-	-	KT	-	-	-	Peptidase S24-like
HPEMBLHF_01615	4.13e-218	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HPEMBLHF_01616	1.14e-45	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HPEMBLHF_01619	2.39e-178	-	-	-	O	-	-	-	Trypsin
HPEMBLHF_01620	3.31e-239	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HPEMBLHF_01621	1.78e-202	-	-	-	-	-	-	-	-
HPEMBLHF_01622	0.0	-	-	-	S	-	-	-	Sulfatase-modifying factor enzyme 1
HPEMBLHF_01623	2.51e-280	-	-	-	S	-	-	-	Tetratricopeptide repeat
HPEMBLHF_01625	2.63e-10	-	-	-	-	-	-	-	-
HPEMBLHF_01627	5.79e-62	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPEMBLHF_01628	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HPEMBLHF_01629	2.48e-228	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HPEMBLHF_01630	8.84e-211	-	-	-	S	-	-	-	Protein of unknown function DUF58
HPEMBLHF_01631	4.66e-133	-	-	-	-	-	-	-	-
HPEMBLHF_01632	1.33e-228	-	-	-	S	-	-	-	Protein of unknown function (DUF1194)
HPEMBLHF_01635	8.51e-42	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
HPEMBLHF_01636	0.0	-	-	-	S	-	-	-	Oxygen tolerance
HPEMBLHF_01637	1.16e-205	yeaE	-	-	S	-	-	-	aldo-keto reductase (NADP) activity
HPEMBLHF_01638	0.0	-	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Anticodon binding domain
HPEMBLHF_01639	4.64e-150	-	-	-	S	-	-	-	DUF218 domain
HPEMBLHF_01640	1.3e-198	-	-	-	S	-	-	-	CAAX protease self-immunity
HPEMBLHF_01641	1.3e-285	-	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Cys/Met metabolism PLP-dependent enzyme
HPEMBLHF_01642	8.26e-106	-	-	-	K	-	-	-	Lrp/AsnC ligand binding domain
HPEMBLHF_01643	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
HPEMBLHF_01644	2.44e-167	-	-	-	V	ko:K19147	-	ko00000,ko02048	McrBC 5-methylcytosine restriction system component
HPEMBLHF_01645	1.95e-247	-	-	-	V	ko:K07452	-	ko00000,ko01000,ko02048	AAA domain (dynein-related subfamily)
HPEMBLHF_01646	7.28e-79	-	-	-	P	ko:K06195	-	ko00000	ApaG domain
HPEMBLHF_01647	1.76e-201	-	-	-	-	-	-	-	-
HPEMBLHF_01648	0.0	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HPEMBLHF_01649	1.74e-191	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HPEMBLHF_01650	1.88e-135	-	-	-	K	ko:K07735	-	ko00000,ko03000	Uncharacterized ACR, COG1678
HPEMBLHF_01651	5.88e-163	-	-	-	S	ko:K06997	-	ko00000	Alanine racemase, N-terminal domain
HPEMBLHF_01652	0.0	-	-	-	S	-	-	-	50S ribosome-binding GTPase
HPEMBLHF_01653	2.75e-137	-	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
HPEMBLHF_01654	1.46e-207	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPEMBLHF_01655	0.0	-	-	-	E	-	-	-	Peptidase dimerisation domain
HPEMBLHF_01656	1.48e-221	hprK	-	-	T	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)
HPEMBLHF_01657	8.72e-53	-	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
HPEMBLHF_01658	0.0	-	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HPEMBLHF_01659	0.0	-	-	-	P	-	-	-	Sulfatase
HPEMBLHF_01660	7.81e-222	-	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HPEMBLHF_01661	2.06e-93	-	-	-	S	ko:K02426	-	ko00000	Fe-S metabolism associated domain
HPEMBLHF_01663	0.0	-	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha amylase, C-terminal all-beta domain
HPEMBLHF_01664	4.85e-261	-	-	-	M	ko:K07271	-	ko00000,ko01000	LICD family
HPEMBLHF_01665	0.0	cobD	2.6.1.9, 2.7.7.74, 4.1.1.81	-	M	ko:K00817,ko:K04720,ko:K07281	ko00340,ko00350,ko00360,ko00400,ko00401,ko00562,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00562,map00860,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	nucleotidyl transferase
HPEMBLHF_01666	3.57e-264	odh	1.5.1.28	-	I	ko:K04940	-	ko00000,ko01000	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HPEMBLHF_01667	0.0	-	2.7.7.15	-	H	ko:K00968	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
HPEMBLHF_01668	8.51e-225	-	-	-	M	ko:K07271	-	ko00000,ko01000	LICD family
HPEMBLHF_01669	2.72e-129	-	-	-	S	-	-	-	protein trimerization
HPEMBLHF_01671	1.05e-173	-	2.1.1.144, 2.1.1.197	-	FG	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	trans-aconitate 2-methyltransferase activity
HPEMBLHF_01672	0.0	-	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP--glucose-1-phosphate uridylyltransferase
HPEMBLHF_01673	4.06e-115	-	-	-	-	-	-	-	-
HPEMBLHF_01674	1.12e-63	-	-	-	J	-	-	-	RF-1 domain
HPEMBLHF_01675	1.47e-121	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HPEMBLHF_01676	1.79e-267	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
HPEMBLHF_01677	1.39e-276	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
HPEMBLHF_01679	1.15e-146	-	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HPEMBLHF_01680	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HPEMBLHF_01682	4.89e-237	-	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Delta-aminolevulinic acid dehydratase
HPEMBLHF_01684	6.82e-159	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HPEMBLHF_01685	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HPEMBLHF_01686	1.62e-229	-	4.1.1.35	-	M	ko:K08678	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko00002,ko01000	3-beta hydroxysteroid dehydrogenase/isomerase family
HPEMBLHF_01687	1.34e-177	-	-	-	I	-	-	-	Acyl-ACP thioesterase
HPEMBLHF_01688	2.77e-28	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HPEMBLHF_01689	9.87e-06	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HPEMBLHF_01692	1.84e-56	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HPEMBLHF_01696	6.52e-139	nuoB	1.6.5.3	-	C	ko:K00331	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPEMBLHF_01697	2.1e-140	nuoC	1.6.5.3	-	C	ko:K00332	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPEMBLHF_01698	1.14e-166	-	-	-	-	-	-	-	-
HPEMBLHF_01699	1.27e-70	-	-	-	K	-	-	-	ribonuclease III activity
HPEMBLHF_01700	4.14e-279	-	6.2.1.26	-	IQ	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	AMP-binding enzyme
HPEMBLHF_01702	0.0	-	-	-	S	ko:K07126,ko:K13582	ko04112,map04112	ko00000,ko00001	beta-lactamase activity
HPEMBLHF_01703	5.14e-05	-	-	-	-	-	-	-	-
HPEMBLHF_01704	0.0	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HPEMBLHF_01705	0.0	-	3.4.24.70	-	E	ko:K01414	-	ko00000,ko01000,ko01002	Peptidase family M3
HPEMBLHF_01708	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl tRNA synthetase N terminal dom
HPEMBLHF_01710	6.52e-216	-	-	-	K	-	-	-	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
HPEMBLHF_01711	1.73e-123	paiA	-	-	K	-	-	-	acetyltransferase
HPEMBLHF_01712	1.59e-223	-	-	-	CO	-	-	-	Redoxin
HPEMBLHF_01713	3.74e-82	-	-	-	K	ko:K07343	-	ko00000	positive regulation of type IV pilus biogenesis
HPEMBLHF_01714	2.38e-173	-	6.3.5.11, 6.3.5.9	-	V	ko:K02224,ko:K18554	ko00860,ko01100,ko01120,map00860,map01100,map01120	br01600,ko00000,ko00001,ko01000,ko01504	Chloramphenicol phosphotransferase-like protein
HPEMBLHF_01716	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HPEMBLHF_01717	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HPEMBLHF_01718	1.01e-251	-	2.3.1.1	-	E	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetyltransferase (GNAT) family
HPEMBLHF_01721	3.19e-115	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	nUDIX hydrolase
HPEMBLHF_01722	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HPEMBLHF_01723	1.81e-222	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HPEMBLHF_01724	1.01e-182	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HPEMBLHF_01725	0.0	-	-	-	N	-	-	-	ABC-type uncharacterized transport system
HPEMBLHF_01726	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4340)
HPEMBLHF_01727	3.17e-190	-	-	-	S	-	-	-	NIF3 (NGG1p interacting factor 3)
HPEMBLHF_01728	3.72e-237	-	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HPEMBLHF_01729	9.77e-278	-	4.2.1.51, 5.4.99.5	-	E	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
HPEMBLHF_01730	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HPEMBLHF_01731	0.0	-	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HPEMBLHF_01732	3.6e-145	-	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	CDP-alcohol phosphatidyltransferase
HPEMBLHF_01734	2.25e-284	-	3.6.4.13	-	L	ko:K11927	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	helicase superfamily c-terminal domain
HPEMBLHF_01736	0.0	-	-	-	S	-	-	-	inositol 2-dehydrogenase activity
HPEMBLHF_01737	4.21e-290	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HPEMBLHF_01738	8.62e-225	-	3.4.11.10, 3.4.11.6	-	DZ	ko:K19701	-	ko00000,ko01000,ko01002	aminopeptidase activity
HPEMBLHF_01739	2.23e-272	ycaD	-	-	EGP	ko:K08219	-	ko00000,ko02000	Major facilitator Superfamily
HPEMBLHF_01740	2.68e-316	-	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, Activator interacting domain (AID)
HPEMBLHF_01741	2.71e-175	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HPEMBLHF_01742	1.05e-161	-	-	-	S	-	-	-	Phenazine biosynthesis-like protein
HPEMBLHF_01744	1.03e-138	mntP	-	-	P	-	-	-	manganese ion transmembrane transporter activity
HPEMBLHF_01745	0.0	-	-	-	-	-	-	-	-
HPEMBLHF_01746	3.39e-295	-	-	-	-	-	-	-	-
HPEMBLHF_01747	0.0	-	-	-	L	ko:K07478	-	ko00000	MgsA AAA+ ATPase C terminal
HPEMBLHF_01749	2.37e-221	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NmrA-like family
HPEMBLHF_01750	8.25e-273	-	-	-	S	-	-	-	Phosphotransferase enzyme family
HPEMBLHF_01751	6.79e-217	-	-	-	JM	-	-	-	Nucleotidyl transferase
HPEMBLHF_01753	3.39e-157	-	-	-	S	-	-	-	Peptidase family M50
HPEMBLHF_01754	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Prolyl-tRNA synthetase, C-terminal
HPEMBLHF_01758	1.39e-78	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HPEMBLHF_01760	1.37e-80	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HPEMBLHF_01762	0.0	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HPEMBLHF_01763	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
HPEMBLHF_01764	8.6e-222	-	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Glutaminase
HPEMBLHF_01765	5.74e-94	-	-	-	K	-	-	-	-acetyltransferase
HPEMBLHF_01766	2.89e-308	-	-	-	E	ko:K03310	-	ko00000	Sodium:alanine symporter family
HPEMBLHF_01768	3.95e-252	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HPEMBLHF_01769	1.12e-211	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HPEMBLHF_01770	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HPEMBLHF_01771	1.25e-199	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HPEMBLHF_01775	4.33e-161	menG	2.1.1.163, 2.1.1.201	-	Q	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	ubiE/COQ5 methyltransferase family
HPEMBLHF_01776	0.0	-	-	-	V	-	-	-	MatE
HPEMBLHF_01778	6.26e-30	-	-	-	S	-	-	-	PFAM Archaeal ATPase
HPEMBLHF_01779	8.52e-15	-	-	-	S	-	-	-	PFAM FRG domain
HPEMBLHF_01784	5.46e-22	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	HMGL-like
HPEMBLHF_01785	0.0	-	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
HPEMBLHF_01786	0.0	hyl	2.3.1.48, 3.2.1.169, 3.2.1.35	GH84	G	ko:K01197,ko:K15719	ko00531,ko01100,ko04931,map00531,map01100,map04931	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylhexosaminidase activity
HPEMBLHF_01788	4.77e-219	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
HPEMBLHF_01789	2.88e-91	-	-	-	-	-	-	-	-
HPEMBLHF_01790	9.82e-189	-	-	-	P	ko:K09820	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HPEMBLHF_01791	6.95e-183	-	-	-	P	ko:K09819	-	ko00000,ko00002,ko02000	FecCD transport family
HPEMBLHF_01792	5.46e-126	-	-	-	S	ko:K19411	-	ko00000	UvrB/uvrC motif
HPEMBLHF_01793	2.26e-243	-	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	ATP:guanido phosphotransferase, C-terminal catalytic domain
HPEMBLHF_01794	0.0	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
HPEMBLHF_01795	0.0	-	3.2.1.50	-	G	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha-L-fucosidase
HPEMBLHF_01796	1.93e-63	-	-	-	P	ko:K03972	-	ko00000	Rhodanese Homology Domain
HPEMBLHF_01797	2.1e-201	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
HPEMBLHF_01798	0.0	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	HMGL-like
HPEMBLHF_01799	1.28e-223	-	-	-	CO	-	-	-	amine dehydrogenase activity
HPEMBLHF_01800	2.55e-94	-	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
HPEMBLHF_01801	2.05e-163	-	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
HPEMBLHF_01802	1.78e-204	-	-	-	GM	-	-	-	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HPEMBLHF_01803	2.41e-232	-	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (W and Y)
HPEMBLHF_01804	1.56e-103	-	-	-	T	-	-	-	Universal stress protein family
HPEMBLHF_01805	1.45e-190	-	-	-	S	ko:K09769	-	ko00000	YmdB-like protein
HPEMBLHF_01806	8.33e-184	-	-	-	H	ko:K22132	-	ko00000,ko03016	ThiF family
HPEMBLHF_01807	9.9e-121	-	-	-	-	-	-	-	-
HPEMBLHF_01809	1.65e-56	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPEMBLHF_01811	7.68e-52	-	-	-	S	-	-	-	Protease prsW family
HPEMBLHF_01812	6.57e-05	-	-	-	-	-	-	-	-
HPEMBLHF_01813	0.000188	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
HPEMBLHF_01820	2.19e-28	-	-	-	KLT	-	-	-	COG0515 Serine threonine protein kinase
HPEMBLHF_01821	1.42e-69	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
HPEMBLHF_01822	3.53e-81	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HPEMBLHF_01823	0.0	recD2_4	-	-	L	-	-	-	DNA replication, synthesis of RNA primer
HPEMBLHF_01826	2.5e-07	-	-	-	V	ko:K07448	-	ko00000,ko02048	Restriction endonuclease
HPEMBLHF_01831	2.21e-96	-	-	-	S	-	-	-	Domain of unknown function (DUF932)
HPEMBLHF_01832	1.28e-128	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	HipA-like C-terminal domain
HPEMBLHF_01833	4.29e-38	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	HipA N-terminal domain
HPEMBLHF_01834	1.49e-06	-	-	-	K	-	-	-	Helix-turn-helix domain
HPEMBLHF_01835	1.26e-38	-	-	-	-	-	-	-	-
HPEMBLHF_01843	2.61e-05	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
HPEMBLHF_01844	2.25e-229	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HPEMBLHF_01845	3.09e-122	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HPEMBLHF_01846	1.08e-288	kbl	2.3.1.29	-	E	ko:K00639	ko00260,map00260	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
HPEMBLHF_01847	0.0	-	-	-	KLT	-	-	-	Sulfatase-modifying factor enzyme 1
HPEMBLHF_01848	3.54e-181	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	AAA domain
HPEMBLHF_01849	0.0	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
HPEMBLHF_01856	2.09e-54	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
HPEMBLHF_01857	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HPEMBLHF_01858	0.0	-	-	-	M	ko:K02847,ko:K13009,ko:K16705	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	-O-antigen
HPEMBLHF_01859	8.67e-85	-	-	-	S	-	-	-	Protein of unknown function, DUF488
HPEMBLHF_01861	4.11e-226	-	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Porphobilinogen deaminase, dipyromethane cofactor binding domain
HPEMBLHF_01862	9.88e-241	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Glutamyl-tRNAGlu reductase, N-terminal domain
HPEMBLHF_01863	1.02e-178	-	-	-	S	-	-	-	Cytochrome C assembly protein
HPEMBLHF_01864	3.84e-189	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Type I GTP cyclohydrolase folE2
HPEMBLHF_01865	4.52e-49	-	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S18
HPEMBLHF_01866	5.67e-33	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
HPEMBLHF_01867	1.46e-118	-	-	-	T	-	-	-	Prokaryotic dksA/traR C4-type zinc finger
HPEMBLHF_01868	5.9e-232	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HPEMBLHF_01869	2.01e-245	sun	2.1.1.176, 2.1.1.178	-	J	ko:K03500,ko:K11392	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HPEMBLHF_01870	4.56e-125	-	-	-	S	ko:K07095	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HPEMBLHF_01871	5.75e-98	nudI	3.6.1.55	-	F	ko:K03574,ko:K12944	-	ko00000,ko01000,ko03400	GDP-mannose mannosyl hydrolase activity
HPEMBLHF_01872	4.14e-297	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPEMBLHF_01873	6.61e-73	-	-	-	S	-	-	-	COG3943, virulence protein
HPEMBLHF_01874	1.19e-279	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPEMBLHF_01875	2.09e-217	-	-	-	L	-	-	-	DNA primase
HPEMBLHF_01876	1.19e-296	-	-	-	D	-	-	-	plasmid recombination enzyme
HPEMBLHF_01878	1.67e-157	-	-	-	S	-	-	-	Protein of unknown function DUF262
HPEMBLHF_01879	1.57e-189	-	2.1.1.184	-	J	ko:K00561	-	br01600,ko00000,ko01000,ko01504,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family
HPEMBLHF_01880	4.05e-204	-	-	-	C	-	-	-	Nitroreductase family
HPEMBLHF_01881	2.12e-64	-	-	-	S	-	-	-	Protein of unknown function DUF262
HPEMBLHF_01882	2.88e-283	-	-	-	M	ko:K02005	-	ko00000	HlyD family secretion protein
HPEMBLHF_01883	6.09e-162	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPEMBLHF_01884	3.42e-313	-	-	-	V	-	-	-	MacB-like periplasmic core domain
HPEMBLHF_01885	9.1e-317	-	-	-	MU	-	-	-	Outer membrane efflux protein
HPEMBLHF_01886	1.57e-284	-	-	-	V	-	-	-	Beta-lactamase
HPEMBLHF_01887	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HPEMBLHF_01888	1.72e-282	mtrC	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPEMBLHF_01889	2.91e-94	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HPEMBLHF_01894	4.97e-78	-	-	-	L	-	-	-	Transposase and inactivated derivatives
HPEMBLHF_01896	2.15e-166	-	-	-	S	-	-	-	Uncharacterised protein family UPF0066
HPEMBLHF_01897	3.91e-306	-	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydro-orotase-like
HPEMBLHF_01898	1.55e-222	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
HPEMBLHF_01899	1.15e-122	-	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Phosphoribosyl transferase domain
HPEMBLHF_01900	3.73e-90	-	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	AIR carboxylase
HPEMBLHF_01902	0.0	-	-	-	H	ko:K07137	-	ko00000	5-formyltetrahydrofolate cyclo-ligase activity
HPEMBLHF_01903	6.45e-268	-	3.5.3.12	-	E	ko:K10536	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Porphyromonas-type peptidyl-arginine deiminase
HPEMBLHF_01904	2.11e-89	-	-	-	-	-	-	-	-
HPEMBLHF_01905	0.0	rseP	3.4.21.116	-	M	ko:K06399,ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	metalloendopeptidase activity
HPEMBLHF_01906	4.16e-282	-	-	-	S	-	-	-	AI-2E family transporter
HPEMBLHF_01907	0.0	-	-	-	P	-	-	-	Domain of unknown function
HPEMBLHF_01909	2.25e-111	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HPEMBLHF_01910	1.12e-312	-	-	-	G	-	-	-	cellulose 1,4-beta-cellobiosidase activity
HPEMBLHF_01911	1.42e-184	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HPEMBLHF_01913	5.26e-74	-	-	-	-	-	-	-	-
HPEMBLHF_01914	0.0	-	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	DNA Topoisomerase IV
HPEMBLHF_01916	7.17e-130	-	-	-	S	-	-	-	Glycosyl hydrolase 108
HPEMBLHF_01919	4.83e-198	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	ParB-like nuclease domain
HPEMBLHF_01920	3.02e-227	-	-	-	S	-	-	-	Peptidase family M28
HPEMBLHF_01921	0.0	-	-	-	M	-	-	-	Aerotolerance regulator N-terminal
HPEMBLHF_01922	0.0	-	-	-	S	-	-	-	Large extracellular alpha-helical protein
HPEMBLHF_01925	1.11e-235	-	-	-	S	ko:K14347	-	ko00000,ko02000,ko04147	SBF-like CPA transporter family (DUF4137)
HPEMBLHF_01926	6.2e-271	-	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	tRNA synthetases class I (W and Y)
HPEMBLHF_01927	8.28e-84	-	-	-	S	ko:K09922	-	ko00000	Putative member of DMT superfamily (DUF486)
HPEMBLHF_01928	3.1e-211	-	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
HPEMBLHF_01929	5.13e-214	-	-	-	EP	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPEMBLHF_01930	0.0	-	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HPEMBLHF_01931	1.37e-211	-	-	-	O	-	-	-	Thioredoxin-like domain
HPEMBLHF_01932	1.53e-309	-	1.5.1.7	-	E	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Saccharopine dehydrogenase C-terminal domain
HPEMBLHF_01933	6.27e-229	-	-	-	S	ko:K01128	-	ko00000,ko01000	acid phosphatase activity
HPEMBLHF_01938	1.75e-301	-	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Tubulin/FtsZ family, GTPase domain
HPEMBLHF_01939	6.55e-292	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HPEMBLHF_01940	3.9e-144	-	-	-	M	-	-	-	NLP P60 protein
HPEMBLHF_01941	0.0	-	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
HPEMBLHF_01942	0.0	-	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter transmembrane region
HPEMBLHF_01943	0.0	-	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter transmembrane region
HPEMBLHF_01944	7.65e-308	-	-	-	H	-	-	-	NAD synthase
HPEMBLHF_01945	3.2e-173	-	-	-	Q	ko:K02066	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Permease MlaE
HPEMBLHF_01946	3.54e-189	-	-	-	Q	ko:K02065	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPEMBLHF_01947	4.46e-230	-	-	-	Q	ko:K02067	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	MlaD protein
HPEMBLHF_01948	2.69e-38	-	-	-	T	-	-	-	ribosome binding
HPEMBLHF_01951	5.1e-265	-	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
HPEMBLHF_01952	5.27e-260	-	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
HPEMBLHF_01953	3.92e-247	ppiD	5.2.1.8	-	O	ko:K03769,ko:K03770,ko:K03771,ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl cis-trans isomerase activity
HPEMBLHF_01955	0.0	-	-	-	-	-	-	-	-
HPEMBLHF_01956	1.14e-178	kdsB	2.7.7.38	-	M	ko:K00979	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HPEMBLHF_01957	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HPEMBLHF_01958	0.0	-	-	-	E	-	-	-	Sodium:solute symporter family
HPEMBLHF_01960	5.95e-96	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HPEMBLHF_01961	1.67e-174	-	-	-	S	-	-	-	Lysin motif
HPEMBLHF_01962	7.48e-127	-	-	-	-	-	-	-	-
HPEMBLHF_01963	8.56e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Phosphopantetheine attachment site
HPEMBLHF_01964	5.89e-173	coaX	2.7.1.33	-	K	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Type III pantothenate kinase
HPEMBLHF_01965	9.94e-266	-	-	-	M	-	-	-	Monogalactosyldiacylglycerol (MGDG) synthase
HPEMBLHF_01966	2.62e-225	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HPEMBLHF_01967	0.0	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD-like helicase C-terminal domain
HPEMBLHF_01969	0.0	-	-	-	S	ko:K03307	-	ko00000	Sodium:solute symporter family
HPEMBLHF_01970	7.29e-283	-	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Galactokinase galactose-binding signature
HPEMBLHF_01971	0.0	-	-	-	M	-	-	-	Bacterial sugar transferase
HPEMBLHF_01972	8.19e-140	-	-	-	S	-	-	-	RNA recognition motif
HPEMBLHF_01973	1.44e-184	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HPEMBLHF_01974	0.0	-	-	-	-	-	-	-	-
HPEMBLHF_01976	0.0	-	-	-	V	-	-	-	ABC-2 type transporter
HPEMBLHF_01977	0.0	-	-	-	C	-	-	-	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein
HPEMBLHF_01978	5.47e-202	-	-	-	S	-	-	-	Domain of unknown function (DUF362)
HPEMBLHF_01979	1.37e-131	-	-	-	J	-	-	-	Putative rRNA methylase
HPEMBLHF_01980	7.02e-144	-	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HPEMBLHF_01981	3.73e-195	-	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
HPEMBLHF_01982	2.27e-288	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	NusA-like KH domain
HPEMBLHF_01983	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HPEMBLHF_01984	2e-82	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HPEMBLHF_01985	0.0	-	-	-	P	-	-	-	PA14 domain
HPEMBLHF_01986	1.77e-15	-	-	-	-	-	-	-	-
HPEMBLHF_01987	0.0	-	-	-	T	-	-	-	5TM C-terminal transporter carbon starvation CstA
HPEMBLHF_01988	0.0	-	-	-	EGIP	-	-	-	Phosphate acyltransferases
HPEMBLHF_01989	1.11e-132	-	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HPEMBLHF_01990	1.25e-283	-	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HPEMBLHF_01991	1.64e-222	-	-	-	C	-	-	-	e3 binding domain
HPEMBLHF_01992	1.6e-127	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HPEMBLHF_01993	8.81e-265	-	-	-	S	-	-	-	PFAM glycosyl transferase family 2
HPEMBLHF_01994	2.56e-271	-	-	-	-	-	-	-	-
HPEMBLHF_01995	5.17e-249	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HPEMBLHF_01996	2.36e-151	-	-	-	S	-	-	-	Glycosyl transferase family 11
HPEMBLHF_01997	9.43e-272	-	-	GT2	S	ko:K19427	-	ko00000,ko01000	PFAM glycosyl transferase family 2
HPEMBLHF_01999	5.41e-277	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
HPEMBLHF_02000	0.0	-	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Polyphosphate kinase middle domain
HPEMBLHF_02001	0.0	-	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
HPEMBLHF_02002	3.55e-258	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
HPEMBLHF_02003	6.15e-191	map	3.4.11.18	-	J	ko:K01265	-	ko00000,ko01000,ko01002	Metallopeptidase family M24
HPEMBLHF_02004	1.76e-152	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HPEMBLHF_02005	0.0	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HPEMBLHF_02007	6.42e-101	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
HPEMBLHF_02008	3.38e-102	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HPEMBLHF_02009	6.82e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HPEMBLHF_02010	9.16e-105	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HPEMBLHF_02011	4.08e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HPEMBLHF_02012	5.36e-138	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HPEMBLHF_02013	1.53e-47	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal proteins 50S L24/mitochondrial 39S L24
HPEMBLHF_02014	2.33e-205	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HPEMBLHF_02015	2.07e-123	-	-	-	M	ko:K03642	-	ko00000	Lytic transglycolase
HPEMBLHF_02016	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HPEMBLHF_02017	0.0	-	2.7.11.1	-	L	ko:K08282	-	ko00000,ko01000	SNF2 Helicase protein
HPEMBLHF_02018	0.0	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HPEMBLHF_02020	4.81e-274	-	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
HPEMBLHF_02021	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Collagenase
HPEMBLHF_02022	2.4e-23	-	-	-	M	ko:K13730	ko05100,map05100	ko00000,ko00001	leucine-rich repeat-containing protein typical subtype
HPEMBLHF_02026	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HPEMBLHF_02027	7.34e-72	-	-	-	L	-	-	-	Cupin 2, conserved barrel domain protein
HPEMBLHF_02028	1.95e-127	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
HPEMBLHF_02030	7.13e-295	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HPEMBLHF_02031	1.12e-213	-	-	-	K	-	-	-	LysR substrate binding domain
HPEMBLHF_02032	2.76e-270	-	-	-	S	-	-	-	tRNA-splicing ligase RtcB
HPEMBLHF_02033	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
HPEMBLHF_02035	1.45e-283	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HPEMBLHF_02037	2.57e-133	-	-	-	D	-	-	-	ErfK ybiS ycfS ynhG family protein
HPEMBLHF_02038	0.0	-	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase C-terminal domain
HPEMBLHF_02039	8.8e-169	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
HPEMBLHF_02043	0.0	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Bacterial DNA topoisomeraes I ATP-binding domain
HPEMBLHF_02044	1.61e-89	-	-	-	-	-	-	-	-
HPEMBLHF_02045	0.0	-	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase HemD
HPEMBLHF_02046	2.24e-101	-	-	-	S	-	-	-	peptidase
HPEMBLHF_02047	5.18e-172	-	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
HPEMBLHF_02048	4.07e-97	-	-	-	S	-	-	-	peptidase
HPEMBLHF_02049	0.0	-	-	-	S	-	-	-	pathogenesis
HPEMBLHF_02050	0.0	-	-	-	V	ko:K18095	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01504,ko02000	AcrB/AcrD/AcrF family
HPEMBLHF_02051	7.88e-240	-	-	-	M	ko:K18094	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01504,ko02000	Biotin-lipoyl like
HPEMBLHF_02052	1.7e-195	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HPEMBLHF_02053	1.13e-221	-	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HPEMBLHF_02054	9.47e-236	-	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
HPEMBLHF_02055	3.3e-298	-	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
HPEMBLHF_02056	1.11e-204	-	-	-	S	ko:K09949	-	ko00000	Protein of unknown function (DUF1009)
HPEMBLHF_02059	4.67e-91	-	-	-	-	-	-	-	-
HPEMBLHF_02060	2.78e-171	yyaQ	-	-	V	-	-	-	Protein conserved in bacteria
HPEMBLHF_02061	2.06e-191	-	-	-	M	-	-	-	Glycosyl transferase WecB/TagA/CpsF family
HPEMBLHF_02062	3.71e-190	-	3.1.4.55	-	S	ko:K06167	ko00440,map00440	ko00000,ko00001,ko01000	Metallo-beta-lactamase superfamily
HPEMBLHF_02063	0.0	-	-	-	L	ko:K03631	-	ko00000,ko03400	RecF/RecN/SMC N terminal domain
HPEMBLHF_02064	0.0	-	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HPEMBLHF_02065	3.19e-241	-	-	-	G	-	-	-	Glycosyl hydrolases family 16
HPEMBLHF_02066	9.29e-132	-	-	-	J	ko:K02356	-	ko00000,ko03012	Elongation factor P (EF-P) OB domain
HPEMBLHF_02067	2.42e-105	-	-	-	S	-	-	-	ACT domain protein
HPEMBLHF_02068	4.8e-313	-	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HPEMBLHF_02069	3.06e-85	-	-	-	M	ko:K03282	-	ko00000,ko02000	Large-conductance mechanosensitive channel, MscL
HPEMBLHF_02070	4.43e-272	-	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
HPEMBLHF_02071	1.77e-281	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HPEMBLHF_02072	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
HPEMBLHF_02073	1.64e-263	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
HPEMBLHF_02075	4.61e-120	ngr	-	-	C	-	-	-	Rubrerythrin
HPEMBLHF_02076	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF1705)
HPEMBLHF_02077	0.0	-	-	-	M	-	-	-	Glycosyl Hydrolase Family 88
HPEMBLHF_02078	0.0	-	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
HPEMBLHF_02079	1.09e-42	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	CTP reductase activity
HPEMBLHF_02080	2.32e-183	-	1.97.1.4	-	O	ko:K04069	-	ko00000,ko01000	Radical SAM superfamily
HPEMBLHF_02081	0.0	-	-	-	P	ko:K14445	-	ko00000,ko02000	Citrate transporter
HPEMBLHF_02082	0.0	-	-	-	T	-	-	-	Histidine kinase
HPEMBLHF_02083	3.14e-109	-	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
HPEMBLHF_02084	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
HPEMBLHF_02085	3.64e-25	-	-	-	M	ko:K13730	ko05100,map05100	ko00000,ko00001	leucine-rich repeat-containing protein typical subtype
HPEMBLHF_02088	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
HPEMBLHF_02089	2.47e-53	himA	-	-	L	ko:K03530,ko:K04764,ko:K05788	-	ko00000,ko03032,ko03036,ko03400	regulation of translation
HPEMBLHF_02090	0.0	-	-	-	-	-	-	-	-
HPEMBLHF_02091	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HPEMBLHF_02092	2.66e-185	-	-	-	V	-	-	-	AAA domain
HPEMBLHF_02093	2.72e-111	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HPEMBLHF_02094	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	COG0286 Type I restriction-modification system methyltransferase subunit
HPEMBLHF_02097	1.44e-297	-	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	tRNA (Uracil-5-)-methyltransferase
HPEMBLHF_02098	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HPEMBLHF_02099	0.0	-	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
HPEMBLHF_02100	1.1e-256	-	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HPEMBLHF_02101	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HPEMBLHF_02103	4.52e-199	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HPEMBLHF_02104	5.79e-306	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HPEMBLHF_02105	0.0	-	-	-	-	-	-	-	-
HPEMBLHF_02106	1.24e-163	-	-	-	S	-	-	-	SWIM zinc finger
HPEMBLHF_02107	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Argininosuccinate lyase C-terminal
HPEMBLHF_02108	0.0	-	-	-	U	ko:K03321	-	ko00000,ko02000	Sulfate permease family
HPEMBLHF_02109	7.2e-125	-	-	-	-	-	-	-	-
HPEMBLHF_02110	1.04e-109	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HPEMBLHF_02112	0.0	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
HPEMBLHF_02114	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPEMBLHF_02116	3.69e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HPEMBLHF_02117	9.92e-110	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HPEMBLHF_02118	4.97e-156	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HPEMBLHF_02119	2.58e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HPEMBLHF_02120	6.29e-135	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold.
HPEMBLHF_02121	3.61e-46	-	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SecE/Sec61-gamma subunits of protein translocation complex
HPEMBLHF_02123	2.85e-286	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HPEMBLHF_02125	2.05e-255	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HPEMBLHF_02126	0.0	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HPEMBLHF_02127	1.76e-153	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HPEMBLHF_02128	8.38e-282	tig	-	-	O	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HPEMBLHF_02129	0.0	-	-	-	M	ko:K07277	-	ko00000,ko02000,ko03029	Surface antigen
HPEMBLHF_02130	1.39e-154	-	1.14.11.27	-	P	ko:K10277	-	ko00000,ko01000,ko03036	peptidyl-arginine hydroxylation
HPEMBLHF_02131	2.6e-231	-	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
HPEMBLHF_02132	2.38e-169	-	-	-	CO	-	-	-	Protein conserved in bacteria
HPEMBLHF_02134	1.46e-147	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HPEMBLHF_02135	0.0	-	-	-	P	ko:K07239	-	ko00000	AcrB/AcrD/AcrF family
HPEMBLHF_02136	5.61e-297	czcB	-	-	M	ko:K15727	-	ko00000,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPEMBLHF_02137	5.02e-294	-	-	-	MU	ko:K15725	-	ko00000,ko02000	efflux transmembrane transporter activity
HPEMBLHF_02139	3.17e-206	-	-	-	G	ko:K06867,ko:K07001	-	ko00000	response to abiotic stimulus
HPEMBLHF_02140	0.0	-	-	-	E	-	-	-	PFAM major facilitator superfamily MFS_1
HPEMBLHF_02143	1.36e-214	-	-	-	KQ	-	-	-	Hypothetical methyltransferase
HPEMBLHF_02144	2.18e-290	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HPEMBLHF_02145	0.0	ahcY	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HPEMBLHF_02146	3e-250	rgpB	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HPEMBLHF_02147	7.61e-248	-	-	-	-	-	-	-	-
HPEMBLHF_02148	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
HPEMBLHF_02149	8.66e-227	-	-	-	-	-	-	-	-
HPEMBLHF_02150	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
HPEMBLHF_02151	0.0	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RecQ zinc-binding
HPEMBLHF_02153	1.05e-292	-	-	-	M	-	-	-	Glycosyl transferases group 1
HPEMBLHF_02154	9.76e-258	-	-	-	S	-	-	-	Glycoside-hydrolase family GH114
HPEMBLHF_02155	0.0	-	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Fumarate reductase flavoprotein C-term
HPEMBLHF_02156	2.86e-133	-	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	SpoU rRNA Methylase family
HPEMBLHF_02157	8.83e-204	-	3.1.1.53	-	L	ko:K03547,ko:K05970	-	ko00000,ko01000,ko03400	3'-5' exonuclease activity
HPEMBLHF_02158	4.92e-90	-	-	-	K	-	-	-	Helix-turn-helix diphteria tox regulatory element
HPEMBLHF_02159	0.0	-	-	-	P	-	-	-	E1-E2 ATPase
HPEMBLHF_02162	2.83e-303	-	-	-	M	ko:K07267	-	ko00000,ko02000	wide pore channel activity
HPEMBLHF_02165	0.0	-	-	-	P	ko:K04759	-	ko00000,ko02000	Ferrous iron transport protein B C terminus
HPEMBLHF_02166	4.02e-48	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	iron ion homeostasis
HPEMBLHF_02167	2.48e-40	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	iron ion homeostasis
HPEMBLHF_02168	0.0	-	1.11.1.5	-	P	ko:K00428	-	ko00000,ko01000	Di-haem cytochrome c peroxidase
HPEMBLHF_02169	4.47e-228	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HPEMBLHF_02170	1.1e-131	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HPEMBLHF_02171	5.74e-241	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HPEMBLHF_02172	0.0	-	-	-	P	-	-	-	E1-E2 ATPase
HPEMBLHF_02173	0.0	-	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HPEMBLHF_02174	0.0	-	-	-	NU	ko:K02453	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Bacterial type II and III secretion system protein
HPEMBLHF_02175	2.27e-245	-	-	-	-	-	-	-	-
HPEMBLHF_02176	3.53e-207	-	-	-	-	-	-	-	-
HPEMBLHF_02177	0.0	-	-	-	NU	-	-	-	Type IV pilus assembly protein PilM;
HPEMBLHF_02178	5.43e-167	-	-	-	-	-	-	-	-
HPEMBLHF_02179	5.43e-255	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
HPEMBLHF_02180	3.57e-261	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HPEMBLHF_02181	3.29e-154	-	-	-	S	-	-	-	Protein of unknown function (DUF3313)
HPEMBLHF_02182	1.68e-313	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
HPEMBLHF_02183	2.25e-206	hisG	2.4.2.17	-	E	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
HPEMBLHF_02184	2.09e-10	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
HPEMBLHF_02188	1.1e-288	-	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HPEMBLHF_02189	6.89e-168	-	-	-	T	ko:K07657	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HPEMBLHF_02190	0.0	-	4.2.1.9	-	EG	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Dehydratase family
HPEMBLHF_02191	0.0	-	-	-	T	-	-	-	pathogenesis
HPEMBLHF_02192	1.93e-267	xerD1	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HPEMBLHF_02193	9.37e-205	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
HPEMBLHF_02194	2.23e-284	-	4.1.99.19	-	H	ko:K03150	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Biotin and Thiamin Synthesis associated domain
HPEMBLHF_02195	0.0	-	-	-	M	-	-	-	Sulfatase
HPEMBLHF_02196	2e-286	-	-	-	-	-	-	-	-
HPEMBLHF_02197	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
HPEMBLHF_02198	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF2851)
HPEMBLHF_02199	6.39e-119	-	-	-	T	-	-	-	STAS domain
HPEMBLHF_02200	0.0	-	-	-	I	-	-	-	Prenyltransferase and squalene oxidase repeat
HPEMBLHF_02201	0.0	-	-	-	I	-	-	-	Prenyltransferase and squalene oxidase repeat
HPEMBLHF_02202	1.26e-247	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NmrA-like family
HPEMBLHF_02203	0.0	-	2.1.1.182	-	IJ	ko:K02528	-	ko00000,ko01000,ko03009	Ribosomal RNA adenine dimethylases
HPEMBLHF_02204	1.45e-102	-	-	-	-	-	-	-	-
HPEMBLHF_02205	9.86e-54	-	-	-	-	-	-	-	-
HPEMBLHF_02206	3.17e-121	-	-	-	-	-	-	-	-
HPEMBLHF_02207	7.11e-300	-	-	-	V	ko:K03327	-	ko00000,ko02000	drug transmembrane transporter activity
HPEMBLHF_02208	0.0	-	-	-	P	-	-	-	Cation transport protein
HPEMBLHF_02211	9.28e-149	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HPEMBLHF_02217	5.07e-263	-	-	GT4	M	ko:K16703	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
HPEMBLHF_02219	0.0	-	-	-	M	-	-	-	pathogenesis
HPEMBLHF_02224	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPEMBLHF_02225	0.0	-	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA Topoisomerase IV
HPEMBLHF_02226	1.42e-142	-	-	-	C	-	-	-	lactate oxidation
HPEMBLHF_02227	4.44e-291	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32
HPEMBLHF_02228	0.0	-	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
HPEMBLHF_02229	0.0	-	-	-	C	-	-	-	cytochrome C peroxidase
HPEMBLHF_02230	1.21e-268	-	-	-	J	-	-	-	PFAM Endoribonuclease L-PSP
HPEMBLHF_02232	0.0	-	1.8.1.2	-	P	ko:K00381	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite and sulphite reductase 4Fe-4S domain
HPEMBLHF_02233	3.23e-174	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPEMBLHF_02234	2.03e-180	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPEMBLHF_02235	1.02e-231	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	NMT1/THI5 like
HPEMBLHF_02236	0.0	-	2.7.1.25, 2.7.7.4	-	P	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily
HPEMBLHF_02237	9.99e-216	-	2.7.7.4	-	EH	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoadenosine phosphosulfate reductase family
HPEMBLHF_02238	3.3e-167	-	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Phosphoadenosine phosphosulfate reductase family
HPEMBLHF_02239	1.25e-212	-	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HPEMBLHF_02240	2.46e-147	phoU	-	-	P	ko:K02039	-	ko00000	negative regulation of phosphate transmembrane transport
HPEMBLHF_02241	4.85e-185	-	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HPEMBLHF_02242	0.0	-	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPEMBLHF_02243	0.0	pstC	-	-	P	ko:K02037,ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPEMBLHF_02244	8.14e-218	-	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	PBP superfamily domain
HPEMBLHF_02245	5.03e-183	-	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HPEMBLHF_02246	3.91e-135	-	-	-	P	ko:K02039	-	ko00000	PhoU domain
HPEMBLHF_02247	2.06e-232	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
HPEMBLHF_02248	7.65e-101	-	-	-	M	ko:K06077	-	ko00000	Glycine zipper 2TM domain
HPEMBLHF_02250	0.0	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Insulinase (Peptidase family M16)
HPEMBLHF_02251	1.61e-96	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HPEMBLHF_02252	4.02e-143	-	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
HPEMBLHF_02253	1.19e-98	-	-	-	S	-	-	-	Maltose acetyltransferase
HPEMBLHF_02254	3.66e-210	-	-	-	L	-	-	-	Elongator protein 3, MiaB family, Radical SAM
HPEMBLHF_02255	5.88e-229	-	-	-	J	-	-	-	Belongs to the universal ribosomal protein uS2 family
HPEMBLHF_02256	1.98e-100	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HPEMBLHF_02257	9.17e-70	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
HPEMBLHF_02258	2.53e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HPEMBLHF_02259	1.54e-163	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Amino acid kinase family
HPEMBLHF_02260	1.35e-207	-	-	-	M	-	-	-	Mechanosensitive ion channel
HPEMBLHF_02261	7.26e-152	-	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
HPEMBLHF_02262	0.0	-	-	-	S	-	-	-	Sodium:neurotransmitter symporter family
HPEMBLHF_02263	0.0	-	-	-	-	-	-	-	-
HPEMBLHF_02264	7.28e-37	-	-	-	J	-	-	-	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HPEMBLHF_02265	2.08e-144	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HPEMBLHF_02267	3.9e-306	-	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HPEMBLHF_02268	4.86e-110	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07305,ko:K12267	-	ko00000,ko01000	peptide-methionine (R)-S-oxide reductase activity
HPEMBLHF_02269	4.86e-258	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HPEMBLHF_02270	2.61e-298	nupG	-	-	G	ko:K03289,ko:K03301,ko:K08218,ko:K11537	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
HPEMBLHF_02273	3.83e-240	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HPEMBLHF_02274	4.46e-238	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HPEMBLHF_02275	0.0	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPEMBLHF_02276	6.51e-226	-	-	-	M	ko:K01993	-	ko00000	HlyD family secretion protein
HPEMBLHF_02277	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HPEMBLHF_02278	3.85e-194	-	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	CDP-alcohol phosphatidyltransferase
HPEMBLHF_02279	4.03e-120	-	-	-	-	-	-	-	-
HPEMBLHF_02280	6.16e-198	-	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HPEMBLHF_02281	0.0	-	-	-	M	-	-	-	Bacterial membrane protein, YfhO
HPEMBLHF_02282	0.0	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GcpE protein
HPEMBLHF_02283	9.4e-148	-	-	-	IQ	-	-	-	RmlD substrate binding domain
HPEMBLHF_02284	3.08e-286	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
HPEMBLHF_02285	0.0	-	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	thiolester hydrolase activity
HPEMBLHF_02286	7.26e-285	-	-	-	IQ	-	-	-	Beta-ketoacyl synthase, C-terminal domain
HPEMBLHF_02287	1.56e-259	-	2.3.1.47	-	H	ko:K00652	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HPEMBLHF_02291	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HPEMBLHF_02292	8.6e-310	-	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
HPEMBLHF_02293	1.02e-175	hypB	-	-	KO	ko:K04652	-	ko00000,ko03110	CobW/HypB/UreG, nucleotide-binding domain
HPEMBLHF_02294	0.0	-	-	-	O	ko:K04656	-	ko00000	HypF finger
HPEMBLHF_02295	9.56e-51	-	-	-	O	ko:K04653	-	ko00000	HupF/HypC family
HPEMBLHF_02296	4.64e-254	-	-	-	O	ko:K04654	-	ko00000	Hydrogenase formation hypA family
HPEMBLHF_02297	3.85e-236	-	-	-	O	ko:K04655	-	ko00000	AIR synthase related protein, N-terminal domain
HPEMBLHF_02298	4.27e-275	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
HPEMBLHF_02299	0.0	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
HPEMBLHF_02300	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	MreB/Mbl protein
HPEMBLHF_02301	2.2e-61	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HPEMBLHF_02302	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HPEMBLHF_02303	2.16e-98	-	-	-	S	-	-	-	peptidase
HPEMBLHF_02304	0.0	-	-	-	P	ko:K03306	-	ko00000	phosphate transporter
HPEMBLHF_02308	5.42e-296	-	-	-	-	-	-	-	-
HPEMBLHF_02309	0.0	-	-	-	D	-	-	-	Chain length determinant protein
HPEMBLHF_02310	7.55e-142	-	-	-	M	-	-	-	Polysaccharide biosynthesis/export protein
HPEMBLHF_02312	1.09e-148	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HPEMBLHF_02313	1.67e-249	-	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
HPEMBLHF_02314	4.06e-286	pgk	2.7.2.3	-	G	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
HPEMBLHF_02315	2.42e-244	-	-	-	-	-	-	-	-
HPEMBLHF_02316	6.06e-282	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	myo-inosose-2 dehydratase activity
HPEMBLHF_02318	1.02e-203	dapA	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
HPEMBLHF_02319	4.14e-175	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate reductase, N-terminus
HPEMBLHF_02320	6.99e-120	-	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HPEMBLHF_02321	1.38e-181	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HPEMBLHF_02322	4.63e-225	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HPEMBLHF_02323	2.25e-205	-	-	-	M	-	-	-	Peptidase family M23
HPEMBLHF_02328	1.75e-110	-	-	-	S	-	-	-	Acetyltransferase (GNAT) family
HPEMBLHF_02329	1.48e-135	-	-	-	C	-	-	-	Nitroreductase family
HPEMBLHF_02330	0.0	-	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence
HPEMBLHF_02331	1.66e-87	-	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HPEMBLHF_02332	8.8e-239	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HPEMBLHF_02333	8.07e-174	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	tRNA (Guanine-1)-methyltransferase
HPEMBLHF_02334	2.05e-28	-	-	-	-	-	-	-	-
HPEMBLHF_02335	2.55e-243	-	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
HPEMBLHF_02336	9e-228	-	-	-	S	-	-	-	PFAM Sel1 domain protein repeat-containing protein
HPEMBLHF_02337	5.74e-54	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HPEMBLHF_02338	0.0	-	-	-	J	ko:K07576	-	ko00000	Beta-Casp domain
HPEMBLHF_02339	1.55e-83	-	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	ArsC family
HPEMBLHF_02340	3.54e-181	-	-	-	P	ko:K10716	-	ko00000,ko02000	domain protein
HPEMBLHF_02341	0.0	-	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Carbohydrate phosphorylase
HPEMBLHF_02342	2.04e-258	tdh	1.1.1.103	-	E	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
HPEMBLHF_02343	1.56e-160	-	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HPEMBLHF_02345	9.2e-157	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HPEMBLHF_02346	3.92e-115	-	-	-	-	-	-	-	-
HPEMBLHF_02349	0.0	-	-	-	L	-	-	-	DNA restriction-modification system
HPEMBLHF_02352	2.94e-163	-	-	-	S	-	-	-	PFAM Sel1 domain protein repeat-containing protein
HPEMBLHF_02354	4.82e-174	-	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HPEMBLHF_02356	5e-309	-	-	-	P	ko:K14445	-	ko00000,ko02000	Citrate transporter
HPEMBLHF_02357	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HPEMBLHF_02358	6.35e-257	mtrC	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPEMBLHF_02359	0.0	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HPEMBLHF_02361	0.0	-	-	-	G	-	-	-	alpha-galactosidase
HPEMBLHF_02362	2.39e-06	-	-	-	-	-	-	-	-
HPEMBLHF_02363	0.0	poxB	1.2.3.3, 1.2.5.1	-	EH	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Thiamine pyrophosphate enzyme, central domain
HPEMBLHF_02364	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPEMBLHF_02365	3.56e-179	-	-	-	L	ko:K10800	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	uracil-dna glycosylase
HPEMBLHF_02366	2.66e-227	-	2.7.1.11	-	G	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Phosphofructokinase
HPEMBLHF_02367	1.2e-267	-	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Male sterility protein
HPEMBLHF_02368	5.28e-203	-	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HPEMBLHF_02371	0.0	-	-	-	C	-	-	-	Acetyl-CoA hydrolase/transferase C-terminal domain
HPEMBLHF_02372	1.06e-188	-	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
HPEMBLHF_02373	0.0	-	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Na+-transporting oxaloacetate decarboxylase beta subunit
HPEMBLHF_02374	5.64e-54	-	-	-	I	-	-	-	PFAM biotin lipoyl attachment domain-containing protein
HPEMBLHF_02376	0.0	-	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Carboxyl transferase domain
HPEMBLHF_02377	1.5e-100	-	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Glyoxalase-like domain
HPEMBLHF_02378	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HPEMBLHF_02379	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HPEMBLHF_02382	0.0	-	-	-	S	-	-	-	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HPEMBLHF_02383	4.48e-297	-	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HPEMBLHF_02384	1.05e-112	-	-	-	P	-	-	-	Rhodanese-like domain
HPEMBLHF_02385	7.7e-149	-	-	-	S	-	-	-	Protein of unknown function (DUF1573)
HPEMBLHF_02386	3.41e-184	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase (SPase) II
HPEMBLHF_02387	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HPEMBLHF_02388	1.29e-235	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HPEMBLHF_02389	7.43e-256	-	-	-	S	-	-	-	Peptidase family M28
HPEMBLHF_02390	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
HPEMBLHF_02391	1.88e-55	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPEMBLHF_02392	2.17e-88	-	-	-	S	ko:K09793	-	ko00000	Protein of unknown function (DUF456)
HPEMBLHF_02393	1.8e-203	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HPEMBLHF_02397	5.77e-28	-	-	-	M	-	-	-	self proteolysis